Michael A. Simmonds - Publications

Affiliations: 
School of Pharmacy, University of London, London, England, United Kingdom 

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2001 Sooksawate T, Simmonds MA. Influence of membrane cholesterol on modulation of the GABA(A) receptor by neuroactive steroids and other potentiators. British Journal of Pharmacology. 134: 1303-11. PMID 11704651 DOI: 10.1038/sj.bjp.0704360  0.461
2001 Sooksawate T, Simmonds MA. Effects of membrane cholesterol on the sensitivity of the GABA(A) receptor to GABA in acutely dissociated rat hippocampal neurones. Neuropharmacology. 40: 178-84. PMID 11114396 DOI: 10.1016/S0028-3908(00)00159-3  0.502
1999 Sooksawate T, Simmonds MA. Effect of membrane cholesterol on the potentiation of GABA A currents by propofol in acutely dissociated rat hippocampal neurones Journal of Pharmacy and Pharmacology. 51: 159.  0.378
1998 Sooksawate T, Simmonds MA. Increased membrane cholesterol reduces the potentiation of GABA(A) currents by neurosteroids in dissociated hippocampal neurones. Neuropharmacology. 37: 1103-10. PMID 9833640 DOI: 10.1016/S0028-3908(98)00113-0  0.537
1998 Sooksawate T, Simmonds MA. Effect of membrane cholesterol enrichment on the potentiation of GABA A currents by neurosteroids Journal of Pharmacy and Pharmacology. 50: 213. DOI: 10.1111/j.2042-7158.1998.tb02413.x  0.494
1997 Zhong Y, Simmonds MA. Interactions between loreclezole, chlormethiazole and pentobarbitone at GABA(A) receptors: functional and binding studies. British Journal of Pharmacology. 121: 1392-6. PMID 9257919 DOI: 10.1038/sj.bjp.0701269  0.615
1996 Zhong Y, Simmonds MA. Pharmacological characterisation of multiple components in the enhancement by pregnanolone and propofol of [3H]flunitrazepam binding to GABAA receptors. Neuropharmacology. 35: 1193-8. PMID 9014134 DOI: 10.1016/S0028-3908(96)00056-1  0.543
1996 Bennett PJ, Simmonds MA. The influence of membrane cholesterol on the GABAA receptor. British Journal of Pharmacology. 117: 87-92. PMID 8825347 DOI: 10.1111/J.1476-5381.1996.Tb15158.X  0.304
1993 Prince RJ, Simmonds MA. Differential antagonism by epipregnanolone of alphaxalone and pregnanolone potentiation of [3H]flunitrazepam binding suggests more than one class of binding site for steroids at GABAA receptors. Neuropharmacology. 32: 59-63. PMID 8381526 DOI: 10.1016/0028-3908(93)90130-U  0.658
1992 Prince RJ, Simmonds MA. Propofol potentiates the binding of [3H]flunitrazepam to the GABAA receptor complex. Brain Research. 596: 238-42. PMID 1334778 DOI: 10.1016/0006-8993(92)91553-Q  0.673
1992 Prince RJ, Simmonds MA. Temperature and anion dependence of allosteric interactions at the gamma-aminobutyric acid-benzodiazepine receptor. Biochemical Pharmacology. 44: 1297-302. PMID 1329765 DOI: 10.1016/0006-2952(92)90529-R  0.661
1992 Prince RJ, Simmonds MA. Steroid modulation of the strychnine-sensitive glycine receptor. Neuropharmacology. 31: 201-5. PMID 1321356 DOI: 10.1016/0028-3908(92)90168-O  0.698
1992 Prince RJ, Simmonds MA. 5 beta-pregnan-3 beta-ol-20-one, a specific antagonist at the neurosteroid site of the GABAA receptor-complex. Neuroscience Letters. 135: 273-5. PMID 1320747 DOI: 10.1016/0304-3940(92)90454-F  0.7
1991 Simmonds MA. Modulation of the GABAA receptor by steroids Seminars in Neuroscience. 3: 231-239. DOI: 10.1016/1044-5765(91)90020-O  0.554
1990 Simmonds MA, Blagbrough IS, Bycroft BW, Mather AJ, Millington S, Smith TW, Usherwood PNR. Mono-acylated spermines: Antagonists of glutamate receptors Journal of Pharmacy and Pharmacology, Supplement. 42: 169P. DOI: 10.1016/0014-2999(90)93364-V  0.353
1990 Simmonds MA, Pettey CJ. Distinction between steroid-induced densensitization to GABA and picrotoxin-like antagonism on cultured cerebral cortical neurones European Journal of Pharmacology. 183: 462-463. DOI: 10.1016/0014-2999(90)93352-Q  0.382
1989 Healing C, Hilton T, Simmonds M. Alphaxolone reveals GABA(A) receptor-mediated inhibition in guinea-pig ileum Journal of Pharmacy and Pharmacology. 41: 410-411. PMID 2570838 DOI: 10.1111/J.2042-7158.1989.Tb06488.X  0.517
1989 Andres-Trelles F, Bibby V, Lustman S, Simmonds MA. Effects of cortisol on GABAA receptor-mediated responses compared in guinea-pig ileum and rat cuneate nucleus. Neuropharmacology. 28: 705-8. PMID 2548112 DOI: 10.1016/0028-3908(89)90154-8  0.471
1989 Turner JP, Simmonds MA. Modulation of the GABAA receptor complex by steroids in slices of rat cuneate nucleus. British Journal of Pharmacology. 96: 409-17. PMID 2538192 DOI: 10.1111/J.1476-5381.1989.Tb11832.X  0.389
1987 Lindgren S, Simmonds MA. Adaptation of the GABAA-receptor complex in rat brain during chronic elevation of GABA by ethanolamine O-sulphate. British Journal of Pharmacology. 91: 617-25. PMID 3038247  0.482
1987 Simmonds MA, Turner JP. Potentiators of responses to activation of gamma-aminobutyric acid (GABAA) receptors. Neuropharmacology. 26: 923-30. PMID 2821435 DOI: 10.1016/0028-3908(87)90071-2  0.538
1986 Horne AL, Harrison NL, Turner JP, Simmonds MA. Spontaneous paroxysmal activity induced by zero magnesium and bicuculline: suppression by NMDA antagonists and GABA mimetics. European Journal of Pharmacology. 122: 231-8. PMID 3519245 DOI: 10.1016/0014-2999(86)90107-X  0.73
1986 Simmonds MA. Classification of inhibitory amino acid receptors in the mammalian nervous system. Medical Biology. 64: 301-11. PMID 3029518  0.524
1985 Simmonds MA, Turner JP. Antagonism of inhibitory amino acids by the steroid derivative RU5135. British Journal of Pharmacology. 84: 631-5. PMID 3986429  0.373
1985 Simmonds MA. Antagonism of flurazepam and other effects of Ro15-1788, PK8165 and Ro5-4864 on the GABA-A receptor complex in rat cuneate nucleus. European Journal of Pharmacology. 117: 51-60. PMID 3002803 DOI: 10.1016/0014-2999(85)90471-6  0.58
1985 Harrison NL, Simmonds MA. Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex. British Journal of Pharmacology. 84: 381-91. PMID 2858237 DOI: 10.1111/J.1476-5381.1985.Tb12922.X  0.547
1984 File SE, Simmonds MA. Interactions of two phenylquinolines with picrotoxin and benzodiazepines in vivo and in vitro. European Journal of Pharmacology. 97: 295-300. PMID 6705827 DOI: 10.1016/0014-2999(84)90463-1  0.601
1984 Newberry NR, Simmonds MA. The rat gracile nucleus in vitro: III. Unitary spike potentials and their conditioned inhibition. Brain Research. 303: 59-65. PMID 6329473 DOI: 10.1016/0006-8993(84)90210-5  0.327
1984 Newberry NR, Simmonds MA. The rat gracile nucleus in vitro: I. Evidence for a GABA-mediated depolarisation of the dorsal column afferents. Brain Research. 303: 41-9. PMID 6329471 DOI: 10.1016/0006-8993(84)90208-7  0.515
1984 Harrison NL, Simmonds MA. Modulation of the GABA receptor complex by a steroid anaesthetic. Brain Research. 323: 287-92. PMID 6098342 DOI: 10.1016/0006-8993(84)90299-3  0.726
1984 Simmonds MA. The GABA Receptors, S.J. Enna (Ed.). The Humana Press (1983), xvi + 341, ISBN: 0 89603 055 5 Trends in Neurosciences. 7: 2-2. DOI: 10.1016/S0166-2236(84)80223-4  0.544
1984 Simmonds MA, Turner JP, Harrison NL. Interactions of steroids with the GABA-A receptor complex Neuropharmacology. 23: 877-878. DOI: 10.1016/0028-3908(84)90290-9  0.731
1983 Simmonds MA. Depolarizing responses to glycine, beta-alanine and muscimol in isolated optic nerve and cuneate nucleus. British Journal of Pharmacology. 79: 799-806. PMID 6418249 DOI: 10.1111/J.1476-5381.1983.Tb10018.X  0.504
1983 Harrison NL, Simmonds MA. Two distinct interactions of barbiturates and chlormethiazole with the GABAA receptor complex in rat cuneate nucleus in vitro. British Journal of Pharmacology. 80: 387-94. PMID 6317133 DOI: 10.1111/J.1476-5381.1983.Tb10045.X  0.69
1983 Harrison NL, Simmonds MA. The picrotoxin-like action of a convulsant benzodiazepine, Ro5-3663. European Journal of Pharmacology. 87: 155-8. PMID 6301850 DOI: 10.1016/0014-2999(83)90064-X  0.695
1983 Simmonds MA. Variations in response of the GABA-picrotoxin-benzodiazepine receptor complex to flurazepam. Pharmacology, Biochemistry, and Behavior. 18: 299-301. PMID 6300935 DOI: 10.1016/0091-3057(83)90382-9  0.462
1983 Simmonds MA. Multiple GABA receptors and associated regulatory sites Trends in Neurosciences. 6: 279-281. DOI: 10.1016/0166-2236(83)90119-4  0.569
1982 Cain CR, Simmonds MA. GABA-mediated changes in excitability of the rat lateral olfactory tract in vitro. The Journal of Physiology. 332: 487-99. PMID 7153936  0.43
1982 Harrison NL, Simmonds MA. Sodium valproate enhances responses to GABA receptor activation only at high concentrations. Brain Research. 250: 201-4. PMID 6291721 DOI: 10.1016/0006-8993(82)90971-4  0.693
1982 Simmonds MA. Classification of some GABA antagonists with regard to site of action and potency in slices of rat cuneate nucleus. European Journal of Pharmacology. 80: 347-58. PMID 6286323 DOI: 10.1016/0014-2999(82)90080-2  0.63
1982 Cain CR, Simmonds MA. Effects of baclofen on the olfactory cortex slice preparation. Neuropharmacology. 21: 371-3. PMID 6283413 DOI: 10.1016/0028-3908(82)90103-4  0.453
1981 Simmonds MA. Distinction between the effects of barbiturates, benzodiazepines and phenytoin on responses to gamma-aminobutyric acid receptor activation and antagonism by bicuculline and picrotoxin. British Journal of Pharmacology. 73: 739-47. PMID 6265019  0.405
1981 Simmonds MA. Pentobarbitone and phenobarbitone interact differently with the γ-aminobutyric acid antagonists bicuculline and picrotoxin British Journal of Pharmacology. 73: 229P-230P.  0.329
1980 Simmonds MA. Evidence that bicuculline and picrotoxin act at separate sites to antagonize gamma-aminobutyric acid in rat cuneate nucleus. Neuropharmacology. 19: 39-45. PMID 7360330 DOI: 10.1016/0028-3908(80)90164-1  0.339
1980 Simmonds MA. A site for the potentiation of GABA-mediated responses by benzodiazepines. Nature. 284: 558-60. PMID 6245368  0.556
1978 Hayes AG, Simmonds MA. Effects of gamma-aminobutyric acid on nerve terminal excitability in a slice preparation of cuneate nucleus. British Journal of Pharmacology. 63: 503-7. PMID 667494 DOI: 10.1111/J.1476-5381.1978.Tb07804.X  0.506
1978 Simmonds MA. Presynaptic actions of gamma-aminobutyric acid and some antagonists in a slice preparation of cuneate nucleus. British Journal of Pharmacology. 63: 495-502. PMID 667493 DOI: 10.1111/J.1476-5381.1978.Tb07803.X  0.613
1977 Dray A, Fowler LJ, Oakley NR, Simmonds MA, Tanner T. Regulation of nigro-striatal dopaminergic neurotransmission in the rat. Neuropharmacology. 16: 511-8. PMID 199852 DOI: 10.1016/0028-3908(77)90010-7  0.399
1976 Hill RG, Simmonds MA, Straughan DW. Antagonism of gamma-aminobutyric acid and glycine by convulsants in the cuneate nucleus of cat. British Journal of Pharmacology. 56: 9-19. PMID 1252667 DOI: 10.1111/j.1476-5381.1976.tb06952.x  0.735
1975 Dray A, Fowler LJ, Oakley NR, Simmonds MA, Tanner T. Proceedings: Comparison of circling behaviour following unilateral inhibition of GABA-transaminase or discrete electroyltic lesioning in the rat substantia nigra. British Journal of Pharmacology. 55: 288P. PMID 1238134  0.397
1975 Dray, Oakley NR, Simmonds MA. Rotational behaviour following inhibition of GABA metabolism unilaterally in the rat substantia nigra. The Journal of Pharmacy and Pharmacology. 27: 627-9. PMID 239186 DOI: 10.1111/J.2042-7158.1975.Tb09523.X  0.505
1974 Sutton I, Simmonds MA. The selective blockade by diaminobutyric acid of neuronal uptake of (3H)GABA in rat brain in vivo. Journal of Neurochemistry. 23: 273-4. PMID 4855081  0.389
1974 Hill RG, Simmonds MA, Straughan DW. Proceedings: Effects on synaptic inhibition in the cuneate nucleus produced by stereoisomers of bicuculline methochloride. The Journal of Physiology. 239: 122P-123P. PMID 4415256  0.582
1974 Sutton I, Simmonds MA. Effects of acute and chronic pentobarbitone on the gamma-aminobutyric acid system in rat brain. Biochemical Pharmacology. 23: 1801-8. PMID 4156468 DOI: 10.1016/0006-2952(74)90188-9  0.563
1974 Hill RG, Simmonds MA, Straughan DW. Proceedings: Convulsant substances as antagonists of GABA and presynaptic inhibition in the cuneate nucleus. British Journal of Pharmacology. 52: 117P. PMID 4155980  0.719
1974 Hill RG, Simmonds MA, Straughan DW. Convulsant substances as antagonists of GABA and presynaptic inhibition in the cuneate nucleus Brit.J.Pharmacol.. 52.  0.719
1973 Hill RG, Simmonds MA, Straughan DW. Microiontophoretic study of depressant amino acids and the specificity of their antagonists. British Journal of Pharmacology. 47: 663P-664P. PMID 4730874  0.525
1973 Hill RG, Simmonds MA, Straughan DW. Amino acid antagonists and the depression of cuneate neurones by -aminobutyric acid (GABA) and glycine. British Journal of Pharmacology. 47: 642P-643P. PMID 4730857  0.644
1973 Hill RG, Simmonds MA. A method for comparing the potencies of -aminobutyric acid antagonists on single cortical neurones using micro-iontophoretic techniques. British Journal of Pharmacology. 48: 1-11. PMID 4724192  0.481
1973 Sutton U, Simmonds MA. Effects of acute and chronic ethanol on the gamma-amino-butyric acid system in rat brain. Biochemical Pharmacology. 22: 1685-92. PMID 4715990 DOI: 10.1016/0006-2952(73)90381-X  0.55
1973 Hill RG, Simmonds MA, Straughan DW. Proceedings: Presynaptic inhibition and the depressant actions of GABA and glycine in the feline cuneate nucleus: changes related to electrographic seizure activity. The Journal of Physiology. 234: 83P-84P. PMID 4358356  0.65
1973 Hill RG, Simmonds MA, Straughan DW. A comparative study of some convulsant substances as gamma-aminobutyric acid antagonists in the feline cerebral cortex. British Journal of Pharmacology. 49: 37-51. PMID 4150764 DOI: 10.1111/J.1476-5381.1973.Tb08266.X  0.74
1973 Hill RG, Simmonds MA, Straughan DW. (+) Tubocurarine: effects on inhibitory mechanisms in CNS Naunyn-Schmied.Arch.Pharm.. 279: 40.  0.551
1972 Hill RG, Simmonds MA, Straughan DW. Blockade of central GABA receptors and the convulsive actions of bicuculline, picrotoxin and leptazol. British Journal of Pharmacology. 45: 176P-177P. PMID 5041490  0.726
1972 Hill RG, Simmonds MA, Straughan DW. Antagonism of GABA by picrotoxin in the feline cerebral cortex. British Journal of Pharmacology. 44: 807-9. PMID 5041455 DOI: 10.1111/J.1476-5381.1972.Tb07319.X  0.734
1972 Hill RG, Simmonds MA, Straughan DW. Convulsive properties of d-tubocurarine and cortical inhibition. Nature. 240: 51-2. PMID 4570640 DOI: 10.1038/240051a0  0.692
1971 Hill RG, Simmonds MA, Straughan DW. Evidence that bicuculline can both potentiate and antagonize GABA. British Journal of Pharmacology. 42: 639P-640P. PMID 5116042  0.715
1971 Straughan DW, Neal MJ, Simmonds MA, Collins GG, Hill RG. Evaluation of bicuculline as a GABA antagonist. Nature. 233: 352-4. PMID 4940434 DOI: 10.1038/233352a0  0.713
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