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Richard S. Blumberg - Publications

Affiliations: 
2003 Immunology Harvard Medical School, Boston, MA, United States 
Website:
http://www.hms.harvard.edu/dms/immunology/fac/Blumberg.php
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Year Citation  Score
2022 Matsuzawa-Ishimoto Y, Yao X, Koide A, Ueberheide BM, Axelrad JE, Reis BS, Parsa R, Neil JA, Devlin JC, Rudensky E, Dewan MZ, Cammer M, Blumberg RS, Ding Y, Ruggles KV, et al. The γδ IEL effector API5 masks genetic susceptibility to Paneth cell death. Nature. PMID 36198790 DOI: 10.1038/s41586-022-05259-y  0.331
2022 Saveljeva S, Sewell GW, Ramshorn K, Cader MZ, West JA, Clare S, Haag LM, de Almeida Rodrigues RP, Unger LW, Iglesias-Romero AB, Holland LM, Bourges C, Md-Ibrahim MN, Jones JO, Blumberg RS, et al. A purine metabolic checkpoint that prevents autoimmunity and autoinflammation. Cell Metabolism. 34: 106-124.e10. PMID 34986329 DOI: 10.1016/j.cmet.2021.12.009  0.311
2021 Quintero M, Liu S, Xia Y, Huang Y, Zou Y, Li G, Hu L, Singh N, Blumberg R, Cai Y, Xu H, Li H. Cdk5rap3 is essential for intestinal Paneth cell development and maintenance. Cell Death & Disease. 12: 131. PMID 33504792 DOI: 10.1038/s41419-021-03401-8  0.329
2020 Tsugawa N, Yamada D, Watabe T, Onizawa M, Wang S, Nemoto Y, Oshima S, Tsubata T, Adachi T, Kawano Y, Watanabe M, Blumberg RS, Okamoto R, Nagaishi T. CEACAM1 specifically suppresses B cell receptor signaling-mediated activation. Biochemical and Biophysical Research Communications. 535: 99-105. PMID 33352461 DOI: 10.1016/j.bbrc.2020.11.126  0.306
2020 Stengel ST, Fazio A, Lipinski S, Jahn MT, Aden K, Ito G, Wottawa F, Kuiper JWP, Coleman OI, Tran F, Bordoni D, Bernardes JP, Jentzsch M, Luzius A, Bierwirth S, ... ... Blumberg R, et al. Activating Transcription Factor 6 Mediates Inflammatory Signals in Intestinal Epithelial Cells Upon Endoplasmic Reticulum Stress. Gastroenterology. PMID 32673694 DOI: 10.1053/J.Gastro.2020.06.088  0.338
2020 Hubbard JJ, Pyzik M, Rath T, Kozicky LK, Sand KMK, Gandhi AK, Grevys A, Foss S, Menzies SC, Glickman JN, Fiebiger E, Roopenian DC, Sandlie I, Andersen JT, Sly LM, ... ... Blumberg RS, et al. FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity. The Journal of Experimental Medicine. 217. PMID 32658257 DOI: 10.1084/Jem.20200359  0.351
2020 Cines DB, Zaitsev S, Rauova L, Rux AH, Stepanova V, Krishnaswamy S, Sarkar A, Kowalska MA, Zhao G, Mast AE, Blumberg LJ, McCrae KR, Poncz M, Hubbard JJ, Pyzik M, ... Blumberg RS, et al. FcRn augments induction of tissue factor activity by IgG-containing immune complexes. Blood. PMID 32187355 DOI: 10.1182/Blood.2019001133  0.337
2019 Blumberg LJ, Humphries JE, Jones SD, Pearce LB, Holgate R, Hearn A, Cheung J, Mahmood A, Del Tito B, Graydon JS, Stolz LE, Bitonti A, Purohit S, de Graaf D, Kacena K, ... ... Blumberg RS, et al. Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses. Science Advances. 5: eaax9586. PMID 31897428 DOI: 10.1126/Sciadv.Aax9586  0.364
2019 Bedard M, Shrestha D, Priestman DA, Wang Y, Schneider F, Matute JD, Iyer SS, Gileadi U, Prota G, Kandasamy M, Veerapen N, Besra G, Fritzsche M, Zeissig S, Shevchenko A, ... ... Blumberg RS, et al. Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31690657 DOI: 10.1073/Pnas.1910097116  0.429
2019 Melum E, Jiang X, Baker KD, Macedo MF, Fritsch J, Dowds CM, Wang J, Pharo A, Kaser A, Tan C, Pereira CS, Kelly SL, Duan J, Karlsen TH, Exley MA, ... ... Blumberg RS, et al. Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin. Nature Immunology. PMID 31636468 DOI: 10.1038/S41590-019-0504-0  0.451
2019 Kim WM, Huang YH, Gandhi A, Blumberg RS. CEACAM1 structure and function in immunity and its therapeutic implications. Seminars in Immunology. 42: 101296. PMID 31604530 DOI: 10.1016/J.Smim.2019.101296  0.379
2019 Pyzik M, Sand KMK, Hubbard JJ, Andersen JT, Sandlie I, Blumberg RS. The Neonatal Fc Receptor (FcRn): A Misnomer? Frontiers in Immunology. 10: 1540. PMID 31354709 DOI: 10.3389/Fimmu.2019.01540  0.385
2019 Zeissig S, Blumberg RS. Analyzing Antigen Recognition by Natural Killer T Cells. Methods in Molecular Biology (Clifton, N.J.). 1988: 439-453. PMID 31147957 DOI: 10.1007/978-1-4939-9450-2_30  0.352
2019 Iyer SS, Huang YH, Blumberg RS. SLAM-ing the brakes on iNKT cell selection. Nature Immunology. PMID 30858622 DOI: 10.1038/S41590-019-0355-8  0.4
2019 Grootjans J, Krupka N, Hosomi S, Matute JD, Hanley T, Saveljeva S, Gensollen T, Heijmans J, Li H, Limenitakis JP, Ganal-Vonarburg SC, Suo S, Luoma AM, Shimodaira Y, Duan J, ... ... Blumberg RS, et al. Epithelial endoplasmic reticulum stress orchestrates a protective IgA response. Science (New York, N.Y.). 363: 993-998. PMID 30819965 DOI: 10.1126/Science.Aat7186  0.362
2019 Cai Y, Zhu G, Liu S, Pan Z, Quintero M, Poole CJ, Lu C, Zhu H, Islam B, Riggelen JV, Browning D, Liu K, Blumberg R, Singh N, Li H. Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation. Cell Discovery. 5: 7. PMID 30701081 DOI: 10.1038/S41421-018-0070-X  0.413
2019 Hubbard J, Pyzik M, Rath T, Andersen JT, Gandhi A, Foss S, Grevys A, Glickman JN, Fiebiger E, Roopenian D, Sandlie I, Baker K, Blumberg R. P150 THE HUMAN FC GAMMA RIIA H131 POLYMORPHISM IS A NEONATAL RECEPTOR (FCRN)-DEPENDENT HIGH RESPONDER VARIANT IN INFLAMMATORY BOWEL DISEASE Gastroenterology. 156: S98. DOI: 10.1053/J.Gastro.2019.01.229  0.304
2018 Gandhi AK, Kim WM, Sun ZJ, Huang YH, Bonsor DA, Sundberg EJ, Kondo Y, Wagner G, Kuchroo VK, Petsko G, Blumberg RS. High resolution X-ray and NMR structural study of human T-cell immunoglobulin and mucin domain containing protein-3. Scientific Reports. 8: 17512. PMID 30504845 DOI: 10.1038/S41598-018-35754-0  0.315
2018 Aires DJ, Yoshida M, Richardson SK, Bai M, Liu L, Moreno R, Lazar AJF, Wick JA, Rich BE, Murphy G, Blumberg RS, Fuhlbrigge RC, Kupper TS. T-cell trafficking plays an essential role in tumor immunity. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30353131 DOI: 10.1038/S41374-018-0124-6  0.34
2018 Li Y, Guan X, Liu W, Chen HL, Truscott J, Beyatli S, Metwali A, Weiner GJ, Zavazava N, Blumberg RS, Urban JF, Blazar BR, Elliott DE, Ince MN. Helminth-Induced Production of TGF-β and Suppression of Graft-versus-Host Disease Is Dependent on IL-4 Production by Host Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 30291167 DOI: 10.4049/Jimmunol.1700638  0.327
2018 Aden K, Tran F, Ito G, Sheibani-Tezerji R, Lipinski S, Kuiper JW, Tschurtschenthaler M, Saveljeva S, Bhattacharyya J, Häsler R, Bartsch K, Luzius A, Jentzsch M, Falk-Paulsen M, Stengel ST, ... ... Blumberg RS, et al. ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING. The Journal of Experimental Medicine. PMID 30254094 DOI: 10.1084/Jem.20171029  0.32
2018 Berntsen NL, Fosby B, Tan C, Reims HM, Ogaard J, Jiang X, Schrumpf E, Valestrand L, Karlsen TH, Line PD, Blumberg RS, Melum E. Natural killer T cells mediate inflammation in the bile ducts. Mucosal Immunology. PMID 30115993 DOI: 10.1038/S41385-018-0066-8  0.447
2018 Hosomi S, Grootjans J, Huang YH, Kaser A, Blumberg RS. New Insights Into the Regulation of Natural-Killer Group 2 Member D (NKG2D) and NKG2D-Ligands: Endoplasmic Reticulum Stress and CEA-Related Cell Adhesion Molecule 1. Frontiers in Immunology. 9: 1324. PMID 29973929 DOI: 10.3389/Fimmu.2018.01324  0.413
2018 Zhao M, Xiong X, Ren K, Xu B, Cheng M, Sahu C, Wu K, Nie Y, Huang Z, Blumberg RS, Han X, Ruan HB. Deficiency in intestinal epithelial O-GlcNAcylation predisposes to gut inflammation. Embo Molecular Medicine. PMID 29941542 DOI: 10.15252/Emmm.201708736  0.317
2018 Iyer SS, Gensollen T, Gandhi A, Oh SF, Neves JF, Collin F, Lavin R, Serra C, Glickman J, de Silva PSA, Sartor RB, Besra G, Hauser R, Maxwell A, Llebaria A, ... Blumberg RS, et al. Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses. Cell. 173: 1123-1134.e11. PMID 29775592 DOI: 10.1016/J.Cell.2018.04.037  0.408
2018 Lozano NA, Lozano A, Marini V, Saranz RJ, Blumberg RS, Baker K, Agresta MF, Ponzio MF. Expression of FcRn receptor in placental tissue and its relationship with IgG levels in term and preterm newborns. American Journal of Reproductive Immunology (New York, N.Y. : 1989). e12972. PMID 29745444 DOI: 10.1111/Aji.12972  0.307
2018 Schwab C, Gabrysch A, Olbrich P, Patiño V, Warnatz K, Wolff D, Hoshino A, Kobayashi M, Imai K, Takagi M, Dybedal I, Haddock JA, Sansom D, Lucena JM, Seidl M, ... ... Blumberg R, et al. Phenotype, penetrance, and treatment of 133 CTLA-4-insufficient individuals. The Journal of Allergy and Clinical Immunology. PMID 29729943 DOI: 10.1016/J.Jaci.2018.02.055  0.356
2018 Blumberg RS, Lillicrap D. Tolerogenic properties of Fc portion of IgG and its relevance to the treatment and management of hemophilia. Blood. PMID 29588277 DOI: 10.1182/Blood-2017-12-822908  0.307
2018 Grevys A, Nilsen J, Sand KMK, Daba MB, Øynebråten I, Bern M, McAdam MB, Foss S, Schlothauer T, Michaelsen TE, Christianson GJ, Roopenian DC, Blumberg RS, Sandlie I, Andersen JT. A human endothelial cell-based recycling assay for screening of FcRn targeted molecules. Nature Communications. 9: 621. PMID 29434196 DOI: 10.1038/S41467-018-03061-X  0.312
2018 Sabatos-Peyton CA, Nevin J, Brock A, Venable JD, Tan DJ, Kassam N, Xu F, Taraszka J, Wesemann L, Pertel T, Acharya N, Klapholz M, Etminan Y, Jiang X, Huang YH, ... Blumberg RS, et al. Blockade of Tim-3 binding to phosphatidylserine and CEACAM1 is a shared feature of anti-Tim-3 antibodies that have functional efficacy. Oncoimmunology. 7: e1385690. PMID 29308307 DOI: 10.1080/2162402X.2017.1385690  0.33
2017 Renz H, Adkins BD, Bartfeld S, Blumberg RS, Farber DL, Garssen J, Ghazal P, Hackam DJ, Marsland BJ, McCoy KD, Penders J, Prinz I, Verhasselt V, von Mutius E, Weiser JN, et al. The neonatal window of opportunity - early priming for life. The Journal of Allergy and Clinical Immunology. PMID 29247715 DOI: 10.1016/J.Jaci.2017.11.019  0.308
2017 Clancy-Thompson E, Ali L, Bruck PT, Exley MA, Blumberg RS, Dranoff G, Dougan M, Dougan SK. IAP Antagonists Enhance Cytokine Production from Mouse and Human iNKT Cells. Cancer Immunology Research. PMID 29187357 DOI: 10.1158/2326-6066.Cir-17-0490  0.653
2017 Nguyen S, Baker K, Padman BS, Patwa R, Dunstan RA, Weston TA, Schlosser K, Bailey B, Lithgow T, Lazarou M, Luque A, Rohwer F, Blumberg RS, Barr JJ. Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers. Mbio. 8. PMID 29162715 DOI: 10.1128/Mbio.01874-17  0.343
2017 Ohsaki A, Venturelli N, Buccigrosso TM, Osganian SK, Lee J, Blumberg RS, Oyoshi MK. Maternal IgG immune complexes induce food allergen-specific tolerance in offspring. The Journal of Experimental Medicine. PMID 29158374 DOI: 10.1084/Jem.20171163  0.369
2017 Zeissig S, Peuker K, Iyer S, Gensollen T, Dougan SK, Olszak T, Kaser A, Blumberg RS. CD1d-Restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28893990 DOI: 10.1073/Pnas.1701428114  0.667
2017 Kaser A, Blumberg RS. The road to Crohn's disease. Science (New York, N.Y.). 357: 976-977. PMID 28883062 DOI: 10.1126/Science.Aao4158  0.356
2017 Hosomi S, Grootjans J, Tschurtschenthaler M, Krupka N, Matute JD, Flak MB, Martinez-Naves E, Gomez Del Moral M, Glickman JN, Ohira M, Lanier LL, Kaser A, Blumberg R. Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation. The Journal of Experimental Medicine. PMID 28747426 DOI: 10.1084/Jem.20162041  0.399
2017 Kim WM, Kaser A, Blumberg RS. A role for oncostatin M in inflammatory bowel disease. Nature Medicine. 23: 535-536. PMID 28475567 DOI: 10.1038/Nm.4338  0.311
2017 Gensollen T, Blumberg RS. Correlation between early-life regulation of the immune system by microbiota and allergy development. The Journal of Allergy and Clinical Immunology. 139: 1084-1091. PMID 28390575 DOI: 10.1016/J.Jaci.2017.02.011  0.317
2017 Ueshima C, Kataoka TR, Takei Y, Hirata M, Sugimoto A, Hirokawa M, Okayama Y, Blumberg RS, Haga H. CEACAM1 long isoform has opposite effects on the growth of human mastocytosis and medullary thyroid carcinoma cells. Cancer Medicine. PMID 28332308 DOI: 10.1002/Cam4.1050  0.353
2017 Pyzik M, Rath T, Kuo TT, Win S, Baker K, Hubbard JJ, Grenha R, Gandhi A, Krämer TD, Mezo AR, Taylor ZS, McDonnell K, Nienaber V, Andersen JT, Mizoguchi A, ... ... Blumberg RS, et al. Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury. Proceedings of the National Academy of Sciences of the United States of America. PMID 28330995 DOI: 10.1073/Pnas.1618291114  0.314
2017 Schrumpf E, Jiang X, Zeissig S, Pollheimer MJ, Anmarkrud JA, Tan C, Exley MA, Karlsen TH, Blumberg RS, Melum E. The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation. Physiological Reports. 5. PMID 28219981 DOI: 10.14814/Phy2.13117  0.345
2017 Tschurtschenthaler M, Adolph TE, Ashcroft JW, Niederreiter L, Bharti R, Saveljeva S, Bhattacharyya J, Flak MB, Shih DQ, Fuhler GM, Parkes M, Kohno K, Iwawaki T, Janneke van der Woude C, Harding HP, ... ... Blumberg RS, et al. Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis. The Journal of Experimental Medicine. PMID 28082357 DOI: 10.1084/Jem.20160791  0.361
2017 Hubbard J, Rath T, Pyzik M, Andersen J, Kim W, Krupka N, Fiebiger E, Turner JR, Glickman J, Lencer WI, Sandlie I, Roopenian D, Baker K, Blumberg RS. Neonatal FC Receptor Cooperates with Classical FC Gamma Receptors to Control Inflammatory Bowel Disease through Regulating Immune Complex Processing Gastroenterology. 152: S614. DOI: 10.1016/S0016-5085(17)32182-0  0.345
2016 Schrumpf E, Kummen M, Valestrand L, Greiner TU, Holm K, Arulampalam V, Reims HM, Baines J, Bäckhed F, Karlsen TH, Blumberg RS, Hov JR, Melum E. The gut microbiota contributes to a mouse model of spontaneous bile duct inflammation. Journal of Hepatology. PMID 27720803 DOI: 10.1016/J.Jhep.2016.09.020  0.353
2016 Nakanishi Y, Reina-Campos M, Nakanishi N, Llado V, Elmen L, Peterson S, Campos A, De SK, Leitges M, Ikeuchi H, Pellecchia M, Blumberg RS, Diaz-Meco MT, Moscat J. Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKCλ/ι. Cell Reports. 16: 3297-310. PMID 27653691 DOI: 10.1016/J.Celrep.2016.08.054  0.396
2016 Zeissig Y, Petersen BS, Franke A, Blumberg RS, Zeissig S. Rare phenotypes in the understanding of autoimmunity. Immunology and Cell Biology. PMID 27562064 DOI: 10.1038/Icb.2016.76  0.31
2016 Aden K, Rehman A, Falk-Paulsen M, Secher T, Kuiper J, Tran F, Pfeuffer S, Sheibani-Tezerji R, Breuer A, Luzius A, Jentzsch M, Häsler R, Billmann-Born S, Will O, Lipinski S, ... ... Blumberg RS, et al. Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation. Cell Reports. PMID 27524624 DOI: 10.1016/J.Celrep.2016.07.054  0.304
2016 Grootjans J, Kaser A, Kaufman RJ, Blumberg RS. The unfolded protein response in immunity and inflammation. Nature Reviews. Immunology. PMID 27346803 DOI: 10.1038/Nri.2016.62  0.372
2016 Gensollen T, Iyer SS, Kasper DL, Blumberg RS. How colonization by microbiota in early life shapes the immune system. Science (New York, N.Y.). 352: 539-44. PMID 27126036 DOI: 10.1126/Science.Aad9378  0.329
2016 Peuker K, Muff S, Wang J, Künzel S, Bosse E, Zeissig Y, Luzzi G, Basic M, Strigli A, Ulbricht A, Kaser A, Arlt A, Chavakis T, van den Brink GR, Schafmayer C, ... ... Blumberg RS, et al. Epithelial calcineurin controls microbiota-dependent intestinal tumor development. Nature Medicine. PMID 27043494 DOI: 10.1038/Nm.4072  0.357
2016 Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, ... ... Blumberg RS, et al. Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature. PMID 26982724 DOI: 10.1038/Nature17421  0.566
2016 Blumberg RS. Environment and Genes: What Is the Interaction? Digestive Diseases (Basel, Switzerland). 34: 20-26. PMID 26982321 DOI: 10.1159/000442920  0.347
2016 Vourtzoumis P, Seth R, Rayes R, Najmeh S, Cools-Lartigue J, Giannias B, Beauchemin N, Rousseau S, Blumberg R, Spicer JD, Ferri LE. Abstract LB-078: The role of CEACAM1 in neutrophil extracellular Trap mediated cancer metastasis Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-078  0.331
2016 Valestrand L, Berntsen N, Schrumpf E, Karlsen T, Blumberg R, Melum E. Lipid Antigens in Bile from Patients with Liver Diseases Activate Natural Killer T Cells Journal of Hepatology. 64: S632. DOI: 10.1016/S0168-8278(16)01172-7  0.365
2016 Li Y, Chen H, Weiner GJ, Blumberg RS, Blazar BR, Elliott DE, Ince MN. 191 Interleukin 4 Is Critical in Helminth-Induced Regulatory T-Cell Expansion and Suppression of Colitis in a Graft Versus Host Disease Model Gastroenterology. 150: S50. DOI: 10.1016/S0016-5085(16)30292-X  0.356
2015 Krishnamoorthy S, Liu T, Drager D, Patarroyo-White S, Chhabra ES, Peters R, Josephson N, Lillicrap D, Blumberg RS, Pierce GF, Jiang H. Recombinant factor VIII Fc (rFVIIIFc) fusion protein reduces immunogenicity and induces tolerance in hemophilia A mice. Cellular Immunology. PMID 26775174 DOI: 10.1016/J.Cellimm.2015.12.008  0.399
2015 Grootjans J, Hosomi S, Blumberg RS. Leukotrienes and the other airway: Celiac disease and asthma collide. The Journal of Experimental Medicine. 212: 1485. PMID 26392429 DOI: 10.1084/Jem.21210Insight4  0.349
2015 Dowds CM, Blumberg RS, Zeissig S. Control of intestinal homeostasis through crosstalk between natural killer T cells and the intestinal microbiota. Clinical Immunology (Orlando, Fla.). 159: 128-33. PMID 25988859 DOI: 10.1016/J.Clim.2015.05.008  0.412
2015 Pyzik M, Rath T, Lencer WI, Baker K, Blumberg RS. FcRn: The Architect Behind the Immune and Nonimmune Functions of IgG and Albumin. Journal of Immunology (Baltimore, Md. : 1950). 194: 4595-603. PMID 25934922 DOI: 10.4049/Jimmunol.1403014  0.341
2015 Schrumpf E, Tan C, Karlsen TH, Sponheim J, Björkström NK, Sundnes O, Alfsnes K, Kaser A, Jefferson DM, Ueno Y, Eide TJ, Haraldsen G, Zeissig S, Exley MA, Blumberg RS, et al. The biliary epithelium presents antigens to and activates natural killer T cells. Hepatology (Baltimore, Md.). PMID 25855031 DOI: 10.1002/Hep.27840  0.426
2015 Platzer B, Elpek KG, Cremasco V, Baker K, Stout MM, Schultz C, Dehlink E, Shade KT, Anthony RM, Blumberg RS, Turley SJ, Fiebiger E. IgE/FcεRI-Mediated Antigen Cross-Presentation by Dendritic Cells Enhances Anti-Tumor Immune Responses. Cell Reports. PMID 25753415 DOI: 10.1016/J.Celrep.2015.02.015  0.379
2015 Arabzadeh A, Dupaul-Chicoine J, Breton V, Haftchenary S, Yumeen S, Turbide C, Saleh M, McGregor K, Greenwood CM, Akavia UD, Blumberg RS, Gunning PT, Beauchemin N. Carcinoembryonic Antigen Cell Adhesion Molecule 1 long isoform modulates malignancy of poorly differentiated colon cancer cells. Gut. PMID 25666195 DOI: 10.1136/Gutjnl-2014-308781  0.322
2015 Bundhoo A, Paveglio S, Rafti E, Dhongade A, Blumberg RS, Matson AP. Evidence that FcRn mediates the transplacental passage of maternal IgE in the form of IgG anti-IgE/IgE immune complexes. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 45: 1085-98. PMID 25652137 DOI: 10.1111/Cea.12508  0.312
2015 Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, ... ... Blumberg RS, et al. CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature. 517: 386-90. PMID 25363763 DOI: 10.1038/Nature13848  0.677
2015 Platzer B, Baker K, Vera MP, Singer K, Panduro M, Lexmond WS, Turner D, Vargas SO, Kinet JP, Maurer D, Baron RM, Blumberg RS, Fiebiger E. Dendritic cell-bound IgE functions to restrain allergic inflammation at mucosal sites. Mucosal Immunology. 8: 516-32. PMID 25227985 DOI: 10.1038/Mi.2014.85  0.412
2015 Rath T, Baker K, Dumont JA, Peters RT, Jiang H, Qiao SW, Lencer WI, Pierce GF, Blumberg RS. Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeutics. Critical Reviews in Biotechnology. 35: 235-54. PMID 24156398 DOI: 10.3109/07388551.2013.834293  0.317
2015 Schrumpf E, Jiang X, Zeissig S, Pollheimer M, Anmarkrud J, Tan C, Exley M, Karlsen T, Blumberg R, Melum E. P1190 : The role of NKT cells in a mouse model (NOD.C3C4) with spontaneous bile duct inflammation Journal of Hepatology. 62: S801. DOI: 10.1016/S0168-8278(15)31386-6  0.332
2015 Zeissig S, Mayer L, Blumberg RS. Role of Epithelial Cells in Antigen Presentation Mucosal Immunology: Fourth Edition. 1: 557-570. DOI: 10.1016/B978-0-12-415847-4.00027-6  0.305
2014 Rath T, Baker K, Pyzik M, Blumberg RS. Regulation of immune responses by the neonatal fc receptor and its therapeutic implications. Frontiers in Immunology. 5: 664. PMID 25601863 DOI: 10.3389/Fimmu.2014.00664  0.404
2014 Zeissig S, Petersen BS, Tomczak M, Melum E, Huc-Claustre E, Dougan SK, Laerdahl JK, Stade B, Forster M, Schreiber S, Weir D, Leichtner AM, Franke A, Blumberg RS. Early-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4. Gut. PMID 25367873 DOI: 10.1136/Gutjnl-2014-308541  0.6
2014 Baker K, Rath T, Pyzik M, Blumberg RS. Neonatal Fc receptors for IgG drive CD8(+) T cell-mediated anti-cancer immunosurveillance at tolerogenic mucosal sites. Oncoimmunology. 3: e27844. PMID 25339998 DOI: 10.4161/Onci.27844  0.386
2014 Baker K, Rath T, Pyzik M, Blumberg RS. The Role of FcRn in Antigen Presentation. Frontiers in Immunology. 5: 408. PMID 25221553 DOI: 10.3389/Fimmu.2014.00408  0.447
2014 Ko SY, Pegu A, Rudicell RS, Yang ZY, Joyce MG, Chen X, Wang K, Bao S, Kraemer TD, Rath T, Zeng M, Schmidt SD, Todd JP, Penzak SR, Saunders KO, ... ... Blumberg RS, et al. Enhanced neonatal Fc receptor function improves protection against primate SHIV infection. Nature. 514: 642-5. PMID 25119033 DOI: 10.1038/Nature13612  0.338
2014 Zeissig S, Blumberg RS. Commensal microbial regulation of natural killer T cells at the frontiers of the mucosal immune system. Febs Letters. 588: 4188-94. PMID 24983499 DOI: 10.1016/J.Febslet.2014.06.042  0.429
2014 Olszak T, Neves JF, Dowds CM, Baker K, Glickman J, Davidson NO, Lin CS, Jobin C, Brand S, Sotlar K, Wada K, Katayama K, Nakajima A, Mizuguchi H, Kawasaki K, ... ... Blumberg RS, et al. Protective mucosal immunity mediated by epithelial CD1d and IL-10. Nature. 509: 497-502. PMID 24717441 DOI: 10.1038/Nature13150  0.421
2014 Kaser A, Blumberg RS. Cell biology: Stressful genetics in Crohn's disease. Nature. 506: 441-2. PMID 24553137 DOI: 10.1038/Nature13060  0.318
2014 Afrazi A, Branca MF, Sodhi CP, Good M, Yamaguchi Y, Egan CE, Lu P, Jia H, Shaffiey S, Lin J, Ma C, Vincent G, Prindle T, Weyandt S, Neal MD, ... ... Blumberg R, et al. Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis. The Journal of Biological Chemistry. 289: 9584-99. PMID 24519940 DOI: 10.1074/Jbc.M113.526517  0.32
2014 Lexmond WS, Neves JF, Nurko S, Olszak T, Exley MA, Blumberg RS, Fiebiger E. Involvement of the iNKT cell pathway is associated with early-onset eosinophilic esophagitis and response to allergen avoidance therapy. The American Journal of Gastroenterology. 109: 646-57. PMID 24513807 DOI: 10.1038/Ajg.2014.12  0.374
2014 Armitage CW, O'Meara CP, Harvie MC, Timms P, Blumberg RS, Beagley KW. Divergent outcomes following transcytosis of IgG targeting intracellular and extracellular chlamydial antigens. Immunology and Cell Biology. 92: 417-26. PMID 24445600 DOI: 10.1038/Icb.2013.110  0.348
2014 An D, Oh SF, Olszak T, Neves JF, Avci FY, Erturk-Hasdemir D, Lu X, Zeissig S, Blumberg RS, Kasper DL. Sphingolipids from a symbiotic microbe regulate homeostasis of host intestinal natural killer T cells. Cell. 156: 123-33. PMID 24439373 DOI: 10.1016/J.Cell.2013.11.042  0.446
2014 Dowds CM, Kornell SC, Blumberg RS, Zeissig S. Lipid antigens in immunity. Biological Chemistry. 395: 61-81. PMID 23999493 DOI: 10.1515/Hsz-2013-0220  0.379
2014 Schrumpf E, Tan C, Karlsen T, Sponheim J, Jefferson D, Zeissig S, Exley M, Blumberg R, Melum E. P354 CHOLANGIOCYTES FROM PATIENTS WITH PRIMARY SCLEROSING CHOLANGITIS EXPRESS CD1D AND HUMAN CHOLANGIOCYTES PRESENT ANTIGENS TO NATURAL KILLER T CELLS Journal of Hepatology. 60: S185. DOI: 10.1016/S0168-8278(14)60516-X  0.381
2014 Olszak T, Neves JF, Dowds MC, Baker K, Glickman J, Davidson N, Jobin C, Brand S, Muller W, Wada K, Katayama K, Nakajima A, Mizuguchi H, Kawasaki K, Nagata K, ... ... Blumberg RS, et al. 406 A Self-Reinforcing Pathway of Protective Mucosal Immunity Mediated by Epithelial CD1d Gastroenterology. 146: S-87. DOI: 10.1016/S0016-5085(14)60314-0  0.307
2013 Baker K, Rath T, Flak MB, Arthur JC, Chen Z, Glickman JN, Zlobec I, Karamitopoulou E, Stachler MD, Odze RD, Lencer WI, Jobin C, Blumberg RS. Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer. Immunity. 39: 1095-107. PMID 24290911 DOI: 10.1016/J.Immuni.2013.11.003  0.441
2013 Zeissig S, Blumberg RS. Commensal microbiota and NKT cells in the control of inflammatory diseases at mucosal surfaces. Current Opinion in Immunology. 25: 690-6. PMID 24210255 DOI: 10.1016/J.Coi.2013.09.012  0.448
2013 Adolph TE, Tomczak MF, Niederreiter L, Ko HJ, Böck J, Martinez-Naves E, Glickman JN, Tschurtschenthaler M, Hartwig J, Hosomi S, Flak MB, Cusick JL, Kohno K, Iwawaki T, Billmann-Born S, ... ... Blumberg RS, et al. Paneth cells as a site of origin for intestinal inflammation. Nature. 503: 272-6. PMID 24089213 DOI: 10.1038/Nature12599  0.405
2013 Niederreiter L, Fritz TM, Adolph TE, Krismer AM, Offner FA, Tschurtschenthaler M, Flak MB, Hosomi S, Tomczak MF, Kaneider NC, Sarcevic E, Kempster SL, Raine T, Esser D, Rosenstiel P, ... ... Blumberg RS, et al. ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells. The Journal of Experimental Medicine. 210: 2041-56. PMID 24043762 DOI: 10.1084/Jem.20122341  0.365
2013 Weflen AW, Baier N, Tang QJ, Van den Hof M, Blumberg RS, Lencer WI, Massol RH. Multivalent immune complexes divert FcRn to lysosomes by exclusion from recycling sorting tubules. Molecular Biology of the Cell. 24: 2398-405. PMID 23741050 DOI: 10.1091/Mbc.E13-04-0174  0.352
2013 Garn H, Neves JF, Blumberg RS, Renz H. Effect of barrier microbes on organ-based inflammation. The Journal of Allergy and Clinical Immunology. 131: 1465-78. PMID 23726530 DOI: 10.1016/J.Jaci.2013.04.031  0.343
2013 Hosomi S, Chen Z, Baker K, Chen L, Huang YH, Olszak T, Zeissig S, Wang JH, Mandelboim O, Beauchemin N, Lanier LL, Blumberg RS. CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling. European Journal of Immunology. 43: 2473-83. PMID 23696226 DOI: 10.1002/Eji.201242676  0.4
2013 Kaser A, Blumberg RS. Introduction: the unfolded protein response's role in disease pathophysiology. Seminars in Immunopathology. 35: 255-7. PMID 23609501 DOI: 10.1007/S00281-013-0379-3  0.33
2013 Kaser A, Adolph TE, Blumberg RS. The unfolded protein response and gastrointestinal disease. Seminars in Immunopathology. 35: 307-19. PMID 23588234 DOI: 10.1007/S00281-013-0377-5  0.342
2013 Zeissig S, Olszak T, Melum E, Blumberg RS. Analyzing antigen recognition by Natural Killer T cells. Methods in Molecular Biology (Clifton, N.J.). 960: 557-72. PMID 23329514 DOI: 10.1007/978-1-62703-218-6_41  0.463
2013 Rath T, Kuo TT, Baker K, Qiao SW, Kobayashi K, Yoshida M, Roopenian D, Fiebiger E, Lencer WI, Blumberg RS. The immunologic functions of the neonatal Fc receptor for IgG. Journal of Clinical Immunology. 33: S9-17. PMID 22948741 DOI: 10.1007/S10875-012-9768-Y  0.386
2013 Baker K, Rath T, Lencer WI, Fiebiger E, Blumberg RS. Cross-presentation of IgG-containing immune complexes. Cellular and Molecular Life Sciences : Cmls. 70: 1319-34. PMID 22847331 DOI: 10.1007/S00018-012-1100-8  0.461
2013 Nishida A, Nagahama K, Imaeda H, Lau CW, Kobayashi T, Hisamatsu T, Mizoguchi E, Hibi T, Andoh A, Blumberg RS, Mizoguchi A. Sa1775 T Cell-Specific Colitis-Associated Glycome Gastroenterology. 144: S-303. DOI: 10.1016/S0016-5085(13)61086-0  0.38
2013 Niederreiter L, Fritz TM, Adolph T, Offner FA, Hosomi S, Tomczak M, Tschurtschenthaler M, Kempster SL, Raine T, Tilg H, Blumberg RS, Kaser A. 154 ER Stress Transcription Factor XBP1 Suppresses Intestinal Tumorigenesis Gastroenterology. 144: S-35. DOI: 10.1016/S0016-5085(13)60125-0  0.354
2012 Nishida A, Nagahama K, Imaeda H, Ogawa A, Lau CW, Kobayashi T, Hisamatsu T, Preffer FI, Mizoguchi E, Ikeuchi H, Hibi T, Fukuda M, Andoh A, Blumberg RS, Mizoguchi A. Inducible colitis-associated glycome capable of stimulating the proliferation of memory CD4+ T cells. The Journal of Experimental Medicine. 209: 2383-94. PMID 23209314 DOI: 10.1084/Jem.20112631  0.413
2012 Chen L, Chen Z, Baker K, Halvorsen EM, da Cunha AP, Flak MB, Gerber G, Huang YH, Hosomi S, Arthur JC, Dery KJ, Nagaishi T, Beauchemin N, Holmes KV, Ho JW, ... ... Blumberg RS, et al. The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction. Immunity. 37: 930-46. PMID 23123061 DOI: 10.1016/J.Immuni.2012.07.016  0.459
2012 Adolph TE, Niederreiter L, Blumberg RS, Kaser A. Endoplasmic reticulum stress and inflammation. Digestive Diseases (Basel, Switzerland). 30: 341-6. PMID 22796794 DOI: 10.1159/000338121  0.35
2012 Zeissig S, Murata K, Sweet L, Publicover J, Hu Z, Kaser A, Bosse E, Iqbal J, Hussain MM, Balschun K, Röcken C, Arlt A, Günther R, Hampe J, Schreiber S, ... ... Blumberg RS, et al. Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity. Nature Medicine. 18: 1060-8. PMID 22706385 DOI: 10.1038/Nm.2811  0.38
2012 Mayer L, Kaser A, Blumberg RS. Dead on arrival: understanding the failure of CTLA4-immunoglobulin therapy in inflammatory bowel disease. Gastroenterology. 143: 13-7. PMID 22626501 DOI: 10.1053/J.Gastro.2012.05.015  0.452
2012 Olszak T, An D, Zeissig S, Vera MP, Richter J, Franke A, Glickman JN, Siebert R, Baron RM, Kasper DL, Blumberg RS. Microbial exposure during early life has persistent effects on natural killer T cell function. Science (New York, N.Y.). 336: 489-93. PMID 22442383 DOI: 10.1126/Science.1219328  0.396
2012 Zeissig S, Blumberg RS. Primary immunodeficiency associated with defects in CD1 and CD1-restricted T cells. Annals of the New York Academy of Sciences. 1250: 14-24. PMID 22276638 DOI: 10.1111/J.1749-6632.2011.06380.X  0.448
2012 Hamilton MJ, Snapper SB, Blumberg RS. Update on biologic pathways in inflammatory bowel disease and their therapeutic relevance. Journal of Gastroenterology. 47: 1-8. PMID 22215058 DOI: 10.1007/S00535-011-0521-8  0.33
2012 Diegelmann J, Olszak T, Göke B, Blumberg RS, Brand S. A novel role for interleukin-27 (IL-27) as mediator of intestinal epithelial barrier protection mediated via differential signal transducer and activator of transcription (STAT) protein signaling and induction of antibacterial and anti-inflammatory proteins. The Journal of Biological Chemistry. 287: 286-98. PMID 22069308 DOI: 10.1074/Jbc.M111.294355  0.324
2012 Zeissig S, Murata K, Sweet L, Publicover J, Hu Z, Kaser A, Arlt A, Günther R, Hampe J, Schreiber S, Baron J, Moody DB, Liang TJ, Blumberg RS. 742 Hepatitis B Virus Infection Leads to Alterations in the Repertoire of Self Lipid Antigens Presented by Hepatocytes and is Associated With Direct and Indirect Activation of Natural Killer T Cells Gastroenterology. 142: S-927. DOI: 10.1016/S0016-5085(12)63596-3  0.342
2012 Nishida A, Lau CW, Kobayashi T, Hisamatsu T, Mizoguchi E, Hibi T, Andoh A, Blumberg RS, Mizoguchi A. 1072 Colitis-Associated Glycome Promoting the Expansion of Memory CD4+ T Cells Gastroenterology. 142: S-191. DOI: 10.1016/S0016-5085(12)60715-X  0.328
2011 Chen Z, Chen L, Baker K, Olszak T, Zeissig S, Huang YH, Kuo TT, Mandelboim O, Beauchemin N, Lanier LL, Blumberg RS. CEACAM1 dampens antitumor immunity by down-regulating NKG2D ligand expression on tumor cells. The Journal of Experimental Medicine. 208: 2633-40. PMID 22143889 DOI: 10.1084/Jem.20102575  0.336
2011 Kaser A, Niederreiter L, Blumberg RS. Genetically determined epithelial dysfunction and its consequences for microflora-host interactions. Cellular and Molecular Life Sciences : Cmls. 68: 3643-9. PMID 21984606 DOI: 10.1007/S00018-011-0827-Y  0.392
2011 Fredenburgh LE, Velandia MM, Ma J, Olszak T, Cernadas M, Englert JA, Chung SW, Liu X, Begay C, Padera RF, Blumberg RS, Walsh SR, Baron RM, Perrella MA. Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis. Journal of Immunology (Baltimore, Md. : 1950). 187: 5255-67. PMID 21967897 DOI: 10.4049/Jimmunol.1101186  0.343
2011 Kaser A, Flak MB, Tomczak MF, Blumberg RS. The unfolded protein response and its role in intestinal homeostasis and inflammation. Experimental Cell Research. 317: 2772-9. PMID 21821022 DOI: 10.1016/J.Yexcr.2011.07.008  0.387
2011 Wirtz S, Billmeier U, Mchedlidze T, Blumberg RS, Neurath MF. Interleukin-35 mediates mucosal immune responses that protect against T-cell-dependent colitis. Gastroenterology. 141: 1875-86. PMID 21820391 DOI: 10.1053/J.Gastro.2011.07.040  0.34
2011 Baker K, Qiao SW, Kuo TT, Aveson VG, Platzer B, Andersen JT, Sandlie I, Chen Z, de Haar C, Lencer WI, Fiebiger E, Blumberg RS. Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 9927-32. PMID 21628593 DOI: 10.1073/Pnas.1019037108  0.397
2011 Kaser A, Blumberg RS. Autophagy, microbial sensing, endoplasmic reticulum stress, and epithelial function in inflammatory bowel disease. Gastroenterology. 140: 1738-47. PMID 21530740 DOI: 10.1053/J.Gastro.2011.02.048  0.408
2011 Kaser A, Blumberg RS. Lessons from type I interferons in ulcerative colitis. Gut. 60: 430-1. PMID 21266724 DOI: 10.1136/Gut.2010.229138  0.46
2011 Fritz T, Niederreiter L, Adolph T, Blumberg RS, Kaser A. Crohn's disease: NOD2, autophagy and ER stress converge. Gut. 60: 1580-8. PMID 21252204 DOI: 10.1136/Gut.2009.206466  0.337
2011 Hamilton MJ, Sinnamon MJ, Lyng GD, Glickman JN, Wang X, Xing W, Krilis SA, Blumberg RS, Adachi R, Lee DM, Stevens RL. Essential role for mast cell tryptase in acute experimental colitis. Proceedings of the National Academy of Sciences of the United States of America. 108: 290-5. PMID 21173247 DOI: 10.1073/Pnas.1005758108  0.318
2011 Kaser A, Tomczak M, Blumberg RS. "ER stress(ed out)!": Paneth cells and ischemia-reperfusion injury of the small intestine. Gastroenterology. 140: 393-6. PMID 21172333 DOI: 10.1053/J.Gastro.2010.12.015  0.362
2011 An D, Olszak T, Zeissig S, Blumberg R, Kasper D. Early life exposure to microbiota has persistent effects on colonic lamina propria iNKT cells and colitis Inflammatory Bowel Diseases. 17: S70. DOI: 10.1097/00054725-201112002-00227  0.304
2011 Zeissig S, Murata K, Hu Z, Kaser A, Dougan S, Bosse E, Scapa E, Cohen D, Arlt A, Franke A, Schreiber S, Liang T, Blumberg R. Hepatitis B-Virus-induzierte hepatozytäre Lipidantigene aktivieren Natürliche Killer T-Zellen und sind von zentraler Bedeutung für die antivirale Immunantwort Zeitschrift FüR Gastroenterologie. 49. DOI: 10.1055/S-0031-1285206  0.575
2011 Zeissig S, Murata K, Hu Z, Kaser A, Dougan SK, Bosse E, Scapa EF, Cohen DE, Arlt A, Franke A, Schreiber S, Liang TJ, Blumberg RS. Early Alterations in Endogenous Hepatocyte Lipid Antigens in Hepatitis B Virus Infection Are Associated With CD1D-Restricted Natural Killer T Cell Activation and Viral Clearance Gastroenterology. 140: S-886. DOI: 10.1016/S0016-5085(11)63685-8  0.62
2011 Tomczak M, Ko H, Martinez-Naves E, Hagen SJ, Kaser A, Blumberg RS. Conditional XBP1 Deletion Within the Intestinal Epithelial Cells Results in Activation of Autophagy in Paneth Cells Gastroenterology. 140: S-172. DOI: 10.1016/S0016-5085(11)60695-1  0.376
2010 Kaser A, Zeissig S, Blumberg RS. Genes and environment: how will our concepts on the pathophysiology of IBD develop in the future? Digestive Diseases (Basel, Switzerland). 28: 395-405. PMID 20926863 DOI: 10.1159/000320393  0.346
2010 Kuo TT, Baker K, Yoshida M, Qiao SW, Aveson VG, Lencer WI, Blumberg RS. Neonatal Fc receptor: from immunity to therapeutics. Journal of Clinical Immunology. 30: 777-89. PMID 20886282 DOI: 10.1007/S10875-010-9468-4  0.396
2010 Dougan M, Dougan S, Slisz J, Firestone B, Vanneman M, Draganov D, Goyal G, Li W, Neuberg D, Blumberg R, Hacohen N, Porter D, Zawel L, Dranoff G. IAP inhibitors enhance co-stimulation to promote tumor immunity. The Journal of Experimental Medicine. 207: 2195-206. PMID 20837698 DOI: 10.1084/Jem.20101123  0.65
2010 Zeissig S, Dougan SK, Barral DC, Junker Y, Chen Z, Kaser A, Ho M, Mandel H, McIntyre A, Kennedy SM, Painter GF, Veerapen N, Besra GS, Cerundolo V, Yue S, ... ... Blumberg RS, et al. Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function. The Journal of Clinical Investigation. 120: 2889-99. PMID 20592474 DOI: 10.1172/Jci42703  0.643
2010 Kaser A, Martínez-Naves E, Blumberg RS. Endoplasmic reticulum stress: implications for inflammatory bowel disease pathogenesis. Current Opinion in Gastroenterology. 26: 318-26. PMID 20495455 DOI: 10.1097/Mog.0B013E32833A9Ff1  0.352
2010 Kaser A, Blumberg RS. Survive an innate immune response through XBP1. Cell Research. 20: 506-7. PMID 20436510 DOI: 10.1038/Cr.2010.61  0.396
2010 Nakata K, Kobayashi K, Ishikawa Y, Yamamoto M, Funada Y, Kotani Y, Blumberg RS, Karasuyama H, Yoshida M, Nishimura Y. The transfer of maternal antigen-specific IgG regulates the development of allergic airway inflammation early in life in an FcRn-dependent manner. Biochemical and Biophysical Research Communications. 395: 238-43. PMID 20362552 DOI: 10.1016/J.Bbrc.2010.03.170  0.36
2010 Shiomi H, Masuda A, Nishiumi S, Nishida M, Takagawa T, Shiomi Y, Kutsumi H, Blumberg RS, Azuma T, Yoshida M. Gamma interferon produced by antigen-specific CD4+ T cells regulates the mucosal immune responses to Citrobacter rodentium infection. Infection and Immunity. 78: 2653-66. PMID 20351140 DOI: 10.1128/Iai.01343-09  0.43
2010 Inaba K, Fukazawa Y, Matsuda K, Himeno A, Matsuyama M, Ibuki K, Miura Y, Koyanagi Y, Nakajima A, Blumberg RS, Takahashi H, Hayami M, Igarashi T, Miura T. Small intestine CD4+ cell reduction and enteropathy in simian/human immunodeficiency virus KS661-infected rhesus macaques in the presence of low viral load. The Journal of General Virology. 91: 773-81. PMID 19889928 DOI: 10.1099/Vir.0.017368-0  0.324
2010 Kaser A, Blumberg RS. Endoplasmic reticulum stress and intestinal inflammation. Mucosal Immunology. 3: 11-6. PMID 19865077 DOI: 10.1038/Mi.2009.122  0.344
2010 Ishida T, Yoshida M, Arita M, Nishitani Y, Nishiumi S, Masuda A, Mizuno S, Takagawa T, Morita Y, Kutsumi H, Inokuchi H, Serhan CN, Blumberg RS, Azuma T. Resolvin E1, an endogenous lipid mediator derived from eicosapentaenoic acid, prevents dextran sulfate sodium-induced colitis. Inflammatory Bowel Diseases. 16: 87-95. PMID 19572372 DOI: 10.1002/Ibd.21029  0.39
2010 Chen Z, Chen L, Nagaishi T, Nakajima A, Iijima H, Blumberg RS. Regulation of lymphocyte function by carcinoembryonic antigen adhesion molecule 1 (LL3-2) International Immunology. 22: iii7-iii7. DOI: 10.1093/Intimm/Dxq202  0.342
2010 Baker K, Lencer WI, Blumberg RS. Beyond IgA: The mucosal immunoglobulin alphabet Mucosal Immunology. 3: 324-325. DOI: 10.1038/Mi.2010.15  0.344
2010 Olszak T, Zeissig S, Kaser A, Davidson NO, Blumberg RS. 847s Intestinal Microsomal Triglyceride Transfer Protein (MTP) Regulates CD1d Function on the Intestinal Epithelium and Protects From Mortality in the Oxazolone Model Gastroenterology. 138: S-114. DOI: 10.1016/S0016-5085(10)60525-2  0.305
2009 Blumberg RS. Inflammation in the intestinal tract: pathogenesis and treatment. Digestive Diseases (Basel, Switzerland). 27: 455-64. PMID 19897960 DOI: 10.1159/000235851  0.444
2009 Kobayashi K, Qiao SW, Yoshida M, Baker K, Lencer WI, Blumberg RS. An FcRn-dependent role for anti-flagellin immunoglobulin G in pathogenesis of colitis in mice. Gastroenterology. 137: 1746-56.e1. PMID 19664634 DOI: 10.1053/J.Gastro.2009.07.059  0.372
2009 Liu J, Divoux A, Sun J, Zhang J, Clément K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, et al. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nature Medicine. 15: 940-5. PMID 19633655 DOI: 10.1038/Nm.1994  0.336
2009 Baker K, Qiao SW, Kuo T, Kobayashi K, Yoshida M, Lencer WI, Blumberg RS. Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn. Seminars in Immunopathology. 31: 223-36. PMID 19495758 DOI: 10.1007/S00281-009-0160-9  0.384
2009 Tzaban S, Massol RH, Yen E, Hamman W, Frank SR, Lapierre LA, Hansen SH, Goldenring JR, Blumberg RS, Lencer WI. The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity. The Journal of Cell Biology. 185: 673-84. PMID 19451275 DOI: 10.1083/Jcb.200809122  0.336
2009 Nieuwenhuis EE, Matsumoto T, Lindenbergh D, Willemsen R, Kaser A, Simons-Oosterhuis Y, Brugman S, Yamaguchi K, Ishikawa H, Aiba Y, Koga Y, Samsom JN, Oshima K, Kikuchi M, Escher JC, ... ... Blumberg RS, et al. Cd1d-dependent regulation of bacterial colonization in the intestine of mice. The Journal of Clinical Investigation. 119: 1241-50. PMID 19349688 DOI: 10.1172/Jci36509  0.378
2009 Qiao SW, Sollid LM, Blumberg RS. Antigen presentation in celiac disease. Current Opinion in Immunology. 21: 111-7. PMID 19342211 DOI: 10.1016/J.Coi.2009.03.004  0.337
2009 Masuda A, Yoshida M, Shiomi H, Morita Y, Kutsumi H, Inokuchi H, Mizuno S, Nakamura A, Takai T, Blumberg RS, Azuma T. Role of Fc Receptors as a therapeutic target. Inflammation & Allergy Drug Targets. 8: 80-6. PMID 19275696 DOI: 10.2174/187152809787582525  0.355
2009 Kaser A, Blumberg RS. Endoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel disease. Seminars in Immunology. 21: 156-63. PMID 19237300 DOI: 10.1016/J.Smim.2009.01.001  0.312
2009 Kuo TT, de Muinck EJ, Claypool SM, Yoshida M, Nagaishi T, Aveson VG, Lencer WI, Blumberg RS. N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG. The Journal of Biological Chemistry. 284: 8292-300. PMID 19164298 DOI: 10.1074/Jbc.M805877200  0.65
2009 Takamiya R, Hung CC, Hall SR, Fukunaga K, Nagaishi T, Maeno T, Owen C, Macias AA, Fredenburgh LE, Ishizaka A, Blumberg RS, Baron RM, Perrella MA. High-mobility group box 1 contributes to lethality of endotoxemia in heme oxygenase-1-deficient mice. American Journal of Respiratory Cell and Molecular Biology. 41: 129-35. PMID 19097991 DOI: 10.1165/Rcmb.2008-0331Oc  0.307
2009 Blumberg R. What are innate and acquired immunity, and why are they important in IBD? Inflammatory Bowel Diseases. S93-4. PMID 18816702 DOI: 10.1002/Ibd.20689  0.316
2009 Hamilton M, Sinnamon M, Glickman J, Krilis S, Blumberg R, Lee D, Adachi R, Stevens R. Mast cell-restricted Tryptases are essential in a Mouse Model of Inflammatory Bowel Disease Inflammatory Bowel Diseases. 15: S53-S54. DOI: 10.1097/00054725-200912002-00167  0.35
2009 Zeissig S, Blumberg RS. Immunity Against Mucosal Pathogens Gastroenterology. 137: 1533. DOI: 10.1053/J.Gastro.2009.08.037  0.301
2009 Zeissig S, Kaser A, Dougan SK, Scapa EF, Cohen DE, Blumberg RS. T1701 Microsomal Triglyceride Transfer Protein Regulates CD1D-Restricted Antigen Presentation of Hepatocytes and Controls NKT Cell Homeostasis via CD1D-Mediated Apoptosis Gastroenterology. 136: A-561. DOI: 10.1016/S0016-5085(09)62582-8  0.618
2009 Zeissig S, Dougan SK, Junker Y, Chen Z, Chen X, Kennedy S, Ho MM, Mandel H, Yue SC, Gumperz JE, Exley MA, Davidson NO, Blumberg RS. 706 Mutations in the Microsomal Triglyceride Transfer Protein Lead to a Defect in CD1D-Restricted Antigen Presentation and Impaired Activation of Natural Killer T Cells in Patients with Abetalipoproteinemia Gastroenterology. 136: A-111. DOI: 10.1016/S0016-5085(09)60501-1  0.626
2009 Niederreiter L, Zeissig S, Tilg H, Blumberg RS, Kaser A. 497 ER Stress Transcription Factor XBP1 Regulates NfκB Activation in Intestinal Epithelial Cells Gastroenterology. 136: A-81. DOI: 10.1016/S0016-5085(09)60363-2  0.378
2009 Vignali DA, Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, Vignali KM, Cross R, Sehy D, Blumberg RS, Henderson AL, Chaturvedi V, Turk MJ. IL-35 and regulatory T cell function Cytokine. 48: 5. DOI: 10.1016/J.Cyto.2009.07.023  0.33
2008 Nagaishi T, Chen Z, Chen L, Iijima H, Nakajima A, Blumberg RS. CEACAM1 and the regulation of mucosal inflammation. Mucosal Immunology. 1: S39-42. PMID 19079227 DOI: 10.1038/Mi.2008.50  0.457
2008 Zhou D, Medoff BD, Chen L, Li L, Zhang XF, Praskova M, Liu M, Landry A, Blumberg RS, Boussiotis VA, Xavier R, Avruch J. The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naïve T cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 20321-6. PMID 19073936 DOI: 10.1073/Pnas.0810773105  0.404
2008 Kaser A, Blumberg RS. Paneth cells and inflammation dance together in Crohn's disease. Cell Research. 18: 1160-2. PMID 19043437 DOI: 10.1038/Cr.2008.312  0.365
2008 Sauer KA, Maxeiner JH, Karwot R, Scholtes P, Lehr HA, Birkenbach M, Blumberg RS, Finotto S. Immunosurveillance of lung melanoma metastasis in EBI-3-deficient mice mediated by CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 6148-57. PMID 18941205 DOI: 10.4049/Jimmunol.181.9.6148  0.367
2008 Kaser A, Lee AH, Franke A, Glickman JN, Zeissig S, Tilg H, Nieuwenhuis EE, Higgins DE, Schreiber S, Glimcher LH, Blumberg RS. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell. 134: 743-56. PMID 18775308 DOI: 10.1016/J.Cell.2008.07.021  0.392
2008 Kaser A, Hava DL, Dougan SK, Chen Z, Zeissig S, Brenner MB, Blumberg RS. Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules. European Journal of Immunology. 38: 2351-9. PMID 18624350 DOI: 10.1002/Eji.200738102  0.655
2008 Kaser A, Blumberg RS. Adaptive immunity in inflammatory bowel disease: state of the art. Current Opinion in Gastroenterology. 24: 455-61. PMID 18622159 DOI: 10.1097/Mog.0B013E328304D60D  0.451
2008 Qiao SW, Kobayashi K, Johansen FE, Sollid LM, Andersen JT, Milford E, Roopenian DC, Lencer WI, Blumberg RS. Dependence of antibody-mediated presentation of antigen on FcRn. Proceedings of the National Academy of Sciences of the United States of America. 105: 9337-42. PMID 18599440 DOI: 10.1073/Pnas.0801717105  0.386
2008 Tachibana M, Wada K, Katayama K, Kamisaki Y, Maeyama K, Kadowaki T, Blumberg RS, Nakajima A. Activation of peroxisome proliferator-activated receptor gamma suppresses mast cell maturation involved in allergic diseases. Allergy. 63: 1136-47. PMID 18547288 DOI: 10.1111/J.1398-9995.2008.01677.X  0.391
2008 Chen Z, Chen L, Qiao SW, Nagaishi T, Blumberg RS. Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits proximal TCR signaling by targeting ZAP-70. Journal of Immunology (Baltimore, Md. : 1950). 180: 6085-93. PMID 18424730 DOI: 10.4049/Jimmunol.180.9.6085  0.382
2008 Fujisawa T, Nakajima A, Fujisawa N, Takahashi H, Ikeda I, Tomimoto A, Yonemitsu K, Nakajima N, Kudo C, Wada K, Kubota N, Terauchi Y, Kadowaki T, Nakagama H, Blumberg RS. Peroxisome proliferator-activated receptor gamma (PPARgamma) suppresses colonic epithelial cell turnover and colon carcinogenesis through inhibition of the beta-catenin/T cell factor (TCF) pathway. Journal of Pharmacological Sciences. 106: 627-38. PMID 18391483 DOI: 10.1254/Jphs.Fp0071766  0.377
2008 Masuda A, Yoshida M, Shiomi H, Ikezawa S, Takagawa T, Tanaka H, Chinzei R, Ishida T, Morita Y, Kutsumi H, Inokuchi H, Wang S, Kobayashi K, Mizuno S, Nakamura A, ... ... Blumberg RS, et al. Fcgamma receptor regulation of Citrobacter rodentium infection. Infection and Immunity. 76: 1728-37. PMID 18227164 DOI: 10.1128/Iai.01493-07  0.428
2008 Sugimoto K, Ogawa A, Mizoguchi E, Shimomura Y, Andoh A, Bhan AK, Blumberg RS, Xavier RJ, Mizoguchi A. IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis. The Journal of Clinical Investigation. 118: 534-44. PMID 18172556 DOI: 10.1172/Jci33194  0.327
2008 Dickinson BL, Claypool SM, D'Angelo JA, Aiken ML, Venu N, Yen EH, Wagner JS, Borawski JA, Pierce AT, Hershberg R, Blumberg RS, Lencer WI. Ca2+-dependent calmodulin binding to FcRn affects immunoglobulin G transport in the transcytotic pathway. Molecular Biology of the Cell. 19: 414-23. PMID 18003977 DOI: 10.1091/Mbc.E07-07-0658  0.63
2008 Zeissig S, Kaser A, Dougan S, Blumberg R. Das Microsomale Triglyzerid-Transferprotein (MTP) beeinflusst die CD1d-vermittelte Antigen-Präsentation von Hepatozyten und reguliert die periphere Natural Killer T (NKT)-Zell Homöostase Zeitschrift FüR Gastroenterologie. 46. DOI: 10.1055/S-0028-1089464  0.613
2008 Masuda A, Yoshida M, Ishida T, Chinzei R, Tanaka H, Shiomi H, Mizuno S, Blumberg RS, Azuma T. W1210 FC Gamma Receptors On Antigen Presenting Cells Can Regulate the Mucosal Defense Against Enteric Bacteria Gastroenterology. 134: A-655. DOI: 10.1016/S0016-5085(08)63059-0  0.409
2008 Zeissig S, Kaser A, Dougan SK, Blumberg RS. T1241 Microsomal Triglyceride Transfer Protein Regulates CD1d-Restricted Antigen Presentation of Hepatocytes and Controls Natural Killer T Cell Homeostasis Via CD1d-Mediated Apoptosis Gastroenterology. 134: A-514. DOI: 10.1016/S0016-5085(08)62398-7  0.649
2008 Qiao S, Kobayashi K, Johansen F, Sollid LM, Andersen JT, Milford EL, Roopenian DC, Lencer WI, Blumberg RS. T1225 Dependence of Antibody-Mediated Presentation of Antigen On FcRn Gastroenterology. 134: A-510. DOI: 10.1016/S0016-5085(08)62382-3  0.355
2008 Kuo T, de Muinck EJ, Claypool SM, Yoshida M, Nagaishi T, Lencer WI, Blumberg RS. 1047 N-Glycan Moieties in FcRn Determines Steady-State Membrane Distribution and Directional Trafficking But Not Cross-Species IgG Binding Gastroenterology. 134: A-156. DOI: 10.1016/S0016-5085(08)60726-X  0.591
2008 Kobayashi K, Qiao S, Kuo T, de Muinck EJ, Imai K, Shinomura Y, Yoshida M, Lencer WI, Blumberg RS. 1046 Anti-Flagellin Specific IgG Is Pathogenic in Colitis Through FcRn-Regulated Antigen Presentation Pathways Gastroenterology. 134: A-156. DOI: 10.1016/S0016-5085(08)60725-8  0.35
2008 Nagahama K, Sugimoto K, Shimomura Y, Ogawa A, Andoh A, Kobayashi T, Kamada N, Hisamatsu T, Hibi T, Blumberg RS, Mizoguchi A. 518 Regulation of Colonic CD4+ T Cell Activation By Modification of Carbohydrate Assembly Gastroenterology. 134: A-73. DOI: 10.1016/S0016-5085(08)60342-X  0.389
2008 Chen Z, Chen L, Qiao S, Nagaishi T, Blumberg R. Su.97. Inhibitory Regulation of CEACAM1 on T Cell Receptor and NKG2D Mediated Signaling Clinical Immunology. 127: S155-S156. DOI: 10.1016/J.Clim.2008.03.448  0.37
2007 Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, Vignali KM, Cross R, Sehy D, Blumberg RS, Vignali DA. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature. 450: 566-9. PMID 18033300 DOI: 10.1038/Nature06306  0.397
2007 Stern-Ginossar N, Nedvetzki S, Markel G, Gazit R, Betser-Cohen G, Achdout H, Aker M, Blumberg RS, Davis DM, Appelmelk B, Mandelboim O. Intercellular transfer of carcinoembryonic antigen from tumor cells to NK cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 4424-34. PMID 17878338 DOI: 10.4049/Jimmunol.179.7.4424  0.398
2007 Zeissig S, Kaser A, Dougan SK, Nieuwenhuis EE, Blumberg RS. Role of NKT cells in the digestive system. III. Role of NKT cells in intestinal immunity. American Journal of Physiology. Gastrointestinal and Liver Physiology. 293: G1101-5. PMID 17717040 DOI: 10.1152/Ajpgi.00342.2007  0.697
2007 Kugathasan S, Saubermann LJ, Smith L, Kou D, Itoh J, Binion DG, Levine AD, Blumberg RS, Fiocchi C. Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease. Gut. 56: 1696-705. PMID 17682002 DOI: 10.1136/Gut.2006.116467  0.362
2007 Dougan SK, Kaser A, Blumberg RS. CD1 expression on antigen-presenting cells. Current Topics in Microbiology and Immunology. 314: 113-41. PMID 17593659 DOI: 10.1007/978-3-540-69511-0_5  0.626
2007 Hausding M, Karwot R, Scholtes P, Lehr HA, Wegmann M, Renz H, Galle PR, Birkenbach M, Neurath MF, Blumberg RS, Finotto S. Lung CD11c+ cells from mice deficient in Epstein-Barr virus-induced gene 3 (EBI-3) prevent airway hyper-responsiveness in experimental asthma. European Journal of Immunology. 37: 1663-77. PMID 17506035 DOI: 10.1002/Eji.200636675  0.334
2007 van Dieren JM, van der Woude CJ, Kuipers EJ, Escher JC, Samsom JN, Blumberg RS, Nieuwenhuis EE. Roles of CD1d-restricted NKT cells in the intestine. Inflammatory Bowel Diseases. 13: 1146-52. PMID 17476670 DOI: 10.1002/Ibd.20164  0.475
2007 Mizoguchi A, Ogawa A, Takedatsu H, Sugimoto K, Shimomura Y, Shirane K, Nagahama K, Nagaishi T, Mizoguchi E, Blumberg RS, Bhan AK. Dependence of intestinal granuloma formation on unique myeloid DC-like cells. The Journal of Clinical Investigation. 117: 605-15. PMID 17318261 DOI: 10.1172/Jci30150  0.377
2007 Dougan SK, Rava P, Hussain MM, Blumberg RS. MTP regulated by an alternate promoter is essential for NKT cell development. The Journal of Experimental Medicine. 204: 533-45. PMID 17312007 DOI: 10.1084/Jem.20062006  0.663
2007 Sartor RB, Blumberg RS, Braun J, Elson CO, Mayer LF. CCFA microbial-host interactions workshop: highlights and key observations. Inflammatory Bowel Diseases. 13: 600-19. PMID 17294437 DOI: 10.1002/Ibd.20114  0.377
2007 Probert CS, Saubermann LJ, Balk S, Blumberg RS. Repertoire of the alpha beta T-cell receptor in the intestine. Immunological Reviews. 215: 215-25. PMID 17291291 DOI: 10.1111/J.1600-065X.2006.00480.X  0.468
2007 Perera L, Shao L, Patel A, Evans K, Meresse B, Blumberg R, Geraghty D, Groh V, Spies T, Jabri B, Mayer L. Expression of nonclassical class I molecules by intestinal epithelial cells. Inflammatory Bowel Diseases. 13: 298-307. PMID 17238179 DOI: 10.1002/Ibd.20026  0.44
2007 Kawana K, Quayle AJ, Ficarra M, Ibana JA, Shen L, Kawana Y, Yang H, Marrero L, Yavagal S, Greene SJ, Zhang YX, Pyles RB, Blumberg RS, Schust DJ. CD1d degradation in Chlamydia trachomatis-infected epithelial cells is the result of both cellular and chlamydial proteasomal activity. The Journal of Biological Chemistry. 282: 7368-75. PMID 17215251 DOI: 10.1074/Jbc.M610754200  0.388
2007 Qiao SW, Lencer WI, Blumberg RS. How the controller is controlled - Neonatal Fc receptor expression and immunoglobulin G homeostasis Immunology. 120: 145-147. PMID 17140402 DOI: 10.1111/J.1365-2567.2006.02507.X  0.357
2007 Lu SX, Willis L, Smith M, Suh D, King C, Bautista J, Chow M, Cabrera-Perez J, Hubbard V, Rotolo J, Liu C, Murphy G, Alpdogan O, Blumberg R, Holmes K, et al. CEACAM-1 Is Involved in Graft-Versus-Host-Disease in Murine Allogeneic Bone Marrow Transplantation Models. Blood. 110: 67-67. DOI: 10.1182/Blood.V110.11.67.67  0.374
2007 Dokmeci E, Xu L, Blumberg R, Bottomly K. EBI3 Deficient Naive T cells Show Increase in Expression of Th2 Mediated Cytokines In-vitro Journal of Allergy and Clinical Immunology. 119: S45. DOI: 10.1016/J.Jaci.2006.11.197  0.391
2006 Bulwin GC, Heinemann T, Bugge V, Winter M, Lohan A, Schlawinsky M, Schulze A, Wälter S, Sabat R, Schülein R, Wiesner B, Veh RW, Löhler J, Blumberg RS, Volk HD, et al. TIRC7 inhibits T cell proliferation by modulation of CTLA-4 expression Journal of Immunology. 177: 6833-6841. PMID 17082597 DOI: 10.4049/Jimmunol.177.10.6833  0.441
2006 Nagaishi T, Pao L, Lin SH, Iijima H, Kaser A, Qiao SW, Chen Z, Glickman J, Najjar SM, Nakajima A, Neel BG, Blumberg RS. SHP1 Phosphatase-Dependent T Cell Inhibition by CEACAM1 Adhesion Molecule Isoforms Immunity. 25: 769-781. PMID 17081782 DOI: 10.1016/J.Immuni.2006.08.026  0.423
2006 Nagaishi T, Iijima H, Nakajima A, Chen D, Blumberg RS. Role of CEACAM1 as a regulator of T cells Annals of the New York Academy of Sciences. 1072: 155-175. PMID 17057197 DOI: 10.1196/Annals.1326.004  0.454
2006 Markel G, Seidman R, Stern N, Cohen-Sinai T, Izhaki O, Katz G, Besser M, Treves AJ, Blumberg RS, Loewenthal R, Mandelboim O, Orenstein A, Schachter J. Inhibition of human tumor-infiltrating lymphocyte effector functions by the homophilic carcinoembryonic cell adhesion molecule 1 interactions. Journal of Immunology (Baltimore, Md. : 1950). 177: 6062-71. PMID 17056532 DOI: 10.4049/Jimmunol.177.9.6062  0.405
2006 Yoshida M, Masuda A, Kuo TT, Kobayashi K, Claypool SM, Takagawa T, Kutsumi H, Azuma T, Lencer WI, Blumberg RS. IgG transport across mucosal barriers by neonatal Fc receptor for IgG and mucosal immunity. Springer Seminars in Immunopathology. 28: 397-403. PMID 17051393 DOI: 10.1007/S00281-006-0054-Z  0.706
2006 Wirtz S, Tubbe I, Galle PR, Schild HJ, Birkenbach M, Blumberg RS, Neurath MF. Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27 Journal of Experimental Medicine. 203: 1875-1881. PMID 16880260 DOI: 10.1084/Jem.20060471  0.302
2006 Yoshida M, Kobayashi K, Kuo TT, Bry L, Glickman JN, Claypool SM, Kaser A, Nagaishi T, Higgins DE, Mizoguchi E, Wakatsuki Y, Roopenian DC, Mizoguchi A, Lencer WI, Blumberg RS. Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria. The Journal of Clinical Investigation. 116: 2142-2151. PMID 16841095 DOI: 10.1172/Jci27821  0.675
2006 Gray-Owen SD, Blumberg RS. CEACAM1: Contact-dependent control of immunity Nature Reviews Immunology. 6: 433-446. PMID 16724098 DOI: 10.1038/Nri1864  0.397
2006 Nieuwenhuis EES, Blumberg RS. The role of the epithelial barrier in inflammatory bowel disease Advances in Experimental Medicine and Biology. 579: 108-116. PMID 16620014 DOI: 10.1007/0-387-33778-4_7  0.421
2006 Utku N, Heinemann T, Winter M, Bulwin CG, Schlawinsky M, Fraser P, Nieuwenhuis EES, Volk HD, Blumberg RS. Antibody targeting of TIRC7 results in significant therapeutic effects on collagen-induced arthritis in mice Clinical and Experimental Immunology. 144: 142-151. PMID 16542376 DOI: 10.1111/J.1365-2249.2006.03044.X  0.38
2006 Wada K, Nakajima A, Katayama K, Kudo C, Shibuya A, Kubota N, Terauchi Y, Tachibana M, Miyoshi H, Kamisaki Y, Mayumi T, Kadowaki T, Blumberg RS. Peroxisome proliferator-activated receptor gamma-mediated regulation of neural stem cell proliferation and differentiation. The Journal of Biological Chemistry. 281: 12673-81. PMID 16524877 DOI: 10.1074/Jbc.M513786200  0.322
2006 Brozovic S, Sahoo R, Barve S, Shiba H, Uriarte S, Blumberg RS, Kinane DF. Porphyromonas gingivalis enhance FasL expression via up-regulations if NFκB-mediated gene transcription and induces apoptopic cell death in human gingival epithelial cells Microbiology. 152: 797-806. PMID 16514159 DOI: 10.1099/Mic.0.28472-0  0.351
2006 Johansen FE, Yen EH, Dickinson B, Yoshida M, Claypool S, Blumberg RS, Lencer WI. Biology of Gut Immunoglobulins Physiology of the Gastrointestinal Tract. 2: 1067-1090. DOI: 10.1016/B978-012088394-3/50046-5  0.61
2006 Hershberg R, Blumberg RS. The lymphocyte-epithelial-bacterial interface Inflammatory Bowel Disease: From Bench to Bedside. 121-146. DOI: 10.1007/0-387-25808-6_6  0.33
2005 Leav BA, Yoshida M, Rogers K, Cohen S, Godiwala N, Blumberg RS, Ward H. An early intestinal mucosal source of gamma interferon is associated with resistance to and control of Cryptospondium parvum infection in mice Infection and Immunity. 73: 8425-8428. PMID 16299343 DOI: 10.1128/Iai.73.12.8425-8428.2005  0.369
2005 Furuta GT, Nieuwenhuis EES, Karhausen J, Gleich G, Blumberg RS, Lee JJ, Ackerman SJ. Eosinophils alter colonic epithelial barrier function: Role for major basic protein American Journal of Physiology - Gastrointestinal and Liver Physiology. 289: G890-G897. PMID 16227527 DOI: 10.1152/Ajpgi.00015.2005  0.416
2005 Dougan SK, Salas A, Rava P, Agyemang A, Kaser A, Morrison J, Khurana A, Kronenberg M, Johnson C, Exley M, Hussain MM, Blumberg RS. Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells. The Journal of Experimental Medicine. 202: 529-39. PMID 16087713 DOI: 10.1084/Jem.20050183  0.647
2005 Tokuyama H, Ueha S, Kurachi M, Matsushima K, Moriyasu F, Blumberg RS, Kakimi K. The simultaneous blockade of chemokine receptors CCR2, CCR5 and CXCR3 by a non-peptide chemokine receptor antagonist protects mice from dextran sodium sulfate-mediated colitis. International Immunology. 17: 1023-34. PMID 16000328 DOI: 10.1093/Intimm/Dxh284  0.383
2005 Nieuwenhuis EE, Gillessen S, Scheper RJ, Exley MA, Taniguchi M, Balk SP, Strominger JL, Dranoff G, Blumberg RS, Wilson SB. CD1d and CD1d-restricted iNKT-cells play a pivotal role in contact hypersensitivity. Experimental Dermatology. 14: 250-8. PMID 15810882 DOI: 10.1111/J.0906-6705.2005.00289.X  0.406
2005 Stirling CMA, Charleston B, Takamatsu H, Claypool S, Lencer W, Blumberg RS, Wileman TE. Characterization of the porcine neonatal Fc receptor - Potential use for trans-epithelial protein delivery Immunology. 114: 542-553. PMID 15804291 DOI: 10.1111/J.1365-2567.2004.02121.X  0.671
2005 Wirtz S, Becker C, Fantini MC, Nieuwenhuis EE, Tubbe I, Galle PR, Schild HJ, Birkenbach M, Blumberg RS, Neurath MF. EBV-induced gene 3 transcription is induced by TLR signaling in primary dendritic cells via NF-κB activation Journal of Immunology. 174: 2814-2824. PMID 15728491 DOI: 10.4049/Jimmunol.174.5.2814  0.337
2005 Lencer WI, Blumberg RS. A passionate kiss, then run: Exocytosis and recycling of IgG by FcRn Trends in Cell Biology. 15: 5-9. PMID 15653072 DOI: 10.1016/J.Tcb.2004.11.004  0.333
2004 Kaser A, Nieuwenhuis EE, Strober W, Mayer L, Fuss I, Colgan S, Blumberg RS. Natural killer T cells in mucosal homeostasis. Annals of the New York Academy of Sciences. 1029: 154-68. PMID 15681754 DOI: 10.1196/Annals.1309.032  0.448
2004 Yoneda M, Wada K, Katayama K, Nakajima N, Iwasaki T, Osawa E, Mukasa K, Yamada Y, Blumberg RS, Sekihara H, Nakajima A. A novel therapy for acute hepatitis utilizing dehydroepiandrosterone in the murine model of hepatitis Biochemical Pharmacology. 68: 2283-2289. PMID 15498518 DOI: 10.1016/J.Bcp.2004.07.044  0.325
2004 Anfossi N, Robbins SH, Ugolini S, Georgel P, Hoebe K, Bouneaud C, Ronet C, Kaser A, DiCioccio CB, Tomasello E, Blumberg RS, Beutler B, Reiner SL, Alexopoulou L, Lantz O, et al. Expansion and function of CD8+ T cells expressing Ly49 inhibitory receptors specific for MHC class I molecules. Journal of Immunology (Baltimore, Md. : 1950). 173: 3773-82. PMID 15356124 DOI: 10.4049/Jimmunol.173.6.3773  0.406
2004 Markel G, Gruda R, Achdout H, Katz G, Nechama M, Blumberg RS, Kammerer R, Zimmermann W, Mandelboim O. The critical role of residues 43R and 44Q of carcinoembryonic antigen cell adhesion molecules-1 in the protection from killing by human NK cells Journal of Immunology. 173: 3732-3739. PMID 15356119 DOI: 10.4049/Jimmunol.173.6.3732  0.324
2004 Utku N, Boerner A, Tomschegg A, Bennai-Sanfourche F, Bulwin GC, Heinemann T, Loehler J, Blumberg RS, Volk HD. TIRC7 deficiency causes in vitro and in vivo augmentation of T and B cell activation and cytokine response Journal of Immunology. 173: 2342-2352. PMID 15294947 DOI: 10.4049/Jimmunol.173.4.2342  0.42
2004 Markel G, Achdout H, Katz G, Ling KL, Salio M, Gruda R, Gazit R, Mizrahi S, Hanna J, Gonen-Gross T, Arnon TI, Lieberman N, Stren N, Nachmias B, Blumberg RS, et al. Biological function of the soluble CEACAM1 protein and implications in TAP2-deficient patients European Journal of Immunology. 34: 2138-2148. PMID 15259011 DOI: 10.1002/Eji.200425021  0.332
2004 Bitonti AJ, Dumont JA, Low SC, Peters RT, Kropp KE, Palombella VJ, Stattel JM, Lu Y, Tan CA, Song JJ, Garcia AM, Simister NE, Spiekermann GM, Lencer WI, Blumberg RS. Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway. Proceedings of the National Academy of Sciences of the United States of America. 101: 9763-8. PMID 15210944 DOI: 10.1073/Pnas.0403235101  0.323
2004 Yoshida M, Claypool SM, Wagner JS, Mizoguchi E, Mizoguchi A, Roopenian DC, Lencer WI, Blumberg RS. Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells. Immunity. 20: 769-83. PMID 15189741 DOI: 10.1016/J.Immuni.2004.05.007  0.708
2004 Hokama A, Mizoguchi E, Sugimoto K, Shimomura Y, Tanaka Y, Yoshida M, Rietdijk ST, de Jong YP, Snapper SB, Terhorst C, Blumberg RS, Mizoguchi A. Induced reactivity of intestinal CD4(+) T cells with an epithelial cell lectin, galectin-4, contributes to exacerbation of intestinal inflammation. Immunity. 20: 681-93. PMID 15189734 DOI: 10.1016/J.Immuni.2004.05.009  0.463
2004 Kaser A, Blumberg RS. The other way round: Colitis regulates regulatory T cells Gastroenterology. 126: 1903-1906. PMID 15188188 DOI: 10.1053/J.Gastro.2004.04.027  0.383
2004 Kaser A, Nieuwenhuis EES, Strober W, Fuss I, Colgan S, Blumberg RS. CD1d-restricted T cell pathways at the epithelial-lymphocyte-luminal interface Journal of Pediatric Gastroenterology and Nutrition. 39: S719-722. PMID 15167359 DOI: 10.1097/00005176-200406003-00002  0.416
2004 Fuss IJ, Heller F, Boirivant M, Leon F, Yoshida M, Fichtner-Feigl S, Yang Z, Exley M, Kitani A, Blumberg RS, Mannon P, Strober W. Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis. The Journal of Clinical Investigation. 113: 1490-7. PMID 15146247 DOI: 10.1172/Jci19836  0.389
2004 Brozovic S, Nagaishi T, Yoshida M, Betz S, Salas A, Chen D, Kaser A, Glickman J, Kuo T, Little A, Morrison J, Corazza N, Kim JY, Colgan SP, Young SG, ... ... Blumberg RS, et al. CD1d function is regulated by microsomal triglyceride transfer protein Nature Medicine. 10: 535-539. PMID 15107843 DOI: 10.1038/Nm1043  0.436
2004 Kumamoto Y, Tomschegg A, Bennai-Sanfourche F, Boerner A, Kaser A, Schmidt-Knosalla I, Heinemann T, Schlawinsky M, Blumberg RS, Volk HD, Utku N. Monoclonal Antibody Specific for TIRC7 Induces Donor-specific Anergy and Prevents Rejection of Cardiac Allografts in Mice American Journal of Transplantation. 4: 505-514. PMID 15023142 DOI: 10.1111/J.1600-6143.2004.00367.X  0.392
2004 Chen D, Iijima H, Nagaishi T, Nakajima A, Russell S, Raychowdhury R, Morales V, Rudd CE, Utku N, Blumberg RS. Carcinoembryonic antigen-related cellular adhesion molecule 1 isoforms alternatively inhibit and costimulate human T cell function. Journal of Immunology (Baltimore, Md. : 1950). 172: 3535-43. PMID 15004154 DOI: 10.4049/Jimmunol.172.6.3535  0.403
2004 Iijima H, Neurath MF, Nagaishi T, Glickman JN, Nieuwenhuis EE, Nakajima A, Chen D, Fuss IJ, Utku N, Lewicki DN, Becker C, Gallagher TM, Holmes KV, Blumberg RS. Specific regulation of T helper cell 1-mediated murine colitis by CEACAM1. The Journal of Experimental Medicine. 199: 471-82. PMID 14970176 DOI: 10.1084/Jem.20030437  0.438
2004 Claypool SM, Dickinson BL, Wagner JS, Johansen FE, Venu N, Borawski JA, Lencer WI, Blumberg RS. Bidirectional transepithelial IgG transport by a strongly polarized basolateral membrane Fcgamma-receptor. Molecular Biology of the Cell. 15: 1746-59. PMID 14767057 DOI: 10.1091/Mbc.E03-11-0832  0.648
2004 Markel G, Mussaffi H, Ling KL, Salio M, Gadola S, Steuer G, Blau H, Achdout H, de Miguel M, Gonen-Gross T, Hanna J, Arnon TI, Qimron U, Volovitz I, Eisenbach L, ... Blumberg RS, et al. The mechanisms controlling NK cell autoreactivity in TAP2-deficient patients. Blood. 103: 1770-8. PMID 14604968 DOI: 10.1182/Blood-2003-06-2114  0.382
2003 Colgan SP, Pitman RS, Nagaishi T, Mizoguchi A, Mizoguchi E, Mayer LF, Shao L, Sartor RB, Subjeck JR, Blumberg RS. Intestinal heat shock protein 110 regulates expression of CD1d on intestinal epithelial cells. The Journal of Clinical Investigation. 112: 745-54. PMID 12952923 DOI: 10.1172/Jci17241  0.415
2003 Gillessen S, Naumov YN, Nieuwenhuis EE, Exley MA, Lee FS, Mach N, Luster AD, Blumberg RS, Taniguchi M, Balk SP, Strominger JL, Dranoff G, Wilson SB. CD1d-restricted T cells regulate dendritic cell function and antitumor immunity in a granulocyte-macrophage colony-stimulating factor-dependent fashion. Proceedings of the National Academy of Sciences of the United States of America. 100: 8874-9. PMID 12847287 DOI: 10.1073/Pnas.1033098100  0.421
2003 van de Wal Y, Corazza N, Allez M, Mayer LF, Iijima H, Ryan M, Cornwall S, Kaiserlian D, Hershberg R, Koezuka Y, Colgan SP, Blumberg RS. Delineation of a CD1d-restricted antigen presentation pathway associated with human and mouse intestinal epithelial cells. Gastroenterology. 124: 1420-31. PMID 12730881 DOI: 10.1016/S0016-5085(03)00219-1  0.458
2003 Katayama K, Wada K, Nakajima A, Mizuguchi H, Hayakawa T, Nakagawa S, Kadowaki T, Nagai R, Kamisaki Y, Blumberg RS, Mayumi T. A novel PPARγ gene therapy to control inflammation associated with inflammatory bowel disease in a murine model Gastroenterology. 124: 1315-1324. PMID 12730872 DOI: 10.1016/S0016-5085(03)00262-2  0.343
2003 Tiede I, Fritz G, Strand S, Poppe D, Dvorsky R, Strand D, Lehr HA, Wirtz S, Becker C, Atreya R, Mudter J, Hildner K, Bartsch B, Holtmann M, Blumberg R, et al. CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes. The Journal of Clinical Investigation. 111: 1133-45. PMID 12697733 DOI: 10.1172/Jci16432  0.36
2003 Shah U, Dickinson BL, Blumberg RS, Simister NE, Lencer WI, Walker WA. Distribution of the IgG Fc receptor, FcRn, in the human fetal intestine. Pediatric Research. 53: 295-301. PMID 12538789 DOI: 10.1203/01.Pdr.0000047663.81816.E3  0.361
2003 Wirtz SJ, Becker C, Nieuwenhuis EE, Birkenbach M, Blumberg RS, Neurath MF. in vivo and in vitro analysis of the functional role of Epstein-Barr virus-induced gene 3 (EBI3) for regulation of Th2 mediated immune responses Gastroenterology. 124: A335. DOI: 10.1016/S0016-5085(03)81688-8  0.325
2003 Tiede I, Poppe D, Strand S, Strand D, Wirtz S, Becker C, Blumberg R, Iven H, Ahmadian RM, Galle PR, Neurath MF. A novel molecular mechanism of action for azathioprine in IBD: 6-Thio-GTP induces apoptosis of lamina propria T cells via blockade of the GTPase Rac1 Gastroenterology. 124: A321. DOI: 10.1016/S0016-5085(03)81616-5  0.377
2003 Colgan SP, Nagaishi T, Mizoguchi A, Mizoguchi E, Mayer L, Sartor RB, Subjeck JR, Blumberg RS. Intestinal lumen-derived heat shock protein 110 regulates expression of the MHC-class I-like molecule CD1d on intestinal epithelial cells Gastroenterology. 124: A82-A83. DOI: 10.1016/S0016-5085(03)80407-9  0.354
2003 Yoshida M, Claypool SM, Mizoguchi A, Mizoguchi E, Roopenian DC, Lencer WI, Blumberg RS. FCRN regulates transport of IgG and IgG/antigen complexes across mucosal epithelial barriers Gastroenterology. 124: A60. DOI: 10.1016/S0016-5085(03)80297-4  0.647
2003 Heller F, Boirivant M, Mannon P, Blumberg RS, Nieuwenhaus E, Strober W, Fuss IJ. IL-13 secretion by CD4+CD161+ NK-T cells is increased in oxazolone and human ulcerative colitis (UC) Gastroenterology. 124: A35-A36. DOI: 10.1016/S0016-5085(03)80175-0  0.342
2003 Iijima H, Nagaishi T, Neurath M, Glickman J, Nakajima A, Gallagher T, Holmes K, Blumberg RS. Specific regulation of T helper-1 mediated murine colitis by CEACMI Gastroenterology. 124: A26. DOI: 10.1016/S0016-5085(03)80126-9  0.367
2002 Nieuwenhuis EES, Neurath MF, Corazza N, Iijima H, Trgovcich J, Wirtz S, Glickman J, Bailey D, Yoshida M, Galle PR, Kronenberg M, Birkenbach M, Blumberg RS. Disruption of T helper 2-immune responses in Epstein-Barr virus-induced gene 3-deficient mice Proceedings of the National Academy of Sciences of the United States of America. 99: 16951-16956. PMID 12482940 DOI: 10.1073/Pnas.252648899  0.378
2002 Saubermann LJ, Nakajima A, Wada K, Zhao S, Terauchi Y, Kadowaki T, Aburatani H, Matsuhashi N, Nagai R, Blumberg RS. Peroxisome proliferator-activated receptor gamma agonist ligands stimulate a Th2 cytokine response and prevent acute colitis. Inflammatory Bowel Diseases. 8: 330-9. PMID 12479648 DOI: 10.1097/00054725-200209000-00004  0.335
2002 Heller F, Fuss IJ, Nieuwenhuis EE, Blumberg RS, Strober W. Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells Immunity. 17: 629-638. PMID 12433369 DOI: 10.1016/S1074-7613(02)00453-3  0.394
2002 Perez A, Grikscheit TC, Blumberg RS, Ashley SW, Vacanti JP, Whang EE. Tissue-engineered small intestine: Ontogeny of the immune system Transplantation. 74: 619-623. PMID 12352876 DOI: 10.1097/00007890-200209150-00006  0.374
2002 Spiekermann GM, Finn PW, Sally Ward E, Dumont J, Dickinson BL, Blumberg RS, Lencer WI. Receptor-mediated immunoglobulin G transport across mucosal barriers in adult life: Functional expression of FcRn in the mammalian lung Journal of Experimental Medicine. 196: 303-310. PMID 12163559 DOI: 10.1084/Jem.20020400  0.402
2002 Nieuwenhuis EE, Matsumoto T, Exley M, Schleipman RA, Glickman J, Bailey DT, Corazza N, Colgan SP, Onderdonk AB, Blumberg RS. CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung. Nature Medicine. 8: 588-93. PMID 12042809 DOI: 10.1038/Nm0602-588  0.373
2002 Claypool SM, Dickinson BL, Yoshida M, Lencer WI, Blumberg RS. Functional reconstitution of human FcRn in Madin-Darby canine kidney cells requires co-expressed human beta 2-microglobulin. The Journal of Biological Chemistry. 277: 28038-50. PMID 12023961 DOI: 10.1074/Jbc.M202367200  0.648
2002 Neurath MF, Weigmann B, Finotto S, Glickman J, Nieuwenhuis E, Iijima H, Mizoguchi A, Mizoguchi E, Mudter J, Galle PR, Bhan A, Autschbach F, Sullivan BM, Szabo SJ, Glimcher LH, ... Blumberg RS, et al. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease Journal of Experimental Medicine. 195: 1129-1143. PMID 11994418 DOI: 10.1084/Jem.20011956  0.404
2002 Markel G, Lieberman N, Katz G, Arnon TI, Lotem M, Drize O, Blumberg RS, Bar-Haim E, Mader R, Eisenbach L, Mandelboim O. CD66a interactions between human melanoma and NK cells: a novel class I MHC-independent inhibitory mechanism of cytotoxicity. Journal of Immunology (Baltimore, Md. : 1950). 168: 2803-10. PMID 11884449 DOI: 10.4049/Jimmunol.168.6.2803  0.38
2002 Mizoguchi A, Mizoguchi E, Takedatsu H, Blumberg RS, Bhan AK. Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation Immunity. 16: 219-230. PMID 11869683 DOI: 10.1016/S1074-7613(02)00274-1  0.396
2002 Strober W, Fuss IJ, Blumberg RS. The immunology of mucosal models of inflammation Annual Review of Immunology. 20: 495-549. PMID 11861611 DOI: 10.1146/Annurev.Immunol.20.100301.064816  0.371
2002 Nakajima A, Iijima H, Neurath MF, Nagaishi T, Nieuwenhuis EE, Raychowdhury R, Glickman J, Blau DM, Russell S, Holmes KV, Blumberg RS. Activation-induced expression of carcinoembryonic antigen-cell adhesion molecule 1 regulates mouse T lymphocyte function. Journal of Immunology (Baltimore, Md. : 1950). 168: 1028-35. PMID 11801635 DOI: 10.4049/Jimmunol.168.3.1028  0.454
2002 Wirtz S, Becker C, Blumberg R, Galle PR, Neurath MF. Treatment of T cell-dependent experimental colitis in SCID mice by local administration of an adenovirus expressing IL-18 antisense mRNA. Journal of Immunology (Baltimore, Md. : 1950). 168: 411-20. PMID 11751987 DOI: 10.4049/Jimmunol.168.1.411  0.38
2002 Omata F, Birkenbach M, Matsuzaki S, Christ AD, Blumberg RS. The expression of IL-12 p40 and its homologue, Epstein-Barr virus-induced gene 3, in inflammatory bowel disease. Inflammatory Bowel Diseases. 7: 215-20. PMID 11515847 DOI: 10.1097/00054725-200108000-00006  0.316
2001 Wada K, Nakajima A, Blumberg RS. PPARgamma and inflammatory bowel disease: a new therapeutic target for ulcerative colitis and Crohn's disease. Trends in Molecular Medicine. 7: 329-31. PMID 11516972 DOI: 10.1016/S1471-4914(01)02076-7  0.352
2001 Blumberg RS, van de Wal Y, Claypool S, Corazza N, Dickinson B, Nieuwenhuis E, Pitman R, Spiekermann G, Zhu X, Colgan S, Lencer WI. The multiple roles of major histocompatibility complex class-I-like molecules in mucosal immune function. Acta Odontologica Scandinavica. 59: 139-44. PMID 11501882 DOI: 10.1080/000163501750266729  0.681
2001 Probert CS, Chott A, Saubermann LJ, Stevens AC, Balk SP, Blumberg RS. Prevalence of an ulcerative colitis-associated CD8+ T cell receptor beta-chain CDR3-region motif and its association with disease activity. Journal of Clinical Immunology. 21: 126-34. PMID 11332651 DOI: 10.1023/A:1011007922707  0.402
2001 Blumberg RS. Characterization of CD1d in mucosal immune function: an immunotherapeutic target for inflammatory bowel disease. The Keio Journal of Medicine. 50: 39-44. PMID 11296664 DOI: 10.2302/Kjm.50.39  0.452
2001 Zhu X, Meng G, Dickinson BL, Li X, Mizoguchi E, Miao L, Wang Y, Robert C, Wu B, Smith PD, Lencer WI, Blumberg RS. MHC class I-related neonatal Fc receptor for IgG is functionally expressed in monocytes, intestinal macrophages, and dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 166: 3266-76. PMID 11207281 DOI: 10.4049/Jimmunol.166.5.3266  0.439
2001 Blumberg RS, Strober W. Prospects for research in inflammatory bowel disease. Jama. 285: 643-647. PMID 11176874 DOI: 10.1001/Jama.285.5.643  0.344
2001 Nakajima A, Wada K, Miki H, Kubota N, Nakajima N, Terauchi Y, Ohnishi S, Saubermann LJ, Kadowaki T, Blumberg RS, Nagai R, Matsuhashi N. Endogenous PPAR gamma mediates anti-inflammatory activity in murine ischemia-reperfusion injury. Gastroenterology. 120: 460-9. PMID 11159886 DOI: 10.1053/Gast.2001.21191  0.316
2001 Dickinson BL, Claypool SM, Blumberg RS, Lencer WI. Functional interaction of calmodulin with the Fcγ-receptor FcRn Gastroenterology. 120: A698. DOI: 10.1016/S0016-5085(08)83475-0  0.601
2001 Christ AD, Saubermann LJ, Rousson V, Blumberg RS. Oligoclonality of gastric T lymphocytes as defined by objective messure of T receptor-beta chain CDR3 size Gastroenterology. 120: A322. DOI: 10.1016/S0016-5085(08)81600-9  0.443
2001 Pitman RS, Nieuwenhuis EE, Wal Yvd, Colgan SP, Blumberg RS. Intestinal epithelial cell (IEC) expression of the major histocompatibility complex (MHC) class I-like molecule, CD1d, is upregulated by lumenal components of the gastrointestinal tract Gastroenterology. 120: A187-A188. DOI: 10.1016/S0016-5085(08)80929-8  0.359
2001 Van de Wal Y, Pitman RS, Hershberg RM, Colgan SP, Behar S, Ryan M, Koezuka Y, Blumberg RS. Human and mouse intestinal epithelial cells (IEC) present glycolipid antigens to natural killer (NK)-T cells in a CD1d-restricted manner Gastroenterology. 120: A37. DOI: 10.1016/S0016-5085(08)80182-5  0.446
2000 Kim HS, Colgan SP, Pitman R, Hershberg RM, Blumberg RS. Human CD1d associates with prolyl-4-hydroxylase during its biosynthesis. Molecular Immunology. 37: 861-8. PMID 11257307 DOI: 10.1016/S0161-5890(00)00092-4  0.37
2000 Pitman RS, Blumberg RS. First line of defense: the role of the intestinal epithelium as an active component of the mucosal immune system. Journal of Gastroenterology. 35: 805-14. PMID 11085489 DOI: 10.1007/S005350070017  0.333
2000 Mizoguchi A, Mizoguchi E, Saubermann LJ, Higaki K, Blumberg RS, Bhan AK. Limited CD4 T-cell diversity associated with colitis in T-cell receptor α mutant mice requires a T helper 2 environment Gastroenterology. 119: 983-995. PMID 11040185 DOI: 10.1053/Gast.2000.18153  0.414
2000 Roberts AI, Blumberg RS, Christ AD, Brolin RE, Ebert EC. Staphylococcal enterotoxin B induces potent cytotoxic activity by intraepithelial lymphocytes. Immunology. 101: 185-90. PMID 11012771 DOI: 10.1046/J.1365-2567.2000.00088.X  0.404
2000 Wei Y, Mrsny RJ, Blumberg RS, Fried M, Christ AD. Choice of microcentrifuge tubes influences T cell proliferation assay. Biotechniques. 29: 54-6, 59. PMID 10907077 DOI: 10.2144/00291Bm10  0.354
2000 Saubermann LJ, Beck P, De Jong YP, Pitman RS, Ryan MS, Kim HS, Exley M, Snapper S, Balk SP, Hagen SJ, Kanauchi O, Motoki K, Sakai T, Terhorst C, Koezuka Y, ... ... Blumberg RS, et al. Activation of natural killer T cells by alpha-galactosylceramide in the presence of CD1d provides protection against colitis in mice. Gastroenterology. 119: 119-28. PMID 10889161 DOI: 10.1053/Gast.2000.9114  0.329
2000 Exley M, Garcia J, Wilson SB, Spada F, Gerdes D, Tahir SM, Patton KT, Blumberg RS, Porcelli S, Chott A, Balk SP. CD1d structure and regulation on human thymocytes, peripheral blood T cells, B cells and monocytes. Immunology. 100: 37-47. PMID 10809957 DOI: 10.1046/J.1365-2567.2000.00001.X  0.443
2000 Muehlhoefer A, Saubermann LJ, Gu X, Luedtke-Heckenkamp K, Xavier R, Blumberg RS, Podolsky DK, MacDermott RP, Reinecker HC. Fractalkine is an epithelial and endothelial cell-derived chemoattractant for intraepithelial lymphocytes in the small intestinal mucosa. Journal of Immunology (Baltimore, Md. : 1950). 164: 3368-76. PMID 10706732 DOI: 10.4049/Jimmunol.164.6.3368  0.442
2000 Blumberg RS, Saubermann LJ, Strober W. Corrigendum: Animal models of mucosal inflammation and their relation to human inflammatory bowel disease Current Opinion in Immunology. 12: 226. DOI: 10.1016/S0952-7915(99)00079-5  0.301
2000 Mizoguchi A, Mizoguchi E, Saubermann LJ, Higaki K, Blumberg RS, Bhan AK. Clonal expansionandsurvival of the colonic CD4+ VB8.2+ T cells characterized by a specific CDR3 motif in the TCRA KO mice with colitis Gastroenterology. 118: A687. DOI: 10.1016/S0016-5085(00)84880-5  0.373
2000 Spiekermann GM, Blumberg RS, Lencer WI. Transcytosis of Fc-fusion proteins across tbe epithelial cell barrier mediated by FcRn Gastroenterology. 118: A601. DOI: 10.1016/S0016-5085(00)84544-8  0.361
2000 Saubermann LJ, Beck P, de Jong YP, Pitman RS, Terhorst C, Exley M, Snapper SB, Balk SP, Hagen SJ, Podolsky Dk, Koezuka Y, Blumberg RS. Natural killer (NK)-T cell activation by a-galactosylceramide in the presence of cdid provides protection against colitis Gastroenterology. 118: A189. DOI: 10.1016/S0016-5085(00)82832-2  0.369
1999 Blumberg RS, Saubermann LJ, Strober W. Animal Models Of Mucosal Inflammation And Their Relation To Human Inflammatory Bowel Disease Current Opinion in Immunology. 11: 648-656. PMID 10631550 DOI: 10.1016/S0952-7915(99)00032-1  0.369
1999 Colgan SP, Hershberg RM, Furuta GT, Blumberg RS. Ligation of intestinal epithelial CD1d induces bioactive IL-10: Critical role of the cytoplasmic tail in autocrine signaling Proceedings of the National Academy of Sciences of the United States of America. 96: 13938-13943. PMID 10570177 DOI: 10.1073/Pnas.96.24.13938  0.381
1999 Dickinson BL, Badizadegan K, Wu Z, Ahouse JC, Zhu X, Simister NE, Blumberg RS, Lencer WI. Bidirectional FcRn-dependent IgG transport in a polarized human intestinal epithelial cell line Journal of Clinical Investigation. 104: 903-911. PMID 10510331 DOI: 10.1172/Jci6968  0.429
1999 Campbell NA, Kim HS, Blumberg RS, Mayer L. The nonclassical class I molecule CD1d associates with the novel CD8 ligand gp180 on intestinal epithelial cells. The Journal of Biological Chemistry. 274: 26259-65. PMID 10473580 DOI: 10.1074/Jbc.274.37.26259  0.388
1999 Blumberg RS, Lencer WI, Zhu X, Kim HS, Claypool S, Balk SP, Saubermann LJ, Colgan SP. Antigen presentation by intestinal epithelial cells Immunology Letters. 69: 7-11. PMID 10436875 DOI: 10.1016/S0165-2478(99)00093-0  0.688
1999 Somnay-Wadgaonkar K, Nusrat A, Kim HS, Canchis WP, Balk SP, Colgan SP, Blumberg RS. Immunolocalization of CD1d in human intestinal epithelial cells and identification of a beta2-microglobulin-associated form. International Immunology. 11: 383-92. PMID 10221650 DOI: 10.1093/Intimm/11.3.383  0.392
1999 Saubermann LJ, Probert CS, Christ AD, Chott A, Turner JR, Stevens AC, Balk SP, Blumberg RS. Evidence of T cell receptor beta-chain patterns in inflammatory and noninflammatory bowel disease states. The American Journal of Physiology. 276: G613-21. PMID 10070037 DOI: 10.1152/Ajpgi.1999.276.3.G613  0.437
1998 Utku N, Heinemann T, Tullius SG, Bulwin GC, Beinke S, Blumberg RS, Beato F, Randall J, Kojima R, Busconi L, Robertson ES, Schülein R, Volk HD, Milford EL, Gullans SR. Prevention of acute allograft rejection by antibody targeting of TIRC7, a novel T cell membrane protein Immunity. 9: 509-518. PMID 9806637 DOI: 10.1016/S1074-7613(00)80634-2  0.399
1998 Probert CS, Aitken EW, Saubermann LJ, Balk SP, Blumberg RS. T-cell receptor usage in the intestine. Chemical Immunology. 71: 27-39. PMID 9761945 DOI: 10.1159/000058717  0.397
1998 Christ AD, Stevens AC, Koeppen H, Walsh S, Omata F, Devergne O, Birkenbach M, Blumberg RS. An interleukin 12-related cytokine is up-regulated in ulcerative colitis but not in Crohn's disease. Gastroenterology. 115: 307-13. PMID 9679036 DOI: 10.1016/S0016-5085(98)70197-0  0.313
1998 Blumberg RS. Current concepts in mucosal immunity. II. One size fits all: nonclassical MHC molecules fulfill multiple roles in epithelial cell function. The American Journal of Physiology. 274: G227-31. PMID 9486173 DOI: 10.1152/Ajpgi.1998.274.2.G227  0.406
1998 Somnay-Wadgaonkar K, Nusrat A, Canchis W, Colgan S, Balk S, Blumberg R. CDld localizes to the apical and lateral cell surface of human intestinal epithelial cells Gastroenterology. 114: A1088. DOI: 10.1016/S0016-5085(98)84424-7  0.367
1998 Somnay-Wadgaonkar K, Nusrat A, Canchis W, Colgan S, Blumberg R. CDld expression on intestinal epithelial cells (IEC) is decreased in inflammatory bowel disease Gastroenterology. 114: A1088. DOI: 10.1016/S0016-5085(98)84423-5  0.427
1998 Morales V, Christ A, Watt S, Russell G, Bahn A, Mizoguchi A, Freeman G, Blumberg R. Biliary glycoprotein (BGP;CD66a) functions as an inhibitory coreceptor for activation of human intestinal intraepithelial lymphocytes (iIEL) Gastroenterology. 114: A1044. DOI: 10.1016/S0016-5085(98)84244-3  0.438
1998 Kim H, Hershberg R, Balk S, Blumberg R. CDld biosynthetic pathway in a transfected T84 cell line Gastroenterology. 114: A1009. DOI: 10.1016/S0016-5085(98)84107-3  0.336
1998 Campbell N, Balk S, Blumberg R, Mayer L. The formation of a novel class Ib:gp180 complex on the surface of intestinal epithelial cells triggers a signaling cascade resulting in the activation of CD8+ suppressor T cells Gastroenterology. 114: A946. DOI: 10.1016/S0016-5085(98)83850-X  0.415
1997 Israel EJ, Taylor S, Wu Z, Mizoguchi E, Blumberg RS, Bhan A, Simister NE. Expression of the neonatal Fc receptor, FcRn, on human intestinal epithelial cells Immunology. 92: 69-74. PMID 9370926 DOI: 10.1046/J.1365-2567.1997.00326.X  0.392
1997 Christ AD, Colgan SP, Balk SP, Blumberg RS. Human intestinal epithelial cell lines produce factor(s) that inhibit CD3-mediated T-lymphocyte proliferation Immunology Letters. 58: 159-165. PMID 9293397 DOI: 10.1016/S0165-2478(97)00081-3  0.372
1997 Blumberg RS, Colgan SP, Balk SP. CD1d: outside-in antigen presentation in the intestinal epithelium? Clinical and Experimental Immunology. 109: 223-225. PMID 9276515 DOI: 10.1046/J.1365-2249.1997.4381336.X  0.362
1997 Christ AD, Blumberg RS. The intestinal epithelial cell: immunological aspects. Springer Seminars in Immunopathology. 18: 449-61. PMID 9144864 DOI: 10.1007/Bf00824052  0.447
1996 Blumberg RS, Gerdes D, Chott A, Porcelli SA, Balk SP. Structure and function of the CD1 family of MHC-like cell surface proteins. Immunological Reviews. 147: 5-29. PMID 8847079 DOI: 10.1111/J.1600-065X.1995.Tb00085.X  0.396
1996 Taplin ME, Frantz ME, Canning C, Ritz J, Blumberg RS, Balk SP. Evidence against T-cell development in the adult human intestinal mucosa based upon lack of terminal deoxynucleotidyltransferase expression. Immunology. 87: 402-7. PMID 8778025 DOI: 10.1046/J.1365-2567.1996.496571.X  0.411
1996 Colgan SP, Morales VM, Madara JL, Polischuk JE, Balk SP, Blumberg RS. IFN-gamma modulates CD1d surface expression on intestinal epithelia. The American Journal of Physiology. 271: C276-83. PMID 8760056 DOI: 10.1152/Ajpcell.1996.271.1.C276  0.42
1996 Balk SP, Polischuk JE, Probert C, Stevens C, Ebert E, She J, Terhorst C, Blumberg RS. Composition of TCR-CD3 complex in human intestinal intraepithelial lymphocytes: lack of Fc epsilon RI gamma chain. International Immunology. 7: 1237-41. PMID 7495730 DOI: 10.1093/Intimm/7.8.1237  0.322
1996 Morales VM, Snapper SB, Blumberg RS. Probing the gastrointestinal immune function using transgenic and knockout technology Current Opinion in Gastroenterology. 12: 577-583. DOI: 10.1097/00001574-199611000-00015  0.339
1995 Blumberg RS, Koss T, Story CM, Barisani D, Polischuk J, Lipin A, Pablo L, Green R, Simister NE. A major histocompatibility complex class I-related Fc receptor for IgG on rat hepatocytes Journal of Clinical Investigation. 95: 2397-2402. PMID 7738203 DOI: 10.1172/Jci117934  0.381
1994 Gross GG, Schwartz VL, Stevens C, Ebert EC, Blumberg RS, Balk SP. Distribution of dominant T cell receptor beta chains in human intestinal mucosa. The Journal of Experimental Medicine. 180: 1337-44. PMID 7931067 DOI: 10.1084/Jem.180.4.1337  0.402
1994 Brandeis JM, Sayegh MH, Gallon L, Blumberg RS, Carpenter CB. Rat intestinal epithelial cells present major histocompatibility complex allopeptides to primed T cells. Gastroenterology. 107: 1537-42. PMID 7926518 DOI: 10.1016/0016-5085(94)90560-6  0.433
1994 Blumberg RS, Balk SP. Intraepithelial lymphocytes and their recognition of non-classical MHC molecules. International Reviews of Immunology. 11: 15-30. PMID 7520051 DOI: 10.3109/08830189409061714  0.444
1994 Balk SP, Burke S, Polischuk JE, Frantz ME, Yang L, Porcelli S, Colgan SP, Blumberg RS. Beta 2-microglobulin-independent MHC class Ib molecule expressed by human intestinal epithelium. Science (New York, N.Y.). 265: 259-62. PMID 7517575 DOI: 10.1126/Science.7517575  0.348
1994 Burke S, Landau S, Green R, Tseng CC, Nattakom T, Canchis W, Yang L, Kaiserlian D, Gespach C, Balk S, Blumberg R. Rat cluster of differentiation 1 molecule: Expression on the surface of intestinal epithelial cells and hepatocytes Gastroenterology. 106: 1143-1149. PMID 7513663 DOI: 10.1016/0016-5085(94)90003-5  0.355
1993 Panja A, Blumberg RS, Balk SP, Mayer L. CD1d is involved in T cell-intestinal epithelial cell interactions. The Journal of Experimental Medicine. 178: 1115-9. PMID 7688787 DOI: 10.1084/Jem.178.3.1115  0.438
1991 Blumberg RS, Sancho J, Ley SC, McDermott FV, Tan KN, Breitmeyer J, Terhorst C. Genetic reconstitution of the T cell receptor (TcR) alpha/beta heterodimer restores the association of CD3 zeta 2 with the TcR/CD3 complex. European Journal of Immunology. 21: 473-81. PMID 1825637 DOI: 10.1002/Eji.1830210233  0.325
1991 Balk SP, Ebert EC, Blumenthal RL, McDermott FV, Wucherpfennig KW, Landau SB, Blumberg RS. Oligoclonal expansion and CD1 recognition by human intestinal intraepithelial lymphocytes. Science (New York, N.Y.). 253: 1411-5. PMID 1716785 DOI: 10.1126/Science.1716785  0.416
1991 Alarcon B, Ley SC, Sanchez-Madrid F, Blumberg RS, Ju ST, Fresno M, Terhorst C. The CD3‐gamma and CD3‐delta subunits of the T cell antigen receptor can be expressed within distinct functional TCR/CD3 complexes. The Embo Journal. 10: 903-912. DOI: 10.1002/J.1460-2075.1991.Tb08023.X  0.343
1990 Blumberg RS, Ley S, Sancho J, Lonberg N, Lacy E, McDermott F, Schad V, Greenstein JL, Terhorst C. Structure of the T-cell antigen receptor: evidence for two CD3 epsilon subunits in the T-cell receptor-CD3 complex. Proceedings of the National Academy of Sciences of the United States of America. 87: 7220-4. PMID 2144901 DOI: 10.1073/Pnas.87.18.7220  0.344
1990 Bleicher PA, Balk SP, Hagen SJ, Blumberg RS, Flotte TJ, Terhorst C. Expression of murine CD1 on gastrointestinal epithelium. Science (New York, N.Y.). 250: 679-82. PMID 1700477 DOI: 10.1126/Science.1700477  0.375
1990 Reno TA, Ley S, Sugiyama E, Cantagrel A, Blumberg R, Bonventre J, Terhorst C, Yeh ET. Defects in signal transduction caused by a T cell receptor beta chain substitution. European Journal of Immunology. 20: 1417-22. PMID 1696890 DOI: 10.1002/Eji.1830200702  0.368
1987 Walker BD, Chakrabarti S, Moss B, Paradis TJ, Flynn T, Durno AG, Blumberg RS, Kaplan JC, Hirsch MS, Schooley RT. HIV-specific cytotoxic T lymphocytes in seropositive individuals. Nature. 328: 345-8. PMID 3496541 DOI: 10.1038/328345A0  0.302
1987 Blumberg RS, Paradis T, Byington R, Henle W, Hirsch MS, Schooley RT. Effects of human immunodeficiency virus on the cellular immune response to Epstein-Barr virus in homosexual men: characterization of the cytotoxic response and lymphokine production. The Journal of Infectious Diseases. 155: 877-90. PMID 3031170 DOI: 10.1093/Infdis/155.5.877  0.338
1986 Kurnick JT, Kradin RL, Blumberg R, Schneeberger EE, Boyle LA. Functional characterization of T lymphocytes propagated from human lung carcinomas. Clinical Immunology and Immunopathology. 38: 367-80. PMID 3080265 DOI: 10.1016/0090-1229(86)90247-3  0.372
1986 Blumberg RS, Sandstrom EG, Paradis TJ, Neumeyer DN, Sarngadharan MG, Hartshorn KL, Byington RE, Hirsch MS, Schooley RT. Detection of human T-cell lymphotropic virus type III-related antigens and anti-human T-cell lymphotropic virus type III antibodies by anticomplementary immunofluorescence. Journal of Clinical Microbiology. 23: 1072-7. PMID 2423552 DOI: 10.1128/Jcm.23.6.1072-1077.1986  0.335
Low-probability matches (unlikely to be authored by this person)
2005 Blumberg RS, Pitman RS, Taylor CT, Colgan SP. Cholera toxin potentiates influences of IFN-gamma through activation of NF-kappaB and release of tumor necrosis factor-alpha. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 25: 209-19. PMID 15812247 DOI: 10.1089/Jir.2005.25.209  0.3
2015 Hosomi S, Kaser A, Blumberg RS. Role of endoplasmic reticulum stress and autophagy as interlinking pathways in the pathogenesis of inflammatory bowel disease. Current Opinion in Gastroenterology. 31: 81-8. PMID 25426970 DOI: 10.1097/Mog.0000000000000144  0.299
2009 Kuo T, de Muinck EJ, Aveson VG, Kobayashi K, Lencer WI, Blumberg RS. S1576 Neonatal FC Receptor in the Liver Mediates Transport of IgG and Albumin from Bile to Circulation Gastroenterology. 136: A-817. DOI: 10.1016/S0016-5085(09)63766-5  0.299
2005 Zhu X, Peng J, Chen D, Liu X, Ye L, Iijima H, Kadavil K, Lencer WI, Blumberg RS. Calnexin and ERp57 facilitate the assembly of the neonatal Fc receptor for IgG with β2-microglobulin in the endoplasmic reticulum Journal of Immunology. 175: 967-976. PMID 16002696 DOI: 10.4049/Jimmunol.175.2.967  0.298
2000 Badizadegan K, Dickinson BL, Wheeler HE, Blumberg RS, Holmes RK, Lencer WI. Heterogeneity of detergent-insoluble membranes from human intestine containing caveolin-1 and ganglioside G(M)1 American Journal of Physiology - Gastrointestinal and Liver Physiology. 278. PMID 10859219 DOI: 10.1152/Ajpgi.2000.278.6.G895  0.298
2019 Lu R, Zhang Y, Blumberg RS, Sun J. 1154 – Lack of Vitamin D Receptor in Paneth Cells Leads to Impaired Anti-Bacterial Ability Gastroenterology. 156: S-247. DOI: 10.1016/S0016-5085(19)37421-9  0.298
2021 Shankman LS, Fleury ST, Evans WB, Penberthy KK, Arandjelovic S, Blumberg RS, Agaisse H, Ravichandran KS. Efferocytosis by Paneth cells within the intestine. Current Biology : Cb. PMID 33852873 DOI: 10.1016/j.cub.2021.03.055  0.298
2017 Dankner M, Gray-Owen SD, Huang YH, Blumberg RS, Beauchemin N. CEACAM1 as a multi-purpose target for cancer immunotherapy. Oncoimmunology. 6: e1328336. PMID 28811966 DOI: 10.1080/2162402X.2017.1328336  0.297
1987 Blumberg RS, Hartshorn KL, Ardman B, Kaplan JC, Paradis T, Vogt M, Hirsch MS, Schooley RT. Dot immunobinding assay for detection of human immunodeficiency virus-associated antigens. Journal of Clinical Microbiology. 25: 1989-92. PMID 3312291 DOI: 10.1128/Jcm.25.10.1989-1992.1987  0.297
2016 Nagaishi T, Tokai A, Watabe T, Jose N, Hosoya A, Yamazaki M, Blumberg RS, Watanabe M. Sa1862 CEACAM1 May Regulate BCR Signaling in the Activated B Cells Gastroenterology. 150: S384. DOI: 10.1016/S0016-5085(16)31351-8  0.294
2005 Mayer L, Blumberg RS. Role of epithelial cells in mucosal antigen presentation Mucosal Immunology, Two-Volume Set. 435-450. DOI: 10.1016/B978-012491543-5/50029-2  0.294
2011 Lu SX, Kappel LW, Charbonneau-Allard AM, Atallah R, Holland AM, Turbide C, Hubbard VM, Rotolo JA, Smith M, Suh D, King C, Rao UK, Yim N, Bautista JL, Jenq RR, ... ... Blumberg RS, et al. Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation. Plos One. 6: e21611. PMID 21760897 DOI: 10.1371/Journal.Pone.0021611  0.294
2020 Matute JD, Duan J, Blumberg RS. Microbial RNAs Pressure Piezo1 to Respond. Cell. 182: 542-544. PMID 32763186 DOI: 10.1016/J.Cell.2020.07.015  0.291
2000 Omata F, Birkenbach M, Matsuzaki S, Blumberg RS. Characterization of epstein-barr virus induced gene 3 MRNA expression relative to the expression of the IL-12P40 subunit in human inflammatory bowel disease Gastroenterology. 118: A113. DOI: 10.1016/S0016-5085(00)82530-5  0.291
2001 Perez A, Blumberg R, Grikscheit T, Ashley S, Vacanti J, Whang E. Tissue-engineered small intestine: Ontogeny of the immune system Current Surgery. 58: 560-561. DOI: 10.1016/S0149-7944(01)00552-9  0.29
2005 Zahn S, Wirtz S, Birkenbach M, Blumberg RS, Neurath MF, von Stebut E. Impaired Th1 responses in mice deficient in Epstein-Barr virus-induced gene 3 and challenged with physiological doses of Leishmania major. European Journal of Immunology. 35: 1106-12. PMID 15756639 DOI: 10.1002/Eji.200425926  0.29
2014 Zeissig S, Blumberg RS. Life at the beginning: perturbation of the microbiota by antibiotics in early life and its role in health and disease. Nature Immunology. 15: 307-10. PMID 24646587 DOI: 10.1038/Ni.2847  0.289
2016 Peuker K, Muff S, Wang J, Zeißig Y, Strigli A, Kaser A, Arlt A, Schafmayer C, Egberts J, Becker T, Röcken C, Hampe J, Schreiber S, Baines J, Blumberg R, et al. Intestinal-epitheliales Calcineurin in der Mikrobiota-abhängigen Regulation des kolorektalen Karzinoms Zeitschrift FüR Gastroenterologie. 54. DOI: 10.1055/S-0036-1587144  0.289
2023 Duan J, Matute JD, Unger LW, Hanley T, Schnell A, Lin X, Krupka N, Griebel P, Lambden C, Sit B, Grootjans J, Pyzik M, Sommer F, Kaiser S, Falk-Paulsen M, ... ... Blumberg RS, et al. Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut. Immunity. PMID 36917985 DOI: 10.1016/j.immuni.2023.02.018  0.288
2012 Ben Suleiman Y, Yoshida M, Nishiumi S, Tanaka H, Mimura T, Nobutani K, Yamamoto K, Takenaka M, Aoganghua A, Miki I, Ota H, Takahashi S, Matsui H, Nakamura M, Blumberg RS, et al. Neonatal Fc receptor for IgG (FcRn) expressed in the gastric epithelium regulates bacterial infection in mice. Mucosal Immunology. 5: 87-98. PMID 22089027 DOI: 10.1038/Mi.2011.53  0.288
2023 Duan J, Sun Y, Matute JD, Blumberg RS. Characterizing CD4 T cell differentiation in mouse small intestine using T cell transfer, lamina propria preparation, and flow cytometry. Star Protocols. 4: 102485. PMID 37566548 DOI: 10.1016/j.xpro.2023.102485  0.288
2016 Vitenshtein A, Weisblum Y, Hauka S, Halenius A, Oiknine-Djian E, Tsukerman P, Bauman Y, Bar-On Y, Stern-Ginossar N, Enk J, Ortenberg R, Tai J, Markel G, Blumberg RS, Hengel H, et al. CEACAM1-Mediated Inhibition of Virus Production. Cell Reports. PMID 27264178 DOI: 10.1016/J.Celrep.2016.05.036  0.286
2016 Lin JE, Colon-Gonzalez F, Blomain E, Kim GW, Aing A, Stoecker B, Rock J, Snook AE, Zhan T, Hyslop TM, Tomczak M, Blumberg RS, Waldman SA. Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis. Cancer Research. 76: 339-346. PMID 26773096 DOI: 10.1158/0008-5472.Can-15-1467-T  0.285
2001 Watt SM, Teixeira AM, Zhou GQ, Doyonnas R, Zhang Y, Grunert F, Blumberg RS, Kuroki M, Skubitz KM, Bates PA. Homophilic adhesion of human CEACAM1 involves N-terminal domain interactions: structural analysis of the binding site. Blood. 98: 1469-79. PMID 11520797 DOI: 10.1182/Blood.V98.5.1469  0.285
2005 Arita M, Yoshida M, Hong S, Tjonahen E, Glickman JN, Petasis NA, Blumberg RS, Serhan CN. Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis Proceedings of the National Academy of Sciences of the United States of America. 102: 7671-7676. PMID 15890784 DOI: 10.1073/Pnas.0409271102  0.285
2016 Mudde AC, Lexmond WS, Blumberg RS, Nurko S, Fiebiger E. Eosinophilic esophagitis: published evidences for disease subtypes, indications for patient subpopulations, and how to translate patient observations to murine experimental models. The World Allergy Organization Journal. 9: 23. PMID 27458501 DOI: 10.1186/S40413-016-0114-3  0.285
2016 Aden K, Tran F, Tschurtschenthaler M, Bartsch K, Terzerji RS, Luzius A, Paulsen M, Kuiper J, Rabe B, Blumberg RS, Schreiber S, Kaser A, Rosenstiel P. 432 ATG16L1 and XBP1 Coordinate Interleukin 22 Dependent Signals in Intestinal Epithelium Gastroenterology. 150: S90. DOI: 10.1016/S0016-5085(16)30417-6  0.284
2017 Blumberg L, Humphries JE, Lasseter KC, Blumberg RS. SYNT001: A Humanized IgG4 Monoclonal Antibody That Disrupts the Interaction of FcRn and IgG for the Treatment of IgG-Mediated Autoimmune Diseases Blood. 130: 3483-3483. DOI: 10.1182/Blood.V130.Suppl_1.3483.3483  0.284
2020 Jackson DN, Panopoulos M, Neumann WL, Turner K, Cantarel BL, Thompson-Snipes L, Dassopoulos T, Feagins LA, Souza RF, Mills JC, Blumberg RS, Venuprasad K, Thompson WE, Theiss AL. Mitochondrial dysfunction during loss of prohibitin 1 triggers Paneth cell defects and ileitis. Gut. PMID 32111635 DOI: 10.1136/Gutjnl-2019-319523  0.284
2012 Olszak T, An D, Zeissig S, Vera MP, Glickman J, Baron RM, Kasper DL, Blumberg RS. Tu1962 Microbial Exposure During Early Life Has Persistent Effects on Tissue-Associated iNKT Cells and Their Function Gastroenterology. 142: S-887. DOI: 10.1016/S0016-5085(12)63449-0  0.283
2005 Blumberg RS, Lencer WI. Antibodies in the breakdown lane Nature Biotechnology.. 23: 1232-1234. PMID 16211062 DOI: 10.1038/Nbt1005-1232  0.282
2021 Chen Z, Luo J, Li J, Kim G, Chen ES, Xiao S, Snapper SB, Bao B, An D, Blumberg RS, Lin CH, Wang S, Zhong J, Liu K, Li Q, et al. Foxo1 controls gut homeostasis and commensalism by regulating mucus secretion. The Journal of Experimental Medicine. 218. PMID 34287641 DOI: 10.1084/jem.20210324  0.281
2010 Kamat A, Ancuta P, Blumberg RS, Gabuzda D. Serological markers for inflammatory bowel disease in AIDS patients with evidence of microbial translocation. Plos One. 5: e15533. PMID 21125014 DOI: 10.1371/Journal.Pone.0015533  0.281
2000 Badizadegan K, Dickinson BL, Wheeler HE, Holmes RK, Blumberg RS, Lencer WI. Heterogeneity of detergent-insoluble membranes from human intestinal epithelia containing caveolin-1 and ganglioside GM1 Gastroenterology. 118: A596. DOI: 10.1016/S0016-5085(00)84524-2  0.281
2014 Kaser A, Blumberg RS. ATG16L1 Crohn's disease risk stresses the endoplasmic reticulum of Paneth cells. Gut. 63: 1038-9. PMID 24304670 DOI: 10.1136/Gutjnl-2013-306103  0.28
2012 Tomczak M, Ko H, Adolph T, Flak MB, Martinez-Naves E, Hosomi S, Glickman J, Kaser A, Blumberg RS. 631 Impaired Autophagy Promotes ER Stress Induced Intestinal Inflammation Gastroenterology. 142: S-124-S-125. DOI: 10.1016/S0016-5085(12)60471-5  0.279
2004 Wada K, Nakajima A, Takahashi H, Yoneda M, Fujisawa N, Ohsawa E, Kadowaki T, Kubota N, Terauchi Y, Matsuhashi N, Saubermann LJ, Nakajima N, Blumberg RS. Protective effect of endogenous PPARγ against acute gastric mucosal lesions associated with ischemia-reperfusion American Journal of Physiology - Gastrointestinal and Liver Physiology. 287: G452-G458. PMID 15246971 DOI: 10.1152/Ajpgi.00523.2003  0.279
2008 Wirtz SJ, Becker C, Blumberg RS, Neurath MF. 20 EBI3, a Component of the Regulatory Cytokines IL-27 and IL-35, Contributes to Protective Colonic Immune Responses in Experimental Colitis Gastroenterology. 134: A-2. DOI: 10.1016/S0016-5085(08)60016-5  0.278
2012 Blumberg R, Powrie F. Microbiota, disease, and back to health: A metastable journey Science Translational Medicine. 4. PMID 22674557 DOI: 10.1126/Scitranslmed.3004184  0.277
1987 Blumberg RS, Paradis T, Hartshorn KL, Vogt M, Ho DD, Hirsch MS, Leban J, Sato VL, Schooley RT. Antibody-dependent cell-mediated cytotoxicity against cells infected with the human immunodeficiency virus. The Journal of Infectious Diseases. 156: 878-84. PMID 3479500 DOI: 10.1093/Infdis/156.6.878  0.277
2023 Pyzik M, Kozicky LK, Gandhi AK, Blumberg RS. The therapeutic age of the neonatal Fc receptor. Nature Reviews. Immunology. 1-18. PMID 36726033 DOI: 10.1038/s41577-022-00821-1  0.276
2008 Blumberg RS, Li L, Nusrat A, Parkos CA, Rubin DC, Carrington JL. Recent insights into the integration of the intestinal epithelium within the mucosal environment in health and disease. Mucosal Immunology. 1: 330-4. PMID 19079196 DOI: 10.1038/Mi.2008.29  0.276
1987 Blumberg RS, Paradis TJ, Crawford D, Byington RE, Hirsch MS, Schooley RT. Effects of human immunodeficiency virus (HIV) on the cytotoxic response to Epstein Barr virus (EBV) transformed B lymphocytes. Aids Research and Human Retroviruses. 3: 303-15. PMID 2829951 DOI: 10.1089/Aid.1987.3.303  0.275
2022 Matute JD, Duan J, Flak MB, Griebel P, Tascon-Arcila JA, Doms S, Hanley T, Antanaviciute A, Gundrum J, Mark Welch JL, Sit B, Abtahi S, Fuhler GM, Grootjans J, Tran F, ... ... Blumberg RS, et al. Intelectin-1 binds and alters the localization of the mucus barrier-modifying bacterium Akkermansia muciniphila. The Journal of Experimental Medicine. 220. PMID 36413219 DOI: 10.1084/jem.20211938  0.27
1999 Kim HS, Garcia J, Exley M, Johnson KW, Balk SP, Blumberg RS. Biochemical characterization of CD1d expression in the absence of β2- microglobulin Journal of Biological Chemistry. 274: 9289-9295. PMID 10092605 DOI: 10.1074/jbc.274.14.9289  0.27
1995 Blumberg RS. An antigen shared by Colon, eye, and joint and relevance for ulcerative colitis Inflammatory Bowel Diseases. 1: 88-89. PMID 23283314 DOI: 10.1097/00054725-199503000-00014  0.268
2000 Pitman RS, Taylor CT, Blumberg RS, Colgan SP. Cholera toxin elicits epithelial TNF production; Potential role in adjuvant activity Gastroenterology. 118: A102. DOI: 10.1016/S0016-5085(00)82486-5  0.268
2003 Nagaishi T, Iijima H, Pao L, Glickman JN, Glimcher LH, Neel BG, Blumberg RS. SHP-1 dependent and independent suppression of colitis by a CEACAM1 isoform expressing a long cytoplasmic tail Gastroenterology. 124: A35. DOI: 10.1016/S0016-5085(03)80173-7  0.265
2021 Oh SF, Praveena T, Song H, Yoo JS, Jung DJ, Erturk-Hasdemir D, Hwang YS, Lee CC, Le Nours J, Kim H, Lee J, Blumberg RS, Rossjohn J, Park SB, Kasper DL. Host immunomodulatory lipids created by symbionts from dietary amino acids. Nature. PMID 34759313 DOI: 10.1038/s41586-021-04083-0  0.264
1998 Roberts A, Blumberg R, Ebert E. Staphylococcal enterotoxin B (SEB) induces different mechanisms of lytic activity by jejunal intraepithelial lymphocytes (IELs) Gastroenterology. 114: A1069. DOI: 10.1016/S0016-5085(98)84350-3  0.264
2013 Pridgen EM, Alexis F, Kuo TT, Levy-Nissenbaum E, Karnik R, Blumberg RS, Langer R, Farokhzad OC. Transepithelial transport of Fc-targeted nanoparticles by the neonatal fc receptor for oral delivery. Science Translational Medicine. 5: 213ra167. PMID 24285486 DOI: 10.1126/Scitranslmed.3007049  0.264
1990 Blumberg RS. Relapse of chronic inflammatory bowel disease : a riddle wrapped in a mystery inside an enigma Gastroenterology. 98: 792-796. PMID 2404829 DOI: 10.1016/0016-5085(90)90305-K  0.263
1995 Kim HS, Morales VM, Dass C, Encinas J, Teitell M, Blumberg RS. Cloning of the gene encoding the mouse homologue of the human calcium signal-modulating ligand Gene. 163: 323-324. PMID 7590290 DOI: 10.1016/0378-1119(95)00393-K  0.262
1990 Blumberg RS. Relapse of chronic inflammatory bowel disease Gastroenterology. 98: 792-796. DOI: 10.5555/Uri:Pii:001650859090305K  0.262
1999 Hershberg RM, Blumberg RS. What's so (co)stimulating about the intestinal epithelium? Gastroenterology. 117: 726-736. PMID 10464150 DOI: 10.1016/S0016-5085(99)70467-1  0.26
2010 Fritz T, Niederreiter L, Tilg H, Blumberg RS, Kaser A. Controversy over NOD2, inflammation, and defensins. Inflammatory Bowel Diseases. 16: 1996-8. PMID 20128000 DOI: 10.1002/Ibd.21213  0.258
2012 Khatun I, Zeissig S, Iqbal J, Wang M, Curiel D, Shelness GS, Blumberg RS, Hussain MM. Phospholipid transfer activity of microsomal triglyceride transfer protein produces apolipoprotein B and reduces hepatosteatosis while maintaining low plasma lipids in mice. Hepatology (Baltimore, Md.). 55: 1356-68. PMID 22121032 DOI: 10.1002/Hep.25504  0.258
2021 Gensollen T, Lin X, Zhang T, Pyzik M, See P, Glickman JN, Ginhoux F, Waldor M, Salmi M, Rantakari P, Blumberg RS. Embryonic macrophages function during early life to determine invariant natural killer T cell levels at barrier surfaces. Nature Immunology. 22: 699-710. PMID 34040226 DOI: 10.1038/s41590-021-00934-0  0.257
2008 Tzaban S, Yen EH, Wagner J, Goldenring JR, Blumberg RS, Lencer WI. S1768 Mapping the Intracellular Itinerary of FcRn-Dependent IgG Transport Across Mucosal Surfaces Gastroenterology. 134: A-266. DOI: 10.1016/S0016-5085(08)61236-6  0.256
1987 Hartshorn KL, Vogt MW, Chou TC, Blumberg RS, Byington R, Schooley RT, Hirsch MS. Synergistic inhibition of human immunodeficiency virus in vitro by azidothymidine and recombinant alpha A interferon. Antimicrobial Agents and Chemotherapy. 31: 168-72. PMID 3471180 DOI: 10.1128/Aac.31.2.168  0.255
2002 Zhu X, Peng J, Raychowdhury R, Nakajima A, Lencer WI, Blumberg RS. The heavy chain of neonatal Fc receptor for IgG is sequestered in endoplasmic reticulum by forming oligomers in the absence of beta2-microglobulin association. The Biochemical Journal. 367: 703-14. PMID 12162790 DOI: 10.1042/Bj20020200  0.254
2011 Blumberg R, Cho J, Lewis J, Wu G. Inflammatory bowel disease: An update on the fundamental biology and clinical management Gastroenterology. 140: 1701-1703. PMID 21530735 DOI: 10.1053/J.Gastro.2011.03.013  0.253
2004 Matsumoto T, Nieuwenhuis EES, Cisneros RL, Ruiz-Perez B, Yamaguchi K, Blumberg RS, Onderdonk AB. Protective effect of ethyl-3-(3-dimethyl aminopropyl)urea dihydrochloride (EDU) against LPS-induced death in mice Journal of Medical Microbiology. 53: 97-102. PMID 14729928 DOI: 10.1099/Jmm.0.05386-0  0.252
2021 Nagaishi T, Watabe T, Kotake K, Kumazawa T, Aida T, Tanaka K, Ono R, Ishino F, Usami T, Miura T, Hirakata S, Kawasaki H, Tsugawa N, Yamada D, Hirayama K, ... ... Blumberg RS, et al. Immunoglobulin A-specific deficiency induces spontaneous inflammation specifically in the ileum. Gut. PMID 33963042 DOI: 10.1136/gutjnl-2020-322873  0.251
1984 Blumberg RS, Kelsey P, Perrone T, Dickersin R, Laquaglia M, Ferruci J. Cytomegalovirus- and Cryptosporidium-associated acalculous gangrenous cholecystitis. The American Journal of Medicine. 76: 1118-1123. PMID 6328993 DOI: 10.1016/0002-9343(84)90868-4  0.245
2001 Saubermann LJ, Wada K, Zhao S, Nakajima A, Blumberg RS, Matsuhashi N. PPARγ ligands are preventive in a murine model of colitis in a dose and cytokine dependent fashion Gastroenterology. 120: A690. DOI: 10.1016/S0016-5085(08)83433-6  0.245
2012 Zeissig S, Murata K, Sweet L, Arlt A, Moody D, Schreiber S, Liang J, Blumberg R. Die Hepatitis B-Virus-Infektion führt zu frühen Veränderungen des hepatozellulären Lipidmilieus und CD1d-vermittelter Präsentation antigener Lysophospholipide Zeitschrift FüR Gastroenterologie. 50. DOI: 10.1055/S-0032-1323985  0.244
2008 Sugimoto K, Shimomura Y, Ogawa A, Andoh A, Bhan AK, Xavier RJ, Blumberg RS, Mizoguchi A. S1751 Establishment of Local Gene Delivery Approach Capable of Targeting Inflamed Mucosa for Activating Innate Responses Gastroenterology. 134: A-262-A-263. DOI: 10.1016/S0016-5085(08)61221-4  0.241
2012 Blumberg RS, Dittel B, Hafler D, von Herrath M, Nestle FO. Unraveling the autoimmune translational research process layer by layer. Nature Medicine. 18: 35-41. PMID 22227670 DOI: 10.1038/Nm.2632  0.24
1986 Blumberg RS, Sandstrom EG, Paradis TJ, Neumeyer DN, Sarngadharan MG, Hartshorn KL, Byington RE, Hirsch MS, Schooley RT. Detection of human T-cell lymphotropic virus type III-related antigens and anti-human T-cell lymphotropic virus type III antibodies by anticomplementary immunofluorescence. Journal of Clinical Microbiology. 23: 1072-1077. DOI: 10.1128/jcm.23.6.1072-1077.1986  0.238
2022 Vobořil M, Březina J, Brabec T, Dobeš J, Ballek O, Dobešová M, Manning J, Blumberg RS, Filipp D. A model of preferential pairing between epithelial and dendritic cells in thymic antigen transfer. Elife. 11. PMID 35099391 DOI: 10.7554/eLife.71578  0.237
2000 Muehlhoefer A, Saubermann LJ, Gu X, Luedtke-Heckenkamp K, Xavier R, Blumberg RS, Podolsky DK, MacDermott RP. Fractalkine is an epithelial and endothelial cell derived chemoattractant for intraepithelial lymphocytes in the small intestinal mucosa Gastroenterology. 118: A111. DOI: 10.1016/S0016-5085(00)82524-X  0.236
2023 Martín-Adrados B, Wculek SK, Fernández-Bravo S, Torres-Ruiz R, Valle-Noguera A, Gomez-Sánchez MJ, Hernández-Walias JC, Ferreira FM, Corraliza AM, Sancho D, Esteban V, Rodriguez-Perales S, Cruz-Adalia A, Nakaya HI, Salas A, ... ... Blumberg RS, et al. Expression of HMGCS2 in intestinal epithelial cells is downregulated in inflammatory bowel disease associated with endoplasmic reticulum stress. Frontiers in Immunology. 14: 1185517. PMID 37457727 DOI: 10.3389/fimmu.2023.1185517  0.236
2023 Alula KM, Dowdell AS, LeBere B, Lee JS, Levens CL, Kuhn KA, Kaipparettu BA, Thompson WE, Blumberg RS, Colgan SP, Theiss AL. Interplay of gut microbiota and host epithelial mitochondrial dysfunction is necessary for the development of spontaneous intestinal inflammation in mice. Microbiome. 11: 256. PMID 37978573 DOI: 10.1186/s40168-023-01686-9  0.235
2009 Lu S, Willis L, Charbonneau-Allard A, Atallah R, Holland A, Turbide C, Hubbard V, Rotolo J, Smith O, Suh D, King C, Rao U, Yim N, Kochman A, Bautista J, ... ... Blumberg R, et al. Ceacam1 Regulates Experimental Graft-Versus-Host-Disease Biology of Blood and Marrow Transplantation. 15: 13. DOI: 10.1016/J.Bbmt.2008.12.038  0.234
2008 Kaser A, Chen Z, Liang TJ, Kim HS, Cohen DE, Blumberg RS. S1734 Apolipoprotein C3 Is a Novel Binding Partner of CD1D and Regulates CD1D-Restricted Immunopathologies Gastroenterology. 134: A-259. DOI: 10.1016/S0016-5085(08)61205-6  0.232
2023 Kojima H, Kadono K, Hirao H, Dery KJ, Torgerson T, Yao S, Kaldas FM, Farmer DG, Blumberg RS, Kupiec-Weglinski JW. T cell CEACAM1 - TIM-3 crosstalk alleviates liver transplant injury in mice and humans. Gastroenterology. PMID 37479191 DOI: 10.1053/j.gastro.2023.07.004  0.231
2013 Flak MB, Neves JF, Blumberg RS. Immunology. Welcome to the microgenderome. Science (New York, N.Y.). 339: 1044-5. PMID 23449586 DOI: 10.1126/Science.1236226  0.231
2015 Baker K, Blumberg RS, Kaetzel CS. Immunoglobulin Transport and Immunoglobulin Receptors Mucosal Immunology: Fourth Edition. 1: 349-407. DOI: 10.1016/B978-0-12-415847-4.00019-7  0.23
1995 Michie CA, Blumberg R. Group B streptococcal infection: when does vertical transmission take place? Archives of Disease in Childhood-Fetal and Neonatal Edition. 73. PMID 7552598 DOI: 10.1136/Fn.73.1.F46  0.229
2022 Lin X, Gaudino SJ, Jang KK, Bahadur T, Singh A, Banerjee A, Beaupre M, Chu T, Wong HT, Kim CK, Kempen C, Axelrad J, Huang H, Khalid S, Shah V, ... ... Blumberg R, et al. IL-17RA-signaling in Lgr5 intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity. PMID 35081371 DOI: 10.1016/j.immuni.2021.12.016  0.229
2018 Nguyen S, Baker K, Padman BS, Patwa R, Dunstan RA, Weston TA, Schlosser K, Bailey B, Lithgow T, Lazarou M, Luque A, Rohwer F, Blumberg RS, Barr JJ. Correction for Nguyen et al., "Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers". Mbio. 9. PMID 29295916 DOI: 10.1128/Mbio.02207-17  0.228
2015 Wirtz S, Becker C, Fantini M, Tubbe I, Blumberg R, Galle P, Neurath M. Die spezifische Expression des Colitis Ulcerosa assoziierten Zytokins EBI3 in Makrophagen und Dendritischen Zellen wird durch bakterielle Komponenten differentiell reguliert Zeitschrift FüR Gastroenterologie. 41. DOI: 10.1055/S-0035-1555263  0.227
2020 Gaudino SJ, Beaupre M, Lin X, Joshi P, Rathi S, McLaughlin PA, Kempen C, Mehta N, Eskiocak O, Yueh B, Blumberg RS, van der Velden AWM, Shroyer KR, Bialkowska AB, Beyaz S, et al. IL-22 receptor signaling in Paneth cells is critical for their maturation, microbiota colonization, Th17-related immune responses, and anti-Salmonella immunity. Mucosal Immunology. PMID 33060802 DOI: 10.1038/s41385-020-00348-5  0.227
2010 Kaser A, Zeissig S, Blumberg RS. Inflammatory bowel disease. Annual Review of Immunology. 28: 573-621. PMID 20192811 DOI: 10.1146/annurev-immunol-030409-101225  0.226
2012 Tomczak MF, Kaser A, Blumberg RS. ER stress in intestinal inflammatory disease Endoplasmic Reticulum Stress in Health and Disease. 2147483647: 281-298. DOI: 10.1007/978-94-007-4351-9_12  0.224
2016 Tran F, Aden K, Tschurtschenthaler M, Sheibani-Tezerji R, Kuiper J, Luzius A, Jentzsch M, Schreiber S, Blumberg R, Kaser A, Rosenstiel P. Das Zusammenspiel aus Autophagie und ER-Stress koordiniert protektive IL-22-Signale im intestinalen Epithel Zeitschrift FüR Gastroenterologie. 54. DOI: 10.1055/S-0036-1586793  0.223
2006 Wirtz S, Tubbe I, Galle P, Blumberg R, Neurath M. Eine wichtige pathogene Rolle des heterogdimeren Zytokins IL-27 bei der septischen Peritonitis Zeitschrift FüR Gastroenterologie. 44. DOI: 10.1055/S-2006-950630  0.219
2023 Duan J, Matute JD, Blumberg RS. IL-22: Immunity's bittersweet symphony. The Journal of Experimental Medicine. 220. PMID 37695524 DOI: 10.1084/jem.20231210  0.217
2022 Mead BE, Hattori K, Levy L, Imada S, Goto N, Vukovic M, Sze D, Kummerlowe C, Matute JD, Duan J, Langer R, Blumberg RS, Ordovas-Montanes J, Yilmaz ÖH, Karp JM, et al. Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation. Nature Biomedical Engineering. PMID 35314801 DOI: 10.1038/s41551-022-00863-9  0.212
2009 Cominelli F, Arseneau KO, Blumberg RS, Stenson WF, Pizarro TT. The Mucosal Immune System and Gastrointestinal Inflammation Textbook of Gastroenterology, Fifth Edition. 1: 133-168. DOI: 10.1002/9781444303254.ch7  0.207
2008 Wirtz S, Becker C, Weigmann B, Galle P, Blumberg R, Neurath M. Untersuchungen zur Rolle der heterodimeren Zytokine IL-27 and IL-35 im Rahmen intestinaler Entzündungsreaktionen Zeitschrift FüR Gastroenterologie. 46. DOI: 10.1055/S-0028-1089575  0.206
2007 Wirtz S, Tubbe I, Becker C, Weigmann B, Lehr H, Galle P, Blumberg R, Neurath M. Die Rolle des immunregulatorischen Zytokins IL-27 bei der DSS Kolitis Zeitschrift FüR Gastroenterologie. 45. DOI: 10.1055/S-2007-988360  0.205
2021 Tsugawa N, Yamada D, Watabe T, Onizawa M, Wang S, Nemoto Y, Oshima S, Tsubata T, Adachi T, Kawano Y, Watanabe M, Blumberg RS, Okamoto R, Nagaishi T. Corrigendum to "CEACAM1 specifically suppresses B cell receptor signaling-mediated activation". Biochemical and Biophysical Research Communications. PMID 33994162 DOI: 10.1016/j.bbrc.2021.05.006  0.202
2012 Diegelmann J, Olszak T, Göke B, Blumberg R, Brand S. P044 Identification of a novel role for interleukin-27 as mediator of intestinal epithelial barrier protection acting via differential STAT signalling and induction of antibacterial and anti-inflammatory proteins Journal of Crohn's and Colitis. 6: S28. DOI: 10.1016/S1873-9946(12)60065-8  0.2
1993 Blumberg RS, Compton CC. A 50-year-old man with the onset of fever and diarrhea in Morocco The New England Journal of Medicine. 329: 561-568. PMID 8336757 DOI: 10.1056/Nejm199308193290809  0.199
2012 Johansen FE, Massol R, Baker K, Fiebiger E, Blumberg RS, Lencer WI. Biology of Gut Immunoglobulins Physiology of the Gastrointestinal Tract. 1: 1089-1118. DOI: 10.1016/B978-0-12-382026-6.00039-7  0.199
1984 Geldelman D, Blumberg R, Sadun A. Ocular Loa Loa with cryoprobe extraction of subconjunctival worm. Ophthalmology. 91: 300-3. PMID 6585771 DOI: 10.1016/S0161-6420(84)34302-0  0.197
1988 Blumberg RS, Chopra S, Ibrahim R, Crawford J, Farraye FA, Zeldis JB, Berman MD. Primary hepatocellular carcinoma in idiopathic hemochromatosis after reversal of cirrhosis. Gastroenterology. 95: 1399-1402. PMID 2844622 DOI: 10.1016/0016-5085(88)90379-4  0.195
2020 Lu R, Zhang Y, Xia Y, Zhang J, Kaser A, Blumberg R, Sun J. Paneth cell alertness to pathogens maintained by vitamin D receptors. Gastroenterology. PMID 33217447 DOI: 10.1053/j.gastro.2020.11.015  0.185
2022 Schwärzler J, Mayr L, Vila AV, Grabherr F, Niederreiter L, Philipp M, Grander C, Meyer M, Jukic A, Tröger S, Enrich B, Przysiecki N, Tschurtschenthaler M, Sommer F, Kronberger I, ... ... Blumberg RS, et al. PUFA-induced metabolic enteritis as a fuel for Crohn's disease. Gastroenterology. PMID 35031299 DOI: 10.1053/j.gastro.2022.01.004  0.184
1963 Boris M, Blumberg R, Feldman DB, Sellers TF. Increased Incidence of Meningomyeloceles Jama: the Journal of the American Medical Association. 184: 768. DOI: 10.1001/Jama.1963.73700230001011  0.183
2018 Werth V, Culton D, Blumberg L, Humphries J, Blumberg R, Hall R. 538 FcRn blockade with SYNT001 for the treatment of pemphigus Journal of Investigative Dermatology. 138: S92. DOI: 10.1016/J.Jid.2018.03.546  0.183
2006 Blumberg RS. Presentation of the Julius M. Friedenwald Medal to Norton J. Greenberger, MD Gastroenterology. 130: 2210-2214. PMID 16762642 DOI: 10.1053/J.Gastro.2006.04.041  0.183
2007 Kaser A, Lee A, Glickman J, Tilg H, Nieuwenhuis E, Higgins D, Glimcher L, Blumberg R. O01 TRANSCRIPTION FACTOR XBP1 REGULATES PANETH CELL FUNCTION AND INFLAMMATION IN THE INTESTINE Journal of Crohn's and Colitis Supplements. 1: 1-2. DOI: 10.1016/S1873-9954(07)70003-4  0.182
2014 Baker K, Rath T, Blumberg RS. Regulation of immunological responses by the neonatal Fc receptor for IgG, FcRn Molecular and Cellular Mechanisms of Antibody Activity. 189-219. DOI: 10.1007/978-1-4614-7107-3_8  0.179
2021 Werth VP, Culton DA, Concha JSS, Graydon JS, Blumberg LJ, Okawa J, Pyzik M, Blumberg RS, Hall RP. Safety, Tolerability, and Activity of ALXN1830 Targeting the Neonatal Fc Receptor in Chronic Pemphigus. The Journal of Investigative Dermatology. PMID 34126109 DOI: 10.1016/j.jid.2021.04.031  0.178
2010 Kaser A, Lee A, Franke A, Glickman J, Zeissig S, Schreiber S, Glimcher L, Blumberg R. E09 ER stress, paneth cells and intestinal inflammation Journal of Crohn's and Colitis Supplements. 4: 8-9. DOI: 10.1016/S1873-9954(10)70013-6  0.178
2005 Wirtz S, Tubbe I, Blumberg R, Galle P, Neurath M. IL–27 als wichtiger Effektor der systemischen Entzündung bei der septischen Peritonitis Zeitschrift FüR Gastroenterologie. 43. DOI: 10.1055/S-2005-919909  0.177
2011 Yang VW, Blumberg RS. "What color is my parachute": career opportunities in academic gastroenterology and hepatology. Gastroenterology. 141: 1138-41. PMID 21864476 DOI: 10.1053/J.Gastro.2011.08.027  0.175
1982 Weniger BG, Blumberg RS, Campbell CC, Jones TC, Mount DL, Friedman SM. High-level chloroquine resistance of Plasmodium falciparum malaria acquired in Kenya. The New England Journal of Medicine. 307: 1560-2. PMID 6755252 DOI: 10.1056/Nejm198212163072506  0.174
2020 Rayes RF, Vourtzoumis P, Bou Rjeily M, Seth R, Bourdeau F, Giannias B, Berube J, Huang YH, Rousseau S, Camilleri-Broet S, Blumberg RS, Beauchemin N, Najmeh S, Cools-Lartigue J, Spicer JD, et al. Neutrophil Extracellular Trap-Associated CEACAM1 as a Putative Therapeutic Target to Prevent Metastatic Progression of Colon Carcinoma. Journal of Immunology (Baltimore, Md. : 1950). PMID 32169849 DOI: 10.4049/jimmunol.1900240  0.172
2009 Cooney R, Jewell D, Papadakis KA, Skrypnyk IN, Zeitz M, Shen L, Su L, Turner JR, Hering NA, Schulzke J, Blumberg RS, Siegmund B, Vatn MH, Dietrich CF, Marth T, et al. Subject Index Vol. 27, 2009 Digestive Diseases. 27: 597-598. DOI: 10.1159/000257417  0.171
2009 Cooney R, Jewell D, Papadakis KA, Skrypnyk IN, Zeitz M, Shen L, Su L, Turner JR, Hering NA, Schulzke J, Blumberg RS, Siegmund B, Vatn MH, Dietrich CF, Marth T, et al. Contents Vol. 27, 2009 Digestive Diseases. 27. DOI: 10.1159/000257418  0.17
1961 Nahmias A, Sakurai N, Blumberg R, Doege A, Sulzer C. The Staphylococcus “80/81 Complex”: Epidemiological and Laboratory Observations The Journal of Infectious Diseases. 109: 211-222. PMID 14477984 DOI: 10.1093/Infdis/109.3.211  0.169
1999 Blumberg RS. The leadership of innovation. Gastroenterology. 116: 787. PMID 10206783 DOI: 10.1016/S0016-5085(99)70059-4  0.169
2000 Blumberg RS. David and Goliath: discovery in the industrial age of science. Gastroenterology. 119: 5. PMID 10889148 DOI: 10.1016/S0016-5085(00)70053-9  0.167
2009 Chen Z, Chen L, Blumberg RS. Editorial: CEACAM1: fine-tuned for fine-tuning. Journal of Leukocyte Biology. 86: 195-7. PMID 19643737 DOI: 10.1189/Jlb.0309122  0.167
2008 Strober W, Zeitz M, Blumberg RS. Mechanisms of intestinal inflammation. Preface. Mucosal Immunology. 1: S1-4. PMID 19079219 DOI: 10.1038/mi.2008.58  0.165
2020 Blumberg RS. Norton Greenberger, MD, MACP- September 13, 1933-March 21, 2020. Gastroenterology. PMID 32585143 DOI: 10.1053/J.Gastro.2020.04.060  0.163
2023 Brabec T, Vobořil M, Schierova D, Valter E, Splichalova I, Dobeš J, Brezina J, Dobesova M, Aidarova A, Jakubec M, Manning J, Blumberg R, Waissman A, Kolar M, Kubovciak J, et al. IL-17 driven induction of Paneth cell antimicrobial functions protects the host from microbiota dysbiosis and inflammation in the ileum. Mucosal Immunology. PMID 36739089 DOI: 10.1016/j.mucimm.2023.01.005  0.155
2021 Welz L, Kakavand N, Hang X, Laue G, Ito G, Silva MG, Plattner C, Mishra N, Tengen F, Ogris C, Jesinghaus M, Wottawa F, Arnold P, Kaikkonen L, Stengel S, ... ... Blumberg R, et al. Epithelial XBP1 coordinates TP53-driven DNA damage responses and suppression of intestinal carcinogenesis. Gastroenterology. PMID 34599932 DOI: 10.1053/j.gastro.2021.09.057  0.146
2021 Gandhi AK, Sun ZJ, Kim WM, Huang YH, Kondo Y, Bonsor DA, Sundberg EJ, Wagner G, Kuchroo VK, Petsko GA, Blumberg RS. Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium. Communications Biology. 4: 360. PMID 33742094 DOI: 10.1038/s42003-021-01871-2  0.14
2012 Tilg H, Blumberg R, Enders S, Kaser A, Manns M. Innate immunity in gastrointestinal disorders: Basic and therapeutic concepts Digestive Diseases. 30: 1. PMID 23075862 DOI: 10.1159/000341113  0.14
2022 Ye H, Chen C, Wu H, Zheng K, Martín-Adrados B, Caparros E, Francés R, Nelson LJ, Gómez Del Moral M, Asensio I, Vaquero J, Bañares R, Ávila MA, Andrade RJ, Isabel Lucena M, ... ... Blumberg RS, et al. Genetic and pharmacological inhibition of XBP1 protects against APAP hepatotoxicity through the activation of autophagy. Cell Death & Disease. 13: 143. PMID 35145060 DOI: 10.1038/s41419-022-04580-8  0.137
2024 Gaudino SJ, Singh A, Huang H, Padiadpu J, Jean-Pierre M, Kempen C, Bahadur T, Shiomitsu K, Blumberg R, Shroyer KR, Beyaz S, Shulzhenko N, Morgun A, Kumar P. Intestinal IL-22RA1 signaling regulates intrinsic and systemic lipid and glucose metabolism to alleviate obesity-associated disorders. Nature Communications. 15: 1597. PMID 38383607 DOI: 10.1038/s41467-024-45568-6  0.136
2022 Exley MA, Gensollen T, Blumberg RS. A nano-engager for iNKT cells in cancer. Nature Cancer. 1: 1032-1034. PMID 35122067 DOI: 10.1038/s43018-020-00138-9  0.132
2009 Nieuwenhuis E, Matsumoto T, Lindenbergh-Kortleve D, Middendorp S, Willemsen R, Kaser A, Simons-Oosterhuis Y, Brugman S, Yamaguchi K, Ishikawa H, Aiba Y, Koga Y, Samsom J, Oshima K, Kikuchi M, ... ... Blumberg R, et al. O01 CD1D-DEPENDENT REGULATION OF BACTERIAL COLONIZATION IN THE INTESTINE Journal of Crohn's and Colitis Supplements. 3: 1. DOI: 10.1016/S1873-9954(09)70002-3  0.128
1987 Blumberg RS, Hartshorn KL, Ardman B, Kaplan JC, Paradis T, Vogt M, Hirsch MS, Schooley RT. Dot immunobinding assay for detection of human immunodeficiency virus-associated antigens. Journal of Clinical Microbiology. 25: 1989-1992. DOI: 10.1128/jcm.25.10.1989-1992.1987  0.127
2016 Grover S, Lim RM, Blumberg RS, Syngal S. Oncogastroenterology. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26834060 DOI: 10.1200/JCO.2015.65.7973  0.12
2023 Armitage CW, O'Meara CP, Bryan ER, Kollipara A, Trim LK, Hickey D, Carey AJ, Huston WM, Donnelly G, Yazdani A, Blumberg RS, Beagley KW. IgG exacerbates genital chlamydial pathology in females by enhancing pathogenic CD8 T cell responses. Scandinavian Journal of Immunology. 99: e13331. PMID 38441219 DOI: 10.1111/sji.13331  0.12
2024 Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, ... ... Blumberg RS, et al. Author Correction: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature. PMID 38336833 DOI: 10.1038/s41586-024-07164-y  0.11
2013 Niederreiter L, Fritz T, Adolph T, Krismer A, Offner F, Hosomi S, Tomczak M, Enrich B, Sarcevic E, Tschurtschenthaler M, Kempster S, Iwawaki T, Kohno K, Tilg H, Blumberg R, et al. 7 ER stress transcription factor Xbp1 suppresses intestinal tumourigenesis Journal of Crohn's and Colitis. 7: S3-S4. DOI: 10.1016/S1873-9946(13)60008-2  0.106
2022 Gandhi AK, Sun ZJ, Huang YH, Kim WM, Yang C, Petsko GA, Beauchemin N, Blumberg RS. Structural analysis of human CEACAM1 oligomerization. Communications Biology. 5: 1042. PMID 36180783 DOI: 10.1038/s42003-022-03996-4  0.1
2010 Zeissig S, Blumberg RS. Host Response to Bacterial Homeostasis Inflammatory Bowel Disease: Translating Basic Science Into Clinical Practice. 92-118. DOI: 10.1002/9781444318418.ch9  0.095
2008 Blumberg RS. Crohn disease. Jama. 300: 439-40. PMID 18647989 DOI: 10.1001/jama.300.4.439  0.082
2022 Oh SF, Praveena T, Song H, Yoo JS, Jung DJ, Erturk-Hasdemir D, Hwang YS, Lee CC, Le Nours J, Kim H, Lee J, Blumberg RS, Rossjohn J, Park SB, Kasper DL. Publisher Correction: Host immunomodulatory lipids created by symbionts from dietary amino acids. Nature. PMID 35001086 DOI: 10.1038/s41586-021-04276-7  0.057
1998 AGUAN K, TAYLOR D, BLUMBERG R, THOMPSON L, EDWARDS D, WEINER C. Effect of acute focal hypoxia on Ca-dependent and independent activity and mRNA expression in the immature rat brain Journal of the Society For Gynecologic Investigation. 5: 163A-163A. DOI: 10.1016/S1071-5576(97)86584-7  0.047
2008 Kugathasan S, Saubermann LJ, Smith L, Kou D, Itoh J, Binion DG, Levine AD, Blumberg RS, Fiocchi C. Authors' reply Gut. 57: 1629.  0.01
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