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Chris D. Pacheco - Publications

Affiliations: 
2002-2008 University of Michigan, Ann Arbor, Ann Arbor, MI 
 2008-2010 Whitehead Institute for Biomedical Research (MIT) 
Area:
Neurodegeneration
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10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Krishnan R, Goodman JL, Mukhopadhyay S, Pacheco CD, Lemke EA, Deniz AA, Lindquist S. Conserved features of intermediates in amyloid assembly determine their benign or toxic states. Proceedings of the National Academy of Sciences of the United States of America. 109: 11172-7. PMID 22745165 DOI: 10.1073/Pnas.1209527109  0.504
2011 Dumitriu A, Pacheco CD, Wilk JB, Strathearn KE, Latourelle JC, Goldwurm S, Pezzoli G, Rochet JC, Lindquist S, Myers RH. Cyclin-G-associated kinase modifies α-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study. Human Molecular Genetics. 20: 1478-87. PMID 21258085 DOI: 10.1093/Hmg/Ddr026  0.5
2010 Elrick MJ, Pacheco CD, Yu T, Dadgar N, Shakkottai VG, Ware C, Paulson HL, Lieberman AP. Conditional Niemann-Pick C mice demonstrate cell autonomous Purkinje cell neurodegeneration. Human Molecular Genetics. 19: 837-47. PMID 20007718 DOI: 10.1093/Hmg/Ddp552  0.677
2009 Pacheco CD, Elrick MJ, Lieberman AP. Tau normal function influences Niemann-Pick type C disease pathogenesis in mice and modulates autophagy in NPC1-deficient cells. Autophagy. 5: 548-50. PMID 19332999 DOI: 10.4161/auto.5.4.8364  0.705
2009 Pacheco CD, Elrick MJ, Lieberman AP. Tau deletion exacerbates the phenotype of Niemann-Pick type C mice and implicates autophagy in pathogenesis. Human Molecular Genetics. 18: 956-65. PMID 19074461 DOI: 10.1093/Hmg/Ddn423  0.701
2008 Pacheco CD, Lieberman AP. The pathogenesis of Niemann-Pick type C disease: a role for autophagy? Expert Reviews in Molecular Medicine. 10: e26. PMID 18782459 DOI: 10.1017/S146239940800080X  0.672
2007 Hughes ED, Qu YY, Genik SJ, Lyons RH, Pacheco CD, Lieberman AP, Samuelson LC, Nasonkin IO, Camper SA, Van Keuren ML, Saunders TL. Genetic variation in C57BL/6 ES cell lines and genetic instability in the Bruce4 C57BL/6 ES cell line. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 549-58. PMID 17828574 DOI: 10.1007/S00335-007-9054-0  0.552
2007 Pacheco CD, Lieberman AP. Lipid trafficking defects increase Beclin-1 and activate autophagy in Niemann-Pick type C disease. Autophagy. 3: 487-9. PMID 17611388 DOI: 10.4161/Auto.4586  0.681
2007 Pacheco CD, Kunkel R, Lieberman AP. Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects. Human Molecular Genetics. 16: 1495-503. PMID 17468177 DOI: 10.1093/hmg/ddm100  0.67
2004 Schauber CA, Tuerk MJ, Pacheco CD, Escarpe PA, Veres G. Lentiviral vectors pseudotyped with baculovirus gp64 efficiently transduce mouse cells in vivo and show tropism restriction against hematopoietic cell types in vitro. Gene Therapy. 11: 266-75. PMID 14737086 DOI: 10.1038/sj.gt.3302170  0.332
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