Michael I. Schimerlik - Publications

Affiliations: 
1984-1986 Biochemistry and Biophysics Oregon State University, Corvallis 

81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

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Year Citation  Score
2014 Bajaj G, Hau AM, Hsu P, Gafken PR, Schimerlik MI, Ishmael JE. Identification of an atypical calcium-dependent calmodulin binding site on the C-terminal domain of GluN2A. Biochemical and Biophysical Research Communications. 444: 588-94. PMID 24491550 DOI: 10.1016/j.bbrc.2014.01.111  0.68
2009 Harder ME, Malencik DA, Yan X, Broderick D, Leid M, Anderson SR, Deinzer ML, Schimerlik MI. Equilibrium unfolding of the retinoid X receptor ligand binding domain and characterization of an unfolding intermediate. Biophysical Chemistry. 141: 1-10. PMID 19167149 DOI: 10.1016/j.bpc.2008.12.001  0.68
2009 Bajaj G, Zhang Y, Schimerlik MI, Hau AM, Yang J, Filtz TM, Kioussi C, Ishmael JE. N-methyl-D-aspartate receptor subunits are non-myosin targets of myosin regulatory light chain. The Journal of Biological Chemistry. 284: 1252-66. PMID 18945678 DOI: 10.1074/jbc.M801861200  0.68
2008 Simonich MT, McQuistan T, Jubert C, Pereira C, Hendricks JD, Schimerlik M, Zhu B, Dashwood RH, Williams DE, Bailey GS. Low-dose dietary chlorophyll inhibits multi-organ carcinogenesis in the rainbow trout. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 46: 1014-24. PMID 18069110 DOI: 10.1016/j.fct.2007.10.034  0.68
2007 Liu D, Guo J, Luo Y, Broderick DJ, Schimerlik MI, Pezzuto JM, van Breemen RB. Screening for ligands of human retinoid X receptor-alpha using ultrafiltration mass spectrometry. Analytical Chemistry. 79: 9398-402. PMID 17997524 DOI: 10.1021/ac701701k  0.68
2007 Yan X, Pérez E, Leid M, Schimerlik MI, de Lera AR, Deinzer ML. Deuterium exchange and mass spectrometry reveal the interaction differences of two synthetic modulators of RXRalpha LBD. Protein Science : a Publication of the Protein Society. 16: 2491-501. PMID 17905826 DOI: 10.1110/ps.073019707  0.68
2006 Yan X, Deinzer ML, Schimerlik MI, Broderick D, Leid ME, Dawson MI. Investigation of ligand interactions with human RXRalpha by hydrogen/deuterium exchange and mass spectrometry. Journal of the American Society For Mass Spectrometry. 17: 1510-7. PMID 16872832 DOI: 10.1016/j.jasms.2006.05.016  0.68
2004 Harder ME, Deinzer ML, Leid ME, Schimerlik MI. Global analysis of three-state protein unfolding data. Protein Science : a Publication of the Protein Society. 13: 2207-22. PMID 15273314 DOI: 10.1110/ps.03229504  0.68
2004 Yan X, Broderick D, Leid ME, Schimerlik MI, Deinzer ML. Dynamics and ligand-induced solvent accessibility changes in human retinoid X receptor homodimer determined by hydrogen deuterium exchange and mass spectrometry. Biochemistry. 43: 909-17. PMID 14744134 DOI: 10.1021/bi030183c  0.68
2002 Zhang YH, Yan X, Maier CS, Schimerlik MI, Deinzer ML. Conformational analysis of intermediates involved in the in vitro folding pathways of recombinant human macrophage colony stimulating factor beta by sulfhydryl group trapping and hydrogen/deuterium pulsed labeling. Biochemistry. 41: 15495-504. PMID 12501178 DOI: 10.1021/bi0203841  0.68
2002 Yan X, Zhang H, Watson J, Schimerlik MI, Deinzer ML. Hydrogen/deuterium exchange and mass spectrometric analysis of a protein containing multiple disulfide bonds: Solution structure of recombinant macrophage colony stimulating factor-beta (rhM-CSFbeta). Protein Science : a Publication of the Protein Society. 11: 2113-24. PMID 12192067 DOI: 10.1110/ps.0204402  0.68
2002 Wolthers KR, Schimerlik MI. Effects of Ca(2+)-activated calmodulin on neuronal nitric oxide synthase reductase activity and binding of substrates: pH dependence of kinetic parameters. Biochemistry. 41: 205-14. PMID 11772018 DOI: 10.1021/bi010947t  0.68
2002 Wolthers KR, Schimerlik MI. Neuronal nitric oxide synthase: substrate and solvent kinetic isotope effects on the steady-state kinetic parameters for the reduction of 2,6-dichloroindophenol and cytochrome c(3+). Biochemistry. 41: 196-204. PMID 11772017 DOI: 10.1021/bi0109461  0.68
2002 Mosser VA, Amana IJ, Schimerlik MI. Kinetic analysis of M2 muscarinic receptor activation of Gi in Sf9 insect cell membranes. The Journal of Biological Chemistry. 277: 922-31. PMID 11689554 DOI: 10.1074/jbc.M104210200  0.68
2002 Stevens JF, Miranda CL, Wolthers KR, Schimerlik M, Deinzer ML, Buhler DR. Identification and in vitro biological activities of hop proanthocyanidins: Inhibition of nNOS activity and scavenging of reactive nitrogen species Journal of Agricultural and Food Chemistry. 50: 3435-3443. DOI: 10.1021/jf0116202  0.68
2002 Yan X, Zhang HY, Schimerlik MI, Deinzer ML. Analysis of the three-dimensional solution structure of a protein with multiple disulfide bonds by H/D ESI-MS Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 115-116.  0.68
2002 Zhang YH, Yan X, Maier C, Schimerlik MI, Deinzer ML. Oxidative folding of rhm-CSFβ by disulfide bond quenching: A folding funnel Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 271-272.  0.68
2001 Schimerlik MI. Overview of membrane protein solubilization. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 5.9. PMID 18428507 DOI: 10.1002/0471142301.ns0509s02  0.68
2001 Zhang YH, Yan X, Maier CS, Schimerlik MI, Deinzer ML. Structural comparison of recombinant human macrophage colony stimulating factor beta and a partially reduced derivative using hydrogen deuterium exchange and electrospray ionization mass spectrometry. Protein Science : a Publication of the Protein Society. 10: 2336-45. PMID 11604539 DOI: 10.1110/ps.16701  0.68
2001 Wolthers KR, Schimerlik MI. Reaction of neuronal nitric-oxide synthase with 2,6-dichloroindolphenol and cytochrome c3+: influence of the electron acceptor and binding of Ca2+-activated calmodulin on the kinetic mechanism. Biochemistry. 40: 4722-37. PMID 11294640 DOI: 10.1021/bi0023495  0.68
2000 Maier CS, Yan X, Harder ME, Schimerlik MI, Deinzer ML, Pasa-Tolić L, Smith RD. Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometric analysis of the recombinant human macrophage colony stimulating factor beta and derivatives. Journal of the American Society For Mass Spectrometry. 11: 237-43. PMID 10697819 DOI: 10.1016/S1044-0305(99)00139-7  0.68
1999 Reddy AP, Harttig U, Barth MC, Baird WM, Schimerlik M, Hendricks JD, Bailey GS. Inhibition of dibenzo[a,l]pyrene-induced multi-organ carcinogenesis by dietary chlorophyllin in rainbow trout. Carcinogenesis. 20: 1919-26. PMID 10506105 DOI: 10.1093/carcin/20.10.1919  0.68
1999 Hayashi T, Schimerlik M, Bailey G. Mechanisms of chlorophyllin anticarcinogenesis: Dose-responsive inhibition of aflatoxin uptake and biodistribution following oral co- administration in rainbow trout Toxicology and Applied Pharmacology. 158: 132-140. PMID 10406928 DOI: 10.1006/taap.1999.8695  0.68
1999 Schimerlik MI, Peterson VJ, Hobbs PD, Dawson MI, Leid M. Kinetic and thermodynamic analysis of 9-cis-retinoic acid binding to retinoid X receptor alpha. Biochemistry. 38: 6732-40. PMID 10346893 DOI: 10.1021/bi9829478  0.68
1999 Maier CS, Schimerlik MI, Deinzer ML. Thermal denaturation of Escherichia coli thioredoxin studied by hydrogen/deuterium exchange and electrospray ionization mass spectrometry: monitoring a two-state protein unfolding transition. Biochemistry. 38: 1136-43. PMID 9894011 DOI: 10.1021/bi981938w  0.68
1999 Vogel WK, Peterson GL, Broderick DJ, Mosser VA, Schimerlik MI. Double mutant cycle analysis of aspartate 69, 97, and 103 to asparagine mutants in the m2 muscarinic acetylcholine receptor. Archives of Biochemistry and Biophysics. 361: 283-94. PMID 9882458 DOI: 10.1006/abbi.1998.0985  0.68
1997 Vogel WK, Sheehan DM, Schimerlik MI. Site-directed mutagenesis on the m2 muscarinic acetylcholine receptor: the significance of Tyr403 in the binding of agonists and functional coupling. Molecular Pharmacology. 52: 1087-94. PMID 9415719  0.68
1996 Bulseco DA, Schimerlik MI. Single amino acid substitutions in the pm2 muscarinic receptor alter receptor/G protein coupling without changing physiological responses. Molecular Pharmacology. 49: 132-41. PMID 8569698  0.68
1995 Hirschberg BT, Mosser VA, Peterson GL, Toumadje A, Vogel WK, Johnson WC, Schimerlik MI. Kinetic and biophysical analysis of the m2 muscarinic receptor. Life Sciences. 56: 907-13. PMID 10188792 DOI: 10.1016/0024-3205(95)00027-4  0.68
1995 Vogel WK, Mosser VA, Bulseco DA, Schimerlik MI. Porcine m2 muscarinic acetylcholine receptor-effector coupling in Chinese hamster ovary cells. The Journal of Biological Chemistry. 270: 15485-93. PMID 7797541 DOI: 10.1074/jbc.270.26.15485  0.68
1995 Peterson GL, Toumadje A, Johnson WC, Schimerlik MI. Purification of recombinant porcine m2 muscarinic acetylcholine receptor from Chinese hamster ovary cells. Circular dichroism spectra and ligand binding properties. The Journal of Biological Chemistry. 270: 17808-14. PMID 7629081 DOI: 10.1074/jbc.270.30.17808  0.68
1995 Breinholt V, Schimerlik M, Dashwood R, Bailey G. Mechanisms of chlorophyllin anticarcinogenesis against aflatoxin B1: Complex formation with the carcinogen Chemical Research in Toxicology. 8: 506-514. PMID 7548730  0.68
1994 Hirschberg BT, Schimerlik MI. A kinetic model for oxotremorine M binding to recombinant porcine m2 muscarinic receptors expressed in Chinese hamster ovary cells. The Journal of Biological Chemistry. 269: 26127-35. PMID 7929325  0.68
1993 Bennett SE, Schimerlik MI, Mosbaugh DW. Kinetics of the uracil-DNA glycosylase/inhibitor protein association. Ung interaction with Ugi, nucleic acids, and uracil compounds. The Journal of Biological Chemistry. 268: 26879-85. PMID 8262921  0.68
1990 Tota MR, Schimerlik MI. Partial agonist effects on the interaction between the atrial muscarinic receptor and the inhibitory guanine nucleotide-binding protein in a reconstituted system. Molecular Pharmacology. 37: 996-1004. PMID 2163022  0.68
1990 Schimerlik MI. Structure and function of muscarinic receptors. Progress in Brain Research. 84: 11-9. PMID 2125130 DOI: 10.1016/S0079-6123(08)60884-5  0.68
1990 Tota MR, Xia ZQ, Storm DR, Schimerlik MI. Reconstitution of muscarinic receptor-mediated inhibition of adenylyl cyclase. Molecular Pharmacology. 37: 950-7. PMID 2113606  0.68
1990 Tatsumi H, Costa M, Schimerlik M, North RA. Potassium conductance increased by noradrenaline, opioids, somatostatin, and G-proteins: whole-cell recording from guinea pig submucous neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 1675-82. PMID 1970605  0.68
1989 Schimerlik MI. Structure and regulation of muscarinic receptors. Annual Review of Physiology. 51: 217-27. PMID 2496642 DOI: 10.1146/annurev.ph.51.030189.001245  0.68
1989 Leid M, Schimerlik MI, Murray TF. Agonist radioligand interactions with the solubilized porcine atrial A1 adenosine receptor. Molecular Pharmacology. 35: 450-7. PMID 2495433  0.68
1988 Peterson GL, Rosenbaum LC, Schimerlik MI. Solubilization and hydrodynamic properties of pig atrial muscarinic acetylcholine receptor in dodecyl beta-D-maltoside. The Biochemical Journal. 255: 553-60. PMID 3202834  0.68
1988 Leid M, Schimerlik MI, Murray TF. Characterization of agonist radioligand interactions with porcine atrial A1 adenosine receptors. Molecular Pharmacology. 34: 334-9. PMID 3047553  0.68
1987 Hennessey JP, Manavalan P, Johnson WC, Malencik DA, Anderson SR, Schimerlik MI, Shalitin Y. Conformational transitions of calmodulin as studied by vacuum-uv CD. Biopolymers. 26: 561-71. PMID 3567327 DOI: 10.1002/bip.360260409  0.68
1987 Rosenbaum LC, Malencik DA, Anderson SR, Tota MR, Schimerlik MI. Phosphorylation of the porcine atrial muscarinic acetylcholine receptor by cyclic AMP dependent protein kinase. Biochemistry. 26: 8183-8. PMID 3442651  0.68
1987 Luetje CW, Brumwell C, Norman MG, Peterson GL, Schimerlik MI, Nathanson NM. Isolation and characterization of monoclonal antibodies specific for the cardiac muscarinic acetylcholine receptor. Biochemistry. 26: 6892-6. PMID 3427051  0.68
1987 Tota MR, Kahler KR, Schimerlik MI. Reconstitution of the purified porcine atrial muscarinic acetylcholine receptor with purified porcine atrial inhibitory guanine nucleotide binding protein. Biochemistry. 26: 8175-82. PMID 3126798  0.68
1987 Peralta EG, Winslow JW, Peterson GL, Smith DH, Ashkenazi A, Ramachandran J, Schimerlik MI, Capon DJ. Primary structure and biochemical properties of an M2 muscarinic receptor. Science (New York, N.Y.). 236: 600-5. PMID 3107123 DOI: 10.1126/science.3107123  0.68
1987 Ashkenazi A, Winslow JW, Peralta EG, Peterson GL, Schimerlik MI, Capon DJ, Ramachandran J. An M2 muscarinic receptor subtype coupled to both adenylyl cyclase and phosphoinositide turnover. Science (New York, N.Y.). 238: 672-5. PMID 2823384  0.68
1986 Peterson GL, Rosenbaum LC, Broderick DJ, Schimerlik MI. Physical properties of the purified cardiac muscarinic acetylcholine receptor. Biochemistry. 25: 3189-202. PMID 3730355  0.68
1986 Manavalan P, Mittelstaedt DM, Schimerlik MI, Johnson WC. Conformational analysis of thymidylate synthase from amino acid sequence and circular dichroism. Biochemistry. 25: 6650-5. PMID 3098289  0.68
1986 Mittelstaedt DM, Schimerlik MI. Stopped-flow studies of 2'-deoxynucleotide binding to thymidylate synthase. Archives of Biochemistry and Biophysics. 245: 417-25. PMID 3082285 DOI: 10.1016/0003-9861(86)90233-X  0.68
1985 Mittelstaedt D, Schimerlik M. Stopped-flow studies on thymidylate synthase Federation Proceedings. 44: No. 8186.  0.68
1984 Peterson GL, Schimerlik MI. Large scale preparation and characterization of membrane-bound and detergent-solubilized muscarinic acetylcholine receptor from pig atria. Preparative Biochemistry. 14: 33-74. PMID 6718325 DOI: 10.1080/10826068408070612  0.68
1984 Peterson GL, Herron GS, Yamaki M, Fullerton DS, Schimerlik MI. Purification of the muscarinic acetylcholine receptor from porcine atria. Proceedings of the National Academy of Sciences of the United States of America. 81: 4993-7. PMID 6589642  0.68
1984 Cremo C, Schimerlik MI. Photoaffinity labeling of the solubilized, partially purified muscarinic acetylcholine receptor from porcine atria by p-azidoatropine methyl iodide. Biochemistry. 23: 3494-501. PMID 6547852  0.68
1984 Herron GS, Schimerlik MI. Protein composition of the atrial muscarinic acetylcholine receptor partially purified by wheat germ agglutinin affinity chromatography. Archives of Biochemistry and Biophysics. 230: 533-42. PMID 6546850 DOI: 10.1016/0003-9861(84)90434-X  0.68
1983 Cremo C, Schimerlik MI. Histrionicotoxin and alkylguanidine interactions with the solubilized and membrane-bound muscarinic acetylcholine receptor from porcine atria. Archives of Biochemistry and Biophysics. 224: 506-14. PMID 6870276 DOI: 10.1016/0003-9861(83)90238-2  0.68
1983 Herron GS, Schimerlik MI. Glycoprotein properties of the solubilized atrial muscarinic acetylcholine receptor. Journal of Neurochemistry. 41: 1414-20. PMID 6688633  0.68
1983 Deffo T, Fullerton DS, Kihara M, McParland RH, Becker RR, Simat BM, From AH, Ahmed K, Schimerlik MI. Photoaffinity labeling of the sodium- and potassium-activated adenosinetriphosphatase with a cardiac glycoside containing the photoactive group on the C-17 side chain. Biochemistry. 22: 6303-9. PMID 6318813  0.68
1982 Schimerlik MI, Malencik DA, Anderson SR, Shalitin Y. Rapid kinetic studies of calmodulin interactions with calcium and troponin I as monitored by anthroylcholine fluorescence. Biochemical and Biophysical Research Communications. 106: 1331-9. PMID 7115403 DOI: 10.1016/0006-291X(82)91259-1  0.68
1982 Peterson GL, Schimerlik MI. Preparation and characterization of muscarinic-acetylcholine-receptor-enriched membranes from pig atria. The Biochemical Journal. 202: 475-81. PMID 7092826  0.68
1982 Herron GS, Miller S, Manley WL, Schimerlik MI. Ligand interactions with the solubilized porcine atrial muscarinic receptor. Biochemistry. 21: 515-20. PMID 7066304  0.68
1982 Cremo C, Schimerlik M. Histrionicotoxin and alkyl guanidine interactions with the solubilized and membrane-bound muscarinic acetylcholine receptor from porcine atria: Effects of varying chain length on ligand affinity Federation Proceedings. 41: No. 5494.  0.68
1981 Malencik DA, Anderson SR, Shalitin Y, Schimerlik MI. Rapid kinetic studies on calcium interactions with native and fluorescently labeled calmodulin. Biochemical and Biophysical Research Communications. 101: 390-5. PMID 7306084 DOI: 10.1016/0006-291X(81)91272-9  0.68
1981 Cremo CR, Herron GS, Schimerlik MI. Solubilization of the atrial muscarinic acetylcholine receptor: a new detergent system and rapid assays. Analytical Biochemistry. 115: 331-8. PMID 7304963 DOI: 10.1016/0003-2697(81)90014-2  0.68
1980 Schimerlik MI, Searles RP. Ligand interactions with membrane-bound porcine atrial muscarinic receptor(s). Biochemistry. 19: 3407-13. PMID 7407049  0.68
1979 Schimerlik MI, Quast U, Raftery MA. Ligand-induced changes in membrane-bound acetylcholine receptor observed by ethidium fluorescence. 3. Stopped-flow studies with histrionicotoxin. Biochemistry. 18: 1902-6. PMID 435454  0.68
1979 Quast U, Schimerlik MI, Raftery MA. Ligand-induced changes in membrane-bound acetylcholine receptor observed by ethidium fluorescence. 2. Stopped-flow studies with agonists and antagonists. Biochemistry. 18: 1891-901. PMID 435453  0.68
1979 Schimerlik M, Quast U, Raftery MA. Ligand-induced changes in membrane-bound acetylcholine receptor observed by ethidium fluorescence. 1. Equilibrium studies Biochemistry. 18: 1884-1890. PMID 435452  0.68
1979 Blanchard SG, Quast U, Reed K, Lee T, Schimerlik MI, Vandlen R, Claudio T, Strader CD, Moore HP, Raftery MA. Interaction of [125I]-alpha-bungarotoxin with acetylcholine receptor from Torpedo californica. Biochemistry. 18: 1875-83. PMID 435451  0.68
1979 Bode J, Moody T, Schimerlik M, Raftery M. Uses of fluorescent cholinergic analogues to study binding sites for cholinergic ligands in Torpedo californica acetylcholine receptor Biochemistry. 18: 1855-1861. PMID 435448  0.68
1979 Raftery M, Blanchard S, Elliott J, Hartig P, Moore HP, Quast U, Schimerlik M, Witzemann V, Wu W. Properties of Torpedo californica acetylcholine receptor. Advances in Cytopharmacology. 3: 159-82. PMID 382781  0.68
1978 Quast U, Schimerlik M, Lee T, Witzemann V, Blanchard S, Raftery MA. Ligand-induced conformation changes in Torpedo californica membrane-bound acetylcholine receptor Biochemistry. 17: 2405-2414. PMID 678518  0.68
1978 Quast U, Schimerlik M, Raftery MA. Stopped flow kinetics of carbamylcholine binding to membrane bound acetylcholine receptor Biochemical and Biophysical Research Communications. 81: 955-964. PMID 666804 DOI: 10.1016/0006-291X(78)91444-4  0.68
1977 Schimerlik MI, Cleland WW. Inhibition and alternate-substrate studies on the mechanism of malic enzyme. Biochemistry. 16: 565-70. PMID 836801 DOI: 10.1021/bi00623a001  0.68
1977 Lee T, Witzemann V, Schimerlik M, Raftery MA. Cholinergic ligand-induced affinity changes in Torpedo californica acetylcholine receptor. Archives of Biochemistry and Biophysics. 183: 57-63. PMID 562135 DOI: 10.1016/0003-9861(77)90418-0  0.68
1977 Schimerlik MI, Cleland WW. pH variation of the kinetic parameters and the catalytic mechanism of malic enzyme. Biochemistry. 16: 576-83. PMID 13821  0.68
1977 Schimerlik MI, Grimshaw CE, Cleland WW. Determination of the rate-limiting steps for malic enzyme by the use of isotope effects and other kinetic studies. Biochemistry. 16: 571-6. PMID 13820 DOI: 10.1021/bi00623a002  0.68
1976 Schimerlik M, Raftery MA. A fluorescence probe of acetylcholine receptor conformation and local anesthetic binding Biochemical and Biophysical Research Communications. 73: 607-613. PMID 1008877 DOI: 10.1016/0006-291X(76)90853-6  0.68
1975 Schimerlik MI, Rife JE, Cleland WW. Equilibrium perturbation by isotope substitution. Biochemistry. 14: 5347-54. PMID 1191642 DOI: 10.1021/bi00695a020  0.68
1973 Schimerlik MI, Cleland WW. Inhibition of creatine kinase by chromium nucleotides. The Journal of Biological Chemistry. 248: 8418-23. PMID 4797017  0.68
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