Amanda L. McClerren, Ph.D. - Publications

Affiliations: 
2005 Duke University, Durham, NC 
Area:
lipid biochemistry

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Thibodeaux GN, McClerren AL, Ma Y, Gancayco MR, Van Der Donk WA. Synergistic binding of the leader and core peptides by the lantibiotic synthetase HalM2 Acs Chemical Biology. 10: 970-977. DOI: 10.1021/cb5009876  0.72
2014 Leibman M, Shryock JJ, Clements MJ, Hall MA, Loida PJ, McClerren AL, McKiness ZP, Phillips JR, Rice EA, Stark SB. Comparative analysis of maize (Zea mays) crop performance: natural variation, incremental improvements and economic impacts. Plant Biotechnology Journal. 12: 941-50. PMID 24851925 DOI: 10.1111/Pbi.12202  0.72
2012 Qi Q, Gibson A, Fu X, Zheng M, Kuehn R, Wang Y, Wang Y, Navarro S, Morrell JA, Jiang D, Simmons G, Bell E, Ivleva NB, McClerren AL, Loida P, et al. Involvement of the N-terminal B-box domain of Arabidopsis BBX32 protein in interaction with soybean BBX62 protein. The Journal of Biological Chemistry. 287: 31482-93. PMID 22801428 DOI: 10.1074/Jbc.M112.346940  0.72
2012 Duff SM, Rydel TJ, McClerren AL, Zhang W, Li JY, Sturman EJ, Halls C, Chen S, Zeng J, Peng J, Kretzler CN, Evdokimov A. The enzymology of alanine aminotransferase (AlaAT) isoforms from Hordeum vulgare and other organisms, and the HvAlaAT crystal structure. Archives of Biochemistry and Biophysics. 528: 90-101. PMID 22750542 DOI: 10.1016/j.abb.2012.06.006  0.72
2012 Preuss SB, Meister R, Xu Q, Urwin CP, Tripodi FA, Screen SE, Anil VS, Zhu S, Morrell JA, Liu G, Ratcliffe OJ, Reuber TL, Khanna R, Goldman BS, Bell E, ... ... McClerren AL, et al. Expression of the Arabidopsis thaliana BBX32 gene in soybean increases grain yield. Plos One. 7: e30717. PMID 22363475 DOI: 10.1371/Journal.Pone.0030717  0.72
2009 Lee MV, Ihnken LA, You YO, McClerren AL, van der Donk WA, Kelleher NL. Distributive and directional behavior of lantibiotic synthetases revealed by high-resolution tandem mass spectrometry. Journal of the American Chemical Society. 131: 12258-64. PMID 19663480 DOI: 10.1021/Ja9033507  0.72
2008 Cooper LE, McClerren AL, Chary A, van der Donk WA. Structure-activity relationship studies of the two-component lantibiotic haloduracin. Chemistry & Biology. 15: 1035-45. PMID 18940665 DOI: 10.1016/J.Chembiol.2008.07.020  0.72
2007 Barb AW, McClerren AL, Snehelatha K, Reynolds CM, Zhou P, Raetz CR. Inhibition of lipid A biosynthesis as the primary mechanism of CHIR-090 antibiotic activity in Escherichia coli. Biochemistry. 46: 3793-802. PMID 17335290 DOI: 10.1021/Bi6025165  0.72
2006 McClerren AL, Cooper LE, Quan C, Thomas PM, Kelleher NL, van der Donk WA. Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic. Proceedings of the National Academy of Sciences of the United States of America. 103: 17243-8. PMID 17085596 DOI: 10.1073/Pnas.0606088103  0.72
2006 Mdluli KE, Witte PR, Kline T, Barb AW, Erwin AL, Mansfield BE, McClerren AL, Pirrung MC, Tumey LN, Warrener P, Raetz CR, Stover CK. Molecular validation of LpxC as an antibacterial drug target in Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy. 50: 2178-84. PMID 16723580 DOI: 10.1128/Aac.00140-06  0.72
2005 McClerren AL, Endsley S, Bowman JL, Andersen NH, Guan Z, Rudolph J, Raetz CR. A slow, tight-binding inhibitor of the zinc-dependent deacetylase LpxC of lipid A biosynthesis with antibiotic activity comparable to ciprofloxacin. Biochemistry. 44: 16574-83. PMID 16342948 DOI: 10.1021/Bi0518186  0.72
2005 Breazeale SD, Ribeiro AA, McClerren AL, Raetz CR. A formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-Amino-4-deoxy-L-arabinose. Identification and function oF UDP-4-deoxy-4-formamido-L-arabinose. The Journal of Biological Chemistry. 280: 14154-67. PMID 15695810 DOI: 10.1074/Jbc.M414265200  0.72
2005 Coggins BE, McClerren AL, Jiang L, Li X, Rudolph J, Hindsgaul O, Raetz CR, Zhou P. Refined solution structure of the LpxC-TU-514 complex and pKa analysis of an active site histidine: insights into the mechanism and inhibitor design. Biochemistry. 44: 1114-26. PMID 15667205 DOI: 10.1021/Bi047820Z  0.72
2005 McClerren AL, Zhou P, Guan Z, Raetz CR, Rudolph J. Kinetic analysis of the zinc-dependent deacetylase in the lipid A biosynthetic pathway. Biochemistry. 44: 1106-13. PMID 15667204 DOI: 10.1021/Bi048001H  0.72
2005 Li X, McClerren AL, Raetz CRH, Hindsgaul O. Mapping the active site of the bacterial enzyme LpxC using novel carbohydrate-based hydroxamic acid inhibitors Journal of Carbohydrate Chemistry. 24: 583-609. DOI: 10.1081/Car-200068781  0.72
2003 Coggins BE, Li X, McClerren AL, Hindsgaul O, Raetz CR, Zhou P. Structure of the LpxC deacetylase with a bound substrate-analog inhibitor. Nature Structural Biology. 10: 645-51. PMID 12833153 DOI: 10.1038/Nsb948  0.72
2003 Pirrung MC, Tumey LN, McClerren AL, Raetz CR. High-throughput catch-and-release synthesis of oxazoline hydroxamates. Structure-activity relationships in novel inhibitors of Escherichia coli LpxC: in vitro enzyme inhibition and antibacterial properties. Journal of the American Chemical Society. 125: 1575-86. PMID 12568618 DOI: 10.1021/Ja0209114  0.72
2002 Pirrung MC, Tumey LN, Raetz CR, Jackman JE, Snehalatha K, McClerren AL, Fierke CA, Gantt SL, Rusche KM. Inhibition of the antibacterial target UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC): isoxazoline zinc amidase inhibitors bearing diverse metal binding groups. Journal of Medicinal Chemistry. 45: 4359-70. PMID 12213077 DOI: 10.1021/Jm020183V  0.72
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