Ishan Capila, Ph.D. - Publications

Affiliations: 
2001 University of Iowa, Iowa City, IA 
Area:
Heparin

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Pradines JR, Farutin V, Cilfone NA, Ghavami A, Kurtagic E, Guess J, Manning AM, Capila I. Enhancing reproducibility of gene expression analysis with known protein functional relationships: The concept of well-associated protein. Plos Computational Biology. 16: e1007684. PMID 32058996 DOI: 10.1371/journal.pcbi.1007684  0.36
2019 Farutin V, Prod'homme T, McConnell K, Washburn N, Halvey P, Etzel CJ, Guess J, Duffner J, Getchell K, Meccariello R, Gutierrez B, Honan C, Zhao G, Cilfone NA, Gunay NS, ... ... Capila I, et al. Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor. Arthritis Research & Therapy. 21: 216. PMID 31647025 DOI: 10.1186/s13075-019-1999-3  0.52
2019 Lech M, Guess J, Duffner J, Oyamada J, Shimizu C, Hoshino S, Farutin V, Bulik DA, Gutierrez B, Sarvaiya H, Kapoor B, Koppes L, Saldova R, Stockmann H, Albrecht S, ... ... Capila I, et al. Circulating Markers of Inflammation Persist in Children and Adults with Giant Aneurysms after Kawasaki Disease. Circulation. Genomic and Precision Medicine. PMID 30844302 DOI: 10.1161/CIRCGEN.118.002433  0.52
2018 Washburn N, Meccariello R, Duffner J, Getchell K, Holte K, Prod'homme T, Srinivasan K, Prenovitz R, Lansing J, Capila I, Kaudinya G, Manning AM, Bosques CJ. Characterization of endogenous human FcγRIII by mass spectrometry reveals site, allele and sequence specific glycosylation. Molecular & Cellular Proteomics : McP. PMID 30559323 DOI: 10.1074/mcp.RA118.001142  0.52
2017 D Alessandro JD, Garofalo K, Zhao G, Honan C, Duffner J, Capila I, Fier I, Kaundinya G, Kantor D, Ganguly T. Demonstration of Biological and Immunological Equivalence of a Generic Glatiramer Acetate. Cns & Neurological Disorders Drug Targets. PMID 28240190 DOI: 10.2174/1871527316666170223162747  0.36
2017 Yu F, Qiao J, Robblee J, Tsao D, Anderson J, Capila I. An Integrated Approach to Unique NMR Assignment of Methionine Methyl Resonances in Proteins. Analytical Chemistry. 89: 1610-1616. PMID 28208280 DOI: 10.1021/acs.analchem.6b03705  0.36
2016 Ortiz DF, Lansing JC, Rutitzky L, Kurtagic E, Prod'homme T, Choudhury A, Washburn N, Bhatnagar N, Beneduce C, Holte K, Prenovitz R, Child M, Killough J, Tyler S, Brown J, ... ... Capila I, et al. Elucidating the interplay between IgG-Fc valency and FcγR activation for the design of immune complex inhibitors. Science Translational Medicine. 8: 365ra158. PMID 27856797 DOI: 10.1126/scitranslmed.aaf9418  0.52
2016 Beccati D, Lech M, Ozug J, Gunay NS, Wang J, Sun EY, Pradines JR, Farutin V, Shriver Z, Kaundinya GV, Capila I. An integrated approach using orthogonal analytical techniques to characterize heparan sulfate structure. Glycoconjugate Journal. PMID 27771794 DOI: 10.1007/s10719-016-9734-7  0.52
2016 Sobolev O, Binda E, O'Farrell S, Lorenc A, Pradines J, Huang Y, Duffner J, Schulz R, Cason J, Zambon M, Malim MH, Peakman M, Cope A, Capila I, Kaundinya GV, et al. Corrigendum: Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events. Nature Immunology. 17: 740. PMID 27196521 DOI: 10.1038/ni0616-740b  0.52
2016 Pradines JR, Beccati D, Lech M, Ozug J, Farutin V, Huang Y, Gunay NS, Capila I. Combining measurements to estimate properties and characterization extent of complex biochemical mixtures; applications to Heparan Sulfate. Scientific Reports. 6: 24829. PMID 27112127 DOI: 10.1038/srep24829  0.64
2016 Sobolev O, Binda E, O'Farrell S, Lorenc A, Pradines J, Huang Y, Duffner J, Schulz R, Cason J, Zambon M, Malim MH, Peakman M, Cope A, Capila I, Kaundinya GV, et al. Corrigendum: Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events. Nature Immunology. 17: 469. PMID 27002849 DOI: 10.1038/ni0416-469b  0.52
2016 Sobolev O, Binda E, O'Farrell S, Lorenc A, Pradines J, Huang Y, Duffner J, Schulz R, Cason J, Zambon M, Malim MH, Peakman M, Cope A, Capila I, Kaundinya GV, et al. Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events. Nature Immunology. 17: 204-13. PMID 26726811 DOI: 10.1038/ni.3328  0.52
2015 Anderson J, Bell C, Bishop J, Capila I, Ganguly T, Glajch J, Iyer M, Kaundinya G, Lansing J, Pradines J, Prescott J, Cohen BA, Kantor D, Sachleben R. Demonstration of equivalence of a generic glatiramer acetate (Glatopa™). Journal of the Neurological Sciences. 359: 24-34. PMID 26671082 DOI: 10.1016/j.jns.2015.10.007  0.64
2015 D'Alessandro JS, Duffner J, Pradines J, Capila I, Garofalo K, Kaundinya G, Greenberg BM, Kantor D, Ganguly TC. Equivalent Gene Expression Profiles between Glatopa™ and Copaxone®. Plos One. 10: e0140299. PMID 26473741 DOI: 10.1371/journal.pone.0140299  0.64
2015 Madsen JA, Farutin V, Carbeau T, Wudyka S, Yin Y, Smith S, Anderson J, Capila I. Toward the complete characterization of host cell proteins in biotherapeutics via affinity depletions, LC-MS/MS, and multivariate analysis. Mabs. 1-10. PMID 26291024 DOI: 10.1080/19420862.2015.1082017  0.64
2015 Lech M, Capila I, Kaundinya GV. Mass spectrometric methods for the analysis of heparin and heparan sulfate. Methods in Molecular Biology (Clifton, N.J.). 1229: 119-28. PMID 25325949 DOI: 10.1007/978-1-4939-1714-3_12  0.64
2014 Roy S, El Hadri A, Richard S, Denis F, Holte K, Duffner J, Yu F, Galcheva-Gargova Z, Capila I, Schultes B, Petitou M, Kaundinya GV. Synthesis and biological evaluation of a unique heparin mimetic hexasaccharide for structure-activity relationship studies. Journal of Medicinal Chemistry. 57: 4511-20. PMID 24786387 DOI: 10.1021/jm4016069  0.64
2014 Yu F, Roy S, Arevalo E, Schaeck J, Wang J, Holte K, Duffner J, Gunay NS, Capila I, Kaundinya GV. Characterization of heparin-protein interaction by saturation transfer difference (STD) NMR. Analytical and Bioanalytical Chemistry. 406: 3079-89. PMID 24664406 DOI: 10.1007/s00216-014-7729-4  0.64
2012 Beccati D, Roy S, Lech M, Ozug J, Schaeck J, Gunay NS, Zouaoui R, Capila I, Kaundinya GV. Identification of a novel structure in heparin generated by sequential oxidative-reductive treatment. Analytical Chemistry. 84: 5091-6. PMID 22624650 DOI: 10.1021/ac3007494  0.64
2012 Ozug J, Wudyka S, Gunay NS, Beccati D, Lansing J, Wang J, Capila I, Shriver Z, Kaundinya GV. Structural elucidation of the tetrasaccharide pool in enoxaparin sodium Analytical and Bioanalytical Chemistry. 403: 2733-2744. PMID 22610547 DOI: 10.1007/s00216-012-6045-0  0.64
2012 Shriver Z, Capila I, Venkataraman G, Sasisekharan R. Heparin and heparan sulfate: analyzing structure and microheterogeneity. Handbook of Experimental Pharmacology. 159-76. PMID 22566225 DOI: 10.1007/978-3-642-23056-1_8  0.64
2011 Liu C, Dong S, Xu XJ, Yin Y, Shriver Z, Capila I, Myette J, Venkataraman G. Assessment of the quality and structural integrity of a complex glycoprotein mixture following extraction from the formulated biopharmaceutical drug product. Journal of Pharmaceutical and Biomedical Analysis. 54: 27-36. PMID 20800406 DOI: 10.1016/j.jpba.2010.07.044  0.64
2010 Beccati D, Roy S, Yu F, Gunay NS, Capila I, Lech M, Linhardt RJ, Venkataraman G. Identification of a novel structure in heparin generated by potassium permanganate oxidation. Carbohydrate Polymers. 82: 699-705. PMID 25147414 DOI: 10.1016/j.carbpol.2010.05.038  0.64
2009 Kishimoto TK, Qi YW, Long A, Capila I, Sasisekharan R, Guerrero L, Fier I, Roach J, Venkataraman G. M118--a rationally engineered low-molecular-weight heparin designed specifically for the treatment of acute coronary syndromes. Thrombosis and Haemostasis. 102: 900-6. PMID 19888526 DOI: 10.1160/TH09-02-0105  0.64
2009 Prabhakar V, Capila I, Sasisekharan R. The structural elucidation of glycosaminoglycans. Methods in Molecular Biology (Clifton, N.J.). 534: 147-56. PMID 19277554 DOI: 10.1007/978-1-59745-022-5_11  0.64
2009 Prabhakar V, Capila I, Sasisekharan R. Glycosaminoglycan characterization methodologies: probing biomolecular interactions. Methods in Molecular Biology (Clifton, N.J.). 534: 331-40. PMID 19277541 DOI: 10.1007/978-1-59745-022-5_23  0.64
2009 Prabhakar V, Capila I, Soundararajan V, Raman R, Sasisekharan R. Recombinant expression, purification, and biochemical characterization of chondroitinase ABC II from Proteus vulgaris. The Journal of Biological Chemistry. 284: 974-82. PMID 18849565 DOI: 10.1074/jbc.M806630200  0.64
2008 Guerrini M, Beccati D, Shriver Z, Naggi A, Viswanathan K, Bisio A, Capila I, Lansing JC, Guglieri S, Fraser B, Al-Hakim A, Gunay NS, Zhang Z, Robinson L, Buhse L, et al. Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events. Nature Biotechnology. 26: 669-75. PMID 18437154 DOI: 10.1038/nbt1407  0.64
2006 Prabhakar V, Capila I, Raman R, Srinivasan A, Bosques CJ, Pojasek K, Wrick MA, Sasisekharan R. The catalytic machinery of chondroitinase ABC I utilizes a calcium coordination strategy to optimally process dermatan sulfate. Biochemistry. 45: 11130-9. PMID 16964974 DOI: 10.1021/bi0605484  0.64
2005 Prabhakar V, Raman R, Capila I, Bosques CJ, Pojasek K, Sasisekharan R. Biochemical characterization of the chondroitinase ABC I active site. The Biochemical Journal. 390: 395-405. PMID 16108757 DOI: 10.1042/BJ20050532  0.64
2005 Sengupta S, Eavarone D, Capila I, Zhao G, Watson N, Kiziltepe T, Sasisekharan R. Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system. Nature. 436: 568-72. PMID 16049491 DOI: 10.1038/nature03794  0.64
2005 Prabhakar V, Capila I, Bosques CJ, Pojasek K, Sasisekharan R. Chondroitinase ABC I from Proteus vulgaris: cloning, recombinant expression and active site identification. The Biochemical Journal. 386: 103-12. PMID 15691229 DOI: 10.1042/BJ20041222  0.64
2005 Capila I, Gunay NS, Shriver Z, Venkataraman G. Methods for structural analysis of heparin and heparan sulfate Chemistry and Biology of Heparin and Heparan Sulfate. 55-77. DOI: 10.1016/B978-008044859-6/50004-6  0.64
2005 Shriver Z, Capila I, Gunay NS, Venkataraman G. Sequencing complex polysaccharides Chimica Oggi. 23: 24-26.  0.64
2004 Capila I, Sasisekharan R. Methods for Analysis of Hyaluronan and Its Fragments Chemistry and Biology of Hyaluronan. 21-40. DOI: 10.1016/B978-008044382-9/50033-9  0.64
2002 Bellin R, Capila I, Lincecum J, Park PW, Reizes O, Bernfield MR. Unlocking the secrets of syndecans: transgenic organisms as a potential key. Glycoconjugate Journal. 19: 295-304. PMID 12975608 DOI: 10.1023/A:1025352501148  0.64
2002 Capila I, Linhardt RJ. Heparin-protein interactions. Angewandte Chemie (International Ed. in English). 41: 391-412. PMID 12491369 DOI: 10.1002/1521-3773(20020201)41:3<390::AID-ANIE390>3.0.CO;2-B  0.64
2002 Garg HG, Cindhuchao N, Quinn DA, Hales CA, Thanawiroon C, Capila I, Linhardt RJ. Heparin oligosaccharide sequence and size essential for inhibition of pulmonary artery smooth muscle cell proliferation. Carbohydrate Research. 337: 2359-64. PMID 12433502 DOI: 10.1016/S0008-6215(02)00190-8  0.64
2002 Capila I, Wu Y, Rethwisch DW, Matte A, Cygler M, Linhardt RJ. Role of arginine 292 in the catalytic activity of chondroitin AC lyase from Flavobacterium heparinum. Biochimica Et Biophysica Acta. 1597: 260-70. PMID 12044904 DOI: 10.1016/S0167-4838(02)00304-7  0.64
2002 Ma Q, Dudas B, Daud A, Iqbal O, Hoppensteadt D, Jeske W, Cornelli U, Lee J, Lorens S, Mervis R, Hanin I, Capila I, Linhardt R, Fareed J. Molecular and biochemical profiling of a heparin-derived oligosaccharide, C3. Thrombosis Research. 105: 303-9. PMID 12031824 DOI: 10.1016/S0049-3848(01)00413-3  0.64
2001 Ye S, Luo Y, Lu W, Jones RB, Linhardt RJ, Capila I, Toida T, Kan M, Pelletier H, McKeehan WL. Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs. Biochemistry. 40: 14429-39. PMID 11724555 DOI: 10.1021/bi011000u  0.64
2001 Libeu CP, Lund-Katz S, Phillips MC, Wehrli S, Hernáiz MJ, Capila I, Linhardt RJ, Raffaï RL, Newhouse YM, Zhou F, Weisgraber KH. New insights into the heparan sulfate proteoglycan-binding activity of apolipoprotein E. The Journal of Biological Chemistry. 276: 39138-44. PMID 11500500 DOI: 10.1074/jbc.M104746200  0.64
2001 Capila I, Hernáiz MJ, Mo YD, Mealy TR, Campos B, Dedman JR, Linhardt RJ, Seaton BA. Annexin V--heparin oligosaccharide complex suggests heparan sulfate--mediated assembly on cell surfaces. Structure (London, England : 1993). 9: 57-64. PMID 11342135 DOI: 10.1016/S0969-2126(00)00549-9  0.64
2001 Dong J, Peters-Libeu CA, Weisgraber KH, Segelke BW, Rupp B, Capila I, Hernáiz MJ, LeBrun LA, Linhardt RJ. Interaction of the N-terminal domain of apolipoprotein E4 with heparin. Biochemistry. 40: 2826-34. PMID 11258893 DOI: 10.1021/bi002417n  0.64
2000 Hiebert LM, Wice SM, Ping T, Hileman RE, Capila I, Linhardt RJ. Tissue distribution and antithrombotic activity of unlabeled or 14C-labeled porcine intestinal mucosal heparin following administration to rats by the oral route. Canadian Journal of Physiology and Pharmacology. 78: 307-20. PMID 10772058  0.64
1999 Garg HG, Joseph PA, Thompson BT, Hales CA, Toida T, Imanari T, Capila I, Linhardt RJ. Effect of fully sulfated glycosaminoglycans on pulmonary artery smooth muscle cell proliferation. Archives of Biochemistry and Biophysics. 371: 228-33. PMID 10545209 DOI: 10.1006/abbi.1999.1456  0.64
1999 Capila I, VanderNoot VA, Mealy TR, Seaton BA, Linhardt RJ. Interaction of heparin with annexin V. Febs Letters. 446: 327-30. PMID 10100868 DOI: 10.1016/S0014-5793(99)00245-8  0.64
1998 Bazin HG, Capila I, Linhardt RJ. Conformational study of synthetic delta 4-uronate monosaccharides and glycosaminoglycan-derived disaccharides. Carbohydrate Research. 309: 135-44. PMID 9741074 DOI: 10.1016/S0008-6215(98)00118-9  0.64
1997 Wang H, Toida T, Kim YS, Capila I, Hileman RE, Bernfield M, Linhardt RJ. Glycosaminoglycans can influence fibroblast growth factor-2 mitogenicity without significant growth factor binding. Biochemical and Biophysical Research Communications. 235: 369-73. PMID 9199199 DOI: 10.1006/bbrc.1997.6789  0.64
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