Pascal Mercier, Ph.D. - Publications

Affiliations: 
2003 University of Alberta, Edmonton, Alberta, Canada 
Area:
structure, dynamics and function of proteins

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Markin CJ, Mercier P, Spyracopoulos L. Role of Polyubiquitin Chain Flexibility in the Catalytic Mechanism of Cullin-RING Ubiquitin Ligases. The Journal of Physical Chemistry. B. PMID 30590923 DOI: 10.1021/acs.jpcb.8b10706  0.8
2015 Kumar A, Aguirre JD, Condos TE, Martinez-Torres RJ, Chaugule VK, Toth R, Sundaramoorthy R, Mercier P, Knebel A, Spratt DE, Barber KR, Shaw GS, Walden H. Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis. The Embo Journal. 34: 2506-21. PMID 26254304 DOI: 10.15252/embj.201592337  0.8
2014 Sarkar S, Döring A, Zemp FJ, Silva C, Lun X, Wang X, Kelly J, Hader W, Hamilton M, Mercier P, Dunn JF, Kinniburgh D, van Rooijen N, Robbins S, Forsyth P, et al. Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells. Nature Neuroscience. 17: 46-55. PMID 24316889 DOI: 10.1038/nn.3597  0.4
2014 Chevillard-Briet M, Quaranta M, Grézy A, Mattera L, Courilleau C, Philippe M, Mercier P, Corpet D, Lough J, Ueda T, Fukunaga R, Trouche D, Escaffit F. Interplay between chromatin-modifying enzymes controls colon cancer progression through Wnt signaling. Human Molecular Genetics. 23: 2120-31. PMID 24287617 DOI: 10.1093/hmg/ddt604  0.8
2014 Jia W, Wang X, Imani S, Bandodkar AJ, Ramírez J, Mercier PP, Wang J. Wearable textile biofuel cells for powering electronics Journal of Materials Chemistry A. 2: 18184-18189. DOI: 10.1039/c4ta04796f  0.4
2014 Glaves JP, Li MX, Mercier P, Fahlman RP, Sykes BD. High-throughput, multi-platform metabolomics on very small volumes: 1H NMR metabolite identification in an unadulterated tube-in-tube system Metabolomics. DOI: 10.1007/s11306-014-0678-2  0.8
2013 Sarkar S, Döring A, Zemp FJ, Silva C, Lun X, Wang X, Kelly J, Hader W, Hamilton M, Mercier P, Dunn JF, Kinniburgh D, van Rooijen N, Robbins S, Forsyth P, et al. Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells. Annals of Neurosciences. 20: 154. PMID 25206040 DOI: 10.5214/ans.0972.7531.200407  0.4
2013 Bai JJ, Safadi SS, Mercier P, Barber KR, Shaw GS. Ataxin-3 is a multivalent ligand for the parkin Ubl domain. Biochemistry. 52: 7369-76. PMID 24063750 DOI: 10.1021/bi400780v  0.8
2013 Spratt DE, Mercier P, Shaw GS. Structure of the HHARI catalytic domain shows glimpses of a HECT E3 ligase. Plos One. 8: e74047. PMID 24058416 DOI: 10.1371/journal.pone.0074047  0.8
2013 Spratt DE, Martinez-Torres RJ, Noh YJ, Mercier P, Manczyk N, Barber KR, Aguirre JD, Burchell L, Purkiss A, Walden H, Shaw GS. A molecular explanation for the recessive nature of parkin-linked Parkinson's disease. Nature Communications. 4: 1983. PMID 23770917 DOI: 10.1038/ncomms2983  0.8
2012 Pichery M, Mirey E, Mercier P, Lefrancais E, Dujardin A, Ortega N, Girard JP. Endogenous IL-33 is highly expressed in mouse epithelial barrier tissues, lymphoid organs, brain, embryos, and inflamed tissues: in situ analysis using a novel Il-33-LacZ gene trap reporter strain. Journal of Immunology (Baltimore, Md. : 1950). 188: 3488-95. PMID 22371395 DOI: 10.4049/jimmunol.1101977  0.8
2011 Mercier P, Lewis MJ, Chang D, Baker D, Wishart DS. Towards automatic metabolomic profiling of high-resolution one-dimensional proton NMR spectra. Journal of Biomolecular Nmr. 49: 307-23. PMID 21360156 DOI: 10.1007/s10858-011-9480-x  0.8
2011 Julien O, Mercier P, Allen CN, Fisette O, Ramos CH, Lagüe P, Blumenschein TM, Sykes BD. Is there nascent structure in the intrinsically disordered region of troponin I? Proteins. 79: 1240-50. PMID 21322033 DOI: 10.1002/prot.22959  0.8
2009 Julien O, Mercier P, Crane ML, Sykes BD. The effect of the cosolvent trifluoroethanol on a tryptophan side chain orientation in the hydrophobic core of troponin C. Protein Science : a Publication of the Protein Society. 18: 1165-74. PMID 19472326 DOI: 10.1002/pro.121  0.8
2009 Teng R, Junankar PR, Bubb WA, Rae C, Mercier P, Kirk K. Metabolite profiling of the intraerythrocytic malaria parasite Plasmodium falciparum by (1)H NMR spectroscopy. Nmr in Biomedicine. 22: 292-302. PMID 19021153 DOI: 10.1002/nbm.1323  0.8
2008 Baryshnikova OK, Robertson IM, Mercier P, Sykes BD. The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I. Biochemistry. 47: 10950-60. PMID 18803402 DOI: 10.1021/bi801165c  0.8
2008 Julien O, Mercier P, Spyracopoulos L, Corrie JE, Sykes BD. NMR studies of the dynamics of a bifunctional rhodamine probe attached to troponin C. Journal of the American Chemical Society. 130: 2602-9. PMID 18251471 DOI: 10.1021/ja0772694  0.8
2007 Mercier P, Lewis MJ, Hau DD, Saltibus LF, Xiao W, Spyracopoulos L. Structure, interactions, and dynamics of the RING domain from human TRAF6. Protein Science : a Publication of the Protein Society. 16: 602-14. PMID 17327397 DOI: 10.1110/ps.062358007  0.8
2006 Weljie AM, Newton J, Mercier P, Carlson E, Slupsky CM. Targeted profiling: quantitative analysis of 1H NMR metabolomics data. Analytical Chemistry. 78: 4430-42. PMID 16808451 DOI: 10.1021/ac060209g  0.8
2005 Wang X, Mercier P, Letourneau PJ, Sykes BD. Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies. Protein Science : a Publication of the Protein Society. 14: 2447-60. PMID 16131667 DOI: 10.1110/ps.051595805  0.8
2004 Lindhout DA, Litowski JR, Mercier P, Hodges RS, Sykes BD. NMR solution structure of a highly stable de novo heterodimeric coiled-coil. Biopolymers. 75: 367-75. PMID 15457434 DOI: 10.1002/bip.20150  0.8
2004 Bergoglio V, Fréchet M, Philippe M, Bieth A, Mercier P, Morello D, Lacroix-Tricki M, Delsol G, Hoffmann JS, Cazaux C. Evidence of finely tuned expression of DNA polymerase β in vivo using transgenic mice Febs Letters. 566: 147-150. PMID 15147885 DOI: 10.1016/j.febslet.2004.04.020  0.8
2004 Kawulka KE, Sprules T, Diaper CM, Whittal RM, McKay RT, Mercier P, Zuber P, Vederas JC. Structure of subtilosin A, a cyclic antimicrobial peptide from Bacillus subtilis with unusual sulfur to alpha-carbon cross-links: formation and reduction of alpha-thio-alpha-amino acid derivatives. Biochemistry. 43: 3385-95. PMID 15035610 DOI: 10.1021/bi0359527  0.8
2003 Ferguson RE, Sun YB, Mercier P, Brack AS, Sykes BD, Corrie JE, Trentham DR, Irving M. In situ orientations of protein domains: troponin C in skeletal muscle fibers. Molecular Cell. 11: 865-74. PMID 12718873 DOI: 10.1016/S1097-2765(03)00096-0  0.8
2003 Kawulka K, Sprules T, McKay RT, Mercier P, Diaper CM, Zuber P, Vederas JC. Structure of subtilosin A, an antimicrobial peptide from Bacillus subtilis with unusual posttranslational modifications linking cysteine sulfurs to alpha-carbons of phenylalanine and threonine. Journal of the American Chemical Society. 125: 4726-7. PMID 12696888 DOI: 10.1021/ja029654t  0.8
2003 Mercier P, Ferguson RE, Irving M, Corrie JE, Trentham DR, Sykes BD. NMR structure of a bifunctional rhodamine labeled N-domain of troponin C complexed with the regulatory "switch" peptide from troponin I: implications for in situ fluorescence studies in muscle fibers. Biochemistry. 42: 4333-48. PMID 12693929 DOI: 10.1021/bi027041n  0.8
2003 Levadoux-Martin M, Gouble A, Jégou B, Vallet-Erdtmann V, Auriol J, Mercier P, Morello D. Impaired gametonesis in mice that overexpress the RNA-binding protein HuR Embo Reports. 4: 394-399. PMID 12671683 DOI: 10.1038/sj.embor.embor803  0.8
2002 Gouble A, Grazide S, Meggetto F, Mercier P, Delsol G, Morello D. A new player in oncogenesis: AUF1/hnRNPD overexpression leads to tumorigenesis in transgenic mice Cancer Research. 62: 1489-1495. PMID 11888925  0.8
2001 Chatelin S, Wehrlé R, Mercier P, Morello D, Sotelo C, Weber MJ. Neuronal promoter of human aromatic L-amino acid decarboxylase gene directs transgene expression to the adult floor plate and aminergic nuclei induced by the isthmus. Brain Research. Molecular Brain Research. 97: 149-60. PMID 11750071 DOI: 10.1016/S0169-328X(01)00318-7  0.8
2001 Houzet L, Morello D, Defrance P, Mercier P, Huez G, Kruys V. Regulated control by granulocyte-macrophage colony-stimulating factor AU-rich element during mouse embryogenesis Blood. 98: 1281-1288. PMID 11520772 DOI: 10.1182/blood.V98.5.1281  0.8
2001 Mercier P, Spyracopoulos L, Sykes BD. Structure, dynamics, and thermodynamics of the structural domain of troponin C in complex with the regulatory peptide 1-40 of troponin I. Biochemistry. 40: 10063-77. PMID 11513585 DOI: 10.1021/bi010748+  0.8
2001 Créancier L, Mercier P, Prats AC, Morello D. c-myc internal ribosome entry site activity is developmentally controlled and subjected to a strong translational repression in adult transgenic mice Molecular and Cellular Biology. 21: 1833-1840. PMID 11238920 DOI: 10.1128/MCB.21.5.1833-1840.2001  0.8
2000 Créancier L, Morello D, Mercier P, Prats AC. Fibroblast growth factor 2 internal ribosome entry site (IRES) activity ex vivo and in transgenic mice reveals a stringent tissue-specific regulation Journal of Cell Biology. 150: 275-281. PMID 10893274 DOI: 10.1083/jcb.150.1.275  0.8
2000 Mercier P, Li MX, Sykes BD. Role of the structural domain of troponin C in muscle regulation: NMR studies of Ca2+ binding and subsequent interactions with regions 1-40 and 96-115 of troponin I. Biochemistry. 39: 2902-11. PMID 10715110 DOI: 10.1021/bi992579n  0.8
2000 Cohen-Tannoudji M, Vandormael-Pournin S, Drezen JM, Mercier P, Babinet C, Morello D. lacZ sequences prevent regulated expression of housekeeping genes Mechanisms of Development. 90: 29-39. PMID 10585560 DOI: 10.1016/S0925-4773(99)00226-9  0.8
1999 Mercier P, Carrier V, Roy S, Savoie R. Raman spectroscopic measurements in self-pressurized aqueous solutions above 100°C: The melting of poly(G) and poly(G)·poly(C) Biopolymers. 49: 21-28. DOI: 10.1002/(SICI)1097-0282(199901)49:1<21::AID-BIP3>3.0.CO;2-Y  0.8
1997 Mercier P, Savoie R. Interaction of DNA with silica particles: A vibrational spectroscopic study Biospectroscopy. 3: 299-306.  0.8
1995 Mercier P, Simeone A, Cotelli F, Boncinelli E. Expression pattern of two otx genes suggests a role in specifying anterior body structures in zebrafish International Journal of Developmental Biology. 39: 559-573. PMID 8619954  0.8
1995 Nataf V, Mercier P, De Néchaud B, Guillemot JC, Capdevielle J, Lapointe F, Le Douarin NM. Melanoblast/melanocyte early marker (MelEM) is a glutathione S-transferase subunit. Experimental Cell Research. 218: 394-400. PMID 7737377 DOI: 10.1006/excr.1995.1171  0.8
1994 Lecoin L, Mercier P, Le Douarin NM. Growth of neural crest cells in vitro is enhanced by extracts from Silky Fowl embryonic tissues. Pigment Cell Research / Sponsored by the European Society For Pigment Cell Research and the International Pigment Cell Society. 7: 210-6. PMID 7855065  0.8
1993 Nataf V, Mercier P, Ziller C, Le Douarin NM. Novel markers of melanocyte differentiation in the avian embryo. Experimental Cell Research. 207: 171-82. PMID 7686497 DOI: 10.1006/excr.1993.1177  0.8
1984 LeBlanc J, Mercier P, Samson P. Diet-induced thermogenesis with relation to training state in female subjects Canadian Journal of Physiology and Pharmacology. 62: 334-337. PMID 6722659  0.8
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