Year |
Citation |
Score |
2023 |
Sunny A, James RR, Menon SR, Rayaroth S, Daniel A, Thompson NA, Tharakan B. Matrix Metalloproteinase-9 inhibitors as therapeutic drugs for traumatic brain injury. Neurochemistry International. 105642. PMID 38008261 DOI: 10.1016/j.neuint.2023.105642 |
0.492 |
|
2023 |
Alluri H, Peddaboina CS, Tharakan B. Evaluation of Tight Junction Integrity in Brain Endothelial Cells Using Confocal Microscopy. Methods in Molecular Biology (Clifton, N.J.). 2711: 257-262. PMID 37776464 DOI: 10.1007/978-1-0716-3429-5_21 |
0.809 |
|
2023 |
Alluri H, Peddaboina CS, Tharakan B. Determination of Tight Junction Integrity in Brain Endothelial Cells Based on Tight Junction Protein Expression. Methods in Molecular Biology (Clifton, N.J.). 2711: 235-240. PMID 37776462 DOI: 10.1007/978-1-0716-3429-5_19 |
0.804 |
|
2023 |
Waithe OY, Peng X, Childs EW, Tharakan B. Measurement of Transendothelial Electrical Resistance in Blood-Brain Barrier Endothelial Cells. Methods in Molecular Biology (Clifton, N.J.). 2711: 199-203. PMID 37776459 DOI: 10.1007/978-1-0716-3429-5_16 |
0.82 |
|
2023 |
Waithe OY, Peng X, Childs EW, Tharakan B. Measurement of Blood-Brain Barrier Hyperpermeability Using Evans Blue Extravasation Assay. Methods in Molecular Biology (Clifton, N.J.). 2711: 177-184. PMID 37776457 DOI: 10.1007/978-1-0716-3429-5_14 |
0.826 |
|
2023 |
Waithe OY, Shaji CA, Childs EW, Tharakan B. Determination of Blood-Brain Barrier Hyperpermeability Using Intravital Microscopy. Methods in Molecular Biology (Clifton, N.J.). 2711: 117-127. PMID 37776453 DOI: 10.1007/978-1-0716-3429-5_10 |
0.803 |
|
2022 |
Robinson BD, Isbell CL, Melge AR, Lomas AM, Shaji CA, Mohan CG, Huang JH, Tharakan B. Doxycycline prevents blood-brain barrier dysfunction and microvascular hyperpermeability after traumatic brain injury. Scientific Reports. 12: 5415. PMID 35354869 DOI: 10.1038/s41598-022-09394-4 |
0.855 |
|
2021 |
Tharakan B, Hunter FA, Muthusamy S, Randolph S, Byrd C, Rao VN, Reddy ESP, Childs EW. ETS-Related Gene Activation Preserves Adherens Junctions and Permeability in Microvascular Endothelial Cells. Shock (Augusta, Ga.). PMID 34907119 DOI: 10.1097/SHK.0000000000001899 |
0.358 |
|
2021 |
Tharakan B, Hunter FA, Childs EW. Protective Effects of FK 506 Against Hemorrhagic Shock-Induced Microvascular Hyperpermeability. Clinical and Experimental Pharmacology & Physiology. PMID 34432902 DOI: 10.1111/1440-1681.13578 |
0.31 |
|
2021 |
Huang C, Wu L, Wang J, Tharakan B, Peng X. Detecting Three-Dimensional Vascular Networks in the Mouse Embryonic Hindbrain. Methods in Molecular Biology (Clifton, N.J.). 2319: 87-92. PMID 34331246 DOI: 10.1007/978-1-0716-1480-8_10 |
0.389 |
|
2020 |
Malek AJ, Robinson BD, Hitt AR, Shaver CN, Tharakan B, Isbell CL. Doxycycline improves traumatic brain injury outcomes in a murine survival model. The Journal of Trauma and Acute Care Surgery. PMID 32467458 DOI: 10.1097/TA.0000000000002801 |
0.732 |
|
2020 |
Robinson BD, Tharakan B, Lomas A, Wiggins-Dohlvik K, Alluri H, Shaji CA, Jupiter D, Isbell CL. Exploring blood-brain barrier hyperpermeability and potential biomarkers in traumatic brain injury. Proceedings (Baylor University. Medical Center). 33: 199-204. PMID 32313461 DOI: 10.1080/08998280.2020.1727706 |
0.797 |
|
2020 |
Peng J, Lambertis A, Hunter F, Childs E, Tharakan B. Cathepsin‐B is a Mediator of Barrier Dysfunction and Hyperpermeability in Blood‐Brain Barrier Endothelial Cells The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.06905 |
0.321 |
|
2019 |
Anasooya Shaji C, Robinson BD, Yeager A, Beeram MR, Davis ML, Isbell CL, Huang JH, Tharakan B. The Tri-phasic Role of Hydrogen Peroxide in Blood-Brain Barrier Endothelial cells. Scientific Reports. 9: 133. PMID 30644421 DOI: 10.1038/S41598-018-36769-3 |
0.719 |
|
2018 |
Robinson BD, Isbell CL, Shaji CA, Kurek S, Regner JL, Tharakan B. QUETIAPINE PROTECTS THE BLOOD-BRAIN BARRIER IN TRAUMATIC BRAIN INJURY. The Journal of Trauma and Acute Care Surgery. PMID 29985239 DOI: 10.1097/Ta.0000000000002011 |
0.831 |
|
2018 |
Robinson BD, Shaji CA, Lomas A, Tharakan B. Measurement of Microvascular Endothelial Barrier Dysfunction and Hyperpermeability In Vitro. Methods in Molecular Biology (Clifton, N.J.). 1717: 237-242. PMID 29468597 DOI: 10.1007/978-1-4939-7526-6_19 |
0.811 |
|
2018 |
Wiggins-Dohlvik K, Tharakan B. A Rat Burn Injury Model for Studying Changes in Microvascular Permeability. Methods in Molecular Biology (Clifton, N.J.). 1717: 93-100. PMID 29468586 DOI: 10.1007/978-1-4939-7526-6_8 |
0.78 |
|
2018 |
Alluri H, Shaji CA, Davis ML, Tharakan B. A Mouse Controlled Cortical Impact Model of Traumatic Brain Injury for Studying Blood-Brain Barrier Dysfunctions. Methods in Molecular Biology (Clifton, N.J.). 1717: 37-52. PMID 29468582 DOI: 10.1007/978-1-4939-7526-6_4 |
0.817 |
|
2018 |
Cromer WE, Zawieja SD, Doersch KM, Stagg H, Hunter F, Tharakan B, Childs E, Zawieja DC. Burn Injury-Associated MHCII+ Immune Cell Accumulation Around Lymphatic Vessels of the Mesentery and Increased Lymphatic Endothelial Permeability Are Blocked by Doxycycline Treatment. Lymphatic Research and Biology. PMID 29359999 DOI: 10.1089/lrb.2017.0032 |
0.407 |
|
2016 |
Alluri H, Grimsley M, Anasooya Shaji C, Varghese KP, Zhang SL, Peddaboina C, Robinson B, Beeram MR, Huang JH, Tharakan B. Attenuation of Blood-Brain Barrier Breakdown and Hyperpermeability by Calpain Inhibition. The Journal of Biological Chemistry. PMID 27875293 DOI: 10.1074/Jbc.M116.735365 |
0.818 |
|
2016 |
Alluri H, Wilson RL, Anasooya Shaji C, Wiggins-Dohlvik K, Patel S, Liu Y, Peng X, Beeram MR, Davis ML, Huang JH, Tharakan B. Melatonin Preserves Blood-Brain Barrier Integrity and Permeability via Matrix Metalloproteinase-9 Inhibition. Plos One. 11: e0154427. PMID 27152411 DOI: 10.1371/Journal.Pone.0154427 |
0.835 |
|
2015 |
Tharakan B, McNeal SI, Hunter FA, Sawant DA, Smythe WR, Childs EW. RECOMBINANT BCL-XL ATTENUATES VASCULAR HYPERPERMEABILITY IN A RAT MODEL OF HEMORRHAGIC SHOCK. Cell Death Discovery. 1. PMID 27042339 DOI: 10.1038/cddiscovery.2015.42 |
0.413 |
|
2015 |
Wiggins-Dohlvik K, Stagg HW, Han MS, Alluri H, Oakley RP, Shaji CA, Davis ML, Tharakan B. Doxycycline Attenuates Lipopolysaccharide-Induced Microvascular Endothelial Cell Derangements. Shock (Augusta, Ga.). PMID 26717103 DOI: 10.1097/Shk.0000000000000556 |
0.772 |
|
2015 |
Wiggins-Dohlvik K, Oakley RP, Han MS, Stagg HW, Alluri H, Shaji CA, Davis ML, Tharakan B. Tissue inhibitor of metalloproteinase-2 inhibits burn-induced derangements and hyperpermeability in microvascular endothelial cells. American Journal of Surgery. PMID 26601648 DOI: 10.1016/J.Amjsurg.2015.08.016 |
0.761 |
|
2015 |
Sawant DA, Tharakan B, Hunter FA, Childs EW. Glycogen synthase kinase 3 inhibitor protects against microvascular hyperpermeability following hemorrhagic shock. The Journal of Trauma and Acute Care Surgery. 79: 609-16. PMID 26402535 DOI: 10.1097/TA.0000000000000807 |
0.365 |
|
2015 |
Alluri H, Anasooya Shaji C, Davis ML, Tharakan B. Oxygen-glucose deprivation and reoxygenation as an in vitro ischemia-reperfusion injury model for studying blood-brain barrier dysfunction. Journal of Visualized Experiments : Jove. e52699. PMID 25992584 DOI: 10.3791/52699 |
0.826 |
|
2015 |
Alluri H, Wiggins-Dohlvik K, Davis ML, Huang JH, Tharakan B. Blood-brain barrier dysfunction following traumatic brain injury. Metabolic Brain Disease. PMID 25624154 DOI: 10.1007/S11011-015-9651-7 |
0.83 |
|
2014 |
Sawant DA, Wilson RL, Tharakan B, Stagg HW, Hunter FA, Childs EW. Tumor necrosis factor-α-induced microvascular endothelial cell hyperpermeability: role of intrinsic apoptotic signaling. Journal of Physiology and Biochemistry. 70: 971-80. PMID 25392259 DOI: 10.1007/s13105-014-0366-8 |
0.35 |
|
2014 |
Wiggins-Dohlvik K, Merriman M, Shaji CA, Alluri H, Grimsley M, Davis ML, Smith RW, Tharakan B. Tumor necrosis factor-α disruption of brain endothelial cell barrier is mediated through matrix metalloproteinase-9. American Journal of Surgery. 208: 954-60; discussion 9. PMID 25312844 DOI: 10.1016/J.Amjsurg.2014.08.014 |
0.799 |
|
2014 |
Sawant DA, Tharakan B, Hunter FA, Childs EW. The role of intrinsic apoptotic signaling in hemorrhagic shock-induced microvascular endothelial cell barrier dysfunction. Journal of Cardiovascular Translational Research. 7: 711-8. PMID 25277298 DOI: 10.1007/s12265-014-9589-x |
0.426 |
|
2014 |
Wiggins-Dohlvik K, Han MS, Stagg HW, Alluri H, Shaji CA, Oakley RP, Davis ML, Tharakan B. Melatonin inhibits thermal injury-induced hyperpermeability in microvascular endothelial cells. The Journal of Trauma and Acute Care Surgery. 77: 899-905; discussion . PMID 25051382 DOI: 10.1097/Ta.0000000000000346 |
0.784 |
|
2014 |
Oakley R, Tharakan B. Vascular hyperpermeability and aging. Aging and Disease. 5: 114-25. PMID 24729937 DOI: 10.14336/Ad.2014.0500114 |
0.678 |
|
2014 |
Alluri H, Stagg HW, Wilson RL, Clayton RP, Sawant DA, Koneru M, Beeram MR, Davis ML, Tharakan B. Reactive oxygen species-caspase-3 relationship in mediating blood-brain barrier endothelial cell hyperpermeability following oxygen-glucose deprivation and reoxygenation. Microcirculation (New York, N.Y. : 1994). 21: 187-95. PMID 24372803 DOI: 10.1111/Micc.12110 |
0.826 |
|
2014 |
Cromer WE, Zawieja SD, Tharakan B, Childs EW, Newell MK, Zawieja DC. The effects of inflammatory cytokines on lymphatic endothelial barrier function. Angiogenesis. 17: 395-406. PMID 24141404 DOI: 10.1007/s10456-013-9393-2 |
0.399 |
|
2014 |
Wiggins-Dohlvik K, Alluir H, Shaji CA, Govande V, Beeram M, Mohammad A, Davis M, Tharakan B. 6 Critical Care Medicine. 42: A1370. DOI: 10.1097/01.Ccm.0000457539.24608.D8 |
0.747 |
|
2014 |
Wiggins-Dohlvik KC, Stagg HW, Shaji CA, Oakley RP, Alluri H, Mukhopadhyay D, Perger L, Davis ML, Tharakan B. Tissue Inhibitor of Metalloproteinases-2 (TIMP2) Inhibits Hemorrhagic Shock (HS)-Induced Vascular Hyperpermeability Journal of the American College of Surgeons. 219: S40. DOI: 10.1016/J.Jamcollsurg.2014.07.088 |
0.755 |
|
2013 |
Stagg HW, Whaley JG, Tharakan B, Hunter FA, Jupiter D, Little DC, Davis ML, Smythe WR, Childs EW. Doxycycline attenuates burn-induced microvascular hyperpermeability. The Journal of Trauma and Acute Care Surgery. 75: 1040-6; discussion 1. PMID 24256679 DOI: 10.1097/TA.0b013e3182aa9c79 |
0.476 |
|
2013 |
Sawant DA, Tharakan B, Wilson RL, Stagg HW, Hunter FA, Childs EW. Regulation of tumor necrosis factor-α-induced microvascular endothelial cell hyperpermeability by recombinant B-cell lymphoma-extra large. The Journal of Surgical Research. 184: 628-37. PMID 23731686 DOI: 10.1016/j.jss.2013.04.079 |
0.429 |
|
2013 |
Stagg HW, Bowen KA, Sawant DA, Rodriguez M, Tharakan B, Childs EW. Tumor necrosis factor-related apoptosis-inducing ligand promotes microvascular endothelial cell hyperpermeability through phosphatidylinositol 3-kinase pathway. American Journal of Surgery. 205: 419-25. PMID 23375756 DOI: 10.1016/j.amjsurg.2012.10.027 |
0.345 |
|
2013 |
Sawant DA, Tharakan B, Tobin RP, Reilly J, Hunter FA, Newell MK, Smythe WR, Childs EW. Microvascular endothelial cell hyperpermeability induced by endogenous caspase 3 activator staurosporine. The Journal of Trauma and Acute Care Surgery. 74: 516-23. PMID 23354245 DOI: 10.1097/TA.0b013e31827a0620 |
0.405 |
|
2013 |
Sawant DA, Tharakan B, Tobin RP, Stagg HW, Hunter FA, Newell MK, Smythe WR, Childs EW. Inhibition of Fas-Fas ligand interaction attenuates microvascular hyperpermeability following hemorrhagic shock. Shock (Augusta, Ga.). 39: 161-7. PMID 23324886 DOI: 10.1097/SHK.0b013e31827bba73 |
0.39 |
|
2013 |
Sawant DA, Tharakan B, Hunter FA, Childs EW. Recombinant Bcl-xL Protein Attenuates TNF-alpha Induced Microvascular Endothelial Cell Hyperpermeability Journal of Surgical Research. 179: 331. DOI: 10.1016/J.Jss.2012.10.674 |
0.334 |
|
2012 |
Tharakan B, Hellman J, Sawant DA, Tinsley JH, Parrish AR, Hunter FA, Smythe WR, Childs EW. β-Catenin dynamics in the regulation of microvascular endothelial cell hyperpermeability. Shock (Augusta, Ga.). 37: 306-11. PMID 22089197 DOI: 10.1097/SHK.0b013e318240b564 |
0.372 |
|
2012 |
Janicek A, Tharakan B, Sawant DA, Hunter FA, Childs EW. Lipopolysaccharide-Induced Endothelial Cell Hyperpermeability: Role of Mitochondrial Apoptotic Signaling Pathway Journal of Surgical Research. 172: 330. DOI: 10.1016/J.Jss.2011.11.602 |
0.33 |
|
2011 |
Sawant DA, Tharakan B, Hunter FA, Smythe WR, Childs EW. Role of β-catenin in regulating microvascular endothelial cell hyperpermeability. The Journal of Trauma. 70: 481-7; discussion 48. PMID 21307750 DOI: 10.1097/TA.0b013e31820b3ed7 |
0.393 |
|
2011 |
Sawant DA, Tharakan B, Adekanbi A, Hunter FA, Smythe WR, Childs EW. Inhibition of VE-cadherin proteasomal degradation attenuates microvascular hyperpermeability. Microcirculation (New York, N.Y. : 1994). 18: 46-55. PMID 21166925 DOI: 10.1111/j.1549-8719.2010.00067.x |
0.398 |
|
2011 |
McKenzie JR, Tharakan B, Sawant DA, Whaley JG, Hunter FA, Childs EW. Staurosporine Induces Brain Microvascular Endothelial Cell Hyperpermeability Through Intrinsic Apoptotic Signaling Pathway Journal of Surgical Research. 165: 183. DOI: 10.1016/J.Jss.2010.11.672 |
0.461 |
|
2011 |
Sawant DA, Tharakan B, Whaley JG, Hunter FA, Childs EW. β-Catenin Cleavage And Microvascular Endothelial Cell Hyperpermeability Induced By Staurosporine Journal of Surgical Research. 165: 343. DOI: 10.1016/J.Jss.2010.11.078 |
0.337 |
|
2010 |
Tharakan B, Hunter FA, Smythe WR, Childs EW. Curcumin inhibits reactive oxygen species formation and vascular hyperpermeability following haemorrhagic shock. Clinical and Experimental Pharmacology & Physiology. 37: 939-44. PMID 20528978 DOI: 10.1111/j.1440-1681.2010.05414.x |
0.391 |
|
2010 |
Childs EW, Tharakan B, Nurudeen S, Delmas TL, Hellman J, Christie T, Hunter FA, Smythe WR. Cyclosporine A--protection against microvascular hyperpermeability is calcineurin independent. American Journal of Surgery. 199: 542-8. PMID 20359571 DOI: 10.1016/j.amjsurg.2009.11.002 |
0.323 |
|
2009 |
Whaley JG, Tharakan B, Smith B, Hunter FA, Childs EW. (-)-Deprenyl inhibits thermal injury-induced apoptotic signaling and hyperpermeability in microvascular endothelial cells. Journal of Burn Care & Research : Official Publication of the American Burn Association. 30: 1018-27. PMID 19826263 DOI: 10.1097/BCR.0b013e3181bfb825 |
0.396 |
|
2009 |
Tharakan B, Holder-Haynes JG, Hunter FA, Smythe WR, Childs EW. Cyclosporine A prevents vascular hyperpermeability after hemorrhagic shock by inhibiting apoptotic signaling. The Journal of Trauma. 66: 1033-9. PMID 19359911 DOI: 10.1097/TA.0b013e31816c905f |
0.359 |
|
2009 |
Uddin MN, McLean LB, Hunter FA, Horvat D, Severson J, Tharakan B, Childs EW, Puschett JB. Vascular leak in a rat model of preeclampsia. American Journal of Nephrology. 30: 26-33. PMID 19194101 DOI: 10.1159/000193220 |
0.304 |
|
2009 |
Tharakan B, Corprew R, Hunter FA, Whaley JG, Smythe WR, Childs EW. 17beta-estradiol mediates protection against microvascular endothelial cell hyperpermeability. American Journal of Surgery. 197: 147-54. PMID 19185107 DOI: 10.1016/j.amjsurg.2008.10.003 |
0.332 |
|
2009 |
Childs EW, Tharakan B, Hunter FA. QS408. Apoptotic Signaling Regulates Vascular Hyperpermeability Following Hemorrhagic Shock Journal of Surgical Research. 151: 301. DOI: 10.1016/J.Jss.2008.11.719 |
0.324 |
|
2008 |
Tharakan B, Hunter FA, Smythe WR, Childs EW. Alpha-lipoic acid attenuates hemorrhagic shock-induced apoptotic signaling and vascular hyperpermeability. Shock (Augusta, Ga.). 30: 571-7. PMID 18923301 DOI: 10.1097/SHK.0b013e31816a7308 |
0.34 |
|
2008 |
Childs EW, Tharakan B, Hunter FA, Isong M, Liggins ND. Mitochondrial complex III is involved in proapoptotic BAK-induced microvascular endothelial cell hyperpermeability. Shock (Augusta, Ga.). 29: 636-41. PMID 18414238 DOI: 10.1097/SHK.0b013e318157f524 |
0.356 |
|
2008 |
Childs EW, Tharakan B, Byrge N, Tinsley JH, Hunter FA, Smythe WR. Angiopoietin-1 inhibits intrinsic apoptotic signaling and vascular hyperpermeability following hemorrhagic shock. American Journal of Physiology. Heart and Circulatory Physiology. 294: H2285-95. PMID 18344375 DOI: 10.1152/ajpheart.01361.2007 |
0.38 |
|
2008 |
Tharakan B, Holder-Haynes JG, Hunter FA, Childs EW. Alpha lipoic acid attenuates microvascular endothelial cell hyperpermeability by inhibiting the intrinsic apoptotic signaling. American Journal of Surgery. 195: 174-8. PMID 18096126 DOI: 10.1016/j.amjsurg.2007.09.028 |
0.361 |
|
2007 |
Dhanasekaran M, Tharakan B, Holcomb LA, Hitt AR, Young KA, Manyam BV. Neuroprotective mechanisms of ayurvedic antidementia botanical Bacopa monniera. Phytotherapy Research : Ptr. 21: 965-9. PMID 17604373 DOI: 10.1002/ptr.2195 |
0.306 |
|
2007 |
Childs EW, Tharakan B, Hunter FA, Tinsley JH, Cao X. Apoptotic signaling induces hyperpermeability following hemorrhagic shock. American Journal of Physiology. Heart and Circulatory Physiology. 292: H3179-89. PMID 17307990 DOI: 10.1152/ajpheart.01337.2006 |
0.333 |
|
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