Luis A. Ralat, Ph.D. - Publications

2008 Chemistry and Biochemistry University of Delaware, Newark, DE, United States 
enzyme active sites

11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Zhou S, Sorokina EM, Harper S, Li H, Ralat L, Dodia C, Speicher DW, Feinstein SI, Fisher AB. Peroxiredoxin 6 homodimerization and heterodimerization with glutathione S-transferase pi are required for its peroxidase but not phospholipase A2 activity. Free Radical Biology & Medicine. PMID 26891882 DOI: 10.1016/j.freeradbiomed.2016.02.012  1
2011 Ralat LA, Kalas V, Zheng Z, Goldman RD, Sosnick TR, Tang WJ. Ubiquitin is a novel substrate for human insulin-degrading enzyme. Journal of Molecular Biology. 406: 454-66. PMID 21185309 DOI: 10.1016/j.jmb.2010.12.026  1
2011 Ralat LA, Guo Q, Ren M, Funke T, Dickey DM, Potter LR, Tang WJ. Insulin-degrading enzyme modulates the natriuretic peptide-mediated signaling response. The Journal of Biological Chemistry. 286: 4670-9. PMID 21098034 DOI: 10.1074/jbc.M110.173252  1
2009 Ralat LA, Ren M, Schilling AB, Tang WJ. Protective role of Cys-178 against the inactivation and oligomerization of human insulin-degrading enzyme by oxidation and nitrosylation. The Journal of Biological Chemistry. 284: 34005-18. PMID 19808678 DOI: 10.1074/jbc.M109.030627  1
2009 Hulse RE, Ralat LA, Wei-Jen T. Structure, function, and regulation of insulin-degrading enzyme. Vitamins and Hormones. 80: 635-48. PMID 19251053 DOI: 10.1016/S0083-6729(08)00622-5  1
2008 Malito E, Ralat LA, Manolopoulou M, Tsay JL, Wadlington NL, Tang WJ. Molecular bases for the recognition of short peptide substrates and cysteine-directed modifications of human insulin-degrading enzyme. Biochemistry. 47: 12822-34. PMID 18986166 DOI: 10.1021/bi801192h  1
2008 Ralat LA, Misquitta SA, Manevich Y, Fisher AB, Colman RF. Characterization of the complex of glutathione S-transferase pi and 1-cysteine peroxiredoxin. Archives of Biochemistry and Biophysics. 474: 109-18. PMID 18358825 DOI: 10.1016/  1
2006 Ralat LA, Colman RF. Identification of tyrosine 79 in the tocopherol binding site of glutathione S-transferase pi. Biochemistry. 45: 12491-9. PMID 17029404 DOI: 10.1021/bi061330k  1
2006 Ralat LA, Manevich Y, Fisher AB, Colman RF. Direct evidence for the formation of a complex between 1-cysteine peroxiredoxin and glutathione S-transferase pi with activity changes in both enzymes. Biochemistry. 45: 360-72. PMID 16401067 DOI: 10.1021/bi0520737  1
2004 Ralat LA, Colman RF. Glutathione S-transferase Pi has at least three distinguishable xenobiotic substrate sites close to its glutathione-binding site. The Journal of Biological Chemistry. 279: 50204-13. PMID 15347687 DOI: 10.1074/jbc.M407445200  1
2003 Ralat LA, Colman RF. Monobromobimane occupies a distinct xenobiotic substrate site in glutathione S-transferase pi. Protein Science : a Publication of the Protein Society. 12: 2575-87. PMID 14573868 DOI: 10.1110/ps.03249303  1
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