William R. Shadrick, Ph.D. - Publications

Affiliations: 
2010 Biochemistry University of Maryland, College Park, College Park, MD 

11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Zhao Y, Shadrick WR, Wallace MJ, Wu Y, Griffith EC, Qi J, Yun MK, White SW, Lee RE. Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents. Bioorganic & Medicinal Chemistry Letters. PMID 27423480 DOI: 10.1016/j.bmcl.2016.07.006  1
2016 Song MS, Kumar G, Shadrick WR, Zhou W, Jeevan T, Li Z, Slavish PJ, Fabrizio TP, Yoon SW, Webb TR, Webby RJ, White SW. Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976575 DOI: 10.1073/pnas.1519772113  1
2016 Ling T, Gautam LN, Griffith E, Das S, Lang W, Shadrick WR, Shelat A, Lee R, Rivas F. Synthesis and evaluation of colletoic acid core derivatives. European Journal of Medicinal Chemistry. 110: 126-132. PMID 26820555 DOI: 10.1016/j.ejmech.2016.01.027  1
2014 McCallum MM, Pawlak AJ, Shadrick WR, Simeonov A, Jadhav A, Yasgar A, Maloney DJ, Arnold LA. A fluorescence-based high throughput assay for the determination of small molecule-human serum albumin protein binding. Analytical and Bioanalytical Chemistry. 406: 1867-75. PMID 24390461 DOI: 10.1007/s00216-013-7560-3  1
2013 Shadrick WR, Mukherjee S, Hanson AM, Sweeney NL, Frick DN. Aurintricarboxylic acid modulates the affinity of hepatitis C virus NS3 helicase for both nucleic acid and ATP. Biochemistry. 52: 6151-9. PMID 23947785 DOI: 10.1021/bi4006495  1
2013 Sweeney NL, Shadrick WR, Mukherjee S, Li K, Frankowski KJ, Schoenen FJ, Frick DN. Primuline derivatives that mimic RNA to stimulate hepatitis C virus NS3 helicase-catalyzed ATP hydrolysis. The Journal of Biological Chemistry. 288: 19949-57. PMID 23703611 DOI: 10.1074/jbc.M113.463166  1
2013 Shadrick WR, Ndjomou J, Kolli R, Mukherjee S, Hanson AM, Frick DN. Discovering new medicines targeting helicases: challenges and recent progress. Journal of Biomolecular Screening. 18: 761-81. PMID 23536547 DOI: 10.1177/1087057113482586  1
2012 Ndjomou J, Kolli R, Mukherjee S, Shadrick WR, Hanson AM, Sweeney NL, Bartczak D, Li K, Frankowski KJ, Schoenen FJ, Frick DN. Fluorescent primuline derivatives inhibit hepatitis C virus NS3-catalyzed RNA unwinding, peptide hydrolysis and viral replicase formation. Antiviral Research. 96: 245-55. PMID 22940425 DOI: 10.1016/j.antiviral.2012.08.006  1
2012 Mukherjee S, Hanson AM, Shadrick WR, Ndjomou J, Sweeney NL, Hernandez JJ, Bartczak D, Li K, Frankowski KJ, Heck JA, Arnold LA, Schoenen FJ, Frick DN. Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays. Nucleic Acids Research. 40: 8607-21. PMID 22740655 DOI: 10.1093/nar/gks623  1
2012 Hanson AM, Hernandez JJ, Shadrick WR, Frick DN. Identification and analysis of inhibitors targeting the hepatitis C virus NS3 helicase. Methods in Enzymology. 511: 463-83. PMID 22713333 DOI: 10.1016/B978-0-12-396546-2.00021-8  1
2010 Shadrick WR, Julin DA. Kinetics of DNA unwinding by the RecD2 helicase from Deinococcus radiodurans. The Journal of Biological Chemistry. 285: 17292-300. PMID 20360003 DOI: 10.1074/jbc.M110.111427  1
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