Athanassios Giannis - Publications

Universität Leipzig, Leipzig, Sachsen, Germany 

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Psarra V, Fousteris MA, Hennig L, Bantzi M, Giannis A, Nikolaropoulos SS. Identification of azepinone fused tetracyclic heterocycles as new chemotypes with protein kinase inhibitory activities Tetrahedron. 72: 2376-2385. DOI: 10.1016/j.tet.2016.03.048  1
2015 Malca Garcia GR, Hennig L, Shelukhina IV, Kudryavtsev DS, Bussmann RW, Tsetlin VI, Giannis A. Curare Alkaloids: Constituents of a Matis Dart Poison. Journal of Natural Products. 78: 2537-44. PMID 26496427 DOI: 10.1021/acs.jnatprod.5b00457  1
2015 Bantzi M, Rigol S, Giannis A. Synthesis of a hexasaccharide partial sequence of hyaluronan for click chemistry and more. Beilstein Journal of Organic Chemistry. 11: 604-7. PMID 26113878 DOI: 10.3762/bjoc.11.67  1
2015 Heretsch P, Giannis A. The Veratrum and Solanum alkaloids. The Alkaloids. Chemistry and Biology. 74: 201-32. PMID 25845062 DOI: 10.1016/bs.alkal.2014.11.002  1
2015 Greifenhagen U, Nguyen VD, Moschner J, Giannis A, Frolov A, Hoffmann R. Sensitive and site-specific identification of carboxymethylated and carboxyethylated peptides in tryptic digests of proteins and human plasma. Journal of Proteome Research. 14: 768-77. PMID 25423611 DOI: 10.1021/pr500799m  1
2015 Magoulas GE, Bantzi M, Messari D, Voulgari E, Gialeli C, Barbouri D, Giannis A, Karamanos NK, Papaioannou D, Avgoustakis K. Synthesis and evaluation of anticancer activity in cells of novel stoichiometric pegylated fullerene-doxorubicin conjugates. Pharmaceutical Research. 32: 1676-93. PMID 25380982 DOI: 10.1007/s11095-014-1566-1  1
2015 Glynos C, Toumpanakis D, Loverdos K, Karavana V, Zhou Z, Magkou C, Dettoraki M, Perlikos F, Pavlidou A, Kotsikoris V, Topouzis S, Theocharis SE, Brouckaert P, Giannis A, Papapetropoulos A, et al. Guanylyl cyclase activation reverses resistive breathing-induced lung injury and inflammation. American Journal of Respiratory Cell and Molecular Biology. 52: 762-71. PMID 25353067 DOI: 10.1165/rcmb.2014-0092OC  1
2015 Smeilus T, Hennig L, Beyer L, Sieler J, Giannis A. The Mistake in Carl Bosch's PhD Thesis: A Contribution to "Retro-Chemistry" Synthesis (Germany). 47: 1887-1892. DOI: 10.1055/s-0034-1380495  1
2015 Thiele M, Rabe S, Hessenkemper W, Roell D, Bartsch S, Kraft F, Abraham TE, Houtsmuller AB, Van Royen ME, Giannis A, Baniahmad A. Novel nor-homo-and spiro-oxetan- steroids target the human androgen receptor and act as antiandrogens Current Medicinal Chemistry. 22: 1156-1167.  1
2014 Wratil PR, Rigol S, Solecka B, Kohla G, Kannicht C, Reutter W, Giannis A, Nguyen LD. A novel approach to decrease sialic acid expression in cells by a C-3-modified N-acetylmannosamine. The Journal of Biological Chemistry. 289: 32056-63. PMID 25278018 DOI: 10.1074/jbc.M114.608398  1
2014 Rabe S, Moschner J, Bantzi M, Heretsch P, Giannis A. C-H-Functionalization logic guides the synthesis of a carbacyclopamine analog. Beilstein Journal of Organic Chemistry. 10: 1564-9. PMID 25161712 DOI: 10.3762/bjoc.10.161  0.44
2014 Qiu S, Mintz JD, Salet CD, Han W, Giannis A, Chen F, Yu Y, Su Y, Fulton DJ, Stepp DW. Increasing muscle mass improves vascular function in obese (db/db) mice. Journal of the American Heart Association. 3: e000854. PMID 24965025 DOI: 10.1161/JAHA.114.000854  1
2014 Barman SA, Chen F, Su Y, Dimitropoulou C, Wang Y, Catravas JD, Han W, Orfi L, Szantai-Kis C, Keri G, Szabadkai I, Barabutis N, Rafikova O, Rafikov R, Black SM, ... ... Giannis A, et al. NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1704-15. PMID 24947524 DOI: 10.1161/ATVBAHA.114.303848  0.44
2014 Chatzopoulou M, Antoniou A, Pitsinos EN, Bantzi M, Koulocheri SD, Haroutounian SA, Giannis A. A fast entry to furanoditerpenoid-based Hedgehog signaling inhibitors: identifying essential structural features. Organic Letters. 16: 3344-7. PMID 24895068 DOI: 10.1021/ol501370j  0.44
2014 Smadbeck J, Peterson MB, Zee BM, Garapaty S, Mago A, Lee C, Giannis A, Trojer P, Garcia BA, Floudas CA. De novo peptide design and experimental validation of histone methyltransferase inhibitors. Plos One. 9: e90095. PMID 24587223 DOI: 10.1371/journal.pone.0090095  1
2014 Chentsova A, Kapourani E, Giannis A. Synthesis of novel derivatives of 5-hydroxymethylcytosine and 5-formylcytosine as tools for epigenetics. Beilstein Journal of Organic Chemistry. 10: 7-11. PMID 24454558 DOI: 10.3762/bjoc.10.2  0.44
2014 Heretsch P, Giannis A. Cyclopamine and Congeners Natural Products in Medicinal Chemistry. 545-564. DOI: 10.1002/9783527676545.ch15  1
2013 Moschner J, Chentsova A, Eilert N, Rovardi I, Heretsch P, Giannis A. Cyclopamine analogs bearing exocyclic methylenes are highly potent and acid-stable inhibitors of hedgehog signaling. Beilstein Journal of Organic Chemistry. 9: 2328-35. PMID 24367396 DOI: 10.3762/bjoc.9.267  0.44
2013 von Wantoch Rekowski M, Kumar V, Zhou Z, Moschner J, Marazioti A, Bantzi M, Spyroulias GA, van den Akker F, Giannis A, Papapetropoulos A. Insights into soluble guanylyl cyclase activation derived from improved heme-mimetics. Journal of Medicinal Chemistry. 56: 8948-52. PMID 24090476 DOI: 10.1021/jm400539d  0.44
2013 Glynos C, Dupont LL, Vassilakopoulos T, Papapetropoulos A, Brouckaert P, Giannis A, Joos GF, Bracke KR, Brusselle GG. The role of soluble Guanylyl Cyclase in chronic obstructive pulmonary disease American Journal of Respiratory and Critical Care Medicine. 188: 789-799. PMID 23841447 DOI: 10.1164/rccm.201210-1884OC  0.44
2013 Kesisova IA, Nakos KC, Tsolou A, Angelis D, Lewis J, Chatzaki A, Agianian B, Giannis A, Koffa MD. Tripolin A, a novel small-molecule inhibitor of aurora A kinase, reveals new regulation of HURP's distribution on microtubules. Plos One. 8: e58485. PMID 23516487 DOI: 10.1371/journal.pone.0058485  1
2013 Asimakopoulou A, Panopoulos P, Chasapis CT, Coletta C, Zhou Z, Cirino G, Giannis A, Szabo C, Spyroulias GA, Papapetropoulos A. Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE). British Journal of Pharmacology. 169: 922-32. PMID 23488457 DOI: 10.1111/bph.12171  0.44
2013 Rigol S, Xia L, Giannis A. Synthesis of ¹³C-labeled and functionalized Hyaluronan derivatives for biophysical studies and surface modifications. Bioorganic & Medicinal Chemistry. 21: 733-41. PMID 23266183 DOI: 10.1016/j.bmc.2012.11.025  0.44
2012 Aurich A, Specht R, Müller RA, Stottmeister U, Yovkova V, Otto C, Holz M, Barth G, Heretsch P, Thomas FA, Sicker D, Giannis A. Microbiologically produced carboxylic acids used as building blocks in organic synthesis. Sub-Cellular Biochemistry. 64: 391-423. PMID 23080261 DOI: 10.1007/978-94-007-5055-5_19  0.44
2012 Seifert K, Büttner A, Rigol S, Eilert N, Wandel E, Giannis A. Potent small molecule Hedgehog agonists induce VEGF expression in vitro. Bioorganic & Medicinal Chemistry. 20: 6465-81. PMID 22985958 DOI: 10.1016/j.bmc.2012.08.026  0.44
2012 Zhou Z, von Wantoch Rekowski M, Coletta C, Szabo C, Bucci M, Cirino G, Topouzis S, Papapetropoulos A, Giannis A. Thioglycine and L-thiovaline: biologically active H₂S-donors. Bioorganic & Medicinal Chemistry. 20: 2675-8. PMID 22436388 DOI: 10.1016/j.bmc.2012.02.028  0.44
2011 Heretsch P, Büttner A, Tzagkaroulaki L, Zahn S, Kirchner B, Giannis A. Exo-cyclopamine--a stable and potent inhibitor of hedgehog-signaling. Chemical Communications (Cambridge, England). 47: 7362-4. PMID 21589966 DOI: 10.1039/c1cc11782c  0.44
2011 Vasconcelos RS, Silva LF, Giannis A. Synthesis of tetrahydrofurans by cyclization of homoallylic alcohols with iodine/iodine(III). The Journal of Organic Chemistry. 76: 1499-502. PMID 21244003 DOI: 10.1021/jo102413u  0.44
2011 Hennig L, Garcia GM, Giannis A, Bussmann RW. New constituents of Baccharis genistelloides (Lam.) Pers Arkivoc. 2011: 74-81.  0.44
2010 Lüke J, Nassar K, Lüke M, Tura A, Merz H, Giannis A, Grisanti S. The effect of adjuvant dimethylenastron, a mitotic Kinesin Eg5 inhibitor, in experimental glaucoma filtration surgery. Current Eye Research. 35: 1090-8. PMID 20961218 DOI: 10.3109/02713683.2010.512408  0.44
2010 Fousteris MA, Schubert U, Roell D, Roediger J, Bailis N, Nikolaropoulos SS, Baniahmad A, Giannis A. 20-Aminosteroids as a novel class of selective and complete androgen receptor antagonists and inhibitors of prostate cancer cell growth. Bioorganic & Medicinal Chemistry. 18: 6960-9. PMID 20826091 DOI: 10.1016/j.bmc.2010.08.029  0.44
2010 Heretsch P, Tzagkaroulaki L, Giannis A. Modulators of the hedgehog signaling pathway. Bioorganic & Medicinal Chemistry. 18: 6613-24. PMID 20708941 DOI: 10.1016/j.bmc.2010.07.038  0.44
2010 Heretsch P, Rabe S, Giannis A. A biomimetic approach to C-nor-D-homo-steroids. Journal of the American Chemical Society. 132: 9968-9. PMID 20597501 DOI: 10.1021/ja103152k  0.44
2010 Blasco MA, Thumann S, Wittmann J, Giannis A, Gröger H. Enantioselective biocatalytic synthesis of (S)-monastrol. Bioorganic & Medicinal Chemistry Letters. 20: 4679-82. PMID 20566290 DOI: 10.1016/j.bmcl.2010.05.063  0.44
2010 Rekowski Mv, Giannis A. Histone acetylation modulation by small molecules: a chemical approach. Biochimica Et Biophysica Acta. 1799: 760-7. PMID 20493978 DOI: 10.1016/j.bbagrm.2010.05.006  0.44
2010 Büttner A, Cottin T, Xu J, Tzagkaroulaki L, Giannis A. Serotonin derivatives as a new class of non-ATP-competitive receptor tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry. 18: 3387-402. PMID 20456957 DOI: 10.1016/j.bmc.2010.04.001  0.44
2010 Heretsch P, Tzagkaroulaki L, Giannis A. Cyclopamine and hedgehog signaling: chemistry, biology, medical perspectives. Angewandte Chemie (International Ed. in English). 49: 3418-27. PMID 20429080 DOI: 10.1002/anie.200906967  0.44
2010 Churruca F, Fousteris M, Ishikawa Y, Rekowski Mv, Hounsou C, Surrey T, Giannis A. A novel approach to indoloditerpenes by Nazarov photocyclization: synthesis and biological investigations of terpendole E analogues. Organic Letters. 12: 2096-9. PMID 20387880 DOI: 10.1021/ol100579w  0.44
2010 von Wantoch Rekowski M, Pyriochou A, Papapetropoulos N, Stössel A, Papapetropoulos A, Giannis A. Synthesis and biological evaluation of oxadiazole derivatives as inhibitors of soluble guanylyl cyclase. Bioorganic & Medicinal Chemistry. 18: 1288-96. PMID 20036129 DOI: 10.1016/j.bmc.2009.12.027  0.44
2010 Morbidelli L, Pyriochou A, Filippi S, Vasileiadis I, Roussos C, Zhou Z, Loutrari H, Waltenberger J, Stössel A, Giannis A, Ziche M, Papapetropoulos A. The soluble guanylyl cyclase inhibitor NS-2028 reduces vascular endothelial growth factor-induced angiogenesis and permeability. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 298: R824-32. PMID 20032260 DOI: 10.1152/ajpregu.00222.2009  0.44
2009 Heretsch P, Rabe S, Giannis A. Synthesis of all diastereomers of the piperidine--alkaloid substructure of cyclopamine. Organic Letters. 11: 5410-2. PMID 19883099 DOI: 10.1021/ol902270f  0.44
2009 Giannis A, Heretsch P, Sarli V, Stössel A. Synthesis of cyclopamine using a biomimetic and diastereoselective approach. Angewandte Chemie (International Ed. in English). 48: 7911-4. PMID 19591183 DOI: 10.1002/anie.200902520  1
2009 Büttner A, Seifert K, Cottin T, Sarli V, Tzagkaroulaki L, Scholz S, Giannis A. Synthesis and biological evaluation of SANT-2 and analogues as inhibitors of the hedgehog signaling pathway. Bioorganic & Medicinal Chemistry. 17: 4943-54. PMID 19541490 DOI: 10.1016/j.bmc.2009.06.008  0.44
2009 Rothley M, Schmid A, Thiele W, Schacht V, Plaumann D, Gartner M, Yektaoglu A, Bruyère F, Noël A, Giannis A, Sleeman JP. Hyperforin and aristoforin inhibit lymphatic endothelial cell proliferation in vitro and suppress tumor-induced lymphangiogenesis in vivo. International Journal of Cancer. Journal International Du Cancer. 125: 34-42. PMID 19326439 DOI: 10.1002/ijc.24295  1
2009 Sardon T, Cottin T, Xu J, Giannis A, Vernos I. Development and biological evaluation of a novel aurora A kinase inhibitor. Chembiochem : a European Journal of Chemical Biology. 10: 464-78. PMID 19199284 DOI: 10.1002/cbic.200800600  1
2008 Sarli V, Giannis A. Targeting the kinesin spindle protein: basic principles and clinical implications. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 7583-7. PMID 19047082 DOI: 10.1158/1078-0432.CCR-08-0120  1
2008 Dietz A, Boehm A, Mozet C, Wichmann G, Giannis A. Current aspects of targeted therapy in head and neck tumors. European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (Eufos) : Affiliated With the German Society For Oto-Rhino-Laryngology - Head and Neck Surgery. 265: S3-12. PMID 18535834 DOI: 10.1007/s00405-008-0697-6  1
2008 Heretsch P, Thomas F, Aurich A, Krautscheid H, Sicker D, Giannis A. Syntheses with a chiral building block from the citric acid cycle: (2R,3S)-isocitric acid by fermentation of sunflower oil. Angewandte Chemie (International Ed. in English). 47: 1958-60. PMID 18236482 DOI: 10.1002/anie.200705000  1
2008 Baumann F, Mauz-Körholz C, Clauss D, Borrmann S, Giannis A, Merkel N, Körholz D, Preiss R. Determination of terephthalic acid isopropylamide in urine with a liquid chromatography/mass spectrometry (LC/MS) method. Journal of Clinical Laboratory Analysis. 22: 21-8. PMID 18200575 DOI: 10.1002/jcla.20213  1
2008 Wehner F, Nören-Müller A, Müller O, Reis-Corrêa I, Giannis A, Waldmann H. Indoloquinolizidine derivatives as novel and potent apoptosis inducers and cell-cycle blockers. Chembiochem : a European Journal of Chemical Biology. 9: 401-5. PMID 18189263 DOI: 10.1002/cbic.200700558  1
2008 Tsanakopoulou M, Cottin T, Büttner A, Sarli V, Malamidou-Xenikaki E, Spyroudis S, Giannis A. Indeno[1,2-d]pyrido[1,2-a]pyrimidines: a new class of receptor tyrosine kinase inhibitors. Chemmedchem. 3: 429-33. PMID 18181120 DOI: 10.1002/cmdc.200700306  1
2008 Mann S, Sarli V, Giannis A. A convenient synthesis of functionalized furans Synthesis. 2617-2625. DOI: 10.1055/s-2008-1067183  1
2008 Giannis A. Peptidomimetics: Modern approaches and medical perspectives Organic Synthesis Highlights Iii. 354-365. DOI: 10.1002/9783527619962.ch52  1
2008 Giannis A. Analogues of the sialyl lewisx group and of the N-Acetylneuraminic acid in the antiadhesion therapy Organic Synthesis Highlights Iii. 342-353. DOI: 10.1002/9783527619962.ch51  1
2008 Giannis A. White biotechnology for greener chemistry Manufacturing Chemist. 79: 25-26.  1
2008 Giannis A. Isocitric acid from sunflower oil fermentation Industrial Bioprocessing. 30: 9.  1
2007 Pyriochou A, Tsigkos S, Vassilakopoulos T, Cottin T, Zhou Z, Gourzoulidou E, Roussos C, Waldmann H, Giannis A, Papapetropoulos A. Anti-angiogenic properties of a sulindac analogue. British Journal of Pharmacology. 152: 1207-14. PMID 17965739 DOI: 10.1038/sj.bjp.0707534  1
2007 Batova A, Lam T, Wascholowski V, Yu AL, Giannis A, Theodorakis EA. Synthesis and evaluation of caged Garcinia xanthones. Organic & Biomolecular Chemistry. 5: 494-500. PMID 17252132 DOI: 10.1039/b612903j  1
2007 Müller C, Gross D, Sarli V, Gartner M, Giannis A, Bernhardt G, Buschauer A. Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells. Cancer Chemotherapy and Pharmacology. 59: 157-64. PMID 16703323 DOI: 10.1007/s00280-006-0254-1  1
2007 Heretsch P, Giannis A. An efficient entry to amino-substituted resorcylic acid derivatives for the synthesis of platensimycin and analogues Synthesis. 2614-2616. DOI: 10.1055/s-2007-983843  1
2006 Wascholowski V, Giannis A, Pitsinos EN. Influence of the scyphostatin side chain on the mode of inhibition of neutral sphingomyelinase. Chemmedchem. 1: 718-21. PMID 16902925 DOI: 10.1002/cmdc.200600099  1
2006 Sarli V, Giannis A. Inhibitors of mitotic kinesins: next-generation antimitotics. Chemmedchem. 1: 293-8. PMID 16892362 DOI: 10.1002/cmdc.200500045  1
2006 Thiele CM, Marx A, Berger R, Fischer J, Biel M, Giannis A. Determination of the relative configuration of a five-membered lactone from residual dipolar couplings. Angewandte Chemie (International Ed. in English). 45: 4455-60. PMID 16763954 DOI: 10.1002/anie.200503247  1
2006 Liu M, Aneja R, Liu C, Sun L, Gao J, Wang H, Dong JT, Sarli V, Giannis A, Joshi HC, Zhou J. Inhibition of the mitotic kinesin Eg5 up-regulates Hsp70 through the phosphatidylinositol 3-kinase/Akt pathway in multiple myeloma cells. The Journal of Biological Chemistry. 281: 18090-7. PMID 16627469 DOI: 10.1074/jbc.M601324200  1
2006 Biel M, Deck P, Giannis A, Waldmann H. Synthesis and evaluation of acyl protein thioesterase 1 (APT1) inhibitors. Chemistry (Weinheim An Der Bergstrasse, Germany). 12: 4121-43. PMID 16528788 DOI: 10.1002/chem.200501128  1
2006 Wascholowski V, Giannis A. Sphingolactones: selective and irreversible inhibitors of neutral sphingomyelinase. Angewandte Chemie (International Ed. in English). 45: 827-30. PMID 16365835 DOI: 10.1002/anie.200501983  1
2006 Schulze A, Pagona G, Giannis A. Oxone/sodium chloride: A simple and efficient catalytic system for the oxidation of alcohols to symmetric esters and ketones Synthetic Communications. 36: 1147-1156. DOI: 10.1080/00397910500514030  1
2006 Schulze A, Giannis A. Oxidation of alcohols with catalytic amounts of IBX Synthesis. 257-260. DOI: 10.1055/s-2005-924764  1
2005 Sarli V, Huemmer S, Sunder-Plassmann N, Mayer TU, Giannis A. Synthesis and biological evaluation of novel EG5 inhibitors. Chembiochem : a European Journal of Chemical Biology. 6: 2005-13. PMID 16216042 DOI: 10.1002/cbic.200500168  1
2005 Hoffmann J, Feng Y, vom Hagen F, Hillenbrand A, Lin J, Erber R, Vajkoczy P, Gourzoulidou E, Waldmann H, Giannis A, Wolburg H, Shani M, Jaeger V, Weich HA, Preissner KT, et al. Endothelial survival factors and spatial completion, but not pericyte coverage of retinal capillaries determine vessel plasticity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 2035-6. PMID 16215210 DOI: 10.1096/fj.04-2109fje  1
2005 Sunder-Plassmann N, Sarli V, Gartner M, Utz M, Seiler J, Huemmer S, Mayer TU, Surrey T, Giannis A. Synthesis and biological evaluation of new tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin Eg5. Bioorganic & Medicinal Chemistry. 13: 6094-111. PMID 16084101 DOI: 10.1016/j.bmc.2005.06.027  1
2005 Deck P, Pendzialek D, Biel M, Wagner M, Popkirova B, Ludolph B, Kragol G, Kuhlmann J, Giannis A, Waldmann H. Development and biological evaluation of acyl protein thioesterase 1 (APT1) inhibitors. Angewandte Chemie (International Ed. in English). 44: 4975-80. PMID 16003812 DOI: 10.1002/anie.200462625  1
2005 Mazitschek R, Huwe A, Giannis A. Synthesis and biological evaluation of novel fumagillin and ovalicin analogues. Organic & Biomolecular Chemistry. 3: 2150-4. PMID 15917904 DOI: 10.1039/b503163j  1
2005 Gartner M, Sunder-Plassmann N, Seiler J, Utz M, Vernos I, Surrey T, Giannis A. Development and biological evaluation of potent and specific inhibitors of mitotic Kinesin Eg5. Chembiochem : a European Journal of Chemical Biology. 6: 1173-7. PMID 15912555 DOI: 10.1002/cbic.200500005  1
2005 Biel M, Wascholowski V, Giannis A. Epigenetics--an epicenter of gene regulation: histones and histone-modifying enzymes. Angewandte Chemie (International Ed. in English). 44: 3186-216. PMID 15898057 DOI: 10.1002/anie.200461346  1
2005 Gourzoulidou E, Carpintero M, Baumhof P, Giannis A, Waldmann H. Inhibition of angiogenesis-relevant receptor tyrosine kinases by sulindac analogues. Chembiochem : a European Journal of Chemical Biology. 6: 527-31. PMID 15696596 DOI: 10.1002/cbic.200400192  1
2005 Anderluh M, Cesar J, Stefanic P, Kikelj D, Janes D, Murn J, Nadrah K, Tominc M, Addicks E, Giannis A, Stegnar M, Dolenc MS. Design and synthesis of novel platelet fibrinogen receptor antagonists with 2H-1,4-benzoxazine-3(4H)-one scaffold. A systematic study. European Journal of Medicinal Chemistry. 40: 25-49. PMID 15642407 DOI: 10.1016/j.ejmech.2004.09.004  1
2005 Gartner M, Müller T, Simon JC, Giannis A, Sleeman JP. Aristoforin, a novel stable derivative of hyperforin, is a potent anticancer agent. Chembiochem : a European Journal of Chemical Biology. 6: 171-7. PMID 15593112 DOI: 10.1002/cbic.200400195  1
2004 Biel M, Wascholowski V, Giannis A. A fatal affair: the ubiquitinylation of proteins. Angewandte Chemie (International Ed. in English). 43: 6414-6. PMID 15578782 DOI: 10.1002/anie.200462346  1
2004 Sunder-Plassmann N, Giannis A. Novel activators of the tumour suppressor p53. Chembiochem : a European Journal of Chemical Biology. 5: 1635-7. PMID 15526327 DOI: 10.1002/cbic.200400194  1
2004 Kirkin V, Thiele W, Baumann P, Mazitschek R, Rohde K, Fellbrich G, Weich H, Waltenberger J, Giannis A, Sleeman JP. MAZ51, an indolinone that inhibits endothelial cell and tumor cell growth in vitro, suppresses tumor growth in vivo. International Journal of Cancer. Journal International Du Cancer. 112: 986-93. PMID 15386354 DOI: 10.1002/ijc.20509  1
2004 Al-Rawi S, Hinderlich S, Reutter W, Giannis A. Synthesis and biochemical properties of reversible inhibitors of UDP-N-acetylglucosamine 2-epimerase. Angewandte Chemie (International Ed. in English). 43: 4366-70. PMID 15368395 DOI: 10.1002/anie.200453863  1
2004 Gey C, Giannis A. Small molecules, big plans--can low-molecular-weight compounds control human regeneration? Angewandte Chemie (International Ed. in English). 43: 3998-4000. PMID 15300685 DOI: 10.1002/anie.200460346  1
2004 Mazitschek R, Giannis A. Inhibitors of angiogenesis and cancer-related receptor tyrosine kinases. Current Opinion in Chemical Biology. 8: 432-41. PMID 15288254 DOI: 10.1016/j.cbpa.2004.06.009  1
2004 Biel M, Kretsovali A, Karatzali E, Papamatheakis J, Giannis A. Design, synthesis, and biological evaluation of a small-molecule inhibitor of the histone acetyltransferase Gcn5. Angewandte Chemie (International Ed. in English). 43: 3974-6. PMID 15274229 DOI: 10.1002/anie.200453879  1
2004 Unsoeld AS, Junker B, Mazitschek R, Martin G, Hansen LL, Giannis A, Agostini HT. Local injection of receptor tyrosine kinase inhibitor MAE 87 reduces retinal neovascularization in mice. Molecular Vision. 10: 468-75. PMID 15273654  1
2004 Stefanic P, Simoncic Z, Breznik M, Plavec J, Anderluh M, Addicks E, Giannis A, Kikelj D. Conformationally tailored N-[(2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl)carbonyl]proline templates as molecular tools for the design of peptidomimetics. Design and synthesis of fibrinogen receptor antagonists. Organic & Biomolecular Chemistry. 2: 1511-7. PMID 15136808 DOI: 10.1039/b400490f  1
2004 Rosenbaum C, Baumhof P, Mazitschek R, Müller O, Giannis A, Waldmann H. Synthesis and biological evaluation of an indomethacin library reveals a new class of angiogenesis-related kinase inhibitors. Angewandte Chemie (International Ed. in English). 43: 224-8. PMID 14695616 DOI: 10.1002/anie.200352582  1
2004 Schulze A, Giannis A. IBX-mediated conversion of primary alcohols and aldehydes to N-hydroxysuccinimide esters Advanced Synthesis and Catalysis. 346: 252-256.  1
2003 Pitsinos EN, Wascholowski V, Karaliota S, Rigou C, Couladouros EA, Giannis A. Synthesis and evaluation of three novel scyphostatin analogues as neutral sphingomyelinase inhibitors. Chembiochem : a European Journal of Chemical Biology. 4: 1223-5. PMID 14613115 DOI: 10.1002/cbic.200300667  1
2003 Stieber F, Grether U, Mazitschek R, Soric N, Giannis A, Waldmann H. Multistep solid-phase synthesis of an antibiotic and receptor tyrosine kinase inhibitors using the traceless phenylhydrazide linker. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 3282-91. PMID 12866072 DOI: 10.1002/chem.200304821  1
2003 Kissau L, Stahl P, Mazitschek R, Giannis A, Waldmann H. Development of natural product-derived receptor tyrosine kinase inhibitors based on conservation of protein domain fold. Journal of Medicinal Chemistry. 46: 2917-31. PMID 12825933 DOI: 10.1021/jm0307943  1
2003 Huwe A, Mazitschek R, Giannis A. Small molecules as inhibitors of cyclin-dependent kinases. Angewandte Chemie (International Ed. in English). 42: 2122-38. PMID 12761741 DOI: 10.1002/anie.200200540  1
2003 Mülbaier M, Giannis A. First synthesis and oxidative properties of polymer-supported IBX Arkivoc. 2003: 228-236.  1
2003 Addicks E, Giannis A. Angiogenesis inhibitors for antitumor therapy | Angiogenese-inhibitoren für die antitumor-therapie Nachrichten Aus Der Chemie. 51: 136-141.  1
2002 Stahl P, Kissau L, Mazitschek R, Giannis A, Waldmann H. Natural product derived receptor tyrosine kinase inhibitors: identification of IGF1R, Tie-2, and VEGFR-3 inhibitors. Angewandte Chemie (International Ed. in English). 41: 1174-8. PMID 12491250 DOI: 10.1002/1521-3773(20020402)41:7<1174::AID-ANIE1174>3.0.CO;2-V  1
2002 Stieber F, Mazitschek R, Soric N, Giannis A, Waldmann H. Traceless solid-phase synthesis of 2-aminothiazoles: receptor tyrosine kinase inhibitors with dual selectivity for Tie-2 and VEGFR-2. Angewandte Chemie (International Ed. in English). 41: 4757-61. PMID 12481350 DOI: 10.1002/anie.200290040  1
2002 Mazitschek R, Mülbaier M, Giannis A. IBX-mediated oxidation of primary alcohols and aldehydes to form carboxylic acids. Angewandte Chemie (International Ed. in English). 41: 4059-61. PMID 12412081 DOI: 10.1002/1521-3773(20021104)41:21<4059::AID-ANIE4059>3.0.CO;2-R  1
2002 Addicks E, Mazitschek R, Giannis A. Synthesis and biological investigation of novel tricyclic benzodiazepinedione-based RGD analogues. Chembiochem : a European Journal of Chemical Biology. 3: 1078-88. PMID 12404633 DOI: 10.1002/1439-7633(20021104)3:11<1078::AID-CBIC1078>3.0.CO;2-2  1
2002 Mazitschek R, Baumhof P, Giannis A. Peptidomimetics and angiogenesis. Mini Reviews in Medicinal Chemistry. 2: 491-506. PMID 12370049  1
2001 Wascholowski V, Giannis A. Neutral sphingomyelinase as a target for drug design. Drug News & Perspectives. 14: 581-90. PMID 12806424  1
2001 Mülbaier M, Giannis A. The Synthesis and Oxidative Properties of Polymer-Supported IBX. Angewandte Chemie (International Ed. in English). 40: 4393-4394. PMID 12404425 DOI: 10.1002/1521-3773(20011203)40:23<4393::AID-ANIE4393>3.0.CO;2-2  1
2001 Stahl P, Kissau L, Mazitschek R, Huwe A, Furet P, Giannis A, Waldmann H. Total synthesis and biological evaluation of the nakijiquinones. Journal of the American Chemical Society. 123: 11586-93. PMID 11716712 DOI: 10.1021/ja011413i  1
2001 Kirkin V, Mazitschek R, Krishnan J, Steffen A, Waltenberger J, Pepper MS, Giannis A, Sleeman JP. Characterization of indolinones which preferentially inhibit VEGF-C- and VEGF-D-induced activation of VEGFR-3 rather than VEGFR-2. European Journal of Biochemistry / Febs. 268: 5530-40. PMID 11683876 DOI: 10.1046/j.0014-2956.2001.02476.x  1
2001 Arenz C, Gartner M, Wascholowski V, Giannis A. Synthesis and biochemical investigation of scyphostatin analogues as inhibitors of neutral sphingomyelinase Bioorganic and Medicinal Chemistry. 9: 2901-2904. PMID 11597471 DOI: 10.1016/S0968-0896(01)00165-1  1
2001 Baumhof P, Mazitschek R, Giannis A. A Mild and Effective Method for the Transesterification of Carboxylic Acid Esters P.B. and R.M. are grateful to the Land Baden-Württemberg for a scholarship from the Landesgraduiertenförderung. Angewandte Chemie (International Ed. in English). 40: 3672-3674. PMID 11592218 DOI: 10.1002/1521-3773(20011001)40:19<3672::AID-ANIE3672>3.0.CO;2-Y  1
2001 Ficht S, Mülbaier M, Giannis A. Development of new and efficient polymer-supported hypervalent iodine reagents Tetrahedron. 57: 4863-4866. DOI: 10.1016/S0040-4020(01)00424-0  1
2001 Arenz C, Giannis A. Synthesis of the first selective irreversible inhibitor of neutral sphingomyelinase European Journal of Organic Chemistry. 137-140. DOI: 10.1002/(SICI)1521-3773(20000417)39:8<1440::AID-ANIE1440>3.0.CO;2-R  1
2000 Giannis A. β-Catenin, cyclins, and more: New insights into the pathogenesis, treatment, and prevention of colon cancer Angewandte Chemie - International Edition. 39: 2261-2263. DOI: 10.1002/1521-3773(20000703)39:13<2261::AID-ANIE2261>3.0.CO;2-6  1
2000 Rübsam F, Mazitschek R, Giannis A. Synthesis of chiral piperazinones as versatile scaffolds for peptidomimetics Tetrahedron. 56: 8481-8487.  1
1999 Wernert N, Stanjek A, Hügel A, Giannis A. Inhibition of angiogenesis on the chicken chorioallantoic membrane by Ets 1 antisense oligodeoxyribonucleotides | Hemmung der Angiogenese auf der Chorioallantoismembran des Hühnchens durch Ets 1 Antisenseoligodesoxynukleotide Verhandlungen Der Deutschen Gesellschaft FüR Pathologie. 83: 212-215. PMID 10714212  1
1999 Wernert N, Stanjek A, Kiriakidis S, Hügel A, Jha HC, Mazitschek R, Giannis A. Inhibition of Angiogenesis In Vivo by ets-1 Antisense Oligonucleotides-Inhibition of Ets-1 Transcription Factor Expression by the Antibiotic Fumagillin. Angewandte Chemie (International Ed. in English). 38: 3228-3231. PMID 10556911 DOI: 10.1002/(SICI)1521-3773(19991102)38:21<3228::AID-ANIE3228>3.0.CO;2-8  1
1999 Schröder PN, Giannis A. From substrate to transition state analogues: The first potent inhibitor of sialyltransferases Angewandte Chemie - International Edition. 38: 1379-1380. DOI: 10.1002/(SICI)1521-3773(19990517)38:10<1379::AID-ANIE1379>3.0.CO;2-M  1
1998 Van Echten-Deckert G, Giannis A, Schwarz A, Futerman AH, Sandhoff K. 1-Methylthiodihydroceramide, a novel analog of dihydroceramide, stimulates sphinganine degradation resulting in decreased de novo sphingolipid biosynthesis Journal of Biological Chemistry. 273: 1184-1191. PMID 9422785 DOI: 10.1074/jbc.273.2.1184  1
1997 Rübsam F, Seck S, Giannis A. Barbier-type allylation of chiral α-Aminoaldehydes: Dependence of the stereochemical outcome on metal and allylic halide Tetrahedron. 53: 2823-2834. DOI: 10.1016/S0040-4020(97)00050-1  1
1997 Rübsam F, Evers AM, Michel C, Giannis A. Z-Selective olefination of base-sensitive chiral β-hydroxy-α-aminoaldehydes using a modified Horner-Wadsworth-Emmons reaction Tetrahedron. 53: 1707-1714. DOI: 10.1016/S0040-4020(96)01091-5  1
1997 Giannis A, Rübsam F. Integrin Antagonists and Other Low Molecular Weight Compounds as Inhibitors of Angiogenesis: New Drugs in Cancer Therapy Angewandte Chemie (International Edition in English). 36: 588-590.  1
1997 Giannis A, Rubsam F. Peptidomimetics in drug design Advances in Drug Research. 29: 1-78.  1
1996 Schick A, Kolter T, Giannis A, Sandhoff K. Synthesis of phosphoramide analogues of sphinganine-1-phosphate Tetrahedron. 52: 2945-2956. DOI: 10.1016/0040-4020(95)01119-6  1
1996 Kolter T, Rübsam F, Giannis A, Nieger M. 4-tert-butyloxycarbonyl-6(S)-(hydroxymethyl)-3(S)-(1-methylethyl)piperazin- 2-one Acta Crystallographica Section C: Crystal Structure Communications. 52: 978-980.  1
1995 Schick A, Kolter T, Giannis A, Sandhoff K. Synthesis of phosphonate analogues of sphinganine-1-phosphate and sphingosine-1-phosphate Tetrahedron. 51: 11207-11218. DOI: 10.1016/0040-4020(95)00688-5  1
1994 Giannis A. The sialyl Lewisx group and its analogues as ligands for selectins: Chemoenzymatic syntheses and biological functions Angewandte Chemie (International Edition in English). 33: 178-180.  1
1993 Liessem B, Giannis A, Sandhoff K, Nieger M. Synthese von 2-acetamido-1,4-imino-1,2,4-tridesoxy-d- galaktitol und kompetitive Inhibition der humanen lysosomalen β-hexosaminidase A Carbohydrate Research. 250: 19-30. PMID 8143290 DOI: 10.1016/0008-6215(93)84151-U  1
1993 Giannis A, Kolter T. Peptidomimetics for receptor ligands - Discovery, development, and medical perspectives Angewandte Chemie (International Edition in English). 32: 1244-1267.  1
1992 Zeitler R, Giannis A, Danneschewski S, Henk E, Henk T, Bauer C, Reutter W, Sandhoff K. Inhibition of N-acetylglucosamine kinase and N-acetylmannosamine kinase by 3-O-methyl-N-acetyl-D-glucosamine in vitro European Journal of Biochemistry. 204: 1165-1168. PMID 1312935  1
1992 Brenner-Weiß G, Giannis A, Sandhoff K. Synthesis of potential inhibitors of the glycosphingolipid biosynthesis Tetrahedron. 48: 5855-5860. DOI: 10.1016/S0040-4020(01)90177-2  1
1992 Kolter T, Klein A, Giannis A. Configuratively stable dipeptide aldehydes from D-glucosamine hydrochloride Angewandte Chemie (International Edition in English). 31: 1391-1392.  1
1990 Giannis A, Henk T. Chirospecific synthesis of amino acids, amino aldehydes and amino alcohols from D-glucosamine hydrochloride. A multigram synthesis of N-boc-L-serinal Tetrahedron Letters. 31: 1253-1256. DOI: 10.1016/S0040-4039(00)88778-X  1
1988 Giannis A, Münster P, Sandhoff K, Steglich W. Fragmentation and wittig olefination of glucosamine derivatives-a simple route to open chain amino sugars and chiral glycerols Tetrahedron. 44: 7177-7180. DOI: 10.1016/S0040-4020(01)86086-5  1
1987 Giannis A, Sandhoff K. Diastereoselektive synthese von funktionalisierten C-α- und -β-glykosylderivaten der 2-acetamido-2-desoxy-d-glucose Carbohydrate Research. 171: 201-210. DOI: 10.1016/S0008-6215(00)90887-5  1
1985 Giannis A, Sandhoff K. Stereoselective synthesis of α- C-allyl-glycopyranosides Tetrahedron Letters. 26: 1479-1482. DOI: 10.1016/S0040-4039(00)98529-0  1
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