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Karen M. Bussard, Ph.D. - Publications

Affiliations: 
2008 Pennsylvania State University, State College, PA, United States 
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35/44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Shupp AB, Neupane M, Agostini LC, Ning G, Brody JR, Bussard KM. Stromal-derived extracellular vesicles suppress proliferation of bone metastatic cancer cells mediated by ERK2. Molecular Cancer Research : McR. PMID 34021072 DOI: 10.1158/1541-7786.MCR-20-0981  0.704
2021 Bussard KM, Gigliotti CM, Adair BM, Snyder JM, Gigliotti NT, Loc WS, Wilczynski ZR, Liu ZK, Meisel K, Zemanek C, Mastro AM, Shupp AB, McGovern C, Matters GL, Adair JH. Preferential uptake of antibody targeted calcium Phosphosilicate nanoparticles by metastatic triple negative breast Cancer cells in co-cultures of human metastatic breast Cancer cells plus bone osteoblasts. Nanomedicine : Nanotechnology, Biology, and Medicine. 102383. PMID 33722692 DOI: 10.1016/j.nano.2021.102383  0.725
2021 Dai J, Shupp AB, Bussard KM, Keller ET. Extracellular Vesicles and Bone-Associated Cancer. Current Osteoporosis Reports. PMID 33638774 DOI: 10.1007/s11914-021-00668-w  0.563
2021 Hughes AM, Kolb AD, Shupp AB, Shine KM, Bussard KM. Printing the Pathway Forward in Bone Metastatic Cancer Research: Applications of 3D Engineered Models and Bioprinted Scaffolds to Recapitulate the Bone-Tumor Niche. Cancers. 13. PMID 33572757 DOI: 10.3390/cancers13030507  0.613
2021 Kolb AD, Dai J, Keller ET, Bussard KM. 'Educated' Osteoblasts Reduce Osteoclastogenesis in a Bone-Tumor Mimetic Microenvironment. Cancers. 13. PMID 33445695 DOI: 10.3390/cancers13020263  0.532
2020 Shupp AB, Kolb AD, Bussard KM. Novel Techniques to Study the Bone-Tumor Microenvironment. Advances in Experimental Medicine and Biology. 1225: 1-18. PMID 32030644 DOI: 10.1007/978-3-030-35727-6_1  0.733
2020 Kolb AD, Bussard KM. Abstract 3993: 'Educated' osteoblasts suppress osteoclastogenesis and bone resorption in a bone mimetic microenvironment Tumor Biology. DOI: 10.1158/1538-7445.Am2020-3993  0.518
2020 Shupp AB, Bussard KM. Abstract 3976: Tumor-educated osteoblasts regulate breast cancer cell proliferation via extracellular vesicles Tumor Biology. DOI: 10.1158/1538-7445.Am2020-3976  0.598
2019 Kolb AD, Bussard KM. The Bone Extracellular Matrix as an Ideal Milieu for Cancer Cell Metastases. Cancers. 11. PMID 31330786 DOI: 10.3390/Cancers11071020  0.686
2019 Kolb AD, Shupp AB, Mukhopadhyay D, Marini FC, Bussard KM. Osteoblasts are "educated" by crosstalk with metastatic breast cancer cells in the bone tumor microenvironment. Breast Cancer Research : Bcr. 21: 31. PMID 30813947 DOI: 10.1186/S13058-019-1117-0  0.726
2019 Bussard K, Shupp A, Kolb A, Mukhopdhyay D. Abstract GS1-03: Crosstalk between osteoblasts and breast cancer cells alters breast cancer proliferation through multiple mechanisms Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Gs1-03  0.736
2019 Kolb AD, Shupp AB, Mukhopdhyay D, Bussard KM. Abstract 2036: Osteoblasts use multiple mechanisms of cellular communication to regulate breast cancer cell proliferation in bone Cancer Research. 79: 2036-2036. DOI: 10.1158/1538-7445.Am2019-2036  0.724
2018 Shupp AB, Kolb AD, Mukhopadhyay D, Bussard KM. Cancer Metastases to Bone: Concepts, Mechanisms, and Interactions with Bone Osteoblasts. Cancers. 10. PMID 29867053 DOI: 10.3390/Cancers10060182  0.757
2018 Wang KR, Abraham JA, McCue P, Schiewer MJ, Bussard KM, Fatatis A, Languino L, Leiby B, O'Neill R, Li J, Richter BI, Kelly WK. Characterization of a bone biorepository: Comparison of bone metastases from breast, prostate, renal, lung cancers, and myeloma. Journal of Clinical Oncology. 36: e24019-e24019. DOI: 10.1200/Jco.2018.36.15_Suppl.E24019  0.668
2017 Bussard KM, Siracusa LD. Understanding Mitochondrial Polymorphisms in Cancer. Cancer Research. PMID 29097610 DOI: 10.1158/0008-5472.Can-17-1939  0.415
2017 Marini F, Chifman J, Tooze J, Gomez-Manzano C, Bussard KM. Abstract 5890: Osteoblasts are educated into a tumor-associated stromal cell by disseminated breast cancer cells and mediate breast cancer cell proliferation in the bone microenvironment Cancer Research. 77: 5890-5890. DOI: 10.1158/1538-7445.Am2017-5890  0.745
2016 Siracusa LD, Bussard KM. The Clock Is Ticking: Countdown to Metastases. Plos Genetics. 12: e1006299. PMID 27657702 DOI: 10.1371/Journal.Pgen.1006299  0.446
2016 Bussard KM, Mutkus L, Stumpf K, Gomez-Manzano C, Marini FC. Tumor-associated stromal cells as key contributors to the tumor microenvironment. Breast Cancer Research : Bcr. 18: 84. PMID 27515302 DOI: 10.1186/S13058-016-0740-2  0.429
2016 Bussard KM, Marini FC. Abstract 1556: Tumor-associated osteoblasts are major mediators in facilitating bone metastatic breast cancer cell quiescence Cancer Research. 76: 1556-1556. DOI: 10.1158/1538-7445.Am2016-1556  0.605
2015 Bussard KM, Marini FC. Abstract 3205: Breast cancer cell quiescence in bone is modulated by Osteo-TAFs Cancer Research. 75: 3205-3205. DOI: 10.1158/1538-7445.Am2015-3205  0.601
2014 Bussard KM, Marini FC. Abstract 4804: Metastatic breast cancer cells induce an osteoblast-TAF-like phenotype and communicate with osteoblasts via gap junctions and exosomal crosstalk to facilitate breast cancer cell quiescence in bone Cancer Research. 74: 4804-4804. DOI: 10.1158/1538-7445.Am2014-4804  0.689
2014 Leahey KE, Welch DR, Chen Y, Bussard KM, Mastro AM. Abstract 130: Deadly KISS, Kisspeptin10 interaction with osteoblasts and breast cancer metastastic cells Cancer Research. 74: 130-130. DOI: 10.1158/1538-7445.Am2014-130  0.816
2014 Mastro AM, Sosnoski DM, Krishnan V, Bussard KM. The influence of metastatic breast cancer on the bone microenvironment Signaling Pathways and Molecular Mediators in Metastasis. 347-368. DOI: 10.1007/978-94-007-2558-4_15  0.813
2013 Bussard KM, Marini FC. Abstract 1625: Crosstalk between breast cancer and stromal cells occurs via exosomes and gap junctions in bone metastatic breast cancer. Cancer Research. 73: 1625-1625. DOI: 10.1158/1538-7445.Am2013-1625  0.778
2012 Bussard KM, Smith GH. Human breast cancer cells are redirected to mammary epithelial cells upon interaction with the regenerating mammary gland microenvironment in-vivo. Plos One. 7: e49221. PMID 23155468 DOI: 10.1371/Journal.Pone.0049221  0.633
2011 Bussard KM, Smith GH. The mammary gland microenvironment directs progenitor cell fate in vivo. International Journal of Cell Biology. 2011: 451676. PMID 21647291 DOI: 10.1155/2011/451676  0.39
2011 Bussard KM, Smith G. Abstract 434: Human breast cancer cells are reprogrammed to a non-tumorigenic/non-metastatic cell fate in vivo Cancer Research. 71: 434-434. DOI: 10.1158/1538-7445.Am2011-434  0.662
2010 Bussard KM, Venzon DJ, Mastro AM. Osteoblasts are a major source of inflammatory cytokines in the tumor microenvironment of bone metastatic breast cancer. Journal of Cellular Biochemistry. 111: 1138-48. PMID 20683902 DOI: 10.1002/Jcb.22799  0.829
2010 Bussard KM, Boulanger CA, Booth BW, Bruno RD, Smith GH. Reprogramming human cancer cells in the mouse mammary gland. Cancer Research. 70: 6336-43. PMID 20647316 DOI: 10.1158/0008-5472.Can-10-0591  0.461
2010 Bussard KM, Okita N, Sharkey N, Neuberger T, Webb A, Mastro AM. Localization of osteoblast inflammatory cytokines MCP-1 and VEGF to the matrix of the trabecula of the femur, a target area for metastatic breast cancer cell colonization. Clinical & Experimental Metastasis. 27: 331-40. PMID 20446021 DOI: 10.1007/S10585-010-9330-3  0.811
2010 Bussard KM, Boulanger CA, Smith GH. Abstract 1011: Cues from the tissue microenvironment redirect cancer cell fate in vivo Cancer Research. 70: 1011-1011. DOI: 10.1158/1538-7445.Am10-1011  0.546
2009 Bussard KM, Mastro AM. Ex-vivo analysis of the bone microenvironment in bone metastatic breast cancer. Journal of Mammary Gland Biology and Neoplasia. 14: 387-95. PMID 19949843 DOI: 10.1007/S10911-009-9159-Z  0.815
2008 Bussard KM, Gay CV, Mastro AM. The bone microenvironment in metastasis; what is special about bone? Cancer Metastasis Reviews. 27: 41-55. PMID 18071636 DOI: 10.1007/S10555-007-9109-4  0.769
2008 Kinder M, Chislock E, Bussard KM, Shuman L, Mastro AM. Metastatic breast cancer induces an osteoblast inflammatory response. Experimental Cell Research. 314: 173-83. PMID 17976581 DOI: 10.1016/J.Yexcr.2007.09.021  0.7
2006 Phadke PA, Mercer RR, Harms JF, Jia Y, Frost AR, Jewell JL, Bussard KM, Nelson S, Moore C, Kappes JC, Gay CV, Mastro AM, Welch DR. Kinetics of metastatic breast cancer cell trafficking in bone. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 1431-40. PMID 16533765 DOI: 10.1158/1078-0432.Ccr-05-1806  0.774
Low-probability matches (unlikely to be authored by this person)
2010 Bussard KM, Boulanger CA, Kittrell FS, Behbod F, Medina D, Smith GH. Immortalized, pre-malignant epithelial cell populations contain long-lived, label-retaining cells that asymmetrically divide and retain their template DNA. Breast Cancer Research : Bcr. 12: R86. PMID 20964820 DOI: 10.1186/Bcr2754  0.286
2005 Zhuo R, Miller R, Bussard KM, Siedlecki CA, Vogler EA. Procoagulant stimulus processing by the intrinsic pathway of blood plasma coagulation. Biomaterials. 26: 2965-73. PMID 15603791 DOI: 10.1016/J.Biomaterials.2004.08.008  0.21
2006 Guo Z, Bussard KM, Chatterjee K, Miller R, Vogler EA, Siedlecki CA. Mathematical modeling of material-induced blood plasma coagulation. Biomaterials. 27: 796-806. PMID 16099033 DOI: 10.1016/J.Biomaterials.2005.06.021  0.205
2001 Siedlecki CA, Bussard KM, Vogler EA. FXII INTERACTIONS WITH BIOMATERIAL SURFACES Asaio Journal. 47: 170. DOI: 10.1097/00002480-200103000-00275  0.192
2015 Booth CH, Mutkus L, Bussard K, Spaeth E, Andreeff M, Marini FC. Mesenchymal stem/stromal cell-targeted therapies for solid tumors and hematological malignancies Targeted Therapy of Acute Myeloid Leukemi. 799-819. DOI: 10.1007/978-1-4939-1393-0_43  0.173
2020 Agostini LC, Jain A, Shupp A, Nevler A, McCarthy G, Bussard KM, Yeo CJ, Brody JR. Combined targeting of PARG and Wee1 causes decreased cell survival and DNA damage in an S-phase dependent manner. Molecular Cancer Research : McR. PMID 33257507 DOI: 10.1158/1541-7786.MCR-20-0708  0.153
2002 Bussard KM, Vogler EA, Siedlecki CA. Effective production of FXIIa and thrombin by model biomaterials Proceedings of the Ieee Annual Northeast Bioengineering Conference, Nebec. 2002: 129-130. DOI: 10.1109/NEBC.2002.999499  0.068
2003 Bussard KM, Zapanta CM, Rosenberg G, Pae WE, Siedlecki CA. THROMBOELASTOGRAPH EVALUATION OF BOVINE BLOOD Asaio Journal. 49: 222. DOI: 10.1097/00002480-200303000-00323  0.016
2004 McAfee P, Cunningham BW, Holtsapple G, Bussard K, Guyer R, Blumenthal S, Dmitriev A, Maxwell J, Isaza J, Regan J. 93. A prospective randomized FDA study of the Charité disc replacement—a radiographic outcome analysis of 276 consecutive patients The Spine Journal. 4: S48. DOI: 10.1016/J.Spinee.2004.05.094  0.014
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