Kyu-Yeon Jun, Ph.D. - Publications

Affiliations: 
2006 University of Houston, Houston, TX, United States 
Area:
Biological NMR of Nucleic Acids and Proteins; Microarray BIOCHIP Technologies

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Arepalli SK, Lee C, Sim S, Lee K, Jo H, Jun KY, Kwon Y, Kang JS, Jung JK, Lee H. Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors. Bioorganic & Medicinal Chemistry. PMID 30253887 DOI: 10.1016/j.bmc.2018.09.019  0.8
2018 Bae HD, Lee J, Jun KY, Kwon Y, Lee K. Modification of translationally controlled tumor protein-derived protein transduction domain for improved intranasal delivery of insulin. Drug Delivery. 25: 1025-1032. PMID 29688087 DOI: 10.1080/10717544.2018.1464081  0.8
2017 Arepalli SK, Park B, Lee K, Jo H, Jun KY, Kwon Y, Kang JS, Jung JK, Lee H. Design, synthesis and biological evaluation of 1,3-diphenylbenzo[f][1,7]naphthyrdines. Bioorganic & Medicinal Chemistry. PMID 28870801 DOI: 10.1016/j.bmc.2017.08.030  0.8
2016 Park S, Kadayat TM, Jun KY, Thapa Magar TB, Bist G, Shrestha A, Lee ES, Kwon Y. Novel 2-aryl-4-(4'-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors. European Journal of Medicinal Chemistry. 125: 14-28. PMID 27643560 DOI: 10.1016/j.ejmech.2016.09.019  0.8
2016 Jun KY, Kwon Y. Proposal of Dual Inhibitor Targeting ATPase Domains of Topoisomerase II and Heat Shock Protein 90. Biomolecules & Therapeutics. 24: 453-68. PMID 27582553 DOI: 10.4062/biomolther.2016.168  0.8
2016 Park S, Hong E, Kwak SY, Jun KY, Lee ES, Kwon Y, Na Y. Synthesis and biological evaluation of C1-O-substituted-3-(3-butylamino-2-hydroxy-propoxy)-xanthen-9-one as topoisomerase IIα catalytic inhibitors. European Journal of Medicinal Chemistry. 123: 211-225. PMID 27484510 DOI: 10.1016/j.ejmech.2016.07.046  0.8
2016 Jeon KH, Lee E, Jun KY, Eom JE, Kwak SY, Na Y, Kwon Y. Neuroprotective effect of synthetic chalcone derivatives as competitive dual inhibitors against μ-calpain and cathepsin B through the downregulation of tau phosphorylation and insoluble Aβ peptide formation. European Journal of Medicinal Chemistry. 121: 433-444. PMID 27318120 DOI: 10.1016/j.ejmech.2016.06.008  0.8
2016 Ahmad P, Woo H, Jun KY, Kadi AA, Abdel-Aziz HA, Kwon Y, Rahman AF. Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure-activity relationship study of pyrazoline derivatives: An ATP-competitive human topoisomerase IIα catalytic inhibitor. Bioorganic & Medicinal Chemistry. PMID 26988802 DOI: 10.1016/j.bmc.2016.03.017  0.8
2016 Karki R, Jun KY, Kadayat TM, Shin S, Thapa Magar TB, Bist G, Shrestha A, Na Y, Kwon Y, Lee ES. A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study. European Journal of Medicinal Chemistry. 113: 228-245. PMID 26945111 DOI: 10.1016/j.ejmech.2016.02.050  0.8
2016 Kadayat TM, Park S, Jun KY, Magar TB, Bist G, Shrestha A, Na Y, Kwon Y, Lee ES. Effect of chlorine substituent on cytotoxic activities: Design and synthesis of systematically modified 2,4-diphenyl-5H-indeno[1,2-b]pyridines. Bioorganic & Medicinal Chemistry Letters. PMID 26927425 DOI: 10.1016/j.bmcl.2016.02.053  0.8
2015 Thapa P, Jun KY, Kadayat TM, Park C, Zheng Z, Thapa Magar TB, Bist G, Shrestha A, Na Y, Kwon Y, Lee ES. Design and synthesis of conformationally constrained hydroxylated 4-phenyl-2-aryl chromenopyridines as novel and selective topoisomerase II-targeted antiproliferative agents. Bioorganic & Medicinal Chemistry. PMID 26361737 DOI: 10.1016/j.bmc.2015.08.018  0.8
2015 Jun KY, Park SE, Liang JL, Jahng Y, Kwon Y. Benzo[b]tryptanthrin inhibits MDR1, topoisomerase activity, and reverses adriamycin resistance in breast cancer cells. Chemmedchem. 10: 827-35. PMID 25809558 DOI: 10.1002/cmdc.201500068  0.8
2015 Kwon HB, Park C, Jeon KH, Lee E, Park SE, Jun KY, Kadayat TM, Thapa P, Karki R, Na Y, Park MS, Rho SB, Lee ES, Kwon Y. A series of novel terpyridine-skeleton molecule derivants inhibit tumor growth and metastasis by targeting topoisomerases. Journal of Medicinal Chemistry. 58: 1100-22. PMID 25603122 DOI: 10.1021/jm501023q  0.8
2015 Kadayat TM, Park C, Jun KY, Magar TB, Bist G, Yoo HY, Kwon Y, Lee ES. Design and synthesis of novel 2,4-diaryl-5H-indeno[1,2-b]pyridine derivatives, and their evaluation of topoisomerase inhibitory activity and cytotoxicity. Bioorganic & Medicinal Chemistry. 23: 160-73. PMID 25481396 DOI: 10.1016/j.bmc.2014.11.010  0.8
2015 Karki R, Park C, Jun KY, Kadayat TM, Lee ES, Kwon Y. Synthesis and biological activity of 2,4-di-p-phenolyl-6-2-furanyl-pyridine as a potent topoisomerase II poison. European Journal of Medicinal Chemistry. 90: 360-78. PMID 25437622 DOI: 10.1016/j.ejmech.2014.11.045  0.8
2015 Kadayat TM, Park C, Jun KY, Thapa Magar TB, Bist G, Yoo HY, Kwon Y, Lee ES. Hydroxylated 2,4-diphenyl indenopyridine derivatives as a selective non-intercalative topoisomerase IIα catalytic inhibitor. European Journal of Medicinal Chemistry. 90: 302-14. PMID 25437617 DOI: 10.1016/j.ejmech.2014.11.046  0.8
2014 Jin CH, Jun KY, Lee E, Kim S, Kwon Y, Kim K, Na Y. Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. Bioorganic & Medicinal Chemistry. 22: 4553-65. PMID 25131958 DOI: 10.1016/j.bmc.2014.07.037  0.8
2014 Karki R, Park C, Jun KY, Jee JG, Lee JH, Thapa P, Kadayat TM, Kwon Y, Lee ES. Synthesis, antitumor activity, and structure-activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitors. European Journal of Medicinal Chemistry. 84: 555-65. PMID 25062006 DOI: 10.1016/j.ejmech.2014.07.058  0.8
2014 Jun KY, Kwon H, Park SE, Lee E, Karki R, Thapa P, Lee JH, Lee ES, Kwon Y. Discovery of dihydroxylated 2,4-diphenyl-6-thiophen-2-yl-pyridine as a non-intercalative DNA-binding topoisomerase II-specific catalytic inhibitor. European Journal of Medicinal Chemistry. 80: 428-38. PMID 24796883 DOI: 10.1016/j.ejmech.2014.04.066  0.8
2013 Park SE, Chang IH, Jun KY, Lee E, Lee ES, Na Y, Kwon Y. 3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage. European Journal of Medicinal Chemistry. 69: 139-45. PMID 24013413 DOI: 10.1016/j.ejmech.2013.07.048  0.8
2013 Nam JM, Jeon KH, Kwon H, Lee E, Jun KY, Jin YB, Lee YS, Na Y, Kwon Y. Dithiiranylmethyloxy azaxanthone shows potent anti-tumor activity via suppression of HER2 expression and HER2-mediated signals in HER2-overexpressing breast cancer cells. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 50: 181-90. PMID 23835029 DOI: 10.1016/j.ejps.2013.06.014  0.8
2013 Jeon KH, Jun KY, Kim EY, Kwon Y. Expression and purification of a soluble ESX-binding core domain of SUR2. Preparative Biochemistry & Biotechnology. 43: 364-75. PMID 23464919 DOI: 10.1080/10826068.2012.738273  0.8
2013 Lee E, Eom JE, Kim HL, Baek KH, Jun KY, Kim HJ, Lee M, Mook-Jung I, Kwon Y. Effect of conjugated linoleic acid, μ-calpain inhibitor, on pathogenesis of Alzheimer's disease. Biochimica Et Biophysica Acta. 1831: 709-18. PMID 23246577 DOI: 10.1016/j.bbalip.2012.12.003  0.8
2012 Kim HL, Jeon KH, Jun KY, Choi Y, Kim DK, Na Y, Kwon Y. A-62176, a potent topoisomerase inhibitor, inhibits the expression of human epidermal growth factor receptor 2. Cancer Letters. 325: 72-9. PMID 22732416 DOI: 10.1016/j.canlet.2012.06.004  0.8
2012 Lee E, Eom JE, Kim HL, Kang DH, Jun KY, Jung DS, Kwon Y. Neuroprotective effect of undecylenic acid extracted from Ricinus communis L. through inhibition of μ-calpain. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 46: 17-25. PMID 22333440 DOI: 10.1016/j.ejps.2012.01.015  0.8
2011 Jun KY, Lee EY, Jung MJ, Lee OH, Lee ES, Park Choo HY, Na Y, Kwon Y. Synthesis, biological evaluation, and molecular docking study of 3-(3'-heteroatom substituted-2'-hydroxy-1'-propyloxy) xanthone analogues as novel topoisomerase IIα catalytic inhibitor. European Journal of Medicinal Chemistry. 46: 1964-71. PMID 21419530 DOI: 10.1016/j.ejmech.2011.01.011  0.8
2010 Xia Y, Zhu Q, Jun KY, Wang J, Gao X. Clean STD-NMR spectrum for improved detection of ligand-protein interactions at low concentration of protein. Magnetic Resonance in Chemistry : Mrc. 48: 918-24. PMID 20957656 DOI: 10.1002/mrc.2687  0.8
2010 Choi Y, Jeon S, Choi M, Lee MH, Park M, Lee DR, Jun KY, Kwon Y, Lee OH, Song SH, Kim JY, Lee KA, Yoon TK, Rajkovic A, Shim SH. Mutations in SOHLH1 gene associate with nonobstructive azoospermia. Human Mutation. 31: 788-93. PMID 20506135 DOI: 10.1002/humu.21264  0.8
2009 Kang DH, Jun KY, Lee JP, Pak CS, Na Y, Kwon Y. Identification of 3-acetyl-2-aminoquinolin-4-one as a novel, nonpeptidic scaffold for specific calpain inhibitory activity. Journal of Medicinal Chemistry. 52: 3093-7. PMID 19419206 DOI: 10.1021/jm8014734  0.8
2008 Hashem MA, Jun KY, Lee E, Lim S, Choo HY, Kwon Y. A rapid and sensitive screening system for human type I collagen with the aim of discovering potent anti-aging or anti-fibrotic compounds. Molecules and Cells. 26: 625-30. PMID 18810249  0.8
2008 Rahman AFMM, Dong HK, Jing LL, Lee ES, Na Y, Jun KY, Kwon Y, Jahng Y. Synthesis and Biological Properties of Luotonin a Derivatives Bulletin of the Korean Chemical Society. 29: 1988-1992.  0.8
2007 Zhu Q, Hong A, Sheng N, Zhang X, Matejko A, Jun KY, Srivannavit O, Gulari E, Gao X, Zhou X. microParaflo biochip for nucleic acid and protein analysis. Methods in Molecular Biology (Clifton, N.J.). 382: 287-312. PMID 18220239  0.8
2005 Xia Y, Legge G, Jun KY, Qi Y, Lee H, Gao X. IP-COSY, a totally in-phase and sensitive COSY experiment. Magnetic Resonance in Chemistry : Mrc. 43: 372-9. PMID 15706609 DOI: 10.1002/mrc.1558  0.8
2004 Jun KY, Xia Y, Han X, Zhang H, Timchenko L, Swanson MS, Gao X. (1)H, (15)N and (13)C chemical shift assignments of RNA repeats binding protein -- CUGBP1ab. Journal of Biomolecular Nmr. 30: 371-2. PMID 15756469 DOI: 10.1007/s10858-005-2598-y  0.8
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