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Sean R. Marcsisin, Ph.D. - Publications

Affiliations: 
2011 Chemistry Northeastern University, Boston, MA, United States 
Area:
Bioanalytical chemistry, mass spectrometry, hydrogen/deuterium exchange
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16/27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kancharla P, Dodean RA, Li Y, Pou S, Pybus B, Melendez V, Read L, Bane CE, Vesely B, Kreishman-Deitrick M, Black C, Li Q, Sciotti RJ, Olmeda R, Luong TL, ... ... Marcsisin S, et al. Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials. Journal of Medicinal Chemistry. PMID 32390431 DOI: 10.1021/Acs.Jmedchem.0C00539  0.305
2019 Dodean RA, Kancharla P, Li Y, Melendez V, Read L, Bane C, Vesely B, Kreishman-Deitrick M, Black C, Li Q, Sciotti RJ, Olmeda R, Luong TL, Gaona H, Potter B, ... ... Marcsisin S, et al. Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials. Journal of Medicinal Chemistry. PMID 30852885 DOI: 10.1021/Acs.Jmedchem.8B01961  0.323
2017 Chaikuad A, Filippakopoulos P, Marcsisin SR, Picaud S, Schröder M, Sekine S, Ichijo H, Engen JR, Takeda K, Knapp S. Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly. Structure (London, England : 1993). PMID 28648608 DOI: 10.1016/J.Str.2017.05.020  0.497
2016 Milner EE, Berman J, Caridha D, Dickson SP, Hickman M, Lee PJ, Marcsisin SR, Read LT, Roncal N, Vesely BA, Xie LH, Zhang J, Zhang P, Li Q. Cytochrome P450 2D-mediated metabolism is not necessary for tafenoquine and primaquine to eradicate the erythrocytic stages of Plasmodium berghei. Malaria Journal. 15: 588. PMID 27923405 DOI: 10.1186/S12936-016-1632-8  0.321
2016 Jin X, Potter B, Luong TL, Nelson J, Vuong C, Potter C, Xie L, Zhang J, Zhang P, Sousa J, Li Q, Pybus BS, Kreishman-Deitrick M, Hickman M, Smith PL, ... ... Marcsisin SR, et al. Pre-clinical evaluation of CYP 2D6 dependent drug-drug interactions between primaquine and SSRI/SNRI antidepressants. Malaria Journal. 15: 280. PMID 27188854 DOI: 10.1186/S12936-016-1329-Z  0.337
2016 Marcsisin SR, Reichard G, Pybus BS. Primaquine pharmacology in the context of CYP 2D6 pharmacogenomics: Current state of the art. Pharmacology & Therapeutics. PMID 27016470 DOI: 10.1016/J.Pharmthera.2016.03.011  0.354
2015 Marcsisin SR, Liptak C, Marineau J, Bradner JE, Engen JR. Tag and Capture Flow Hydrogen Exchange Mass Spectrometry with a Fluorous-Immobilized Probe. Analytical Chemistry. 87: 6349-56. PMID 26023704 DOI: 10.1021/Acs.Analchem.5B01220  0.527
2015 Vuong C, Xie LH, Potter BM, Zhang J, Zhang P, Duan D, Nolan CK, Sciotti RJ, Zottig VE, Nanayakkara NP, Tekwani BL, Walker LA, Smith PL, Paris RM, Read LT, ... ... Marcsisin SR, et al. Differential Cytochrome P450 2D Metabolism Alters Tafenoquine Pharmacokinetics. Antimicrobial Agents and Chemotherapy. 59: 3864-9. PMID 25870069 DOI: 10.1128/Aac.00343-15  0.324
2015 Potter BM, Xie LH, Vuong C, Zhang J, Zhang P, Duan D, Luong TL, Bandara Herath HM, Dhammika Nanayakkara NP, Tekwani BL, Walker LA, Nolan CK, Sciotti RJ, Zottig VE, Smith PL, ... ... Marcsisin SR, et al. Differential CYP 2D6 metabolism alters primaquine pharmacokinetics. Antimicrobial Agents and Chemotherapy. 59: 2380-7. PMID 25645856 DOI: 10.1128/Aac.00015-15  0.322
2014 Fasinu PS, Tekwani BL, Nanayakkara NP, Avula B, Herath HM, Wang YH, Adelli VR, Elsohly MA, Khan SI, Khan IA, Pybus BS, Marcsisin SR, Reichard GA, McChesney JD, Walker LA. Enantioselective metabolism of primaquine by human CYP2D6. Malaria Journal. 13: 507. PMID 25518709 DOI: 10.1186/1475-2875-13-507  0.308
2014 Marcsisin SR, Sousa JC, Reichard GA, Caridha D, Zeng Q, Roncal N, McNulty R, Careagabarja J, Sciotti RJ, Bennett JW, Zottig VE, Deye G, Li Q, Read L, Hickman M, et al. Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds. Malaria Journal. 13: 2. PMID 24386891 DOI: 10.1186/1475-2875-13-2  0.329
2013 Marcsisin SR, Jin X, Bettger T, McCulley N, Sousa JC, Shanks GD, Tekwani BL, Sahu R, Reichard GA, Sciotti RJ, Melendez V, Pybus BS. CYP450 phenotyping and metabolite identification of quinine by accurate mass UPLC-MS analysis: a possible metabolic link to blackwater fever. Malaria Journal. 12: 214. PMID 23800033 DOI: 10.1186/1475-2875-12-214  0.348
2013 Pybus BS, Marcsisin SR, Jin X, Deye G, Sousa JC, Li Q, Caridha D, Zeng Q, Reichard GA, Ockenhouse C, Bennett J, Walker LA, Ohrt C, Melendez V. The metabolism of primaquine to its active metabolite is dependent on CYP 2D6. Malaria Journal. 12: 212. PMID 23782898 DOI: 10.1186/1475-2875-12-212  0.336
2011 Marcsisin SR, Narute PS, Emert-Sedlak LA, Kloczewiak M, Smithgall TE, Engen JR. On the solution conformation and dynamics of the HIV-1 viral infectivity factor. Journal of Molecular Biology. 410: 1008-22. PMID 21763503 DOI: 10.1016/J.Jmb.2011.04.053  0.53
2010 Marcsisin SR, Engen JR. Molecular insight into the conformational dynamics of the Elongin BC complex and its interaction with HIV-1 Vif. Journal of Molecular Biology. 402: 892-904. PMID 20728451 DOI: 10.1016/J.Jmb.2010.08.026  0.514
2010 Marcsisin SR, Engen JR. Hydrogen exchange mass spectrometry: what is it and what can it tell us? Analytical and Bioanalytical Chemistry. 397: 967-72. PMID 20195578 DOI: 10.1007/S00216-010-3556-4  0.517
Low-probability matches (unlikely to be authored by this person)
2014 Jin X, Luong TL, Reese N, Gaona H, Collazo-Velez V, Vuong C, Potter B, Sousa JC, Olmeda R, Li Q, Xie L, Zhang J, Zhang P, Reichard G, Melendez V, ... Marcsisin SR, et al. Comparison of MDCK-MDR1 and Caco-2 cell based permeability assays for anti-malarial drug screening and drug investigations. Journal of Pharmacological and Toxicological Methods. 70: 188-94. PMID 25150934 DOI: 10.1016/J.Vascn.2014.08.002  0.296
2016 Fasinu PS, Avula B, Tekwani BL, Nanayakkara NP, Wang YH, Bandara Herath HM, McChesney JD, Reichard GA, Marcsisin SR, Elsohly MA, Khan SI, Khan IA, Walker LA. Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytes. Malaria Journal. 15: 224. PMID 27093859 DOI: 10.1186/S12936-016-1270-1  0.288
2016 Wickham KS, Baresel PC, Marcsisin SR, Sousa J, Vuong CT, Reichard GA, Campo B, Tekwani BL, Walker LA, Rochford R. Single dose primaquine in a preclinical model of G6PD deficiency: implications for use in malaria transmission blocking programs. Antimicrobial Agents and Chemotherapy. PMID 27458212 DOI: 10.1128/Aac.00600-16  0.269
2017 Murphy SC, Duke ER, Shipman KJ, Jensen RL, Fong Y, Ferguson S, Janes HE, Gillespie K, Seilie AM, Hanron AE, Rinn L, Fishbaugher M, VonGoedert T, Fritzen E, Kappe SH, ... ... Marcsisin SR, et al. A randomized trial of the prophylactic activity of DSM265 against pre-erythrocytic Plasmodium falciparum controlled human malaria infection by mosquito bites and direct venous inoculation. The Journal of Infectious Diseases. PMID 29216395 DOI: 10.1093/Infdis/Jix613  0.267
2017 Li Q, Xie L, Caridha D, Zeng Q, Zhang J, Roncal N, Zhang P, Vuong C, Potter B, Sousa J, Marcsisin S, Read L, Hickman M. Long-Term Prophylaxis and Pharmacokinetic Evaluation of Intramuscular Nano- and Microparticle Decoquinate in Mice Infected with P. berghei Sporozoites. Malaria Research and Treatment. 2017: 7508291. PMID 28491482 DOI: 10.1155/2017/7508291  0.262
2017 Mountney A, Boutte A, Cartagena CM, Flerlage WJ, Johnson D, Rho C, Lu XM, Yarnell AM, Marcsisin SR, Sousa J, Vuong C, Zottig VE, Leung LY, Deng-Bryant Y, Gilsdorf J, et al. Functional and molecular correlates following single and repeated rat closed-head concussion; indices of vulnerability following brain injury. Journal of Neurotrauma. PMID 28326890 DOI: 10.1089/Neu.2016.4679  0.235
2017 Bookstaver DA, Sparks K, Pybus BS, Davis DK, Marcsisin SR, Sousa JC. Comparison of Anti-Xa Activity in Patients Receiving Apixaban or Rivaroxaban. The Annals of Pharmacotherapy. 1060028017738262. PMID 29047306 DOI: 10.1177/1060028017738262  0.23
2013 Mountney A, Shear DA, Potter B, Marcsisin SR, Sousa J, Melendez V, Tortella FC, Lu XC. Ethosuximide and phenytoin dose-dependently attenuate acute nonconvulsive seizures after traumatic brain injury in rats. Journal of Neurotrauma. 30: 1973-82. PMID 23822888 DOI: 10.1089/Neu.2013.3001  0.228
2019 Spring MD, Sousa JC, Li Q, Darko CA, Morrison MN, Marcsisin SR, Mills KT, Potter BM, Paolino KM, Twomey PS, Moon JE, Tosh DM, Cicatelli SB, Froude JW, Pybus BS, et al. Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population. The Journal of Infectious Diseases. PMID 31549155 DOI: 10.1093/infdis/jiz386  0.2
2018 Altman DE, Simmons LP, Vuong CT, Taylor RM, Sousa JC, Marcsisin SR, Zottig VE, Moore NLT. Developmental differences in stress responding after repeated underwater trauma exposures in rats. Stress (Amsterdam, Netherlands). 1-7. PMID 29451058 DOI: 10.1080/10253890.2018.1439012  0.192
2019 Spring MD, Sousa JC, Li Q, Darko CA, Morrison MN, Marcsisin SR, Mills KT, Potter BM, Paolino KM, Twomey PS, Moon JE, Tosh DM, Cicatelli SB, Froude JW, Pybus BS, et al. Corrigendum to: Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population. The Journal of Infectious Diseases. PMID 31773155 DOI: 10.1093/infdis/jiz599  0.168
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