Luke H. Bradley, Ph.D. - Publications

2001 Ohio State University, Columbus, Columbus, OH 

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Gash DM, Gerhardt GA, Bradley LH, Wagner R, Slevin JT. GDNF clinical trials for Parkinson's disease: a critical human dimension. Cell and Tissue Research. PMID 32830288 DOI: 10.1007/s00441-020-03269-8  1
2018 Grondin R, Littrell OM, Zhang Z, Ai Y, Huettl P, Pomerleau F, Quintero JE, Andersen AH, Stenslik MJ, Bradley LH, Lemmon J, O'Neill MJ, Gash DM, Gerhardt GA. GDNF revisited: A novel mammalian cell-derived variant form of GDNF increases dopamine turnover and improves brain biodistribution. Neuropharmacology. PMID 29857941 DOI: 10.1016/j.neuropharm.2018.05.014  1
2018 Stenslik MJ, Evans A, Pomerleau F, Weeks R, Huettl P, Foreman E, Turchan-Cholewo J, Andersen A, Cass WA, Zhang Z, Grondin RC, Gash DM, Gerhardt GA, Bradley LH. Methodology and effects of repeated intranasal delivery of DNSP-11 in awake Rhesus macaques. Journal of Neuroscience Methods. PMID 29614295 DOI: 10.1016/j.jneumeth.2018.03.006  1
2015 Stenslik MJ, Potts LF, Sonne JW, Cass WA, Turchan-Cholewo J, Pomerleau F, Huettl P, Ai Y, Gash DM, Gerhardt GA, Bradley LH. Methodology and effects of repeated intranasal delivery of DNSP-11 in a rat model of Parkinson's disease. Journal of Neuroscience Methods. 251: 120-9. PMID 25999268 DOI: 10.1016/j.jneumeth.2015.05.006  1
2014 Bradley LH. High-quality combinatorial protein libraries using the binary patterning approach. Methods in Molecular Biology (Clifton, N.J.). 1216: 117-28. PMID 25213413 DOI: 10.1007/978-1-4939-1486-9_6  1
2014 Fuqua JL, Littrell OM, Lundblad M, Turchan-Cholewo J, Abdelmoti LG, Galperin E, Bradley LH, Cass WA, Gash DM, Gerhardt GA. Dynamic changes in dopamine neuron function after DNSP-11 treatment: effects in vivo and increased ERK 1/2 phosphorylation in vitro. Peptides. 54: 1-8. PMID 24406899 DOI: 10.1016/j.peptides.2013.12.007  1
2013 Hardy PA, Keeley D, Schorn G, Forman E, Ai Y, Venugopalan R, Zhang Z, Bradley LH. Convection enhanced delivery of different molecular weight tracers of gadolinium-tagged polylysine. Journal of Neuroscience Methods. 219: 169-75. PMID 23912025 DOI: 10.1016/j.jneumeth.2013.07.013  1
2013 Littrell OM, Fuqua JL, Richardson AD, Turchan-Cholewo J, Hascup ER, Huettl P, Pomerleau F, Bradley LH, Gash DM, Gerhardt GA. A synthetic five amino acid propeptide increases dopamine neuron differentiation and neurochemical function. Neuropeptides. 47: 43-9. PMID 22981157 DOI: 10.1016/j.npep.2012.08.004  1
2012 Magnani R, Chaffin B, Dick E, Bricken ML, Houtz RL, Bradley LH. Utilization of a calmodulin lysine methyltransferase co-expression system for the generation of a combinatorial library of post-translationally modified proteins. Protein Expression and Purification. 86: 83-8. PMID 23036357 DOI: 10.1016/j.pep.2012.09.012  1
2012 Arai R, Kobayashi N, Kimura A, Sato T, Matsuo K, Wang AF, Platt JM, Bradley LH, Hecht MH. Domain-swapped dimeric structure of a stable and functional de novo four-helix bundle protein, WA20. The Journal of Physical Chemistry. B. 116: 6789-97. PMID 22397676 DOI: 10.1021/jp212438h  1
2012 Sexton T, Hitchcook LJ, Rodgers DW, Bradley LH, Hersh LB. Active site mutations change the cleavage specificity of neprilysin. Plos One. 7: e32343. PMID 22384224 DOI: 10.1371/journal.pone.0032343  1
2011 Kelps KA, Turchan-Cholewo J, Hascup ER, Taylor TL, Gash DM, Gerhardt GA, Bradley LH. Evaluation of the physical and in vitro protective activity of three synthetic peptides derived from the pro- and mature GDNF sequence. Neuropeptides. 45: 213-8. PMID 21507484 DOI: 10.1016/j.npep.2011.03.003  1
2011 Fisher MA, McKinley KL, Bradley LH, Viola SR, Hecht MH. De novo designed proteins from a library of artificial sequences function in Escherichia coli and enable cell growth. Plos One. 6: e15364. PMID 21245923 DOI: 10.1371/journal.pone.0015364  1
2011 Bradley LH, Bricken ML, Randle C. Expression, purification, and characterization of proteins from high-quality combinatorial libraries of the mammalian calmodulin central linker. Protein Expression and Purification. 75: 186-91. PMID 20732425 DOI: 10.1016/j.pep.2010.08.007  1
2010 Bradley LH, Fuqua J, Richardson A, Turchan-Cholewo J, Ai Y, Kelps KA, Glass JD, He X, Zhang Z, Grondin R, Littrell OM, Huettl P, Pomerleau F, Gash DM, Gerhardt GA. Dopamine neuron stimulating actions of a GDNF propeptide. Plos One. 5: e9752. PMID 20305789 DOI: 10.1371/journal.pone.0009752  1
2009 Patel SC, Bradley LH, Jinadasa SP, Hecht MH. Cofactor binding and enzymatic activity in an unevolved superfamily of de novo designed 4-helix bundle proteins. Protein Science : a Publication of the Protein Society. 18: 1388-400. PMID 19544578 DOI: 10.1002/pro.147  1
2007 Bradley LH, Wei Y, Thumfort P, Wurth C, Hecht MH. Protein design by binary patterning of polar and nonpolar amino acids. Methods in Molecular Biology (Clifton, N.J.). 352: 155-66. PMID 17041264 DOI: 10.1385/1-59745-187-8:155  1
2006 Bradley LH, Thumfort PP, Hecht MH. De novo proteins from binary-patterned combinatorial libraries. Methods in Molecular Biology (Clifton, N.J.). 340: 53-69. PMID 16957332 DOI: 10.1385/1-59745-116-9:53  1
2005 Bradley LH, Kleiner RE, Wang AF, Hecht MH, Wood DW. An intein-based genetic selection allows the construction of a high-quality library of binary patterned de novo protein sequences. Protein Engineering, Design & Selection : Peds. 18: 201-7. PMID 15849217 DOI: 10.1093/protein/gzi020  1
2004 Hecht MH, Das A, Go A, Bradley LH, Wei Y. De novo proteins from designed combinatorial libraries. Protein Science : a Publication of the Protein Society. 13: 1711-23. PMID 15215517 DOI: 10.1110/ps.04690804  1
2001 Bradley LH, Swenson RP. Role of hydrogen bonding interactions to N(3)H of the flavin mononucleotide cofactor in the modulation of the redox potentials of the Clostridium beijerinckii flavodoxin. Biochemistry. 40: 8686-95. PMID 11467928 DOI: 10.1021/bi010571j  1
2001 Chang F, Bradley LH, Swenson RP. Evaluation of the hydrogen bonding interactions and their effects on the oxidation-reduction potentials for the riboflavin complex of the Desulfovibrio vulgaris flavodoxin. Biochimica Et Biophysica Acta. 1504: 319-28. PMID 11245795 DOI: 10.1016/S0005-2728(00)00260-7  1
1999 Bradley LH, Swenson RP. Role of glutamate-59 hydrogen bonded to N(3)H of the flavin mononucleotide cofactor in the modulation of the redox potentials of the Clostridium beijerinckii flavodoxin. Glutamate-59 is not responsible for the pH dependency but contributes to the stabilization of the flavin semiquinone. Biochemistry. 38: 12377-86. PMID 10493805 DOI: 10.1021/bi991172f  1
1997 Christoff JJ, Bradley L, Miller DD, Lei L, Rodriguez F, Fraundorfer P, Romstedt K, Shams G, Feller DR. Synthesis and evaluation of trimetoquinol derivatives: novel thromboxane A2/prostaglandin H2 antagonists with diminished beta-adrenergic agonist activity. Journal of Medicinal Chemistry. 40: 85-91. PMID 9016331 DOI: 10.1021/jm950896w  1
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