| Year |
Citation |
Score |
| 2017 |
Bakouh N, Bellanca S, Nyboer B, Moliner Cubel S, Karim Z, Sanchez CP, Stein WD, Planelles G, Lanzer M. Iron is a substrate of the Plasmodium falciparum chloroquine resistance transporter PfCRT in Xenopus oocytes. The Journal of Biological Chemistry. PMID 28768767 DOI: 10.1074/jbc.M117.805200 |
0.322 |
|
| 2014 |
Bellanca S, Summers RL, Meyrath M, Dave A, Nash MN, Dittmer M, Sanchez CP, Stein WD, Martin RE, Lanzer M. Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites. The Journal of Biological Chemistry. 289: 36336-51. PMID 25378409 DOI: 10.1074/jbc.M114.614206 |
0.355 |
|
| 2014 |
Summers RL, Dave A, Dolstra TJ, Bellanca S, Marchetti RV, Nash MN, Richards SN, Goh V, Schenk RL, Stein WD, Kirk K, Sanchez CP, Lanzer M, Martin RE. Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite's chloroquine resistance transporter. Proceedings of the National Academy of Sciences of the United States of America. 111: E1759-67. PMID 24728833 DOI: 10.1073/pnas.1322965111 |
0.322 |
|
| 2011 |
Sanchez CP, Mayer S, Nurhasanah A, Stein WD, Lanzer M. Genetic linkage analyses redefine the roles of PfCRT and PfMDR1 in drug accumulation and susceptibility in Plasmodium falciparum. Molecular Microbiology. 82: 865-78. PMID 21999470 DOI: 10.1111/j.1365-2958.2011.07855.x |
0.308 |
|
| 2010 |
Sanchez CP, Dave A, Stein WD, Lanzer M. Transporters as mediators of drug resistance in Plasmodium falciparum. International Journal For Parasitology. 40: 1109-18. PMID 20399785 DOI: 10.1016/j.ijpara.2010.04.001 |
0.338 |
|
| 2008 |
Sanchez CP, Rotmann A, Stein WD, Lanzer M. Polymorphisms within PfMDR1 alter the substrate specificity for anti-malarial drugs in Plasmodium falciparum. Molecular Microbiology. 70: 786-98. PMID 18713316 DOI: 10.1111/j.1365-2958.2008.06413.x |
0.334 |
|
| 2008 |
Steadman K, Stein WD, Litman T, Yang SX, Abu-Asab M, Dutcher SK, Bates S. PolyHEMA spheroids are an inadequate model for the drug resistance of the intractable solid tumors. Cell Cycle (Georgetown, Tex.). 7: 818-29. PMID 18239467 DOI: 10.4161/Cc.7.6.5597 |
0.32 |
|
| 2008 |
Sanchez CP, Stein WD, Lanzer M. Dissecting the components of quinine accumulation in Plasmodium falciparum. Molecular Microbiology. 67: 1081-93. PMID 18194156 DOI: 10.1111/j.1365-2958.2008.06108.x |
0.33 |
|
| 2007 |
Sanchez CP, Stein WD, Lanzer M. Is PfCRT a channel or a carrier? Two competing models explaining chloroquine resistance in Plasmodium falciparum. Trends in Parasitology. 23: 332-9. PMID 17493873 DOI: 10.1016/j.pt.2007.04.013 |
0.322 |
|
| 2007 |
Sanchez CP, Rohrbach P, McLean JE, Fidock DA, Stein WD, Lanzer M. Differences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum. Molecular Microbiology. 64: 407-20. PMID 17493125 DOI: 10.1111/J.1365-2958.2007.05664.X |
0.33 |
|
| 2006 |
Wang Y, Hao D, Stein WD, Yang L. A kinetic study of Rhodamine123 pumping by P-glycoprotein. Biochimica Et Biophysica Acta. 1758: 1671-6. PMID 16854369 DOI: 10.1016/j.bbamem.2006.06.004 |
0.34 |
|
| 2005 |
Sanchez CP, McLean JE, Rohrbach P, Fidock DA, Stein WD, Lanzer M. Evidence for a pfcrt-associated chloroquine efflux system in the human malarial parasite Plasmodium falciparum. Biochemistry. 44: 9862-70. PMID 16026158 DOI: 10.1021/Bi050061F |
0.34 |
|
| 2005 |
Stein WD, Litman T, Fojo T, Bates SE. Differential expression of cell adhesion genes: implications for drug resistance. International Journal of Cancer. Journal International Du Cancer. 113: 861-5. PMID 15514970 DOI: 10.1002/Ijc.20671 |
0.33 |
|
| 2004 |
Sanchez CP, McLean JE, Stein W, Lanzer M. Evidence for a substrate specific and inhibitable drug efflux system in chloroquine resistant Plasmodium falciparum strains. Biochemistry. 43: 16365-73. PMID 15610031 DOI: 10.1021/Bi048241X |
0.338 |
|
| 2004 |
Bates SE, Bakke S, Kang M, Robey RW, Zhai S, Thambi P, Chen CC, Patil S, Smith T, Steinberg SM, Merino M, Goldspiel B, Meadows B, Stein WD, Choyke P, et al. A phase I/II study of infusional vinblastine with the P-glycoprotein antagonist valspodar (PSC 833) in renal cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 4724-33. PMID 15269145 DOI: 10.1158/1078-0432.Ccr-0829-03 |
0.313 |
|
| 2004 |
Stein WD, Bates SE, Fojo T. Intractable cancers: the many faces of multidrug resistance and the many targets it presents for therapeutic attack. Current Drug Targets. 5: 333-46. PMID 15134216 DOI: 10.2174/1389450043345489 |
0.322 |
|
| 2004 |
Stein WD, Litman T, Fojo T, Bates SE. A Serial Analysis of Gene Expression (SAGE) database analysis of chemosensitivity: comparing solid tumors with cell lines and comparing solid tumors from different tissue origins. Cancer Research. 64: 2805-16. PMID 15087397 DOI: 10.1158/0008-5472.Can-03-3383 |
0.308 |
|
| 2003 |
Litman T, Skovsgaard T, Stein WD. Pumping of drugs by P-glycoprotein: a two-step process? The Journal of Pharmacology and Experimental Therapeutics. 307: 846-53. PMID 14534356 DOI: 10.1124/jpet.103.056960 |
0.34 |
|
| 2003 |
Sanchez CP, Stein W, Lanzer M. Trans stimulation provides evidence for a drug efflux carrier as the mechanism of chloroquine resistance in Plasmodium falciparum. Biochemistry. 42: 9383-94. PMID 12899625 DOI: 10.1021/bi034269h |
0.334 |
|
| 2003 |
Stein WD, Robey R, Cardarelli C, Gottesman MM, Bates SE. Low and high concentrations of the topo II inhibitor daunorubicin in NIH3T3 cells: reversible G2/M versus irreversible G1 and S arrest. Cell Cycle (Georgetown, Tex.). 2: 134-42. PMID 12695665 DOI: 10.4161/Cc.2.2.294 |
0.305 |
|
| 2002 |
Stein WD. Cell volume homeostasis: ionic and nonionic mechanisms. The sodium pump in the emergence of animal cells. International Review of Cytology. 215: 231-58. PMID 11952230 DOI: 10.1016/S0074-7696(02)15011-X |
0.336 |
|
| 2001 |
Hoshen MB, Stein WD, Ginsburg HD. Pharmacokinetic-pharmacodynamic modelling of the antimalarial activity of mefloquine. Parasitology. 123: 337-46. PMID 11676365 DOI: 10.1017/S003118200100854X |
0.301 |
|
| 2001 |
Litman T, Druley TE, Stein WD, Bates SE. From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance. Cellular and Molecular Life Sciences : Cmls. 58: 931-59. PMID 11497241 DOI: 10.1007/Pl00000912 |
0.366 |
|
| 2001 |
Ruth A, Stein WD, Rose E, Roninson IB. Coordinate changes in drug resistance and drug-induced conformational transitions in altered-function mutants of the multidrug transporter P-glycoprotein. Biochemistry. 40: 4332-9. PMID 11284689 DOI: 10.1021/bi001373f |
0.319 |
|
| 2001 |
Druley TE, Stein WD, Ruth A, Roninson IB. P-glycoprotein-mediated colchicine resistance in different cell lines correlates with the effects of colchicine on P-glycoprotein conformation. Biochemistry. 40: 4323-31. PMID 11284688 DOI: 10.1021/bi001372n |
0.342 |
|
| 2001 |
Druley TE, Stein WD, Roninson IB. Analysis of MDR1 P-glycoprotein conformational changes in permeabilized cells using differential immunoreactivity. Biochemistry. 40: 4312-22. PMID 11284687 DOI: 10.1021/bi001371v |
0.324 |
|
| 1998 |
Stein WD. Kinetics of the P-glycoprotein, the multidrug transporter. Experimental Physiology. 83: 221-32. PMID 9568482 DOI: 10.1113/Expphysiol.1998.Sp004106 |
0.314 |
|
| 1997 |
Mechetner EB, Schott B, Morse BS, Stein WD, Druley T, Davis KA, Tsuruo T, Roninson IB. P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity. Proceedings of the National Academy of Sciences of the United States of America. 94: 12908-13. PMID 9371774 DOI: 10.1073/pnas.94.24.12908 |
0.339 |
|
| 1997 |
Litman T, Zeuthen T, Skovsgaard T, Stein WD. Competitive, non-competitive and cooperative interactions between substrates of P-glycoprotein as measured by its ATPase activity. Biochimica Et Biophysica Acta. 1361: 169-76. PMID 9300798 DOI: 10.1016/S0925-4439(97)00027-6 |
0.31 |
|
| 1997 |
Litman T, Zeuthen T, Skovsgaard T, Stein WD. Structure-activity relationships of P-glycoprotein interacting drugs: kinetic characterization of their effects on ATPase activity. Biochimica Et Biophysica Acta. 1361: 159-68. PMID 9300797 DOI: 10.1016/S0925-4439(97)00026-4 |
0.321 |
|
| 1997 |
Litman T, Nielsen D, Skovsgaard T, Zeuthen T, Stein WD. ATPase activity of P-glycoprotein related to emergence of drug resistance in Ehrlich ascites tumor cell lines. Biochimica Et Biophysica Acta. 1361: 147-58. PMID 9300796 DOI: 10.1016/S0925-4439(97)00025-2 |
0.334 |
|
| 1997 |
Ambudkar SV, Cardarelli CO, Pashinsky I, Stein WD. Relation between the turnover number for vinblastine transport and for vinblastine-stimulated ATP hydrolysis by human P-glycoprotein. The Journal of Biological Chemistry. 272: 21160-6. PMID 9261121 DOI: 10.1074/jbc.272.34.21160 |
0.347 |
|
| 1996 |
Lan LB, Ayesh S, Lyubimov E, Pashinsky I, Stein WD. Kinetic parameters for reversal of the multidrug pump as measured for drug accumulation and cell killing. Cancer Chemotherapy and Pharmacology. 38: 181-90. PMID 8616910 DOI: 10.1007/s002800050468 |
0.339 |
|
| 1996 |
Stein WD, Hoshen MB. The role of ligand-binding proteins in increasing the transcellular flux of metabolites, in particular that of calcium, bilirubin, and fatty acids Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 115: 307-312. DOI: 10.1016/S0305-0491(96)00177-0 |
0.314 |
|
| 1995 |
Lyubimov E, Lan LB, Pashinsky I, Ayesh S, Stein WD. Saturation reversal of the multidrug pump using many reversers in low-dose combinations. Anti-Cancer Drugs. 6: 727-35. PMID 8845484 DOI: 10.1097/00001813-199512000-00003 |
0.35 |
|
| 1995 |
Stein WD. The sodium pump in the evolution of animal cells. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 349: 263-9. PMID 8577837 DOI: 10.1098/rstb.1995.0112 |
0.333 |
|
| 1994 |
Gottesman MM, Currier S, Bruggemann E, Lelong I, Stein W, Pastan I. Chapter 1 The Multidrug Transporter: Mechanistic Considerations Current Topics in Membranes. 41: 3-17. DOI: 10.1016/S0070-2161(08)60451-7 |
0.394 |
|
| 1991 |
Ginsburg H, Stein WD. Kinetic modelling of chloroquine uptake by malaria-infected erythrocytes. Assessment of the factors that may determine drug resistance. Biochemical Pharmacology. 41: 1463-70. PMID 1826839 DOI: 10.1016/0006-2952(91)90562-J |
0.318 |
|
| 1987 |
Ginsburg H, Stein WD. New permeability pathways induced by the malarial parasite in the membrane of its host erythrocyte: potential routes for targeting of drugs into infected cells. Bioscience Reports. 7: 455-63. PMID 3322419 DOI: 10.1007/BF01116501 |
0.339 |
|
| 1987 |
Ginsburg H, Stein WD. Biophysical analysis of novel transport pathways induced in red blood cell membranes. The Journal of Membrane Biology. 96: 1-10. PMID 3295251 DOI: 10.1007/BF01869329 |
0.334 |
|
| 1983 |
Weiser MB, Razin M, Stein WD. Kinetic tests of models for sugar transport in human erythrocytes and a comparison of fresh and cold-stored cells Bba - Biomembranes. 727: 379-388. PMID 6838879 DOI: 10.1016/0005-2736(83)90423-6 |
0.363 |
|
| 1983 |
Stein WD, Klein A. Multiple controls on the intracellular trapping of uridine Bba - Molecular Cell Research. 762: 94-101. PMID 6830868 DOI: 10.1016/0167-4889(83)90121-0 |
0.341 |
|
| 1982 |
Karlish SJD, Lieb WR, Stein WD. Combined effects of ATP and phosphate on rubidium exchange mediated by Na-K-ATPase reconstituted into phospholipid vesicles Journal of Physiology. 333-350. PMID 6290648 DOI: 10.1113/jphysiol.1982.sp014267 |
0.309 |
|
| 1982 |
Karlish SJD, Stein WD. Passive rubidium fluxes mediated by Na-K-ATPase reconstituted into phospholipid vesicles when ATP- and phosphate-free Journal of Physiology. 295-316. PMID 6290646 DOI: 10.1113/jphysiol.1982.sp014265 |
0.309 |
|
| 1979 |
Foster DM, Jacquez JA, Lieb WR, Stein WD. A high affinity site for sugar transport at the inner face of the human erythrocyte membrane? Biochimica Et Biophysica Acta. 555: 349-51. PMID 476109 DOI: 10.1016/0005-2736(79)90173-1 |
0.334 |
|
| 1979 |
Heichal O, Ish-Shalom D, Koren R, Stein WD. The kinetic dissection of transport from metabolic trapping during substrate uptake by intact cells. Uridine uptake by quiescent and serum-activated nil 8 hamster cells and their murine sarcoma virus-transformed counterparts Bba - Biomembranes. 551: 169-186. PMID 218628 DOI: 10.1016/0005-2736(79)90363-8 |
0.328 |
|
| 1978 |
Goldenberg GJ, Stein WD. Increase in the affinity of the uridine phosphorylation system for ATP after serum or insulin activation of 3T3 fibroblasts Journal of Supramolecular and Cellular Biochemistry. 9: 489-496. PMID 750762 DOI: 10.1002/Jss.400090404 |
0.301 |
|
| 1978 |
Honig B, Stein WD. Design principles for active transport systems Journal of Theoretical Biology. 75: 299-305. PMID 745445 DOI: 10.1016/0022-5193(78)90336-3 |
0.338 |
|
| 1978 |
Goldenberg GJ, Stein WD. Stimulation of uridine uptake in 3T3 cells is associated with increased ATP affinity of uridine-phosphorylating system Nature. 274: 475-477. PMID 672973 DOI: 10.1038/274475A0 |
0.321 |
|
| 1977 |
Rozengurt E, Stein WD, Wigglesworth NM. Uptake of nucleosides in density-inhibited cultures of 3T3 cells [25] Nature. 267: 442-444. PMID 876360 DOI: 10.1038/267442A0 |
0.329 |
|
| 1977 |
Stein WD, Honig B. Models for the active transport of cations ⋯ The steady-state analysis Molecular and Cellular Biochemistry. 15: 27-44. PMID 865483 DOI: 10.1007/Bf01731287 |
0.344 |
|
| 1977 |
Lieb WR, Stein WD. Is there a high affinity site for sugar transport at the inner face of the human red cell membrane? Journal of Theoretical Biology. 69: 311-319. PMID 592880 DOI: 10.1016/0022-5193(77)90140-0 |
0.332 |
|
| 1976 |
Stein WD, Rosengurt E. Temperature dependence of uridine transport in quiescent and serum-stimulated 3T3 cells Bba - Biomembranes. 419: 112-118. PMID 1244857 DOI: 10.1016/0005-2736(76)90376-X |
0.321 |
|
| 1976 |
Lieb WR, Stein WD. Testing the simple carrier using irreversible inhibitors Bba - Biomembranes. 455: 913-927. PMID 999944 DOI: 10.1016/0005-2736(76)90060-2 |
0.35 |
|
| 1974 |
Lieb WR, Stein WD. Simultaneity, occlusion and the sodium pump Nature. 252: 730-732. PMID 4437628 DOI: 10.1038/252730A0 |
0.345 |
|
| 1974 |
Stein WD, Eilam Y, Lieb WR. Active transport of cations across biological membranes Annals of the New York Academy of Sciences. 227: 328-336. PMID 4275122 DOI: 10.1111/J.1749-6632.1974.Tb14397.X |
0.326 |
|
| 1973 |
Stein WD, Lieb WR, Karlish SJ, Eilam Y. A modle for active transport of sodium and potassium ions as mediated by a tetrameric enzyme Proceedings of the National Academy of Sciences of the United States of America. 70: 275-278. PMID 4265117 DOI: 10.1073/pnas.70.1.275 |
0.352 |
|
| 1972 |
Karlish SJD, Lieb WR, Ram D, Stein WD. Kinetic parameters of glucose efflux from human red blood cells under zero-trans conditions Bba - Biomembranes. 255: 126-132. PMID 5010989 DOI: 10.1016/0005-2736(72)90014-4 |
0.317 |
|
| 1972 |
Hankin BL, Lieb WR, Stein WD. Rejection criteria for the asymmetric carrier and their application to glucose transport in the human red blood cell. Biochimica Et Biophysica Acta. 288: 114-26. PMID 4640379 DOI: 10.1016/0005-2736(72)90229-5 |
0.357 |
|
| 1972 |
Lieb WR, Stein WD. Carrier and non-carrier models for sugar transport in the human red blood cell Bba - Reviews On Biomembranes. 265: 187-207. PMID 4555470 DOI: 10.1016/0304-4157(72)90002-0 |
0.311 |
|
| 1971 |
Lieb WR, Stein WD. New theory for glucose transport across membranes. Nature. 230: 108-109. PMID 5279338 DOI: 10.1038/Newbio230108A0 |
0.332 |
|
| 1971 |
Nir S, Stein WD. Two Modes of Diffusion in Liquids Journal of Chemical Physics. 55: 1598-1603. DOI: 10.1063/1.1676285 |
0.426 |
|
| 1971 |
Stein WD, Nir S. On the mass dependence of diffusion within biological membranes and polymers The Journal of Membrane Biology. 5: 246-249. DOI: 10.1007/Bf01870552 |
0.507 |
|
| 1969 |
Stein WD. Intra-protein interactions across a fluid membrane as a model for biological transport. The Journal of General Physiology. 54: 81-90. PMID 19873658 DOI: 10.1085/Jgp.54.1.81 |
0.321 |
|
| 1968 |
Stein WD. Turnover Numbers of Membrane Carriers and the Action of the Polypeptide Antibiotics Nature. 218: 570-571. PMID 5650965 DOI: 10.1038/218570A0 |
0.303 |
|
| 1967 |
Kolber AR, Stein WD. Isolation of a Protein Coded for by the Permease Gene of the Lac Operon of Escherichia coli Protoplasma. 63: 309-314. DOI: 10.1007/978-3-7091-5577-6_62 |
0.351 |
|
| 1960 |
Barnard EA, Stein WD. Some relations between enzyme activity, chemical reactivity and urea-induced disorientations in ribonuclease Bba - Biochimica Et Biophysica Acta. 37: 371-372. PMID 13796852 |
0.377 |
|
| 1959 |
Stein W, Barnard E. The histidine residue in the active centre of ribonuclease Journal of Molecular Biology. 1: 350-IN9. DOI: 10.1016/S0022-2836(59)80017-6 |
0.452 |
|
| 1959 |
Barnard E, Stein W. The histidine residue in the active centre of ribonuclease Journal of Molecular Biology. 1: 339-349. DOI: 10.1016/S0022-2836(59)80016-4 |
0.451 |
|
| 1958 |
BARNARD EA, STEIN WD. The roles of imidazole in biological systems Advances in Enzymology and Related Subjects of Biochemistry. 20: 51-110. PMID 13605980 |
0.347 |
|
| 1956 |
Stein WD, Danielli JF. Structure and function in red cell permeability Discussions of the Faraday Society. 21: 238-251. DOI: 10.1039/DF9562100238 |
0.5 |
|
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