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Roderick MacKinnon - Related publications

Rockefeller University, New York, NY, United States 
Ion channels
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50 most relevant papers in past 60 days:
Year Citation  Score
2019 Wulff H, Christophersen P, Colussi P, Chandy KG, Yarov-Yarovoy V. Antibodies and venom peptides: new modalities for ion channels. Nature Reviews. Drug Discovery. PMID 30728472 DOI: 10.1038/s41573-019-0013-8   
2019 Zakany F, Pap P, Papp F, Kovacs T, Nagy P, Peter M, Szente L, Panyi G, Varga Z. Determining the target of membrane sterols on voltage-gated potassium channels. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 1864: 312-325. PMID 30553843 DOI: 10.1016/j.bbalip.2018.12.006   
2019 Jekhmane S, Medeiros-Silva J, Li J, Kümmerer F, Müller-Hermes C, Baldus M, Roux B, Weingarth M. Shifts in the selectivity filter dynamics cause modal gating in K channels. Nature Communications. 10: 123. PMID 30631074 DOI: 10.1038/s41467-018-07973-6   
2019 Asfaw TN, Bondarenko VE. A Mathematical Model of the Human Cardiac Na Channel. The Journal of Membrane Biology. 252: 77-103. PMID 30637460 DOI: 10.1007/s00232-018-00058-x   
2019 Brown BM, Nguyen HM, Wulff H. Recent advances in our understanding of the structure and function of more unusual cation channels. F1000research. 8. PMID 30755796 DOI: 10.12688/f1000research.17163.1   
2019 George LF, Pradhan SJ, Mitchell D, Josey M, Casey J, Belus MT, Dahal GR, Bates EA. Ion Channel Contributions to Wing Development in . G3 (Bethesda, Md.). PMID 30733380 DOI: 10.1534/g3.119.400028   
2019 Xin P, Kong H, Sun Y, Zhao L, Fang H, Zhu H, Jiang T, Guo J, Zhang Q, Dong W, Chen CP. Highly Selective Artificial K+ Channels Formed by Pillararene-Cyclodextrin Hybrid Molecules: Tuning the Cation Selectivity and Generating Membrane Potential. Angewandte Chemie (International Ed. in English). PMID 30648810 DOI: 10.1002/anie.201813797   
2019 Okada Y, Okada T, Sato-Numata K, Islam MR, Ando-Akatsuka Y, Numata T, Kubo M, Shimizu T, Kurbannazarova RS, Marunaka Y, Sabirov RZ. Cell Volume-Activated and Volume-Correlated Anion Channels in Mammalian Cells: Their Biophysical, Molecular, and Pharmacological Properties. Pharmacological Reviews. 71: 49-88. PMID 30573636 DOI: 10.1124/pr.118.015917   
2019 Miller AN, Vaisey G, Long SB. Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin. Elife. 8. PMID 30628889 DOI: 10.7554/eLife.43231   
2019 Cowgill J, Klenchin VA, Alvarez-Baron C, Tewari D, Blair A, Chanda B. Bipolar switching by HCN voltage sensor underlies hyperpolarization activation. Proceedings of the National Academy of Sciences of the United States of America. 116: 670-678. PMID 30587580 DOI: 10.1073/pnas.1816724116   
2019 Weiss N, Zamponi GW. T-type calcium channels: From molecule to therapeutic opportunities. The International Journal of Biochemistry & Cell Biology. 108: 34-39. PMID 30648620 DOI: 10.1016/j.biocel.2019.01.008   
2019 Haley E, Choi W, Fan C, Sun W, Du J, Lü W. Expression and Purification of the Human Lipid-sensitive Cation Channel TRPC3 for Structural Determination by Single-particle Cryo-electron Microscopy. Journal of Visualized Experiments : Jove. PMID 30663716 DOI: 10.3791/58754   
2019 Xu H, Li T, Rohou A, Arthur CP, Tzakoniati F, Wong E, Estevez A, Kugel C, Franke Y, Chen J, Ciferri C, Hackos DH, Koth CM, Payandeh J. Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin. Cell. PMID 30661758 DOI: 10.1016/j.cell.2018.12.018   
2019 Barros F, Pardo LA, Domínguez P, Sierra LM, de la Peña P. New Structures and Gating of Voltage-Dependent Potassium (Kv) Channels and Their Relatives: A Multi-Domain and Dynamic Question. International Journal of Molecular Sciences. 20. PMID 30634573 DOI: 10.3390/ijms20020248   
2019 Vishwakarma VK, Upadhyay PK, Chaurasiya HS, Srivasatav RK, Ansari TM, Srivastava V. Mechanistic Pathways of ATP Sensitive Potassium Channels Referring to Cardio-Protective Effects and Cellular Functions. Drug Research. PMID 30609434 DOI: 10.1055/a-0806-7207   
2019 Liu Y, Wang P, Ma F, Zheng M, Liu G, Kume S, Kurokawa T, Ono K. Asparagine-linked glycosylation modifies voltage-dependent gating properties of Ca3.1-T-type Ca channel. The Journal of Physiological Sciences : Jps. PMID 30600443 DOI: 10.1007/s12576-018-0650-4   
2019 Shoji K, Kawano R, White RJ. Spatially-Resolved Chemical Detection with a Nanoneedle-Probe-Supported Biological Nanopore. Acs Nano. PMID 30724558 DOI: 10.1021/acsnano.8b09667   
2019 Clairfeuille T, Cloake A, Infield DT, Llongueras JP, Arthur CP, Li ZR, Jian Y, Martin-Eauclaire MF, Bougis PE, Ciferri C, Ahern CA, Bosmans F, Hackos DH, Rohou A, Payandeh J. Structural basis of α-scorpion toxin action on Nav channels. Science (New York, N.Y.). PMID 30733386 DOI: 10.1126/science.aav8573   
2019 Zhang L, Wang K, Klaerke DA, Calloe K, Lowrey L, Pedersen PA, Gourdon P, Gotfryd K. Purification of Functional Human TRP Channels Recombinantly Produced in Yeast. Cells. 8. PMID 30754715 DOI: 10.3390/cells8020148   
2019 Zheng W, Gracheva EO, Bagriantsev SN. A hydrophobic gate in the inner pore helix is the major determinant of inactivation in mechanosensitive Piezo channels. Elife. 8. PMID 30628892 DOI: 10.7554/eLife.44003   
2019 El Ghaleb Y, Campiglio M, Flucher BE. Correcting the R165K substitution in the first voltage-sensor of Ca1.1 right-shifts the voltage-dependence of skeletal muscle calcium channel activation. Channels (Austin, Tex.). PMID 30638110 DOI: 10.1080/19336950.2019.1568825   
2019 Zhao S, Restrepo-Pérez L, Soskine M, Maglia G, Joo C, Dekker C, Aksimentiev A. Electro-Mechanical Conductance Modulation of a Nanopore Using a Removable Gate. Acs Nano. PMID 30715850 DOI: 10.1021/acsnano.8b09266   
2019 Shi EY, Yuan CL, Sipple MT, Srinivasan J, Ptak CP, Oswald RE, Nowak LM. Noncompetitive antagonists induce cooperative AMPA receptor channel gating. The Journal of General Physiology. PMID 30622133 DOI: 10.1085/jgp.201812209   
2019 Fryatt AG, Dayl S, Stavrou A, Schmid R, Evans RJ. Organization of ATP-gated P2X1 receptor intracellular termini in apo and desensitized states. The Journal of General Physiology. PMID 30626615 DOI: 10.1085/jgp.201812108   
2019 Tanguay J, Callahan KM, D'Avanzo N. Characterization of drug binding within the HCN1 channel pore. Scientific Reports. 9: 465. PMID 30679654 DOI: 10.1038/s41598-018-37116-2   
2019 Uchida K, Nomura M, Yamamoto T, Ogawa Y, Teramoto N. Rab8a is involved in membrane trafficking of Kir6.2 in the MIN6 insulinoma cell line. Pflugers Archiv : European Journal of Physiology. PMID 30631919 DOI: 10.1007/s00424-018-02252-1   
2019 Johnson CN. Calcium modulation of cardiac sodium channels. The Journal of Physiology. PMID 30707447 DOI: 10.1113/JP277553   
2019 Chen J, Xue L, Wei R, Liu S, Yin CC. The insecticide chlorantraniliprole is a weak activator of mammalian skeletal ryanodine receptor/Ca release channel. Biochemical and Biophysical Research Communications. 508: 633-639. PMID 30527809 DOI: 10.1016/j.bbrc.2018.11.180   
2019 Valinsky WC, Touyz RM, Shrier A. Aldosterone and Ion Channels. Vitamins and Hormones. 109: 105-131. PMID 30678852 DOI: 10.1016/bs.vh.2018.10.004   
2019 Sancho M, Gao Y, Hald BO, Yin H, Boulton M, Steven D, MacDougall K, Parrent A, Pickering JG, Welsh D. An Assessment of K Channel Function in Human Cerebral Arteries. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30681365 DOI: 10.1152/ajpheart.00022.2019   
2019 Csanády L, Vergani P, Gadsby DC. STRUCTURE, GATING, AND REGULATION OF THE CFTR ANION CHANNEL. Physiological Reviews. 99: 707-738. PMID 30516439 DOI: 10.1152/physrev.00007.2018   
2019 Wong KK, Banham AH, Yaacob NS, Nur Husna SM. The oncogenic roles of TRPM ion channels in cancer. Journal of Cellular Physiology. PMID 30710353 DOI: 10.1002/jcp.28168   
2019 Argudo D, Capponi S, Bethel NP, Grabe M. A multiscale model of mechanotransduction by the ankyrin chains of the NOMPC channel. The Journal of General Physiology. PMID 30728217 DOI: 10.1085/jgp.201812266   
2019 Belau F, Metzner K, Christ T, Ravens U, Schaefer M, Künzel S, Li W, Wettwer E, Dobrev D, El-Armouche A, Kämmerer S. DPP10 is a new regulator of Nav1.5 channels in human heart. International Journal of Cardiology. PMID 30638748 DOI: 10.1016/j.ijcard.2018.12.072   
2019 Garcia-Caballero A, Gandini MA, Huang S, Chen L, Souza IA, Dang YL, Stutts MJ, Zamponi GW. Cav3.2 calcium channel interactions with the epithelial sodium channel ENaC. Molecular Brain. 12: 12. PMID 30736831 DOI: 10.1186/s13041-019-0433-8   
2019 Startek JB, Boonen B, Talavera K, Meseguer V. TRP Channels as Sensors of Chemically-Induced Changes in Cell Membrane Mechanical Properties. International Journal of Molecular Sciences. 20. PMID 30654572 DOI: 10.3390/ijms20020371   
2019 Krause BS, Kaufmann JCD, Kuhne J, Vierock J, Huber T, Sakmar TP, Gerwert K, Bartl F, Hegemann P. Tracking pore hydration in channelrhodopsin by site-directed infrared-active azido probes. Biochemistry. PMID 30702875 DOI: 10.1021/acs.biochem.8b01211   
2019 Johnson B, Leek AN, Tamkun MM. Kv2 channels create endoplasmic reticulum / plasma membrane junctions: a brief history of Kv2 channel subcellular localization. Channels (Austin, Tex.). 13: 88-101. PMID 30712450 DOI: 10.1080/19336950.2019.1568824   
2019 Bonhenry D, Schober R, Schmidt T, Waldherr L, Ettrich RH, Schindl R. Mechanistic insights into the Orai channel by molecular dynamics simulations. Seminars in Cell & Developmental Biology. PMID 30639326 DOI: 10.1016/j.semcdb.2019.01.002   
2019 Bartsch A, Llabrés S, Pein F, Kattner C, Schön M, Diehn M, Tanabe M, Munk A, Zachariae U, Steinem C. High-resolution experimental and computational electrophysiology reveals weak β-lactam binding events in the porin PorB. Scientific Reports. 9: 1264. PMID 30718567 DOI: 10.1038/s41598-018-37066-9   
2019 Kumar A, Pisula W, Müllen K. One Dimensional Enhanced Anhydrous Proton Conduction in Well Defined Molecular Columns Induced by Non-Covalent Interactions. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. PMID 30702798 DOI: 10.1002/cphc.201801017   
2019 Gao P, Yan Z, Zhu Z. The role of adipose TRP channels in the pathogenesis of obesity. Journal of Cellular Physiology. PMID 30618095 DOI: 10.1002/jcp.28106   
2019 Crnjar A, Comitani F, Hester W, Molteni C. Trans- Cis Proline Switches in a Pentameric Ligand-Gated Ion Channel: How They Are Affected by and How They Affect the Biomolecular Environment. The Journal of Physical Chemistry Letters. 10: 694-700. PMID 30668119 DOI: 10.1021/acs.jpclett.8b03431   
2019 van der Peet PL, Sandanayake S, Jarrott B, Williams SJ. Discovery of N-Aryloxypropylbenzylamines as Voltage-gated Sodium Channel NaV1.2 subtype Selective Inhibitors. Chemmedchem. PMID 30676691 DOI: 10.1002/cmdc.201800781   
2019 Liu Y, Yu Y, Sun J, Cao Q, Tang Z, Liu M, Xu T, Ma D, Li Z, Sun J. Root-zone-specific sensitivity of K+-and Ca2+-permeable channels to H2O2 determines ion homeostasis in salinized diploid and hexaploid Ipomoea trifida. Journal of Experimental Botany. PMID 30689932 DOI: 10.1093/jxb/ery461   
2019 Moeder W, Phan V, Yoshioka K. Ca to the rescue - Cachannels and signaling in plant immunity. Plant Science : An International Journal of Experimental Plant Biology. 279: 19-26. PMID 30709488 DOI: 10.1016/j.plantsci.2018.04.012   
2019 Coyote-Maestas W, He Y, Myers CL, Schmidt D. Domain insertion permissibility-guided engineering of allostery in ion channels. Nature Communications. 10: 290. PMID 30655517 DOI: 10.1038/s41467-018-08171-0   
2019 Lagostena L, Zifarelli G, Picollo A. New Insights into the Mechanism of NO Selectivity in the Human Kidney Chloride Channel ClC-Ka and the CLC Protein Family. Journal of the American Society of Nephrology : Jasn. PMID 30635372 DOI: 10.1681/ASN.2018060593   
2019 Pugsley MK, Yong SL, Goldin AL, Hayes ES, Walker MJA. Molecular charge associated with antiarrhythmic actions in a series of amino-2-cyclohexyl ester derivatives. European Journal of Pharmacology. 844: 241-252. PMID 30571955 DOI: 10.1016/j.ejphar.2018.12.025   
2019 Tai YS, Yang SC, Hsieh YC, Huang YB, Wu PC, Tsai MJ, Tsai YH, Lin MW. A Novel Model for Studying Voltage-Gated Ion Channel Gene Expression during Reversible Ischemic Stroke. International Journal of Medical Sciences. 16: 60-67. PMID 30662329 DOI: 10.7150/ijms.27442