Wayne W. Poon, Ph.D. - Publications

Affiliations: 
2001 University of California, Los Angeles, Los Angeles, CA 
Area:
Biochemistry, Chemical Biology, Proteomics and Bioinformatics, Systems Biology and Biological Regulation, Metabolism, Aging and Development

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Poon WW, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.44
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Poon WW, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/ng.3916  0.44
2014 Pensalfini A, Albay R, Rasool S, Wu JW, Hatami A, Arai H, Margol L, Milton S, Poon WW, Corrada MM, Kawas CH, Glabe CG. Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques. Neurobiology of Disease. 71: 53-61. PMID 25092575 DOI: 10.1016/j.nbd.2014.07.011  0.72
2014 Nelson PT, Estus S, Abner EL, Parikh I, Malik M, Neltner JH, Ighodaro E, Wang WX, Wilfred BR, Wang LS, Kukull WA, Nandakumar K, Farman ML, Poon WW, Corrada MM, et al. ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta Neuropathologica. 127: 825-43. PMID 24770881 DOI: 10.1007/s00401-014-1282-2  0.72
2014 Rohn TT, Day RJ, Sheffield CB, Rajic AJ, Poon WW. Apolipoprotein E pathology in vascular dementia. International Journal of Clinical and Experimental Pathology. 7: 938-47. PMID 24696712  0.72
2013 Rohn TT, Day RJ, Catlin LW, Brown RJ, Rajic AJ, Poon WW. Immunolocalization of an amino-terminal fragment of apolipoprotein E in the Pick's disease brain. Plos One. 8: e80180. PMID 24312462 DOI: 10.1371/journal.pone.0080180  0.72
2013 Poon WW, Carlos AJ, Aguilar BL, Berchtold NC, Kawano CK, Zograbyan V, Yaopruke T, Shelanski M, Cotman CW. β-Amyloid (Aβ) oligomers impair brain-derived neurotrophic factor retrograde trafficking by down-regulating ubiquitin C-terminal hydrolase, UCH-L1. The Journal of Biological Chemistry. 288: 16937-48. PMID 23599427 DOI: 10.1074/jbc.M113.463711  0.72
2013 Tai LM, Bilousova T, Jungbauer L, Roeske SK, Youmans KL, Yu C, Poon WW, Cornwell LB, Miller CA, Vinters HV, Van Eldik LJ, Fardo DW, Estus S, Bu G, Gylys KH, et al. Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples. The Journal of Biological Chemistry. 288: 5914-26. PMID 23293020 DOI: 10.1074/jbc.M112.442103  0.72
2013 Rohn TT, Catlin LW, Poon WW. Caspase-cleaved glial fibrillary acidic protein within cerebellar white matter of the Alzheimer's disease brain. International Journal of Clinical and Experimental Pathology. 6: 41-8. PMID 23236541  0.72
2012 Kim HJ, Park JW, Byun JH, Poon WW, Cotman CW, Fowlkes CC, Jeon NL. Quantitative analysis of axonal transport by using compartmentalized and surface micropatterned culture of neurons. Acs Chemical Neuroscience. 3: 433-8. PMID 24358503 DOI: 10.1021/cn3000026  0.72
2012 Henkins KM, Sokolow S, Miller CA, Vinters HV, Poon WW, Cornwell LB, Saing T, Gylys KH. Extensive p-tau pathology and SDS-stable p-tau oligomers in Alzheimer's cortical synapses. Brain Pathology (Zurich, Switzerland). 22: 826-33. PMID 22486774 DOI: 10.1111/j.1750-3639.2012.00598.x  0.72
2012 Arold S, Sullivan P, Bilousova T, Teng E, Miller CA, Poon WW, Vinters HV, Cornwell LB, Saing T, Cole GM, Gylys KH. Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex. Acta Neuropathologica. 123: 39-52. PMID 22020632 DOI: 10.1007/s00401-011-0892-1  0.72
2012 Sokolow S, Luu SH, Nandy K, Miller CA, Vinters HV, Poon WW, Gylys KH. Preferential accumulation of amyloid-beta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex. Neurobiology of Disease. 45: 381-7. PMID 21914482 DOI: 10.1016/j.nbd.2011.08.027  0.72
2012 Sokolow S, Henkins KM, Bilousova T, Miller CA, Vinters HV, Poon W, Cole GM, Gylys KH. AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56-kDa assembly. Neurobiology of Aging. 33: 1545-55. PMID 21741125 DOI: 10.1016/j.neurobiolaging.2011.05.011  0.72
2011 Poon WW, Blurton-Jones M, Tu CH, Feinberg LM, Chabrier MA, Harris JW, Jeon NL, Cotman CW. β-Amyloid impairs axonal BDNF retrograde trafficking. Neurobiology of Aging. 32: 821-33. PMID 19540623 DOI: 10.1016/j.neurobiolaging.2009.05.012  0.72
2009 Rohn TT, Kokoulina P, Eaton CR, Poon WW. Caspase activation in transgenic mice with Alzheimer-like pathology: results from a pilot study utilizing the caspase inhibitor, Q-VD-OPh. International Journal of Clinical and Experimental Medicine. 2: 300-8. PMID 20057974  0.72
2009 Blurton-Jones M, Kitazawa M, Martinez-Coria H, Castello NA, Müller FJ, Loring JF, Yamasaki TR, Poon WW, Green KN, LaFerla FM. Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 106: 13594-9. PMID 19633196 DOI: 10.1073/pnas.0901402106  0.72
2008 Nichol KE, Poon WW, Parachikova AI, Cribbs DH, Glabe CG, Cotman CW. Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid. Journal of Neuroinflammation. 5: 13. PMID 18400101 DOI: 10.1186/1742-2094-5-13  0.72
2005 Marbois B, Gin P, Faull KF, Poon WW, Lee PT, Strahan J, Shepherd JN, Clarke CF. Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q. The Journal of Biological Chemistry. 280: 20231-8. PMID 15792955 DOI: 10.1074/jbc.M501315200  0.52
2005 Cotman CW, Poon WW, Rissman RA, Blurton-Jones M. The role of caspase cleavage of tau in Alzheimer disease neuropathology. Journal of Neuropathology and Experimental Neurology. 64: 104-12. PMID 15751224  0.72
2005 Head E, Moffat K, Das P, Sarsoza F, Poon WW, Landsberg G, Cotman CW, Murphy MP. Beta-amyloid deposition and tau phosphorylation in clinically characterized aged cats. Neurobiology of Aging. 26: 749-63. PMID 15708450 DOI: 10.1016/j.neurobiolaging.2004.06.015  0.72
2004 Cribbs DH, Poon WW, Rissman RA, Blurton-Jones M. Caspase-mediated degeneration in Alzheimer's disease. The American Journal of Pathology. 165: 353-5. PMID 15277211 DOI: 10.1016/S0002-9440(10)63302-0  0.72
2004 Rissman RA, Poon WW, Blurton-Jones M, Oddo S, Torp R, Vitek MP, LaFerla FM, Rohn TT, Cotman CW. Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. The Journal of Clinical Investigation. 114: 121-30. PMID 15232619 DOI: 10.1172/JCI20640  0.72
2000 Poon WW, Davis DE, Ha HT, Jonassen T, Rather PN, Clarke CF. Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis. Journal of Bacteriology. 182: 5139-46. PMID 10960098 DOI: 10.1128/JB.182.18.5139-5146.2000  0.72
1999 Poon WW, Barkovich RJ, Hsu AY, Frankel A, Lee PT, Shepherd JN, Myles DC, Clarke CF. Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis. The Journal of Biological Chemistry. 274: 21665-72. PMID 10419476 DOI: 10.1074/jbc.274.31.21665  0.72
1997 Poon WW, Do TQ, Marbois BN, Clarke CF. Sensitivity to treatment with polyunsaturated fatty acids is a general characteristic of the ubiquinone-deficient yeast coq mutants. Molecular Aspects of Medicine. 18: S121-7. PMID 9266513 DOI: 10.1016/S0098-2997(97)00004-6  0.72
1996 Hsu AY, Poon WW, Shepherd JA, Myles DC, Clarke CF. Complementation of coq3 mutant yeast by mitochondrial targeting of the Escherichia coli UbiG polypeptide: evidence that UbiG catalyzes both O-methylation steps in ubiquinone biosynthesis. Biochemistry. 35: 9797-806. PMID 8703953 DOI: 10.1021/bi9602932  0.72
1996 Shepherd JA, Poon WW, Myles DC, Clarke CF. The biosynthesis of ubiquinone: Synthesis and enzymatic modification of biosynthetic precursors Tetrahedron Letters. 37: 2395-2398. DOI: 10.1016/0040-4039(96)00324-3  0.72
1995 Poon WW, Marbois BN, Faull KF, Clarke CF. 3-Hexaprenyl-4-hydroxybenzoic acid forms a predominant intermediate pool in ubiquinone biosynthesis in Saccharomyces cerevisiae. Archives of Biochemistry and Biophysics. 320: 305-14. PMID 7625838 DOI: 10.1016/0003-9861(95)90014-4  0.72
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