John B. MacMillan, Ph.D. - Publications

Affiliations: 
2008- Chemistry University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
Natural Products isolation from cyanobacteria
Website:
http://www.utsouthwestern.edu/labs/macmillan/

71/137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Khadilkar A, Bunch ZL, Wagoner J, Ravindran V, Oda JM, Vidar WS, Clark TN, Manwill PK, Todd DA, Barr SA, Olinger LK, Fink SL, Strangman WK, Linington RG, MacMillan JB, et al. Modulation of SARS-CoV-2 Infection by and Its Alkaloid Constituents. Journal of Natural Products. PMID 37043739 DOI: 10.1021/acs.jnatprod.3c00159  0.779
2022 Hight SK, Clark TN, Kurita KL, McMillan EA, Bray W, Shaikh AF, Khadilkar A, Haeckl FPJ, Carnevale-Neto F, La S, Lohith A, Vaden RM, Lee J, Wei S, Lokey RS, ... ... MacMillan JB, et al. High-throughput functional annotation of natural products by integrated activity profiling. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208458119. PMID 36449542 DOI: 10.1073/pnas.2208458119  0.708
2022 Bouthillette LM, Aniebok V, Colosimo DA, Brumley D, MacMillan JB. Nonenzymatic Reactions in Natural Product Formation. Chemical Reviews. PMID 36006409 DOI: 10.1021/acs.chemrev.2c00306  0.758
2022 Aniebok V, Shingare R, Wei-Lee H, Johnstone T, MacMillan J. Biomimetic Total Synthesis and Investigation of the Non-Enzymatic Chemistry of Oxazinin A. Angewandte Chemie (International Ed. in English). PMID 35881566 DOI: 10.1002/anie.202208029  0.798
2022 Shingare RD, MacMillan JB, Reddy DS. Antibiotic natural product hunanamycin A: Lead identification towards anti-Salmonella agents. European Journal of Medicinal Chemistry. 236: 114245. PMID 35421661 DOI: 10.1016/j.ejmech.2022.114245  0.788
2021 Trebino MA, Shingare RD, MacMillan JB, Yildiz FH. Strategies and Approaches for Discovery of Small Molecule Disruptors of Biofilm Physiology. Molecules (Basel, Switzerland). 26. PMID 34361735 DOI: 10.3390/molecules26154582  0.757
2020 Dhaneesha M, Umar M, Merlin TS, Krishnan KP, Sukumaran V, Sinha RK, Anas A, Fu P, MacMillan JB, Sajeevan TP. Pseudonocardia cytotoxica sp. nov., a novel actinomycete isolated from an Arctic fjord with potential to produce cytotoxic compound. Antonie Van Leeuwenhoek. PMID 33230720 DOI: 10.1007/s10482-020-01490-7  0.469
2020 Shingare RD, Aniebok V, Lee HW, MacMillan JB. Synthesis and Investigation of the Abiotic Formation of Pyonitrins A-D. Organic Letters. PMID 32017580 DOI: 10.1021/Acs.Orglett.0C00098  0.805
2019 McMillan EA, Kwon G, Clemenceau JR, Fisher KW, Vaden RM, Shaikh AF, Neilsen BK, Kelly D, Potts MB, Sung YJ, Mendiratta S, Hight SK, Lee Y, MacMillan JB, Lewis RE, et al. A Genome-wide Functional Signature Ontology Map and Applications to Natural Product Mechanism of Action Discovery. Cell Chemical Biology. PMID 31378711 DOI: 10.1016/J.Chembiol.2019.07.008  0.576
2019 Gong J, Li W, Fu P, MacMillan J, De Brabander JK. Isolation, Structure, and Total Synthesis of the Marine Macrolide Mangrolide D. Organic Letters. PMID 30957503 DOI: 10.1021/Acs.Orglett.9B01126  0.588
2018 McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, et al. Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports. PMID 30468235 DOI: 10.1039/c8np90041h  0.721
2018 McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, et al. The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports. PMID 30003207 DOI: 10.1039/C7Np00064B  0.733
2018 Das B, Neilsen BK, Fisher KW, Gehring D, Hu Y, Volle DJ, Kim HS, McCall JL, Kelly DL, MacMillan JB, White MA, Lewis RE. A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells. Scientific Reports. 8: 3770. PMID 29491475 DOI: 10.1038/S41598-018-22090-6  0.635
2017 Wang C, Niederstrasser H, Douglas PM, Lin R, Jaramillo J, Li Y, Olswald NW, Zhou A, McMillan EA, Mendiratta S, Wang Z, Zhao T, Lin Z, Luo M, Huang G, ... ... MacMillan JB, et al. Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan. Nature Communications. 8: 2270. PMID 29273768 DOI: 10.1038/S41467-017-02332-3  0.305
2017 Fu P, MacMillan JB. Carpatizine, a novel bridged oxazine derivative generated by non-enzymatic reactions. Organic & Biomolecular Chemistry. PMID 28620660 DOI: 10.1039/C7Ob01178D  0.577
2017 Vaden RM, Oswald NW, Potts MB, MacMillan JB, White MA. FUSION-Guided Hypothesis Development Leads to the Identification of N⁶,N⁶-Dimethyladenosine, a Marine-Derived AKT Pathway Inhibitor. Marine Drugs. 15. PMID 28294973 DOI: 10.3390/Md15030075  0.417
2017 Fu P, La S, MacMillan JB. Daryamide Analogues from a Marine-Derived Streptomyces species. Journal of Natural Products. PMID 28225277 DOI: 10.1021/Acs.Jnatprod.7B00011  0.58
2016 Colosimo DA, MacMillan JB. Ammosamides Unveil Novel Biosynthetic Machinery. Cell Chemical Biology. 23: 1444-1446. PMID 28009976 DOI: 10.1016/J.Chembiol.2016.12.001  0.788
2016 Seitz T, Fu P, Haut FL, Adam L, Habicht M, Lentz D, MacMillan JB, Christmann M. One-Pot Synthesis of 5-Hydroxy-4H-1,3-thiazin-4-ones: Structure Revision, Synthesis, and NMR Shift Dependence of Thiasporine A. Organic Letters. PMID 27286418 DOI: 10.1021/Acs.Orglett.6B01166  0.571
2016 Feng Y, Liu J, Carrasco YP, MacMillan JB, De Brabander JK. Rifamycin Biosynthetic Congeners: Isolation and Total Synthesis of Rifsaliniketal and Total Synthesis of Salinisporamycin and Saliniketals A and B. Journal of the American Chemical Society. PMID 27232659 DOI: 10.1021/Jacs.6B03248  0.801
2016 Fu P, Legako A, La S, MacMillan JB. Discovery, Characterization, and Analogue Synthesis of Bohemamine Dimers Generated by Non-enzymatic Biosynthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26834079 DOI: 10.1002/Chem.201600024  0.592
2016 Colosimo DA, MacMillan JB. Detailed Mechanistic Study of the Non-enzymatic Formation of the Discoipyrrole Family of Natural Products. Journal of the American Chemical Society. PMID 26824832 DOI: 10.1021/Jacs.5B13320  0.796
2015 Chen J, Koswatta P, DeBergh JR, Fu P, Pan E, MacMillan JB, Ready JM. Structure Elucidation of Nigricanoside A Through Enantioselective Total Synthesis. Chemical Science (Royal Society of Chemistry : 2010). 6: 2932-2937. PMID 26877863 DOI: 10.1039/C5Sc00281H  0.812
2015 Fu P, La S, MacMillan JB. 1,3-Oxazin-6-one Derivatives and Bohemamine-Type Pyrrolizidine Alkaloids from a Marine-Derived Streptomyces spinoverrucosus. Journal of Natural Products. PMID 26489038 DOI: 10.1021/Acs.Jnatprod.5B00604  0.563
2015 Korotkov A, Li H, Chapman CW, Xue H, MacMillan JB, Eastman A, Wu J. Total Syntheses and Biological Evaluation of Both Enantiomers of Several Hydroxylated Dimeric Nuphar Alkaloids. Angewandte Chemie (International Ed. in English). PMID 26205039 DOI: 10.1002/Anie.201503934  0.393
2015 Fu P, MacMillan JB. Spithioneines A and B, Two New Bohemamine Derivatives Possessing Ergothioneine Moiety from a Marine-Derived Streptomyces spinoverrucosus. Organic Letters. 17: 3046-9. PMID 26024315 DOI: 10.1021/Acs.Orglett.5B01328  0.606
2015 Potts MB, McMillan EA, Rosales TI, Kim HS, Ou YH, Toombs JE, Brekken RA, Minden MD, MacMillan JB, White MA. Mode of action and pharmacogenomic biomarkers for exceptional responders to didemnin B. Nature Chemical Biology. 11: 401-8. PMID 25867045 DOI: 10.1038/Nchembio.1797  0.305
2015 Fu P, MacMillan JB. Thiasporines A-C, thiazine and thiazole derivatives from a marine-derived Actinomycetospora chlora. Journal of Natural Products. 78: 548-51. PMID 25584783 DOI: 10.1021/Np500929Z  0.577
2015 McMillan E, DeSevo C, Oswald N, Hanson J, Chen P, Deberardinis R, Williams N, MacMillan J, Posner B, White M. Abstract B1-55: Predictive modeling of drug sensitivity in non-small cell lung cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-B1-55  0.321
2015 Oswald N, McMillan E, Posner B, White M, MacMillan J. Modeling cellular responses in non-small cell lung cancer using marine derived natural products Planta Medica. 81. DOI: 10.1055/S-0035-1556355  0.306
2015 Colosimo D, Cai F, Hu Y, Potts M, White M, Ready J, MacMillan J. The discoipyrroles: A multifaceted approach to understand a novel family of marine natural products Planta Medica. 81. DOI: 10.1055/S-0035-1556348  0.642
2015 Chen J, Koswatta P, DeBergh JR, Fu P, Pan E, MacMillan JB, Ready JM. Structure elucidation of nigricanoside A through enantioselective total synthesis Chemical Science. 6: 2932-2937. DOI: 10.1039/c5sc00281h  0.779
2015 Fu P, Macmillan JB. Thiasporines A-C, thiazine and thiazole derivatives from a marine-derived actinomycetospora chlora Journal of Natural Products. 78: 548-551. DOI: 10.1021/np500929z  0.433
2015 Fu P, Macmillan JB. Spithioneines A and B, Two New Bohemamine Derivatives Possessing Ergothioneine Moiety from a Marine-Derived Streptomyces spinoverrucosus Organic Letters. 17: 3046-3049. DOI: 10.1021/acs.orglett.5b01328  0.478
2014 Fu P, Jamison M, La S, MacMillan JB. Inducamides A-C, chlorinated alkaloids from an RNA polymerase mutant strain of Streptomyces sp. Organic Letters. 16: 5656-5659. PMID 25338006 DOI: 10.1021/Ol502731P  0.78
2014 Fu P, Johnson M, Chen H, Posner BA, MacMillan JB. Carpatamides A-C, cytotoxic arylamine derivatives from a marine-derived streptomyces sp. Journal of Natural Products. 77: 1245-1248. PMID 24754815 DOI: 10.1021/Np500207P  0.553
2013 Potts MB, Kim HS, Fisher KW, Hu Y, Carrasco YP, Bulut GB, Ou YH, Herrera-Herrera ML, Cubillos F, Mendiratta S, Xiao G, Hofree M, Ideker T, Xie Y, Huang LJ, ... ... MacMillan JB, et al. Using functional signature ontology (FUSION) to identify mechanisms of action for natural products. Science Signaling. 6: ra90. PMID 24129700 DOI: 10.1126/Scisignal.2004657  0.773
2013 Hu Y, Potts MB, Colosimo D, Herrera-Herrera ML, Legako AG, Yousufuddin M, White MA, MacMillan JB. Discoipyrroles A-D: Isolation, structure determination, and synthesis of potent migration inhibitors from Bacillus hunanensis Journal of the American Chemical Society. 135: 13387-13392. PMID 23984625 DOI: 10.1021/Ja403412Y  0.791
2013 Hu Y, Wang K, MacMillan JB. Hunanamycin A, an antibiotic from a marine-derived Bacillus hunanensis Organic Letters. 15: 390-393. PMID 23305153 DOI: 10.1021/Ol303376C  0.686
2013 Sun Q, Carrasco YP, Hu Y, Guo X, Mirzaei H, Macmillan J, Chook YM. Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proceedings of the National Academy of Sciences of the United States of America. 110: 1303-8. PMID 23297231 DOI: 10.1073/Pnas.1217203110  0.776
2013 Pan E, Oswald NW, Legako AG, Life JM, Posner BA, Macmillan JB. Precursor-Directed Generation of Amidine Containing Ammosamide Analogs: Ammosamides E-P. Chemical Science (Royal Society of Chemistry : 2010). 4: 482-488. PMID 23209870 DOI: 10.1039/C2Sc21442C  0.787
2012 Hu Y, Martinez ED, MacMillan JB. Anthraquinones from a marine-derived streptomyces spinoverrucosus Journal of Natural Products. 75: 1759-1764. PMID 23057874 DOI: 10.1021/Np3004326  0.678
2012 Rogers JL, MacMillan JB. A labeled substrate approach to discovery of biocatalytic reactions: a proof of concept transformation with N-methylindole. Journal of the American Chemical Society. 134: 12378-81. PMID 22809085 DOI: 10.1021/Ja304767M  0.33
2012 Pan E, Jamison M, Yousufuddin M, MacMillan JB. Ammosamide D, an oxidatively ring opened ammosamide analog from a marine-derived Streptomyces variabilis Organic Letters. 14: 2390-2393. PMID 22515470 DOI: 10.1021/Ol300806E  0.778
2012 Hu Y, MacMillan JB. A new peptide isolated from a marine derived Streptomyces bacillaris Natural Product Communications. 7: 211-214. PMID 22474960 DOI: 10.1177/1934578X1200700224  0.667
2012 Hu Y, Legako AG, Espindola APDM, MacMillan JB. Erythrolic acids A-E, meroterpenoids from a marine-derived erythrobacter sp. Journal of Organic Chemistry. 77: 3401-3407. PMID 22384985 DOI: 10.1021/Jo300197Z  0.681
2011 Hu Y, MacMillan JB. Erythrazoles A-B, cytotoxic benzothiazoles from a marine-derived erythrobacter sp. Organic Letters. 13: 6580-6583. PMID 22106936 DOI: 10.1021/Ol202944G  0.657
2011 Hu Y, Espindola APDM, Stewart NA, Wei S, Posner BA, MacMillan JB. Chromomycin SA analogs from a marine-derived Streptomyces sp. Bioorganic and Medicinal Chemistry. 19: 5183-5189. PMID 21807523 DOI: 10.1016/J.Bmc.2011.07.013  0.692
2009 Maloney KN, MacMillan JB, Kauffman CA, Jensen PR, Dipasquale AG, Rheingold AL, Fenical W. Lodopyridone, a structurally unprecedented alkaloid from a marine actinomycete Organic Letters. 11: 5422-5424. PMID 19883103 DOI: 10.1021/Ol901997K  0.532
2009 Espindola AP, Crouch R, DeBergh JR, Ready JM, MacMillan JB. Deconvolution of complex NMR spectra in small molecules by multi frequency homonuclear decoupling (MDEC). Journal of the American Chemical Society. 131: 15994-5. PMID 19845379 DOI: 10.1021/Ja907110E  0.767
2009 Hughes CC, MacMillan JB, Gaudêncio SP, Fenical W, La Clair JJ. Ammosamides A and B target myosin Angewandte Chemie - International Edition. 48: 728-732. PMID 19097126 DOI: 10.1002/Anie.200804107  0.496
2009 Hughes CC, MacMillan JB, Gaudêncio SP, Jensen PR, Fenical W. The ammosamides: Structures of cell cycle modulators from a marine-derived Streptomyces species Angewandte Chemie - International Edition. 48: 725-727. PMID 19090514 DOI: 10.1002/Anie.200804890  0.578
2008 Newton GL, Jensen PR, Macmillan JB, Fenical W, Fahey RC. An N-acyl homolog of mycothiol is produced in marine actinomycetes. Archives of Microbiology. 190: 547-57. PMID 18629474 DOI: 10.1007/S00203-008-0405-3  0.525
2008 MacMillan JB, Xiong-Zhou G, Skepper CK, Molinski TF. Phorbasides A-E, cytotoxic chlorocyclopropane macrolide glycosides from the marine sponge Phorbas sp. CD determination of C-methyl sugar configurations. The Journal of Organic Chemistry. 73: 3699-706. PMID 18412387 DOI: 10.1021/Jo702307T  0.779
2008 Gaudêncio S, MacMillan J, Jensen P, Fenical W. Ammosamides A and B new cytotoxic alkaloids isolated from a marine Streptomyces sp Planta Medica. 74. DOI: 10.1055/S-0028-1084516  0.521
2007 Skepper CK, Macmillan JB, Zhou GX, Masuno MN, Molinski TF. Chlorocyclopropane macrolides from the marine sponge Phorbas sp. assignment of the configurations of phorbasides A and B by quantitative CD. Journal of the American Chemical Society. 129: 4150-1. PMID 17373800 DOI: 10.1021/Ja0703978  0.756
2006 Cueto M, MacMillan JB, Jensen PR, Fenical W. Tropolactones A-D, four meroterpenoids from a marine-derived fungus of the genus Aspergillus Phytochemistry. 67: 1826-1831. PMID 16500687 DOI: 10.1016/J.Phytochem.2006.01.008  0.559
2006 Linington RG, Robertson M, Gauthier A, Finlay BB, MacMillan JB, Molinski TF, van Soest R, Andersen RJ. Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconia. Journal of Natural Products. 69: 173-7. PMID 16499312 DOI: 10.1021/Np050192H  0.688
2005 Makarieva TN, Denisenko VA, Dmitrenok PS, Guzii AG, Santalova EA, Stonik VA, Macmillan JB, Molinski TF. Oceanalin A, a hybrid alpha,omega-bifunctionalized sphingoid tetrahydroisoquinoline beta-glycoside from the marine sponge Oceanapia sp. Organic Letters. 7: 2897-900. PMID 15987164 DOI: 10.1021/Ol050796C  0.691
2005 Macmillan JB, Molinski TF. Majusculoic acid, a brominated cyclopropyl fatty acid from a marine cyanobacterial mat assemblage. Journal of Natural Products. 68: 604-6. PMID 15844960 DOI: 10.1021/Np049596K  0.664
2004 Kossuga MH, MacMillan JB, Rogers EW, Molinski TF, Nascimento GG, Rocha RM, Berlinck RG. (2S,3R)-2-aminododecan-3-ol, a new antifungal agent from the ascidian Clavelina oblonga. Journal of Natural Products. 67: 1879-81. PMID 15568780 DOI: 10.1021/Np049782Q  0.769
2004 Liu C, Masuno MN, Macmillan JB, Molinski TF. Enantioselective total synthesis of (+)-milnamide A and evidence of its autoxidation to (+)-milnamide D. Angewandte Chemie (International Ed. in English). 43: 5951-4. PMID 15547903 DOI: 10.1002/Anie.200461245  0.776
2004 Macmillan JB, Linington RG, Andersen RJ, Molinski TF. Stereochemical assignment in acyclic lipids across long distance by circular dichroism: absolute stereochemistry of the aglycone of caminoside A. Angewandte Chemie (International Ed. in English). 43: 5946-51. PMID 15547902 DOI: 10.1002/Anie.200461158  0.628
2004 MacMillan JB, Molinski TF. Long-range stereo-relay: relative and absolute configuration of 1,n-glycols from circular dichroism of liposomal porphyrin esters. Journal of the American Chemical Society. 126: 9944-5. PMID 15303868 DOI: 10.1021/Ja047741A  0.648
2002 MacMillan JB, Ernst-Russell MA, de Ropp JS, Molinski TF. Lobocyclamides A-C, lipopeptides from a cryptic cyanobacterial mat containing Lyngbya confervoides. The Journal of Organic Chemistry. 67: 8210-5. PMID 12423153 DOI: 10.1021/Jo0261909  0.682
2002 Nicholas GM, Li R, MacMillan JB, Molinski TF. Antifungal activity of bifunctional sphingolipids. Intramolecular synergism within long-chain alpha,omega-bis-aminoalcohols. Bioorganic & Medicinal Chemistry Letters. 12: 2159-62. PMID 12127527 DOI: 10.1016/S0960-894X(02)00367-0  0.648
2002 MacMillan JB, Molinski TF. Lobocyclamide B from Lyngbya confervoides. Configuration and asymmetric synthesis of beta-hydroxy-alpha-amino acids by (-)-sparteine-mediated aldol addition. Organic Letters. 4: 1883-6. PMID 12027638 DOI: 10.1021/Ol025876K  0.667
2002 MacMillan JB, Molinski TF. Caylobolide A, a unique 36-membered macrolactone from a Bahamian Lyngbya majuscula. Organic Letters. 4: 1535-8. PMID 11975622 DOI: 10.1021/Ol025759P  0.679
2002 Moon SS, MacMillan JB, Olmstead MM, Ta TA, Pessah IN, Molinski TF. (+)-7S-Hydroxyxestospongin A from the marine sponge Xestospongia sp. and absolute configuration of (+)-xestospongin D. Journal of Natural Products. 65: 249-54. PMID 11908959 DOI: 10.1021/Np010427Z  0.671
2000 MacMillan JB, Trousdale EK, Molinski TF. Structure of (-)-neodysidenin from Dysidea herbacea. Implications for biosynthesis of 5,5,5-trichloroleucine peptides. Organic Letters. 2: 2721-3. PMID 10990437 DOI: 10.1021/Ol006326U  0.665
2000 MacMillan JB, Molinski TF. Herbacic acid, a simple prototype of 5,5,5-trichloroleucine metabolites from the sponge Dysidea herbacea. Journal of Natural Products. 63: 155-7. PMID 10650102 DOI: 10.1021/Np990468J  0.668
Low-probability matches (unlikely to be authored by this person)
2015 Nguyen Y, Nguyen NX, Rogers JL, Liao J, MacMillan JB, Jiang Y, Sperandio V. Structural and mechanistic roles of novel chemical ligands on the SdiA quorum-sensing transcription regulator. Mbio. 6. PMID 25827420 DOI: 10.1128/Mbio.02429-14  0.295
2013 Rogers JL, Bayeh L, Scheuermann TH, Longgood J, Key J, Naidoo J, Melito L, Shokri C, Frantz DE, Bruick RK, Gardner KH, MacMillan JB, Tambar UK. Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor. Journal of Medicinal Chemistry. 56: 1739-47. PMID 23363003 DOI: 10.1021/Jm301847Z  0.291
2018 Minna JD, McMillan E, Girard L, Peyton M, Huffman K, Deb D, Yenerall P, Das A, Li L, Dalvi M, Gao B, Xie Y, Yu Y, Hight S, Vaden R, ... ... MacMillan J, et al. Abstract IA12: Developing precision medicine-based new lung cancer therapeutics Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-Ia12  0.288
2014 Das B, Fisher K, Kim H, Volle DJ, Smith DR, Livergood RS, MacMillan J, White M, Lewis R. Abstract A07: Novel effectors of K-Ras-mediated and KSR1 dependent colon tumorigenesis Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-A07  0.286
2014 Minna JD, Gazdar A, Augustyn A, Britt R, Carstens R, Dospoy P, Gao B, Girard L, Hight S, Huffman K, Larsen J, Peyton M, Shao C, Mangelsdorf D, Brekken R, ... ... MacMillan J, et al. Abstract IA21: Developing a new functional classification of lung cancer based on tumor acquired vulnerabilities. Clinical Cancer Research. 20: IA21-IA21. DOI: 10.1158/1078-0432.14Aacriaslc-Ia21  0.286
2020 Luesch H, MacMillan JB. Targeting and extending the eukaryotic druggable genome with natural products. Natural Product Reports. 37: 744-746. PMID 32525143 DOI: 10.1039/D0Np90021D  0.281
2018 McMillan EA, Ryu MJ, Diep CH, Mendiratta S, Clemenceau JR, Vaden RM, Kim JH, Motoyaji T, Covington KR, Peyton M, Huffman K, Wu X, Girard L, Sung Y, Chen PH, ... ... MacMillan JB, et al. Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer. Cell. PMID 29681454 DOI: 10.1016/J.Cell.2018.03.028  0.28
2015 Hing ZA, Fung HYJ, Ranganathan P, Mitchell S, El-Gamal D, Woyach JA, Williams K, Goettl VM, Smith JL, Yu X, Meng X, Sun Q, Cagatay T, MacMillan JB, Lehman AM, et al. Next Generation XPO1 Inhibitor Shows Improved Efficacy and In Vivo Tolerability in Hematologic Malignancies Blood. 126: 317-317. DOI: 10.1182/Blood.V126.23.317.317  0.28
2011 Bruick RK, Gardner KH, MacMillan J, Tambar U. Modulation of HIF-2 Function with Small Molecules: Did Nature Beat Us to It? Blood. 118: SCI-39-SCI-39. DOI: 10.1182/Blood.V118.21.Sci-39.Sci-39  0.279
2016 Gerhard DS, Clemons PA, Shamji AF, Hon C, Wagner BK, Schreiber SL, Krasnitz A, Sordella R, Sander C, Lowe SW, Powers S, Smith K, Aburi M, Iavarone A, Lasorella A, ... ... MacMillan J, et al. Transforming Big Data into cancer-relevant insight: An initial, multi-tier approach to assess reproducibility and relevance. Molecular Cancer Research : McR. PMID 27401613 DOI: 10.1158/1541-7786.Mcr-16-0090  0.274
2016 Sato S, Jung H, Nakagawa T, Pawlosky R, Takeshima T, Lee WR, Sakiyama H, Laxman S, Wynn RM, Tu B, MacMillan JB, De Brabander JK, Veech RL, Uyeda K. Metabolite Regulation of Nuclear Localization of Carbohydrate Response Element-binding Protein (ChREBP). Role of AMP as an Allosteric Inhibitor. The Journal of Biological Chemistry. PMID 26984404 DOI: 10.1074/Jbc.M115.708982  0.268
2016 Li B, Lowe-Power T, Kurihara S, Gonzales SS, Naidoo J, MacMillan JB, Allen C, Michael A. Functional Identification of Putrescine C- and N-Hydroxylases. Acs Chemical Biology. PMID 27541336 DOI: 10.1021/Acschembio.6B00629  0.262
2010 Schreiber SL, Shamji AF, Clemons PA, Hon C, Koehler AN, Munoz B, Palmer M, Stern AM, Wagner BK, Powers S, Lowe SW, Guo X, Krasnitz A, Sawey ET, ... ... MacMillan JB, et al. Towards patient-based cancer therapeutics. Nature Biotechnology. 28: 904-6. PMID 20829823 DOI: 10.1038/Nbt0910-904  0.261
2015 Scheuermann TH, Stroud D, Sleet CE, Bayeh L, Shokri C, Wang H, Caldwell CG, Longgood J, MacMillan JB, Bruick RK, Gardner KH, Tambar UK. Isoform-Selective and Stereoselective Inhibition of Hypoxia Inducible Factor-2. Journal of Medicinal Chemistry. PMID 26226049 DOI: 10.1021/Acs.Jmedchem.5B00529  0.261
2018 Nichols BA, Oswald NW, McMillan EA, McGlynn K, Yan J, Kim MS, Saha J, Mallipeddi PL, LaDuke SA, Villalobos PA, Rodriguez-Canales J, Wistuba II, Posner BA, Davis AJ, Minna JD, ... MacMillan JB, et al. HORMAD1 is a negative prognostic indicator in lung adenocarcinoma and specifies resistance to oxidative and genotoxic stress. Cancer Research. PMID 30185546 DOI: 10.1158/0008-5472.Can-18-1377  0.25
2020 Kumar A, Russell RM, Pifer R, Menezes-Garcia Z, Cuesta S, Narayanan S, MacMillan JB, Sperandio V. The Serotonin Neurotransmitter Modulates Virulence of Enteric Pathogens. Cell Host & Microbe. PMID 32521224 DOI: 10.1016/J.Chom.2020.05.004  0.25
2022 Macho JM, Blue RM, Lee HW, MacMillan JB. Boron NMR as a Method to Screen Natural Product Libraries for B-Containing Compounds. Organic Letters. PMID 35472262 DOI: 10.1021/acs.orglett.2c00885  0.246
2016 Kalwat MA, Wichaidit C, Nava Garcia AY, McCoy MK, McGlynn K, Hwang IH, MacMillan JB, Posner BA, Cobb MH. Insulin promoter-driven Gaussia luciferase-based insulin secretion biosensor assay for discovery of β-cell glucose-sensing pathways. Acs Sensors. 1: 1208-1212. PMID 27819058 DOI: 10.1021/Acssensors.6B00433  0.244
2022 Blue RM, Macho JM, Lee HW, MacMillan JB. B and H-B HMBC NMR as a Tool for Identification of a Boron-Containing Nucleoside Dimer. Journal of Natural Products. PMID 36343012 DOI: 10.1021/acs.jnatprod.2c00745  0.243
2015 Fisher KW, Das B, Kim HS, Clymer BK, Gehring D, Smith D, Costanzo-Garvey D, Fernandez M, Brattain MG, Kelly D, MacMillan J, White MA, Lewis RE. AMPK promotes aberrant PGC1β expression to support human colon tumor cell survival. Molecular and Cellular Biology. PMID 26351140 DOI: 10.1128/Mcb.00528-15  0.243
2014 Derebe MG, Zlatkov CM, Gattu S, Ruhn KA, Vaishnava S, Diehl GE, MacMillan JB, Williams NS, Hooper LV. Biochemical and structural analysis reveals a retinol binding function for serum amyloid A proteins Elife. DOI: 10.2210/Pdb4Q5G/Pdb  0.242
2020 Sorkin BC, Kuszak AJ, Bloss G, Fukagawa NK, Hoffman FA, Jafari M, Barrett B, Brown PN, Bushman FD, Casper SJ, Chilton FH, Coffey CS, Ferruzzi MG, Hopp DC, Kiely M, ... ... MacMillan JB, et al. Improving natural product research translation: From source to clinical trial. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 34: 41-65. PMID 31914647 DOI: 10.1096/Fj.201902143R  0.239
2018 Kalwat MA, Hwang IH, Macho J, Grzemska MG, Yang JZ, McGlynn K, MacMillan JB, Cobb MH. Chromomycin A potently inhibits glucose-stimulated insulin secretion from pancreatic β cells. The Journal of General Physiology. PMID 30352794 DOI: 10.1085/Jgp.201812177  0.234
2014 Derebe MG, Zlatkov CM, Gattu S, Ruhn KA, Vaishnava S, Diehl GE, MacMillan JB, Williams NS, Hooper LV. Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection. Elife. 3: e03206. PMID 25073702 DOI: 10.7554/Elife.03206  0.228
2009 Chiu YH, MacMillan JB, Chen ZJ. RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway Cell. 138: 576-591. PMID 19631370 DOI: 10.1016/J.Cell.2009.06.015  0.227
2018 Wang C, Niederstrasser H, Douglas PM, Lin R, Jaramillo J, Li Y, Oswald NW, Zhou A, McMillan EA, Mendiratta S, Wang Z, Zhao T, Lin Z, Luo M, Huang G, ... ... MacMillan JB, et al. Author Correction: Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan. Nature Communications. 9: 2050. PMID 29784984 DOI: 10.1038/S41467-018-04519-8  0.217
2014 Derebe MG, Zlatkov CM, Gattu S, Ruhn KA, Vaishnava S, Diehl GE, MacMillan JB, Williams NS, Hooper LV. Author response: Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection Elife. DOI: 10.7554/Elife.03206.021  0.199
2013 Craddock K, Young M, Lipe C, Yanes A, Griffiths J, Antanesian R, Brown P, Avalos B, Vukovich C, MacMillan J, Kenyon N, Louie S. Chronic Obstructive Pulmonary Disease Education and Training by Respiratory Care Practitioners Decreases Healthcare Utilization and Improves Patient Outcomes Chest. 144: 543A. DOI: 10.1378/Chest.1703311  0.168
2021 Schwarzer P, Flemming S, MacMillan JB, Bechthold A. Draft Genome Sequence of Marine Actinobacterium Streptomyces spinoverrucosus SNB-032. Microbiology Resource Announcements. 10. PMID 33888496 DOI: 10.1128/MRA.00082-21  0.143
2005 Lea RA, Ovcaric M, Sundholm J, Solyom L, Macmillan J, Griffiths LR. Genetic variants of angiotensin converting enzyme and methylenetetrahydrofolate reductase may act in combination to increase migraine susceptibility. Brain Research. Molecular Brain Research. 136: 112-7. PMID 15893594 DOI: 10.1016/j.molbrainres.2005.01.006  0.087
1997 Smith KM, Macmillan JB, McGrath JC. Investigation of alpha1-adrenoceptor subtypes mediating vasoconstriction in rabbit cutaneous resistance arteries. British Journal of Pharmacology. 122: 825-32. PMID 9384497 DOI: 10.1038/Sj.Bjp.0701451  0.087
1993 MacLean MR, McCulloch KM, MacMillan JB, McGrath JC. Influences of the endothelium and hypoxia on neurogenic transmission in the isolated pulmonary artery of the rabbit. British Journal of Pharmacology. 108: 150-4. PMID 8094022 DOI: 10.1111/J.1476-5381.1993.Tb13455.X  0.082
1989 Templeton AGB, Macmillan J, McGrath JC, Storey ND, Wilson VG. Evidence for prazosin-resistant, rauwolscine-sensitive α-adrenoceptors mediating contractions in the isolated vascular bed of the rat tail British Journal of Pharmacology. 97: 563-571. PMID 2547477 DOI: 10.1111/J.1476-5381.1989.Tb11986.X  0.081
2013 Pan E, Oswald NW, Legako AG, Life JM, Posner BA, MacMillan JB. Precursor-directed generation of amidine containing ammosamide analogs: Ammosamides E-P Chemical Science. 4: 482-488. DOI: 10.1039/c2sc21442c  0.081
1994 Templeton AG, Kingdom JC, Macmillan JB, McGrath JC, Whittle MJ. Atrial natriuretic peptide counteracts the vasoconstrictor effects of 5-hydroxytryptamine, U46619 and endothelin-1 in the human umbilical artery. Placenta. 15: 715-20. PMID 7838827 DOI: 10.1016/0143-4004(94)90034-5  0.071
2005 Colson NJ, Lea RA, Quinlan S, MacMillan J, Griffiths LR. Investigation of hormone receptor genes in migraine. Neurogenetics. 6: 17-23. PMID 15654614 DOI: 10.1007/s10048-004-0205-0  0.065
2008 Smith RA, Curtain R, Ovcaric M, Tajouri L, Macmillan J, Griffiths L. Investigation of the NOTCH3 and TNFSF7 genes on C19p13 as candidates for migraine. The Open Neurology Journal. 2: 1-7. PMID 19018300 DOI: 10.2174/1874205X00802010001  0.061
2015 Peeters K, Bervoets S, Chamova T, Litvinenko I, De Vriendt E, Bichev S, Kancheva D, Mitev V, Kennerson M, Timmerman V, De Jonghe P, Tournev I, MacMillan J, Jordanova A. Novel mutations in the DYNC1H1 tail domain refine the genetic and clinical spectrum of dyneinopathies. Human Mutation. 36: 287-91. PMID 25512093 DOI: 10.1002/Humu.22744  0.061
2020 Lehnert SJ, Baillie SM, MacMillan J, Paterson IG, Buhariwalla CF, Bradbury IR, Bentzen P. Multiple decades of stocking has resulted in limited hatchery introgression in wild brook trout () populations of Nova Scotia. Evolutionary Applications. 13: 1069-1089. PMID 32431753 DOI: 10.1111/Eva.12923  0.061
2021 Chang T, Draper JM, Van den Bout A, Kephart E, Maul-Newby H, Vasquez Y, Woodbury J, Randi S, Pedersen M, Nave M, La S, Gallagher N, McCabe MM, Dhillon N, Bjork I, ... ... MacMillan JB, et al. A method for campus-wide SARS-CoV-2 surveillance at a large public university. Plos One. 16: e0261230. PMID 34919584 DOI: 10.1371/journal.pone.0261230  0.052
2004 Lea RA, Ovcaric M, Sundholm J, MacMillan J, Griffiths LR. The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura. Bmc Medicine. 2: 3. PMID 15053827 DOI: 10.1186/1741-7015-2-3  0.052
2016 Ruzzante DE, McCracken GR, Parmelee S, Hill K, Corrigan A, MacMillan J, Walde SJ. Effective number of breeders, effective population size and their relationship with census size in an iteroparous species, Salvelinus fontinalis. Proceedings. Biological Sciences / the Royal Society. 283. PMID 26817773 DOI: 10.1098/rspb.2015.2601  0.051
1999 Smith KM, Macmillan JB, McCulloch KM, McGrath JC. NOS inhibition potentiates norepinephrine but not sympathetic nerve-mediated co-transmission in resistance arteries. Cardiovascular Research. 43: 762-71. PMID 10690348 DOI: 10.1016/S0008-6363(99)00092-9  0.048
1952 SOMMERVILLE J, MACMILLAN JB. The treatment of essential hyperidrosis with hexamethonium bromide; a preliminary report. The British Journal of Dermatology. 64: 442-6. PMID 13009026  0.045
2013 Leblanc R, MacMillan J, Cone D. Timing of appearance of gyrodactylus colemanensis (Monogenea) on young-of-the-year salvelinus fontinalis in a Nova Scotia stream and contribution of these infections to total parasite standing crop Journal of Parasitology. 99: 712-714. PMID 23368772 DOI: 10.1645/12-71.1  0.045
2006 Curtain R, Tajouri L, Lea R, MacMillan J, Griffiths L. No mutations detected in the INSR gene in a chromosome 19p13 linked migraine pedigree European Journal of Medical Genetics. 49: 57-62. PMID 16473310 DOI: 10.1016/j.ejmg.2005.01.015  0.045
2014 Derebe MG, Zlatkov CM, Gattu S, Ruhn KA, Vaishnava S, Diehl GE, MacMillan JB, Williams NS, Hooper LV. Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection Elife. 3: 1-18. DOI: 10.7554/eLife.03206  0.043
1972 Kamath SK, MacMillan JB, Arnrich L. Dietary protein and utilization of carotene or retinyl acetate in rats. The Journal of Nutrition. 102: 1579-84. PMID 4634991  0.042
2004 Colson NJ, Lea RA, Quinlan S, MacMillan J, Griffiths LR. The estrogen receptor 1 G594A polymorphism is associated with migraine susceptibility in two independent case/control groups. Neurogenetics. 5: 129-33. PMID 15133719 DOI: 10.1007/s10048-004-0181-4  0.041
2007 Fernandez F, Curtain RP, Colson NJ, Ovcaric M, MacMillan J, Griffiths LR. Association analysis of chromosome 1 migraine candidate genes Bmc Medical Genetics. 8. PMID 17727731 DOI: 10.1186/1471-2350-8-57  0.039
2005 Curtain R, Sundholm J, Lea R, Ovcaric M, MacMillan J, Griffiths L. Association analysis of a highly polymorphic CAG repeat in the human potassium channel gene KCNN3 and migraine susceptibility Bmc Medical Genetics. 6. PMID 16162291 DOI: 10.1186/1471-2350-6-32  0.034
2009 Lea R, Colson N, Quinlan S, MacMillan J, Griffiths L. The effects of vitamin supplementation and MTHFR (C677T) genotype on homocysteine-lowering and migraine disability Pharmacogenetics and Genomics. 19: 422-428. PMID 19384265 DOI: 10.1097/FPC.0b013e32832af5a3  0.031
2017 Kalwat MA, Wichaidit C, Nava Garcia AY, McCoy MK, McGlynn K, Hwang IH, MacMillan JB, Posner BA, Cobb MH. Correction to Insulin Promoter-Driven Gaussia Luciferase-Based Insulin Secretion Biosensor Assay for Discovery of β-Cell Glucose-Sensing Pathways. Acs Sensors. 2: 316. PMID 28723136 DOI: 10.1021/acssensors.7b00012  0.031
2017 Kelly E, Wu MY, MacMillan JB. Robotic-assisted vesicovaginal fistula repair using an extravesical approach without interposition grafting. Journal of Robotic Surgery. PMID 28353196 DOI: 10.1007/s11701-017-0694-0  0.027
2011 You P, MacMillan J, Cone D. Local patchiness of Gyrodactylus colemanensis and G. salmonis parasitizing salmonids in the South River watershed, Nova Scotia, Canada Diseases of Aquatic Organisms. 96: 137-143. PMID 22013753 DOI: 10.3354/dao02379  0.026
2009 Monsky WL, Yoneda KY, MacMillan J, Deutsch LS, Dong P, Hourigan H, Schwartz Y, Magee S, Duffield C, Boak T, Cernilia J. Peritoneal and pleural ports for management of refractory ascites and pleural effusions: assessment of impact on patient quality of life and hospice/home nursing care. Journal of Palliative Medicine. 12: 811-7. PMID 19622018 DOI: 10.1089/jpm.2009.0061  0.023
2003 Farrell SA, Beckerson LA, Epp A, Flood CG, Lajoie F, MacMillan JB, Mainprize TC, Robert M. Tension-free vaginal tape (TVT) procedure. Journal of Obstetrics and Gynaecology Canada : Jogc = Journal D'Obstã©Trique Et Gynã©Cologie Du Canada : Jogc. 25: 692-4, 695-8. PMID 12908021  0.018
1984 MacMillan JB, Hale RW. Contraction stress testing with mammary self-stimulation. The Journal of Reproductive Medicine. 29: 219-21. PMID 6716364  0.016
2015 Anderson WG, Puntillo K, Boyle D, Barbour S, Turner K, Cimino J, Moore E, Noort J, MacMillan J, Pearson D, Grywalski M, Liao S, Ferrell B, Meyer J, O'Neil-Page E, et al. ICU Bedside Nurses' Involvement in Palliative Care Communication: A Multicenter Survey. Journal of Pain and Symptom Management. PMID 26596882 DOI: 10.1016/J.Jpainsymman.2015.11.003  0.012
2005 Robert M, Farrell SA, Easton WA, Epp A, Flood CG, Girouard L, Lajoie F, MacMillan JB, Mainprize TC. Choice of surgery for stress incontinence. Journal of Obstetrics and Gynaecology Canada : Jogc = Journal D'Obstã©Trique Et Gynã©Cologie Du Canada : Jogc. 27: 964-80. PMID 16411012 DOI: 10.1016/S1701-2163(16)30744-7  0.011
1959 PETERKIN GA, MACMILLAN JB. Unusual eruptions associated with internal malignant disease. Archives of Dermatology. 80: 564-9. PMID 14432176 DOI: 10.1001/archderm.1959.01560230050009  0.011
2021 Macmillan J. On the Treatment of West India Fevers. Edinburgh Medical and Surgical Journal. 10: 30-39. PMID 30329398  0.01
2019 Choo S, Wiseman D, MacMillan JB, Gratton R. Myometrial Defect in a Subsequent Pregnancy After Uterine Artery Embolization for Postpartum Hemorrhage, in the Absence of Leiomyomas or Previous Uterine Surgery. Journal of Obstetrics and Gynaecology Canada : Jogc = Journal D'Obstetrique Et Gynecologie Du Canada : Jogc. PMID 31285167 DOI: 10.1016/j.jogc.2019.04.013  0.01
2017 Anderson WG, Puntillo K, Cimino J, Noort J, Pearson D, Boyle D, Grywalski M, Meyer J, O'Neil-Page E, Cain J, Herman H, Barbour S, Turner K, Moore E, Liao S, ... ... MacMillan J, et al. Palliative Care Professional Development for Critical Care Nurses: A Multicenter Program. American Journal of Critical Care : An Official Publication, American Association of Critical-Care Nurses. 26: 361-371. PMID 28864431 DOI: 10.4037/Ajcc2017336  0.01
2006 MacMillan JB, Drutz HP. Postoperative voiding dysfunction Female Pelvic Medicine and Reconstructive Pelvic Surgery. 497-512. DOI: 10.1007/1-84628-238-1_46  0.01
1962 PETERKIN GA, MACMILLAN JB, MACLEAN S. Pseudocarcinoma of the skin. A follow-up of cases of keratoacanthoma seen in the 10 years 1951-60. Scottish Medical Journal. 7: 27-35. PMID 14485716  0.01
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