Kirk D. Beebe, Ph.D. - Publications

Affiliations: 
2000 Ohio State University, Columbus, Columbus, OH 
Area:
chemical biology, medicinal chemistry

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Beebe K, Kennedy AD. Sharpening Precision Medicine by a Thorough Interrogation of Metabolic Individuality Computational and Structural Biotechnology Journal. 14: 97-105. DOI: 10.1016/j.csbj.2016.01.001  0.92
2014 Beebe K, Sampey B, Watkins SM, Milburn M, Eckhart AD. Understanding the apothecaries within: the necessity of a systematic approach for defining the chemical output of the human microbiome. Clinical and Translational Science. 7: 74-81. PMID 24422665 DOI: 10.1111/cts.12131  0.92
2012 Eckhart AD, Beebe K, Milburn M. Metabolomics as a Key Integrator for "Omic" Advancement of Personalized Medicine and Future Therapies Clinical and Translational Science. 5: 285-288. PMID 22686208 DOI: 10.1111/j.1752-8062.2011.00388.x  0.92
2012 Spitale RC, Cheng MY, Chun KA, Gorell ES, Munoz CA, Kern DG, Wood SM, Knaggs HE, Wulff J, Beebe KD, Chang AL. Differential effects of dietary supplements on metabolomic profile of smokers versus non-smokers. Genome Medicine. 4: 14. PMID 22360970 DOI: 10.1186/gm313  0.92
2011 Macotela Y, Emanuelli B, Bång AM, Espinoza DO, Boucher J, Beebe K, Gall W, Kahn CR. Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism. Plos One. 6: e21187. PMID 21731668 DOI: 10.1371/journal.pone.0021187  0.92
2010 Gall WE, Beebe K, Lawton KA, Adam KP, Mitchell MW, Nakhle PJ, Ryals JA, Milburn MV, Nannipieri M, Camastra S, Natali A, Ferrannini E. alpha-hydroxybutyrate is an early biomarker of insulin resistance and glucose intolerance in a nondiabetic population. Plos One. 5: e10883. PMID 20526369 DOI: 10.1371/journal.pone.0010883  0.92
2009 Guo M, Chong YE, Shapiro R, Beebe K, Yang XL, Schimmel P. Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature. 462: 808-12. PMID 20010690 DOI: 10.1038/nature08612  0.92
2009 Guo M, Chong YE, Beebe K, Shapiro R, Yang XL, Schimmel P. The C-Ala domain brings together editing and aminoacylation functions on one tRNA. Science (New York, N.Y.). 325: 744-7. PMID 19661429 DOI: 10.1126/science.1174343  0.92
2009 Ohta T, Masutomi N, Tsutsui N, Sakairi T, Mitchell M, Milburn MV, Ryals JA, Beebe KD, Guo L. Untargeted metabolomic profiling as an evaluative tool of fenofibrate-induced toxicology in Fischer 344 male rats. Toxicologic Pathology. 37: 521-35. PMID 19458390 DOI: 10.1177/0192623309336152  0.92
2008 Beebe K, Mock M, Merriman E, Schimmel P. Distinct domains of tRNA synthetase recognize the same base pair. Nature. 451: 90-3. PMID 18172502 DOI: 10.1038/nature06454  0.92
2007 Beebe K, Waas W, Druzina Z, Guo M, Schimmel P. A universal plate format for increased throughput of assays that monitor multiple aminoacyl transfer RNA synthetase activities. Analytical Biochemistry. 368: 111-21. PMID 17603003 DOI: 10.1016/j.ab.2007.05.013  0.92
2006 Lee JW, Beebe K, Nangle LA, Jang J, Longo-Guess CM, Cook SA, Davisson MT, Sundberg JP, Schimmel P, Ackerman SL. Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration. Nature. 443: 50-5. PMID 16906134 DOI: 10.1038/nature05096  0.92
2004 Schimmel P, Beebe K. Molecular biology: genetic code seizes pyrrolysine. Nature. 431: 257-8. PMID 15372017 DOI: 10.1038/431257a  0.92
2004 Beebe K, Merriman E, Ribas De Pouplana L, Schimmel P. A domain for editing by an archaebacterial tRNA synthetase. Proceedings of the National Academy of Sciences of the United States of America. 101: 5958-63. PMID 15079065 DOI: 10.1073/pnas.0401530101  0.92
2003 Beebe K, Merriman E, Schimmel P. Structure-specific tRNA determinants for editing a mischarged amino acid. The Journal of Biological Chemistry. 278: 45056-61. PMID 12949076 DOI: 10.1074/jbc.M307080200  0.92
2003 Beebe K, Ribas De Pouplana L, Schimmel P. Elucidation of tRNA-dependent editing by a class II tRNA synthetase and significance for cell viability. The Embo Journal. 22: 668-75. PMID 12554667 DOI: 10.1093/emboj/cdg065  0.92
2003 Bishop AC, Beebe K, Schimmel PR. Interstice mutations that block site-to-site translocation of a misactivated amino acid bound to a class I tRNA synthetase. Proceedings of the National Academy of Sciences of the United States of America. 100: 490-4. PMID 12515858 DOI: 10.1073/pnas.0237335100  0.92
2002 Arabaci G, Yi T, Fu H, Porter ME, Beebe KD, Pei D. alpha-bromoacetophenone derivatives as neutral protein tyrosine phosphatase inhibitors: structure-Activity relationship. Bioorganic & Medicinal Chemistry Letters. 12: 3047-50. PMID 12372498 DOI: 10.1016/S0960-894X(02)00681-9  0.92
2000 Beebe KD, Wang P, Arabaci G, Pei D. Determination of the binding specificity of the SH2 domains of protein tyrosine phosphatase SHP-1 through the screening of a combinatorial phosphotyrosyl peptide library. Biochemistry. 39: 13251-60. PMID 11052678 DOI: 10.1021/bi0014397  0.92
2000 Wang P, Byeon IJ, Liao H, Beebe KD, Yongkiettrakul S, Pei D, Tsai MD. II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides. Journal of Molecular Biology. 302: 927-40. PMID 10993733 DOI: 10.1006/jmbi.2000.4095  0.92
2000 Beebe KD, Shin J, Peng J, Chaudhury C, Khera J, Pei D. Substrate recognition through a PDZ domain in tail-specific protease. Biochemistry. 39: 3149-55. PMID 10715137 DOI: 10.1021/bi992709s  0.92
1999 Arabaci G, Guo XC, Beebe KD, Coggeshall KM, Pei D. α-haloacetophenone derivatives as photoreversible covalent inhibitors of protein tyrosine phosphatases Journal of the American Chemical Society. 121: 5085-5086. DOI: 10.1021/ja9906756  0.92
1998 Beebe KD, Pei D. A continuous fluorimetric assay for tail-specific protease. Analytical Biochemistry. 263: 51-6. PMID 9750142 DOI: 10.1006/abio.1998.2797  0.92
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