Karen M. Wagner, Ph.D. - Publications

Affiliations: 
2012 Pharmacology and Toxicology University of California, Davis, Davis, CA 
Area:
Pesticide Biotechnology

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lee KSS, Yang J, Niu J, Ng CJ, Wagner KM, Dong H, Kodani SD, Wan D, Morisseau C, Hammock BD. Drug-Target Residence Time Affects Target Occupancy through Multiple Pathways. Acs Central Science. 5: 1614-1624. PMID 31572788 DOI: 10.1021/acscentsci.9b00770  0.64
2019 Wan D, Yang J, McReynolds CB, Barnych B, Wagner KM, Morisseau C, Hwang SH, Sun J, Blöcher R, Hammock BD. and Metabolism of a Potent Inhibitor of Soluble Epoxide Hydrolase, 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea. Frontiers in Pharmacology. 10: 464. PMID 31143115 DOI: 10.3389/fphar.2019.00464  0.64
2018 Hiesinger K, Wagner KM, Hammock BD, Proschak E, Hwang SH. Development of Multitarget Agents Possessing Soluble Epoxide Hydrolase Inhibitory Activity. Prostaglandins & Other Lipid Mediators. PMID 30593866 DOI: 10.1016/j.prostaglandins.2018.12.003  0.64
2018 Kodani SD, Wan D, Wagner KM, Hwang SH, Morisseau C, Hammock BD. Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors. Acs Omega. 3: 14076-14086. PMID 30411058 DOI: 10.1021/acsomega.8b01625  0.64
2018 Lee KSS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, et al. Correction to Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy. Journal of Medicinal Chemistry. PMID 29701466 DOI: 10.1021/acs.jmedchem.8b00582  0.64
2018 Blöcher R, Wagner KM, Gopireddy RR, Harris TR, Wu H, Barnych B, Hwang SH, Xiang YK, Proschak E, Morisseau C, Hammock BD. Orally available soluble epoxide hydrolase/phosphodiesterase 4 dual inhibitor treats inflammatory pain. Journal of Medicinal Chemistry. PMID 29614224 DOI: 10.1021/acs.jmedchem.7b01804  0.64
2017 Wagner KM, McReynolds CB, Schmidt WK, Hammock BD. Soluble epoxide hydrolase as a therapeutic target for pain, inflammatory and neurodegenerative diseases. Pharmacology & Therapeutics. PMID 28642117 DOI: 10.1016/j.pharmthera.2017.06.006  0.64
2016 Ren Q, Ma M, Ishima T, Morisseau C, Yang J, Wagner KM, Zhang JC, Yang C, Yao W, Dong C, Han M, Hammock BD, Hashimoto K. Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976569 DOI: 10.1073/pnas.1601532113  0.6
2015 Sasso O, Wagner K, Morisseau C, Inceoglu B, Hammock BD, Piomelli D. Peripheral FAAH and soluble epoxide hydrolase inhibitors are synergistically antinociceptive. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 97: 7-15. PMID 25882247 DOI: 10.1016/j.phrs.2015.04.001  0.6
2015 Haas MJ, Barr MR, Phillips J, Wagner KM. A Simple Standardization Method for the Biodiesel Cold Soak Filtration Apparatus Jaocs, Journal of the American Oil Chemists' Society. DOI: 10.1007/s11746-015-2695-3  0.6
2014 Wagner K, Vito S, Inceoglu B, Hammock BD. The role of long chain fatty acids and their epoxide metabolites in nociceptive signaling. Prostaglandins & Other Lipid Mediators. 113: 2-12. PMID 25240260 DOI: 10.1016/j.prostaglandins.2014.09.001  0.6
2014 Lee KS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, et al. Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. Journal of Medicinal Chemistry. 57: 7016-30. PMID 25079952 DOI: 10.1021/jm500694p  0.6
2014 Wagner K, Yang J, Inceoglu B, Hammock BD. Soluble epoxide hydrolase inhibition is antinociceptive in a mouse model of diabetic neuropathy. The Journal of Pain : Official Journal of the American Pain Society. 15: 907-14. PMID 24924124 DOI: 10.1016/j.jpain.2014.05.008  0.6
2013 Inceoglu B, Zolkowska D, Yoo HJ, Wagner KM, Yang J, Hackett E, Hwang SH, Lee KS, Rogawski MA, Morisseau C, Hammock BD. Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures. Plos One. 8: e80922. PMID 24349022 DOI: 10.1371/journal.pone.0080922  0.6
2013 Hwang SH, Wecksler AT, Wagner K, Hammock BD. Rationally designed multitarget agents against inflammation and pain. Current Medicinal Chemistry. 20: 1783-99. PMID 23410172 DOI: 10.2174/0929867311320130013  0.6
2013 Wagner K, Inceoglu B, Dong H, Yang J, Hwang SH, Jones P, Morisseau C, Hammock BD. Comparative efficacy of 3 soluble epoxide hydrolase inhibitors in rat neuropathic and inflammatory pain models. European Journal of Pharmacology. 700: 93-101. PMID 23276668 DOI: 10.1016/j.ejphar.2012.12.015  0.6
2012 Inceoglu B, Wagner KM, Yang J, Bettaieb A, Schebb NH, Hwang SH, Morisseau C, Haj FG, Hammock BD. Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of type I diabetes. Proceedings of the National Academy of Sciences of the United States of America. 109: 11390-5. PMID 22733772 DOI: 10.1073/pnas.1208708109  0.6
2011 Wagner K, Inceoglu B, Hammock BD. Soluble epoxide hydrolase inhibition, epoxygenated fatty acids and nociception Prostaglandins and Other Lipid Mediators. 96: 76-83. PMID 21854866 DOI: 10.1016/j.prostaglandins.2011.08.001  0.6
2011 Schebb NH, Inceoglu B, Rose T, Wagner K, Hammock BD. Development of an ultra fast online-solid phase extraction (SPE) liquid chromatography electrospray tandem mass spectrometry (LC-ESI-MS/MS) based approach for the determination of drugs in pharmacokinetic studies. Analytical Methods : Advancing Methods and Applications. 3: 420-428. PMID 21660124 DOI: 10.1039/C0AY00714E  0.6
2011 Hwang SH, Wagner KM, Morisseau C, Liu JY, Dong H, Wecksler AT, Hammock BD. Synthesis and structure-activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolase. Journal of Medicinal Chemistry. 54: 3037-50. PMID 21434686 DOI: 10.1021/jm2001376  0.6
2011 Inceoglu B, Wagner K, Schebb NH, Morisseau C, Jinks SL, Ulu A, Hegedus C, Rose T, Brosnan R, Hammock BD. Analgesia mediated by soluble epoxide hydrolase inhibitors is dependent on cAMP. Proceedings of the National Academy of Sciences of the United States of America. 108: 5093-7. PMID 21383170 DOI: 10.1073/pnas.1101073108  0.6
2011 Wagner K, Inceoglu B, Gill SS, Hammock BD. Epoxygenated fatty acids and soluble epoxide hydrolase inhibition: novel mediators of pain reduction. Journal of Agricultural and Food Chemistry. 59: 2816-24. PMID 20958046 DOI: 10.1021/jf102559q  0.6
2011 Haas MJ, Wagner KM. Substrate pretreatment can reduce the alcohol requirement during biodiesel production via in situ transesterification Jaocs, Journal of the American Oil Chemists' Society. 88: 1203-1209. DOI: 10.1007/s11746-011-1773-4  0.6
2011 Haas MJ, Wagner K. Simplifying biodiesel production: The direct or in situ transesterification of algal biomass European Journal of Lipid Science and Technology. 113: 1219-1229. DOI: 10.1002/ejlt.201100106  0.6
2008 Inceoglu B, Jinks SL, Ulu A, Hegedus CM, Georgi K, Schmelzer KR, Wagner K, Jones PD, Morisseau C, Hammock BD. Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 18901-6. PMID 19028872 DOI: 10.1073/pnas.0809765105  0.6
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