Jamil S. Saad, Ph.D. - Publications

Affiliations: 
2002 Emory University, Atlanta, GA 
Area:
physical and synthetic chemistry

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Vlach J, Eastep GN, Ghanam RH, Watanabe SM, Carter C, Saad JS. Structural basis for targeting avian sarcoma virus Gag polyprotein to the plasma membrane for virus assembly. The Journal of Biological Chemistry. PMID 30309983 DOI: 10.1074/jbc.RA118.003944  0.32
2018 Watanabe SM, Medina G, Eastep GN, Ghanam RH, Vlach J, Saad JS, Carter C. The matrix domain of the Gag protein from avian sarcoma virus contains a PI(4,5)P2-binding site that targets Gag to the cell periphery. The Journal of Biological Chemistry. PMID 30309982 DOI: 10.1074/jbc.RA118.003947  0.32
2016 Agamasu C, Ghanam RH, Xu F, Sun Y, Chen Y, Saad JS. The Interplay Between Calmodulin and Membrane Interactions with the Pleckstrin Homology Domain of Akt. The Journal of Biological Chemistry. PMID 27872186 DOI: 10.1074/jbc.M116.752816  0.32
2016 Burton RL, Geno KA, Saad JS, Nahm MH. Pneumococcus with the "6E" cps locus produces serotype 6B capsular polysaccharide. Journal of Clinical Microbiology. PMID 26818670 DOI: 10.1128/JCM.03194-15  0.84
2016 Chang BJ, Samal AB, Vlach J, Fernandez TF, Brooke D, Prevelige PE, Saad JS. Identification of the Calmodulin-Binding Domains of Fas Death Receptor. Plos One. 11: e0146493. PMID 26735300 DOI: 10.1371/journal.pone.0146493  0.84
2015 Agamasu C, Ghanam RH, Saad JS. Structural and Biophysical Characterization of the Interactions between Calmodulin and the Pleckstrin Homology Domain of Akt. The Journal of Biological Chemistry. 290: 27403-13. PMID 26391397 DOI: 10.1074/jbc.M115.673939  0.84
2015 Saad JS, Muriaux DM. Editorial: Role of lipids in virus assembly. Frontiers in Microbiology. 6: 410. PMID 25999935 DOI: 10.3389/fmicb.2015.00410  0.84
2015 Lampel A, Bram Y, Ezer A, Shaltiel-Kario R, Saad JS, Bacharach E, Gazit E. Targeting the Early Step of Building Block Organization in Viral Capsid Assembly. Acs Chemical Biology. PMID 25997366 DOI: 10.1021/acschembio.5b00347  0.84
2015 Vlach J, Saad JS. Structural and molecular determinants of HIV-1 Gag binding to the plasma membrane. Frontiers in Microbiology. 6: 232. PMID 25852680 DOI: 10.3389/fmicb.2015.00232  0.84
2014 Vlach J, Saad JS. HIV: a vicTIM. Trends in Microbiology. 22: 603-4. PMID 25438615 DOI: 10.1016/j.tim.2014.09.008  0.84
2014 Vlach J, Samal AB, Saad JS. Solution structure of calmodulin bound to the binding domain of the HIV-1 matrix protein. The Journal of Biological Chemistry. 289: 8697-705. PMID 24500712 DOI: 10.1074/jbc.M113.543694  0.84
2014 Calix JJ, Brady AM, Du VY, Saad JS, Nahm MH. Spectrum of pneumococcal serotype 11A variants results from incomplete loss of capsule O-acetylation. Journal of Clinical Microbiology. 52: 758-65. PMID 24352997 DOI: 10.1128/JCM.02695-13  0.84
2013 Oliver MB, van der Linden MP, Küntzel SA, Saad JS, Nahm MH. Discovery of Streptococcus pneumoniae serotype 6 variants with glycosyltransferases synthesizing two differing repeating units. The Journal of Biological Chemistry. 288: 25976-85. PMID 23897812 DOI: 10.1074/jbc.M113.480152  0.84
2013 Fernandez TF, Samal AB, Bedwell GJ, Chen Y, Saad JS. Structural and biophysical characterization of the interactions between the death domain of Fas receptor and calmodulin. The Journal of Biological Chemistry. 288: 21898-908. PMID 23760276 DOI: 10.1074/jbc.M113.471821  0.84
2013 Vlach J, Saad JS. Trio engagement via plasma membrane phospholipids and the myristoyl moiety governs HIV-1 matrix binding to bilayers. Proceedings of the National Academy of Sciences of the United States of America. 110: 3525-30. PMID 23401539 DOI: 10.1073/pnas.1216655110  0.84
2012 Calix JJ, Saad JS, Brady AM, Nahm MH. Structural characterization of Streptococcus pneumoniae serotype 9A capsule polysaccharide reveals role of glycosyl 6-O-acetyltransferase wcjE in serotype 9V capsule biosynthesis and immunogenicity. The Journal of Biological Chemistry. 287: 13996-4003. PMID 22367197 DOI: 10.1074/jbc.M112.346924  0.84
2012 Ghanam RH, Samal AB, Fernandez TF, Saad JS. Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly. Frontiers in Microbiology. 3: 55. PMID 22363329 DOI: 10.3389/fmicb.2012.00055  0.84
2011 Saad JS, Marzilli PA, Intini FP, Natile G, Marzilli LG. Single-stranded oligonucleotide adducts formed by Pt complexes favoring left-handed base canting: steric effect of flanking residues and relevance to DNA adducts formed by Pt anticancer drugs. Inorganic Chemistry. 50: 8608-20. PMID 21819051 DOI: 10.1021/ic2011716  0.84
2011 Samal AB, Ghanam RH, Fernandez TF, Monroe EB, Saad JS. NMR, biophysical, and biochemical studies reveal the minimal Calmodulin binding domain of the HIV-1 matrix protein. The Journal of Biological Chemistry. 286: 33533-43. PMID 21799007 DOI: 10.1074/jbc.M111.273623  0.84
2011 Saad JS, Benedetti M, Natile G, Marzilli LG. NMR studies of models having the Pt(d(GpG)) 17-membered macrocyclic ring formed in DNA by platinum anticancer drugs: Pt complexes with bulky chiral diamine ligands. Inorganic Chemistry. 50: 4559-71. PMID 21510625 DOI: 10.1021/ic200259s  0.84
2010 Ghanam RH, Fernandez TF, Fledderman EL, Saad JS. Binding of calmodulin to the HIV-1 matrix protein triggers myristate exposure. The Journal of Biological Chemistry. 285: 41911-20. PMID 20956522 DOI: 10.1074/jbc.M110.179093  0.84
2010 Fledderman EL, Fujii K, Ghanam RH, Waki K, Prevelige PE, Freed EO, Saad JS. Myristate exposure in the human immunodeficiency virus type 1 matrix protein is modulated by pH. Biochemistry. 49: 9551-62. PMID 20886905 DOI: 10.1021/bi101245j  0.84
2010 Saad JS, Benedetti M, Natile G, Marzilli LG. Basic coordination chemistry relevant to DNA adducts formed by the cisplatin anticancer drug. NMR studies on compounds with sterically crowded chiral ligands. Inorganic Chemistry. 49: 5573-83. PMID 20496875 DOI: 10.1021/ic100494f  0.84
2010 Valentine KG, Peterson RW, Saad JS, Summers MF, Xu X, Ames JB, Wand AJ. Reverse micelle encapsulation of membrane-anchored proteins for solution NMR studies. Structure (London, England : 1993). 18: 9-16. PMID 20152148 DOI: 10.1016/j.str.2009.11.010  0.32
2010 Hamard-Peron E, Juillard F, Saad JS, Roy C, Roingeard P, Summers MF, Darlix JL, Picart C, Muriaux D. Targeting of murine leukemia virus gag to the plasma membrane is mediated by PI(4,5)P2/PS and a polybasic region in the matrix. Journal of Virology. 84: 503-15. PMID 19828619 DOI: 10.1128/JVI.01134-09  0.84
2009 Saad JS, Natile G, Marzilli LG. Origins of the distortions in the base pair step adjacent to platinum anticancer drug-DNA adducts. Fundamental NMR solution studies utilizing right-handed cross-link models having 5'- and 3'-flanking residues. Journal of the American Chemical Society. 131: 12314-24. PMID 19655752 DOI: 10.1021/ja903787m  0.84
2009 Hamard-Peron E, Juilliard F, Saad JS, Roy C, Roingeard P, Summers MF, Darlix JL, Picart C, Muriaux D. Targeting of MuLV gag to the plasma membrane is mediated by PI(4,5)P2 and phosphatidylserine Retrovirology. 6: O15.  0.84
2008 Saad JS, Ablan SD, Ghanam RH, Kim A, Andrews K, Nagashima K, Soheilian F, Freed EO, Summers MF. Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting. Journal of Molecular Biology. 382: 434-47. PMID 18657545 DOI: 10.1016/j.jmb.2008.07.027  0.84
2007 Saad JS, Kim A, Ghanam RH, Dalton AK, Vogt VM, Wu Z, Lu W, Summers MF. Mutations that mimic phosphorylation of the HIV-1 matrix protein do not perturb the myristyl switch. Protein Science : a Publication of the Protein Society. 16: 1793-7. PMID 17656588 DOI: 10.1110/ps.072987607  0.84
2007 Saad JS, Loeliger E, Luncsford P, Liriano M, Tai J, Kim A, Miller J, Joshi A, Freed EO, Summers MF. Point mutations in the HIV-1 matrix protein turn off the myristyl switch. Journal of Molecular Biology. 366: 574-85. PMID 17188710 DOI: 10.1016/j.jmb.2006.11.068  0.84
2006 Saad JS, Miller J, Tai J, Kim A, Ghanam RH, Summers MF. Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly. Proceedings of the National Academy of Sciences of the United States of America. 103: 11364-9. PMID 16840558 DOI: 10.1073/pnas.0602818103  0.84
2003 Benedetti M, Saad JS, Marzilli LG, Natile G. Chiral discrimination in the formation reaction and at equilibrium for N,N,N′9N′-tetramethyl-1,2-diaminocyclohexane-PtG2 complexes Dalton Transactions. 872-879. DOI: 10.1039/b210616g  0.84
2002 Saad JS, Scarcia T, Natile G, Marzilli LG. Factors influencing conformer equilibria in retro models of cisplatin-DNA adducts as revealed by moderately dynamic (N,N'-dimethyl-2,3-diaminobutane)PtG(2) retro models (G = a guanine derivative). Inorganic Chemistry. 41: 4923-35. PMID 12230397 DOI: 10.1021/ic011115m  0.84
2002 Sullivan ST, Saad JS, Fanizzi FP, Marzilli LG. Dramatic 5'-residue effect on conformer distribution of short oligonucleotide retro models of the cisplatin-DNA cross-link: implications for the Lippard and cross-link distorted base pair steps present in cisplatin-DNA duplex adducts. Journal of the American Chemical Society. 124: 1558-9. PMID 11853413  0.84
2002 Saad JS, Scarcia T, Shinozuka K, Natile G, Marzilli LG. Modification of second-sphere communication, leading to an unusually high abundance of the head-to-head conformer of cisplatin cross-link retro models. Inorganic Chemistry. 41: 546-57. PMID 11825082 DOI: 10.1021/ic010758z  0.84
2002 Sullivan ST, Saad JS, Fanizzi FP, Marzilli LG. Dramatic 5′-residue effect on conformer distribution of short oligonucleotide retro models of the cisplatin-DNA cross-link: Implications for the lippard and cross-link distorted base pair steps present in cisplatin-DNA duplex adducts Journal of the American Chemical Society. 124: 1558-1559. DOI: 10.1021/ja0121742  0.84
2001 Marzilli LG, Saad JS, Kuklenyik Z, Keating KA, Xu Y. Relationship of solution and protein-bound structures of DNA duplexes with the major intrastrand cross-link lesions formed on cisplatin binding to DNA. Journal of the American Chemical Society. 123: 2764-70. PMID 11456962 DOI: 10.1021/ja0007915  0.84
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