| Year |
Citation |
Score |
| 2023 |
Gavin AL, Blane TR, Thinnes TC, Gerlt E, Marshak-Rothstein A, Huang D, Nemazee D. Disease in the Pld4thss/thss Model of Murine Lupus Requires TLR9. Immunohorizons. 7: 577-586. PMID 37555846 DOI: 10.4049/immunohorizons.2300058 |
0.356 |
|
| 2023 |
Hurtado J, Flynn C, Lee JH, Salcedo EC, Cottrell CA, Skog PD, Burton DR, Nemazee D, Schief WR, Landais E, Sok D, Briney B. Efficient isolation of rare B cells using next-generation antigen barcoding. Frontiers in Cellular and Infection Microbiology. 12: 962945. PMID 36968243 DOI: 10.3389/fcimb.2022.962945 |
0.471 |
|
| 2022 |
Okoreeh MK, Kennedy DE, Emmanuel AO, Veselits M, Moshin A, Ladd RH, Erickson S, McLean KC, Madrigal B, Nemazee D, Maienschein-Cline M, Mandal M, Clark MR. Asymmetrical forward and reverse developmental trajectories determine molecular programs of B cell antigen receptor editing. Science Immunology. 7: eabm1664. PMID 35930652 DOI: 10.1126/sciimmunol.abm1664 |
0.569 |
|
| 2022 |
Nahmad AD, Lazzarotto CR, Zelikson N, Kustin T, Tenuta M, Huang D, Reuveni I, Nataf D, Raviv Y, Horovitz-Fried M, Dotan I, Carmi Y, Rosin-Arbesfeld R, Nemazee D, Voss JE, et al. In vivo engineered B cells secrete high titers of broadly neutralizing anti-HIV antibodies in mice. Nature Biotechnology. PMID 35681059 DOI: 10.1038/s41587-022-01328-9 |
0.475 |
|
| 2021 |
Cho H, Gonzales-Wartz KK, Huang D, Yuan M, Peterson M, Liang J, Beutler N, Torres JL, Cong Y, Postnikova E, Bangaru S, Talana CA, Shi W, Yang ES, Zhang Y, ... ... Nemazee D, et al. Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants. Biorxiv : the Preprint Server For Biology. PMID 33821267 DOI: 10.1101/2021.04.01.437942 |
0.347 |
|
| 2020 |
Huang D, Tran JT, Olson A, Vollbrecht T, Tenuta M, Guryleva MV, Fuller RP, Schiffner T, Abadejos JR, Couvrette L, Blane TR, Saye K, Li W, Landais E, Gonzalez-Martin A, ... ... Nemazee D, et al. Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells. Nature Communications. 11: 5850. PMID 33203876 DOI: 10.1038/s41467-020-19650-8 |
0.397 |
|
| 2020 |
Huang D, Abbott RK, Havenar-Daughton C, Skog PD, Al-Kolla R, Groschel B, Blane TR, Menis S, Tran JT, Thinnes TC, Volpi SA, Liguori A, Schiffner T, Villegas SM, Kalyuzhniy O, ... ... Nemazee D, et al. B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models. Proceedings of the National Academy of Sciences of the United States of America. PMID 32873644 DOI: 10.1073/Pnas.2004489117 |
0.565 |
|
| 2020 |
Phillips N, Ke E, Nham A, Seidl M, Freeman B, Abadejos JR, Xiao C, Nemazee D, Ku M, Kirak O. Prediabetes Induced by a Single Autoimmune B Cell Clone. Frontiers in Immunology. 11: 1073. PMID 32625203 DOI: 10.3389/Fimmu.2020.01073 |
0.637 |
|
| 2020 |
Rogers TF, Zhao F, Huang D, Beutler N, Burns A, He WT, Limbo O, Smith C, Song G, Woehl J, Yang L, Abbott RK, Callaghan S, Garcia E, Hurtado J, ... ... Nemazee D, et al. Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model. Science (New York, N.Y.). PMID 32540903 DOI: 10.1126/Science.Abc7520 |
0.329 |
|
| 2020 |
Wec AZ, Wrapp D, Herbert AS, Maurer DP, Haslwanter D, Sakharkar M, Jangra RK, Dieterle ME, Lilov A, Huang D, Tse LV, Johnson NV, Hsieh CL, Wang N, Nett JH, ... ... Nemazee D, et al. Broad neutralization of SARS-related viruses by human monoclonal antibodies. Science (New York, N.Y.). PMID 32540900 DOI: 10.1126/Science.Abc7424 |
0.413 |
|
| 2020 |
Xiao C, Nemazee D, Gonzalez-Martin A. MicroRNA control of B cell tolerance, autoimmunity and cancer. Seminars in Cancer Biology. 64: 102-107. PMID 32522353 DOI: 10.1016/J.Semcancer.2019.04.004 |
0.378 |
|
| 2020 |
Wec AZ, Wrapp D, Herbert AS, Maurer D, Haslwanter D, Sakharkar M, Jangra RK, Dieterle ME, Lilov A, Huang D, Tse LV, Johnson NV, Hsieh CL, Wang N, Nett JH, ... ... Nemazee D, et al. Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein. Biorxiv : the Preprint Server For Biology. PMID 32511337 DOI: 10.1101/2020.05.15.096511 |
0.303 |
|
| 2019 |
Melo M, Porter E, Zhang Y, Silva M, Li N, Dobosh B, Liguori A, Skog P, Landais E, Menis S, Sok D, Nemazee D, Schief WR, Weiss R, Irvine DJ. Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31515132 DOI: 10.1016/J.Ymthe.2019.08.007 |
0.492 |
|
| 2019 |
Bancroft T, DeBuysscher BL, Weidle C, Schwartz A, Wall A, Gray MD, Feng J, Steach HR, Fitzpatrick KS, Gewe MM, Skog PD, Doyle-Cooper C, Ota T, Strong RK, Nemazee D, et al. Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes. The Journal of Experimental Medicine. PMID 31345930 DOI: 10.2210/Pdb6Ol5/Pdb |
0.52 |
|
| 2019 |
Sinha RK, Flynn R, Zaiken M, Paz K, Gavin AL, Nemazee D, Fernández JA, Xu X, Griffin JH, Blazar BR. Activated Protein C Ameliorates Chronic Graft-Versus-Host Disease by PAR1-dependent Biased Cell Signaling on T-cells. Blood. PMID 31243040 DOI: 10.1182/Blood.2019001259 |
0.384 |
|
| 2019 |
Bhullar D, Nemazee D. B Cells Carrying Antigen Receptors Against Microbes as Tools for Vaccine Discovery and Design. Current Topics in Microbiology and Immunology. PMID 30919086 DOI: 10.1007/82_2019_156 |
0.531 |
|
| 2019 |
Voss JE, Gonzalez-Martin A, Andrabi R, Fuller RP, Murrell B, McCoy LE, Porter K, Huang D, Li W, Sok D, Le K, Briney B, Chateau M, Rogers G, Hangartner L, ... ... Nemazee D, et al. Reprogramming the antigen specificity of B cells using genome-editing technologies. Elife. 8. PMID 30648968 DOI: 10.7554/Elife.42995 |
0.593 |
|
| 2018 |
Gavin AL, Huang D, Huber C, Mårtensson A, Tardif V, Skog PD, Blane TR, Thinnes TC, Osborn K, Chong HS, Kargaran F, Kimm P, Zeitjian A, Sielski RL, Briggs M, ... ... Nemazee D, et al. PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing. Nature Immunology. PMID 30111894 DOI: 10.1038/S41590-018-0179-Y |
0.337 |
|
| 2018 |
Voss JE, Gonzalez-Martin A, Andrabi R, Fuller RP, Murrell B, McCoy LE, Porter K, Huang D, Li W, Sok D, Le K, Briney B, Chateau M, Rogers G, Hangartner L, ... ... Nemazee D, et al. Author response: Reprogramming the antigen specificity of B cells using genome-editing technologies Elife. DOI: 10.7554/Elife.42995.033 |
0.484 |
|
| 2017 |
Abbott RK, Lee JH, Menis S, Skog P, Rossi M, Ota T, Kulp DW, Bhullar D, Kalyuzhniy O, Havenar-Daughton C, Schief WR, Nemazee D, Crotty S. Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens. Immunity. PMID 29287996 DOI: 10.1016/J.Immuni.2017.11.023 |
0.607 |
|
| 2017 |
Kolenbrander A, Grewe B, Nemazee D, Überla K, Temchura V. Generation of T-follicular helper cells in vitro: requirement for BCR cross-linking and cognate B- and T-cell interaction. Immunology. PMID 28881401 DOI: 10.1111/Imm.12834 |
0.571 |
|
| 2017 |
Medina-Ramírez M, Garces F, Escolano A, Skog P, de Taeye SW, Del Moral-Sanchez I, McGuire AT, Yasmeen A, Behrens AJ, Ozorowski G, van den Kerkhof TLGM, Freund NT, Dosenovic P, Hua Y, Gitlin AD, ... ... Nemazee D, et al. Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. The Journal of Experimental Medicine. PMID 28847869 DOI: 10.1084/Jem.20161160 |
0.45 |
|
| 2017 |
Nemazee D. Mechanisms of central tolerance for B cells. Nature Reviews. Immunology. PMID 28368006 DOI: 10.1038/Nri.2017.19 |
0.632 |
|
| 2017 |
Martinic MM, Caminschi I, O'Keeffe M, Thinnes TC, Grumont R, Gerondakis S, McKay DB, Nemazee D, Gavin AL. The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8(+) Thymocyte Selection. Journal of Immunology (Baltimore, Md. : 1950). PMID 28202617 DOI: 10.4049/Jimmunol.1601462 |
0.436 |
|
| 2016 |
Briney B, Sok D, Jardine JG, Kulp DW, Skog P, Menis S, Jacak R, Kalyuzhniy O, de Val N, Sesterhenn F, Le KM, Ramos A, Jones M, Saye-Francisco KL, Blane TR, ... ... Nemazee D, et al. Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies. Cell. 166: 1459-1470.e11. PMID 27610570 DOI: 10.1016/J.Cell.2016.08.005 |
0.373 |
|
| 2016 |
Lai M, Gonzalez-Martin A, Cooper AB, Oda H, Jin HY, Shepherd J, He L, Zhu J, Nemazee D, Xiao C. Regulation of B-cell development and tolerance by different members of the miR-17∼92 family microRNAs. Nature Communications. 7: 12207. PMID 27481093 DOI: 10.1038/Ncomms12207 |
0.475 |
|
| 2016 |
He L, de Val N, Morris CD, Vora N, Thinnes TC, Kong L, Azadnia P, Sok D, Zhou B, Burton DR, Wilson IA, Nemazee D, Ward AB, Zhu J. Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles. Nature Communications. 7: 12041. PMID 27349934 DOI: 10.1038/Ncomms12041 |
0.31 |
|
| 2016 |
Ingale J, Stano A, Guenaga J, Sharma SK, Nemazee D, Zwick MB, Wyatt RT. High-Density Array of Well-Ordered HIV-1 Spikes on Synthetic Liposomal Nanoparticles Efficiently Activate B Cells. Cell Reports. PMID 27210756 DOI: 10.1016/J.Celrep.2016.04.078 |
0.462 |
|
| 2016 |
Gonzalez-Martin A, Adams BD, Lai M, Shepherd J, Salvador-Bernaldez M, Salvador JM, Lu J, Nemazee D, Xiao C. The microRNA miR-148a functions as a critical regulator of B cell tolerance and autoimmunity. Nature Immunology. PMID 26901150 DOI: 10.1038/Ni.3385 |
0.489 |
|
| 2015 |
Lang J, Ota T, Kelly M, Strauch P, Freed BM, Torres RM, Nemazee D, Pelanda R. Receptor editing and genetic variability in human autoreactive B cells. The Journal of Experimental Medicine. PMID 26694971 DOI: 10.1084/Jem.20151039 |
0.585 |
|
| 2015 |
Jardine JG, Ota T, Sok D, Pauthner M, Kulp DW, Kalyuzhniy O, Skog PD, Thinnes TC, Bhullar D, Briney B, Menis S, Jones M, Kubitz M, Spencer S, Adachi Y, ... ... Nemazee D, et al. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen. Science (New York, N.Y.). PMID 26089355 DOI: 10.1126/Science.Aac5894 |
0.392 |
|
| 2013 |
Doyle-Cooper C, Hudson KE, Cooper AB, Ota T, Skog P, Dawson PE, Zwick MB, Schief WR, Burton DR, Nemazee D. Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10. Journal of Immunology (Baltimore, Md. : 1950). 191: 3186-91. PMID 23940276 DOI: 10.4049/Jimmunol.1301285 |
0.54 |
|
| 2013 |
Ota T, Doyle-Cooper C, Cooper AB, Doores KJ, Aoki-Ota M, Le K, Schief WR, Wyatt RT, Burton DR, Nemazee D. B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates. Journal of Immunology (Baltimore, Md. : 1950). 191: 3179-85. PMID 23940273 DOI: 10.4049/Jimmunol.1301283 |
0.538 |
|
| 2013 |
Jardine J, Julien JP, Menis S, Ota T, Kalyuzhniy O, McGuire A, Sok D, Huang PS, MacPherson S, Jones M, Nieusma T, Mathison J, Baker D, Ward AB, Burton DR, ... ... Nemazee D, et al. Rational HIV immunogen design to target specific germline B cell receptors. Science (New York, N.Y.). 340: 711-6. PMID 23539181 DOI: 10.1126/Science.1234150 |
0.379 |
|
| 2013 |
Doores KJ, Huber M, Le KM, Wang SK, Doyle-Cooper C, Cooper A, Pantophlet R, Wong CH, Nemazee D, Burton DR. 2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies. Journal of Virology. 87: 2234-41. PMID 23221565 DOI: 10.1128/Jvi.02820-12 |
0.431 |
|
| 2012 |
Ota T, Doyle-Cooper C, Cooper AB, Huber M, Falkowska E, Doores KJ, Hangartner L, Le K, Sok D, Jardine J, Lifson J, Wu X, Mascola JR, Poignard P, Binley JM, ... ... Nemazee D, et al. Anti-HIV B Cell lines as candidate vaccine biosensors. Journal of Immunology (Baltimore, Md. : 1950). 189: 4816-24. PMID 23066156 DOI: 10.4049/Jimmunol.1202165 |
0.482 |
|
| 2012 |
Aoki-Ota M, Torkamani A, Ota T, Schork N, Nemazee D. Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing. Journal of Immunology (Baltimore, Md. : 1950). 188: 2305-15. PMID 22287713 DOI: 10.4049/Jimmunol.1103484 |
0.502 |
|
| 2012 |
Jardine J, Kalyuzhniy O, Ota T, McGuire A, Menis S, Julien J, Falkowska E, MacPherson S, Jones M, Burton, Wilson I, Stamatatos L, Nemazee D, Schief W. Rational immunogen design to target specific germline B cell receptors. Retrovirology. 9: 1-1. DOI: 10.1186/1742-4690-9-S2-O71 |
0.544 |
|
| 2012 |
Nemazee D, Doyle-Cooper C, Ota T, Cooper A, Huber M, Falkowska E, Doores K, Hangartner L, Le K, Sok D, Jardine J, Lifson J, Wu X, Mascola J, Poignard P, et al. Engineered mice and B cell lines expressing broadly neutralizing antibodies and their unmutated precursors: tools for HIV vaccinology Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-O41 |
0.623 |
|
| 2011 |
Duong BH, Ota T, Aoki-Ota M, Cooper AB, Ait-Azzouzene D, Vela JL, Gavin AL, Nemazee D. Negative selection by IgM superantigen defines a B cell central tolerance compartment and reveals mutations allowing escape. Journal of Immunology (Baltimore, Md. : 1950). 187: 5596-605. PMID 22043016 DOI: 10.4049/Jimmunol.1102479 |
0.836 |
|
| 2011 |
Siggs OM, Arnold CN, Huber C, Pirie E, Xia Y, Lin P, Nemazee D, Beutler B. The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow. Nature Immunology. 12: 434-40. PMID 21423172 DOI: 10.1038/Ni.2012 |
0.455 |
|
| 2011 |
Ota T, Ota M, Duong BH, Gavin AL, Nemazee D. Liver-expressed Igkappa superantigen induces tolerance of polyclonal B cells by clonal deletion not kappa to lambda receptor editing. The Journal of Experimental Medicine. 208: 617-29. PMID 21357741 DOI: 10.1084/Jem.20102265 |
0.845 |
|
| 2011 |
Tiegs SL, Russell DM, Nemazee D. Receptor editing in self-reactive bone marrow B cells. The Journal of Experimental Medicine. 1993. 177: 1009-1020. Journal of Immunology (Baltimore, Md. : 1950). 186: 1313-24. PMID 21248269 |
0.376 |
|
| 2010 |
Ota M, Duong BH, Torkamani A, Doyle CM, Gavin AL, Ota T, Nemazee D. Regulation of the B cell receptor repertoire and self-reactivity by BAFF. Journal of Immunology (Baltimore, Md. : 1950). 185: 4128-36. PMID 20817867 DOI: 10.4049/Jimmunol.1002176 |
0.835 |
|
| 2010 |
Aït-Azzouzene D, Kono DH, Gonzalez-Quintial R, McHeyzer-Williams LJ, Lim M, Wickramarachchi D, Gerdes T, Gavin AL, Skog P, McHeyzer-Williams MG, Nemazee D, Theofilopoulos AN. Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice. Journal of Immunology (Baltimore, Md. : 1950). 185: 1015-27. PMID 20554953 DOI: 10.4049/Jimmunol.1000698 |
0.614 |
|
| 2010 |
Duong BH, Ota T, Aït-Azzouzene D, Aoki-Ota M, Vela JL, Huber C, Walsh K, Gavin AL, Nemazee D. Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen. Journal of Immunology (Baltimore, Md. : 1950). 184: 4143-58. PMID 20231687 DOI: 10.4049/Jimmunol.0903564 |
0.843 |
|
| 2010 |
Siggs OM, Berger M, Krebs P, Arnold CN, Eidenschenk C, Huber C, Pirie E, Smart NG, Khovananth K, Xia Y, McInerney G, Karlsson Hedestam GB, Nemazee D, Beutler B. A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha. Proceedings of the National Academy of Sciences of the United States of America. 107: 3046-51. PMID 20133626 DOI: 10.1073/Pnas.0915098107 |
0.4 |
|
| 2010 |
Duong BH, Tian H, Ota T, Completo G, Han S, Vela JL, Ota M, Kubitz M, Bovin N, Paulson JC, Paulson J, Nemazee D. Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo. The Journal of Experimental Medicine. 207: 173-87. PMID 20038598 DOI: 10.1084/Jem.20091873 |
0.817 |
|
| 2010 |
Duong BH, Tian H, Ota T, Completo G, Han S, Vela JL, Ota M, Kubitz M, Bovin N, Paulson JC, Nemazee D. Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo (Journal of Experimental Medicine (2010), 207, 1, (173-177)) Journal of Experimental Medicine. 207. |
0.768 |
|
| 2009 |
Beck K, Peak MM, Ota T, Nemazee D, Murre C. Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci. The Journal of Experimental Medicine. 206: 2271-84. PMID 19752184 DOI: 10.1084/Jem.20090756 |
0.484 |
|
| 2009 |
Ota T, Aoki-Ota M, Duong BH, Nemazee D. Suppression of IgE B cells and IgE binding to Fc(epsilon)RI by gene therapy with single-chain anti-IgE. Journal of Immunology (Baltimore, Md. : 1950). 182: 8110-7. PMID 19494337 DOI: 10.4049/Jimmunol.0900300 |
0.803 |
|
| 2008 |
Huber C, Mårtensson A, Bokoch GM, Nemazee D, Gavin AL. FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles. The Journal of Biological Chemistry. 283: 34002-12. PMID 18838382 DOI: 10.1074/Jbc.M803957200 |
0.582 |
|
| 2008 |
Vela JL, Aït-Azzouzene D, Duong BH, Ota T, Nemazee D. Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production. Immunity. 28: 161-70. PMID 18261939 DOI: 10.1016/J.Immuni.2007.12.011 |
0.793 |
|
| 2007 |
Lamoureux JL, Watson LC, Cherrier M, Skog P, Nemazee D, Feeney AJ. Reduced receptor editing in lupus-prone MRL/lpr mice. The Journal of Experimental Medicine. 204: 2853-64. PMID 17967905 DOI: 10.1084/Jem.20071268 |
0.621 |
|
| 2007 |
Verkoczy L, Duong B, Skog P, Aït-Azzouzene D, Puri K, Vela JL, Nemazee D. Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection. Journal of Immunology (Baltimore, Md. : 1950). 178: 6332-41. PMID 17475862 DOI: 10.4049/Jimmunol.178.10.6332 |
0.823 |
|
| 2007 |
Wucherpfennig KW, Allen PM, Celada F, Cohen IR, De Boer R, Garcia KC, Goldstein B, Greenspan R, Hafler D, Hodgkin P, Huseby ES, Krakauer DC, Nemazee D, Perelson AS, Pinilla C, et al. Polyspecificity of T cell and B cell receptor recognition. Seminars in Immunology. 19: 216-24. PMID 17398114 DOI: 10.1016/J.Smim.2007.02.012 |
0.54 |
|
| 2007 |
Vela JL, Nemazee D. Role of RS/kappaDE in B cell receptor editing. Advances in Experimental Medicine and Biology. 596: 169-72. PMID 17338186 DOI: 10.1007/0-387-46530-8_16 |
0.463 |
|
| 2006 |
Gavin AL, Hoebe K, Duong B, Ota T, Martin C, Beutler B, Nemazee D. Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling. Science (New York, N.Y.). 314: 1936-8. PMID 17185603 DOI: 10.1126/Science.1135299 |
0.733 |
|
| 2006 |
Nemazee D. Receptor editing in lymphocyte development and central tolerance. Nature Reviews. Immunology. 6: 728-40. PMID 16998507 DOI: 10.1038/Nri1939 |
0.5 |
|
| 2006 |
Watson LC, Moffatt-Blue CS, McDonald RZ, Kompfner E, Ait-Azzouzene D, Nemazee D, Theofilopoulos AN, Kono DH, Feeney AJ. Paucity of V-D-D-J rearrangements and VH replacement events in lupus prone and nonautoimmune TdT-/- and TdT+/+ mice. Journal of Immunology (Baltimore, Md. : 1950). 177: 1120-8. PMID 16818769 DOI: 10.4049/Jimmunol.177.2.1120 |
0.387 |
|
| 2006 |
Nemazee D, Gavin A, Hoebe K, Beutler B. Immunology: Toll-like receptors and antibody responses. Nature. 441: E4; discussion E4. PMID 16710369 DOI: 10.1038/Nature04875 |
0.444 |
|
| 2006 |
Aït-Azzouzene D, Gavin AL, Skog P, Duong B, Nemazee D. Effect of cell:cell competition and BAFF expression on peripheral B cell tolerance and B-1 cell survival in transgenic mice expressing a low level of Igkappa-reactive macroself antigen. European Journal of Immunology. 36: 985-96. PMID 16511898 DOI: 10.1002/Eji.200535581 |
0.847 |
|
| 2006 |
Aït-Azzouzene D, Verkoczy L, Duong B, Skog P, Gavin AL, Nemazee D. Split tolerance in peripheral B cell subsets in mice expressing a low level of Igkappa-reactive ligand. Journal of Immunology (Baltimore, Md. : 1950). 176: 939-48. PMID 16393979 DOI: 10.4049/Jimmunol.176.2.939 |
0.846 |
|
| 2005 |
Gavin AL, Duong B, Skog P, Aït-Azzouzene D, Greaves DR, Scott ML, Nemazee D. deltaBAFF, a splice isoform of BAFF, opposes full-length BAFF activity in vivo in transgenic mouse models. Journal of Immunology (Baltimore, Md. : 1950). 175: 319-28. PMID 15972664 DOI: 10.4049/Jimmunol.175.1.319 |
0.836 |
|
| 2005 |
Peters B, Sidney J, Bourne P, Bui HH, Buus S, Doh G, Fleri W, Kronenberg M, Kubo R, Lund O, Nemazee D, Ponomarenko JV, Sathiamurthy M, Schoenberger SP, Stewart S, et al. The design and implementation of the immune epitope database and analysis resource. Immunogenetics. 57: 326-36. PMID 15895191 DOI: 10.1007/S00251-005-0803-5 |
0.311 |
|
| 2005 |
Verkoczy L, Aït-Azzouzene D, Skog P, Märtensson A, Lang J, Duong B, Nemazee D. A role for nuclear factor kappa B/rel transcription factors in the regulation of the recombinase activator genes. Immunity. 22: 519-31. PMID 15845455 DOI: 10.1016/J.Immuni.2005.03.006 |
0.806 |
|
| 2005 |
Peters B, Sidney J, Bourne P, Bui HH, Buus S, Doh G, Fleri W, Kronenberg M, Kubo R, Lund O, Nemazee D, Ponomarenko JV, Sathiamurthy M, Schoenberger S, Stewart S, et al. The immune epitope database and analysis resource: from vision to blueprint. Plos Biology. 3: e91. PMID 15760272 DOI: 10.1371/Journal.Pbio.0030091 |
0.396 |
|
| 2005 |
Ait-Azzouzene D, Verkoczy L, Peters J, Gavin A, Skog P, Vela JL, Nemazee D. An immunoglobulin C kappa-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system. The Journal of Experimental Medicine. 201: 817-28. PMID 15738053 DOI: 10.1084/Jem.20041854 |
0.559 |
|
| 2004 |
Verkoczy LK, Mårtensson AS, Nemazee D. The scope of receptor editing and its association with autoimmunity. Current Opinion in Immunology. 16: 808-14. PMID 15511677 DOI: 10.1016/J.Coi.2004.09.017 |
0.49 |
|
| 2004 |
Gavin A, Aït-Azzouzene D, Mårtensson A, Duong B, Verkoczy L, Vela JL, Skog JL, Skog P, Nemazee D. Peripheral B lymphocyte tolerance. The Keio Journal of Medicine. 53: 151-8. PMID 15477728 DOI: 10.2302/Kjm.53.151 |
0.846 |
|
| 2004 |
Quong MW, Martensson A, Langerak AW, Rivera RR, Nemazee D, Murre C. Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2A. The Journal of Experimental Medicine. 199: 1101-12. PMID 15078898 DOI: 10.1084/Jem.20031180 |
0.668 |
|
| 2004 |
Silveira PA, Dombrowsky J, Johnson E, Chapman HD, Nemazee D, Serreze DV. B cell selection defects underlie the development of diabetogenic APCs in nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 172: 5086-94. PMID 15067092 DOI: 10.4049/Jimmunol.172.8.5086 |
0.626 |
|
| 2004 |
Aït-Azzouzene D, Skog P, Retter M, Kouskoff V, Hertz M, Lang J, Kench J, Chumley M, Melamed D, Sudaria J, Gavin A, Martensson A, Verkoczy L, Duong B, Vela J, ... Nemazee D, et al. Tolerance-induced receptor selection: scope, sensitivity, locus specificity, and relationship to lymphocyte-positive selection. Immunological Reviews. 197: 219-30. PMID 14962198 DOI: 10.1111/J.0105-2896.2004.0106.X |
0.838 |
|
| 2003 |
Gavin AL, Aït-Azzouzene D, Ware CF, Nemazee D. DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF. The Journal of Biological Chemistry. 278: 38220-8. PMID 12867412 DOI: 10.1074/jbc.M306852200 |
0.478 |
|
| 2003 |
Pape KA, Kouskoff V, Nemazee D, Tang HL, Cyster JG, Tze LE, Hippen KL, Behrens TW, Jenkins MK. Visualization of the genesis and fate of isotype-switched B cells during a primary immune response. The Journal of Experimental Medicine. 197: 1677-87. PMID 12796466 DOI: 10.1084/Jem.20012065 |
0.637 |
|
| 2003 |
Nemazee D, Hogquist KA. Antigen receptor selection by editing or downregulation of V(D)J recombination. Current Opinion in Immunology. 15: 182-9. PMID 12633668 DOI: 10.1016/S0952-7915(03)00008-6 |
0.578 |
|
| 2003 |
Nemazee D, Gavin A. Do B cells take advantage of 'missing self' recognition? Current Directions in Autoimmunity. 6: 245-64. PMID 12408056 DOI: 10.1159/000066852 |
0.518 |
|
| 2002 |
Nemazee D, Mårtensson A, Verkoczy L. Haplotype exclusion and receptor editing: irreconcilable differences? Seminars in Immunology. 14: 191-8; discussion 22. PMID 12160646 DOI: 10.1016/S1044-5323(02)00042-8 |
0.457 |
|
| 2001 |
Kouskoff V, Nemazee D. Role of receptor editing and revision in shaping the B and T lymphocyte repertoire. Life Sciences. 69: 1105-13. PMID 11508343 DOI: 10.1016/S0024-3205(01)01219-X |
0.579 |
|
| 2001 |
Casellas R, Shih TA, Kleinewietfeld M, Rakonjac J, Nemazee D, Rajewsky K, Nussenzweig MC. Contribution of receptor editing to the antibody repertoire. Science (New York, N.Y.). 291: 1541-4. PMID 11222858 DOI: 10.1126/Science.1056600 |
0.548 |
|
| 2000 |
Buhl AM, Nemazee D, Cambier JC, Rickert R, Hertz M. B-cell antigen receptor competence regulates B-lymphocyte selection and survival. Immunological Reviews. 176: 141-53. PMID 11043774 |
0.616 |
|
| 2000 |
Melamed D, Miri E, Leider N, Nemazee D. Unexpected autoantibody production in membrane Ig-mu-deficient/lpr mice. Journal of Immunology (Baltimore, Md. : 1950). 165: 4353-8. PMID 11035071 DOI: 10.4049/Jimmunol.165.8.4353 |
0.662 |
|
| 2000 |
Nemazee D. Role of B cell antigen receptor in regulation of V(D)J recombination and cell survival. Immunologic Research. 21: 259-63. PMID 10852126 DOI: 10.1385/Ir:21:2-3:259 |
0.647 |
|
| 2000 |
Nemazee D, Weigert M. Revising B cell receptors. The Journal of Experimental Medicine. 191: 1813-7. PMID 10839798 DOI: 10.1084/Jem.191.11.1813 |
0.633 |
|
| 2000 |
Nemazee D. Receptor selection in B and T lymphocytes. Annual Review of Immunology. 18: 19-51. PMID 10837051 DOI: 10.1146/Annurev.Immunol.18.1.19 |
0.56 |
|
| 2000 |
Kouskoff V, Lacaud G, Pape K, Retter M, Nemazee D. B cell receptor expression level determines the fate of developing B lymphocytes: receptor editing versus selection. Proceedings of the National Academy of Sciences of the United States of America. 97: 7435-9. PMID 10829082 DOI: 10.1073/Pnas.130182597 |
0.562 |
|
| 2000 |
Chumley MJ, Dal Porto JM, Kawaguchi S, Cambier JC, Nemazee D, Hardy RR. A VH11V kappa 9 B cell antigen receptor drives generation of CD5+ B cells both in vivo and in vitro. Journal of Immunology (Baltimore, Md. : 1950). 164: 4586-93. PMID 10779761 DOI: 10.4049/Jimmunol.164.9.4586 |
0.841 |
|
| 2000 |
Kouskoff V, Lacaud G, Nemazee D. T cell-independent rescue of B lymphocytes from peripheral immune tolerance. Science (New York, N.Y.). 287: 2501-3. PMID 10741972 DOI: 10.1126/Science.287.5462.2501 |
0.519 |
|
| 2000 |
Lang J, Nemazee D. B cell clonal elimination induced by membrane-bound self-antigen may require repeated antigen encounter or cell competition. European Journal of Immunology. 30: 689-96. PMID 10671228 DOI: 10.1002/1521-4141(200002)30:2<689::Aid-Immu689>3.0.Co;2-I |
0.648 |
|
| 2000 |
Nemazee D. Receptor editing in B cells. Advances in Immunology. 74: 89-126. PMID 10605605 DOI: 10.1016/S0065-2776(08)60909-8 |
0.641 |
|
| 2000 |
Nemazee D, Kouskoff V, Hertz M, Lang J, Melamed D, Pape K, Retter M. B-cell-receptor-dependent positive and negative selection in immature B cells. Current Topics in Microbiology and Immunology. 245: 57-71. PMID 10533318 DOI: 10.1007/978-3-642-59641-4_3 |
0.62 |
|
| 1999 |
Melamed D, Nemazee D. Immunoglobulin transgenes in B lymphocyte development, tolerance, and autoimmunity. Current Directions in Autoimmunity. 1: 1-30. PMID 11791439 DOI: 10.1159/000060494 |
0.592 |
|
| 1999 |
Retter MW, Nemazee D. Receptor editing: genetic reprogramming of autoreactive lymphocytes. Cell Biochemistry and Biophysics. 31: 81-8. PMID 10505669 DOI: 10.1007/Bf02738156 |
0.588 |
|
| 1999 |
Benschop RJ, Melamed D, Nemazee D, Cambier JC. Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells. The Journal of Experimental Medicine. 190: 749-56. PMID 10499913 DOI: 10.1084/Jem.190.6.749 |
0.638 |
|
| 1999 |
Kench JA, Russell DM, Fadok VA, Young SK, Worthen GS, Jones-Carson J, Henson JE, Henson PM, Nemazee D. Aberrant wound healing and TGF-beta production in the autoimmune-prone MRL/+ mouse. Clinical Immunology (Orlando, Fla.). 92: 300-10. PMID 10479535 DOI: 10.1006/Clim.1999.4754 |
0.375 |
|
| 1998 |
Kouskoff V, Famiglietti S, Lacaud G, Lang P, Rider JE, Kay BK, Cambier JC, Nemazee D. Antigens varying in affinity for the B cell receptor induce differential B lymphocyte responses. The Journal of Experimental Medicine. 188: 1453-64. PMID 9782122 DOI: 10.1084/Jem.188.8.1453 |
0.63 |
|
| 1998 |
Retter MW, Nemazee D. Receptor editing occurs frequently during normal B cell development. The Journal of Experimental Medicine. 188: 1231-8. PMID 9763602 DOI: 10.1084/Jem.188.7.1231 |
0.573 |
|
| 1998 |
Aït-Azzouzene D, Gendron MC, Houdayer M, Langkopf A, Bürki K, Nemazee D, Kanellopoulos-Langevin C. Maternal B lymphocytes specific for paternal histocompatibility antigens are partially deleted during pregnancy. Journal of Immunology (Baltimore, Md. : 1950). 161: 2677-83. PMID 9743323 |
0.541 |
|
| 1998 |
Kench JA, Russell DM, Nemazee D. Efficient peripheral clonal elimination of B lymphocytes in MRL/lpr mice bearing autoantibody transgenes. The Journal of Experimental Medicine. 188: 909-17. PMID 9730892 DOI: 10.1084/Jem.188.5.909 |
0.578 |
|
| 1998 |
Hertz M, Kouskoff V, Nakamura T, Nemazee D. V(D)J recombinase induction in splenic B lymphocytes is inhibited by antigen-receptor signalling. Nature. 394: 292-5. PMID 9685161 DOI: 10.1038/28419 |
0.588 |
|
| 1998 |
Hertz M, Nemazee D. Receptor editing and commitment in B lymphocytes. Current Opinion in Immunology. 10: 208-13. PMID 9602310 DOI: 10.1016/S0952-7915(98)80250-1 |
0.664 |
|
| 1998 |
Nemazee D. Theoretical limits to massive receptor editing in immature B cells. Current Topics in Microbiology and Immunology. 229: 163-71. PMID 9479854 DOI: 10.1007/978-3-642-71984-4_12 |
0.421 |
|
| 1998 |
Melamed D, Benschop RJ, Cambier JC, Nemazee D. Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection. Cell. 92: 173-82. PMID 9458042 DOI: 10.1016/S0092-8674(00)80912-5 |
0.616 |
|
| 1998 |
Aït-Azzouzene D, Gendron MC, Houdayer M, Langkopf A, Bürki K, Nemazee D, Kanellopoulos-Langevin C. Maternal B lymphocytes specific for paternal histo-compatibility antigens are partially deleted during pregnancy Faseb Journal. 12: A883. |
0.516 |
|
| 1997 |
Foster MH, Liu Q, Chen H, Nemazee D, Cooperstone BG. Anti-laminin reactivity and glomerular immune deposition by in vitro recombinant antibodies. Autoimmunity. 26: 231-43. PMID 9543184 DOI: 10.3109/08916939709008029 |
0.411 |
|
| 1997 |
Pelanda R, Schwers S, Sonoda E, Torres RM, Nemazee D, Rajewsky K. Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification. Immunity. 7: 765-75. PMID 9430222 DOI: 10.1016/S1074-7613(00)80395-7 |
0.672 |
|
| 1997 |
Lang J, Arnold B, Hammerling G, Harris AW, Korsmeyer S, Russell D, Strasser A, Nemazee D. Enforced Bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral B cells in an antigen dose-dependent manner and promotes receptor editing in autoreactive, immature B cells. The Journal of Experimental Medicine. 186: 1513-22. PMID 9348309 DOI: 10.1084/Jem.186.9.1513 |
0.693 |
|
| 1997 |
Papavasiliou F, Casellas R, Suh H, Qin XF, Besmer E, Pelanda R, Nemazee D, Rajewsky K, Nussenzweig MC. V(D)J recombination in mature B cells: a mechanism for altering antibody responses. Science (New York, N.Y.). 278: 298-301. PMID 9323210 DOI: 10.1126/Science.278.5336.298 |
0.537 |
|
| 1997 |
Melamed D, Nemazee D. Self-antigen does not accelerate immature B cell apoptosis, but stimulates receptor editing as a consequence of developmental arrest. Proceedings of the National Academy of Sciences of the United States of America. 94: 9267-72. PMID 9256471 DOI: 10.1073/Pnas.94.17.9267 |
0.599 |
|
| 1997 |
Melamed D, Kench JA, Grabstein K, Rolink A, Nemazee D. A functional B cell receptor transgene allows efficient IL-7-independent maturation of B cell precursors. Journal of Immunology (Baltimore, Md. : 1950). 159: 1233-9. PMID 9233618 |
0.496 |
|
| 1997 |
Hertz M, Nemazee D. BCR ligation induces receptor editing in IgM+IgD- bone marrow B cells in vitro. Immunity. 6: 429-36. PMID 9133422 DOI: 10.1016/S1074-7613(00)80286-1 |
0.594 |
|
| 1996 |
Lang J, Jackson M, Teyton L, Brunmark A, Kane K, Nemazee D. B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen. The Journal of Experimental Medicine. 184: 1685-97. PMID 8920858 DOI: 10.1084/Jem.184.5.1685 |
0.645 |
|
| 1996 |
Nemazee D. Can receptor editing play an important role in normal B-cell development? Journal of Autoimmunity. 9: 259-61. PMID 8738971 DOI: 10.1006/Jaut.1996.0032 |
0.593 |
|
| 1996 |
Rubio CF, Kench J, Russell DM, Yawger R, Nemazee D. Analysis of central B cell tolerance in autoimmune-prone MRL/lpr mice bearing autoantibody transgenes. Journal of Immunology (Baltimore, Md. : 1950). 157: 65-71. PMID 8683157 |
0.496 |
|
| 1996 |
Nemazee D. Antigen receptor 'capacity' and the sensitivity of self-tolerance. Immunology Today. 17: 25-9. PMID 8652047 DOI: 10.1016/0167-5699(96)80565-2 |
0.686 |
|
| 1995 |
Nemazee D. Does immunological tolerance explain the waste in the B-lymphocyte immune system? Experiment and theory. Annals of the New York Academy of Sciences. 764: 397-401. PMID 7486554 |
0.336 |
|
| 1994 |
Spanopoulou E, Roman CA, Corcoran LM, Schlissel MS, Silver DP, Nemazee D, Nussenzweig MC, Shinton SA, Hardy RR, Baltimore D. Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice. Genes & Development. 8: 1030-42. PMID 7926785 DOI: 10.1101/Gad.8.9.1030 |
0.681 |
|
| 1993 |
Tiegs SL, Russell DM, Nemazee D. Receptor editing in self-reactive bone marrow B cells. The Journal of Experimental Medicine. 177: 1009-20. PMID 8459201 DOI: 10.1084/Jem.177.4.1009 |
0.617 |
|
| 1993 |
Nemazee D. Promotion and prevention of autoimmunity by B lymphocytes. Current Opinion in Immunology. 5: 866-72. PMID 8297518 DOI: 10.1016/0952-7915(93)90098-D |
0.622 |
|
| 1992 |
Nemazee D. Mechanisms and meaning of B-lymphocyte tolerance. Research in Immunology. 143: 272-5. PMID 1631404 DOI: 10.1016/S0923-2494(92)80118-5 |
0.441 |
|
| 1992 |
Cuende E, Kroemer G, Alonso JM, Nemazee D, Martínez C, Alés-Martínez JE. Inability of IL-2 and IL-10 to counteract B cell clonal deletion. Cellular Immunology. 142: 94-102. PMID 1586962 DOI: 10.1016/0008-8749(92)90271-P |
0.561 |
|
| 1991 |
Russell DM, Dembić Z, Morahan G, Miller JF, Bürki K, Nemazee D. Peripheral deletion of self-reactive B cells. Nature. 354: 308-11. PMID 1956380 DOI: 10.1038/354308A0 |
0.643 |
|
| 1991 |
Nemazee D, Russell D, Arnold B, Haemmerling G, Allison J, Miller JF, Morahan G, Buerki K. Clonal deletion of autospecific B lymphocytes. Immunological Reviews. 122: 117-32. PMID 1937539 DOI: 10.1111/J.1600-065X.1991.Tb00600.X |
0.678 |
|
| 1991 |
Nemazee D, Guiet C, Buerki K, Marshak-Rothstein A. B lymphocytes from the autoimmune-prone mouse strain MLR/lpr manifest an intrinsic defect in tetraparental MRL/lpr in equilibrium DBA/2 chimeras. Journal of Immunology (Baltimore, Md. : 1950). 147: 2536-9. PMID 1918976 |
0.438 |
|
| 1991 |
Carbone A, Harbeck R, Dallas A, Nemazee D, Finkel T, O'Brien R, Kubo R, Born W. Alpha beta T-lymphocyte depleted mice, a model for gamma delta T-lymphocyte functional studies. Immunological Reviews. 120: 35-50. PMID 1830862 DOI: 10.1111/J.1600-065X.1991.Tb00586.X |
0.375 |
|
| 1989 |
Nemazee DA, Bürki K. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes. Nature. 337: 562-6. PMID 2783762 DOI: 10.1038/337562a0 |
0.517 |
|
| 1989 |
Nemazee D, Buerki K. Clonal deletion of autoreactive B lymphocytes in bone marrow chimeras. Proceedings of the National Academy of Sciences of the United States of America. 86: 8039-43. PMID 2682636 DOI: 10.1073/Pnas.86.20.8039 |
0.585 |
|
| 1987 |
Rammensee HG, Julius MH, Nemazee D, Langhorne J, Lamers R, Köhler G. Targeting cytotoxic T cells to antigen-specific B lymphocytes. European Journal of Immunology. 17: 433-6. PMID 3494614 DOI: 10.1002/Eji.1830170322 |
0.593 |
|
| 1987 |
Shlomchik M, Nemazee D, van Snick J, Weigert M. Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). II. Comparison of hybridomas derived by lipopolysaccharide stimulation and secondary protein immunization. The Journal of Experimental Medicine. 165: 970-87. PMID 3494096 DOI: 10.1084/Jem.165.4.970 |
0.491 |
|
| 1986 |
Shlomchik MJ, Nemazee DA, Sato VL, Van Snick J, Carson DA, Weigert MG. Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cells. The Journal of Experimental Medicine. 164: 407-27. PMID 3088205 DOI: 10.1084/Jem.164.2.407 |
0.375 |
|
| 1985 |
Nemazee DA, Studer S, Steinmetz M, Dembić Z, Kiefer M. The lymphoproliferating cells of MRL-lpr/lpr mice are a polyclonal population that bear the T lymphocyte receptor for antigen. European Journal of Immunology. 15: 760-4. PMID 4029256 DOI: 10.1002/eji.1830150804 |
0.409 |
|
| 1985 |
Nemazee DA. Immune complexes can trigger specific, T cell-dependent, autoanti-IgG antibody production in mice. The Journal of Experimental Medicine. 161: 242-56. PMID 2578542 |
0.329 |
|
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