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Michael J. Rozema - Publications

Affiliations: 
AbbVie 
Area:
Process R&D
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Wang Z, Richter SM, Rozema MJ, Schellinger A, Smith K, Napolitano JG. Potential Safety Hazards Associated with Using Acetonitrile and a Strong Aqueous Base Organic Process Research & Development. 21: 1501-1508. DOI: 10.1021/Acs.Oprd.7B00158  0.368
2013 Wang Z, Richter SM, Gandarilla J, Kruger AW, Rozema MJ. Safe Scale-Up of a Hydrazine Condensation by the Addition of a Base Organic Process Research and Development. 17: 1603-1610. DOI: 10.1021/Op4002577  0.338
2009 McDermott TS, Bhagavatula L, Borchardt TB, Engstrom KM, Gandarilla J, Kotecki BJ, Kruger AW, Rozema MJ, Sheikh AY, Wagaw SH, Wittenberger SJ. Development of a scalable synthesis of dipeptidyl peptidase-4 inhibitor ABT-279 Organic Process Research and Development. 13: 1145-1155. DOI: 10.1021/Op900197R  0.363
2006 Rozema MJ, Fickes M, McLaughlin M, Rohde B, McDermott T. Enantioselective synthesis of the farnesyltransferase inhibitor, A-345665.0 Tetrahedron Letters. 47: 8765-8768. DOI: 10.1016/J.Tetlet.2006.10.008  0.402
2005 Rozema MJ, Kruger AW, Rohde BD, Shelat B, Bhagavatula L, Tien JJ, Zhang W, Henry RF. Synthesis of a novel farnesyl transferase inhibitor, ABT-100; Selective preparation of a stereogenic tertiary carbinol Tetrahedron. 61: 4419-4425. DOI: 10.1016/j.tet.2005.02.072  0.368
2003 Ku YY, Grieme T, Raje P, Sharma P, Morton HE, Rozema M, King SA. A practical and scaleable synthesis of A-224817.0, a novel nonsteroidal ligand for the glucocorticoid receptor. The Journal of Organic Chemistry. 68: 3238-40. PMID 12688796 DOI: 10.1021/jo0268613  0.303
1997 Hanessian S, Griffin AM, Rozema MJ. Tricyclic β-lactams: Total synthesis and antibacterial activity of 5α-methoxyethyl and 5α-hydroxyethyl trinems Bioorganic and Medicinal Chemistry Letters. 7: 1857-1862. DOI: 10.1016/S0960-894X(97)00326-0  0.408
1996 Hanessian S, Rozema MJ. A highly stereoselective and practical total synthesis of the tricyclic β-lactam antibiotic GV104326 (4-methoxytrinem) Journal of the American Chemical Society. 118: 9884-9891. DOI: 10.1021/Ja962006N  0.429
1995 Hanessian S, Rozema MJ, Reddy GB, Braganza JF. Tricyclic β-lactams: total synthesis and antibacterial activity of 5α- and 5β-methoxy-tribactams Bioorganic and Medicinal Chemistry Letters. 5: 2535-2540. DOI: 10.1016/0960-894X(95)00445-Y  0.416
1994 Hanessian S, Rozema MJ. Synthesis and biological evaluation of 1-substituted-7-(1-hydroxyethyl) carbacephems - a class of "hybrid" bicyclic β-lactams Bioorganic and Medicinal Chemistry Letters. 4: 2279-2284. DOI: 10.1016/0960-894X(94)85025-9  0.443
1993 Sidduri A, Rozema MJ, Knochel P. Selective mono- and polymethylene homologations of copper reagents using (iodomethyl)zinc iodide The Journal of Organic Chemistry. 58: 2694-2713. DOI: 10.1021/Jo00062A010  0.527
1993 Rozema MJ, Eisenberg C, Lütjens H, Ostwald R, Belyk K, Knochell P. Enantioselective preparation of polyfunctional secondary allylic alcohols using functionalized dialkylzincs prepared by a copper(I) catalyzed iodine-zinc exchange reaction. Tetrahedron Letters. 34: 3115-3118. DOI: 10.1016/S0040-4039(00)93393-8  0.411
1993 Knochel P, Brieden W, Rozema MJ, Eisenberg C. A new catalytic asymmetric approach to polyfunctional aldol products mediated by zinc organometallics Tetrahedron Letters. 34: 5881-5884. DOI: 10.1016/S0040-4039(00)73804-4  0.368
1993 Sidduri A, Rozema MJ, Knochel P. Selective mono- and polymethylene homologations of copper reagents using (iodomethyl)zinc iodide Journal of Organic Chemistry. 58: 2694-2713.  0.448
1992 Knochel P, Rozema MJ, Tucker CE, Retherford C, Furlong M, AchyuthaRao S. The chemistry of polyfunctional organozinc and copper reagents Pure and Applied Chemistry. 64: 361-369. DOI: 10.1351/Pac199264030361  0.47
1992 Belyk K, Rozema MJ, Knochel P. Preparation of polyfunctional allenic alcohols by the regioselective addition of functionalized propargylic chromium(III) organometallics to carbonyl compounds The Journal of Organic Chemistry. 57: 4070-4074. DOI: 10.1021/Jo00041A006  0.439
1992 Rozema MJ, Sidduri A, Knochel P. Preparation of functionalized dialkylzinc reagents via an iodine-zinc exchange reaction. Highly enantioselective synthesis of functionalized secondary alcohols The Journal of Organic Chemistry. 57: 1956-1958. DOI: 10.1021/Jo00033A008  0.489
1992 Rozema MJ, Rajagopal D, Tucker CE, Knochel P. Preparation of polyfunctional diorganomercurials and their transmetallation to diorganozincs. Applications to the preparation of optically active secon Journal of Organometallic Chemistry. 438: 11-27. DOI: 10.1016/0022-328X(92)88002-Z  0.442
1992 Rozema MJ, Sidduri A, Knochel P. Preparation of functionalized dialkylzinc reagents via an iodine-zinc exchange reaction. Highly enantioselective synthesis of functionalized secondary alcohols Journal of Organic Chemistry. 57: 1956-1958.  0.365
1992 Belyk K, Rozema MJ, Knochel P. Preparation of polyfunctional allenic alcohols by the regioselective addition of functionalized propargylic chromium(III) organometallics to carbonyl compounds Journal of Organic Chemistry. 57: 4070-4074.  0.337
1991 Knoess HP, Furlong MT, Rozema MJ, Knochel P. Preparation and reactions of zinc and copper organometallics bearing acidic hydrogens Journal of Organic Chemistry. 56: 5974-5978. DOI: 10.1021/Jo00021A003  0.457
1991 Rozema MJ, Knochel P. Selective multiple methylene insertion reactions mediated by iodomethylzine iodide: Mechanistic considerations and synthetic applications Tetrahedron Letters. 32: 1855-1858. DOI: 10.1016/S0040-4039(00)85980-8  0.535
1991 Peter Knoess H, Furlong MT, Rozema MJ, Knochel P. Preparation and reactions of zinc and copper organometallics bearing acidic hydrogens Journal of Organic Chemistry. 56: 5974-5978.  0.362
1989 Knochel P, Chou TS, Chen HG, Yeh MCP, Rozema MJ. Nucleophilic reactivity of zinc and copper carbenoids. Part II Journal of Organic Chemistry. 54: 5202-5204. DOI: 10.1021/Jo00283A006  0.383
1989 Knochel P, Jeong N, Rozema MJ, Yeh MCP. Zinc and copper carbenoids as efficient and selective a1/d1 multicoupling reagents. 1 Journal of the American Chemical Society. 111: 6474-6476. DOI: 10.1021/Ja00198A097  0.379
1989 Knochel P, Chou TS, Chen HG, Yeh MCP, Rozema MJ. Nucleophilic reactivity of zinc and copper carbenoids. 2 Journal of Organic Chemistry. 54: 5202-5204.  0.336
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