Jason M. Cox, Ph.D. - Publications

2002 University of Arizona, Tucson, AZ 
synthesis of natural products, biological and medicinal chemistry

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Cox JM, Chu HD, Kuethe JT, Gao YD, Scapin G, Eiermann G, He H, Li X, Lyons KA, Metzger J, Petrov A, Wu JK, Xu S, Sinha-Roy R, Weber AE, et al. The discovery of novel 5,6,5- and 5,5,6-tricyclic pyrrolidines as potent and selective DPP-4 inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27106708 DOI: 10.1016/j.bmcl.2016.04.020  1
2015 Chen P, Feng D, Qian X, Apgar J, Wilkening R, Kuethe JT, Gao YD, Scapin G, Cox J, Doss G, Eiermann G, He H, Li X, Lyons KA, Metzger J, et al. Structure-activity-relationship of amide and sulfonamide analogs of omarigliptin. Bioorganic & Medicinal Chemistry Letters. PMID 26546218 DOI: 10.1016/j.bmcl.2015.10.070  1
2015 Yang C, Balsells J, Chu HD, Cox JM, Crespo A, Ma X, Contino L, Brown P, Gao S, Zamlynny B, Wiltsie J, Clemas J, Lisnock J, Gibson J, Zhou G, et al. Discovery of benzimidazole oxazolidinediones as novel and selective nonsteroidal mineralocorticoid receptor antagonists. Acs Medicinal Chemistry Letters. 6: 461-5. PMID 25941555 DOI: 10.1021/acsmedchemlett.5b00010  1
2014 Oh da Y, Walenta E, Akiyama TE, Lagakos WS, Lackey D, Pessentheiner AR, Sasik R, Hah N, Chi TJ, Cox JM, Powels MA, Di Salvo J, Sinz C, Watkins SM, Armando AM, et al. A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice. Nature Medicine. 20: 942-7. PMID 24997608 DOI: 10.1038/nm.3614  1
2014 Biftu T, Sinha-Roy R, Chen P, Qian X, Feng D, Kuethe JT, Scapin G, Gao YD, Yan Y, Krueger D, Bak A, Eiermann G, He J, Cox J, Hicks J, et al. Omarigliptin (MK-3102): a novel long-acting DPP-4 inhibitor for once-weekly treatment of type 2 diabetes. Journal of Medicinal Chemistry. 57: 3205-12. PMID 24660890 DOI: 10.1021/jm401992e  1
2014 Cox JM, Chu HD, Yang C, Shen HC, Wu Z, Balsells J, Crespo A, Brown P, Zamlynny B, Wiltsie J, Clemas J, Gibson J, Contino L, Lisnock J, Zhou G, et al. Mineralocorticoid receptor antagonists: identification of heterocyclic amide replacements in the oxazolidinedione series. Bioorganic & Medicinal Chemistry Letters. 24: 1681-4. PMID 24630411 DOI: 10.1016/j.bmcl.2014.02.057  1
2013 Biftu T, Qian X, Chen P, Feng D, Scapin G, Gao YD, Cox J, Roy RS, Eiermann G, He H, Lyons K, Salituro G, Patel S, Petrov A, Xu F, et al. Novel tetrahydropyran analogs as dipeptidyl peptidase IV inhibitors: Profile of clinical candidate (2R,3S,5R)-2- (2,5-difluorophenyl)-5-(4,6-dihydropyrrolo [3,4-c]pyrazol-5-(1H)-yl)tetrahydro-2H-pyran-3-amine (23) [corrected]. Bioorganic & Medicinal Chemistry Letters. 23: 5361-6. PMID 23972441 DOI: 10.1016/j.bmcl.2013.07.061  1
2013 Yang C, Shen HC, Wu Z, Chu HD, Cox JM, Balsells J, Crespo A, Brown P, Zamlynny B, Wiltsie J, Clemas J, Gibson J, Contino L, Lisnock J, Zhou G, et al. Discovery of novel oxazolidinedione derivatives as potent and selective mineralocorticoid receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 23: 4388-92. PMID 23777778 DOI: 10.1016/j.bmcl.2013.05.077  1
2009 Edmondson SD, Mastracchio A, Cox JM, Eiermann GJ, He H, Lyons KA, Patel RA, Patel SB, Petrov A, Scapin G, Wu JK, Xu S, Zhu B, Thornberry NA, Roy RS, et al. Aminopiperidine-fused imidazoles as dipeptidyl peptidase-IV inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 4097-101. PMID 19539471 DOI: 10.1016/j.bmcl.2009.06.011  1
2008 Smith AB, Cox JM, Furuichi N, Kenesky CS, Zheng J, Atasoylu O, Wuest WM. Total synthesis of (-)-2-epi-peloruside A. Organic Letters. 10: 5501-4. PMID 19007239 DOI: 10.1021/ol8019132  1
2007 Cox JM, Harper B, Mastracchio A, Leiting B, Sinha Roy R, Patel RA, Wu JK, Lyons KA, He H, Xu S, Zhu B, Thornberry NA, Weber AE, Edmondson SD. Discovery of 3-aminopiperidines as potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 4579-83. PMID 17562364 DOI: 10.1016/j.bmcl.2007.05.087  1
2007 Davis RW, Flores A, Barrick TA, Cox JM, Brozik SM, Lopez GP, Brozik JA. Nanoporous microbead supported bilayers: stability, physical characterization, and incorporation of functional transmembrane proteins. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 3864-72. PMID 17315891 DOI: 10.1021/la062576t  1
2006 Majumder U, Cox JM, Johnson HW, Rainier JD. Total synthesis of gambierol: the generation of the A-C and F-H subunits by using a C-glycoside centered strategy. Chemistry (Weinheim An Der Bergstrasse, Germany). 12: 1736-46. PMID 16331718 DOI: 10.1002/chem.200500993  1
2005 Crowell E, Wang G, Cox J, Platz CP, Geng L. Correlation coefficient mapping in fluorescence spectroscopy: tissue classification for cancer detection. Analytical Chemistry. 77: 1368-75. PMID 15732920 DOI: 10.1021/ac049074+  1
2005 Smith AB, Beiger JJ, Davulcu AH, Cox JM. Preparation of [1-(methoxymethylcarbamoyl)ethyl]phosphonic acid bis(2,2,2-trifluoroethyl) ester: A useful intermediate in the synthesis of Z-unsaturated N-methoxy-N-methylamides Organic Syntheses. 82: 147-156.  1
2004 Si Z, Madani N, Cox JM, Chruma JJ, Klein JC, Schön A, Phan N, Wang L, Biorn AC, Cocklin S, Chaiken I, Freire E, Smith AB, Sodroski JG. Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins. Proceedings of the National Academy of Sciences of the United States of America. 101: 5036-41. PMID 15051887 DOI: 10.1073/pnas.0307953101  1
2004 Madani N, Perdigoto AL, Srinivasan K, Cox JM, Chruma JJ, LaLonde J, Head M, Smith AB, Sodroski JG. Localized changes in the gp120 envelope glycoprotein confer resistance to human immunodeficiency virus entry inhibitors BMS-806 and #155. Journal of Virology. 78: 3742-52. PMID 15016894 DOI: 10.1128/JVI.78.7.3742-3752.2004  1
2003 Majumder U, Cox JM, Rainier JD. Synthesis of an F-H gambierol subunit using a C-glycoside-centered strategy. Organic Letters. 5: 913-6. PMID 12633104 DOI: 10.1021/ol034100w  1
2001 Geng L, Cox JM, He Y. Dynamic two-dimensional fluorescence correlation spectroscopy. Generalized correlation and experimental factors. The Analyst. 126: 1229-39. PMID 11534585 DOI: 10.1039/b102976m  1
2001 Cox JM, Rainier JD. C-glycosides to fused polycyclic ethers. An efficient entry into the A-D ring system of gambierol. Organic Letters. 3: 2919-22. PMID 11529790 DOI: 10.1016/S0040-4020(02)00057-1  1
2001 He Y, Wang G, Cox J, Geng L. Two-dimensional fluorescence correlation spectroscopy with modulated excitation Analytical Chemistry. 73: 2302-2309. PMID 11393856 DOI: 10.1021/ac001261u  1
2001 Rainier JD, Allwein SP, Cox JM. C-glycosides to fused polycyclic ethers. A formal synthesis of (+/-)-hemibrevetoxin B. The Journal of Organic Chemistry. 66: 1380-6. PMID 11312970 DOI: 10.1021/jo001514j  1
2001 Snitsarev V, Budde T, Stricker TP, Cox JM, Krupa DJ, Geng L, Kay AR. Fluorescent detection of Zn(2+)-rich vesicles with Zinquin: mechanism of action in lipid environments. Biophysical Journal. 80: 1538-46. PMID 11222314 DOI: 10.1016/S0006-3495(01)76126-7  1
2001 Rainier JD, Cox JM, Allwein SP. Enol ether-olefin ring closing metathesis using the Grubbs ruthenium imidazole catalyst Tetrahedron Letters. 42: 179-181. DOI: 10.1016/S0040-4039(00)01943-2  1
2000 Rainier JD, Cox JM. Aluminum- and boron-mediated c-glycoside synthesis from 1,2-anhydroglycosides. Organic Letters. 2: 2707-9. PMID 10990433  1
2000 Rainier JD, Allwein SP, Cox JM. A highly efficient synthesis of the hemibrevetoxin B ring system. Organic Letters. 2: 231-4. PMID 10814289  1
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