William S. Agnew - Publications

Affiliations: 
Yale University School of Medicine, New Haven, CT 
Area:
ion channels
Website:
http://www.physiology.emory.edu/agnew.htm

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2007 Emerick MC, Parmigiani G, Agnew WS. Multivariate analysis and visualization of splicing correlations in single-gene transcriptomes. Bmc Bioinformatics. 8: 16. PMID 17233916 DOI: 10.1186/1471-2105-8-16  1
2006 Emerick MC, Stein R, Kunze R, McNulty MM, Regan MR, Hanck DA, Agnew WS. Profiling the array of Ca(v)3.1 variants from the human T-type calcium channel gene CACNA1G: alternative structures, developmental expression, and biophysical variations. Proteins. 64: 320-42. PMID 16671074 DOI: 10.1002/prot.20877  1
2006 Zhong X, Liu JR, Kyle JW, Hanck DA, Agnew WS. A profile of alternative RNA splicing and transcript variation of CACNA1H, a human T-channel gene candidate for idiopathic generalized epilepsies. Human Molecular Genetics. 15: 1497-512. PMID 16565161 DOI: 10.1093/hmg/ddl068  1
2005 Regan MR, Lin DD, Emerick MC, Agnew WS. The effect of higher order RNA processes on changing patterns of protein domain selection: a developmentally regulated transcriptome of type 1 inositol 1,4,5-trisphosphate receptors. Proteins. 59: 312-31. PMID 15739177 DOI: 10.1002/prot.20225  1
2002 Soong TW, DeMaria CD, Alvania RS, Zweifel LS, Liang MC, Mittman S, Agnew WS, Yue DT. Systematic identification of splice variants in human P/Q-type channel alpha1(2.1) subunits: implications for current density and Ca2+-dependent inactivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10142-52. PMID 12451115  1
2000 Regan MR, Emerick MC, Agnew WS. Full-length single-gene cDNA libraries: applications in splice variant analysis. Analytical Biochemistry. 286: 265-76. PMID 11067749 DOI: 10.1006/abio.2000.4819  1
1999 Mittman S, Guo J, Agnew WS. Structure and alternative splicing of the gene encoding alpha1G, a human brain T calcium channel alpha1 subunit. Neuroscience Letters. 274: 143-6. PMID 10548410 DOI: 10.1016/S0304-3940(99)00716-8  1
1999 Mittman S, Guo J, Emerick MC, Agnew WS. Structure and alternative splicing of the gene encoding alpha1I, a human brain T calcium channel alpha1 subunit. Neuroscience Letters. 269: 121-4. PMID 10454147 DOI: 10.1016/S0304-3940(99)00319-5  1
1997 Bendahhou S, Cummins TR, Agnew WS. Mechanism of modulation of the voltage-gated skeletal and cardiac muscle sodium channels by fatty acids. The American Journal of Physiology. 272: C592-600. PMID 9124303  1
1997 Street VA, Bosma MM, Demas VP, Regan MR, Lin DD, Robinson LC, Agnew WS, Tempel BL. The type 1 inositol 1,4,5-trisphosphate receptor gene is altered in the opisthotonos mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 635-45. PMID 8987786  1
1996 Bendahhou S, Agnew WS. Enhancement of the Shaker B delta6-46 current by fatty acids depends on the activation of the lipoxygenase metabolic pathway. PflüGers Archiv : European Journal of Physiology. 432: 1091-3. PMID 8781205 DOI: 10.1007/s004240050239  1
1995 Bendahhou S, Cummins TR, Potts JF, Tong J, Agnew WS. Serine-1321-independent regulation of the mu 1 adult skeletal muscle Na+ channel by protein kinase C. Proceedings of the National Academy of Sciences of the United States of America. 92: 12003-7. PMID 8618832 DOI: 10.1073/pnas.92.26.12003  1
1994 Stephan MM, Potts JF, Agnew WS. The microI skeletal muscle sodium channel: mutation E403Q eliminates sensitivity to tetrodotoxin but not to mu-conotoxins GIIIA and GIIIB. The Journal of Membrane Biology. 137: 1-8. PMID 7911843 DOI: 10.1007/BF00234993  1
1994 Tong J, Bendahhou S, Chen H, Agnew WS. A simplified method for single-cell RT-PCR that can detect and distinguish genomic DNA and mRNA transcripts. Nucleic Acids Research. 22: 3253-4. PMID 7520571 DOI: 10.1093/nar/22.15.3253  1
1993 Emerick MC, Shenkel S, Agnew WS. Regulation of the eel electroplax Na channel and phosphorylation of residues on amino- and carboxyl-terminal domains by cAMP-dependent protein kinase. Biochemistry. 32: 9435-44. PMID 8396430  1
1993 Cummins TR, Zhou J, Sigworth FJ, Ukomadu C, Stephan M, Ptácek LJ, Agnew WS. Functional consequences of a Na+ channel mutation causing hyperkalemic periodic paralysis. Neuron. 10: 667-78. PMID 8386527 DOI: 10.1016/0896-6273(93)90168-Q  1
1993 Potts JF, Regan MR, Rochelle JM, Seldin MF, Agnew WS. A glial-specific voltage-sensitive Na channel gene maps close to clustered genes for neuronal isoforms on mouse chromosome 2. Biochemical and Biophysical Research Communications. 197: 100-4. PMID 8250913 DOI: 10.1006/bbrc.1993.2446  1
1993 Tong J, Potts JF, Rochelle JM, Seldin MF, Agnew WS. A single B1 subunit mapped to mouse chromosome 7 may be a common component of Na channel isoforms from brain, skeletal muscle and heart. Biochemical and Biophysical Research Communications. 195: 679-85. PMID 7690558 DOI: 10.1006/bbrc.1993.2099  1
1992 Hingorani SR, Agnew WS. Assay and purification of neuronal receptors for inositol 1,4,5-trisphosphate. Methods in Enzymology. 207: 573-91. PMID 1326703  1
1992 Ukomadu C, Zhou J, Sigworth FJ, Agnew WS. muI Na+ channels expressed transiently in human embryonic kidney cells: biochemical and biophysical properties. Neuron. 8: 663-76. PMID 1314619 DOI: 10.1016/0896-6273(92)90088-U  1
1991 Stephan M, Agnew WS. Voltage-sensitive Na+ channels: motifs, modes and modulation. Current Opinion in Cell Biology. 3: 676-84. PMID 1722983 DOI: 10.1016/0955-0674(91)90041-V  1
1991 Zhou JY, Potts JF, Trimmer JS, Agnew WS, Sigworth FJ. Multiple gating modes and the effect of modulating factors on the microI sodium channel. Neuron. 7: 775-85. PMID 1660285 DOI: 10.1016/0896-6273(91)90280-D  1
1991 Ptacek LJ, Trimmer JS, Agnew WS, Roberts JW, Petajan JH, Leppert M. Paramyotonia congenita and hyperkalemic periodic paralysis map to the same sodium-channel gene locus. American Journal of Human Genetics. 49: 851-4. PMID 1654742  1
1991 Hingorani SR, Agnew WS. A rapid ion-exchange assay for detergent-solubilized inositol 1,4,5-trisphosphate receptors. Analytical Biochemistry. 194: 204-13. PMID 1651064 DOI: 10.1016/0003-2697(91)90169-T  1
1991 Ptacek LJ, Tyler F, Trimmer JS, Agnew WS, Leppert M. Analysis in a large hyperkalemic periodic paralysis pedigree supports tight linkage to a sodium channel locus. American Journal of Human Genetics. 49: 378-82. PMID 1651050  1
1991 Agnew WS, Cooper EC, Shenkel S, Correa AM, James WM, Ukomadu C, Tomiko SA. Voltage-sensitive sodium channels: agents that perturb inactivation gating. Annals of the New York Academy of Sciences. 625: 200-23. PMID 1647724 DOI: 10.1111/j.1749-6632.1991.tb33842.x  1
1990 Trimmer JS, Cooperman SS, Agnew WS, Mandel G. Regulation of muscle sodium channel transcripts during development and in response to denervation. Developmental Biology. 142: 360-7. PMID 2175278 DOI: 10.1016/0012-1606(90)90356-N  1
1990 Correa AM, Bezanilla F, Agnew WS. Voltage activation of purified eel sodium channels reconstituted into artificial liposomes. Biochemistry. 29: 6230-40. PMID 2169867  1
1989 Trimmer JS, Cooperman SS, Tomiko SA, Zhou JY, Crean SM, Boyle MB, Kallen RG, Sheng ZH, Barchi RL, Sigworth FJ. Primary structure and functional expression of a mammalian skeletal muscle sodium channel. Neuron. 3: 33-49. PMID 2559760 DOI: 10.1016/0896-6273(89)90113-X  1
1989 Emerick MC, Agnew WS. Identification of phosphorylation sites for adenosine 3',5'-cyclic phosphate dependent protein kinase on the voltage-sensitive sodium channel from Electrophorus electricus. Biochemistry. 28: 8367-80. PMID 2557902  1
1989 Cooper EC, Agnew WS. Reconstituted voltage-sensitive sodium channels from eel electroplax: activation of permeability by quaternary lidocaine, N-bromoacetamide, and N-bromosuccinimide. The Journal of Membrane Biology. 111: 253-64. PMID 2557451 DOI: 10.1007/BF01871010  1
1989 Shenkel S, Cooper EC, James W, Agnew WS, Sigworth FJ. Purified, modified eel sodium channels are active in planar bilayers in the absence of activating neurotoxins. Proceedings of the National Academy of Sciences of the United States of America. 86: 9592-6. PMID 2556720 DOI: 10.1073/pnas.86.23.9592  1
1989 James WM, Emerick MC, Agnew WS. Affinity purification of the voltage-sensitive sodium channel from electroplax with resins selective for sialic acid. Biochemistry. 28: 6001-9. PMID 2550067  1
1989 Agnew WS. Excitation-contraction coupling. Cloning of the SR foot. Nature. 339: 422-3. PMID 2542799 DOI: 10.1038/339422a0  1
1989 Trimmer JS, Agnew WS. Molecular diversity of voltage-sensitive Na channels. Annual Review of Physiology. 51: 401-18. PMID 2540698 DOI: 10.1146/annurev.ph.51.030189.002153  1
1989 James WM, Agnew WS. Alpha-(2----8)-polysialic acid immunoreactivity in voltage-sensitive sodium channel of eel electric organ. Proceedings of the Royal Society of London. Series B, Biological Sciences. 237: 233-45. PMID 2475874  1
1988 Correa AM, Agnew WS. Fusion of native or reconstituted membranes to liposomes, optimized for single channel recording. Biophysical Journal. 54: 569-75. PMID 2850031 DOI: 10.1016/S0006-3495(88)82991-6  1
1988 Agnew WS. Excitation-contraction coupling. Proteins that bridge the gap. Nature. 334: 299-300. PMID 2455870 DOI: 10.1038/334299a0  1
1988 Agnew WS. A Rosetta stone for K channels. Nature. 331: 114-5. PMID 2448634 DOI: 10.1038/331114a0  1
1988 Agnew WS, Cooper EC, James WM, Tomiko SA, Rosenberg RL, Emerick MC, Correa AM, Zhou JY. Chapter 17 Voltage-Sensitive Sodium Channels: Molecular Structure and Function Current Topics in Membranes and Transport. 33: 329-365. DOI: 10.1016/S0070-2161(08)60907-7  1
1988 Agnew WS, Claudio T, Sigworth FJ. Preface Current Topics in Membranes and Transport. 33: xiii-xvi. DOI: 10.1016/S0070-2161(08)60889-8  1
1987 Agnew WS. Dual roles for DHP receptors in excitation--contraction coupling? Nature. 328: 297. PMID 3037386 DOI: 10.1038/328297a0  1
1987 Dean GE, Nelson PJ, Agnew WS, Rudnick G. Hydrodynamic properties of the chromaffin granule hydrogen ion pumping adenosinetriphosphatase. Biochemistry. 26: 2301-5. PMID 2887199  1
1987 James WM, Agnew WS. Multiple oligosaccharide chains in the voltage-sensitive Na channel from electrophorus electricus: evidence for alpha-2,8-linked polysialic acid. Biochemical and Biophysical Research Communications. 148: 817-26. PMID 2446601 DOI: 10.1016/0006-291X(87)90949-1  1
1987 Cooper EC, Tomiko SA, Agnew WS. Reconstituted voltage-sensitive sodium channel from Electrophorus electricus: chemical modifications that alter regulation of ion permeability. Proceedings of the National Academy of Sciences of the United States of America. 84: 6282-6. PMID 2442755  1
1986 Agnew WS, Tomiko SA, Rosenberg RL, Emerick MC, Cooper EC. The structure and function of the voltage-sensitive Na channel. Annals of the New York Academy of Sciences. 479: 238-56. PMID 2433994  1
1986 Agnew WS. Neurochemistry. Lessons from large molecules. Nature. 322: 770-1. PMID 2427954 DOI: 10.1038/322770a0  1
1986 Tomiko SA, Rosenberg RL, Emerick MC, Agnew WS. Fluorescence assay for neurotoxin-modulated ion transport by the reconstituted voltage-activated sodium channel isolated from eel electric organ. Biochemistry. 25: 2162-74. PMID 2423121  0.8
1985 Agnew WS. Squalene synthetase. Methods in Enzymology. 110: 359-73. PMID 3894879  1
1984 Agnew WS. Voltage-regulated sodium channel molecules. Annual Review of Physiology. 46: 517-30. PMID 6324661 DOI: 10.1146/annurev.ph.46.030184.002505  1
1984 Rosenberg RL, Tomiko SA, Agnew WS. Reconstitution of neurotoxin-modulated ion transport by the voltage-regulated sodium channel isolated from the electroplax of Electrophorus electricus. Proceedings of the National Academy of Sciences of the United States of America. 81: 1239-43. PMID 6322191  1
1984 Rosenberg RL, Tomiko SA, Agnew WS. Single-channel properties of the reconstituted voltage-regulated Na channel isolated from the electroplax of Electrophorus electricus. Proceedings of the National Academy of Sciences of the United States of America. 81: 5594-8. PMID 6089214  1
1983 Agnew WS, Miller JA, Ellisman MH, Rosenberg RL, Tomiko SA, Levinson SR. The voltage-regulated sodium channel from the electroplax of Electrophorus electricus. Cold Spring Harbor Symposia On Quantitative Biology. 48: 165-79. PMID 6327150  1
1983 Ellisman MH, Miller JA, Agnew WS. Molecular morphology of the tetrodotoxin-binding sodium channel protein from Electrophorus electricus in solubilized and reconstituted preparations. The Journal of Cell Biology. 97: 1834-40. PMID 6315745  1
1983 Miller JA, Agnew WS, Levinson SR. Principal glycopeptide of the tetrodotoxin/saxitoxin binding protein from Electrophorus electricus: isolation and partial chemical and physical characterization. Biochemistry. 22: 462-70. PMID 6186277  1
1982 Moore AC, Agnew WS, Raftery MA. Biochemical characterization of the tetrodotoxin binding protein from Electrophorus electricus. Biochemistry. 21: 6212-20. PMID 6295460  1
1982 Ellisman MH, Agnew WS, Miller JA, Levinson SR. Electron microscopic visualization of the tetrodotoxin-binding protein from Electrophorus electricus. Proceedings of the National Academy of Sciences of the United States of America. 79: 4461-5. PMID 6289303  1
1980 Agnew WS, Moore AC, Levinson SR, Raftery MA. Identification of a large molecular weight peptide associated with a tetrodotoxin binding protein from the electroplax of Electrophorus electricus. Biochemical and Biophysical Research Communications. 92: 860-6. PMID 7362610 DOI: 10.1016/0006-291X(80)90782-2  1
1979 Agnew WS, Raftery MA. Solubilized tetrodotoxin binding component from the electroplax of Electrophorus electricus. Stability as a function of mixed lipid-detergent micelle composition. Biochemistry. 18: 1912-9. PMID 435456  1
1979 Popják G, Agnew WS. Squalene synthetase. Molecular and Cellular Biochemistry. 27: 97-116. PMID 41173 DOI: 10.1007/BF00218354  1
1978 Agnew WS, Popják G. Squalene synthetase. Solubilization from yeast microsomes of a phospholipid-requiring enzyme. The Journal of Biological Chemistry. 253: 4574-83. PMID 350878  1
1978 Agnew WS, Levinson SR, Brabson JS, Raftery MA. Purification of the tetrodotoxin-binding component associated with the voltage-sensitive sodium channel from Electrophorus electricus electroplax membranes. Proceedings of the National Academy of Sciences of the United States of America. 75: 2606-10. PMID 275831  1
1978 Agnew WS, Popják G. Squalene synthetase. Stoichiometry and kinetics of presqualene pyrophosphate and squalene synthesis by yeast microsomes. The Journal of Biological Chemistry. 253: 4566-73. PMID 26684  1
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