Thomas H. Charpentier, Ph.D. - Publications

2009 Biochemistry University of Maryland School of Medicine, Baltimore, MD, United States 
structure and function of S100B, a growth factor in the brain and skin

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Cavalier MC, Ansari MI, Pierce AD, Wilder PT, McKnight LE, Raman EP, Neau DB, Bezawada P, Alasady MJ, Charpentier TH, Varney K, Toth EA, MacKerell AD, Coop A, Weber DJ. Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations. Journal of Medicinal Chemistry. PMID 26727270 DOI: 10.1021/Acs.Jmedchem.5B01369  1
2014 Charpentier TH, Waldo GL, Barrett MO, Huang W, Zhang Q, Harden TK, Sondek J. Membrane-induced allosteric control of phospholipase C-β isozymes. The Journal of Biological Chemistry. 289: 29545-57. PMID 25193662 DOI: 10.1074/Jbc.M114.586784  1
2014 Schmitz AL, Schrage R, Gaffal E, Charpentier TH, Wiest J, Hiltensperger G, Morschel J, Hennen S, Häußler D, Horn V, Wenzel D, Grundmann M, Büllesbach KM, Schröder R, Brewitz HH, et al. A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation. Chemistry & Biology. 21: 890-902. PMID 25036778 DOI: 10.1016/J.Chembiol.2014.06.003  1
2013 Hajicek N, Charpentier TH, Rush JR, Harden TK, Sondek J. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes. Biochemistry. 52: 4810-9. PMID 23777354 DOI: 10.1021/Bi400433B  1
2010 Wilder PT, Charpentier TH, Liriano MA, Gianni K, Varney KM, Pozharski E, Coop A, Toth EA, Mackerell AD, Weber DJ. In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction. International Journal of High Throughput Screening. 2010: 109-126. PMID 21132089 DOI: 10.2147/IJHTS.S8210  1
2010 Charpentier TH, Thompson LE, Liriano MA, Varney KM, Wilder PT, Pozharski E, Toth EA, Weber DJ. The effects of CapZ peptide (TRTK-12) binding to S100B-Ca2+ as examined by NMR and X-ray crystallography. Journal of Molecular Biology. 396: 1227-43. PMID 20053360 DOI: 10.1016/J.Jmb.2009.12.057  1
2009 Charpentier TH, Wilder PT, Liriano MA, Varney KM, Zhong S, Coop A, Pozharski E, MacKerell AD, Toth EA, Weber DJ. Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography. Biochemistry. 48: 6202-12. PMID 19469484 DOI: 10.1021/Bi9005754  1
2008 Charpentier TH, Wilder PT, Liriano MA, Varney KM, Pozharski E, MacKerell AD, Coop A, Toth EA, Weber DJ. Divalent metal ion complexes of S100B in the absence and presence of pentamidine. Journal of Molecular Biology. 382: 56-73. PMID 18602402 DOI: 10.1016/J.Jmb.2008.06.047  1
2008 Malashkevich VN, Varney KM, Garrett SC, Wilder PT, Knight D, Charpentier TH, Ramagopal UA, Almo SC, Weber DJ, Bresnick AR. Structure of Ca2+-bound S100A4 and its interaction with peptides derived from nonmuscle myosin-IIA. Biochemistry. 47: 5111-26. PMID 18410126 DOI: 10.1021/Bi702537S  1
2007 Blaustein MP, Charpentier TH, Weber DJ. Getting a grip on calcium regulation. Proceedings of the National Academy of Sciences of the United States of America. 104: 18349-50. PMID 18003903 DOI: 10.1073/Pnas.0709008104  1
2007 Wilder PT, Charpentier TH, Weber DJ. Hydrocarbon-stapled helices: a novel approach for blocking protein-protein interactions. Chemmedchem. 2: 1149-51. PMID 17554748 DOI: 10.1002/Cmdc.200700102  1
2007 Charpentier TH, Wilder PT, Varney KM, Toth EA, Weber DJ. The 3D structures of Ca 2+ ‐S100B in Zn 2+ ‐ and pentamidine‐bound complexes as determined by X‐ray crystallography The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A630-A  1
2006 Wilder PT, Lin J, Bair CL, Charpentier TH, Yang D, Liriano M, Varney KM, Lee A, Oppenheim AB, Adhya S, Carrier F, Weber DJ. Recognition of the tumor suppressor protein p53 and other protein targets by the calcium-binding protein S100B. Biochimica Et Biophysica Acta. 1763: 1284-97. PMID 17010455 DOI: 10.1016/J.Bbamcr.2006.08.024  1
2005 Markowitz J, Mackerell AD, Carrier F, Charpentier TH, Weber DJ. Design of Inhibitors for S100B. Current Topics in Medicinal Chemistry. 5: 1093-108. PMID 16248785 DOI: 10.2174/156802605774370865  1
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