Shin Numao, Ph.D. - Publications

2003 University of British Columbia, Vancouver, Vancouver, BC, Canada 
enzyme mechanisms, protein structure/function relationships, enzyme inhibitor design/synthesis and protein engineering

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Butendeich H, Pierret NM, Numao S. Evaluation of a liquid dispenser for assay development and enzymology in 1536-well format. Journal of Laboratory Automation. 18: 245-50. PMID 23355542 DOI: 10.1177/2211068212472184  0.52
2011 Lizak C, Gerber S, Numao S, Aebi M, Locher KP. X-ray structure of a bacterial oligosaccharyltransferase. Nature. 474: 350-5. PMID 21677752 DOI: 10.1038/nature10151  0.52
2010 Schwarz F, Huang W, Li C, Schulz BL, Lizak C, Palumbo A, Numao S, Neri D, Aebi M, Wang LX. A combined method for producing homogeneous glycoproteins with eukaryotic N-glycosylation. Nature Chemical Biology. 6: 264-6. PMID 20190762 DOI: 10.1038/nchembio.314  0.52
2009 Slynko V, Schubert M, Numao S, Kowarik M, Aebi M, Allain FH. NMR structure determination of a segmentally labeled glycoprotein using in vitro glycosylation. Journal of the American Chemical Society. 131: 1274-81. PMID 19154179 DOI: 10.1021/ja808682v  0.52
2006 Kowarik M, Numao S, Feldman MF, Schulz BL, Callewaert N, Kiermaier E, Catrein I, Aebi M. N-linked glycosylation of folded proteins by the bacterial oligosaccharyltransferase. Science (New York, N.Y.). 314: 1148-50. PMID 17110579 DOI: 10.1126/science.1134351  0.52
2006 Kowarik M, Young NM, Numao S, Schulz BL, Hug I, Callewaert N, Mills DC, Watson DC, Hernandez M, Kelly JF, Wacker M, Aebi M. Definition of the bacterial N-glycosylation site consensus sequence. The Embo Journal. 25: 1957-66. PMID 16619027 DOI: 10.1038/sj.emboj.7601087  0.52
2005 Glover KJ, Weerapana E, Numao S, Imperiali B. Chemoenzymatic synthesis of glycopeptides with PglB, a bacterial oligosaccharyl transferase from Campylobacter jejuni. Chemistry & Biology. 12: 1311-5. PMID 16356848 DOI: 10.1016/j.chembiol.2005.10.004  0.52
2005 Li C, Begum A, Numao S, Park KH, Withers SG, Brayer GD. Acarbose rearrangement mechanism implied by the kinetic and structural analysis of human pancreatic alpha-amylase in complex with analogues and their elongated counterparts. Biochemistry. 44: 3347-57. PMID 15736945 DOI: 10.1021/bi048334e  0.52
2005 Maurus R, Begum A, Kuo HH, Racaza A, Numao S, Andersen C, Tams JW, Vind J, Overall CM, Withers SG, Brayer GD. Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase. Protein Science : a Publication of the Protein Society. 14: 743-55. PMID 15722449 DOI: 10.1110/ps.041079305  0.52
2004 Numao S, Damager I, Li C, Wrodnigg TM, Begum A, Overall CM, Brayer GD, Withers SG. In situ extension as an approach for identifying novel alpha-amylase inhibitors. The Journal of Biological Chemistry. 279: 48282-91. PMID 15304511 DOI: 10.1074/jbc.M406804200  0.52
2004 Damager I, Numao S, Chen H, Brayer GD, Withers SG. Synthesis and characterisation of novel chromogenic substrates for human pancreatic alpha-amylase. Carbohydrate Research. 339: 1727-37. PMID 15220082 DOI: 10.1016/j.carres.2004.05.019  0.52
2003 Numao S, Kuntz DA, Withers SG, Rose DR. Insights into the mechanism of Drosophila melanogaster Golgi alpha-mannosidase II through the structural analysis of covalent reaction intermediates. The Journal of Biological Chemistry. 278: 48074-83. PMID 12960159 DOI: 10.1074/jbc.M309249200  0.52
2002 Numao S, Maurus R, Sidhu G, Wang Y, Overall CM, Brayer GD, Withers SG. Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase. Biochemistry. 41: 215-25. PMID 11772019 DOI: 10.1021/bi0115636  0.52
2001 Douglas DJ, Collings BA, Numao S, Nesatyy VJ. Validation of liquid-liquid extraction followed by flow-injection negative ion electrospray mass spectrometry assay to Topiramate in human plasma Rapid Communications in Mass Spectrometry. 15: 159-163. PMID 11180545 DOI: 10.1002/1097-0231(20010130)15:2<159::AID-RCM210>3.0.CO;2-W  0.52
2000 Numao S, He S, Evjen G, Howard S, Tollersrud OK, Withers SG. Identification of Asp197 as the catalytic nucleophile in the family 38 alpha-mannosidase from bovine kidney lysosomes. Febs Letters. 484: 175-8. PMID 11078873 DOI: 10.1016/S0014-5793(00)02148-7  0.52
1999 Rydberg EH, Sidhu G, Vo HC, Hewitt J, Côte HC, Wang Y, Numao S, MacGillivray RT, Overall CM, Brayer GD, Withers SG. Cloning, mutagenesis, and structural analysis of human pancreatic alpha-amylase expressed in Pichia pastoris. Protein Science : a Publication of the Protein Society. 8: 635-43. PMID 10091666 DOI: 10.1110/ps.8.3.635  0.52
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