Youngjoo Kwon, Ph.D. - Publications

Affiliations: 
2002 University of Houston, Houston, TX, United States 
Area:
Biological NMR of Nucleic Acids and Proteins; Microarray BIOCHIP Technologies

159 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hwang SY, Park S, Kwon Y. Recent therapeutic trends and promising targets in triple negative breast cancer. Pharmacology & Therapeutics. PMID 30825473 DOI: 10.1016/j.pharmthera.2019.02.006  0.44
2018 Cho H, Hee Seo S, Na Y, Kwon Y. The synthesis and anticancer activities of chiral epoxy-substituted chromone analogs. Bioorganic Chemistry. 84: 347-354. PMID 30530076 DOI: 10.1016/j.bioorg.2018.11.054  0.44
2018 Shrestha A, Park S, Jang HJ, Katila P, Shrestha R, Kwon Y, Lee ES. A new phenolic series of indenopyridinone as topoisomerase inhibitors: Design, synthesis, and structure-activity relationships. Bioorganic & Medicinal Chemistry. PMID 30262132 DOI: 10.1016/j.bmc.2018.09.021  0.44
2018 Arepalli SK, Lee C, Sim S, Lee K, Jo H, Jun KY, Kwon Y, Kang JS, Jung JK, Lee H. Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors. Bioorganic & Medicinal Chemistry. PMID 30253887 DOI: 10.1016/j.bmc.2018.09.019  0.92
2018 Shrestha A, Park S, Shin S, Man Kadayat T, Bist G, Katila P, Kwon Y, Lee ES. Design, synthesis, biological evaluation, structure-activity relationship study, and mode of action of 2-phenol-4,6-dichlorophenyl-pyridines. Bioorganic Chemistry. 79: 1-18. PMID 29715635 DOI: 10.1016/j.bioorg.2018.03.033  0.44
2018 Bae HD, Lee J, Jun KY, Kwon Y, Lee K. Modification of translationally controlled tumor protein-derived protein transduction domain for improved intranasal delivery of insulin. Drug Delivery. 25: 1025-1032. PMID 29688087 DOI: 10.1080/10717544.2018.1464081  0.92
2018 Kim J, Kim H, Roh H, Kwon Y. Causes of hyperhomocysteinemia and its pathological significance. Archives of Pharmacal Research. PMID 29552692 DOI: 10.1007/s12272-018-1016-4  0.56
2018 Magar TBT, Seo SH, Kadayat TM, Jo H, Shrestha A, Bist G, Katila P, Kwon Y, Lee ES. Synthesis and SAR study of new hydroxy and chloro-substituted 2,4-diphenyl 5H-chromeno[4,3-b]pyridines as selective topoisomerase IIα-targeting anticancer agents. Bioorganic & Medicinal Chemistry. PMID 29510948 DOI: 10.1016/j.bmc.2018.02.035  0.44
2018 Jeon KH, Yu HV, Kwon Y. Hyperactivated m-calpain affects acquisition of doxorubicin resistance in breast cancer cells. Biochimica Et Biophysica Acta. PMID 29425806 DOI: 10.1016/j.bbagen.2018.02.002  0.44
2018 Shrestha A, Jo H, Kwon Y, Lee ES. Design, synthesis, and structure-activity relationships of new benzofuro[3,2-b]pyridin-7-ols as DNA topoisomerase II inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 29402741 DOI: 10.1016/j.bmcl.2018.01.048  0.44
2018 Khadka DB, Park S, Jin Y, Han J, Kwon Y, Cho WJ. Design, synthesis, and biological evaluation of 1,3-diarylisoquinolines as novel topoisomerase I catalytic inhibitors. European Journal of Medicinal Chemistry. 143: 200-215. PMID 29174815 DOI: 10.1016/j.ejmech.2017.11.011  0.44
2017 Choi B, Choi SK, Park YN, Kwak SY, Lee HJ, Kwon Y, Na Y, Lee YS. Sensitization of lung cancer cells by altered dimerization of HSP27. Oncotarget. 8: 105372-105382. PMID 29285257 DOI: 10.18632/oncotarget.22192  0.44
2017 Chae SW, Lee J, Park JH, Kwon Y, Na Y, Lee HJ. Intestinal P-glycoprotein inhibitors, benzoxanthone analogues. The Journal of Pharmacy and Pharmacology. PMID 29238994 DOI: 10.1111/jphp.12832  0.44
2017 Nam HY, Na EJ, Lee E, Kwon Y, Kim HJ. Antiepileptic and Neuroprotective Effects of Oleamide in Rat Striatum on Kainate-Induced Behavioral Seizure and Excitotoxic Damage via Calpain Inhibition. Frontiers in Pharmacology. 8: 817. PMID 29209207 DOI: 10.3389/fphar.2017.00817  0.44
2017 Arepalli SK, Park B, Lee K, Jo H, Jun KY, Kwon Y, Kang JS, Jung JK, Lee H. Design, synthesis and biological evaluation of 1,3-diphenylbenzo[f][1,7]naphthyrdines. Bioorganic & Medicinal Chemistry. PMID 28870801 DOI: 10.1016/j.bmc.2017.08.030  0.92
2017 Hwang SY, Kwak SY, Kwon Y, Lee YS, Na Y. Synthesis and biological effect of chrom-4-one derivatives as functional inhibitors of heat shock protein 27. European Journal of Medicinal Chemistry. 139: 892-900. PMID 28869891 DOI: 10.1016/j.ejmech.2017.08.065  0.44
2017 Choi SK, Mun GI, Choi E, Kim SY, Kwon Y, Na Y, Lee YS. The Conjugated Double Bond of Coniferyl Aldehyde Is Essential for Heat Shock Factor 1 Mediated Cytotoprotection. Journal of Natural Products. PMID 28737916 DOI: 10.1021/acs.jnatprod.7b00126  0.44
2017 Thapa Magar TB, Kadayat TM, Lee HJ, Park S, Bist G, Shrestha A, Kwon Y, Lee ES. 2-Chlorophenyl-substituted benzofuro[3,2-b]pyridines with enhanced topoisomerase inhibitory activity: The role of the chlorine substituent. Bioorganic & Medicinal Chemistry Letters. PMID 28633898 DOI: 10.1016/j.bmcl.2017.06.025  0.44
2017 Bist G, Park S, Song C, Thapa Magar TB, Shrestha A, Kwon Y, Lee ES. Dihydroxylated 2,6-diphenyl-4-chlorophenylpyridines: Topoisomerase I and IIα dual inhibitors with DNA non-intercalative catalytic activity. European Journal of Medicinal Chemistry. 133: 69-84. PMID 28384547 DOI: 10.1016/j.ejmech.2017.03.048  0.44
2017 Park S, Thapa Magar TB, Kadayat TM, Lee HJ, Bist G, Shrestha A, Lee ES, Kwon Y. Rational design, synthesis, and evaluation of novel 2,4-Chloro- and Hydroxy-Substituted diphenyl Benzofuro[3,2-b]Pyridines: Non-intercalative catalytic topoisomerase I and II dual inhibitor. European Journal of Medicinal Chemistry. 127: 318-333. PMID 28068603 DOI: 10.1016/j.ejmech.2017.01.003  0.44
2016 Jeon KH, Yu HB, Kwak SY, Kwon Y, Na Y. Synthesis and topoisomerases inhibitory activity of heteroaromatic chalcones. Bioorganic & Medicinal Chemistry. PMID 27707625 DOI: 10.1016/j.bmc.2016.09.051  0.44
2016 Islam MS, Park S, Song C, Kadi AA, Kwon Y, Rahman AF. Fluorescein hydrazones: A series of novel non-intercalative topoisomerase IIα catalytic inhibitors induce G1 arrest and apoptosis in breast and colon cancer cells. European Journal of Medicinal Chemistry. 125: 49-67. PMID 27654394 DOI: 10.1016/j.ejmech.2016.09.004  0.92
2016 Park S, Kadayat TM, Jun KY, Thapa Magar TB, Bist G, Shrestha A, Lee ES, Kwon Y. Novel 2-aryl-4-(4'-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors. European Journal of Medicinal Chemistry. 125: 14-28. PMID 27643560 DOI: 10.1016/j.ejmech.2016.09.019  0.92
2016 Jun KY, Kwon Y. Proposal of Dual Inhibitor Targeting ATPase Domains of Topoisomerase II and Heat Shock Protein 90. Biomolecules & Therapeutics. 24: 453-68. PMID 27582553 DOI: 10.4062/biomolther.2016.168  0.92
2016 Park S, Hong E, Kwak SY, Jun KY, Lee ES, Kwon Y, Na Y. Synthesis and biological evaluation of C1-O-substituted-3-(3-butylamino-2-hydroxy-propoxy)-xanthen-9-one as topoisomerase IIα catalytic inhibitors. European Journal of Medicinal Chemistry. 123: 211-225. PMID 27484510 DOI: 10.1016/j.ejmech.2016.07.046  0.92
2016 Kim JH, Jung YJ, Choi B, Lee NL, Lee HJ, Kwak SY, Kwon Y, Na Y, Lee YS. Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules. Oncotarget. PMID 27449291 DOI: 10.18632/oncotarget.10629  0.44
2016 Jeon KH, Lee E, Jun KY, Eom JE, Kwak SY, Na Y, Kwon Y. Neuroprotective effect of synthetic chalcone derivatives as competitive dual inhibitors against μ-calpain and cathepsin B through the downregulation of tau phosphorylation and insoluble Aβ peptide formation. European Journal of Medicinal Chemistry. 121: 433-444. PMID 27318120 DOI: 10.1016/j.ejmech.2016.06.008  0.92
2016 Thapa P, Kadayat TM, Park S, Shin S, Thapa Magar TB, Bist G, Shrestha A, Na Y, Kwon Y, Lee ES. Synthesis and biological evaluation of 2-phenol-4-chlorophenyl-6-aryl pyridines as topoisomerase II inhibitors and cytotoxic agents. Bioorganic Chemistry. 66: 145-159. PMID 27174797 DOI: 10.1016/j.bioorg.2016.04.007  0.92
2016 Baek KH, Yu HV, Kim E, Na Y, Kwon Y. Calcium influx-mediated translocation of m-calpain induces Ku80 cleavage and enhances the Ku80-related DNA repair pathway. Oncotarget. PMID 27121057 DOI: 10.18632/oncotarget.8791  0.92
2016 Ahmad P, Woo H, Jun KY, Kadi AA, Abdel-Aziz HA, Kwon Y, Rahman AF. Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure-activity relationship study of pyrazoline derivatives: An ATP-competitive human topoisomerase IIα catalytic inhibitor. Bioorganic & Medicinal Chemistry. PMID 26988802 DOI: 10.1016/j.bmc.2016.03.017  0.92
2016 Karki R, Jun KY, Kadayat TM, Shin S, Thapa Magar TB, Bist G, Shrestha A, Na Y, Kwon Y, Lee ES. A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study. European Journal of Medicinal Chemistry. 113: 228-245. PMID 26945111 DOI: 10.1016/j.ejmech.2016.02.050  0.92
2016 Kadayat TM, Park S, Jun KY, Magar TB, Bist G, Shrestha A, Na Y, Kwon Y, Lee ES. Effect of chlorine substituent on cytotoxic activities: Design and synthesis of systematically modified 2,4-diphenyl-5H-indeno[1,2-b]pyridines. Bioorganic & Medicinal Chemistry Letters. PMID 26927425 DOI: 10.1016/j.bmcl.2016.02.053  0.92
2016 Lee E, Kwon YU. Multi-component electrocatalyst for low-temperature fuel cells synthesized via sonochemical reactions. Ultrasonics Sonochemistry. 29: 401-12. PMID 26585021 DOI: 10.1016/j.ultsonch.2015.10.013  0.44
2015 Chang YY, Wang MZ, Abdesselam A, Adachi I, Adamczyk K, Aihara H, Al Said S, Asner DM, Atmacan H, Aushev T, Babu V, Badhrees I, Bakich AM, Barberio E, Bhuyan B, ... ... Kwon YJ, et al. Observation of B^{0}→pΛ[over ¯]D^{(*)-}. Physical Review Letters. 115: 221803. PMID 26650291 DOI: 10.1103/PhysRevLett.115.221803  0.56
2015 Noh JW, Kim J, Park J, Kim HJ, Kwon YD. Gender Difference in Relationship between Health-Related Quality of Life and Work Status. Plos One. 10: e0143579. PMID 26629811 DOI: 10.1371/journal.pone.0143579  0.56
2015 Kim JH, Joung EJ, Lee SJ, Kwack JY, Kwon YS. Intraoperative bleeding control during cesarean delivery of complete placenta previa with transient occlusion of uterine arteries. Obstetrics & Gynecology Science. 58: 522-524. PMID 26623419 DOI: 10.5468/ogs.2015.58.6.522  0.36
2015 Yu J, Kwon YS, Kim S, Han CS, Farber N, Kim J, Byun SS, Kim WJ, Jeon SS, Kim IY. Pathological Outcome Following Radical Prostatectomy in Men with PSA Greater than 10 and Histologically Favorable-Risk Prostate Cancer. The Journal of Urology. PMID 26608903 DOI: 10.1016/j.juro.2015.11.031  0.56
2015 Kang DH, Park JW, Jeon EY, Kim SE, Kim JH, Kwon YS, Park SA, Park CK. Successful Treatment of Bleeding Duodenal Varix by Percutaneous Transsplenic Embolization. The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi. 66: 286-90. PMID 26586353 DOI: 10.4166/kjg.2015.66.5.286  0.36
2015 Park SE, Kim OH, Kwak JH, Lee KH, Kwon YI, Chung KH, Lee JH. Antihyperglycemic effect of short-term arginyl-fructose supplementation in subjects with prediabetes and newly diagnosed type 2 diabetes: randomized, double-blinded, placebo-controlled trial. Trials. 16: 521. PMID 26578409 DOI: 10.1186/s13063-015-1036-z  0.56
2015 Min B, Park H, Lee S, Li Y, Choi JM, Lee JY, Kim J, Choi YD, Kwon YG, Lee HW, Bae SC, Yun CO, Chung KC. CHIP-mediated degradation of transglutaminase 2 negatively regulates tumor growth and angiogenesis in renal cancer. Oncogene. PMID 26568304 DOI: 10.1038/onc.2015.439  0.56
2015 Park H, Lee S, Shrestha P, Kim J, Park JA, Ko Y, Ban YH, Park DY, Ha SJ, Koh GY, Hong VS, Mochizuki N, Kim YM, Lee W, Kwon YG. AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation. The Journal of Cell Biology. 211: 619-37. PMID 26553931 DOI: 10.1083/jcb.201503113  0.56
2015 Yoo MY, Lee ES, Kim SK, Park SY, Kwon Y, Yun T, Kim TS. Multicentric Primary Angiosarcoma of Bone Mimicking Metastasis on (18)F-FDG PET/CT in a Patient with a History of Sigmoid Colon Cancer: a Case Report. Nuclear Medicine and Molecular Imaging. 49: 321-4. PMID 26550053 DOI: 10.1007/s13139-015-0353-1  0.44
2015 Rhee CK, Chang JH, Choi EG, Kim HK, Kwon YS, Kyung SY, Lee JH, Park MJ, Yoo KH, Oh YM. Zabofloxacin versus moxifloxacin in patients with COPD exacerbation: a multicenter, double-blind, double-dummy, randomized, controlled, Phase III, non-inferiority trial. International Journal of Chronic Obstructive Pulmonary Disease. 10: 2265-75. PMID 26543359 DOI: 10.2147/COPD.S90948  0.56
2015 Jeong DK, Lee HW, Kwon YM. Clinical Value of Procalcitonin in Patients with Spinal Infection. Journal of Korean Neurosurgical Society. 58: 271-5. PMID 26539272 DOI: 10.3340/jkns.2015.58.3.271  0.4
2015 Kwon YK, Kim J, Cho KH. Dynamical Robustness Against Multiple Mutations in Signaling Networks. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. PMID 26529781 DOI: 10.1109/TCBB.2015.2495251  0.56
2015 Kwon YJ, Kwon TW, Um EH, Shin S, Cho YP, Kim JM, Lee SH, Hwang SJ. Anatomical Popliteal Artery Entrapment Syndrome Caused by an Aberrant Plantaris Muscle. Vascular Specialist International. 31: 95-101. PMID 26509140 DOI: 10.5758/vsi.2015.31.3.95  0.44
2015 Lee KH, Moon SY, Kim IA, Kwon SY, Kim JH, Choe WH, Kwon YW. [A Case of Delayed-onset Multiple Metastatic Infection following Liver Abscess]. The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi. 66: 237-41. PMID 26493511 DOI: 10.4166/kjg.2015.66.4.237  0.36
2015 Lee S, Davis R, Judge LW, Kwon YH, Han K, Kim J, Kim J, Kim J. Gender-Based Correlation Profiles Among the Release Factors and Distance Thrown in Paralympic Seated Shot Put. Adapted Physical Activity Quarterly : Apaq. 32: 318-30. PMID 26485736 DOI: 10.1123/APAQ.2014-0148  0.56
2015 Kim KH, Lee YT, Hwang HS, Kwon YM, Jung YJ, Lee Y, Lee JS, Lee YN, Park S, Kang SM. Alum Adjuvant Enhances Protection against Respiratory Syncytial Virus but Exacerbates Pulmonary Inflammation by Modulating Multiple Innate and Adaptive Immune Cells. Plos One. 10: e0139916. PMID 26468884 DOI: 10.1371/journal.pone.0139916  0.44
2015 Byun S, Shin SH, Lee E, Lee J, Lee SY, Farrand L, Jung SK, Cho YY, Um SJ, Sin HS, Kwon YJ, Zhang C, Tsang BK, Bode AM, Lee HJ, et al. The retinoic acid derivative, ABPN, inhibits pancreatic cancer through induction of Nrdp1. Carcinogenesis. PMID 26464195 DOI: 10.1093/carcin/bgv148  0.44
2015 Kwon YS, Lee DY, Rakwal R, Baek SB, Lee JH, Kwak YS, Seo JS, Chung WS, Bae DW, Kim SG. Proteomic analyses of the interaction between the plant-growth promoting rhizobacterium Paenibacillus polymyxa E681 and Arabidopsis thaliana. Proteomics. PMID 26460066 DOI: 10.1002/pmic.201500196  0.56
2015 Song WJ, Sintobin I, Sohn KH, Kang MG, Park HK, Jo EJ, Lee SE, Yang MS, Kim SH, Park HK, Kwon YE, Kim TB, Kim SH, Park HW, Chang YS, et al. Staphylococcal enterotoxin IgE sensitization in late-onset severe eosinophilic asthma in the elderly. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. PMID 26436720 DOI: 10.1111/cea.12652  0.56
2015 Lee JH, Jiang Y, Kwon YT, Lee MJ. Pharmacological Modulation of the N-End Rule Pathway and its Therapeutic Implications. Trends in Pharmacological Sciences. PMID 26434644 DOI: 10.1016/j.tips.2015.07.004  0.56
2015 Abdesselam A, Adachi I, Adametz A, Adye T, Ahmed H, Aihara H, Akar S, Alam MS, Albert J, Al Said S, Andreassen R, Angelini C, Anulli F, Arinstein K, Arnaud N, ... ... Kwon YJ, et al. First Observation of CP Violation in B[over ¯]^{0}→D_{CP}^{(*)}h^{0} Decays by a Combined Time-Dependent Analysis of BABAR and Belle Data. Physical Review Letters. 115: 121604. PMID 26430984 DOI: 10.1103/PhysRevLett.115.121604  0.36
2015 Kwon Y, Pahk K, Park S, Rosenthal RJ. Metabolic Surgery Could Restore Hepatic Glucose Metabolism: Results from F-18 Fluorodeoxyglucose Positron Emission Tomography. Obesity Surgery. PMID 26420764 DOI: 10.1007/s11695-015-1895-0  0.44
2015 Kim JS, Jung GI, Choi JH, Lee TH, Kim AH, Oh HB, Kwon Y, Lee ES, Cho YB, Jun JH. Development of multi-colored LED system for therapeutic application. Technology and Health Care : Official Journal of the European Society For Engineering and Medicine. 23: S511-S517. PMID 26410518 DOI: 10.3233/THC-150988  0.44
2015 Min SK, Park JS, Luo L, Kwon YS, Lee HC, Jung Shim H, Kim ID, Lee JK, Shin HS. Assessment of C-phycocyanin effect on astrocytes-mediated neuroprotection against oxidative brain injury using 2D and 3D astrocyte tissue model. Scientific Reports. 5: 14418. PMID 26399322 DOI: 10.1038/srep14418  0.24
2015 Kwon Y, Song J, Lee H, Kim EY, Lee K, Lee SK, Kim S. Design, Synthesis, and Biological Activity of Sulfonamide Analogues of Antofine and Cryptopleurine as Potent and Orally Active Antitumor Agents. Journal of Medicinal Chemistry. PMID 26393416 DOI: 10.1021/acs.jmedchem.5b00764  0.56
2015 Kim BR, Seo SH, Park MS, Lee SH, Kwon Y, Rho SB. sMEK1 inhibits endothelial cell proliferation by attenuating VEGFR-2-dependent-Akt/eNOS/HIF-1α signaling pathways. Oncotarget. PMID 26378810 DOI: 10.18632/oncotarget.5570  0.92
2015 Park S, Kim B, Kwon Y. Anisotropic superfluidity of (4)He on a C36 fullerene molecule. The Journal of Chemical Physics. 143: 104311. PMID 26374039 DOI: 10.1063/1.4930857  0.44
2015 Park IH, Kong SY, Ro JY, Kwon Y, Kang JH, Mo HJ, Jung SY, Lee S, Lee KS, Kang HS, Lee E, Joo J, Ro J. Prognostic Implications of Tumor-Infiltrating Lymphocytes in Association With Programmed Death Ligand 1 Expression in Early-Stage Breast Cancer. Clinical Breast Cancer. PMID 26364145 DOI: 10.1016/j.clbc.2015.07.006  0.44
2015 Thapa P, Jun KY, Kadayat TM, Park C, Zheng Z, Thapa Magar TB, Bist G, Shrestha A, Na Y, Kwon Y, Lee ES. Design and synthesis of conformationally constrained hydroxylated 4-phenyl-2-aryl chromenopyridines as novel and selective topoisomerase II-targeted antiproliferative agents. Bioorganic & Medicinal Chemistry. PMID 26361737 DOI: 10.1016/j.bmc.2015.08.018  0.92
2015 Kwon YS, Kim JH, Jang JS, Kim CH, Kwon KJ, Yon JH. Analysis of radiofrequency lesions in egg whites in vitro produced by application of the Tew electrode for different temperatures and times. Pain Research & Management : the Journal of the Canadian Pain Society = Journal De La Societe Canadienne Pour Le Traitement De La Douleur. PMID 26357684  0.36
2015 Kwon Y, Kim KI, Tompkin J, Kim JH, Theobalt C. Efficient Learning of Image Super-Resolution and Compression Artifact Removal with Semi-Local Gaussian Processes. Ieee Transactions On Pattern Analysis and Machine Intelligence. 37: 1792-805. PMID 26353127 DOI: 10.1109/TPAMI.2015.2389797  0.36
2015 Heo Y, Pyo MJ, Bae SK, Lee H, Kwon YC, Kim JH, Kim B, Kim CG, Kang C, Kim E. Evaluation of Phototoxic and Skin Sensitization Potentials of PLA 2 -Free Bee Venom. Evidence-Based Complementary and Alternative Medicine : Ecam. 2015: 157367. PMID 26347784 DOI: 10.1155/2015/157367  0.56
2015 Khadka DB, Tran GH, Shin S, Nguyen HT, Cao HT, Zhao C, Jin Y, Van HT, Chau MV, Kwon Y, Le TN, Cho WJ. Substituted 2-arylquinazolinones: Design, synthesis, and evaluation of cytotoxicity and inhibition of topoisomerases. European Journal of Medicinal Chemistry. 103: 69-79. PMID 26334499 DOI: 10.1016/j.ejmech.2015.08.040  0.92
2015 Kadayat TM, Song C, Kwon Y, Lee ES. Modified 2,4-diaryl-5H-indeno[1,2-b]pyridines with hydroxyl and chlorine moiety: Synthesis, anticancer activity, and structure-activity relationship study. Bioorganic Chemistry. 62: 30-40. PMID 26218799 DOI: 10.1016/j.bioorg.2015.07.002  0.44
2015 Kadayat TM, Song C, Shin S, Magar TB, Bist G, Shrestha A, Thapa P, Na Y, Kwon Y, Lee ES. Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines. Bioorganic & Medicinal Chemistry. 23: 3499-512. PMID 26022080 DOI: 10.1016/j.bmc.2015.04.031  0.92
2015 Karki R, Song C, Kadayat TM, Magar TB, Bist G, Shrestha A, Na Y, Kwon Y, Lee ES. Topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of dihydroxylated 2,6-diphenyl-4-aryl pyridines. Bioorganic & Medicinal Chemistry. 23: 3638-54. PMID 25936262 DOI: 10.1016/j.bmc.2015.04.002  0.92
2015 Jun KY, Park SE, Liang JL, Jahng Y, Kwon Y. Benzo[b]tryptanthrin inhibits MDR1, topoisomerase activity, and reverses adriamycin resistance in breast cancer cells. Chemmedchem. 10: 827-35. PMID 25809558 DOI: 10.1002/cmdc.201500068  0.92
2015 Chae SW, Woo S, Park JH, Kwon Y, Na Y, Lee HJ. Xanthone analogues as potent modulators of intestinal P-glycoprotein. European Journal of Medicinal Chemistry. 93: 237-45. PMID 25686592 DOI: 10.1016/j.ejmech.2015.01.006  0.92
2015 Khadka DB, Woo H, Yang SH, Zhao C, Jin Y, Le TN, Kwon Y, Cho WJ. Modification of 3-arylisoquinolines into 3,4-diarylisoquinolines and assessment of their cytotoxicity and topoisomerase inhibition. European Journal of Medicinal Chemistry. 92: 583-607. PMID 25613224 DOI: 10.1016/j.ejmech.2015.01.016  0.92
2015 Kwon HB, Park C, Jeon KH, Lee E, Park SE, Jun KY, Kadayat TM, Thapa P, Karki R, Na Y, Park MS, Rho SB, Lee ES, Kwon Y. A series of novel terpyridine-skeleton molecule derivants inhibit tumor growth and metastasis by targeting topoisomerases. Journal of Medicinal Chemistry. 58: 1100-22. PMID 25603122 DOI: 10.1021/jm501023q  0.92
2015 Al-Sanea MM, Elkamhawy A, Zakaria A, Park BS, Kwon Y, Lee SH, Lee SW, Kim IT. Synthesis and in vitro screening of phenylbipyridinylpyrazole derivatives as potential antiproliferative agents. Molecules (Basel, Switzerland). 20: 1031-45. PMID 25584833 DOI: 10.3390/molecules20011031  0.92
2015 Kadayat TM, Park C, Jun KY, Magar TB, Bist G, Yoo HY, Kwon Y, Lee ES. Design and synthesis of novel 2,4-diaryl-5H-indeno[1,2-b]pyridine derivatives, and their evaluation of topoisomerase inhibitory activity and cytotoxicity. Bioorganic & Medicinal Chemistry. 23: 160-73. PMID 25481396 DOI: 10.1016/j.bmc.2014.11.010  0.92
2015 Karki R, Park C, Jun KY, Kadayat TM, Lee ES, Kwon Y. Synthesis and biological activity of 2,4-di-p-phenolyl-6-2-furanyl-pyridine as a potent topoisomerase II poison. European Journal of Medicinal Chemistry. 90: 360-78. PMID 25437622 DOI: 10.1016/j.ejmech.2014.11.045  0.92
2015 Kadayat TM, Park C, Jun KY, Thapa Magar TB, Bist G, Yoo HY, Kwon Y, Lee ES. Hydroxylated 2,4-diphenyl indenopyridine derivatives as a selective non-intercalative topoisomerase IIα catalytic inhibitor. European Journal of Medicinal Chemistry. 90: 302-14. PMID 25437617 DOI: 10.1016/j.ejmech.2014.11.046  0.92
2015 Kadayat TM, Song C, Kwon Y, Lee ES. Modified 2,4-diaryl-5H-indeno[1,2-b]pyridines with hydroxyl and chlorine moiety: Synthesis, anticancer activity, and structure-activity relationship study Bioorganic Chemistry. 62: 30-40. DOI: 10.1016/j.bioorg.2015.07.002  0.92
2014 Sethi G, Kwon Y, Burkhalter RJ, Pathak HB, Madan R, McHugh S, Atay S, Murthy S, Tawfik OW, Godwin AK. PTN signaling: Components and mechanistic insights in human ovarian cancer. Molecular Carcinogenesis. PMID 25418856 DOI: 10.1002/mc.22249  0.92
2014 Rahman AF, Park SE, Kadi AA, Kwon Y. Fluorescein hydrazones as novel nonintercalative topoisomerase catalytic inhibitors with low DNA toxicity. Journal of Medicinal Chemistry. 57: 9139-51. PMID 25333701 DOI: 10.1021/jm501263m  0.92
2014 Eom JE, Lee E, Jeon KH, Sim J, Suh M, Jhon GJ, Kwon Y. Development of an albumin copper binding (ACuB) assay to detect ischemia modified albumin. Analytical Sciences : the International Journal of the Japan Society For Analytical Chemistry. 30: 985-90. PMID 25312629 DOI: DN/JST.JSTAGE/analsci/30.985  0.92
2014 Jin CH, Jun KY, Lee E, Kim S, Kwon Y, Kim K, Na Y. Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. Bioorganic & Medicinal Chemistry. 22: 4553-65. PMID 25131958 DOI: 10.1016/j.bmc.2014.07.037  0.92
2014 Reddy VS, Hemadri V, Pasupuleti P, Perugu B, Lee EE, Eoma JE, Jeon KH, Kwon Y. Cobalt-albumin binding (CAB) assay: An advantageous and flaw free testing of albumin-cobalt binding Journal of Pharmaceutical and Biomedical Analysis. 99: 79-82. PMID 25086492 DOI: 10.1016/j.jpba.2014.06.016  0.92
2014 Karki R, Park C, Jun KY, Jee JG, Lee JH, Thapa P, Kadayat TM, Kwon Y, Lee ES. Synthesis, antitumor activity, and structure-activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitors. European Journal of Medicinal Chemistry. 84: 555-65. PMID 25062006 DOI: 10.1016/j.ejmech.2014.07.058  0.92
2014 My Van HT, Woo H, Jeong HM, Khadka DB, Yang SH, Zhao C, Jin Y, Lee ES, Youl Lee K, Kwon Y, Cho WJ. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors. European Journal of Medicinal Chemistry. 82: 181-94. PMID 24904965 DOI: 10.1016/j.ejmech.2014.05.047  0.92
2014 Jun KY, Kwon H, Park SE, Lee E, Karki R, Thapa P, Lee JH, Lee ES, Kwon Y. Discovery of dihydroxylated 2,4-diphenyl-6-thiophen-2-yl-pyridine as a non-intercalative DNA-binding topoisomerase II-specific catalytic inhibitor. European Journal of Medicinal Chemistry. 80: 428-38. PMID 24796883 DOI: 10.1016/j.ejmech.2014.04.066  0.92
2014 Lee E, Eom JE, Jeon KH, Kim TH, Kim E, Jhon GJ, Kwon Y. Evaluation of albumin structural modifications through cobalt-albumin binding (CAB) assay. Journal of Pharmaceutical and Biomedical Analysis. 91: 17-23. PMID 24434278 DOI: 10.1016/j.jpba.2013.12.003  0.92
2013 Baek KH, Karki R, Lee ES, Na Y, Kwon Y. Synthesis and investigation of dihydroxychalcones as calpain and cathepsin inhibitors. Bioorganic Chemistry. 51: 24-30. PMID 24095934 DOI: 10.1016/j.bioorg.2013.09.002  0.92
2013 Abdel-Aziz M, Park SE, Abuo-Rahma Gel-D, Sayed MA, Kwon Y. Novel N-4-piperazinyl-ciprofloxacin-chalcone hybrids: synthesis, physicochemical properties, anticancer and topoisomerase I and II inhibitory activity. European Journal of Medicinal Chemistry. 69: 427-38. PMID 24090914 DOI: 10.1016/j.ejmech.2013.08.040  0.92
2013 Park SE, Chang IH, Jun KY, Lee E, Lee ES, Na Y, Kwon Y. 3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage. European Journal of Medicinal Chemistry. 69: 139-45. PMID 24013413 DOI: 10.1016/j.ejmech.2013.07.048  0.92
2013 Nam JM, Jeon KH, Kwon H, Lee E, Jun KY, Jin YB, Lee YS, Na Y, Kwon Y. Dithiiranylmethyloxy azaxanthone shows potent anti-tumor activity via suppression of HER2 expression and HER2-mediated signals in HER2-overexpressing breast cancer cells. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 50: 181-90. PMID 23835029 DOI: 10.1016/j.ejps.2013.06.014  0.92
2013 Lee KA, Kim SH, Kim EK, Ha EM, You H, Kim B, Kim MJ, Kwon Y, Ryu JH, Lee WJ. Bacterial-derived uracil as a modulator of mucosal immunity and gut-microbe homeostasis in Drosophila. Cell. 153: 797-811. PMID 23663779 DOI: 10.1016/j.cell.2013.04.009  0.92
2013 Kim SH, Lee E, Baek KH, Kwon HB, Woo H, Lee ES, Kwon Y, Na Y. Chalcones, inhibitors for topoisomerase I and cathepsin B and L, as potential anti-cancer agents. Bioorganic & Medicinal Chemistry Letters. 23: 3320-4. PMID 23608763 DOI: 10.1016/j.bmcl.2013.03.106  0.92
2013 Jeon KH, Jun KY, Kim EY, Kwon Y. Expression and purification of a soluble ESX-binding core domain of SUR2. Preparative Biochemistry & Biotechnology. 43: 364-75. PMID 23464919 DOI: 10.1080/10826068.2012.738273  0.92
2013 Lee E, Eom JE, Kim HL, Baek KH, Jun KY, Kim HJ, Lee M, Mook-Jung I, Kwon Y. Effect of conjugated linoleic acid, μ-calpain inhibitor, on pathogenesis of Alzheimer's disease. Biochimica Et Biophysica Acta. 1831: 709-18. PMID 23246577 DOI: 10.1016/j.bbalip.2012.12.003  0.92
2013 Thapa P, Jahng Y, Park PH, Jee JG, Kwon Y, Lee ES. 2,4-Diaryl benzofuro[3,2-b]pyridine derivatives: Design, synthesis, and evaluation of topoisomerase inhibitory activity and cytotoxicity Bulletin of the Korean Chemical Society. 34: 3073-3082. DOI: 10.5012/bkcs.2013.34.10.3073  0.92
2012 Liang JL, Park SE, Kwon Y, Jahng Y. Synthesis of benzo-annulated tryptanthrins and their biological properties. Bioorganic & Medicinal Chemistry. 20: 4962-7. PMID 22819942 DOI: 10.1016/j.bmc.2012.06.034  0.92
2012 Kim HL, Jeon KH, Jun KY, Choi Y, Kim DK, Na Y, Kwon Y. A-62176, a potent topoisomerase inhibitor, inhibits the expression of human epidermal growth factor receptor 2. Cancer Letters. 325: 72-9. PMID 22732416 DOI: 10.1016/j.canlet.2012.06.004  0.92
2012 Kwon Y, Sohn SH, Lee G, Kim Y, Lee H, Shin M, Bae H. Electroacupuncture Attenuates Ovalbumin-Induced Allergic Asthma via Modulating CD4(+)CD25(+) Regulatory T Cells. Evidence-Based Complementary and Alternative Medicine : Ecam. 2012: 647308. PMID 22649477 DOI: 10.1155/2012/647308  0.56
2012 Thapa P, Karki R, Yun M, Kadayat TM, Lee E, Kwon HB, Na Y, Cho WJ, Kim ND, Jeong BS, Kwon Y, Lee ES. Design, synthesis, and antitumor evaluation of 2,4,6-triaryl pyridines containing chlorophenyl and phenolic moiety. European Journal of Medicinal Chemistry. 52: 123-36. PMID 22503656 DOI: 10.1016/j.ejmech.2012.03.010  0.92
2012 Liang JL, Cha HC, Lee SH, Son JK, Chang HW, Eom JE, Kwon Y, Jahng Y. A facile synthesis of emodin derivatives, emodin carbaldehyde, citreorosein, and their 10-deoxygenated derivatives and their inhibitory activities on μ-calpain. Archives of Pharmacal Research. 35: 447-54. PMID 22477191 DOI: 10.1007/s12272-012-0307-4  0.92
2012 Lee E, Eom JE, Kim HL, Kang DH, Jun KY, Jung DS, Kwon Y. Neuroprotective effect of undecylenic acid extracted from Ricinus communis L. through inhibition of μ-calpain. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 46: 17-25. PMID 22333440 DOI: 10.1016/j.ejps.2012.01.015  0.92
2012 Karki R, Thapa P, Yoo HY, Kadayat TM, Park PH, Na Y, Lee E, Jeon KH, Cho WJ, Choi H, Kwon Y, Lee ES. Dihydroxylated 2,4,6-triphenyl pyridines: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study. European Journal of Medicinal Chemistry. 49: 219-28. PMID 22318164 DOI: 10.1016/j.ejmech.2012.01.015  0.92
2012 Thapa P, Karki R, Yoo HY, Park PH, Lee E, Jeon KH, Na Y, Cho WJ, Kwon Y, Lee ES. 2,4-Diaryl-5,6-dihydro-1,10-phenanthroline and 2,4-diaryl-5,6-dihydrothieno[2,3-h] quinoline derivatives for topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study. Bioorganic Chemistry. 40: 67-78. PMID 22000119 DOI: 10.1016/j.bioorg.2011.09.001  0.92
2012 Lee YJ, Lee E, Han AR, Song JI, Kwon Y, Seo EK. Evaluation of μ-calpain inhibitory activity of Korean indigenous marine organism extracts Natural Product Sciences. 18: 102-105.  0.92
2011 Van HT, Khadka DB, Yang SH, Le TN, Cho SH, Zhao C, Lee IS, Kwon Y, Lee KT, Kim YC, Cho WJ. Synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase I inhibitory activity, cytotoxicity and docking study. Bioorganic & Medicinal Chemistry. 19: 5311-20. PMID 21873069 DOI: 10.1016/j.bmc.2011.08.006  0.92
2011 Rhee HK, Yoo JH, Lee E, Kwon YJ, Seo HR, Lee YS, Choo HY. Synthesis and cytotoxicity of 2-phenylquinazolin-4(3H)-one derivatives. European Journal of Medicinal Chemistry. 46: 3900-8. PMID 21704436 DOI: 10.1016/j.ejmech.2011.05.061  0.92
2011 Le TN, Yang SH, Khadka DB, Van HT, Cho SH, Kwon Y, Lee ES, Lee KT, Cho WJ. Design and synthesis of 4-amino-2-phenylquinazolines as novel topoisomerase I inhibitors with molecular modeling. Bioorganic & Medicinal Chemistry. 19: 4399-404. PMID 21684168 DOI: 10.1016/j.bmc.2011.05.012  0.92
2011 Thapa U, Thapa P, Karki R, Yun M, Choi JH, Jahng Y, Lee E, Jeon KH, Na Y, Ha EM, Cho WJ, Kwon Y, Lee ES. Synthesis of 2,4-diaryl chromenopyridines and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship. European Journal of Medicinal Chemistry. 46: 3201-9. PMID 21601964 DOI: 10.1016/j.ejmech.2011.04.029  0.92
2011 Kim M, Maeng J, Jung J, Kim HY, Kim HJ, Kwon Y, Lee K. Design and evaluation of variants of the protein transduction domain originated from translationally controlled tumor protein. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 43: 25-31. PMID 21440624 DOI: 10.1016/j.ejps.2011.03.007  0.92
2011 Sapkota K, Roh E, Lee E, Ha EM, Yang JH, Lee ES, Kwon Y, Kim Y, Na Y. Synthesis and anti-melanogenic activity of hydroxyphenyl benzyl ether analogues. Bioorganic & Medicinal Chemistry. 19: 2168-75. PMID 21429753 DOI: 10.1016/j.bmc.2011.02.044  0.92
2011 Jun KY, Lee EY, Jung MJ, Lee OH, Lee ES, Park Choo HY, Na Y, Kwon Y. Synthesis, biological evaluation, and molecular docking study of 3-(3'-heteroatom substituted-2'-hydroxy-1'-propyloxy) xanthone analogues as novel topoisomerase IIα catalytic inhibitor. European Journal of Medicinal Chemistry. 46: 1964-71. PMID 21419530 DOI: 10.1016/j.ejmech.2011.01.011  0.92
2011 Kim M, Chung J, Lee C, Jung J, Kwon Y, Lee K. A peptide binding to dimerized translationally controlled tumor protein modulates allergic reactions. Journal of Molecular Medicine (Berlin, Germany). 89: 603-10. PMID 21384150 DOI: 10.1007/s00109-011-0740-8  0.92
2011 Khadka DB, Le QM, Yang SH, Van HT, Le TN, Cho SH, Kwon Y, Lee KT, Lee ES, Cho WJ. Design, synthesis and docking study of 5-amino substituted indeno[1,2-c]isoquinolines as novel topoisomerase I inhibitors. Bioorganic & Medicinal Chemistry. 19: 1924-9. PMID 21353568 DOI: 10.1016/j.bmc.2011.01.064  0.92
2011 Lee E, Seo EY, Kwon Y, Ha H. Rapid and reliable measurement for evaluating directly the reactivity of N-acetylcysteine with glucose degradation products in peritoneal dialysis fluids. Analytical Chemistry. 83: 1518-22. PMID 21299245 DOI: 10.1021/ac200046y  0.92
2011 Lee E, Jang I, Shin MJ, Cho HJ, Kim J, Eom JE, Kwon Y, Na Y. Chalcones as novel non-peptidic μ-calpain inhibitors Bulletin of the Korean Chemical Society. 32: 3459-3464. DOI: 10.5012/bkcs.2011.32.9.3459  0.92
2011 Rhee HK, Kwon Y, Chung HJ, Lee SK, Choo HYP. Synthesis, cytotoxicity and topoisomerase II inhibitory activity of benzonaphthofurandiones Bulletin of the Korean Chemical Society. 32: 2391-2396. DOI: 10.5012/bkcs.2011.32.7.2391  0.92
2011 Jeong BS, Choi H, Thapa P, Karki R, Lee E, Nam JM, Na Y, Ha EM, Kwon Y, Lee ES. Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety Bulletin of the Korean Chemical Society. 32: 303-306. DOI: 10.5012/bkcs.2011.32.1.303  0.92
2010 Lee H, Lee H, Kwon Y, Lee JH, Kim J, Shin MK, Kim SH, Bae H. Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 6698-705. PMID 21048105 DOI: 10.4049/jimmunol.1001373  0.56
2010 Hong YH, Lee WJ, Lee SH, Son JK, Kim HL, Nam JM, Kwon Y, Jahng Y. Synthesis and biological properties of benzo-annulated rutaecarpines. Biological & Pharmaceutical Bulletin. 33: 1704-9. PMID 20930379 DOI: JST.JSTAGE/bpb/33.1704  0.92
2010 Woo S, Kang DH, Nam JM, Lee CS, Ha EM, Lee ES, Kwon Y, Na Y. Synthesis and pharmacological evaluation of new methyloxiranylmethoxyxanthone analogues. European Journal of Medicinal Chemistry. 45: 4221-8. PMID 20619511 DOI: 10.1016/j.ejmech.2010.06.017  0.92
2010 Choi Y, Jeon S, Choi M, Lee MH, Park M, Lee DR, Jun KY, Kwon Y, Lee OH, Song SH, Kim JY, Lee KA, Yoon TK, Rajkovic A, Shim SH. Mutations in SOHLH1 gene associate with nonobstructive azoospermia. Human Mutation. 31: 788-93. PMID 20506135 DOI: 10.1002/humu.21264  0.92
2010 Karki R, Thapa P, Kang MJ, Jeong TC, Nam JM, Kim HL, Na Y, Cho WJ, Kwon Y, Lee ES. Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of hydroxylated 2,4-diphenyl-6-aryl pyridines. Bioorganic & Medicinal Chemistry. 18: 3066-77. PMID 20392646 DOI: 10.1016/j.bmc.2010.03.051  0.92
2010 Thapa P, Karki R, Choi H, Choi JH, Yun M, Jeong BS, Jung MJ, Nam JM, Na Y, Cho WJ, Kwon Y, Lee ES. Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship. Bioorganic & Medicinal Chemistry. 18: 2245-54. PMID 20188578 DOI: 10.1016/j.bmc.2010.01.065  0.92
2010 Cho HJ, Jung MJ, Woo S, Kim J, Lee ES, Kwon Y, Na Y. New benzoxanthone derivatives as topoisomerase inhibitors and DNA cross-linkers. Bioorganic & Medicinal Chemistry. 18: 1010-7. PMID 20093033 DOI: 10.1016/j.bmc.2009.12.069  0.92
2010 Basnet A, Thapa P, Karki R, Choi H, Choi JH, Yun M, Jeong BS, Jahng Y, Na Y, Cho WJ, Kwon Y, Lee CS, Lee ES. 2,6-Dithienyl-4-furyl pyridines: Synthesis, topoisomerase I and II inhibition, cytotoxicity, structure-activity relationship, and docking study. Bioorganic & Medicinal Chemistry Letters. 20: 42-7. PMID 19954977 DOI: 10.1016/j.bmcl.2009.11.041  0.92
2010 Thapa P, Karki R, Thapa U, Jahng Y, Jung MJ, Nam JM, Na Y, Kwon Y, Lee ES. 2-Thienyl-4-furyl-6-aryl pyridine derivatives: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study. Bioorganic & Medicinal Chemistry. 18: 377-86. PMID 19939682 DOI: 10.1016/j.bmc.2009.10.049  0.92
2010 Karki R, Thapa P, Kwon Y, Lee ES. Synthesis, topoisomerase i and II inhibitory activities, and cytotoxicity of 4,6-diaryl-2,4'-bipyridine derivatives Bulletin of the Korean Chemical Society. 31: 1747-1750. DOI: 10.5012/bkcs.2010.31.6.1747  0.92
2010 Sapkota K, Lee E, Yang JH, Kwon Y, Choi J, Na Y. 4-Hydroxy-2'-nitrodiphenyl ether analogues as novel tyrosinase inhibitors Bulletin of the Korean Chemical Society. 31: 1319-1325. DOI: 10.5012/bkcs.2010.31.5.1319  0.92
2009 Cho HJ, Jung MJ, Kwon Y, Na Y. Oxiranylmethyloxy or thiiranylmethyloxy-azaxanthones and -acridone analogues as potential topoisomerase I inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 6766-9. PMID 19836231 DOI: 10.1016/j.bmcl.2009.09.091  0.92
2009 Rhee HK, Lim SY, Jung MJ, Kwon Y, Kim MH, Choo HY. Synthesis of isoquinolinone-based tetracycles as poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors. Bioorganic & Medicinal Chemistry. 17: 7537-41. PMID 19800803 DOI: 10.1016/j.bmc.2009.09.014  0.92
2009 Kamisuki S, Mao Q, Abu-Elheiga L, Gu Z, Kugimiya A, Kwon Y, Shinohara T, Kawazoe Y, Sato S, Asakura K, Choo HY, Sakai J, Wakil SJ, Uesugi M. A small molecule that blocks fat synthesis by inhibiting the activation of SREBP. Chemistry & Biology. 16: 882-92. PMID 19716478 DOI: 10.1016/j.chembiol.2009.07.007  0.92
2009 Na Y, Cha JH, Yoon HG, Kwon Y. A concise synthesis of licochalcone E and its regio-isomer, licochalcone F. Chemical & Pharmaceutical Bulletin. 57: 607-9. PMID 19483343 DOI: JST.JSTAGE/cpb/57.607  0.92
2009 Kang DH, Jun KY, Lee JP, Pak CS, Na Y, Kwon Y. Identification of 3-acetyl-2-aminoquinolin-4-one as a novel, nonpeptidic scaffold for specific calpain inhibitory activity. Journal of Medicinal Chemistry. 52: 3093-7. PMID 19419206 DOI: 10.1021/jm8014734  0.92
2009 Lee SH, Van HT, Yang SH, Lee KT, Kwon Y, Cho WJ. Molecular design, synthesis and docking study of benz[b]oxepines and 12-oxobenzo[c]phenanthridinones as topoisomerase 1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 2444-7. PMID 19345580 DOI: 10.1016/j.bmcl.2009.03.058  0.92
2009 Jung D, Shimogawa H, Kwon Y, Mao Q, Sato S, Kamisuki S, Kigoshi H, Uesugi M. Wrenchnolol derivative optimized for gene activation in cells. Journal of the American Chemical Society. 131: 4774-82. PMID 19290630 DOI: 10.1021/ja900669k  0.92
2009 Jung MJ, Yang DH, Sung YK, Kim MJ, Kang SJ, Kwon DY, Kwon Y. Rapid determination of trace methylmercury in natural crude medicine of animal origin Microchimica Acta. 164: 345-349. DOI: 10.1007/s00604-008-0063-9  0.92
2008 Hashem MA, Jun KY, Lee E, Lim S, Choo HY, Kwon Y. A rapid and sensitive screening system for human type I collagen with the aim of discovering potent anti-aging or anti-fibrotic compounds. Molecules and Cells. 26: 625-30. PMID 18810249  0.92
2008 Motiur Rahman AF, Liang JL, Lee SH, Son JK, Jung MJ, Kwon Y, Jahng Y. 2,2-dimethyl-2H-pyran-derived alkaloids I. Practical synthesis of acronycine and benzo[b]acronycine and their biological properties. Archives of Pharmacal Research. 31: 1087-93. PMID 18806949 DOI: 10.1007/s12272-001-1273-7  0.92
2008 Kang DH, Kim JS, Jung MJ, Lee ES, Jahng Y, Kwon Y, Na Y. New insight for fluoroquinophenoxazine derivatives as possibly new potent topoisomerase I inhibitor. Bioorganic & Medicinal Chemistry Letters. 18: 1520-4. PMID 18178085 DOI: 10.1016/j.bmcl.2007.12.053  0.92
2008 Jeong LS, Tosh DK, Kim HO, Wang T, Hou X, Yun HS, Kwon Y, Lee SK, Choi J, Zhao LX. First synthesis of 4'-selenonucleosides showing unusual Southern conformation. Organic Letters. 10: 209-12. PMID 18088134 DOI: 10.1021/ol7025558  0.92
2008 Rahman AFMM, Dong HK, Jing LL, Lee ES, Na Y, Jun KY, Kwon Y, Jahng Y. Synthesis and Biological Properties of Luotonin a Derivatives Bulletin of the Korean Chemical Society. 29: 1988-1992.  0.92
2008 Thapa P, Karki R, Basnet A, Thapa U, Choi H, Na Y, Jahng Y, Lee CS, Kwon Y, Jeong BS, Lee ES. 2,6-Dithienyl-4-arylpyridines: Synthesis, topoisomerase I and II inhibition and structure-activity relationship Bulletin of the Korean Chemical Society. 29: 1605-1608.  0.92
2008 Woo S, Kang DH, Kim J, Lee CS, Lee ES, Jahng Y, Kwon Y, Na Y. Synthesis, cytotoxicity and topoisomerase II inhibition study of new thioxanthone analogues Bulletin of the Korean Chemical Society. 29: 471-474.  0.92
2007 Van HT, Le QM, Lee KY, Lee ES, Kwon Y, Kim TS, Le TN, Lee SH, Cho WJ. Convenient synthesis of indeno[1,2-c]isoquinolines as constrained forms of 3-arylisoquinolines and docking study of a topoisomerase I inhibitor into DNA-topoisomerase I complex. Bioorganic & Medicinal Chemistry Letters. 17: 5763-7. PMID 17827007 DOI: 10.1016/j.bmcl.2007.08.062  0.92
2007 Cho WJ, Le QM, My Van HT, Youl Lee K, Kang BY, Lee ES, Lee SK, Kwon Y. Design, docking, and synthesis of novel indeno[1,2-c]isoquinolines for the development of antitumor agents as topoisomerase I inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 3531-4. PMID 17498951 DOI: 10.1016/j.bmcl.2007.04.064  0.92
2007 Chung SY, Jang DS, Han AR, Jang JO, Kwon Y, Seo EK, Lee HJ. Modulation of P-glycoprotein-mediated resistance by kaempferol derivatives isolated from Zingiber zerumbet. Phytotherapy Research : Ptr. 21: 565-9. PMID 17335117 DOI: 10.1002/ptr.2113  0.92
2007 Jeong YH, Chung SY, Han AR, Sung MK, Jang DS, Lee J, Kwon Y, Lee HJ, Seo EK. P-glycoprotein inhibitory activity of two phenolic compounds, (-)-syringaresinol and tricin from Sasa borealis. Chemistry & Biodiversity. 4: 12-6. PMID 17256728 DOI: 10.1002/cbdv.200790001  0.92
2007 Sato S, Kwon Y, Kamisuki S, Srivastava N, Mao Q, Kawazoe Y, Uesugi M. Polyproline-rod approach to isolating protein targets of bioactive small molecules: isolation of a new target of indomethacin. Journal of the American Chemical Society. 129: 873-80. PMID 17243824 DOI: 10.1021/ja0655643  0.92
2007 Woo S, Jung J, Lee C, Kwon Y, Na Y. Synthesis of new xanthone analogues and their biological activity test--cytotoxicity, topoisomerase II inhibition, and DNA cross-linking study. Bioorganic & Medicinal Chemistry Letters. 17: 1163-6. PMID 17194586 DOI: 10.1016/j.bmcl.2006.12.030  0.92
2006 Kwon Y, Na Y. Study on the synthesis and cytotoxicity of new quinophenoxazine derivatives. Chemical & Pharmaceutical Bulletin. 54: 248-51. PMID 16462076 DOI: JST.JSTAGE/cpb/54.248  0.92
2006 Kwon Y. Studies on the binding affinity of aminoglycoside antibiotics to the HIV-1 Rev Responsive Element for designing potential antiviral agents Journal of Microbiology and Biotechnology. 16: 109-117.  0.92
2005 Rahman AFMM, Kwon Y, Jahng Y. Friedländer reactions of triacetylmethane- unusual distribution of products- Heterocycles. 65: 2777-2782. DOI: 10.3987/COM-05-10534  0.92
2005 Li G, Cui JM, Kwon Y, Seo CS, Lee CS, Woo MH, Eung SL, Jahng Y, Chang HW, Lee SH, Son JK. Two new diarylheptanoids from Juglans mandshurica Bulletin of the Korean Chemical Society. 26: 1878-1880.  0.92
2005 Jeong YH, Nam JW, Lee NY, Seo EK, Kwon Y. Isolation and structural identification of minor constituents from Sasa borealis Natural Product Sciences. 11: 170-173.  0.92
2004 Kwon Y, Arndt HD, Mao Q, Choi Y, Kawazoe Y, Dervan PB, Uesugi M. Small molecule transcription factor mimic. Journal of the American Chemical Society. 126: 15940-1. PMID 15584709 DOI: 10.1021/ja0445140  0.92
2004 Shimogawa H, Kwon Y, Mao Q, Kawazoe Y, Choi Y, Asada S, Kigoshi H, Uesugi M. A wrench-shaped synthetic molecule that modulates a transcription factor-coactivator interaction. Journal of the American Chemical Society. 126: 3461-71. PMID 15025473 DOI: 10.1021/ja038855+  0.92
2003 Kwon Y, Xi Z, Kappen LS, Goldberg IH, Gao X. New complex of post-activated neocarzinostatin chromophore with DNA: bulge DNA binding from the minor groove. Biochemistry. 42: 1186-98. PMID 12564921 DOI: 10.1021/bi0206210  0.36
2002 Gao X, Stassinopoulos A, Ji J, Kwon Y, Bare S, Goldberg IH. Induced formation of a DNA bulge structure by a molecular wedge ligand-postactivated neocarzinostatin chromophore. Biochemistry. 41: 5131-43. PMID 11955061  0.36
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