Judes Poirier - Publications

Affiliations: 
McGill University, Montreal, QC, Canada 

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Quesnel MJ, Labonté A, Picard C, Zetterberg H, Blennow K, Brinkmalm A, Villeneuve S, Poirier J. Insulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains. Brain : a Journal of Neurology. PMID 37992295 DOI: 10.1093/brain/awad398  0.342
2023 Yakoub Y, Ashton NJ, Strikwerda-Brown C, Montoliu-Gaya L, Karikari TK, Kac PR, Gonzalez-Ortiz F, Gallego-Rudolf J, Meyer PF, St-Onge F, Schöll M, Soucy JP, Breitner JCS, Zetterberg H, Blennow K, ... Poirier J, et al. Longitudinal blood biomarker trajectories in preclinical Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37294682 DOI: 10.1002/alz.13318  0.319
2022 Savignac C, Villeneuve S, Badhwar A, Saltoun K, Shafighi K, Zajner C, Sharma V, Gagliano Taliun SA, Farhan S, Poirier J, Bzdok D. APOE alleles are associated with sex-specific structural differences in brain regions affected in Alzheimer's disease and related dementia. Plos Biology. 20: e3001863. PMID 36512526 DOI: 10.1371/journal.pbio.3001863  0.337
2022 Strikwerda-Brown C, Hobbs DA, Gonneaud J, St-Onge F, Binette AP, Ozlen H, Provost K, Soucy JP, Buckley RF, Benzinger TLS, Morris JC, Villemagne VL, Doré V, Sperling RA, Johnson KA, ... ... Poirier J, et al. Association of Elevated Amyloid and Tau Positron Emission Tomography Signal With Near-Term Development of Alzheimer Disease Symptoms in Older Adults Without Cognitive Impairment. Jama Neurology. PMID 35907254 DOI: 10.1001/jamaneurol.2022.2379  0.316
2022 Miron J, Picard C, Labonté A, Auld D, Poirier J. MSR1 and NEP Are Correlated with Alzheimer's Disease Amyloid Pathology and Apolipoprotein Alterations. Journal of Alzheimer's Disease : Jad. PMID 35034907 DOI: 10.3233/JAD-215410  0.364
2021 Nilsson NIV, Picard C, Labonté A, Köbe T, Meyer PF, Villeneuve S, Auld D, Poirier J, For The Prevent-Ad Research Group, Alzheimer's Disease Neuroimaging Initiative. Association of a Total Cholesterol Polygenic Score with Cholesterol Levels and Pathological Biomarkers across the Alzheimer's Disease Spectrum. Genes. 12. PMID 34828411 DOI: 10.3390/genes12111805  0.356
2021 Gonneaud J, Baria AT, Pichet Binette A, Gordon BA, Chhatwal JP, Cruchaga C, Jucker M, Levin J, Salloway S, Farlow M, Gauthier S, Benzinger TLS, Morris JC, Bateman RJ, Breitner JCS, ... Poirier J, et al. Accelerated functional brain aging in pre-clinical familial Alzheimer's disease. Nature Communications. 12: 5346. PMID 34504080 DOI: 10.1038/s41467-021-25492-9  0.34
2021 Pichet Binette A, Theaud G, Rheault F, Roy M, Collins DL, Levin J, Mori H, Lee JH, Farlow MR, Schofield P, Chhatwal JP, Masters CL, Benzinger T, Morris J, Bateman R, ... ... Poirier J, et al. Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer's disease. Elife. 10. PMID 33983116 DOI: 10.7554/eLife.62929  0.358
2020 Gonneaud J, Bedetti C, Binette AP, Benzinger TLS, Morris JC, Bateman RJ, Poirier J, Breitner JCS, Villeneuve S. Association of education with Aβ burden in preclinicial familial and sporadic Alzheimer disease. Neurology. PMID 32759192 DOI: 10.1212/Wnl.0000000000010314  0.429
2020 Pichet Binette A, Vachon-Presseau É, Morris J, Bateman R, Benzinger T, Collins DL, Poirier J, Breitner JCS, Villeneuve S. Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease. Biological Psychiatry. PMID 32228870 DOI: 10.1016/J.Biopsych.2020.01.023  0.419
2020 Therriault J, Benedet AL, Pascoal TA, Mathotaarachchi S, Savard M, Chamoun M, Thomas E, Kang MS, Lussier F, Tissot C, Soucy JP, Massarweh G, Rej S, Saha-Chaudhuri P, Poirier J, et al. APOEε4 potentiates the relationship between amyloid-β and tau pathologies. Molecular Psychiatry. PMID 32161362 DOI: 10.1038/S41380-020-0688-6  0.394
2020 Pichet Binette A, Gonneaud J, Vogel JW, La Joie R, Rosa-Neto P, Collins DL, Poirier J, Breitner JCS, Villeneuve S, Vachon-Presseau E. Morphometric network differences in ageing versus Alzheimer's disease dementia. Brain : a Journal of Neurology. 143: 635-649. PMID 32040564 DOI: 10.1093/Brain/Awz414  0.381
2020 McSweeney M, Pichet Binette A, Meyer PF, Gonneaud J, Bedetti C, Ozlen H, Labonté A, Rosa-Neto P, Breitner J, Poirier J, Villeneuve S. Intermediate flortaucipir uptake is associated with Aβ-PET and CSF-tau in asymptomatic adults. Neurology. PMID 32015176 DOI: 10.1212/Wnl.0000000000008905  0.313
2020 Schmitz TW, Soreq H, Poirier J, Spreng RN. Longitudinal Basal Forebrain Degeneration Interacts with TREM2/C3 Biomarkers of Inflammation in Presymptomatic Alzheimer's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 40: 1931-1942. PMID 31915256 DOI: 10.1523/Jneurosci.1184-19.2019  0.425
2019 Picard C, Poirier A, Bélanger S, Labonté A, Auld D, Poirier J. Proprotein convertase subtilisin/kexin type 9 (PCSK9) in Alzheimer's disease: A genetic and proteomic multi-cohort study. Plos One. 14: e0220254. PMID 31437157 DOI: 10.1371/Journal.Pone.0220254  0.347
2019 Meyer PF, Savard M, Poirier J, Morgan D, Breitner J. Hypothesis: cerebrospinal fluid protein markers suggest a pathway toward symptomatic resilience to AD pathology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31405825 DOI: 10.1016/J.Jalz.2019.05.007  0.338
2019 Miron J, Picard C, Labonté A, Auld D, Breitner J, Poirier J. Association of PPP2R1A with Alzheimer's disease and specific cognitive domains. Neurobiology of Aging. 81: 234-243. PMID 31349112 DOI: 10.1016/J.Neurobiolaging.2019.06.008  0.35
2019 Miron J, Picard C, Lafaille-Magnan MÉ, Savard M, Labonté A, Breitner J, Rosa-Neto P, Auld D, Poirier J. Association of TLR4 with Alzheimer's disease risk and presymptomatic biomarkers of inflammation. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31175027 DOI: 10.1016/J.Jalz.2019.03.012  0.354
2019 Liebsch F, Kulic L, Teunissen C, Shobo A, Ulku I, Engelschalt V, Hancock MA, van der Flier WM, Kunach P, Rosa-Neto P, Scheltens P, Poirier J, Saftig P, Bateman RJ, Breitner J, et al. Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer's disease progression. Nature Communications. 10: 2240. PMID 31110178 DOI: 10.1038/S41467-019-10152-W  0.367
2019 Lleó A, Alcolea D, Martínez-Lage P, Scheltens P, Parnetti L, Poirier J, Simonsen AH, Verbeek MM, Rosa-Neto P, Slot RER, Tainta M, Izaguirre A, Reijs BLR, Farotti L, Tsolaki M, et al. Longitudinal cerebrospinal fluid biomarker trajectories along the Alzheimer's disease continuum in the BIOMARKAPD study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30967340 DOI: 10.1016/J.Jalz.2019.01.015  0.304
2019 Gonneaud J, Baria A, Binette AP, Benzinger TLS, Morris JC, Bateman R, Breitner JCS, Poirier J, Vachon-Presseau E, Villeneuve S. Ic-P-054: Prediction Of Brain Age Using Resting-State Functional Connectivity Reveals Accelerated Aging In The Preclinical Phase Of Autosomal Dominant Alzheimer'S Disease, Irrespectiveof Amyloid Pathology Alzheimers & Dementia. 15: 240. DOI: 10.1016/J.Jalz.2019.06.4897  0.374
2019 Meyer P, Labonte A, Rosa-Neto P, Poirier J, Breitner JCS. O4-11-06: Nsaids For Ad Prevention? Naproxen Enters The Cns Without Apparent Effect On Csf Immune Markers Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4805  0.332
2019 Köbe T, Gonneaud J, Binette AP, Meyer P, McSweeney M, Rosa-Neto P, Breitner JC, Poirier J, Villeneuve S. P1-431: VASCULAR MEDICAL TREATMENTS INFLUENCE THE ASSOCIATION BETWEEN VASCULAR BURDEN AND AMYLOID PATHOLOGY IN ASYMPTOMATIC INDIVIDUALS AT RISK FOR ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P430-P430. DOI: 10.1016/J.Jalz.2019.06.1036  0.377
2018 Miron J, Picard C, Frappier J, Dea D, Théroux L, Poirier J. TLR4 Gene Expression and Pro-Inflammatory Cytokines in Alzheimer's Disease and in Response to Hippocampal Deafferentation in Rodents. Journal of Alzheimer's Disease : Jad. PMID 29782315 DOI: 10.3233/Jad-171160  0.315
2018 Meyer PF, Savard M, Poirier J, Labonté A, Rosa-Neto P, Weitz TM, Town T, Breitner J. Bi-Directional Association of Cerebrospinal Fluid Immune Markers with Stage of Alzheimer's Disease Pathogenesis. Journal of Alzheimer's Disease : Jad. PMID 29660934 DOI: 10.3233/Jad-170887  0.315
2018 Paquette M, Saavedra YGL, Poirier J, Théroux L, Dea D, Baass A, Dufour R. Loss-of-Function PCSK9 Mutations Are Not Associated With Alzheimer Disease. Journal of Geriatric Psychiatry and Neurology. 891988718764330. PMID 29562810 DOI: 10.1177/0891988718764330  0.313
2018 Picard C, Julien C, Frappier J, Miron J, Théroux L, Dea D, Breitner JCS, Poirier J. Alterations in cholesterol metabolism-related genes in sporadic Alzheimer's disease. Neurobiology of Aging. PMID 29503034 DOI: 10.1016/J.Neurobiolaging.2018.01.018  0.353
2018 Pelleieux S, Picard C, Lamarre-Théroux L, Dea D, Leduc V, Tsantrizos YS, Poirier J. Isoprenoids and tau pathology in sporadic Alzheimer's disease. Neurobiology of Aging. 65: 132-139. PMID 29476987 DOI: 10.1016/J.Neurobiolaging.2018.01.012  0.325
2018 Benedet AL, Yu L, Labbe A, Mathotaarachchi S, Pascoal TA, Shin M, Kang MS, Gauthier S, Rouleau GA, Poirier J, Bennett DA, Rosa-Neto P. variant mitigates Alzheimer disease pathophysiology in vivo and postmortem. Neurology. Genetics. 4: e216. PMID 29473050 DOI: 10.1212/Nxg.0000000000000216  0.43
2018 Miron J, Picard C, Nilsson N, Frappier J, Dea D, Théroux L, Poirier J. CDK5RAP2 gene and tau pathophysiology in late-onset sporadic Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29360470 DOI: 10.1016/J.Jalz.2017.12.004  0.363
2018 Nyarko JNK, Quartey MO, Pennington PR, Heistad RM, Dea D, Poirier J, Baker GB, Mousseau DD. Profiles of β-amyloid peptides and key secretases in brain autopsy samples differ with sex and APOE ε4 status: impact for risk and progression of Alzheimer disease. Neuroscience. PMID 29331531 DOI: 10.1016/J.Neuroscience.2018.01.005  0.427
2018 Meyer P, Savard M, Poirier J, Breitner JCS, Initiative ADN. O2-15-05: Csf Immune Markers Predict Decreased Ad Symptom Severity And Progression Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2728  0.304
2018 Gonneaud J, Bedetti C, Binette AP, Benzinger TLS, Morris JC, Bateman RJ, Poirier J, Breitner JCS, Villeneuve S. IC-P-158: GENETIC AND ENVIRONMENTAL FACTORS ARE DIFFERENTIALLY RELATED TO Aβ BURDEN IN THE PRESYMPTOMATIC PHASE OF AUTOSOMAL DOMINANT AND SPORADIC ALZHEIMER'S DISEASE Alzheimers & Dementia. 14: 134. DOI: 10.1016/J.Jalz.2018.06.2225  0.366
2017 Konishi K, Joober R, Poirier J, MacDonald K, Chakravarty M, Patel R, Breitner J, Bohbot VD. Healthy versus Entorhinal Cortical Atrophy Identification in Asymptomatic APOE4 Carriers at Risk for Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 29278888 DOI: 10.3233/Jad-170540  0.339
2017 Tardif CL, Devenyi GA, Amaral RSC, Pelleieux S, Poirier J, Rosa-Neto P, Breitner J, Chakravarty MM. Regionally specific changes in the hippocampal circuitry accompany progression of cerebrospinal fluid biomarkers in preclinical Alzheimer's disease. Human Brain Mapping. PMID 29164798 DOI: 10.1002/Hbm.23897  0.368
2017 Parent MJ, Zimmer ER, Shin M, Kang MS, Fonov VS, Mathieu A, Aliaga A, Kostikov A, Do Carmo S, Dea D, Poirier J, Soucy JP, Gauthier S, Cuello AC, Rosa-Neto P. Multimodal imaging in rat model recapitulates Alzheimer's Disease biomarkers abnormalities. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29097597 DOI: 10.1523/Jneurosci.1346-17.2017  0.344
2017 Tuwaig M, Savard M, Jutras B, Poirier J, Collins DL, Rosa-Neto P, Fontaine D, Breitner JCS. Deficit in Central Auditory Processing as a Biomarker of Pre-Clinical Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 28984583 DOI: 10.3233/Jad-170545  0.331
2017 Schoemaker D, Poirier J, Collins DL, Gauthier S, Pruessner JC. Familiarity deficits in cognitively normal aging individuals with APOE ε4: A follow-up investigation of medial temporal lobe structural correlates. Alzheimer's & Dementia (Amsterdam, Netherlands). 9: 21-24. PMID 28761928 DOI: 10.1016/J.Dadm.2017.05.008  0.311
2017 Lleó A, Alcolea D, Martinez-Lage P, Scheltens P, Parnetti L, Poirier J, Simonsen AH, Verbeek MM, Rosa-Neto P, Slot RER, Tainta M, Izagirre A, Reijs BLR, Farotti L, Fortea J, et al. Longitudinal Cerebrospinal Fluid Biomarker Trajectories Along The Alzheimer'S Disease Continuum: A Multicentre European Study Alzheimers & Dementia. 13: 924. DOI: 10.1016/J.Jalz.2017.07.359  0.386
2017 Picard C, Julien C, Miron J, Théroux L, Dea D, Poirier J. [P2-106]: SREBF2 POLYMORPHISMS AND EXPRESSION LEVELS CORRELATE WITH ALZHEIMER's DISEASE NEUROPATHOLOGY Alzheimer's & Dementia. 13: P647-P647. DOI: 10.1016/J.Jalz.2017.06.756  0.418
2017 Meyer P, Poirier J, Rosa-Neto P, Weitz TM, Town T, Labonte A, Breitner JCS. Increased Pro-Inflammatory Signaling And Evidence Of Alzheimer’S Disease Pathology In Healthy Older Adults At Risk For Ad Alzheimers & Dementia. 13: 608. DOI: 10.1016/J.Jalz.2017.06.659  0.352
2017 Kang MS, Shin M, Zimmer ER, Mathotaarachchi SS, Pascoal TA, Ng KP, Therriault J, Devenyi G, Chakravarty M, Blennow K, Zetterberg H, Soucy J, Poirier J, Gauthier S, Cuello AC, et al. Elevated Csf Levels Of Neurofilament Light Chain Is Associated With Gray Matter Neurodegeneration In Both Humans And Transgenic Rat Model Of Alzheimer’S Disease Alzheimers & Dementia. 13: 41. DOI: 10.1016/J.Jalz.2017.06.2320  0.319
2017 Théroux L, Pelleieux S, Tsantrizos Y, Dea D, Poirier J. [P4-147]: ISOPRENOIDS PATHWAY, TAU PHOSPHORYLATION AND ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P1314-P1314. DOI: 10.1016/J.Jalz.2017.06.2013  0.375
2017 Dea D, Théroux L, Leduc V, Labonte A, Nilsson NI, Poirier J. [P4-140]: HMG COA REDUCTASE IS A GENETIC MODIFIER FOR RISK, AGE OF ONSET AND ALZHEIMER's DISEASE's CONVERSION WHICH MODULATES PATHOLOGY-RELATED AD BIOMARKERS Alzheimer's & Dementia. 13: P1310-P1311. DOI: 10.1016/J.Jalz.2017.06.2006  0.44
2017 Lafaille-Magnan M, Picard C, Miron J, Poirier J, Breitner JCS. Candidate Gene Studies And Gwas Suggest Substantial Genetic Influence On Deficits In Olfactory Identification Among Persons At Risk Of Ad Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.1945  0.321
2017 Binette AP, Vachon-Presseau É, Joie RL, Poirier J, Rosa-Neto P, Collins L, Breitner JCS, Villeneuve S. Moving Away From Single Ad-Signature Roi: Assessing The Relationship Between Whole-Brain Gray Matter Pattern, Ad Pathology, And Cognition In Healthy Elderly At Risk Of Ad Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.1579  0.422
2016 Konishi K, Bhat V, Banner H, Poirier J, Joober R, Bohbot VD. APOE2 Is Associated with Spatial Navigational Strategies and Increased Gray Matter in the Hippocampus. Frontiers in Human Neuroscience. 10: 349. PMID 27468260 DOI: 10.3389/fnhum.2016.00349  0.303
2016 Schoemaker D, Poirier J, Escobar S, Gauthier S, Pruessner J. Selective familiarity deficits in otherwise cognitively intact aging individuals with genetic risk for Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 2: 132-9. PMID 27239534 DOI: 10.1016/J.Dadm.2015.11.007  0.35
2016 Rosa-Neto P, Pascoal TA, Frenette J, Tremblay-Mercier J, Labonté A, Poirrier I, Khoury RE, Ferdinand F, Poirier J, Breitner JCS. The Effect Of Lumbar Puncture On The Retention Of The Prevent-Ad Cohort Ad Alzheimers & Dementia. 12: 1152. DOI: 10.1016/J.Jalz.2016.07.053  0.395
2016 Breitner JCS, Poirier J, Town T, Rosa-Neto P, Tremblay-Mercier J, Weitz TM. Csf Markers Of Inflammation And Alzheimer'S Disease Pathogenesis In The Cognitively Intact Prevent-Ad Cohort Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.470  0.44
2016 Binette AP, Vogel JW, Fonov VS, Madjar C, Tremblay-Mercier J, Breitner JCS, Collins L, Poirier J, Villeneuve S. High Csf Tau Is Related To Reduced Hippocampal Volume And Subjective Cognitive Decline In Healthy Elderly With Amyloid Pathology Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.168  0.347
2016 Pelleieux S, Tsantrizos Y, Theroux L, Dea D, Poirier J. P2-124: Brain Isoprenoids and Alzheimer's Disease Alzheimer's & Dementia. 12: P659-P659. DOI: 10.1016/J.Jalz.2016.06.1494  0.411
2015 Benedet AL, Labbe A, Lemay P, Zimmer ER, Pascoal TA, Leuzy A, Mathotaarachchi S, Mohades S, Shin M, Dionne-Laporte A, Beaudry T, Picard C, Gauthier S, Poirier J, Rouleau G, et al. Epistasis analysis links immune cascades and cerebral amyloidosis. Journal of Neuroinflammation. 12: 227. PMID 26626881 DOI: 10.1186/S12974-015-0436-Z  0.32
2015 Leduc V, Théroux L, Dea D, Dufour R, Poirier J. Effects of rs3846662 Variants on HMGCR mRNA and Protein Levels and on Markers of Alzheimer's Disease Pathology. Journal of Molecular Neuroscience : Mn. PMID 26541602 DOI: 10.1007/s12031-015-0666-7  0.33
2015 Leduc V, De Beaumont L, Théroux L, Dea D, Aisen P, Petersen RC, Dufour R, Poirier J. HMGCR is a genetic modifier for risk, age of onset and MCI conversion to Alzheimer's disease in a three cohorts study. Molecular Psychiatry. 20: 867-73. PMID 25023145 DOI: 10.1038/Mp.2014.81  0.373
2015 Orban P, Urchs S, Savard M, Madjar C, Tam A, Theroux L, Evans AC, Rosa-Neto P, Collins DL, Poirier J, Breitner JCS, Bellec P. Functional brain network subtypes are associated with Alzheimer's disease biomarkers in an aging, high-risk, cognitively normal cohort: The prevent-alzheimer's disease study Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.289  0.418
2015 Poirier J, Labonté A, Dea D, Tremblay-Mercier J, Savard M, Rosa-Neto P, Etienne PE, Bellec P, Breitner JCS. Mapping the progression of CSF and imaging biomarkers in “at-risk” healthy subjects: The prevent-ad program Alzheimers & Dementia. 11: 118. DOI: 10.1016/J.Jalz.2015.07.016  0.31
2015 Breitner JCS, Albert MS, Poirier J, Etienne PE. Potential of ad biomarkers to reveal the presymptomatic disease process and the effects of treatments that may retard it Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.014  0.386
2015 Miron J, Frappier J, Picard C, Poirier J. P2-014: Analysis of novel genetic factors associated with tau metabolism in the late-onset form of sporadic Alzheimer's disease Alzheimer's & Dementia. 11: P486-P486. DOI: 10.1016/J.Jalz.2015.06.550  0.391
2015 Lafaille-Magnan M, Rosa-Neto P, Labonté A, Poirier J, Breitner JCS. Olfactory identification is associated with CSF tau/abeta42 ratios in cognitively normal adults at high risk of Alzheimer's disease Alzheimers & Dementia. 11: 346. DOI: 10.1016/J.Jalz.2015.06.221  0.392
2015 Tremblay-Mercier J, Lafaille-Magnan M, Savard M, Pascoal TA, Labonté A, Fontaine D, Rosa-Neto P, Poirier J, Breitner J. Cerebrospinal fluid ad biomarkers predict poorer cognitive performance in a cognitively intact cohort at risk of Alzheimer’s dementia: The prevent-ad program Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.06.1739  0.354
2015 Pascoal TA, Dadar M, Manitsirikul S, Breitner JCS, Collins DL, Poirier J, Labonté A, Rosa-Neto P. Association between apolipoprotein a-i levels and white matter hyperintensities depends on CSF tau levels in a high-risk cohort of aging cognitively normal persons: The prevent-alzheimer's disease study Alzheimers & Dementia. 11: 103. DOI: 10.1016/J.Jalz.2015.06.1001  0.4
2014 Poirier J, Miron J, Picard C, Gormley P, Théroux L, Breitner J, Dea D. Apolipoprotein E and lipid homeostasis in the etiology and treatment of sporadic Alzheimer's disease. Neurobiology of Aging. 35: S3-10. PMID 24973118 DOI: 10.1016/J.Neurobiolaging.2014.03.037  0.437
2014 De Schutter JW, Park J, Leung CY, Gormley P, Lin YS, Hu Z, Berghuis AM, Poirier J, Tsantrizos YS. Multistage screening reveals chameleon ligands of the human farnesyl pyrophosphate synthase: implications to drug discovery for neurodegenerative diseases. Journal of Medicinal Chemistry. 57: 5764-76. PMID 24911527 DOI: 10.1021/Jm500629E  0.321
2014 Tremblay-Mercier J, Madjar C, Etienne P, Poirier J, Breitner JC. P4-070: A PROGRAM OF PRE-SYMPTOMATIC EVALUATION OF EXPERIMENTAL OR NOVEL TREATMENTS FOR ALZHEIMER'S DISEASE (PREVENT-AD): DESIGN, METHODS, AND PERSPECTIVES Alzheimer's & Dementia. 10: P808-P808. DOI: 10.1016/J.Jalz.2014.05.1585  0.391
2014 Lafaille-Magnan M, Collins L, Fonov V, Fontaine D, Etienne P, Poirier J, Breitner JCS. Association Of Olfactory Performance And Hippocampal Volume In Persons At Risk Of Alzheimer'S Dementia Alzheimers & Dementia. 10: 519. DOI: 10.1016/J.Jalz.2014.05.155  0.36
2014 Poirier J, Miron J, Picard C. Pharmacogenomic Approaches to the Treatment of Sporadic Alzheimer Disease using Cholinomimetic Agents Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease: Fifth Edition. 51-62. DOI: 10.1016/B978-0-12-410529-4.00004-8  0.341
2012 Domenger D, Dea D, Theroux L, Moquin L, Gratton A, Poirier J. The MPTP neurotoxic lesion model of Parkinson's disease activates the apolipoprotein E cascade in the mouse brain. Experimental Neurology. 233: 513-22. PMID 22155743 DOI: 10.1016/J.Expneurol.2011.11.031  0.484
2011 Henderson ST, Poirier J. Pharmacogenetic analysis of the effects of polymorphisms in APOE, IDE and IL1B on a ketone body based therapeutic on cognition in mild to moderate Alzheimer's disease; a randomized, double-blind, placebo-controlled study. Bmc Medical Genetics. 12: 137. PMID 21992747 DOI: 10.1186/1471-2350-12-137  0.33
2011 Leduc V, Legault V, Dea D, Poirier J. Normalization of gene expression using SYBR green qPCR: a case for paraoxonase 1 and 2 in Alzheimer's disease brains. Journal of Neuroscience Methods. 200: 14-9. PMID 21672555 DOI: 10.1016/J.Jneumeth.2011.05.026  0.428
2011 Leduc V, Domenger D, De Beaumont L, Lalonde D, Bélanger-Jasmin S, Poirier J. Function and comorbidities of apolipoprotein e in Alzheimer's disease. International Journal of Alzheimer's Disease. 2011: 974361. PMID 21559182 DOI: 10.4061/2011/974361  0.396
2010 Leduc V, Jasmin-Bélanger S, Poirier J. APOE and cholesterol homeostasis in Alzheimer's disease. Trends in Molecular Medicine. 16: 469-77. PMID 20817608 DOI: 10.1016/J.Molmed.2010.07.008  0.486
2010 Dea D, Théroux L, Legault V, Leduc V, Poirier J. P1-061: HMG-CoA reductase as a risk factor and modulator of Alzheimer pathology Alzheimer's & Dementia. 6: S191-S191. DOI: 10.1016/J.Jalz.2010.05.609  0.34
2009 Leduc V, Théroux L, Dea D, Robitaille Y, Poirier J. Involvement of paraoxonase 1 genetic variants in Alzheimer's disease neuropathology. The European Journal of Neuroscience. 30: 1823-30. PMID 19863653 DOI: 10.1111/J.1460-9568.2009.06983.X  0.472
2009 Gauthier S, Poirier J. Commentary on "A roadmap for the prevention of dementia II. Leon Thal Symposium 2008." Who may benefit from disease-modifying studies in Alzheimer's disease? Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 5: 147-8. PMID 19328447 DOI: 10.1016/J.Jalz.2009.01.007  0.342
2009 Fiocco AJ, Nair NPV, Schwartz G, Ng Ying Kin F, Joober R, Poirier J, Lupien SJ. Influence of genetic polymorphisms in the apolipoprotein (APOE) and the butyrylcholinesterase (BCHE) gene on stress markers in older adults: A 3-year study Neurobiology of Aging. 30: 1001-1005. PMID 17996334 DOI: 10.1016/J.Neurobiolaging.2007.09.008  0.316
2008 Burgess BL, Parkinson PF, Racke MM, Hirsch-Reinshagen V, Fan J, Wong C, Stukas S, Theroux L, Chan JY, Donkin J, Wilkinson A, Balik D, Christie B, Poirier J, Lütjohann D, et al. ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo. Journal of Lipid Research. 49: 1254-67. PMID 18314463 DOI: 10.1194/Jlr.M700481-Jlr200  0.482
2008 Aleong R, Blain JF, Poirier J. Pro-inflammatory cytokines modulate glial apolipoprotein E secretion. Current Alzheimer Research. 5: 33-7. PMID 18288929 DOI: 10.2174/156720508783884666  0.364
2008 Poirier J, Gauthier S. Pharmacogenomics and the treatment of sporadic Alzheimer's disease: A decade of progress Current Pharmacogenomics and Personalized Medicine. 6: 63-76. DOI: 10.2174/187569208784017494  0.52
2007 Petit-Turcotte C, Aumont N, Blain JF, Poirier J. Apolipoprotein E receptors and amyloid expression are modulated in an apolipoprotein E-dependent fashion in response to hippocampal deafferentation in rodent. Neuroscience. 150: 58-63. PMID 17935896 DOI: 10.1016/J.Neuroscience.2007.05.021  0.795
2006 Blain JF, Aumont N, Théroux L, Dea D, Poirier J. A polymorphism in lipoprotein lipase affects the severity of Alzheimer's disease pathophysiology. The European Journal of Neuroscience. 24: 1245-51. PMID 16965549 DOI: 10.1111/J.1460-9568.2006.05007.X  0.482
2006 Kar S, Poirier J, Guevara J, Dea D, Hawkes C, Robitaille Y, Quirion R. Cellular distribution of insulin-like growth factor-II/mannose-6-phosphate receptor in normal human brain and its alteration in Alzheimer's disease pathology. Neurobiology of Aging. 27: 199-210. PMID 16399207 DOI: 10.1016/J.Neurobiolaging.2005.03.005  0.436
2006 Blain JF, Sullivan PM, Poirier J. A deficit in astroglial organization causes the impaired reactive sprouting in human apolipoprotein E4 targeted replacement mice. Neurobiology of Disease. 21: 505-14. PMID 16171999 DOI: 10.1016/J.Nbd.2005.08.010  0.432
2005 Hirsch-Reinshagen V, Maia LF, Burgess BL, Blain JF, Naus KE, McIsaac SA, Parkinson PF, Chan JY, Tansley GH, Hayden MR, Poirier J, Van Nostrand W, Wellington CL. The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease. The Journal of Biological Chemistry. 280: 43243-56. PMID 16207707 DOI: 10.1074/Jbc.M508781200  0.406
2005 Champagne D, Rochford J, Poirier J. Effect of apolipoprotein E deficiency on reactive sprouting in the dentate gyrus of the hippocampus following entorhinal cortex lesion: role of the astroglial response. Experimental Neurology. 194: 31-42. PMID 15899241 DOI: 10.1016/J.Expneurol.2005.01.016  0.715
2005 Gaudreault SB, Blain JF, Gratton JP, Poirier J. A role for caveolin-1 in post-injury reactive neuronal plasticity. Journal of Neurochemistry. 92: 831-9. PMID 15686485 DOI: 10.1111/J.1471-4159.2004.02917.X  0.355
2005 Poirier J. Apolipoprotein E, cholesterol transport and synthesis in sporadic Alzheimer's disease. Neurobiology of Aging. 26: 355-61. PMID 15639314 DOI: 10.1016/J.Neurobiolaging.2004.09.003  0.525
2005 Petit-Turcotte C, Aumont N, Beffert U, Dea D, Herz J, Poirier J. The apoE receptor apoER2 is involved in the maintenance of efficient synaptic plasticity. Neurobiology of Aging. 26: 195-206. PMID 15582748 DOI: 10.1016/J.Neurobiolaging.2004.04.007  0.765
2004 Blain JF, Poirier J. Cholesterol homeostasis and the pathophysiology of Alzheimer's disease. Expert Review of Neurotherapeutics. 4: 823-9. PMID 15853509 DOI: 10.1586/14737175.4.5.823  0.344
2004 Gaudreault SB, Dea D, Poirier J. Increased caveolin-1 expression in Alzheimer's disease brain. Neurobiology of Aging. 25: 753-9. PMID 15165700 DOI: 10.1016/j.neurobiolaging.2003.07.004  0.384
2004 Evans RM, Hui S, Perkins A, Lahiri DK, Poirier J, Farlow MR. Cholesterol and APOE genotype interact to influence Alzheimer disease progression. Neurology. 62: 1869-71. PMID 15159498 DOI: 10.1212/01.Wnl.0000125323.15458.3F  0.39
2004 Blain JF, Paradis E, Gaudreault SB, Champagne D, Richard D, Poirier J. A role for lipoprotein lipase during synaptic remodeling in the adult mouse brain. Neurobiology of Disease. 15: 510-9. PMID 15056458 DOI: 10.1016/J.Nbd.2003.12.001  0.715
2004 Blain J, Sullivan PM, Poirier J. P2-085 Response to brain injury in human apolipoprotein E targeted replacement mice is genotype-specific Neurobiology of Aging. 25: S248. DOI: 10.1016/S0197-4580(04)80832-7  0.329
2003 Aleong R, Aumont N, Dea D, Poirier J. Non-steroidal anti-inflammatory drugs mediate increased in vitro glial expression of apolipoprotein E protein. The European Journal of Neuroscience. 18: 1428-38. PMID 14511323 DOI: 10.1046/J.1460-9568.2003.02869.X  0.478
2003 Champagne D, Pearson D, Dea D, Rochford J, Poirier J. The cholesterol-lowering drug probucol increases apolipoprotein E production in the hippocampus of aged rats: implications for Alzheimer's disease. Neuroscience. 121: 99-110. PMID 12946703 DOI: 10.1016/S0306-4522(03)00361-0  0.754
2003 Poirier J. Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease. Trends in Molecular Medicine. 9: 94-101. PMID 12657430 DOI: 10.1016/S1471-4914(03)00007-8  0.431
2002 de Leon MJ, Segal S, Tarshish CY, DeSanti S, Zinkowski R, Mehta PD, Convit A, Caraos C, Rusinek H, Tsui W, Saint Louis LA, DeBernardis J, Kerkman D, Qadri F, Gary A, ... ... Poirier J, et al. Longitudinal cerebrospinal fluid tau load increases in mild cognitive impairment. Neuroscience Letters. 333: 183-6. PMID 12429378 DOI: 10.1016/S0304-3940(02)01038-8  0.32
2002 Champagne D, Dupuy JB, Rochford J, Poirier J. Apolipoprotein E knockout mice display procedural deficits in the Morris water maze: analysis of learning strategies in three versions of the task. Neuroscience. 114: 641-54. PMID 12220566 DOI: 10.1016/S0306-4522(02)00313-5  0.674
2002 Zetterberg H, Palmér M, Ricksten A, Poirier J, Palmqvist L, Rymo L, Zafiropoulos A, Arvanitis DA, Spandidos DA, Blennow K. Influence of the apolipoprotein E epsilon4 allele on human embryonic development. Neuroscience Letters. 324: 189-92. PMID 12009520 DOI: 10.1016/S0304-3940(02)00198-2  0.397
2002 Danik M, Poirier J. Chapter 4 Apolipoprotein E and lipid mobilization in neuronal membrane remodeling and its relevance to Alzheimer's disease New Comprehensive Biochemistry. 35: 53-66. DOI: 10.1016/S0167-7306(02)35033-6  0.391
2001 Petit-Turcotte C, Stohl SM, Beffert U, Cohn JS, Aumont N, Tremblay M, Dea D, Yang L, Poirier J, Shachter NS. Apolipoprotein C-I expression in the brain in Alzheimer's disease. Neurobiology of Disease. 8: 953-63. PMID 11741391 DOI: 10.1006/Nbdi.2001.0441  0.79
2001 Vaucher E, Aumont N, Pearson D, Rowe W, Poirier J, Kar S. Amyloid beta peptide levels and its effects on hippocampal acetylcholine release in aged, cognitively-impaired and -unimpaired rats. Journal of Chemical Neuroanatomy. 21: 323-9. PMID 11429273 DOI: 10.1016/S0891-0618(01)00120-X  0.397
2001 Ramassamy C, Krzywkowski P, Averill D, Lussier-Cacan S, Theroux L, Christen Y, Davignon J, Poirier J. Impact of apoE deficiency on oxidative insults and antioxidant levels in the brain Molecular Brain Research. 86: 76-83. PMID 11165374 DOI: 10.1016/S0169-328X(00)00268-0  0.323
2000 Poirier J. Apolipoprotein E and Alzheimer's disease a role in amyloid catabolism Annals of the New York Academy of Sciences. 924: 81-90. PMID 11193807  0.422
2000 Patrick CB, Krzywkowski P, Ramassamy C, Poirier J, Rapoport SI, Murphy EJ. Phospholipase A2 activity is decreased selectively in the hippocampus of aged apolipoprotein E deficient mice. Neuroscience Letters. 288: 211-4. PMID 10889345 DOI: 10.1016/S0304-3940(00)01240-4  0.341
2000 Ramassamy C, Averill D, Beffert U, Theroux L, Lussier-Cacan S, Cohn JS, Christen Y, Schoofs A, Davignon J, Poirier J. Oxidative insults are associated with apolipoprotein E genotype in Alzheimer's disease brain. Neurobiology of Disease. 7: 23-37. PMID 10671320 DOI: 10.1006/Nbdi.1999.0273  0.753
2000 Petit-Turcotte C, Beffert U, Schachter NS, Cohn JS, Aumont N, Poirier J. Cerebral expression of APOE and apoc-I in Alzheimer's disease in relation to ϵ4 and H2 polymorphic alleles Neurobiology of Aging. 21: 205. DOI: 10.1016/S0197-4580(00)83250-9  0.773
2000 Poirier J, Panisset M. APOE as therapeutic target for the treatment of Alzheimer's disease Neurobiology of Aging. 21: 139. DOI: 10.1016/S0197-4580(00)82423-9  0.399
2000 Dea D, Aumont N, Poirier J. Apo E and apo E receptor gene expression in the brain of Alzheimer's disease subjects with different apoE genotype Neurobiology of Aging. 21: 115. DOI: 10.1016/S0197-4580(00)82315-5  0.471
1999 Danik M, Champagne D, Petit-Turcotte C, Beffert U, Poirier J. Brain lipoprotein metabolism and its relation to neurodegenerative disease. Critical Reviews in Neurobiology. 13: 357-407. PMID 11028681 DOI: 10.1615/Critrevneurobiol.V13.I4.20  0.749
1999 Poirier J. Apolipoprotein E: A pharmacogenetic target for the treatment of Alzheimer's disease Molecular Diagnosis. 4: 335-341. PMID 10671644 DOI: 10.1016/S1084-8592(99)80010-1  0.415
1999 Bretsky PM, Buckwalter JG, Seeman TE, Miller CA, Poirier J, Schellenberg GD, Finch CE, Henderson VW. Evidence for an interaction between apolipoprotein E genotype, gender, and Alzheimer disease. Alzheimer Disease and Associated Disorders. 13: 216-21. PMID 10609670 DOI: 10.1097/00002093-199910000-00007  0.337
1999 Beffert U, Cohn JS, Petit-Turcotte C, Tremblay M, Aumont N, Ramassamy C, Davignon J, Poirier J. Apolipoprotein E and beta-amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are disease-related and apolipoprotein E genotype dependent. Brain Research. 843: 87-94. PMID 10528114 DOI: 10.1016/S0006-8993(99)01894-6  0.801
1999 Ramassamy C, Averill D, Beffert U, Bastianetto S, Theroux L, Lussier-Cacan S, Cohn JS, Christen Y, Davignon J, Quirion R, Poirier J. Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype. Free Radical Biology & Medicine. 27: 544-53. PMID 10490274 DOI: 10.1016/S0891-5849(99)00102-1  0.727
1999 Krzywkowski P, Ghribi O, Gagné J, Chabot C, Kar S, Rochford J, Massicotte G, Poirier J. Cholinergic systems and long-term potentiation in memory-impaired apolipoprotein E-deficient mice. Neuroscience. 92: 1273-86. PMID 10426483 DOI: 10.1016/S0306-4522(99)00061-5  0.404
1999 Terrisse L, Séguin D, Bertrand P, Poirier J, Milne R, Rassart E. Modulation of apolipoprotein D and apolipoprotein E expression in rat hippocampus after entorhinal cortex lesion. Brain Research. Molecular Brain Research. 70: 26-35. PMID 10381540 DOI: 10.1016/S0169-328X(99)00123-0  0.429
1999 Beffert U, Aumont N, Dea D, Lussier-Cacan S, Davignon J, Poirier J. Apolipoprotein E isoform-specific reduction of extracellular amyloid in neuronal cultures. Brain Research. Molecular Brain Research. 68: 181-5. PMID 10320795 DOI: 10.1016/S0169-328X(99)00073-X  0.745
1999 Poirier J. Apolipoprotein E4, cholinergic integrity and the pharmacogenetics of Alzheimer's disease Journal of Psychiatry and Neuroscience. 24: 147-153. PMID 10212558  0.432
1999 Beffert U, Arguin C, Poirier J. The polymorphism in exon 3 of the low density lipoprotein receptor-related protein gene is weakly associated with Alzheimer's disease. Neuroscience Letters. 259: 29-32. PMID 10027548 DOI: 10.1016/S0304-3940(98)00888-X  0.75
1998 Beffert U, Poirier J. ApoE associated with lipid has a reduced capacity to inhibit beta-amyloid fibril formation. Neuroreport. 9: 3321-3. PMID 9831470 DOI: 10.1097/00001756-199810050-00031  0.727
1998 Terrisse L, Poirier J, Bertrand P, Merched A, Visvikis S, Siest G, Milne R, Rassart E. Increased levels of apolipoprotein D in cerebrospinal fluid and hippocampus of Alzheimer's patients. Journal of Neurochemistry. 71: 1643-50. PMID 9751198 DOI: 10.1046/J.1471-4159.1998.71041643.X  0.351
1998 Lambert JC, Berr C, Pasquier F, Delacourte A, Frigard B, Cottel D, Pérez-Tur J, Mouroux V, Mohr M, Cécyre D, Galasko D, Lendon C, Poirier J, Hardy J, Mann D, et al. Pronounced impact of Th1/E47cs mutation compared with -491 AT mutation on neural APOE gene expression and risk of developing Alzheimer's disease. Human Molecular Genetics. 7: 1511-6. PMID 9700208 DOI: 10.1093/Hmg/7.9.1511  0.324
1998 Danik M, Poirier J. Apolipoprotein E and neuronal plasticity following experimental de-afferentation and in Alzheimer's disease Biochemical Society Transactions. 26: 262-266. PMID 9649759 DOI: 10.1042/BST0260262  0.312
1998 Beffert U, Bertrand P, Champagne D, Gauthier S, Poirier J. HSV-1 in brain and risk of Alzheimer's disease. Lancet. 351: 1330-1. PMID 9643802 DOI: 10.1016/S0140-6736(05)79057-7  0.783
1998 Beffert U, Danik M, Krzywkowski P, Ramassamy C, Berrada F, Poirier J. The neurobiology of apolipoproteins and their receptors in the CNS and Alzheimer's disease. Brain Research. Brain Research Reviews. 27: 119-42. PMID 9622609 DOI: 10.1016/S0165-0173(98)00008-3  0.728
1998 Beffert U, Aumont N, Dea D, Lussier-Cacan S, Davignon J, Poirier J. Beta-amyloid peptides increase the binding and internalization of apolipoprotein E to hippocampal neurons. Journal of Neurochemistry. 70: 1458-66. PMID 9523562 DOI: 10.1046/J.1471-4159.1998.70041458.X  0.708
1998 Farlow MR, Lahiri DK, Poirier J, Davignon J, Schneider L, Hui SL. Treatment outcome of tacrine therapy depends on apolipoprotein genotype and gender of the subjects with Alzheimer's disease. Neurology. 50: 669-77. PMID 9521254 DOI: 10.1212/Wnl.50.3.669  0.309
1998 Thiffault C, Quirion R, Poirier J. Effect of the MAO-B inhibitor, MDL72974, on superoxide dismutase activity and lipid peroxidation levels in the mouse brain. Synapse (New York, N.Y.). 28: 208-11. PMID 9488505 DOI: 10.1002/(Sici)1098-2396(199803)28:3<208::Aid-Syn3>3.0.Co;2-E  0.344
1997 Nalbantoglu J, Tirado-Santiago G, Lahsaïni A, Poirier J, Goncalves O, Verge G, Momoli F, Welner SA, Massicotte G, Julien JP, Shapiro ML. Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein. Nature. 387: 500-5. PMID 9168112 DOI: 10.1038/387500A0  0.32
1997 Gauthier S, Panisset M, Poirier J. Advances in the diagnosis of Alzheimer's disease Biological Psychiatry. 42: 1-6. DOI: 10.1016/S0006-3223(97)87493-8  0.397
1996 Farlow MR, Lahiri DK, Poirier J, Davignon J, Hui S. Apolipoprotein E genotype and gender influence response to tacrine therapy. Annals of the New York Academy of Sciences. 802: 101-10. PMID 8993489 DOI: 10.1111/J.1749-6632.1996.Tb32603.X  0.436
1996 Poirier J. Apolipoprotein E in the brain and its role in alzheimer's disease Journal of Psychiatry and Neuroscience. 21: 128-134. PMID 8820179  0.442
1996 Guillaume D, Bertrand P, Dea D, Davignon J, Poirier J. Apolipoprotein E and low-density lipoprotein binding and internalization in primary cultures of rat astrocytes: Isoform-specific alterations Journal of Neurochemistry. 66: 2410-2418. PMID 8632164 DOI: 10.1046/J.1471-4159.1996.66062410.X  0.444
1996 Beffert U, Poirier J. Apolipoprotein E, plaques, tangles and cholinergic dysfunction in Alzheimer's disease. Annals of the New York Academy of Sciences. 777: 166-74. PMID 8624080 DOI: 10.1111/J.1749-6632.1996.Tb34415.X  0.773
1996 Poirier J, Beffert U, Quirion R, Krzywkowski P, Dea D, Aumont N. 331 Apolipoprotein E4 modulate cholinergic activity in Alzheimer's disease and beta-amyloid 1–40 and 25–35 modulate apolipoprotein E metabolism in primary neuronal cell culture Neurobiology of Aging. 17: S83. DOI: 10.1016/S0197-4580(96)80333-2  0.724
1996 Poirier J. 296 Neurobiology of apolipoprotein E: A role in synaptic plasticity and integrity in the injured CNS and in Alzheimer's disease Neurobiology of Aging. 17: S74-S75. DOI: 10.1016/S0197-4580(96)80298-3  0.303
1996 Poirier J, Quirion R, Krzywkowski P, Dea D, Aumont N. 24 Apolipoprotein E4 modulates cholinergic activity and cholinergic drug responsiveness in Alzheimer's disease but demonstrates impaired regulation in vivo Neurobiology of Aging. 17: S7. DOI: 10.1016/S0197-4580(96)80026-1  0.408
1995 Bertrand P, Poirier J, Oda T, Finch CE, Pasinetti GM. Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease. Brain Research. Molecular Brain Research. 33: 174-8. PMID 8774959 DOI: 10.1016/0169-328X(95)00097-C  0.426
1995 Poirier J, Beffert U, Dea D, Alonso R, O'Donnell D, Boksa P. Increased levels of statin, a marker of cell cycle arrest, in response to hippocampal neuronal injury. Brain Research. Molecular Brain Research. 34: 57-64. PMID 8750861 DOI: 10.1016/0169-328X(95)00134-E  0.684
1995 Poirier J, Minnich A, Davignon J. Apolipoprotein E, synaptic plasticity and Alzheimer's disease Annals of Medicine. 27: 663-670. PMID 8652146 DOI: 10.3109/07853899509019253  0.348
1995 Poirier J, Delisle MC, Quirion R, Aubert I, Farlow M, Lahiri D, Hui S, Bertrand P, Nalbantoglu J, Gilfix BM, Gauthier S. Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 92: 12260-4. PMID 8618881 DOI: 10.1073/Pnas.92.26.12260  0.408
1994 Aubert I, Poirier J, Gauthier S, Quirion R. Multiple cholinergic markers are unexpectedly not altered in the rat dentate gyrus following entorhinal cortex lesions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 2476-84. PMID 8182423 DOI: 10.1523/Jneurosci.14-05-02476.1994  0.328
1994 Nalbantoglu J, Gilfix BM, Bertrand P, Robitaille Y, Gauthier S, Rosenblatt DS, Poirier J. Predictive value of apolipoprotein E genotyping in Alzheimer's disease: results of an autopsy series and an analysis of several combined studies. Annals of Neurology. 36: 889-95. PMID 7998776 DOI: 10.1002/Ana.410360614  0.493
1994 Parent A, Poirier J, Baccichet A, Quirion R. Regulation of 1,4,5-IP3, 1,3,4,5-IP4 and IP6 binding sites following entorhinal cortex lesions in rat brain. Neuroscience. 61: 565-73. PMID 7969930 DOI: 10.1016/0306-4522(94)90434-0  0.306
1994 Alonso R, Poirier J, O'Donnell D, Buisson N, Diorio J, Boksa P, Quirion R. Statin, a marker of cell cycle arrest, is overexpressed during the early phase of delayed NMDA toxicity in hippocampal cell cultures. Molecular and Cellular Neurosciences. 5: 530-9. PMID 7704426 DOI: 10.1006/Mcne.1994.1065  0.303
1994 Poirier J. Apolipoprotein E in animal models of CNS injury and in alzheimer's disease Trends in Neurosciences. 17: 525-530. PMID 7532337 DOI: 10.1016/0166-2236(94)90156-2  0.415
1993 Parent A, Dea D, Quirion R, Poirier J. [3H]phorbol ester binding sites and neuronal plasticity in the hippocampus following entorhinal cortex lesions. Brain Research. 607: 23-32. PMID 8481798 DOI: 10.1016/0006-8993(93)91485-B  0.317
1993 O'Donnell D, Baccichet A, Seckl JR, Meaney MJ, Poirier J. Entorhinal cortex lesions transiently alter glucocorticoid but not mineralocorticoid receptor gene expression in the rat hippocampus. Journal of Neurochemistry. 61: 356-9. PMID 8390564 DOI: 10.1111/J.1471-4159.1993.Tb03577.X  0.467
1993 Poirier J, Bertrand P, Kogan S, Gauthier S, Davignon J, Bouthillier D. Apolipoprotein E polymorphism and Alzheimer's disease The Lancet. 342: 697-699. PMID 8103819 DOI: 10.1016/0140-6736(93)91705-Q  0.4
1987 Poirier J, Barbeau A. Erythrocyte antioxidant activity in human patients with Parkinson's disease Neuroscience Letters. 75: 345-348. PMID 3587738 DOI: 10.1016/0304-3940(87)90547-7  0.321
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