Daniel E. Koshland, Jr., Ph.D. - Publications

Affiliations: 
1951-1965 Biochemistry Brookhaven National Laboratory, Upton, NY, United States 
 1965- Biochemistry University of California, Berkeley, Berkeley, CA 
Area:
enzyme reaction mechanisms
Website:
http://dx.doi.org/10.1073/pnas.0707644104

305 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2007 Koshland DE. The Cha-Cha-Cha theory of scientific discovery Science. 317: 761-762. PMID 17690282 DOI: 10.1126/science.1147166  1
2006 Radisky ES, Lee JM, Lu CJ, Koshland DE. Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates. Proceedings of the National Academy of Sciences of the United States of America. 103: 6835-40. PMID 16636277 DOI: 10.1073/Pnas.0601910103  1
2005 Radisky ES, Lu CJ, Kwan G, Koshland DE. Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2. Biochemistry. 44: 6823-30. PMID 15865427 DOI: 10.1021/Bi047301W  1
2004 Koshland DE. Crazy, but correct Nature. 432: 447. PMID 15565132 DOI: 10.1038/432447a  1
2004 Radisky ES, Kwan G, Karen Lu CJ, Koshland DE. Binding, proteolytic, and crystallographic analyses of mutations at the protease-inhibitor interface of the subtilisin BPN'/chymotrypsin inhibitor 2 complex. Biochemistry. 43: 13648-56. PMID 15504027 DOI: 10.1021/Bi048797K  1
2003 Radisky ES, King DS, Kwan G, Koshland DE. The role of the protein core in the inhibitory power of the classic serine protease inhibitor, chymotrypsin inhibitor 2. Biochemistry. 42: 6484-92. PMID 12767231 DOI: 10.1021/Bi034275D  1
2003 Yu EW, McDermott G, Zgurskaya HI, Nikaido H, Koshland DE. Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump Science. 300: 976-980. PMID 12738864 DOI: 10.1126/Science.1083137  1
2002 Koshland DE. The application and usefulness of the ratio kcat/KM Bioorganic Chemistry. 30: 211-213. PMID 12406705 DOI: 10.1006/bioo.2002.1246  1
2002 Koshland DE, Hamadani K. Proteomics and models for enzyme cooperativity Journal of Biological Chemistry. 277: 46841-46844. PMID 12189158 DOI: 10.1074/jbc.R200014200  1
2002 Radisky ES, Koshland DE. A clogged gutter mechanism for protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 99: 10316-21. PMID 12142461 DOI: 10.1073/Pnas.112332899  1
2002 Koshland DE. Special essay. The seven pillars of life. Science (New York, N.Y.). 295: 2215-6. PMID 11910092 DOI: 10.1126/science.1068489  0.01
2002 Koshland DE. Retrospective. Scientist, mentor, colleague, and friend--Eleanore Butz (1909-2002) Science. 295: 1463. PMID 11859177 DOI: 10.1126/Science.295.5559.1463  1
2002 Charter NW, Mahal LK, Koshland DE, Bertozzi CR. Differential effects of unnatural sialic acids on the polysialylation of the neural cell adhesion molecule and neuronal behavior. The Journal of Biological Chemistry. 277: 9255-61. PMID 11786551 DOI: 10.1074/Jbc.M111619200  1
2002 Koshland DE. Case of the hidden assumptions Biochemistry and Molecular Biology Education. 30: 27-29. DOI: 10.1002/bmb.2002.494030010021  1
2001 Mahal LK, Charter NW, Angata K, Fukuda M, Koshland DE, Bertozzi CR. A small-molecule modulator of poly-alpha 2,8-sialic acid expression on cultured neurons and tumor cells. Science (New York, N.Y.). 294: 380-1. PMID 11598302 DOI: 10.1126/Science.1062192  1
2001 Yu EW, Koshland DE. Propagating conformational changes over long (and short) distances in proteins. Proceedings of the National Academy of Sciences of the United States of America. 98: 9517-20. PMID 11504940 DOI: 10.1073/pnas.161239298  1
2001 Doyle SA, Beernink PT, Koshland DE. Structural basis for a change in substrate specificity: Crystal structure of S113E isocitrate dehydrogenase in a complex with isopropylmalate, Mg2+, and NADP Biochemistry. 40: 4234-4241. PMID 11284679 DOI: 10.1021/bi002533q  1
2000 Doyle SA, Fung SYF, Koshland DE. Redesigning the substrate specificity of an enzyme: Isocitrate dehydrogenase Biochemistry. 39: 14348-14355. PMID 11087384 DOI: 10.1021/bi001458g  1
2000 Charter NW, Mahal LK, Koshland DE, Bertozzi CR. Biosynthetic incorporation of unnatural sialic acids into polysialic acid on neural cells. Glycobiology. 10: 1049-56. PMID 11030751 DOI: 10.1093/Glycob/10.10.1049  1
2000 Mesecar AD, Koshland DE. Sites of binding and orientation in a four-location model for protein stereospecificity. Iubmb Life. 49: 457-66. PMID 10902579 DOI: 10.1080/152165400410326  1
2000 Mesecar AD, Koshland DE. A new model for protein stereospecificity. Nature. 403: 614-5. PMID 10688187 DOI: 10.1038/35001144  1
2000 Cherbavaz DB, Lee ME, Stroud RM, Koshland DE. Active site water molecules revealed in the 2.1 A resolution structure of a site-directed mutant of isocitrate dehydrogenase. Journal of Molecular Biology. 295: 377-85. PMID 10623532 DOI: 10.1006/Jmbi.1999.3195  1
1999 Jeffery CJ, Koshland DE. The Escherichia coli aspartate receptor: Sequence specificity of a transmembrane helix studied by hydrophobic-biased random mutagenesis Protein Engineering. 12: 863-871. PMID 10556247 DOI: 10.1093/Protein/12.10.863  1
1999 Ottemann KM, Xiao W, Shin YK, Koshland DE. A piston model for transmembrane signaling of the aspartate receptor Science. 285: 1751-1754. PMID 10481014 DOI: 10.1126/Science.285.5434.1751  1
1998 Stoddard BL, Cohen BE, Brubaker M, Mesecar AD, Koshland DE. Millisecond Laue structures of an enzyme-product complex using photocaged substrate analogs. Nature Structural Biology. 5: 891-7. PMID 9783749 DOI: 10.1038/2331  1
1998 Le Moual H, Quang T, Koshland DE. Conformational changes in the cytoplasmic domain of the Escherichia coli aspartate receptor upon adaptive methylation Biochemistry. 37: 14852-14859. PMID 9778360 DOI: 10.1021/bi980343y  1
1998 Koshland DE. Conformational changes: how small is big enough? Nature Medicine. 4: 1112-4. PMID 9771734 DOI: 10.1038/2605  0.01
1998 Koshland DE. The era of pathway quantification Science. 280: 852-853. PMID 9599157 DOI: 10.1126/science.280.5365.852  1
1998 Ottemann KM, Thorgeirsson TE, Kolodziej AF, Shin YK, Koshland DE. Direct measurement of small ligand-induced conformational changes in the aspartate chemoreceptor using EPR Biochemistry. 37: 7062-7069. PMID 9585515 DOI: 10.1021/Bi980305E  1
1998 Chen X, Koshland DE. Probing the structure of the cytoplasmic domain of the aspartate receptor by targeted disulfide cross-linking Biochemistry. 37: 5335. PMID 9548766 DOI: 10.1021/bi9750293  1
1997 Finer-Moore J, Tsutakawa SE, Cherbavaz DB, LaPorte DC, Koshland DE, Stroud RM. Access to phosphorylation in isocitrate dehydrogenase may occur by domain shifting Biochemistry. 36: 13890-13896. PMID 9374867 DOI: 10.1021/Bi9711691  1
1997 Le Moual H, Quang T, Koshland DE. Methylation of the Escherichia coli chemotaxis receptors: Intra- and interdimer mechanisms Biochemistry. 36: 13441-13448. PMID 9341238 DOI: 10.1021/bi9713207  1
1997 Ottemann KM, Koshland DE. Converting a transmembrane receptor to a soluble receptor: Recognition domain to effector domain signaling after excision of the transmembrane domain Proceedings of the National Academy of Sciences of the United States of America. 94: 11201-11204. PMID 9326586 DOI: 10.1073/Pnas.94.21.11201  1
1997 Chen X, Koshland DE. Probing the structure of the cytoplasmic domain of the aspartate receptor by targeted disulfide cross-linking Biochemistry. 36: 11858-11864. PMID 9305978 DOI: 10.1021/bi970911u  1
1997 Cohen BE, Stoddard BL, Koshland DE. Caged NADP and NAD. Synthesis and characterization of functionally distinct caged compounds Biochemistry. 36: 9035-9044. PMID 9220992 DOI: 10.1021/Bi970263E  1
1997 Mesecar AD, Stoddard BL, Koshland DE. Orbital steering in the catalytic power of enzymes: small structural changes with large catalytic consequences. Science (New York, N.Y.). 277: 202-6. PMID 9211842 DOI: 10.1126/Science.277.5323.202  1
1996 Koshland DE. The structural basis of negative cooperativity: Receptors and enzymes Current Opinion in Structural Biology. 6: 757-761. PMID 8994875 DOI: 10.1016/S0959-440X(96)80004-2  1
1996 Kolodziej AF, Tan T, Koshland DE. Producing positive, negative, and no cooperativity by mutations at a single residue located at the subunit interface in the aspartate receptor of Salmonella typhimurium Biochemistry. 35: 14782-14792. PMID 8942640 DOI: 10.1021/bi961481v  1
1996 Biemann HP, Harmer SL, Koshland DE. An aspartate/insulin receptor chimera mitogenically activates fibroblasts Journal of Biological Chemistry. 271: 27927-27930. PMID 8910393 DOI: 10.1074/jbc.271.44.27927  1
1996 Yeh JI, Biemann HP, Privé GG, Pandit J, Koshland DE, Kim SH. High-resolution structures of the ligand binding domain of the wild-type bacterial aspartate receptor Journal of Molecular Biology. 262: 186-201. PMID 8831788 DOI: 10.1006/Jmbi.1996.0507  1
1996 Koshland DE. How to get paid for having fun Annual Review of Biochemistry. 65: 1-13. PMID 8811172 DOI: 10.1146/Annurev.Bi.65.070196.000245  1
1996 Le Moual H, Koshland DE. Molecular evolution of the C-terminal cytoplasmic domain of a superfamily of bacterial receptors involved in taxis Journal of Molecular Biology. 261: 568-585. PMID 8794877 DOI: 10.1006/jmbi.1996.0483  1
1996 Zhang T, Koshland DE. Computational method for relative binding energies of enzyme-substrate complexes Protein Science. 5: 348-356. PMID 8745413 DOI: 10.1002/Pro.5560050219  1
1996 Dean AM, Shiau AK, Koshland DE. Determinants of performance in the isocitrate dehydrogenase of Escherichia coli. Protein Science : a Publication of the Protein Society. 5: 341-7. PMID 8745412 DOI: 10.1002/Pro.5560050218  1
1996 Brubaker MJ, Dyer DH, Stoddard B, Koshland DE. Synthesis, kinetics, and structural studies of a photolabile caged isocitrate: A catalytic trigger for isocitrate dehydrogenase Biochemistry. 35: 2854-2864. PMID 8608121 DOI: 10.1021/Bi951105V  1
1995 Koshland DE. New Year's Resolutions, 1995. Science (New York, N.Y.). 267: 11. PMID 17840040 DOI: 10.1126/science.267.5194.11  0.01
1995 Koshland DE. The importance of intelligence. Science (New York, N.Y.). 267: 311. PMID 17837470 DOI: 10.1126/science.267.5196.311  0.01
1995 Koshland DE. Science in latin america. Science (New York, N.Y.). 267: 771. PMID 17813881 DOI: 10.1126/science.267.5199.771  0.01
1995 Koshland DE. The opportunity connection. Science (New York, N.Y.). 267: 1075. PMID 17789178 DOI: 10.1126/science.267.5201.1075  0.01
1995 Koshland DE. Noitall seeks new horizons. Science (New York, N.Y.). 268: 479. PMID 17756701 DOI: 10.1126/science.268.5210.479  0.01
1995 Koshland DE. SOSS: Save Our Social Security. Science (New York, N.Y.). 267: 599. PMID 17745821 DOI: 10.1126/science.267.5198.599  0.01
1995 Koshland DE. Letter to Floyd Bloom, Editor-in-Chief-Elect. Science (New York, N.Y.). 267: 1403. PMID 17743526 DOI: 10.1126/science.267.5203.1403  0.01
1995 Koshland DE. The crystal ball and the trumpet call Science. 267: 1575. PMID 7886434  1
1995 Shapiro MJ, Chakrabarti I, Koshland DE. Contributions made by individual methylation sites of the Escherichia coli aspartate receptor to chemotactic behavior Proceedings of the National Academy of Sciences of the United States of America. 92: 1053-1056. PMID 7862632 DOI: 10.1073/pnas.92.4.1053  1
1995 Shapiro MJ, Panomitros D, Koshland DE. Interactions between the methylation sites of the Escherichia coli aspartate receptor mediated by the methyltransferase Journal of Biological Chemistry. 270: 751-755. PMID 7822306 DOI: 10.1074/jbc.270.2.751  1
1995 Koshland DE. Mutational analysis of the catalytic residues lysine 230 and tyrosine 160 in the NADP+-dependent isocitrate dehydrogenase from escherichia coli Biochemistry®. 34: 378-384. PMID 7819221 DOI: 10.1021/Bi00001A046  1
1995 Zhang T, Koshland DE. Modeling substrate binding in Thermus thermophilus isopropylmalate dehydrogenase Protein Science. 4: 84-92. PMID 7773180 DOI: 10.1002/Pro.5560040111  1
1995 Bolduc JM, Dyer DH, Scott WG, Singer P, Sweet RM, Koshland DE, Stoddard BL. Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase. Science (New York, N.Y.). 268: 1312-8. PMID 7761851 DOI: 10.1126/Science.7761851  1
1995 Martin PT, Koshland DE. Neurosecretory habilitation in PC12 cells: Modulation during parallel habituation Proceedings of the National Academy of Sciences of the United States of America. 92: 5052-5056. PMID 7761447 DOI: 10.1073/Pnas.92.11.5052  1
1995 Koshland DE. The pharmacia biotech & science prize Science. 268: 347. PMID 7716528 DOI: 10.1126/Science.7716528  1
1995 Tsutakawa SE, Medzihradszky KF, Flint AJ, Burlingame AL, Koshland DE. Determination of in vivo phosphorylation sites in protein kinase C Journal of Biological Chemistry. 270: 26807-26812. PMID 7592921 DOI: 10.1074/Jbc.270.45.26807  1
1995 Chen X, Koshland DE. The N-terminal cytoplasmic tail of the aspartate receptor is not essential in signal transduction of bacterial chemotaxis Journal of Biological Chemistry. 270: 24038-24042. PMID 7592602 DOI: 10.1074/jbc.270.41.24038  1
1994 Koshland DE. The perversity of inanimate objects. Science (New York, N.Y.). 263: 155. PMID 17839158 DOI: 10.1126/science.263.5144.155  0.01
1994 Koshland DE. Progress in Japanese science. Science (New York, N.Y.). 266: 1139. PMID 17810241 DOI: 10.1126/science.266.5188.1139  0.01
1994 Koshland DE. Careers in science. Science (New York, N.Y.). 265: 1787. PMID 17797199 DOI: 10.1126/science.265.5180.1787  0.01
1994 Koshland DE. Response. Science (New York, N.Y.). 266: 528. PMID 17793439 DOI: 10.1126/science.266.5185.528-a  0.01
1994 Norman C, Koshland DE. Science in Russia. Science (New York, N.Y.). 264: 1235. PMID 17780817 DOI: 10.1126/Science.264.5163.1235  0.04
1994 Koshland DE. A milk-free zone. Science (New York, N.Y.). 264: 11. PMID 17778111 DOI: 10.1126/science.264.5155.11  0.01
1994 Koshland DE. Women in science. Science (New York, N.Y.). 263: 1355. PMID 17776494 DOI: 10.1126/science.263.5152.1355  0.01
1994 Koshland DE. Response. Science (New York, N.Y.). 266: 202-3. PMID 17771431 DOI: 10.1126/science.266.5183.202  0.01
1994 Koshland DE. The time traveler. Science (New York, N.Y.). 265: 1639. PMID 17770875 DOI: 10.1126/science.265.5179.1639  0.01
1994 Koshland DE. The path to research prioritization. Science (New York, N.Y.). 263: 735. PMID 17770817 DOI: 10.1126/science.263.5148.735  0.01
1994 Koshland DE. A simple proposal for health care rationing. Science (New York, N.Y.). 264: 1515. PMID 17769583 DOI: 10.1126/science.264.5165.1515  0.01
1994 Koshland DE, Hanson B. Earthquakes and collective action. Science (New York, N.Y.). 263: 451. PMID 17754867 DOI: 10.1126/science.263.5146.451  0.01
1994 Koshland DE. Paradise gained. Science (New York, N.Y.). 265: 167. PMID 17750639 DOI: 10.1126/science.265.5169.167  0.01
1994 Koshland DE. The case for diversity. Science (New York, N.Y.). 264: 639. PMID 17737928 DOI: 10.1126/science.264.5159.639  0.01
1994 Koshland DE. Scientific evidence in court. Science (New York, N.Y.). 266: 1787. PMID 17737056 DOI: 10.1126/science.266.5192.1787  0.01
1994 Koshland DE. Educating the best and employing them. Science (New York, N.Y.). 266: 711. PMID 17730377 DOI: 10.1126/science.266.5186.711  0.01
1994 Morimoto BH, Koshland DE. Conditional activation of cAMP signal transduction by protein kinase C. The effect of phorbol esters on adenylyl cyclase in permeabilized and intact cells. The Journal of Biological Chemistry. 269: 4065-9. PMID 8307964  1
1994 Biemann HP, Koshland DE. Aspartate receptors of Escherichia coli and Salmonella typhimurium bind ligand with negative and half-of-the-sites cooperativity Biochemistry. 33: 629-634. PMID 8292590 DOI: 10.1021/Bi00169A002  1
1994 Koshland DE. Research in the service of jobs and health Science. 264: 887. PMID 8178141 DOI: 10.1126/Science.8178141  1
1994 Shapiro MJ, Koshland DE. Mutagenic studies of the interaction between the aspartate receptor and methyltransferase from Escherichia coli Journal of Biological Chemistry. 269: 11054-11059. PMID 8157631  1
1994 Koshland DE. The biological warfare of the future Science. 264: 327. PMID 8153609 DOI: 10.1126/Science.8153609  1
1994 Koshland DE. A single hydrophobic to hydrophobic substitution in the transmembrane domain impairs aspartate receptor function Biochemistry. 33: 3457-3463. PMID 8142342 DOI: 10.1021/Bi00178A001  1
1994 Koshland DE. Strategic goals on an NIH model Science. 263: 1071. PMID 8108720 DOI: 10.1126/Science.8108720  1
1994 Koshland DE. Kaposi's sarcoma, vascular permeability, and scientific integrity. Jama. 272: 921-2. PMID 8084057  0.01
1994 Kiberstis PA, Benditt JM, Koshland DE. Vaccines: A study in contrasts Science. 265: 1343. PMID 8073265 DOI: 10.1126/Science.8073265  1
1994 Koshland DE. The DNA fingerprint story (continued) Science. 265: 1015. PMID 8066435 DOI: 10.1126/Science.8066435  1
1994 Cheever L, Koshland DE. Habituation of neurosecretory responses to extracellular ATP in PC12 cells Journal of Neuroscience. 14: 4831-4838. PMID 8046454 DOI: 10.1523/Jneurosci.14-08-04831.1994  1
1994 Koshland DE. The spousal abuse problem Science. 265: 455. PMID 8036485 DOI: 10.1126/Science.8036485  1
1994 Koshland DE. Ahead of schedule and on budget Science. 266: 199. PMID 7939646 DOI: 10.1126/Science.7939646  1
1994 Danielson MA, Biemann HP, Koshland DE, Falke JJ. Attractant- and disulfide-induced conformational changes in the ligand binding domain of the chemotaxis aspartate receptor: A19F NMR study Biochemistry. 33: 6100-6109. PMID 7910759 DOI: 10.1021/Bi00186A009  1
1994 Culotta E, Koshland DE. DNA repair works its way to the top Science. 266: 1926-1929. PMID 7801115 DOI: 10.1126/SCIENCE.7801115  1
1994 Koshland DE. Molecule of the year: The DNA repair enzyme Science. 266: 1925. PMID 7801114 DOI: 10.1126/Science.7801114  1
1993 Voss DF, Koshland DE. The lessons of the super collider. Science (New York, N.Y.). 262: 1799. PMID 17829609 DOI: 10.1126/science.262.5141.1799  0.04
1993 Koshland DE. Science in Asia. Science (New York, N.Y.). 262: 315. PMID 17789901 DOI: 10.1126/science.262.5132.315  0.01
1993 Koshland DE. Minorities in science. Science (New York, N.Y.). 262: 971. PMID 17782030 DOI: 10.1126/science.262.5136.971  0.01
1993 Yeh JI, Biemann HP, Pandit J, Koshland DE, Kim SH. The three-dimensional structure of the ligand-binding domain of a wild-type bacterial chemotaxis receptor: Structural comparison to the cross-linked mutant forms and conformational changes upon ligand binding Journal of Biological Chemistry. 268: 9787-9792. PMID 8486661 DOI: 10.2210/Pdb1Was/Pdb  1
1993 Koshland DE. Moderation in science budgeting Science. 260: 603. PMID 8480167 DOI: 10.1126/science.8480167  1
1993 Koshland DE. Basic research (III): Priorities Science. 259: 1379. PMID 8451629 DOI: 10.1126/SCIENCE.8451629  1
1993 Stoddard BL, Koshland DE. Molecular recognition analyzed by docking simulations: The aspartate receptor and isocitrate dehydrogenase from Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 90: 1146-1153. PMID 8433976 DOI: 10.1073/Pnas.90.4.1146  1
1993 Jeffery CJ, Koshland DE. Vibrio cholerae hlyB is a member of the chemotaxis receptor gene family. Protein Science : a Publication of the Protein Society. 2: 1532-5. PMID 8401237 DOI: 10.1002/Pro.5560020918  1
1993 Koshland DE. The joys and vicissitudes of protein science. Protein Science : a Publication of the Protein Society. 2: 1364-8. PMID 8401222 DOI: 10.1002/pro.5560020821  0.01
1993 Milligan DL, Koshland DE. Purification and characterization of the periplasmic domain of the aspartate chemoreceptor Journal of Biological Chemistry. 268: 19991-19997. PMID 8397194  1
1993 Jeffery CJ, Koshland DE. Three-dimensional structural model of the serine receptor ligand-binding domain. Protein Science : a Publication of the Protein Society. 2: 559-66. PMID 8390884 DOI: 10.1002/Pro.5560020407  1
1993 Stoddard BL, Koshland DE. Structure of isocitrate dehydrogenase with α-ketoglutarate at 2.7-å resolution: conformational changes induced by decarboxylation of isocitrate Biochemistry®. 32: 9317-9322. PMID 8369301 DOI: 10.1021/Bi00087A009  1
1993 Stoddard BL, Dean A, Koshland DE. Structure of isocitrate dehydrogenase with isocitrate, nicotinamide adenine dinucleotide phosphate, and calcium at 2.5-å resolution: a pseudo-michaelis ternary complex Biochemistry®. 32: 9310-9316. PMID 8369300 DOI: 10.1021/Bi00087A008  1
1993 Dean AM, Koshland DE. Kinetic mechanism of Escherichia coli isocitrate dehydrogenase. Biochemistry. 32: 9302-9. PMID 8369299 DOI: 10.1021/Bi00087A007  1
1993 Koshland DE. Three good choices Science. 261: 1099. PMID 8356440 DOI: 10.1126/science.8356440  1
1993 Scott WG, Milligan DL, Milburn MV, Privé GG, Yeh J, Koshland DE, Kim SH. Refined structures of the ligand-binding domain of the aspartate receptor from Salmonella typhimurium Journal of Molecular Biology. 232: 555-573. PMID 8345523 DOI: 10.1006/Jmbi.1993.1411  1
1993 Koshland DE. Molecule of the year. Science (New York, N.Y.). 262: 1953. PMID 8266084 DOI: 10.1126/Science.8266084  0.01
1993 Koshland DE. Health care: More access and more cures Science. 262: 1495. PMID 8248788 DOI: 10.1126/Science.8248788  1
1993 Koshland DE. Frontiers in neuroscience. Science (New York, N.Y.). 262: 635. PMID 8235575 DOI: 10.1126/Science.3187505  0.01
1993 Martin PT, Chung BT, Koshland DE. Regulation of neurosecretory habituation by cAMP. Role of adaptation of cAMP signals. European Journal of Biochemistry. 217: 259-65. PMID 8223563 DOI: 10.1111/J.1432-1033.1993.Tb18241.X  1
1993 Koshland DE. The two-component pathway comes to eukaryotes. Science (New York, N.Y.). 262: 532. PMID 8211179 DOI: 10.1126/Science.8211179  0.01
1993 Culotta E, Koshland DE. p53 sweeps through cancer research. Science (New York, N.Y.). 262: 1958-61. PMID 7903477 DOI: 10.1126/Science.7903477  1
1992 Stoddard BL, Bui JD, Koshland DE. Structure and dynamics of transmembrane signaling by the Escherichia coli aspartate receptor. Biochemistry. 31: 11978-83. PMID 1457398 DOI: 10.1021/Bi00163A004  1
1992 Cheever L, Koshland DE. Retention of habituation in PC12 cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 10084-8. PMID 1438197 DOI: 10.1073/Pnas.89.21.10084  1
1992 McFadden PN, Koshland DE. The biochemistry of the neuron: Methods and calculations for the analysis of neurotransmitter secretion from populations of single cells Analytical Biochemistry. 201: 52-61. PMID 1352437 DOI: 10.1016/0003-2697(92)90173-5  1
1992 Stoddard BL, Biemann HP, Koshland DE. Receptors and transmembrane signaling Cold Spring Harbor Symposia On Quantitative Biology. 57: 1-16. PMID 1339648 DOI: 10.1101/Sqb.1992.057.01.003  1
1992 Martin PT, Koshland DE. Regulation of neurosecretory habituation in PC12 cells: parallel pathways used by cAMP and calcium. Proceedings of the National Academy of Sciences of the United States of America. 89: 10257-61. PMID 1332039 DOI: 10.1073/Pnas.89.21.10257  1
1992 Stoddard BL, Koshland DE. Prediction of the structure of a receptor-protein complex using a binary docking method Nature. 358: 774-776. PMID 1324436 DOI: 10.1038/358774A0  1
1992 Lynch BA, Koshland DE. The fifth Datta Lecture. Structural similarities between the aspartate receptor of bacterial chemotaxis and the trp repressor of E. coli. Implications for transmembrane signaling. Febs Letters. 307: 3-9. PMID 1322324 DOI: 10.1016/0014-5793(92)80891-J  1
1992 Sanders DA, Gillece-Castro BL, Burlingame AL, Koshland DE. Phosphorylation site of NtrC, a protein phosphatase whose covalent intermediate activates transcription Journal of Bacteriology. 174: 5117-5122. PMID 1321122 DOI: 10.1128/Jb.174.15.5117-5122.1992  1
1991 Martin PT, Koshland DE. The biochemistry of the neuron. Neurosecretory habituation to repetitive depolarizations in PC12 cells. The Journal of Biological Chemistry. 266: 7388-92. PMID 2019575  1
1991 Morimoto BH, Koshland DE. Short-term and long-term memory in single cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 2061-7. PMID 2010059 DOI: 10.1096/fasebj.5.7.2010059  1
1991 Hurley JH, Dean AM, Koshland DE, Stroud RM. Catalytic mechanism of NADP(+)-dependent isocitrate dehydrogenase: implications from the structures of magnesium-isocitrate and NADP+ complexes. Biochemistry. 30: 8671-8. PMID 1888729 DOI: 10.1021/Bi00099A026  1
1991 Dunten P, Koshland DE. Tuning the responsiveness of a sensory receptor via covalent modification. The Journal of Biological Chemistry. 266: 1491-6. PMID 1846357  0.12
1991 Morimoto BH, Chuang CC, Koshland DE. Molecular cloning of a member of a new class of low-molecular-weight GTP-binding proteins. Genes & Development. 5: 2386-91. PMID 1752434 DOI: 10.1101/Gad.5.12B.2386  1
1991 Milligan DL, Koshland DE. Intrasubunit signal transduction by the aspartate chemoreceptor Science. 254: 1651-1654. PMID 1661030 DOI: 10.1126/Science.1661030  1
1991 Milburn MV, Privé GG, Milligan DL, Scott WG, Yeh J, Jancarik J, Koshland DE, Kim SH. Three-dimensional structures of the ligand-binding domain of the bacterial aspartate receptor with and without a ligand Science. 254: 1342-1347. PMID 1660187 DOI: 10.1126/Science.1660187  1
1991 Morimoto BH, Koshland DE. Identification of cyclic AMP as the response regulator for neurosecretory potentiation: a memory model system. Proceedings of the National Academy of Sciences of the United States of America. 88: 10835-9. PMID 1660152 DOI: 10.1073/Pnas.88.23.10835  1
1991 Lynch BA, Koshland DE. Disulfide cross-linking studies of the transmembrane regions of the aspartate sensory receptor of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 88: 10402-6. PMID 1660136 DOI: 10.1073/Pnas.88.23.10402  1
1991 Jancarik J, Scott WG, Milligan DL, Koshland DE, Kim SH. Crystallization and preliminary X-ray diffraction study of the ligand-binding domain of the bacterial chemotaxis-mediating aspartate receptor of Salmonella typhimurium Journal of Molecular Biology. 221: 31-34. PMID 1656050 DOI: 10.1016/0022-2836(91)80198-4  1
1990 Hurley JH, Dean AM, Thorsness PE, Koshland DE, Stroud RM. Regulation of isocitrate dehydrogenase by phosphorylation involves no long-range conformational change in the free enzyme. The Journal of Biological Chemistry. 265: 3599-602. PMID 2406256 DOI: 10.2210/Pdb4Icd/Pdb  1
1990 Weis RM, Koshland DE. Chemotaxis in Escherichia coli proceeds efficiently from different initial tumble frequencies. Journal of Bacteriology. 172: 1099-105. PMID 2404936 DOI: 10.1128/Jb.172.2.1099-1105.1990  1
1990 Newton AC, Koshland DE. Phosphatidylserine affects specificity of protein kinase C substrate phosphorylation and autophosphorylation. Biochemistry. 29: 6656-61. PMID 2397206 DOI: 10.1021/Bi00480A015  1
1990 Flint AJ, Paladini RD, Koshland DE. Autophosphorylation of protein kinase C at three separated regions of its primary sequence. Science (New York, N.Y.). 249: 408-11. PMID 2377895 DOI: 10.1126/Science.2377895  1
1990 McFadden PN, Koshland DE. Parallel pathways for habituation in repetitively stimulated PC12 cells Neuron. 4: 615-621. PMID 2322464 DOI: 10.1016/0896-6273(90)90119-Z  1
1990 McFadden PN, Koshland DE. Habituation in the single cell: Diminished secretion of norepinephrine with repetitive depolarization of PC12 cells Proceedings of the National Academy of Sciences of the United States of America. 87: 2031-2035. PMID 2308963 DOI: 10.1073/Pnas.87.5.2031  1
1990 Dean AM, Koshland DE. Electrostatic and steric contributions to regulation at the active site of isocitrate dehydrogenase. Science (New York, N.Y.). 249: 1044-6. PMID 2204110 DOI: 10.1126/Science.2204110  1
1990 Hurley JH, Dean AM, Sohl JL, Koshland DE, Stroud RM. Regulation of an enzyme by phosphorylation at the active site. Science (New York, N.Y.). 249: 1012-6. PMID 2204109 DOI: 10.1126/Science.2204109  1
1990 Weis RM, Chasalow S, Koshland DE. The role of methylation in chemotaxis. An explanation of outstanding anomalies. The Journal of Biological Chemistry. 265: 6817-26. PMID 2182629  1
1990 Milligan DL, Koshland DE. The amino terminus of the aspartate chemoreceptor is formylmethionine Journal of Biological Chemistry. 265: 4455-4460. PMID 2155229  1
1990 Morimoto BH, Koshland DE. Induction and expression of long- and short-term neurosecretory potentiation in a neural cell line. Neuron. 5: 875-80. PMID 1980069 DOI: 10.1016/0896-6273(90)90347-I  1
1990 Morimoto BH, Koshland DE. Excitatory amino acid uptake and N-methyl-D-aspartate-mediated secretion in a neural cell line. Proceedings of the National Academy of Sciences of the United States of America. 87: 3518-21. PMID 1970639 DOI: 10.1073/pnas.87.9.3518  1
1989 Koshland DE. The process of publication. Science (New York, N.Y.). 245: 573. PMID 11644383 DOI: 10.1126/Science.11644383  0.01
1989 Koshland DE. The engineering of species. Science (New York, N.Y.). 244: 1233. PMID 11644373 DOI: 10.1126/Science.11644373  0.01
1989 Newton AC, Koshland DE. High cooperativity, specificity, and multiplicity in the protein kinase C-lipid interaction. The Journal of Biological Chemistry. 264: 14909-15. PMID 2768246  1
1989 McFadden PN, Mandpe A, Koshland DE. Calcium- and lipid-independent protein kinase C autophosphorylation. Activation by low pH Journal of Biological Chemistry. 264: 12765-12771. PMID 2753884  1
1989 Sanders DA, Gillece-Castro BL, Stock AM, Burlingame AL, Koshland DE. Identification of the site of phosphorylation of the chemotaxis response regulator protein, CheY Journal of Biological Chemistry. 264: 21770-21778. PMID 2689446  1
1989 Hurley JH, Thorsness PE, Ramalingam V, Helmers NH, Koshland DE, Stroud RM. Structure of a bacterial enzyme regulated by phosphorylation, isocitrate dehydrogenase Proceedings of the National Academy of Sciences of the United States of America. 86: 8635-8639. PMID 2682654 DOI: 10.1073/Pnas.86.22.8635  1
1989 Kuo SC, Koshland DE. Multiple kinetic states for the flagellar motor switch Journal of Bacteriology. 171: 6279-6287. PMID 2681161 DOI: 10.1128/Jb.171.11.6279-6287.1989  1
1989 Sanders DA, Mendez B, Koshland DE. Role of the CheW protein in bacterial chemotaxis: overexpression is equivalent to absence. Journal of Bacteriology. 171: 6271-8. PMID 2681160 DOI: 10.1128/Jb.171.11.6271-6278.1989  1
1989 Moe GR, Bollag GE, Koshland DE. Transmembrane signaling by a chimera of the Escherichia coli aspartate receptor and the human insulin receptor. Proceedings of the National Academy of Sciences of the United States of America. 86: 5683-7. PMID 2548185 DOI: 10.1073/Pnas.86.15.5683  1
1989 Dean AM, Lee MH, Koshland DE. Phosphorylation inactivates Escherichia coli isocitrate dehydrogenase by preventing isocitrate binding. The Journal of Biological Chemistry. 264: 20482-6. PMID 2511204  1
1988 Koshland DE. Science, journalism, and whistle-blowing. Science (New York, N.Y.). 240: 585. PMID 11644303 DOI: 10.1126/Science.11644303  0.01
1988 Mochly-Rosen D, Koshland DE. A general procedure for screening inhibitory antibodies: application for identifying anti-protein kinase C antibodies. Analytical Biochemistry. 170: 31-7. PMID 3291639 DOI: 10.1016/0003-2697(88)90085-1  0.04
1988 Koshland DE, Sanders DA, Weis RM. Roles of methylation and phosphorylation in the bacterial sensing system. Cold Spring Harbor Symposia On Quantitative Biology. 53: 11-7. PMID 3076076 DOI: 10.1101/Sqb.1988.053.01.004  1
1988 Koshland DE. Chemotaxis as a model second-messenger system. Biochemistry. 27: 5829-34. PMID 3056514 DOI: 10.1021/Bi00416A001  0.01
1988 Falke JJ, Dernburg AF, Sternberg DA, Zalkin N, Milligan DL, Koshland DE. Structure of a bacterial sensory receptor. A site-directed sulfhydryl study. The Journal of Biological Chemistry. 263: 14850-8. PMID 3049592  1
1988 Sanders DA, Koshland DE. Receptor interactions through phosphorylation and methylation pathways in bacterial chemotaxis Proceedings of the National Academy of Sciences of the United States of America. 85: 8425-8429. PMID 2847160 DOI: 10.1073/Pnas.85.22.8425  1
1988 Milligan DL, Koshland DE. Site-directed cross-linking. Establishing the dimeric structure of the aspartate receptor of bacterial chemotaxis Journal of Biological Chemistry. 263: 6268-6275. PMID 2834370  1
1988 Weis RM, Koshland DE. Reversible receptor methylation is essential for normal chemotaxis of Escherichia coli in gradients of aspartic acid. Proceedings of the National Academy of Sciences of the United States of America. 85: 83-7. PMID 2829179 DOI: 10.1073/Pnas.85.1.83  1
1987 Newton AC, Koshland DE. Protein kinase C autophosphorylates by an intrapeptide reaction. The Journal of Biological Chemistry. 262: 10185-8. PMID 3611058  1
1987 Kuo SC, Koshland DE. Roles of cheY and cheZ gene products in controlling flagellar rotation in bacterial chemotaxis of Escherichia coli Journal of Bacteriology. 169: 1307-1314. PMID 3546269 DOI: 10.1128/Jb.169.3.1307-1314.1987  1
1987 Walsh K, Schena M, Flint AJ, Koshland DE. Compensatory regulation in metabolic pathways--responses to increases and decreases in citrate synthase levels. Biochemical Society Symposium. 54: 183-95. PMID 3332995  1
1987 Mochly-Rosen D, Basbaum AI, Koshland DE. Distinct cellular and regional localization of immunoreactive protein kinase C in rat brain. Proceedings of the National Academy of Sciences of the United States of America. 84: 4660-4. PMID 3299372 DOI: 10.1073/Pnas.84.13.4660  1
1987 Stock A, Schaeffer E, Koshland DE, Stock J. A second type of protein methylation reaction in bacterial chemotaxis. The Journal of Biological Chemistry. 262: 8011-4. PMID 3298225  1
1987 Mowbray SL, Koshland DE. Additive and independent responses in a single receptor: aspartate and maltose stimuli on the tar protein. Cell. 50: 171-80. PMID 3297352 DOI: 10.1016/0092-8674(87)90213-3  1
1987 Baudier J, Mochly-Rosen D, Newton A, Lee SH, Koshland DE, Cole RD. Comparison of S100b protein with calmodulin: interactions with melittin and microtubule-associated tau proteins and inhibition of phosphorylation of tau proteins by protein kinase C. Biochemistry. 26: 2886-93. PMID 3111527 DOI: 10.1021/Bi00384A033  1
1987 Thorsness PE, Mowbray SL, Koshland DE. Transmission of regulatory conformational changes through proteins Cold Spring Harbor Symposia On Quantitative Biology. 52: 623-630. PMID 2841071 DOI: 10.1101/Sqb.1987.052.01.071  1
1987 Falke JJ, Koshland DE. Global flexibility in a sensory receptor: a site-directed cross-linking approach. Science (New York, N.Y.). 237: 1596-600. PMID 2820061 DOI: 10.1126/Science.2820061  1
1987 Koshland DE. Evolution of catalytic function. Cold Spring Harbor Symposia On Quantitative Biology. 52: 1-7. PMID 2456872 DOI: 10.1101/Sqb.1987.052.01.003  0.01
1986 Kuo SC, Koshland DE. Sequence of the flaA (cheC) locus of Escherichia coli and discovery of a new gene. Journal of Bacteriology. 166: 1007-12. PMID 3519573 DOI: 10.1128/Jb.166.3.1007-1012.1986  1
1986 Terwilliger TC, Bollag GE, Sternberg DW, Koshland DE. S-methyl glutathione synthesis is catalyzed by the cheR methyltransferase in Escherichia coli. Journal of Bacteriology. 165: 958-63. PMID 3512532 DOI: 10.1128/Jb.165.3.958-963.1986  1
1986 Ellis L, Morgan DO, Koshland DE, Clauser E, Moe GR, Bollag G, Roth RA, Rutter WJ. Linking functional domains of the human insulin receptor with the bacterial aspartate receptor Proceedings of the National Academy of Sciences of the United States of America. 83: 8137-8141. PMID 3022282 DOI: 10.1073/pnas.83.21.8137  1
1986 Terwilliger TC, Wang JY, Koshland DE. Kinetics of receptor modification. The multiply methylated aspartate receptors involved in bacterial chemotaxis. The Journal of Biological Chemistry. 261: 10814-20. PMID 3015942  1
1986 Russo AF, Koshland DE. Identification of the tip-encoded receptor in bacterial sensing. Journal of Bacteriology. 165: 276-82. PMID 3001027 DOI: 10.1128/Jb.165.1.276-282.1986  1
1986 Terwilliger TC, Wang JY, Koshland DE. Surface structure recognized for covalent modification of the aspartate receptor in chemotaxis. Proceedings of the National Academy of Sciences of the United States of America. 83: 6707-10. PMID 2875460 DOI: 10.1073/Pnas.83.18.6707  1
1985 Stock J, Kersulis G, Koshland DE. Neither methylating nor demethylating enzymes are required for bacterial chemotaxis. Cell. 42: 683-90. PMID 3928170 DOI: 10.1016/0092-8674(85)90125-4  1
1985 Bogonez E, Koshland DE. Solubilization of a vectorial transmembrane receptor in functional form: aspartate receptor of chemotaxis. Proceedings of the National Academy of Sciences of the United States of America. 82: 4891-5. PMID 3895226 DOI: 10.1073/Pnas.82.15.4891  1
1985 Walsh K, Koshland DE. Characterization of rate-controlling steps in vivo by use of an adjustable expression vector. Proceedings of the National Academy of Sciences of the United States of America. 82: 3577-81. PMID 3889909  1
1985 Koshland DE, Walsh K, LaPorte DC. Sensitivity of metabolic fluxes to covalent control Current Topics in Cellular Regulation. 27: 13-22. PMID 3004815 DOI: 10.1016/B978-0-12-152827-0.50009-8  1
1985 Stock A, Koshland DE, Stock J. Homologies between the Salmonella typhimurium CheY protein and proteins involved in the regulation of chemotaxis, membrane protein synthesis, and sporulation. Proceedings of the National Academy of Sciences of the United States of America. 82: 7989-93. PMID 2999789 DOI: 10.1073/Pnas.82.23.7989  1
1985 Mowbray SL, Foster DL, Koshland DE. Proteolytic fragments identified with domains of the aspartate chemoreceptor Journal of Biological Chemistry. 260: 11711-11718. PMID 2995347  1
1985 Foster DL, Mowbray SL, Jap BK, Koshland DE. Purification and characterization of the aspartate chemoreceptor Journal of Biological Chemistry. 260: 11706-11710. PMID 2995346  1
1985 Clegg DO, Koshland DE. Identification of a bacterial sensing protein and effects of its elevated expression Journal of Bacteriology. 162: 398-405. PMID 2984180 DOI: 10.1128/Jb.162.1.398-405.1985  1
1985 Walsh K, Koshland DE. Branch point control by the phosphorylation state of isocitrate dehydrogenase. A quantitative examination of fluxes during a regulatory transition. The Journal of Biological Chemistry. 260: 8430-7. PMID 2861202  1
1984 LaPorte DC, Walsh K, Koshland DE. The branch point effect. Ultrasensitivity and subsensitivity to metabolic control Journal of Biological Chemistry. 259: 14068-14075. PMID 6389540  1
1984 Snyder MA, Stock JB, Koshland DE. Carboxylmethyl esterase of bacterial chemotaxis. Methods in Enzymology. 106: 321-30. PMID 6387376 DOI: 10.1016/0076-6879(84)06032-8  1
1984 Stock JB, Clarke S, Koshland DE. The protein carboxylmethyltransferase involved in Escherichia coli and Salmonella typhimurium chemotaxis. Methods in Enzymology. 106: 310-21. PMID 6387375 DOI: 10.1016/0076-6879(84)06031-6  1
1984 Walsh K, Koshland DE. Determination of flux through the branch point of two metabolic cycles. The tricarboxylic acid cycle and the glyoxylate shunt. The Journal of Biological Chemistry. 259: 9646-54. PMID 6378912  1
1984 Terwilliger TC, Koshland DE. Sites of methyl esterification and deamination on the aspartate receptor involved in chemotaxis. The Journal of Biological Chemistry. 259: 7719-25. PMID 6330075  1
1984 Clegg DO, Koshland DE. The role of a signaling protein in bacterial sensing: Behavioral effects of increased gene expression Proceedings of the National Academy of Sciences of the United States of America. 81: 5056-5060. PMID 6089173 DOI: 10.1073/Pnas.81.16.5056  1
1984 Stock J, Koshland DE. Sensory Adaptation Mechanisms in Swarm Development Cold Spring Harbor Monograph Archive. 16: 117-131. DOI: 10.1101/087969172.16.117  1
1984 Snyder MA, Stock JB, Koshland DE. [30] Carboxymethyl esterase of bacterial chemotaxis Methods in Enzymology. 106: 321-330. DOI: 10.1016/0076-6879(84)06032-8  1
1984 Stock JB, Clarke S, Koshland DE. [29] The protein carboxylmethyltransferase involved in Escherichia coli and Salmonella typhimurium chemotaxis Methods in Enzymology. 106: 310-321. DOI: 10.1016/0076-6879(84)06031-6  1
1983 Wang JY, Koshland DE. The reversible phosphorylation of isocitrate dehydrogenase of Salmonella typhimurium. Archives of Biochemistry and Biophysics. 218: 59-67. PMID 6756316 DOI: 10.1016/0003-9861(82)90321-6  0.44
1983 Laporte DC, Koshland DE. Phosphorylation of isocitrate dehydrogenase as a demonstration of enhanced sensitivity in covalent regulation Nature. 305: 286-290. PMID 6312317 DOI: 10.1038/305286A0  1
1983 Terwilliger TC, Bogonez E, Wang EA, Koshland DE. Sites of methyl esterification on the aspartate receptor involved in bacterial chemotaxis. The Journal of Biological Chemistry. 258: 9608-11. PMID 6309776  1
1983 Gutterson NI, Koshland DE. Replacement and amplification of bacterial genes with sequences altered in vitro. Proceedings of the National Academy of Sciences of the United States of America. 80: 4894-8. PMID 6308658  0.16
1983 Russo AF, Koshland DE. Separation of signal transduction and adaptation functions of the aspartate receptor in bacterial sensing. Science (New York, N.Y.). 220: 1016-20. PMID 6302843 DOI: 10.1126/Science.6302843  1
1982 Goldbeter A, Koshland DE. Simple molecular model for sensing and adaptation based on receptor modification with application to bacterial chemotaxis Journal of Molecular Biology. 161: 395-416. PMID 7154085 DOI: 10.1016/0022-2836(82)90246-7  1
1982 Koshland DE, Goldbeter A, Stock JB. Amplification and adaptation in regulatory and sensory systems. Science (New York, N.Y.). 217: 220-5. PMID 7089556 DOI: 10.1126/Science.7089556  1
1982 Goldbeter A, Koshland DE. Sensitivity amplification in biochemical systems Quarterly Reviews of Biophysics. 15: 555-591. PMID 6294720 DOI: 10.1017/S0033583500003449  1
1982 Laporte DC, Koshland DE. A protein with kinase and phosphatase activities involved in regulation of tricarboxylic acid cycle Nature. 300: 458-460. PMID 6292732 DOI: 10.1038/300458A0  1
1982 DeFranco AL, Koshland DE. Construction and behavior of strains with mutations in two chemotaxis genes. Journal of Bacteriology. 150: 1297-301. PMID 6281242  1
1982 Wang EA, Mowry KL, Clegg DO, Koshland DE. Tandem duplication and multiple functions of a receptor gene in bacterial chemotaxis. The Journal of Biological Chemistry. 257: 4673-6. PMID 6279644  1
1981 Stock JB, Maderis AM, Koshland DE. Bacterial chemotaxis in the absence of receptor carboxylmethylation. Cell. 27: 37-44. PMID 7034965 DOI: 10.1016/0092-8674(81)90358-5  1
1981 Stock JB, Koshland DE. Changing reactivity of receptor carboxyl groups during bacterial sensing. The Journal of Biological Chemistry. 256: 10826-33. PMID 7026562  1
1981 DeFranco AL, Koshland DE. Molecular cloning of chemotaxis genes and overproduction of gene products in the bacterial sensing system Journal of Bacteriology. 147: 390-400. PMID 7021528 DOI: 10.1128/Jb.147.2.390-400.1981  1
1981 Snyder MA, Koshland DE. Identification of the esterase peptide and its interaction with the cheZ peptide in bacterial sensing. Biochimie. 63: 113-7. PMID 7013822 DOI: 10.1016/S0300-9084(81)80174-5  1
1981 Goldbeter A, Koshland DE. An amplified sensitivity arising from covalent modification in biological systems Proceedings of the National Academy of Sciences of the United States of America. 78: 6840-6844. PMID 6947258 DOI: 10.1073/Pnas.78.11.6840  1
1981 Snyder MA, Stock JB, Koshland DE. Role of membrane potential and calcium in chemotactic sensing by bacteria. Journal of Molecular Biology. 149: 241-57. PMID 6796698 DOI: 10.1016/0022-2836(81)90300-4  1
1981 Stock JB, Koshland DE. A cyclic mechanism for excitation and adaptation. Current Topics in Cellular Regulation. 18: 505-17. PMID 6791879 DOI: 10.1016/B978-0-12-152818-8.50036-0  1
1981 Koshland DE. Biochemistry of sensing and adaptation in a simple bacterial system. Annual Review of Biochemistry. 50: 765-82. PMID 6791579 DOI: 10.1146/annurev.bi.50.070181.004001  0.01
1981 Wang JYJ, Clegg DO, Koshland DE. Molecular cloning and amplification of the adenylate cyclase gene Proceedings of the National Academy of Sciences of the United States of America. 78: 4684-4688. PMID 6272270 DOI: 10.1073/Pnas.78.8.4684  1
1980 Clarke S, Sparrow K, Panasenko S, Koshland DE. In vitro methylation of bacterial chemotaxis proteins: characterization of protein methyltransferase activity in crude extracts of Salmonella typhimurium. Journal of Supramolecular Structure. 13: 315-28. PMID 7009989 DOI: 10.1002/jss.400130305  1
1980 Wang EA, Koshland DE. Receptor structure in the bacterial sensing system. Proceedings of the National Academy of Sciences of the United States of America. 77: 7157-61. PMID 6784119 DOI: 10.1073/Pnas.77.12.7157  1
1980 Koshland DE, Anderson MJ. Effect of catabolite repression on chemotaxis in Salmonella typhimurium Molecular Biology, Biochemistry, and Biophysics. 32: 136-143. PMID 6777655  1
1980 Koshland DE. Bacterial chemotaxis in relation to neurobiology. Annual Review of Neuroscience. 3: 43-75. PMID 6774654 DOI: 10.1146/annurev.ne.03.030180.000355  0.01
1980 Miller JB, Koshland DE. Protonmotive force and bacterial sensing. Journal of Bacteriology. 141: 26-32. PMID 6766440 DOI: 10.1128/Jb.141.1.26-32.1980  1
1980 DeFranco AL, Koshland DE. Multiple methylation in processing of sensory signals during bacterial chemotaxis Proceedings of the National Academy of Sciences of the United States of America. 77: 2429-2433. PMID 6446711 DOI: 10.1073/Pnas.77.5.2429  1
1979 Clarke S, Koshland DE. The effect of protein modification reagents on the chemotactic response in Salmonella typhimurium. Canadian Journal of Biochemistry. 57: 1331-6. PMID 396013 DOI: 10.1139/O79-177  1
1979 Zukin RS, Hartig PR, Koshland DE. Effect of an induced conformational change on the physical properties of two chemotactic receptor molecules. Biochemistry. 18: 5599-605. PMID 391272 DOI: 10.1021/Bi00592A012  1
1979 Taylor BL, Miller JB, Warrick HM, Koshland DE. Electron acceptor taxis and blue light effect on bacterial chemotaxis. Journal of Bacteriology. 140: 567-73. PMID 387740 DOI: 10.1128/Jb.140.2.567-573.1979  1
1979 Koshland DE. A model regulatory system: bacterial chemotaxis. Physiological Reviews. 59: 811-62. PMID 386396 DOI: 10.1152/physrev.1979.59.4.811  0.01
1979 Paoni NF, Koshland DE. Permeabilization of cells for studies on the biochemistry of bacterial chemotaxis. Proceedings of the National Academy of Sciences of the United States of America. 76: 3693-7. PMID 386344 DOI: 10.1073/Pnas.76.8.3693  0.01
1979 Clarke S, Koshland DE. Membrane receptors for aspartate and serine in bacterial chemotaxis. The Journal of Biological Chemistry. 254: 9695-702. PMID 385590  1
1979 Spudich JL, Koshland DE. Specific inactivator of flagellar reversal in Salmonella typhimurium Journal of Bacteriology. 139: 442-447. PMID 378971 DOI: 10.1128/Jb.139.2.442-447.1979  1
1979 DeFranco AL, Parkinson JS, Koshland DE. Functional homology of chemotaxis genes in Escherichia coli and Salmonella typhimurium Journal of Bacteriology. 139: 107-114. PMID 378950 DOI: 10.1128/Jb.139.1.107-114.1979  1
1979 Fahnestock M, Koshland DE. Control of the receptor for galactose taxis in Salmonella typhimurium. Journal of Bacteriology. 137: 758-63. PMID 370099 DOI: 10.1128/Jb.137.2.758-763.1979  0.12
1979 Ingolia TD, Koshland DE. Response to a metal ion-citrate complex in bacterial sensing. Journal of Bacteriology. 140: 798-804. PMID 160411 DOI: 10.1128/Jb.140.3.798-804.1979  0.04
1978 Koshland DE. Heredity, environment, and chance in the responses of an individual cell. Birth Defects Original Article Series. 14: 401-15. PMID 638243  0.01
1978 Miller JB, Koshland DE. Effects of cyanine dye membrane probes on cellular properties. Nature. 272: 83-4. PMID 415251 DOI: 10.1038/272083A0  1
1978 Khan S, Macnab RM, DeFranco AL, Koshland DE. Inversion of a behavioral response in bacterial chemotaxis: explanation at the molecular level Proceedings of the National Academy of Sciences of the United States of America. 75: 4150-4154. PMID 360210 DOI: 10.1073/Pnas.75.9.4150  1
1978 Stock JB, Koshland DE. A protein methylesterase involved in bacterial sensing. Proceedings of the National Academy of Sciences of the United States of America. 75: 3659-63. PMID 358191 DOI: 10.1073/Pnas.75.8.3659  1
1978 Rubik BA, Koshland DE. Potentiation, desensitization, and inversion of response in bacterial sensing of chemical stimuli Proceedings of the National Academy of Sciences of the United States of America. 75: 2820-2824. PMID 351616 DOI: 10.1073/Pnas.75.6.2820  1
1978 Byers LD, Koshland DE. On the mechanism of action of methyl chymotrypsin Bioorganic Chemistry. 7: 15-33. DOI: 10.1016/0045-2068(78)90014-7  1
1977 Koshland DE. A response regulator model in a simple sensory system. Science (New York, N.Y.). 196: 1055-63. PMID 870969  0.01
1977 Miller JB, Koshland DE. Sensory electrophysiology of bacteria: relationship of the membrane potential to motility and chemotaxis in Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America. 74: 4752-6. PMID 412194 DOI: 10.1073/Pnas.74.11.4752  1
1977 Zukin RS, Hartig PR, Koshland DE. Use of a distant reporter group as evidence for a conformational change in a sensory receptor. Proceedings of the National Academy of Sciences of the United States of America. 74: 1932-6. PMID 325561 DOI: 10.1073/Pnas.74.5.1932  1
1977 Miller JB, Koshland DE. Membrane fluidity and chemotaxis: effects of temperature and membrane lipid composition on the swimming behavior of Salmonella typhimurium and Escherichia coli. Journal of Molecular Biology. 111: 183-201. PMID 323503 DOI: 10.1016/S0022-2836(77)80122-8  1
1977 Van Der Werf P, Koshland DE. Identification of a gamma-glutamyl methyl ester in bacterial membrane protein involved in chemotaxis. The Journal of Biological Chemistry. 252: 2793-5. PMID 323255  0.01
1977 Warrick HM, Taylor BL, Koshland DE. Chemotactic mechanism of Salmonella typhimurium: preliminary mapping and characterization of mutants Journal of Bacteriology. 130: 223-231. PMID 323229 DOI: 10.1128/Jb.130.1.223-231.1977  1
1977 Springer WR, Koshland DE. Identification of a protein methyltransferase as the cheR gene product in the bacterial sensing system Proceedings of the National Academy of Sciences of the United States of America. 74: 533-537. PMID 322131  1
1977 Zukin RS, Strange PG, Heavey R, Koshland DE. Properties of the galactose binding protein of Salmonella typhimurium and Escherichia coli. Biochemistry. 16: 381-6. PMID 319823  1
1976 Taylor BL, Koshland DE. Perturbation of the chemotactic tumbling of bacteria Journal of Supramolecular and Cellular Biochemistry. 4: 343-353. PMID 1263512 DOI: 10.1002/Jss.400040305  1
1976 Spudich JL, Koshland DE. Non-genetic individuality: Chance in the single cell Nature. 262: 467-471. PMID 958399 DOI: 10.1038/262467A0  1
1976 Strange PG, Koshland DE. Receptor interactions in a signalling system: competition between ribose receptor and galactose receptor in the chemotaxis response. Proceedings of the National Academy of Sciences of the United States of America. 73: 762-6. PMID 768985  1
1976 Zukin RS, Koshland DE. Mg2+, Ca2+-dependent adenosine triphosphatase as receptor for divalent cations in bacterial sensing. Science (New York, N.Y.). 193: 405-8. PMID 132702 DOI: 10.1126/Science.132702  1
1975 Aswad D, Koshland DE. Isolation, characterization and complementation of Salmonella typhimurium chemotaxis mutants Journal of Molecular Biology. 97: 225-235. PMID 1100857 DOI: 10.1016/S0022-2836(75)80036-2  1
1975 Aswad DW, Koshland DE. Evidence for an S-adenosylmethionine requirement in the chemotactic behavior of Salmonella typhimurium. Journal of Molecular Biology. 97: 207-23. PMID 1100856 DOI: 10.1016/S0022-2836(75)80035-0  1
1975 Taylor BL, Koshland DE. Intrinsic and extrinsic light responses of Salmonella typhimurium and Escherichia coli Journal of Bacteriology. 123: 557-569. PMID 1097417 DOI: 10.1128/Jb.123.2.557-569.1975  1
1975 Spudich JL, Koshland DE. Quantitation of the sensory response in bacterial chemotaxis Proceedings of the National Academy of Sciences of the United States of America. 72: 710-713. PMID 1091931 DOI: 10.1073/Pnas.72.2.710  1
1975 Aksamit RR, Howlett BJ, Koshland DE. Soluble and membrane-bound aspartate-binding activities in Salmonella typhimurium. Journal of Bacteriology. 123: 1000-5. PMID 239919 DOI: 10.1128/Jb.123.3.1000-1005.1975  1
1975 Cornish-Bowden A, Koshland DE. Diagnostic uses of the Hill (logit and Nernst) plots Journal of Molecular Biology. 95: 201-212. PMID 171413 DOI: 10.1016/0022-2836(75)90390-3  1
1975 Byers LD, Koshland DE. The specificity of induced conformational changes. The case of yeast glyceraldehyde-3-phosphate dehydrogenase. Biochemistry. 14: 3661-9. PMID 169882  1
1975 Mockrin SC, Byers LD, Koshland DE. Subunit interactions in yeast glyceraldehyde-3-phosphate dehydrogenase. Biochemistry. 14: 5428-37. PMID 55 DOI: 10.1021/Bi00696A008  1
1974 Macnab R, Koshland DE. Bacterial motility and chemotaxis: light-induced tumbling response and visualization of individual flagella. Journal of Molecular Biology. 84: 399-406. PMID 4618854 DOI: 10.1016/0022-2836(74)90448-3  1
1974 Aksamit RR, Koshland DE. Identification of the ribose binding protein as the receptor for ribose chemotaxis in Salmonella typhimurium. Biochemistry. 13: 4473-8. PMID 4609457 DOI: 10.1021/Bi00719A001  1
1974 Taylor BL, Koshland DE. Reversal of flagellar rotation in monotrichous and peritrichous bacteria: generation of changes in direction. Journal of Bacteriology. 119: 640-2. PMID 4605064 DOI: 10.1128/Jb.119.2.640-642.1974  1
1974 Aswad D, Koshland DE. Role of methionine in bacterial chemotaxis Journal of Bacteriology. 118: 640-645. PMID 4597455 DOI: 10.1128/Jb.118.2.640-645.1974  1
1974 Lovely P, Dahlquist FW, Macnab R, Koshland DE. An instrument for recording the motions of microorganisms in chemical gradients Review of Scientific Instruments. 45: 683-686. PMID 4596820 DOI: 10.1063/1.1686713  1
1974 Bell RM, Parsons SM, Dubravac SA, Redfield AG, Koshland DE. Characterization of slowly interconvertible states of phosphoribosyladenosine triphosphate synthetase dependent on temperature, substrates, and histidine. The Journal of Biological Chemistry. 249: 4110-8. PMID 4368489  1
1974 Taylor BL, Koshland DE. Reversal of flagellar rotation in monotrichous and peritrichous bacteria: generation of changes in direction Journal of Bacteriology. 119: 640-642.  1
1973 Macnab R, Koshland DE. Persistence as a concept in the motility of chemotactic bacteria. Journal of Mechanochemistry & Cell Motility. 2: 141-8. PMID 4595421  1
1973 Tsang N, Macnab R, Koshland DE. Common mechanism for repellents and attractants in bacterial chemotaxis. Science (New York, N.Y.). 181: 60-3. PMID 4576832 DOI: 10.1126/science.181.4094.60  1
1972 Loudon GM, Koshland DE. Diagnostic relationships in the relaxation spectrometry of allosteric enzymes. Biochemistry. 11: 229-41. PMID 5009442  1
1972 Macnab RM, Koshland DE. The gradient-sensing mechanism in bacterial chemotaxis Proceedings of the National Academy of Sciences of the United States of America. 69: 2509-2512. PMID 4560688 DOI: 10.1073/Pnas.69.9.2509  1
1972 Dahlquist FW, Lovely P, Koshland DE. Quantitative analysis of bacterial migration in chemotaxis Nature: New Biology. 236: 120-123. PMID 4554379  1
1972 Koshland DE, Carraway KW, Dafforn GA, Gass JD, Storm DR. The importance of orientation factors in enzymatic reactions. Cold Spring Harbor Symposia On Quantitative Biology. 36: 13-20. PMID 4508130 DOI: 10.1101/Sqb.1972.036.01.005  1
1972 Storm DR, Koshland DE. Indication of the magnitude of orientation factors in esterification Journal of the American Chemical Society. 94: 5805-5814. DOI: 10.1021/JA00771A045  0.36
1972 STORM DR, KOSHLAND DEJ. ChemInform Abstract: EINFLUSS KLEINER AENDERUNGEN DER ORIENTIERUNG AUF DIE RK.-GESCHWINDIGKEIT Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/CHIN.197244159  0.32
1971 Bell RM, Koshland DE. Covalent enzyme-substrate intermediates. Science (New York, N.Y.). 172: 1253-6. PMID 5576163 DOI: 10.1126/Science.172.3989.1253  1
1971 Cornish-Bowden AJ, Koshland DE. The quaternary structure of proteins composed of identical subunits Journal of Biological Chemistry. 246: 3092-3102. PMID 5574388  1
1971 Haber JE, Koshland DE. The effect of 2,3-diphosphoglyceric acid on the changes in - interactions in hemoglobin during oxygenation. The Journal of Biological Chemistry. 246: 7790-3. PMID 5135320  1
1971 Storm DR, Tjian R, Koshland DE. Rate accelerations by alteration in the orientation of reacting atoms. Comparison of lactonizations in bicyclo[2,2,2] and bicyclo[2,2,1] ring structures Journal of the Chemical Society D: Chemical Communications. 854-855. DOI: 10.1039/C29710000854  1
1970 Storm DR, Koshland DE. A source for the special catalytic power of enzymes: orbital steering. Proceedings of the National Academy of Sciences of the United States of America. 66: 445-52. PMID 16591843 DOI: 10.1073/Pnas.66.2.445  1
1970 Cornish-Bowden A, Koshland DE. The influence of binding domains on the nature of subunit interactions in oligomeric proteins. Application to unusual kinetic and binding patterns Journal of Biological Chemistry. 245: 6241-6250. PMID 5484808  1
1970 Loudon GM, Koshland DE. The chemistry of a reporter group: 2-hydroxy-5-nitrobenzyl bromide. The Journal of Biological Chemistry. 245: 2247-54. PMID 5442270  1
1970 Cook RA, Koshland DE. Positive and negative cooperativity in yeast glyceraldehyde 3-phosphate dehydrogenase. Biochemistry. 9: 3337-42. PMID 4330855 DOI: 10.1021/BI00819A007  1
1970 Cornish-Bowden A, Koshland DE. A general method for the quantitative determination of saturation curves for multisubunit proteins Biochemistry. 9: 3325-3336. PMID 4330854 DOI: 10.1021/Bi00819A006  1
1970 Cornish-Bowden AJ, Cook RA, Koshland DE. A curve-fitting procedure for the study of the binding of small molecules to multi-subunit proteins Il Farmaco; Edizione Scientifica. 25: 786-798. PMID 4320826  1
1970 Bell RM, Koshland DE. A phosphoribosyl-enzyme covalent intermediate in the first enzyme of histidine biosynthesis. Biochemical and Biophysical Research Communications. 38: 539-45. PMID 4315351 DOI: 10.1016/0006-291X(70)90614-5  1
1970 Haber JE, Koshland DE. An evaluation of the relatedness of proteins based on comparison of amino acid sequences. Journal of Molecular Biology. 50: 617-39. PMID 4097749 DOI: 10.1016/0022-2836(70)90089-6  1
1969 Loudon GM, Portsmouth D, Lukton A, Koshland DE. The chemistry of the modification of tryptophan with 2-hydroxy-5-nitrobenzyl bromide. Journal of the American Chemical Society. 91: 2792-4. PMID 5784953 DOI: 10.1021/Ja01038A068  1
1969 Haber JE, Koshland DE. Evidence for beta--beta interactions during the binding of oxygen to hemoglobin. Biochimica Et Biophysica Acta. 194: 339-41. PMID 5353133 DOI: 10.1016/0005-2795(69)90215-3  1
1969 Cook RA, Koshland DE. Specificity in the assembly of multisubunit proteins. Proceedings of the National Academy of Sciences of the United States of America. 64: 247-54. PMID 4904641 DOI: 10.1073/PNAS.64.1.247  1
1968 Koshland DE, Neet KE. The catalytic and regulatory properties of enzymes Annual Review of Biochemistry. 37: 359-410. PMID 4877056 DOI: 10.1146/ANNUREV.BI.37.070168.002043  1
1967 Hille MB, Koshland DE. The environment of a reporter group at the active site of chymotrypsin. Journal of the American Chemical Society. 89: 5945-51. PMID 6073146 DOI: 10.1021/Ja00999A036  1
1967 Haber JE, Koshland DE. Relation of protein subunit interactions to the molecular species observed during cooperative binding of ligands. Proceedings of the National Academy of Sciences of the United States of America. 58: 2087-93. PMID 5237502 DOI: 10.1073/Pnas.58.5.2087  1
1966 Neet KE, Koshland DE. The conversion of serine at the active site of subtilisin to cysteine: a "chemical mutation" Proceedings of the National Academy of Sciences of the United States of America. 56: 1606-1611. PMID 5230319 DOI: 10.1073/PNAS.56.5.1606  1
1963 YOUNT RG, KOSHLAND DE. Properties of the O18 exchange reaction catalyzed by heavy meromyosin. The Journal of Biological Chemistry. 238: 1708-13. PMID 14002855  1
1962 Levy HM, Sharon N, Ryan EM, Koshland DE. Effect of temperature on the rate of hydrolysis of adenosine triphosphate and inosine triphosphate by myosin with and without modifiers. Evidence for a change in protein conformation Bba - Biochimica Et Biophysica Acta. 56: 118-126. PMID 14464767 DOI: 10.1016/0006-3002(62)90532-2  1
1962 KOSHLAND DE, STRUMEYER DH, RAY WJ. Amino acids involved in the action of chymotrypsin. Brookhaven Symposia in Biology. 15: 101-33. PMID 14034953  1
1960 RAY WJ, KOSHLAND DE. Comparative structural studies of phosphoglucomutase and chymotrypsin. Brookhaven Symposia in Biology. 13: 135-50. PMID 13739953  1
1959 Koshland ME, Englberger F, Koshland DE. A GENERAL METHOD FOR THE LABELING OF THE ACTIVE SITE OF ANTIBODIES AND ENZYMES. Proceedings of the National Academy of Sciences of the United States of America. 45: 1470-5. PMID 16590528 DOI: 10.1073/Pnas.45.10.1470  0.01
1959 Levy HM, Sharon N, Koshland DE. PURIFIED MUSCLE PROTEINS AND THE WALKING RATE OF ANTS. Proceedings of the National Academy of Sciences of the United States of America. 45: 785-91. PMID 16590444 DOI: 10.1073/Pnas.45.6.785  0.01
1959 Levy HM, Sharon N, Koshland DE. A mechanism for the effects of dinitrophenol and temperature on the hydrolytic activity of myosin Bba - Biochimica Et Biophysica Acta. 33: 288-289. PMID 13651228 DOI: 10.1016/0006-3002(59)90542-6  1
1958 Koshland DE. Application of a Theory of Enzyme Specificity to Protein Synthesis. Proceedings of the National Academy of Sciences of the United States of America. 44: 98-104. PMID 16590179  0.01
1958 PARK JH, KOSHLAND DE. The hydrolytic activity of glyceraldehyde-3-phosphate dehydrogenase. The Journal of Biological Chemistry. 233: 986-90. PMID 13587528  0.88
1950 Koshland DE, Westheimer FH. Mechanism of alcoholic fermentation. The fermentation of glucose-1-C14 Journal of the American Chemical Society. 72: 3383-3388.  1
1949 KOSHLAND D, WESTHEIMER FH. Fermentation of glucose-1-C14. Journal of the American Chemical Society. 71: 1139. PMID 18113554 DOI: 10.1021/Ja01171A534  1
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