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Sundari K. Rallapalli, Ph.D. - Publications

Affiliations: 
2012 Chemistry University of Wisconsin-Milwaukee, Milwaukee, WI 
Area:
Alkaloid total synthesis
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Rahman MT, Tiruveedhula VVNPB, Stephen MR, Rallapalli SK, Pandey KP, Cook JM. Completion of the Total Synthesis of Several Bioactive Sarpagine/Macroline Alkaloids including the Important NF-κB Inhibitor -Methyltalpinine. Molecules (Basel, Switzerland). 27. PMID 35268836 DOI: 10.3390/molecules27051738  0.752
2015 Clayton T, Poe MM, Rallapalli S, Biawat P, Savić MM, Rowlett JK, Gallos G, Emala CW, Kaczorowski CC, Stafford DC, Arnold LA, Cook JM. A Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor Model. International Journal of Medicinal Chemistry. 2015: 430248. PMID 26682068 DOI: 10.1155/2015/430248  0.73
2015 Fischer BD, Platt DM, Rallapalli SK, Namjoshi OA, Cook JM, Rowlett JK. Antagonism of triazolam self-administration in rhesus monkeys responding under a progressive-ratio schedule: In vivo apparent pA2 analysis. Drug and Alcohol Dependence. PMID 26596587 DOI: 10.1016/J.Drugalcdep.2015.10.026  0.541
2014 Hackett CS, Quigley DA, Wong RA, Chen J, Cheng C, Song YK, Wei JS, Pawlikowska L, Bao Y, Goldenberg DD, Nguyen K, Gustafson WC, Rallapalli SK, Cho YJ, Cook JM, et al. Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma. Cell Reports. 9: 1034-46. PMID 25437558 DOI: 10.1016/J.Celrep.2014.09.046  0.498
2014 Rallapalli SK, Namjoshi OA, Tiruveedhula VV, Deschamps JR, Cook JM. Stereospecific total synthesis of the indole alkaloid ervincidine. Establishment of the C-6 hydroxyl stereochemistry. The Journal of Organic Chemistry. 79: 3776-80. PMID 24697213 DOI: 10.1021/Jo402692U  0.412
2014 Rae CD, Davidson JE, Maher AD, Rowlands BD, Kashem MA, Nasrallah FA, Rallapalli SK, Cook JM, Balcar VJ. Ethanol, not detectably metabolized in brain, significantly reduces brain metabolism, probably via action at specific GABA(A) receptors and has measureable metabolic effects at very low concentrations. Journal of Neurochemistry. 129: 304-14. PMID 24313287 DOI: 10.1111/Jnc.12634  0.49
2014 Sengupta S, Weeraratne SD, Sun H, Phallen J, Rallapalli SK, Teider N, Kosaras B, Amani V, Pierre-Francois J, Tang Y, Nguyen B, Yu F, Schubert S, Balansay B, Mathios D, et al. α5-GABAA receptors negatively regulate MYC-amplified medulloblastoma growth. Acta Neuropathologica. 127: 593-603. PMID 24196163 DOI: 10.1007/S00401-013-1205-7  0.505
2013 Soto PL, Ator NA, Rallapalli SK, Biawat P, Clayton T, Cook JM, Weed MR. Allosteric modulation of GABA(A) receptor subtypes:effects on visual recognition and visuospatial working memory in rhesus monkeys [corrected]. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2315-25. PMID 23722241 DOI: 10.1038/Npp.2013.137  0.476
2013 Joksimović S, Varagic Z, Kovačević J, Van Linn M, Milić M, Rallapalli S, Timić T, Sieghart W, Cook JM, Savić MM. Insights into functional pharmacology of α₁ GABA(A) receptors: how much does partial activation at the benzodiazepine site matter? Psychopharmacology. 230: 113-23. PMID 23685860 DOI: 10.1007/S00213-013-3143-4  0.778
2013 Varagic Z, Ramerstorfer J, Huang S, Rallapalli S, Sarto-Jackson I, Cook J, Sieghart W, Ernst M. Subtype selectivity of α+β- site ligands of GABAA receptors: identification of the first highly specific positive modulators at α6β2/3γ2 receptors. British Journal of Pharmacology. 169: 384-99. PMID 23472935 DOI: 10.1111/Bph.12153  0.757
2013 Varagic Z, Wimmer L, Schnürch M, Mihovilovic MD, Huang S, Rallapalli S, Cook JM, Mirheydari P, Ecker GF, Sieghart W, Ernst M. Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β- interface. British Journal of Pharmacology. 169: 371-83. PMID 23472852 DOI: 10.1111/Bph.12151  0.747
2013 Makaron L, Moran CA, Namjoshi O, Rallapalli S, Cook JM, Rowlett JK. Cognition-impairing effects of benzodiazepine-type drugs: role of GABAA receptor subtypes in an executive function task in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 104: 62-8. PMID 23290931 DOI: 10.1016/J.Pbb.2012.12.018  0.494
2013 Milić M, Timić T, Joksimović S, Biawat P, Rallapalli S, Divljaković J, Radulović T, Cook JM, Savić MM. PWZ-029, an inverse agonist selective for α₅ GABAA receptors, improves object recognition, but not water-maze memory in normal and scopolamine-treated rats. Behavioural Brain Research. 241: 206-13. PMID 23261875 DOI: 10.1016/J.Bbr.2012.12.016  0.529
2013 Namjoshi OA, Wang ZJ, Rallapalli SK, Johnson EM, Johnson YT, Ng H, Ramerstorfer J, Varagic Z, Sieghart W, Majumder S, Roth BL, Rowlett JK, Cook JM. Search for α3β₂/₃γ2 subtype selective ligands that are stable on human liver microsomes. Bioorganic & Medicinal Chemistry. 21: 93-101. PMID 23218469 DOI: 10.1016/J.Bmc.2012.10.057  0.649
2013 Rüedi-Bettschen D, Rowlett JK, Rallapalli S, Clayton T, Cook JM, Platt DM. Modulation of α5 subunit-containing GABAA receptors alters alcohol drinking by rhesus monkeys. Alcoholism, Clinical and Experimental Research. 37: 624-34. PMID 23126673 DOI: 10.1111/Acer.12018  0.479
2013 Soto PL, Ator NA, Rallapalli SK, Biawat P, Clayton T, Cook JM, Weed MR. Erratum: Allosteric Modulation of GABAA Receptor Subtypes: Effects on Visual Recognition and Visuospatial Working Memory in Rhesus Monkeys Neuropsychopharmacology. 38: 2553-2553. DOI: 10.1038/Npp.2013.162  0.448
2012 Milić M, Divljaković J, Rallapalli S, van Linn ML, Timić T, Cook JM, Savić MM. The role of α1 and α5 subunit-containing GABAA receptors in motor impairment induced by benzodiazepines in rats. Behavioural Pharmacology. 23: 191-7. PMID 22327019 DOI: 10.1097/Fbp.0B013E3283512C85  0.762
2011 Iyer SV, Benavides RA, Chandra D, Cook JM, Rallapalli S, June HL, Homanics GE. α4-Containing GABA(A) Receptors are Required for Antagonism of Ethanol-Induced Motor Incoordination and Hypnosis by the Imidazobenzodiazepine Ro15-4513. Frontiers in Pharmacology. 2: 18. PMID 21779248 DOI: 10.3389/Fphar.2011.00018  0.432
2010 Yin W, Kabir MS, Wang Z, Rallapalli SK, Ma J, Cook JM. Enantiospecific total synthesis of the important biogenetic intermediates along the ajmaline pathway, (+)-polyneuridine and (+)-polyneuridine aldehyde, as well as 16-epivellosimine and macusine A. The Journal of Organic Chemistry. 75: 3339-49. PMID 20392128 DOI: 10.1021/Jo100279W  0.724
2010 Yang J, Rallapalli SK, Cook JM. The first enantiospecific total synthesis of the 3-oxygenated sarpagine indole alkaloids affinine and 16-epiaffinine, as well as vobasinediol and 16-epivobasinediol Tetrahedron Letters. 51: 815-817. DOI: 10.1016/J.Tetlet.2009.12.002  0.46
2009 Yang J, Teng Y, Ara S, Rallapalli S, Cook JM. An Improved Process for the Synthesis of 4H-Imidazo[1,5-a][1,4]benzodiazepines. Synthesis. 40: nihpa145687. PMID 19936036 DOI: 10.1055/S-0028-1083358  0.448
2009 Edwankar CR, Edwankar RV, Namjoshi OA, Rallapalli SK, Yang J, Cook JM. Recent progress in the total synthesis of indole alkaloids. Current Opinion in Drug Discovery & Development. 12: 752-71. PMID 19894188  0.702
2009 Savić MM, Milinković MM, Rallapalli S, Clayton T, Joksimović S, Van Linn M, Cook JM. The differential role of alpha1- and alpha5-containing GABA(A) receptors in mediating diazepam effects on spontaneous locomotor activity and water-maze learning and memory in rats. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 1179-93. PMID 19265570 DOI: 10.1017/S1461145709000108  0.764
2009 Yang J, Teng Y, Ara S, Rallapalli S, Cook JM. An improved process for the synthesis of 4H-imidazo[1,5-a][1,4] benzodiazepines Synthesis. 1036-1040. DOI: 10.1055/s-0028-1083358  0.358
2008 Han D, Holger Försterling F, Li X, Deschamps JR, Parrish D, Cao H, Rallapalli S, Clayton T, Teng Y, Majumder S, Sankar S, Roth BL, Sieghart W, Furtmuller R, Rowlett JK, et al. A study of the structure-activity relationship of GABA(A)-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis. Bioorganic & Medicinal Chemistry. 16: 8853-62. PMID 18790643 DOI: 10.1016/J.Bmc.2008.08.072  0.615
2008 Edwankar CR, Edwankar RV, Rallapalli S, Cook JM. General approach to the total synthesis of macroline-related sarpagine and ajmaline alkaloids Natural Product Communications. 3: 1839-1870. DOI: 10.1177/1934578X0800301114  0.691
2008 Samardzic J, Savic MM, Clayton T, Rallapalli S, Obradovic DI, Joksimovic SM, Sieghart W, Cook JM. P.1.g.021 Effects of a novel inverse agonist selective for alpha5 GABAA receptors on spatial memory: comparison with the standard non-selective inverse agonist DMCM European Neuropsychopharmacology. 18. DOI: 10.1016/S0924-977X(08)70377-8  0.363
2008 Milinkovic MM, Savic MM, Rallapalli S, Samardzic J, Linn MV, Ugresic N, Cook JM. P.1.g.019 RY-023, an inverse agonist at alpha5 GABAA receptors: the influence on spatial memory and spontaneous locomotor activity European Neuropsychopharmacology. 18. DOI: 10.1016/S0924-977X(08)70375-4  0.318
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