Rodney K. Tweten - Publications

Affiliations: 
2010 University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States 
Website:
https://www.oumedicine.com/mi/faculty/rodney-k-tweten-phd

98 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Lawrence SL, Gorman MA, Feil SC, Mulhern TD, Kuiper MJ, Ratner AJ, Tweten RK, Morton CJ, Parker MW. Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins. Structure (London, England : 1993). PMID 27499440 DOI: 10.1016/j.str.2016.06.017  1
2015 Ellisdon AM, Reboul CF, Panjikar S, Huynh K, Oellig CA, Winter KL, Dunstone MA, Hodgson WC, Seymour J, Dearden PK, Tweten RK, Whisstock JC, McGowan S. Stonefish toxin defines an ancient branch of the perforin-like superfamily. Proceedings of the National Academy of Sciences of the United States of America. PMID 26627714 DOI: 10.1073/pnas.1507622112  1
2015 Tweten RK, Hotze EM, Wade KR. The Unique Molecular Choreography of Giant Pore Formation by the Cholesterol-Dependent Cytolysins of Gram-Positive Bacteria. Annual Review of Microbiology. 69: 323-40. PMID 26488276 DOI: 10.1146/annurev-micro-091014-104233  1
2015 Lawrence SL, Feil SC, Morton CJ, Farrand AJ, Mulhern TD, Gorman MA, Wade KR, Tweten RK, Parker MW. Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation. Scientific Reports. 5: 14352. PMID 26403197 DOI: 10.1038/srep14352  1
2015 Farrand AJ, Hotze EM, Sato TK, Wade KR, Wimley WC, Johnson AE, Tweten RK. The Cholesterol-dependent Cytolysin Membrane-binding Interface Discriminates Lipid Environments of Cholesterol to Support β-Barrel Pore Insertion. The Journal of Biological Chemistry. 290: 17733-44. PMID 26032415 DOI: 10.1074/jbc.M115.656769  1
2015 Wade KR, Tweten RK. The Apicomplexan CDC/MACPF-like pore-forming proteins. Current Opinion in Microbiology. 26: 48-52. PMID 26025132 DOI: 10.1016/j.mib.2015.05.001  1
2015 Wade KR, Hotze EM, Kuiper MJ, Morton CJ, Parker MW, Tweten RK. An intermolecular electrostatic interaction controls the prepore-to-pore transition in a cholesterol-dependent cytolysin. Proceedings of the National Academy of Sciences of the United States of America. 112: 2204-9. PMID 25646411 DOI: 10.1073/pnas.1423754112  1
2015 Bolz DD, Li Z, McIndoo ER, Tweten RK, Bryant AE, Stevens DL. Cardiac myocyte dysfunction induced by streptolysin O is membrane pore and calcium dependent. Shock (Augusta, Ga.). 43: 178-84. PMID 25243426 DOI: 10.1097/SHK.0000000000000266  1
2015 Lukoyanova N, Kondos SC, Farabella I, Law RHP, Reboul CF, Caradoc-Davies TT, Spicer BA, Kleifeld O, Traore DAK, Ekkel SM, Voskoboinik I, Trapani JA, Hatfaludi T, Oliver K, Hotze EM, ... Tweten RK, et al. Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin Plos Biology. 13. DOI: 10.1371/journal.pbio.1002049  1
2014 Wade KR, Hotze EM, Briles DE, Tweten RK. Mouse, but not human, ApoB-100 lipoprotein cholesterol is a potent innate inhibitor of Streptococcus pneumoniae pneumolysin. Plos Pathogens. 10: e1004353. PMID 25188225 DOI: 10.1371/journal.ppat.1004353  1
2014 Harvey RM, Hughes CE, Paton AW, Trappetti C, Tweten RK, Paton JC. The impact of pneumolysin on the macrophage response to Streptococcus pneumoniae is strain-dependent. Plos One. 9: e103625. PMID 25105894 DOI: 10.1371/journal.pone.0103625  1
2014 Feil SC, Ascher DB, Kuiper MJ, Tweten RK, Parker MW. Structural studies of Streptococcus pyogenes streptolysin O provide insights into the early steps of membrane penetration. Journal of Molecular Biology. 426: 785-92. PMID 24316049 DOI: 10.1016/j.jmb.2013.11.020  1
2013 Sato TK, Tweten RK, Johnson AE. Disulfide-bond scanning reveals assembly state and β-strand tilt angle of the PFO β-barrel. Nature Chemical Biology. 9: 383-9. PMID 23563525 DOI: 10.1038/nchembio.1228  0.52
2013 Hotze EM, Le HM, Sieber JR, Bruxvoort C, McInerney MJ, Tweten RK. Identification and characterization of the first cholesterol-dependent cytolysins from Gram-negative bacteria. Infection and Immunity. 81: 216-25. PMID 23115036 DOI: 10.1128/IAI.00927-12  1
2012 Lawrence SL, Feil SC, Holien JK, Kuiper MJ, Doughty L, Dolezal O, Mulhern TD, Tweten RK, Parker MW. Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin. Frontiers in Immunology. 3: 330. PMID 23181061 DOI: 10.3389/fimmu.2012.00330  1
2012 Dowd KJ, Farrand AJ, Tweten RK. The cholesterol-dependent cytolysin signature motif: a critical element in the allosteric pathway that couples membrane binding to pore assembly. Plos Pathogens. 8: e1002787. PMID 22792065 DOI: 10.1371/journal.ppat.1002787  1
2012 Dunstone MA, Tweten RK. Packing a punch: the mechanism of pore formation by cholesterol dependent cytolysins and membrane attack complex/perforin-like proteins. Current Opinion in Structural Biology. 22: 342-9. PMID 22658510 DOI: 10.1016/j.sbi.2012.04.008  1
2012 Hotze EM, Wilson-Kubalek E, Farrand AJ, Bentsen L, Parker MW, Johnson AE, Tweten RK. Monomer-monomer interactions propagate structural transitions necessary for pore formation by the cholesterol-dependent cytolysins. The Journal of Biological Chemistry. 287: 24534-43. PMID 22645132 DOI: 10.1074/jbc.M112.380139  1
2012 Feil SC, Lawrence S, Mulhern TD, Holien JK, Hotze EM, Farrand S, Tweten RK, Parker MW. Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity. Structure (London, England : 1993). 20: 248-58. PMID 22325774 DOI: 10.1016/j.str.2011.11.017  1
2012 Hotze EM, Tweten RK. Membrane assembly of the cholesterol-dependent cytolysin pore complex. Biochimica Et Biophysica Acta. 1818: 1028-38. PMID 21835159 DOI: 10.1016/j.bbamem.2011.07.036  1
2011 Vadia S, Arnett E, Haghighat AC, Wilson-Kubalek EM, Tweten RK, Seveau S. The pore-forming toxin listeriolysin O mediates a novel entry pathway of L. monocytogenes into human hepatocytes. Plos Pathogens. 7: e1002356. PMID 22072970 DOI: 10.1371/journal.ppat.1002356  1
2011 Lencer WI, Tweten RK. To translocate or not: that is the problem. Cell Host & Microbe. 10: 179-80. PMID 21925105 DOI: 10.1016/j.chom.2011.08.009  1
2011 Wickham SE, Hotze EM, Farrand AJ, Polekhina G, Nero TL, Tomlinson S, Parker MW, Tweten RK. Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8alpha and C9. The Journal of Biological Chemistry. 286: 20952-62. PMID 21507937 DOI: 10.1074/jbc.M111.237446  1
2010 Farrand AJ, LaChapelle S, Hotze EM, Johnson AE, Tweten RK. Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface. Proceedings of the National Academy of Sciences of the United States of America. 107: 4341-6. PMID 20145114 DOI: 10.1073/pnas.0911581107  1
2009 LaChapelle S, Tweten RK, Hotze EM. Intermedilysin-receptor interactions during assembly of the pore complex: assembly intermediates increase host cell susceptibility to complement-mediated lysis. The Journal of Biological Chemistry. 284: 12719-26. PMID 19293153 DOI: 10.1074/jbc.M900772200  1
2009 Flanagan JJ, Tweten RK, Johnson AE, Heuck AP. Cholesterol exposure at the membrane surface is necessary and sufficient to trigger perfringolysin O binding. Biochemistry. 48: 3977-87. PMID 19292457 DOI: 10.1021/bi9002309  1
2009 Kennedy CL, Lyras D, Cordner LM, Melton-Witt J, Emmins JJ, Tweten RK, Rood JI. Pore-forming activity of alpha-toxin is essential for clostridium septicum-mediated myonecrosis. Infection and Immunity. 77: 943-51. PMID 19139192 DOI: 10.1128/IAI.01267-08  1
2008 Farrand S, Hotze E, Friese P, Hollingshead SK, Smith DF, Cummings RD, Dale GL, Tweten RK. Characterization of a streptococcal cholesterol-dependent cytolysin with a lewis y and b specific lectin domain. Biochemistry. 47: 7097-107. PMID 18553932 DOI: 10.1021/bi8005835  1
2008 Miersch S, Espey MG, Chaube R, Akarca A, Tweten R, Ananvoranich S, Mutus B. Plasma membrane cholesterol content affects nitric oxide diffusion dynamics and signaling. The Journal of Biological Chemistry. 283: 18513-21. PMID 18445594 DOI: 10.1074/jbc.M800440200  1
2008 Hu W, Ferris SP, Tweten RK, Wu G, Radaeva S, Gao B, Bronson RT, Halperin JA, Qin X. Rapid conditional targeted ablation of cells expressing human CD59 in transgenic mice by intermedilysin. Nature Medicine. 14: 98-103. PMID 18157141 DOI: 10.1038/nm1674  1
2007 Soltani CE, Hotze EM, Johnson AE, Tweten RK. Structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions. Proceedings of the National Academy of Sciences of the United States of America. 104: 20226-31. PMID 18077338 DOI: 10.1073/pnas.0708104105  1
2007 Soltani CE, Hotze EM, Johnson AE, Tweten RK. Specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin. The Journal of Biological Chemistry. 282: 15709-16. PMID 17412689 DOI: 10.1074/jbc.M701173200  1
2007 Rossjohn J, Polekhina G, Feil SC, Morton CJ, Tweten RK, Parker MW. Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins. Journal of Molecular Biology. 367: 1227-36. PMID 17328912 DOI: 10.1016/j.jmb.2007.01.042  1
2006 Melton-Witt JA, Bentsen LM, Tweten RK. Identification of functional domains of Clostridium septicum alpha toxin. Biochemistry. 45: 14347-54. PMID 17128973 DOI: 10.1021/bi061334p  1
2006 Salles II, Voth DE, Ward SC, Averette KM, Tweten RK, Bradley KA, Ballard JD. Cytotoxic activity of Bacillus anthracis protective antigen observed in a macrophage cell line overexpressing ANTXR1. Cellular Microbiology. 8: 1272-81. PMID 16882031 DOI: 10.1111/j.1462-5822.2006.00708.x  1
2006 Giddings KS, Johnson AE, Tweten RK. Perfringolysin O and intermedilysin. Mechanisms of pore formation by the cholesterol-dependent cytolysins The Comprehensive Sourcebook of Bacterial Protein Toxins. 671-679. DOI: 10.1016/B978-012088445-2/50043-3  1
2006 Polekhina G, Feil SC, Tang J, Parker MW, Rossjohn J, Giddings KS, Tweten RK. Comparative three-dimensional structure of cholesterol-dependent cytolysins The Comprehensive Sourcebook of Bacterial Protein Toxins. 659-670. DOI: 10.1016/B978-012088445-2/50042-1  1
2006 Melton J, Tweten RK. Clostridium septicum pore-forming α-toxin The Comprehensive Sourcebook of Bacterial Protein Toxins. 623-630. DOI: 10.1016/B978-012088445-2/50039-1  1
2005 Dang TX, Milligan RA, Tweten RK, Wilson-Kubalek EM. Helical crystallization on nickel-lipid nanotubes: perfringolysin O as a model protein. Journal of Structural Biology. 152: 129-39. PMID 16242343 DOI: 10.1016/j.jsb.2005.07.010  1
2005 Tweten RK. Cholesterol-dependent cytolysins, a family of versatile pore-forming toxins. Infection and Immunity. 73: 6199-209. PMID 16177291 DOI: 10.1128/IAI.73.10.6199-6209.2005  1
2005 Schuerch DW, Wilson-Kubalek EM, Tweten RK. Molecular basis of listeriolysin O pH dependence. Proceedings of the National Academy of Sciences of the United States of America. 102: 12537-42. PMID 16105950 DOI: 10.1073/pnas.0500558102  1
2005 Ramachandran R, Tweten RK, Johnson AE. The domains of a cholesterol-dependent cytolysin undergo a major FRET-detected rearrangement during pore formation. Proceedings of the National Academy of Sciences of the United States of America. 102: 7139-44. PMID 15878993 DOI: 10.1073/pnas.0500556102  1
2005 Dang TX, Hotze EM, Rouiller I, Tweten RK, Wilson-Kubalek EM. Prepore to pore transition of a cholesterol-dependent cytolysin visualized by electron microscopy. Journal of Structural Biology. 150: 100-8. PMID 15797734 DOI: 10.1016/j.jsb.2005.02.003  1
2005 Zheng Z, Tweten RK, Mensa-Wilmot K. Intracellular glycosylphosphatidylinositols accumulate on endosomes: toxicity of alpha-toxin to Leishmania major. Eukaryotic Cell. 4: 556-66. PMID 15755918 DOI: 10.1128/EC.4.3.556-566.2005  1
2005 Polekhina G, Giddings KS, Tweten RK, Parker MW. Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin. Proceedings of the National Academy of Sciences of the United States of America. 102: 600-5. PMID 15637162 DOI: 10.1073/pnas.0403229101  1
2004 Giddings KS, Zhao J, Sims PJ, Tweten RK. Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin. Nature Structural & Molecular Biology. 11: 1173-8. PMID 15543155 DOI: 10.1038/nsmb862  1
2004 Czajkowsky DM, Hotze EM, Shao Z, Tweten RK. Vertical collapse of a cytolysin prepore moves its transmembrane beta-hairpins to the membrane. The Embo Journal. 23: 3206-15. PMID 15297878 DOI: 10.1038/sj.emboj.7600350  1
2004 Zheng Z, Butler KD, Tweten RK, Mensa-Wilmot K. Endosomes, glycosomes, and glycosylphosphatidylinositol catabolism in Leishmania major. The Journal of Biological Chemistry. 279: 42106-13. PMID 15254033 DOI: 10.1074/jbc.M403780200  1
2004 Ramachandran R, Tweten RK, Johnson AE. Membrane-dependent conformational changes initiate cholesterol-dependent cytolysin oligomerization and intersubunit beta-strand alignment. Nature Structural & Molecular Biology. 11: 697-705. PMID 15235590 DOI: 10.1038/nsmb793  1
2004 Polekhina G, Giddings KS, Tweten RK, Parker MW. Crystallization and preliminary X-ray analysis of the human-specific toxin intermedilysin. Acta Crystallographica. Section D, Biological Crystallography. 60: 347-9. PMID 14747721 DOI: 10.1107/S0907444903027240  1
2004 Melton JA, Parker MW, Rossjohn J, Buckley JT, Tweten RK. The identification and structure of the membrane-spanning domain of the Clostridium septicum alpha toxin. The Journal of Biological Chemistry. 279: 14315-22. PMID 14715670 DOI: 10.1074/jbc.M313758200  1
2003 Mourez M, Yan M, Lacy DB, Dillon L, Bentsen L, Marpoe A, Maurin C, Hotze E, Wigelsworth D, Pimental RA, Ballard JD, Collier RJ, Tweten RK. Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 100: 13803-8. PMID 14623961 DOI: 10.1073/pnas.2436299100  1
2003 Giddings KS, Johnson AE, Tweten RK. Redefining cholesterol's role in the mechanism of the cholesterol-dependent cytolysins. Proceedings of the National Academy of Sciences of the United States of America. 100: 11315-20. PMID 14500900 DOI: 10.1073/pnas.2033520100  1
2003 Heuck AP, Tweten RK, Johnson AE. Assembly and topography of the prepore complex in cholesterol-dependent cytolysins. The Journal of Biological Chemistry. 278: 31218-25. PMID 12777381 DOI: 10.1074/jbc.M303151200  1
2002 Ramachandran R, Heuck AP, Tweten RK, Johnson AE. Structural insights into the membrane-anchoring mechanism of a cholesterol-dependent cytolysin. Nature Structural Biology. 9: 823-7. PMID 12368903 DOI: 10.1038/nsb855  1
2002 Wichroski MJ, Melton JA, Donahue CG, Tweten RK, Ward GE. Clostridium septicum alpha-toxin is active against the parasitic protozoan Toxoplasma gondii and targets members of the SAG family of glycosylphosphatidylinositol-anchored surface proteins. Infection and Immunity. 70: 4353-61. PMID 12117945 DOI: 10.1128/IAI.70.8.4353-4361.2002  1
2002 Hotze EM, Heuck AP, Czajkowsky DM, Shao Z, Johnson AE, Tweten RK. Monomer-monomer interactions drive the prepore to pore conversion of a beta-barrel-forming cholesterol-dependent cytolysin. The Journal of Biological Chemistry. 277: 11597-605. PMID 11799121 DOI: 10.1074/jbc.M111039200  1
2001 Heuck AP, Tweten RK, Johnson AE. Beta-barrel pore-forming toxins: intriguing dimorphic proteins. Biochemistry. 40: 9065-73. PMID 11478872 DOI: 10.1021/bi0155394  1
2001 Tweten RK. Clostridium perfringens beta toxin and Clostridium septicum alpha toxin: their mechanisms and possible role in pathogenesis. Veterinary Microbiology. 82: 1-9. PMID 11423190 DOI: 10.1016/S0378-1135(01)00372-8  1
2001 Tweten RK, Parker MW, Johnson AE. The cholesterol-dependent cytolysins. Current Topics in Microbiology and Immunology. 257: 15-33. PMID 11417120  1
2001 Hotze EM, Wilson-Kubalek EM, Rossjohn J, Parker MW, Johnson AE, Tweten RK. Arresting pore formation of a cholesterol-dependent cytolysin by disulfide trapping synchronizes the insertion of the transmembrane beta-sheet from a prepore intermediate. The Journal of Biological Chemistry. 276: 8261-8. PMID 11102453 DOI: 10.1074/jbc.M009865200  1
2000 Heuck AP, Hotze EM, Tweten RK, Johnson AE. Mechanism of membrane insertion of a multimeric beta-barrel protein: perfringolysin O creates a pore using ordered and coupled conformational changes. Molecular Cell. 6: 1233-42. PMID 11106760  1
2000 Shatursky O, Bayles R, Rogers M, Jost BH, Songer JG, Tweten RK. Clostridium perfringens beta-toxin forms potential-dependent, cation-selective channels in lipid bilayers. Infection and Immunity. 68: 5546-51. PMID 10992452 DOI: 10.1128/IAI.68.10.5546-5551.2000  1
2000 Shepard LA, Shatursky O, Johnson AE, Tweten RK. The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins. Biochemistry. 39: 10284-93. PMID 10956018 DOI: 10.1021/bi000436r  1
1999 Shatursky O, Heuck AP, Shepard LA, Rossjohn J, Parker MW, Johnson AE, Tweten RK. The mechanism of membrane insertion for a cholesterol-dependent cytolysin: a novel paradigm for pore-forming toxins. Cell. 99: 293-9. PMID 10555145 DOI: 10.1016/S0092-8674(00)81660-8  1
1999 Gordon VM, Nelson KL, Buckley JT, Stevens VL, Tweten RK, Elwood PC, Leppla SH. Clostridium septicum alpha toxin uses glycosylphosphatidylinositol-anchored protein receptors. The Journal of Biological Chemistry. 274: 27274-80. PMID 10480947 DOI: 10.1074/jbc.274.38.27274  1
1999 Diep DB, Nelson KL, Lawrence TS, Sellman BR, Tweten RK, Buckley JT. Expression and properties of an aerolysin--Clostridium septicum alpha toxin hybrid protein. Molecular Microbiology. 31: 785-94. PMID 10048023 DOI: 10.1046/j.1365-2958.1999.01217.x  1
1998 Gilbert RJ, Rossjohn J, Parker MW, Tweten RK, Morgan PJ, Mitchell TJ, Errington N, Rowe AJ, Andrew PW, Byron O. Self-interaction of pneumolysin, the pore-forming protein toxin of Streptococcus pneumoniae. Journal of Molecular Biology. 284: 1223-37. PMID 9837740 DOI: 10.1006/jmbi.1998.2258  1
1998 Rossjohn J, Gilbert RJ, Crane D, Morgan PJ, Mitchell TJ, Rowe AJ, Andrew PW, Paton JC, Tweten RK, Parker MW. The molecular mechanism of pneumolysin, a virulence factor from Streptococcus pneumoniae. Journal of Molecular Biology. 284: 449-61. PMID 9813129 DOI: 10.1006/jmbi.1998.2167  1
1998 Shepard LA, Heuck AP, Hamman BD, Rossjohn J, Parker MW, Ryan KR, Johnson AE, Tweten RK. Identification of a membrane-spanning domain of the thiol-activated pore-forming toxin Clostridium perfringens perfringolysin O: an alpha-helical to beta-sheet transition identified by fluorescence spectroscopy. Biochemistry. 37: 14563-74. PMID 9772185 DOI: 10.1021/bi981452f  1
1997 Gordon VM, Benz R, Fujii K, Leppla SH, Tweten RK. Clostridium septicum alpha-toxin is proteolytically activated by furin. Infection and Immunity. 65: 4130-4. PMID 9317018  1
1997 Sellman BR, Tweten RK. The propeptide of Clostridium septicum alpha toxin functions as an intramolecular chaperone and is a potent inhibitor of alpha toxin-dependent cytolysis. Molecular Microbiology. 25: 429-40. PMID 9302006  1
1997 Stevens DL, Tweten RK, Awad MM, Rood JI, Bryant AE. Clostridial gas gangrene: evidence that alpha and theta toxins differentially modulate the immune response and induce acute tissue necrosis. The Journal of Infectious Diseases. 176: 189-95. PMID 9207366  1
1997 Rossjohn J, Feil SC, McKinstry WJ, Tweten RK, Parker MW. Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form. Cell. 89: 685-92. PMID 9182756  1
1997 Sellman BR, Kagan BL, Tweten RK. Generation of a membrane-bound, oligomerized pre-pore complex is necessary for pore formation by Clostridium septicum alpha toxin. Molecular Microbiology. 23: 551-8. PMID 9044288  1
1996 Feil SC, Rossjohn J, Rohde K, Tweten RK, Parker MW. Crystallization and preliminary X-ray analysis of a thiol-activated cytolysin. Febs Letters. 397: 290-2. PMID 8955365 DOI: 10.1016/S0014-5793(96)01200-8  1
1995 Ballard J, Crabtree J, Roe BA, Tweten RK. The primary structure of Clostridium septicum alpha-toxin exhibits similarity with that of Aeromonas hydrophila aerolysin. Infection and Immunity. 63: 340-4. PMID 7806374  1
1995 Asmuth DM, Olson RD, Hackett SP, Bryant AE, Tweten RK, Tso JY, Zollman T, Stevens DL. Effects of Clostridium perfringens recombinant and crude phospholipase C and theta-toxin on rabbit hemodynamic parameters. The Journal of Infectious Diseases. 172: 1317-23. PMID 7594670 DOI: 10.1093/infdis/172.5.1317  1
1995 Gottschalk S, Tweten RK, Smith LC, Woo SL. Efficient gene delivery and expression in mammalian cells using DNA coupled with perfringolysin O. Gene Therapy. 2: 498-503. PMID 7584129  1
1994 Johnson S, Driks MR, Tweten RK, Ballard J, Stevens DL, Anderson DJ, Janoff EN. Clinical courses of seven survivors of Clostridium septicum infection and their immunologic responses to alpha toxin. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 19: 761-4. PMID 7803645 DOI: 10.1093/clinids/19.4.761  1
1993 Ballard J, Sokolov Y, Yuan WL, Kagan BL, Tweten RK. Activation and mechanism of Clostridium septicum alpha toxin. Molecular Microbiology. 10: 627-34. PMID 7968539  1
1993 Bryant AE, Bergstrom R, Zimmerman GA, Salyer JL, Hill HR, Tweten RK, Sato H, Stevens DL. Clostridium perfringens invasiveness is enhanced by effects of theta toxin upon PMNL structure and function: the roles of leukocytotoxicity and expression of CD11/CD18 adherence glycoprotein. Fems Immunology and Medical Microbiology. 7: 321-36. PMID 7907907  1
1992 Portnoy DA, Tweten RK, Kehoe M, Bielecki J. Capacity of listeriolysin O, streptolysin O, and perfringolysin O to mediate growth of Bacillus subtilis within mammalian cells. Infection and Immunity. 60: 2710-7. PMID 1612739  1
1992 Ballard J, Bryant A, Stevens D, Tweten RK. Purification and characterization of the lethal toxin (alpha-toxin) of Clostridium septicum. Infection and Immunity. 60: 784-90. PMID 1541552  1
1991 Tweten RK, Harris RW, Sims PJ. Isolation of a tryptic fragment from Clostridium perfringens theta-toxin that contains sites for membrane binding and self-aggregation. The Journal of Biological Chemistry. 266: 12449-54. PMID 2061320  1
1991 Harris RW, Sims PJ, Tweten RK. Evidence that Clostridium perfringens theta-toxin induces colloid-osmotic lysis of erythrocytes. Infection and Immunity. 59: 2499-501. PMID 2050414  1
1991 Harris RW, Sims PJ, Tweten RK. Kinetic aspects of the aggregation of Clostridium perfringens theta-toxin on erythrocyte membranes. A fluorescence energy transfer study. The Journal of Biological Chemistry. 266: 6936-41. PMID 2016307  1
1988 Meador J, Tweten RK. Purification and characterization of toxin B from Clostridium difficile. Infection and Immunity. 56: 1708-14. PMID 3384474  1
1988 Iandolo JJ, Tweten RK. Purification of staphylococcal enterotoxins. Methods in Enzymology. 165: 43-52. PMID 3231117  1
1988 Tweten RK. Nucleotide sequence of the gene for perfringolysin O (theta-toxin) from Clostridium perfringens: significant homology with the genes for streptolysin O and pneumolysin. Infection and Immunity. 56: 3235-40. PMID 2903128  1
1988 Tweten RK. Cloning and expression in Escherichia coli of the perfringolysin O (theta-toxin) gene from Clostridium perfringens and characterization of the gene product. Infection and Immunity. 56: 3228-34. PMID 2903127  1
1985 Christianson KK, Tweten RK, Iandolo JJ. Transport and processing of staphylococcal enterotoxin A. Applied and Environmental Microbiology. 50: 696-7. PMID 4073896  1
1984 Gill SR, Fedorka-Cray PJ, Tweten RK, Sleeper BP. Purification and properties of the carbonic anhydrase of Rhodospirillum rubrum Archives of Microbiology. 138: 113-118. DOI: 10.1007/BF00413010  1
1983 Tweten RK, Iandolo JJ. Transport and processing of staphylococcal enterotoxin B. Journal of Bacteriology. 153: 297-303. PMID 6848484  1
1983 Tweten RK, Christianson KK, Iandolo JJ. Transport and processing of staphylococcal alpha-toxin. Journal of Bacteriology. 156: 524-8. PMID 6630145  1
1983 Tweten RK, Collier RJ. Molecular cloning and expression of gene fragments from corynebacteriophage beta encoding enzymatically active peptides of diphtheria toxin. Journal of Bacteriology. 156: 680-5. PMID 6313613  1
1983 Wen L, Tweten RK, Isackson PJ, Iandolo JJ, Reeck GR. Ionic interactions between proteins in nonequilibrium pH gradient electrophoresis: histones affect the migration of high mobility group nonhistone chromatin proteins. Analytical Biochemistry. 132: 294-304. PMID 6226213 DOI: 10.1016/0003-2697(83)90011-8  1
1981 Tweten RK, Iandolo JJ. Purification and partial characterization of a putative precursor to staphylococcal enterotoxin B. Infection and Immunity. 34: 900-7. PMID 7333675  1
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