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William R. Shadrick, Ph.D. - Publications

Affiliations: 
2010 Biochemistry University of Maryland, College Park, College Park, MD 
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2/23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Miao Y, Tenor JL, Toffaletti DL, Washington EJ, Liu J, Shadrick WR, Schumacher MA, Lee RE, Perfect JR, Brennan RG. Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27307435 DOI: 10.1073/Pnas.1601774113  0.306
2012 Hanson AM, Hernandez JJ, Shadrick WR, Frick DN. Identification and analysis of inhibitors targeting the hepatitis C virus NS3 helicase. Methods in Enzymology. 511: 463-83. PMID 22713333 DOI: 10.1016/B978-0-12-396546-2.00021-8  0.311
Low-probability matches (unlikely to be authored by this person)
2013 Shadrick WR, Mukherjee S, Hanson AM, Sweeney NL, Frick DN. Aurintricarboxylic acid modulates the affinity of hepatitis C virus NS3 helicase for both nucleic acid and ATP. Biochemistry. 52: 6151-9. PMID 23947785 DOI: 10.1021/Bi4006495  0.285
2013 Shadrick WR, Ndjomou J, Kolli R, Mukherjee S, Hanson AM, Frick DN. Discovering new medicines targeting helicases: challenges and recent progress. Journal of Biomolecular Screening. 18: 761-81. PMID 23536547 DOI: 10.1177/1087057113482586  0.248
2016 Zhao Y, Shadrick WR, Wallace MJ, Wu Y, Griffith EC, Qi J, Yun MK, White SW, Lee RE. Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents. Bioorganic & Medicinal Chemistry Letters. PMID 27423480 DOI: 10.1016/j.bmcl.2016.07.006  0.234
2012 Mukherjee S, Hanson AM, Shadrick WR, Ndjomou J, Sweeney NL, Hernandez JJ, Bartczak D, Li K, Frankowski KJ, Heck JA, Arnold LA, Schoenen FJ, Frick DN. Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays. Nucleic Acids Research. 40: 8607-21. PMID 22740655 DOI: 10.1093/Nar/Gks623  0.231
2014 McCallum MM, Pawlak AJ, Shadrick WR, Simeonov A, Jadhav A, Yasgar A, Maloney DJ, Arnold LA. A fluorescence-based high throughput assay for the determination of small molecule-human serum albumin protein binding. Analytical and Bioanalytical Chemistry. 406: 1867-75. PMID 24390461 DOI: 10.1007/S00216-013-7560-3  0.197
2012 Ndjomou J, Kolli R, Mukherjee S, Shadrick WR, Hanson AM, Sweeney NL, Bartczak D, Li K, Frankowski KJ, Schoenen FJ, Frick DN. Fluorescent primuline derivatives inhibit hepatitis C virus NS3-catalyzed RNA unwinding, peptide hydrolysis and viral replicase formation. Antiviral Research. 96: 245-55. PMID 22940425 DOI: 10.1016/J.Antiviral.2012.08.006  0.185
2022 Cibelli N, Arias G, Figur M, Khayat SS, Leach K, Loukinov I, Shadrick W, Chuenchor W, Tsybovsky Y, Gulla K, Gowetski DB. Advances in purification of SARS-CoV-2 spike ectodomain protein using high-throughput screening and non-affinity methods. Scientific Reports. 12: 4458. PMID 35292666 DOI: 10.1038/s41598-022-07485-w  0.176
2016 Ling T, Gautam LN, Griffith E, Das S, Lang W, Shadrick WR, Shelat A, Lee R, Rivas F. Synthesis and evaluation of colletoic acid core derivatives. European Journal of Medicinal Chemistry. 110: 126-132. PMID 26820555 DOI: 10.1016/J.Ejmech.2016.01.027  0.151
2013 Mannan MA, Shadrick WR, Biener G, Shin BS, Anshu A, Raicu V, Frick DN, Dey M. An ire1-phk1 chimera reveals a dispensable role of autokinase activity in endoplasmic reticulum stress response. Journal of Molecular Biology. 425: 2083-99. PMID 23541589 DOI: 10.1016/J.Jmb.2013.02.036  0.133
2017 Shadrick WR, Slavish PJ, Chai SC, Waddell B, Connelly M, Low JA, Tallant C, Young BM, Bharatham N, Knapp S, Boyd VA, Morfouace M, Roussel MF, Chen T, Lee RE, et al. Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors. Bioorganic & Medicinal Chemistry. PMID 29170024 DOI: 10.1016/J.Bmc.2017.10.042  0.132
2013 Sweeney NL, Shadrick WR, Mukherjee S, Li K, Frankowski KJ, Schoenen FJ, Frick DN. Primuline derivatives that mimic RNA to stimulate hepatitis C virus NS3 helicase-catalyzed ATP hydrolysis. The Journal of Biological Chemistry. 288: 19949-57. PMID 23703611 DOI: 10.1074/Jbc.M113.463166  0.129
2019 Griffith E, Zhao Y, Singh A, Conlon B, Tangallapally R, Shadrick W, Liu J, Wallace M, Yang L, Elmore J, Li Y, Zheng Z, Miller DJ, Cheramie M, Lee RB, et al. Ureadepsipeptides as ClpP Activators. Acs Infectious Diseases. PMID 31588734 DOI: 10.1021/acsinfecdis.9b00245  0.123
2009 Ward TR, Turunen BJ, Haack T, Neuenswander B, Shadrick W, Georg GI. Synthesis of a quinolone library from ynones. Tetrahedron Letters. 50: 6494-9497. PMID 20161410 DOI: 10.1016/J.Tetlet.2009.09.024  0.115
2015 Shi Y, Joyner AS, Shadrick W, Palacios G, Lagisetti C, Potter PM, Sambucetti LC, Stamm S, Webb TR. Pharmacodynamic assays to facilitate preclinical and clinical development of pre-mRNA splicing modulatory drug candidates. Pharmacology Research & Perspectives. 3: e00158. PMID 26171237 DOI: 10.1002/Prp2.158  0.097
2022 Gollapudi D, Shadrick W, Yang Y, Gowetski DB, Gall J, Paula Lei Q. Quantification of prefusion conformation for HIV vaccine using size-exclusion chromatography. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 123296. PMID 35598458 DOI: 10.1016/j.jchromb.2022.123296  0.088
2020 Slavish PJ, Chi L, Yun MK, Tsurkan L, Martinez NE, Jonchere B, Chai SC, Connelly M, Waddell MB, Das S, Neale G, Li Z, Shadrick WR, Olsen RR, Freeman KW, et al. Bromodomain-selective BET inhibitors are potent antitumor agents against MYC-driven pediatric cancer. Cancer Research. PMID 32651255 DOI: 10.1158/0008-5472.Can-19-3934  0.085
2016 Song MS, Kumar G, Shadrick WR, Zhou W, Jeevan T, Li Z, Slavish PJ, Fabrizio TP, Yoon SW, Webb TR, Webby RJ, White SW. Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976575 DOI: 10.1073/Pnas.1519772113  0.08
2010 Ward TR, Turunen BJ, Haack T, Neuenswander B, Shadrick W, Georg GI. ChemInform Abstract: Synthesis of a Quinolone Library from Ynones. Cheminform. 41. DOI: 10.1002/chin.201010152  0.078
2010 Shadrick WR, Julin DA. Kinetics of DNA unwinding by the RecD2 helicase from Deinococcus radiodurans. The Journal of Biological Chemistry. 285: 17292-300. PMID 20360003 DOI: 10.1074/Jbc.M110.111427  0.074
2022 Cai CX, Doria-Rose NA, Schneck NA, Ivleva VB, Tippett B, Shadrick WR, O'Connell S, Cooper JW, Schneiderman Z, Zhang B, Gowetski DB, Blackstock D, Demirji J, Lin BC, Gorman J, et al. Tyrosine O-sulfation proteoforms affect HIV-1 monoclonal antibody potency. Scientific Reports. 12: 8433. PMID 35589938 DOI: 10.1038/s41598-022-12423-x  0.072
2024 Yang RS, Traver M, Barefoot N, Stephens T, Alabanza C, Manzella-Lapeira J, Zou G, Wolff J, Li Y, Resto M, Shadrick W, Yang Y, Ivleva VB, Tsybovsky Y, Carlton K, et al. Mosaic quadrivalent influenza vaccine single nanoparticle characterization. Scientific Reports. 14: 4534. PMID 38402303 DOI: 10.1038/s41598-024-54876-2  0.047
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