John B. MacMillan, Ph.D. - Publications

Affiliations: 
2008- Chemistry University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
Natural Products isolation from cyanobacteria
Website:
http://www.utsouthwestern.edu/labs/macmillan/

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 McMillan EA, Kwon G, Clemenceau JR, Fisher KW, Vaden RM, Shaikh AF, Neilsen BK, Kelly D, Potts MB, Sung YJ, Mendiratta S, Hight SK, Lee Y, MacMillan JB, Lewis RE, et al. A Genome-wide Functional Signature Ontology Map and Applications to Natural Product Mechanism of Action Discovery. Cell Chemical Biology. PMID 31378711 DOI: 10.1016/j.chembiol.2019.07.008  0.6
2018 McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, et al. Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports. PMID 30468235 DOI: 10.1039/c8np90041h  1
2018 Nichols BA, Oswald NW, McMillan EA, McGlynn K, Yan J, Kim MS, Saha J, Mallipeddi PL, LaDuke SA, Villalobos PA, Rodriguez-Canales J, Wistuba II, Posner BA, Davis AJ, Minna JD, ... MacMillan JB, et al. HORMAD1 is a negative prognostic indicator in lung adenocarcinoma and specifies resistance to oxidative and genotoxic stress. Cancer Research. PMID 30185546 DOI: 10.1158/0008-5472.CAN-18-1377  0.64
2018 McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, et al. The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports. PMID 30003207 DOI: 10.1039/c7np00064b  1
2018 Wang C, Niederstrasser H, Douglas PM, Lin R, Jaramillo J, Li Y, Oswald NW, Zhou A, McMillan EA, Mendiratta S, Wang Z, Zhao T, Lin Z, Luo M, Huang G, ... ... MacMillan JB, et al. Author Correction: Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan. Nature Communications. 9: 2050. PMID 29784984 DOI: 10.1038/s41467-018-04519-8  0.64
2018 McMillan EA, Ryu MJ, Diep CH, Mendiratta S, Clemenceau JR, Vaden RM, Kim JH, Motoyaji T, Covington KR, Peyton M, Huffman K, Wu X, Girard L, Sung Y, Chen PH, ... ... MacMillan JB, et al. Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer. Cell. PMID 29681454 DOI: 10.1016/j.cell.2018.03.028  0.64
2018 Das B, Neilsen BK, Fisher KW, Gehring D, Hu Y, Volle DJ, Kim HS, McCall JL, Kelly DL, MacMillan JB, White MA, Lewis RE. A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells. Scientific Reports. 8: 3770. PMID 29491475 DOI: 10.1038/s41598-018-22090-6  1
2017 Wang C, Niederstrasser H, Douglas PM, Lin R, Jaramillo J, Li Y, Olswald NW, Zhou A, McMillan EA, Mendiratta S, Wang Z, Zhao T, Lin Z, Luo M, Huang G, ... ... MacMillan JB, et al. Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan. Nature Communications. 8: 2270. PMID 29273768 DOI: 10.1038/s41467-017-02332-3  0.64
2017 Kalwat MA, Wichaidit C, Nava Garcia AY, McCoy MK, McGlynn K, Hwang IH, MacMillan JB, Posner BA, Cobb MH. Correction to Insulin Promoter-Driven Gaussia Luciferase-Based Insulin Secretion Biosensor Assay for Discovery of β-Cell Glucose-Sensing Pathways. Acs Sensors. 2: 316. PMID 28723136 DOI: 10.1021/acssensors.7b00012  0.64
2017 Fu P, MacMillan JB. Carpatizine, a novel bridged oxazine derivative generated by non-enzymatic reactions. Organic & Biomolecular Chemistry. PMID 28620660 DOI: 10.1039/c7ob01178d  1
2017 Vaden RM, Oswald NW, Potts MB, MacMillan JB, White MA. FUSION-Guided Hypothesis Development Leads to the Identification of N⁶,N⁶-Dimethyladenosine, a Marine-Derived AKT Pathway Inhibitor. Marine Drugs. 15. PMID 28294973 DOI: 10.3390/md15030075  0.64
2017 Fu P, La S, MacMillan JB. Daryamide Analogues from a Marine-Derived Streptomyces species. Journal of Natural Products. PMID 28225277 DOI: 10.1021/acs.jnatprod.7b00011  1
2016 Colosimo DA, MacMillan JB. Ammosamides Unveil Novel Biosynthetic Machinery. Cell Chemical Biology. 23: 1444-1446. PMID 28009976 DOI: 10.1016/j.chembiol.2016.12.001  1
2016 Kalwat MA, Wichaidit C, Nava Garcia AY, McCoy MK, McGlynn K, Hwang IH, MacMillan JB, Posner BA, Cobb MH. Insulin promoter-driven Gaussia luciferase-based insulin secretion biosensor assay for discovery of β-cell glucose-sensing pathways. Acs Sensors. 1: 1208-1212. PMID 27819058 DOI: 10.1021/acssensors.6b00433  0.64
2016 Seitz T, Fu P, Haut FL, Adam L, Habicht M, Lentz D, MacMillan JB, Christmann M. One-Pot Synthesis of 5-Hydroxy-4H-1,3-thiazin-4-ones: Structure Revision, Synthesis, and NMR Shift Dependence of Thiasporine A. Organic Letters. PMID 27286418 DOI: 10.1021/acs.orglett.6b01166  1
2016 Feng Y, Liu J, Carrasco YP, MacMillan JB, De Brabander JK. Rifamycin Biosynthetic Congeners: Isolation and Total Synthesis of Rifsaliniketal and Total Synthesis of Salinisporamycin and Saliniketals A and B. Journal of the American Chemical Society. PMID 27232659 DOI: 10.1021/jacs.6b03248  0.4
2016 Sato S, Jung H, Nakagawa T, Pawlosky R, Takeshima T, Lee WR, Sakiyama H, Laxman S, Wynn RM, Tu B, MacMillan JB, De Brabander JK, Veech RL, Uyeda K. Metabolite Regulation of Nuclear Localization of Carbohydrate Response Element-binding Protein (ChREBP). Role of AMP as an Allosteric Inhibitor. The Journal of Biological Chemistry. PMID 26984404 DOI: 10.1074/jbc.M115.708982  1
2016 Fu P, Legako A, La S, MacMillan JB. Discovery, Characterization, and Analogue Synthesis of Bohemamine Dimers Generated by Non-enzymatic Biosynthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26834079 DOI: 10.1002/chem.201600024  1
2016 Colosimo DA, MacMillan JB. Detailed Mechanistic Study of the Non-enzymatic Formation of the Discoipyrrole Family of Natural Products. Journal of the American Chemical Society. PMID 26824832 DOI: 10.1021/jacs.5b13320  1
2015 Chen J, Koswatta P, DeBergh JR, Fu P, Pan E, MacMillan JB, Ready JM. Structure Elucidation of Nigricanoside A Through Enantioselective Total Synthesis. Chemical Science (Royal Society of Chemistry : 2010). 6: 2932-2937. PMID 26877863 DOI: 10.1039/C5SC00281H  1
2015 Fu P, La S, MacMillan JB. 1,3-Oxazin-6-one Derivatives and Bohemamine-Type Pyrrolizidine Alkaloids from a Marine-Derived Streptomyces spinoverrucosus. Journal of Natural Products. PMID 26489038 DOI: 10.1021/acs.jnatprod.5b00604  1
2015 Fisher KW, Das B, Kim HS, Clymer BK, Gehring D, Smith D, Costanzo-Garvey D, Fernandez M, Brattain MG, Kelly D, MacMillan J, White MA, Lewis RE. AMPK promotes aberrant PGC1β expression to support human colon tumor cell survival. Molecular and Cellular Biology. PMID 26351140 DOI: 10.1128/MCB.00528-15  1
2015 Scheuermann TH, Stroud D, Sleet CE, Bayeh L, Shokri C, Wang H, Caldwell CG, Longgood J, MacMillan JB, Bruick RK, Gardner KH, Tambar UK. Isoform-Selective and Stereoselective Inhibition of Hypoxia Inducible Factor-2. Journal of Medicinal Chemistry. PMID 26226049 DOI: 10.1021/acs.jmedchem.5b00529  1
2015 Korotkov A, Li H, Chapman CW, Xue H, MacMillan JB, Eastman A, Wu J. Total Syntheses and Biological Evaluation of Both Enantiomers of Several Hydroxylated Dimeric Nuphar Alkaloids. Angewandte Chemie (International Ed. in English). PMID 26205039 DOI: 10.1002/anie.201503934  1
2015 Fu P, MacMillan JB. Spithioneines A and B, Two New Bohemamine Derivatives Possessing Ergothioneine Moiety from a Marine-Derived Streptomyces spinoverrucosus. Organic Letters. 17: 3046-9. PMID 26024315 DOI: 10.1021/acs.orglett.5b01328  1
2015 Potts MB, McMillan EA, Rosales TI, Kim HS, Ou YH, Toombs JE, Brekken RA, Minden MD, MacMillan JB, White MA. Mode of action and pharmacogenomic biomarkers for exceptional responders to didemnin B. Nature Chemical Biology. 11: 401-8. PMID 25867045 DOI: 10.1038/nchembio.1797  1
2015 Nguyen Y, Nguyen NX, Rogers JL, Liao J, MacMillan JB, Jiang Y, Sperandio V. Structural and mechanistic roles of novel chemical ligands on the SdiA quorum-sensing transcription regulator. Mbio. 6. PMID 25827420 DOI: 10.1128/mBio.02429-14  1
2015 Fu P, MacMillan JB. Thiasporines A-C, thiazine and thiazole derivatives from a marine-derived Actinomycetospora chlora. Journal of Natural Products. 78: 548-51. PMID 25584783 DOI: 10.1021/np500929z  1
2015 Chen J, Koswatta P, DeBergh JR, Fu P, Pan E, MacMillan JB, Ready JM. Structure elucidation of nigricanoside A through enantioselective total synthesis Chemical Science. 6: 2932-2937. DOI: 10.1039/c5sc00281h  1
2015 Fu P, Macmillan JB. Thiasporines A-C, thiazine and thiazole derivatives from a marine-derived actinomycetospora chlora Journal of Natural Products. 78: 548-551. DOI: 10.1021/np500929z  1
2015 Fu P, Macmillan JB. Spithioneines A and B, Two New Bohemamine Derivatives Possessing Ergothioneine Moiety from a Marine-Derived Streptomyces spinoverrucosus Organic Letters. 17: 3046-3049. DOI: 10.1021/acs.orglett.5b01328  1
2014 Fu P, Jamison M, La S, MacMillan JB. Inducamides A-C, chlorinated alkaloids from an RNA polymerase mutant strain of Streptomyces sp. Organic Letters. 16: 5656-5659. PMID 25338006 DOI: 10.1021/ol502731p  1
2014 Fu P, Johnson M, Chen H, Posner BA, MacMillan JB. Carpatamides A-C, cytotoxic arylamine derivatives from a marine-derived streptomyces sp. Journal of Natural Products. 77: 1245-1248. PMID 24754815 DOI: 10.1021/np500207p  1
2014 Derebe MG, Zlatkov CM, Gattu S, Ruhn KA, Vaishnava S, Diehl GE, MacMillan JB, Williams NS, Hooper LV. Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection Elife. 3: 1-18. DOI: 10.7554/eLife.03206  1
2013 Potts MB, Kim HS, Fisher KW, Hu Y, Carrasco YP, Bulut GB, Ou YH, Herrera-Herrera ML, Cubillos F, Mendiratta S, Xiao G, Hofree M, Ideker T, Xie Y, Huang LJ, ... ... MacMillan JB, et al. Using functional signature ontology (FUSION) to identify mechanisms of action for natural products. Science Signaling. 6: ra90. PMID 24129700 DOI: 10.1126/scisignal.2004657  1
2013 Hu Y, Potts MB, Colosimo D, Herrera-Herrera ML, Legako AG, Yousufuddin M, White MA, MacMillan JB. Discoipyrroles A-D: Isolation, structure determination, and synthesis of potent migration inhibitors from Bacillus hunanensis Journal of the American Chemical Society. 135: 13387-13392. PMID 23984625 DOI: 10.1021/ja403412y  1
2013 Rogers JL, Bayeh L, Scheuermann TH, Longgood J, Key J, Naidoo J, Melito L, Shokri C, Frantz DE, Bruick RK, Gardner KH, MacMillan JB, Tambar UK. Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor. Journal of Medicinal Chemistry. 56: 1739-47. PMID 23363003 DOI: 10.1021/jm301847z  1
2013 Hu Y, Wang K, MacMillan JB. Hunanamycin A, an antibiotic from a marine-derived Bacillus hunanensis Organic Letters. 15: 390-393. PMID 23305153 DOI: 10.1021/ol303376c  1
2013 Sun Q, Carrasco YP, Hu Y, Guo X, Mirzaei H, Macmillan J, Chook YM. Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proceedings of the National Academy of Sciences of the United States of America. 110: 1303-8. PMID 23297231 DOI: 10.1073/pnas.1217203110  1
2013 Pan E, Oswald NW, Legako AG, Life JM, Posner BA, Macmillan JB. Precursor-Directed Generation of Amidine Containing Ammosamide Analogs: Ammosamides E-P. Chemical Science (Royal Society of Chemistry : 2010). 4: 482-488. PMID 23209870 DOI: 10.1039/C2SC21442C  0.88
2013 Pan E, Oswald NW, Legako AG, Life JM, Posner BA, MacMillan JB. Precursor-directed generation of amidine containing ammosamide analogs: Ammosamides E-P Chemical Science. 4: 482-488. DOI: 10.1039/c2sc21442c  1
2012 Hu Y, Martinez ED, MacMillan JB. Anthraquinones from a marine-derived streptomyces spinoverrucosus Journal of Natural Products. 75: 1759-1764. PMID 23057874 DOI: 10.1021/np3004326  1
2012 Rogers JL, MacMillan JB. A labeled substrate approach to discovery of biocatalytic reactions: a proof of concept transformation with N-methylindole. Journal of the American Chemical Society. 134: 12378-81. PMID 22809085 DOI: 10.1021/ja304767m  1
2012 Pan E, Jamison M, Yousufuddin M, MacMillan JB. Ammosamide D, an oxidatively ring opened ammosamide analog from a marine-derived Streptomyces variabilis Organic Letters. 14: 2390-2393. PMID 22515470 DOI: 10.1021/ol300806e  1
2012 Hu Y, MacMillan JB. A new peptide isolated from a marine derived Streptomyces bacillaris Natural Product Communications. 7: 211-214. PMID 22474960  1
2012 Hu Y, Legako AG, Espindola APDM, MacMillan JB. Erythrolic acids A-E, meroterpenoids from a marine-derived erythrobacter sp. Journal of Organic Chemistry. 77: 3401-3407. PMID 22384985 DOI: 10.1021/jo300197z  1
2011 Hu Y, MacMillan JB. Erythrazoles A-B, cytotoxic benzothiazoles from a marine-derived erythrobacter sp. Organic Letters. 13: 6580-6583. PMID 22106936 DOI: 10.1021/ol202944g  1
2011 Hu Y, Espindola APDM, Stewart NA, Wei S, Posner BA, MacMillan JB. Chromomycin SA analogs from a marine-derived Streptomyces sp. Bioorganic and Medicinal Chemistry. 19: 5183-5189. PMID 21807523 DOI: 10.1016/j.bmc.2011.07.013  1
2010 Schreiber SL, Shamji AF, Clemons PA, Hon C, Koehler AN, Munoz B, Palmer M, Stern AM, Wagner BK, Powers S, Lowe SW, Guo X, Krasnitz A, Sawey ET, ... ... MacMillan JB, et al. Towards patient-based cancer therapeutics. Nature Biotechnology. 28: 904-6. PMID 20829823 DOI: 10.1038/nbt0910-904  1
2009 Maloney KN, MacMillan JB, Kauffman CA, Jensen PR, Dipasquale AG, Rheingold AL, Fenical W. Lodopyridone, a structurally unprecedented alkaloid from a marine actinomycete Organic Letters. 11: 5422-5424. PMID 19883103 DOI: 10.1021/ol901997k  1
2009 Espindola AP, Crouch R, DeBergh JR, Ready JM, MacMillan JB. Deconvolution of complex NMR spectra in small molecules by multi frequency homonuclear decoupling (MDEC). Journal of the American Chemical Society. 131: 15994-5. PMID 19845379 DOI: 10.1021/ja907110e  1
2009 Chiu YH, MacMillan JB, Chen ZJ. RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway Cell. 138: 576-591. PMID 19631370 DOI: 10.1016/j.cell.2009.06.015  1
2009 Hughes CC, MacMillan JB, Gaudêncio SP, Fenical W, La Clair JJ. Ammosamides A and B target myosin Angewandte Chemie - International Edition. 48: 728-732. PMID 19097126 DOI: 10.1002/anie.200804107  1
2009 Hughes CC, MacMillan JB, Gaudêncio SP, Jensen PR, Fenical W. The ammosamides: Structures of cell cycle modulators from a marine-derived Streptomyces species Angewandte Chemie - International Edition. 48: 725-727. PMID 19090514 DOI: 10.1002/anie.200804890  1
2008 Newton GL, Jensen PR, Macmillan JB, Fenical W, Fahey RC. An N-acyl homolog of mycothiol is produced in marine actinomycetes. Archives of Microbiology. 190: 547-57. PMID 18629474 DOI: 10.1007/s00203-008-0405-3  1
2008 MacMillan JB, Xiong-Zhou G, Skepper CK, Molinski TF. Phorbasides A-E, cytotoxic chlorocyclopropane macrolide glycosides from the marine sponge Phorbas sp. CD determination of C-methyl sugar configurations. The Journal of Organic Chemistry. 73: 3699-706. PMID 18412387 DOI: 10.1021/jo702307t  1
2007 Skepper CK, Macmillan JB, Zhou GX, Masuno MN, Molinski TF. Chlorocyclopropane macrolides from the marine sponge Phorbas sp. assignment of the configurations of phorbasides A and B by quantitative CD. Journal of the American Chemical Society. 129: 4150-1. PMID 17373800 DOI: 10.1021/ja0703978  1
2006 Cueto M, MacMillan JB, Jensen PR, Fenical W. Tropolactones A-D, four meroterpenoids from a marine-derived fungus of the genus Aspergillus Phytochemistry. 67: 1826-1831. PMID 16500687 DOI: 10.1016/j.phytochem.2006.01.008  1
2006 Linington RG, Robertson M, Gauthier A, Finlay BB, MacMillan JB, Molinski TF, van Soest R, Andersen RJ. Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconia. Journal of Natural Products. 69: 173-7. PMID 16499312 DOI: 10.1021/np050192h  1
2005 Makarieva TN, Denisenko VA, Dmitrenok PS, Guzii AG, Santalova EA, Stonik VA, Macmillan JB, Molinski TF. Oceanalin A, a hybrid alpha,omega-bifunctionalized sphingoid tetrahydroisoquinoline beta-glycoside from the marine sponge Oceanapia sp. Organic Letters. 7: 2897-900. PMID 15987164 DOI: 10.1021/ol050796c  1
2005 Macmillan JB, Molinski TF. Majusculoic acid, a brominated cyclopropyl fatty acid from a marine cyanobacterial mat assemblage. Journal of Natural Products. 68: 604-6. PMID 15844960 DOI: 10.1021/np049596k  1
2004 Kossuga MH, MacMillan JB, Rogers EW, Molinski TF, Nascimento GG, Rocha RM, Berlinck RG. (2S,3R)-2-aminododecan-3-ol, a new antifungal agent from the ascidian Clavelina oblonga. Journal of Natural Products. 67: 1879-81. PMID 15568780 DOI: 10.1021/np049782q  1
2004 Liu C, Masuno MN, Macmillan JB, Molinski TF. Enantioselective total synthesis of (+)-milnamide A and evidence of its autoxidation to (+)-milnamide D. Angewandte Chemie (International Ed. in English). 43: 5951-4. PMID 15547903 DOI: 10.1002/anie.200461245  1
2004 Macmillan JB, Linington RG, Andersen RJ, Molinski TF. Stereochemical assignment in acyclic lipids across long distance by circular dichroism: absolute stereochemistry of the aglycone of caminoside A. Angewandte Chemie (International Ed. in English). 43: 5946-51. PMID 15547902 DOI: 10.1002/anie.200461158  1
2004 MacMillan JB, Molinski TF. Long-range stereo-relay: relative and absolute configuration of 1,n-glycols from circular dichroism of liposomal porphyrin esters. Journal of the American Chemical Society. 126: 9944-5. PMID 15303868 DOI: 10.1021/ja047741a  1
2002 MacMillan JB, Ernst-Russell MA, de Ropp JS, Molinski TF. Lobocyclamides A-C, lipopeptides from a cryptic cyanobacterial mat containing Lyngbya confervoides. The Journal of Organic Chemistry. 67: 8210-5. PMID 12423153 DOI: 10.1021/jo0261909  1
2002 Nicholas GM, Li R, MacMillan JB, Molinski TF. Antifungal activity of bifunctional sphingolipids. Intramolecular synergism within long-chain alpha,omega-bis-aminoalcohols. Bioorganic & Medicinal Chemistry Letters. 12: 2159-62. PMID 12127527 DOI: 10.1016/S0960-894X(02)00367-0  1
2002 MacMillan JB, Molinski TF. Lobocyclamide B from Lyngbya confervoides. Configuration and asymmetric synthesis of beta-hydroxy-alpha-amino acids by (-)-sparteine-mediated aldol addition. Organic Letters. 4: 1883-6. PMID 12027638 DOI: 10.1021/ol025876k  1
2002 MacMillan JB, Molinski TF. Caylobolide A, a unique 36-membered macrolactone from a Bahamian Lyngbya majuscula. Organic Letters. 4: 1535-8. PMID 11975622 DOI: 10.1021/ol025759p  1
2002 Moon SS, MacMillan JB, Olmstead MM, Ta TA, Pessah IN, Molinski TF. (+)-7S-Hydroxyxestospongin A from the marine sponge Xestospongia sp. and absolute configuration of (+)-xestospongin D. Journal of Natural Products. 65: 249-54. PMID 11908959 DOI: 10.1021/np010427z  1
2000 MacMillan JB, Trousdale EK, Molinski TF. Structure of (-)-neodysidenin from Dysidea herbacea. Implications for biosynthesis of 5,5,5-trichloroleucine peptides. Organic Letters. 2: 2721-3. PMID 10990437  1
2000 MacMillan JB, Molinski TF. Herbacic acid, a simple prototype of 5,5,5-trichloroleucine metabolites from the sponge Dysidea herbacea. Journal of Natural Products. 63: 155-7. PMID 10650102 DOI: 10.1021/np990468j  1
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