| Year |
Citation |
Score |
| 2022 |
Ma H, Brust T, Frankowski KJ, Lovell KM, Cameron MD, Bohn LM, Aubé J. Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural Refinement and Evaluation of CNS Clearance. Acs Chemical Neuroscience. 13: 1315-1332. PMID 35410469 DOI: 10.1021/acschemneuro.2c00140 |
0.706 |
|
| 2018 |
Kennedy NM, Schmid CL, Ross NC, Lovell KM, Yue Z, Chen YT, Cameron MD, Bohn LM, Bannister TD. Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias. Journal of Medicinal Chemistry. PMID 30199635 DOI: 10.1021/Acs.Jmedchem.8B01136 |
0.83 |
|
| 2017 |
Schmid CL, Kennedy NM, Ross NC, Lovell KM, Yue Z, Morgenweck J, Cameron MD, Bannister TD, Bohn LM. Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics. Cell. 171: 1165-1175.e13. PMID 29149605 DOI: 10.1016/J.Cell.2017.10.035 |
0.828 |
|
| 2017 |
Lovell KM, Frankowski KJ, Stahl EL, Slauson SR, Yoo E, Prisinzano TE, Aubé J, Bohn LM. Correction to "Structure-Activity Relationship Studies of Functionally Selective Kappa Opioid Receptor Agonists that Modulate ERK 1/2 Phosphorylation While Preserving G Protein Over βArrestin2 Signaling Bias". Acs Chemical Neuroscience. PMID 28541028 DOI: 10.1021/acschemneuro.7b00157 |
0.791 |
|
| 2016 |
Scarry SM, Lovell KM, Frankowski KJ, Bohn LM, Aubé J. Synthesis of Kappa Opioid Antagonists Based On Pyrrolo[1,2-alpha]quinoxalinones Using an N-Arylation/Condensation/Oxidation Reaction Sequence. The Journal of Organic Chemistry. PMID 27399050 DOI: 10.1021/Acs.Joc.6B01350 |
0.711 |
|
| 2015 |
Zhou L, Stahl EL, Lovell KM, Frankowski KJ, Prisinzano TE, Aubé J, Bohn LM. Characterization of kappa opioid receptor mediated, dynorphin-stimulated [(35)S]GTPγS binding in mouse striatum for the evaluation of selective KOR ligands in an endogenous setting. Neuropharmacology. PMID 26160155 DOI: 10.1016/J.Neuropharm.2015.07.001 |
0.808 |
|
| 2015 |
Lovell KM, Frankowski KJ, Stahl EL, Slauson SR, Yoo E, Prisinzano TE, Aubé J, Bohn LM. Structure-Activity Relationship Studies of Functionally Selective Kappa Opioid Receptor Agonists that Modulate ERK 1/2 Phosphorylation While Preserving G Protein Over βArrestin2 Signaling Bias. Acs Chemical Neuroscience. PMID 25891774 DOI: 10.1021/Acschemneuro.5B00092 |
0.777 |
|
| 2015 |
Frankowski KJ, Slauson SR, Lovell KM, Phillips AM, Streicher JM, Zhou L, Whipple DA, Schoenen FJ, Prisinzano TE, Bohn LM, Aubé J. Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. Bioorganic & Medicinal Chemistry. 23: 3948-56. PMID 25593096 DOI: 10.1016/J.Bmc.2014.12.033 |
0.805 |
|
| 2013 |
Caspers MJ, Williams TD, Lovell KM, Lozama A, Butelman ER, Kreek MJ, Johnson M, Griffiths R, Maclean K, Prisinzano TE. LC-MS/MS quantification of salvinorin A from biological fluids. Analytical Methods : Advancing Methods and Applications. 5. PMID 24416081 DOI: 10.1039/C3Ay40810H |
0.733 |
|
| 2013 |
Zhou L, Lovell KM, Frankowski KJ, Slauson SR, Phillips AM, Streicher JM, Stahl E, Schmid CL, Hodder P, Madoux F, Cameron MD, Prisinzano TE, Aubé J, Bohn LM. Development of functionally selective, small molecule agonists at kappa opioid receptors. The Journal of Biological Chemistry. 288: 36703-16. PMID 24187130 DOI: 10.1074/Jbc.M113.504381 |
0.812 |
|
| 2012 |
Lovell KM, Vasiljevik T, Araya JJ, Lozama A, Prevatt-Smith KM, Day VW, Dersch CM, Rothman RB, Butelman ER, Kreek MJ, Prisinzano TE. Semisynthetic neoclerodanes as kappa opioid receptor probes. Bioorganic & Medicinal Chemistry. 20: 3100-10. PMID 22464684 DOI: 10.1016/J.Bmc.2012.02.040 |
0.742 |
|
| 2012 |
Butelman ER, Caspers M, Lovell KM, Kreek MJ, Prisinzano TE. Behavioral effects and central nervous system levels of the broadly available κ-agonist hallucinogen salvinorin A are affected by P-glycoprotein modulation in vivo. The Journal of Pharmacology and Experimental Therapeutics. 341: 802-8. PMID 22434677 DOI: 10.1124/Jpet.112.193227 |
0.596 |
|
| 2011 |
Prevatt-Smith KM, Lovell KM, Simpson DS, Day VW, Douglas JT, Bosch P, Dersch CM, Rothman RB, Kivell B, Prisinzano TE. Potential Drug Abuse Therapeutics Derived from the Hallucinogenic Natural Product Salvinorin A. Medchemcomm. 2: 1217-1222. PMID 22442751 DOI: 10.1039/C1Md00192B |
0.786 |
|
| 2011 |
Lovell KM, Prevatt-Smith KM, Lozama A, Prisinzano TE. Synthesis of neoclerodane diterpenes and their pharmacological effects. Topics in Current Chemistry. 299: 141-85. PMID 21630517 DOI: 10.1007/128_2010_82 |
0.727 |
|
| 2010 |
Drinkwater N, Vu H, Lovell KM, Criscione KR, Collins BM, Prisinzano TE, Poulsen SA, McLeish MJ, Grunewald GL, Martin JL. Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors. The Biochemical Journal. 431: 51-61. PMID 20642456 DOI: 10.1042/Bj20100651 |
0.561 |
|
| 2009 |
Lovell KM, Simpson DS, Cunningham CW, Prisinzano TE. Utilizing nature as a source of new probes for opioid pharmacology. Future Medicinal Chemistry. 1: 285-301. PMID 21425970 DOI: 10.4155/Fmc.09.22 |
0.811 |
|
| 2009 |
Simpson DS, Lovell KM, Lozama A, Han N, Day VW, Dersch CM, Rothman RB, Prisinzano TE. Synthetic studies of neoclerodane diterpenes from Salvia divinorum: role of the furan in affinity for opioid receptors. Organic & Biomolecular Chemistry. 7: 3748-56. PMID 19707679 DOI: 10.1039/B905148A |
0.834 |
|
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