Margaret A. Brimble - Publications

Affiliations: 
Chemistry The University of Auckland, Auckland, Auckland, New Zealand 

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Year Citation  Score
2021 Tong JTW, Harris PWR, Brimble MA, Kavianinia I. An Insight into FDA Approved Antibody-Drug Conjugates for Cancer Therapy. Molecules (Basel, Switzerland). 26. PMID 34641391 DOI: 10.3390/molecules26195847  1
2021 Lee KL, Aitken JF, Li X, Montgomery K, Hsu HL, Williams GM, Brimble MA, Cooper GJS. Vesiculin derived from IGF-II drives increased islet cell mass in a mouse model of pre-diabetes. Islets. 1-9. PMID 34632959 DOI: 10.1080/19382014.2021.1982326  1
2021 Tasma Z, Siow A, Harris PWR, Brimble MA, Hay DL, Walker CS. Characterisation of agonist signalling profiles and agonist-dependent antagonism at PACAP-responsive receptors: implications for drug discovery. British Journal of Pharmacology. PMID 34612509 DOI: 10.1111/bph.15700  1
2021 Swain JA, Walker SR, Calvert MB, Brimble MA. The tryptophan connection: cyclic peptide natural products linked the tryptophan side chain. Natural Product Reports. PMID 34581375 DOI: 10.1039/d1np00043h  1
2021 Ding XB, Aitken HRM, Pearl ES, Furkert DP, Brimble MA. Synthesis of the C4-C16 Polyketide Fragment of Portimines A and B. The Journal of Organic Chemistry. PMID 34469687 DOI: 10.1021/acs.joc.1c01463  1
2021 Kovalenko N, Howard GK, Swain JA, Hermant Y, Cameron AJ, Cook GM, Ferguson SA, Stubbing LA, Harris PWR, Brimble MA. A Concise Synthetic Strategy Towards the Novel Calcium-dependent Lipopeptide Antibiotic, Malacidin A and Analogues. Frontiers in Chemistry. 9: 687875. PMID 34422759 DOI: 10.3389/fchem.2021.687875  1
2021 Yim V, Hermant YO, Harris PWR, Brimble MA. Synthesis of Lipopeptides by CLipPA Chemistry. Methods in Molecular Biology (Clifton, N.J.). 2355: 253-263. PMID 34386963 DOI: 10.1007/978-1-0716-1617-8_19  1
2021 Davison EK, Shepperson CE, Wilson ZE, Brimble MA. Scalable Biomimetic Syntheses of Paeciloketal B, 1--Paeciloketal B, and Bysspectin A. Journal of Natural Products. PMID 34351758 DOI: 10.1021/acs.jnatprod.1c00502  1
2021 Hermant Y, Palpal-Latoc D, Kovalenko N, Cameron AJ, Brimble MA, Harris PWR. The Total Chemical Synthesis and Biological Evaluation of the Cationic Antimicrobial Peptides, Laterocidine and Brevicidine. Journal of Natural Products. PMID 34338512 DOI: 10.1021/acs.jnatprod.1c00222  1
2021 Garelja ML, Bower RL, Brimble MA, Chand S, Harris PWR, Jamaluddin MA, Petersen J, Siow A, Walker CS, Hay DL. Pharmacological characterisation of mouse calcitonin and calcitonin receptor-like receptors reveals differences compared to human receptors. British Journal of Pharmacology. PMID 34289083 DOI: 10.1111/bph.15628  0.01
2021 Garelja ML, Bower RL, Brimble MA, Chand S, Harris PWR, Jamaluddin MA, Petersen J, Siow A, Walker CS, Hay DL. Pharmacological characterisation of mouse calcitonin and calcitonin receptor-like receptors reveals differences compared to human receptors. British Journal of Pharmacology. PMID 34289083 DOI: 10.1111/bph.15628  1
2021 Van Zuylen EM, Ferguson SA, Hughes A, Rennison D, Brimble MA, Cook GM. Disruption of Metallostasis in the Anaerobic Human Pathogen by the Zinc Ionophore PBT2. Acs Infectious Diseases. PMID 34259502 DOI: 10.1021/acsinfecdis.0c00887  1
2021 Rani A, De Leon-Rodriguez LM, Kavianinia I, McGillivray DJ, Williams DE, Brimble MA. Synthesis and characterization of mono -lipidated peptide hydrogels: a platform for the preparation of reactive oxygen species responsive materials. Organic & Biomolecular Chemistry. 19: 3665-3677. PMID 33908574 DOI: 10.1039/d1ob00355k  1
2021 Lawrence SA, Robinson HF, Furkert DP, Brimble MA, Gerth ML. Screening a Natural Product-Inspired Library for Anti- Activities. Molecules (Basel, Switzerland). 26. PMID 33804938 DOI: 10.3390/molecules26071819  1
2021 Hanna CC, Hermant YO, Harris PWR, Brimble MA. Discovery, Synthesis, and Optimization of Peptide-Based Antibiotics. Accounts of Chemical Research. PMID 33750106 DOI: 10.1021/acs.accounts.0c00841  1
2021 Ahangarpour M, Kavianinia I, Harris PWR, Brimble MA. Photo-induced radical thiol-ene chemistry: a versatile toolbox for peptide-based drug design. Chemical Society Reviews. PMID 33404559 DOI: 10.1039/d0cs00354a  1
2020 Yim V, Kavianinia I, Knottenbelt MK, Ferguson SA, Cook GM, Swift S, Chakraborty A, Allison JR, Cameron AJ, Harris PWR, Brimble MA. "CLipP"ing on lipids to generate antibacterial lipopeptides. Chemical Science. 11: 5759-5765. PMID 34094080 DOI: 10.1039/d0sc01814g  1
2020 Yang SH, Clemett CA, Brimble MA, O'Carroll SJ, Harris PWR. Synthesis and biological evaluation of -lipidated lipopeptides of a connexin 43 channel inhibitory peptide. Rsc Medicinal Chemistry. 11: 1041-1047. PMID 33479696 DOI: 10.1039/d0md00172d  1
2020 Brimble MA, Grant P. seco-Labdanes: a Study of Terpenoid Structural Diversity Resulting from Biosynthetic C-C Bond Cleavage. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 33289161 DOI: 10.1002/chem.202004574  1
2020 Gao L, Wang W, Wang X, Yang F, Xie L, Shen J, Brimble MA, Xiao Q, Yao SQ. Fluorescent probes for bioimaging of potential biomarkers in Parkinson's disease. Chemical Society Reviews. PMID 33284303 DOI: 10.1039/d0cs00115e  0.01
2020 Davison EK, McGowan JE, Li FF, Harper AD, Jeong JY, Mros S, Harbison-Price N, Van Zuylen EM, Knottenbelt MK, Heikal A, Ferguson SA, McConnell MA, Cook GM, Krittaphol W, Walker GF, ... Brimble MA, et al. C-2 derivatized 8-sulfonamidoquinolines as antibacterial compounds. Bioorganic & Medicinal Chemistry. 115837. PMID 33223463 DOI: 10.1016/j.bmc.2020.115837  1
2020 Wang Y, Yang SH, Brimble MA, Harris PWR. Recent Progress in the Synthesis of Homogeneous Erythropoietin (EPO) Glycoforms. Chembiochem : a European Journal of Chemical Biology. PMID 33210450 DOI: 10.1002/Cbic.202000347  1
2020 Zhang W, Kaplan AR, Davison EK, Freeman JL, Brimble MA, Wuest WM. Building -bicyclo[4.4.0]decanes/decenes in complex multifunctional frameworks: the case for antibiotic development. Natural Product Reports. PMID 33206093 DOI: 10.1039/d0np00052c  1
2020 Shepperson OA, Cameron AJ, Wang CJ, Harris PWR, Taylor JA, Brimble MA. Thiol-ene enabled preparation of -lipidated anti-HBV peptides. Organic & Biomolecular Chemistry. PMID 33185215 DOI: 10.1039/d0ob01997f  1
2020 Grant PS, Furkert DP, Brimble MA. Total Synthesis of (±)-Leonuketal. Organic Letters. PMID 33086011 DOI: 10.1021/acs.orglett.0c03364  1
2020 Siow A, Kowalczyk R, Brimble MA, Harris PWR. Evolution of Peptide-Based Prostate-Specific Membrane Antigen (PSMA) Inhibitors: An Approach to Novel Prostate Cancer Therapeutics. Current Medicinal Chemistry. PMID 33023429 DOI: 10.2174/0929867327666201006153847  1
2020 Ko KY, Wilson ZE, Brimble MA. The synthesis and bioactivity of the marine macrolide callyspongiolide. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32989817 DOI: 10.1002/chem.202003898  0.01
2020 Dissanayake SSM, Ekambaram M, Li KC, Harris PWR, Brimble MA. Identification of Key Functional Motifs of Native Amelogenin Protein for Dental Enamel Remineralisation. Molecules (Basel, Switzerland). 25. PMID 32937944 DOI: 10.3390/Molecules25184214  1
2020 Yim VV, Cameron AJ, Kavianinia I, Harris PWR, Brimble MA. Thiol-ene Enabled Chemical Synthesis of Truncated -Lipidated Teixobactin Analogs. Frontiers in Chemistry. 8: 568. PMID 32850619 DOI: 10.3389/Fchem.2020.00568  1
2020 Drummond GJ, Grant PS, Brimble MA. ent-Atisane diterpenoids: isolation, structure and bioactivity. Natural Product Reports. PMID 32716458 DOI: 10.1039/D0Np00039F  1
2020 Brimble MA, Cameron AJ, Harris PWR. On-resin Preparation of Allenamidyl Peptides: a Versatile Chemoselective Conjugation and Intramolecular Cyclisation Tool. Angewandte Chemie (International Ed. in English). PMID 32700356 DOI: 10.1002/Anie.202004656  1
2020 Rani A, Kavianinia I, De Leon-Rodriguez LM, McGillivray DJ, Williams DE, Brimble MA. Nanoribbon Self-assembly and Hydrogel Formation from an N-Octanoyl Octapeptide Derived from the Antiparallel β-Interface of a Protein Homotetramer. Acta Biomaterialia. PMID 32682054 DOI: 10.1016/J.Actbio.2020.07.023  1
2020 Wilson ZE, Brimble MA. Molecules derived from the extremes of life: a decade later. Natural Product Reports. PMID 32672280 DOI: 10.1039/D0Np00021C  1
2020 Li FF, Stubbing LA, Kavianinia I, Abbattista MR, Harris PWR, Smaill JB, Patterson AV, Brimble MA. Synthesis and antiproliferative activity of C- and N-terminal analogues of culicinin D. Bioorganic & Medicinal Chemistry Letters. 30: 127331. PMID 32631536 DOI: 10.1016/J.Bmcl.2020.127331  1
2020 Davison EK, Freeman JL, Zhang W, Wuest WM, Furkert DP, Brimble MA. Asymmetric Total Synthesis of the Naturally Occurring Antibiotic Anthracimycin. Organic Letters. PMID 32598151 DOI: 10.1021/Acs.Orglett.0C01913  1
2020 Rani A, Kavianinia I, Hume P, De Leon-Rodriguez LM, Kihara S, Williams DE, McGillivray DJ, Plank NOV, Gerrard J, Hodgkiss JM, Brimble MA. Directed self-assembly of peptide-diketopyrrolopyrrole conjugates - a platform for bio-organic thin film preparation. Soft Matter. PMID 32588868 DOI: 10.1039/D0Sm01071E  1
2020 Lu BL, Williams GM, Brimble MA. TLR2 agonists and their structure-activity relationships. Organic & Biomolecular Chemistry. PMID 32582902 DOI: 10.1039/D0Ob00942C  1
2020 Tong JTW, Kavianinia I, Ferguson SA, Cook GM, Harris PWR, Brimble MA. Synthesis of paenipeptin C' analogues employing solution-phase CLipPA chemistry. Organic & Biomolecular Chemistry. PMID 32469029 DOI: 10.1039/D0Ob00950D  1
2020 Cho CAH, Liang C, Perera J, Brimble MA, Swift S, Jin J. Guanidinylated Amphiphilic Polycarbonates with Enhanced Antimicrobial Activity by Extending the Length of the Spacer Arm and Micelle Self-Assembly. Macromolecular Bioscience. e2000065. PMID 32459065 DOI: 10.1002/Mabi.202000065  1
2020 Shimabukuro Okuda L, Tallada Iborra R, Ramos Pinto P, Fabres Machado U, Corrêa-Giannella ML, Pickford R, Woods T, Brimble MA, Rye KA, Passarelli M. Advanced Glycated apoA-IV Loses Its Ability to Prevent the LPS-Induced Reduction in Cholesterol Efflux-Related Gene Expression in Macrophages. Mediators of Inflammation. 2020: 6515401. PMID 32410861 DOI: 10.1155/2020/6515401  1
2020 Lin B, Daniels BJ, Middleditch MJ, Furkert DP, Brimble MA, Bong J, Stephens JM, Loomes KM. Utility of the Compound Lepteridine as a Chemical Marker for Manuka Honey Authenticity. Acs Omega. 5: 8858-8866. PMID 32337448 DOI: 10.1021/acsomega.0c00486  1
2020 Cebon JS, Gore M, Thompson JF, Davis ID, McArthur GA, Walpole E, Smithers M, Cerundolo V, Dunbar PR, MacGregor D, Fisher C, Millward M, Nathan P, Findlay MPN, Hersey P, ... ... Brimble M, et al. Results of a randomized, double-blind phase II clinical trial of NY-ESO-1 vaccine with ISCOMATRIX adjuvant versus ISCOMATRIX alone in participants with high-risk resected melanoma. Journal For Immunotherapy of Cancer. 8. PMID 32317292 DOI: 10.1136/Jitc-2019-000410  1
2020 Gingell JJ, Rees TA, Hendrikse ER, Siow A, Rennison D, Scotter J, Harris PWR, Brimble MA, Walker CS, Hay DL. Distinct Patterns of Internalization of Different Calcitonin Gene-Related Peptide Receptors. Acs Pharmacology & Translational Science. 3: 296-304. PMID 32296769 DOI: 10.1021/acsptsci.9b00089  1
2020 Garelja ML, Au M, Brimble MA, Gingell JJ, Hendrikse ER, Lovell A, Prodan N, Sexton PM, Siow A, Walker CS, Watkins HA, Williams GM, Wootten D, Yang SH, Harris PWR, et al. Molecular Mechanisms of Class B GPCR Activation: Insights from Adrenomedullin Receptors. Acs Pharmacology & Translational Science. 3: 246-262. PMID 32296766 DOI: 10.1021/acsptsci.9b00083  1
2020 Calvert MB, Furkert DP, Cooper CB, Brimble MA. Synthetic approaches towards bedaquiline and its derivatives. Bioorganic & Medicinal Chemistry Letters. 127172. PMID 32291133 DOI: 10.1016/J.Bmcl.2020.127172  1
2020 Brimble MA, Paterson D, Flanagan J, Shepherd P, Harris P. Variable-length Ester-based Staples for α-Helical Peptides Using A Double Thiol-ene Reaction. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32232881 DOI: 10.1002/Chem.202001478  1
2020 Kavianinia I, Stubbing LA, Abbattista MR, Harris PWR, Smaill JB, Patterson AV, Brimble MA. Alanine scan-guided synthesis and biological evaluation of analogues of culicinin D, a potent anticancer peptaibol. Bioorganic & Medicinal Chemistry Letters. 127135. PMID 32229061 DOI: 10.1016/J.Bmcl.2020.127135  1
2020 McGowan JE, Harper AD, Davison EK, Jeong JY, Mros S, Harbison-Price N, Van Zuylen EM, Knottenbelt MK, Heikal A, Ferguson SA, McConnell MA, Cook GM, Krittaphol W, Walker GF, Brimble MA, et al. Substituted sulfonamide bioisosteres of 8-hydroxyquinoline as zinc-dependent antibacterial compounds. Bioorganic & Medicinal Chemistry Letters. 127110. PMID 32229060 DOI: 10.1016/J.Bmcl.2020.127110  1
2020 Lu BL, Loomes KM, Hay DL, Harris PWR, Brimble MA. Synthesis of isotopically labelled αCGRP and its lipidated analogue. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 32212343 DOI: 10.1002/Jlcr.3838  1
2020 Harbison-Price N, Ferguson SA, Heikal A, Taiaroa G, Hards K, Nakatani Y, Rennison D, Brimble MA, El-Deeb IM, Bohlmann L, McDevitt CA, von Itzstein M, Walker MJ, Cook GM. Multiple Bactericidal Mechanisms of the Zinc Ionophore PBT2. Msphere. 5. PMID 32188750 DOI: 10.1128/mSphere.00157-20  1
2020 Yim VV, Kavianinia I, Cameron AJ, Harris PWR, Brimble MA. Direct synthesis of cyclic lipopeptides using intramolecular native chemical ligation and thiol-ene CLipPA chemistry. Organic & Biomolecular Chemistry. PMID 32048704 DOI: 10.1039/D0Ob00203H  1
2020 Choi H, Shirley HJ, Aitken HRM, Schulte T, Söhnel T, Hume PA, Brimble MA, Furkert DP. Intermolecular Diels-Alder Cycloaddition/Cross-Coupling Sequences of 2-Bromo-1,3-butadienes. Organic Letters. PMID 31990192 DOI: 10.1021/Acs.Orglett.9B04567  1
2020 Hermant YO, Cameron AJ, Harris PWR, Brimble MA. Synthesis of Antimicrobial Lipopeptides Using the "CLipPA" Thiol-Ene Reaction. Methods in Molecular Biology (Clifton, N.J.). 2103: 263-274. PMID 31879932 DOI: 10.1007/978-1-0716-0227-0_18  1
2020 Rees TA, Gingell J, Siow A, Harris P, Brimble M, Hay D, Walker C. Differential internalisation of the CGRP and AMY 1 receptor The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02530  1
2020 Freeman JL, Li FF, Furkert DP, Brimble MA. Synthetic Studies Towards Spirocyclic Imine Marine Toxins Using N-Acyl Iminium Ions as Dienophiles in Diels–Alder Reactions Synlett. 31: 657-671. DOI: 10.1055/S-0039-1691593  0.01
2020 Aitken HRM, Brimble MA, Furkert DP. A Catalytic Asymmetric Ene Reaction for Direct Preparation of α-Hydroxy 1,4-Diketones as Intermediates in Natural Product Synthesis Synlett. 31: 687-690. DOI: 10.1055/S-0037-1610748  0.01
2020 Yim V, Kavianinia I, Knottenbelt MK, Ferguson SA, Cook GM, Swift S, Chakraborty A, Allison JR, Cameron AJ, Harris PWR, Brimble MA. “CLipP”ing on lipids to generate antibacterial lipopeptides Chemical Science. 11: 5759-5765. DOI: 10.1039/D0Sc01814G  1
2020 De Leon-Rodriguez LM, Park Y, Naot D, Musson DS, Cornish J, Brimble MA. Design, characterization and evaluation of β-hairpin peptide hydrogels as a support for osteoblast cell growth and bovine lactoferrin delivery Rsc Advances. 10: 18222-18230. DOI: 10.1039/D0Ra03011B  0.04
2020 Gaar J, Naffa R, Brimble M. Enzymatic and non-enzymatic crosslinks found in collagen and elastin and their chemical synthesis Organic Chemistry Frontiers. 7: 2789-2814. DOI: 10.1039/D0Qo00624F  1
2020 Stubbing LA, Kaur H, Feng SX, Aalderink M, Dragunow M, Brimble MA. Synthesis of peptide homo‐ and heterodimers as potential mimics of platelet‐derived growth factor BB Peptide Science. 112. DOI: 10.1002/Pep2.24150  0.01
2020 Yang S, Hermant YOJ, Harris PWR, Brimble MA. Replacement of the Acrid tert‐Butylthiol and an Improved Isolation Protocol for Cysteine Lipidation on a Peptide or Amino Acid (CLipPA) European Journal of Organic Chemistry. 2020: 944-947. DOI: 10.1002/Ejoc.201901696  1
2020 Brimble MA, Ko K, Wilson ZE, Furkert DP. A Ring Closing Metathesis Approach to the Formal Synthesis of (+)‐Callyspongiolide Chemcatchem. DOI: 10.1002/Cctc.202001139  1
2019 Cameron AJ, Davison EK, An C, Stubbing LA, Dunbar PR, Harris PWR, Brimble MA. Synthesis and SAR analysis of lipovelutibols B and D and their lipid analogues. The Journal of Organic Chemistry. PMID 31755712 DOI: 10.1021/Acs.Joc.9B02348  1
2019 Grant PS, Kahlcke N, Govindpani K, Hunter M, MacDonald C, Brimble MA, Glass M, Furkert DP. Divalent cannabinoid-1 receptor ligands: A linker attachment point survey of SR141716A for development of high-affinity CB1R molecular probes. Bioorganic & Medicinal Chemistry Letters. 126644. PMID 31564385 DOI: 10.1016/J.Bmcl.2019.126644  1
2019 Ferguson SA, Menorca A, Van Zuylen EM, Cheung CY, McConnell MA, Rennison D, Brimble MA, Bodle K, McDougall S, Cook GM, Heikal A. Microtiter Screening Reveals Oxygen-Dependent Antimicrobial Activity of Natural Products Against Mastitis-Causing Bacteria. Frontiers in Microbiology. 10: 1995. PMID 31555233 DOI: 10.3389/Fmicb.2019.01995  1
2019 Gillard RM, Brimble MA. Benzannulated spiroketal natural products: isolation, biological activity, biosynthesis, and total synthesis. Organic & Biomolecular Chemistry. 17: 8272-8307. PMID 31478048 DOI: 10.1039/C9Ob01598A  0.01
2019 Brimble MA, Xu B, Hermant Y, Yang SH, Harris P. A versatile Boc solid phase synthesis of daptomycin and analogues using site specific, on-resin ozonolysis to install the kynurenine residue. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31429133 DOI: 10.1002/Chem.201903725  1
2019 Lu B, Williams GM, Verdon D, Dunbar PR, Brimble MA. Synthesis and evaluation of novel TLR2 agonists as potential adjuvants for cancer vaccines. Journal of Medicinal Chemistry. PMID 31418565 DOI: 10.1021/Acs.Jmedchem.9B01044  1
2019 Jeong JY, Sperry J, Brimble MA. Synthesis of the Tetracyclic Cores of the Integrastatins, Epicoccolide A and Epicocconigrone A. The Journal of Organic Chemistry. PMID 31416308 DOI: 10.1021/Acs.Joc.9B01796  1
2019 Brimble MA. Organic Synthesis: Where to from Now? A Personal Perspective from Down Under. Organic Letters. 21: 5773-5774. PMID 31370400 DOI: 10.1021/Acs.Orglett.9B02271  0.01
2019 Kasim JK, Kavianinia I, Harris PWR, Brimble MA. Three Decades of Amyloid Beta Synthesis: Challenges and Advances. Frontiers in Chemistry. 7: 472. PMID 31334219 DOI: 10.3389/Fchem.2019.00472  1
2019 Musa H, Hendrikse E, Brimble MA, Garelja M, Watkins HA, Harris PWR, Hay DL. Pharmacological characterization and investigation of N-terminal loop amino acids of adrenomedullin 2 that are important for receptor activation. Biochemistry. PMID 31328503 DOI: 10.1021/Acs.Biochem.9B00571  1
2019 Daniels BJ, Li FF, Furkert DP, Brimble MA. Naturally Occurring Lumazines. Journal of Natural Products. PMID 31317731 DOI: 10.1021/Acs.Jnatprod.9B00351  1
2019 Brimble MA, Ding X, Furkert D. Highly Diastereoselective Synthesis of Syn-1,3-Dihydroxyketone Motifs from Propargylic Alcohols via Unusual Spiroepoxide Intermediates. Angewandte Chemie (International Ed. in English). PMID 31218800 DOI: 10.1002/Anie.201905736  1
2019 Davison EK, Cameron AJ, Harris PWR, Brimble MA. Synthesis of endolides A and B: naturally occurring -methylated cyclic tetrapeptides. Medchemcomm. 10: 693-698. PMID 31191859 DOI: 10.1039/C9Md00050J  1
2019 Saponara S, Fusi F, Spiga O, Trezza A, Hopkins B, Brimble MA, Rennison D, Bova S. The Selective Rat Toxicant Norbormide Blocks K Channels in Smooth Muscle Cells But Not in Insulin-Secreting Cells. Frontiers in Pharmacology. 10: 598. PMID 31191321 DOI: 10.3389/Fphar.2019.00598  1
2019 Stubbing LA, Kavianinia I, Abbattista MR, Harris PWR, Smaill JB, Patterson AV, Brimble MA. Synthesis and antiproliferative activity of culicinin D analogues containing simplified AHMOD-based residues. European Journal of Medicinal Chemistry. 177: 235-246. PMID 31152989 DOI: 10.1016/J.Ejmech.2019.05.052  1
2019 Lee KL, Aitken JF, Hsu HL, Williams GM, Brimble MA, Cooper GJS. Glucoregulatory activity of Vesiculin in insulin sensitive and resistant mice. Peptides. PMID 31018156 DOI: 10.1016/J.Peptides.2019.04.011  1
2019 Ng J, Kaur H, Collier T, Chang K, Brooks AES, Allison JR, Brimble MA, Hickey A, Birch NP. Site-specific glycations of Aβ1-42 affect fibril formation and are neurotoxic. The Journal of Biological Chemistry. PMID 30996005 DOI: 10.1074/Jbc.Ra118.006846  1
2019 Forgiarini A, Wang Z, D'Amore C, Jay-Smith M, Li FF, Hopkins B, Brimble MA, Pagetta A, Bersani S, De Martin S, Napoli B, Bova S, Rennison D, Orso G. Live applications of norbormide-based fluorescent probes in Drosophila melanogaster. Plos One. 14: e0211169. PMID 30958824 DOI: 10.1371/Journal.Pone.0211169  1
2019 Cameron AJ, Squire CJ, Gérenton A, Stubbing LA, Harris PWR, Brimble MA. Investigations of the key macrolactamisation step in the synthesis of cyclic tetrapeptide pseudoxylallemycin A. Organic & Biomolecular Chemistry. PMID 30941386 DOI: 10.1039/C9Ob00227H  1
2019 Svendsen JSM, Grant TM, Rennison D, Brimble MA, Svenson J. Very Short and Stable Lactoferricin-Derived Antimicrobial Peptides: Design Principles and Potential Uses. Accounts of Chemical Research. PMID 30829472 DOI: 10.1021/Acs.Accounts.8B00624  1
2019 Lee DJ, Cameron AJ, Wright TH, Harris PWR, Brimble MA. A synthetic approach to 'click' neoglycoprotein analogues of EPO employing one-pot native chemical ligation and CuAAC chemistry. Chemical Science. 10: 815-828. PMID 30774876 DOI: 10.1039/C8Sc03409E  1
2019 Freeman JL, Brimble MA, Furkert DP. Convenient access to 5-membered cyclic iminium ions: evidence for a stepwise [4 + 2] cycloaddition mechanism. Organic & Biomolecular Chemistry. PMID 30768089 DOI: 10.1039/C9Ob00262F  1
2019 Davison EK, Brimble MA. Natural product derived privileged scaffolds in drug discovery. Current Opinion in Chemical Biology. 52: 1-8. PMID 30682725 DOI: 10.1016/J.Cbpa.2018.12.007  1
2019 Compton BJ, Farrand KJ, Tang CW, Osmond TL, Speir M, Authier-Hall A, Wang J, Ferguson PM, Chan STS, Anderson RJ, Cooney TR, Hayman CM, Williams GM, Brimble MA, Brooks CR, et al. Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist. Organic & Biomolecular Chemistry. PMID 30656346 DOI: 10.1039/C8Ob02982B  1
2019 Khalil ZG, Hill TA, De Leon Rodriguez LM, Lohman RJ, Hoang HN, Reiling N, Hillemann D, Brimble MA, Fairlie D, Blumenthal A, Capon RJ. Structure-activity relationships of wollamide cyclic hexapeptides with activity against drug-resistant and intracellular . Antimicrobial Agents and Chemotherapy. PMID 30602509 DOI: 10.1128/Aac.01773-18  1
2019 Li FF, Brimble MA. Using chemical synthesis to optimise antimicrobial peptides in the fight against antimicrobial resistance Pure and Applied Chemistry. 91: 181-198. DOI: 10.1515/Pac-2018-0704  1
2019 Freeman JL, Brimble MA, Furkert DP. A chiral auxiliary-based synthesis of the C5–C17 trans-decalin framework of anthracimycin Organic Chemistry Frontiers. 6: 2954-2963. DOI: 10.1039/C9Qo00769E  0.01
2019 Zhang S, Kavianinia I, Brimble MA. Naturally occurring antitubercular cyclic peptides Tetrahedron Letters. 60: 151339. DOI: 10.1016/J.Tetlet.2019.151339  1
2019 Yule LR, Garelja ML, Hendrikse ER, Gingell JJ, Poyner DR, Harris PWH, Brimble MA, Hay DL. A potent fluorescent calcitonin gene‐related peptide analogue enables visualization of receptor internalization Biopolymers. 111. DOI: 10.1002/Pep2.24126  1
2019 Xu B, Hermant Y, Yang S, Harris PWR, Brimble MA. Cover Feature: A Versatile Boc Solid Phase Synthesis of Daptomycin and Analogues Using Site Specific, On‐Resin Ozonolysis to Install the Kynurenine Residue (Chem. Eur. J. 62/2019) Chemistry: a European Journal. 25: 14024-14024. DOI: 10.1002/Chem.201904369  1
2018 Hauptstein N, De Leon-Rodriguez LM, Mitra AK, Hemar Y, Kavianinia I, Li N, Castelletto V, Hamley IW, Brimble MA. Supramolecular Threading of Peptide Hydrogel Fibrils. Acs Biomaterials Science & Engineering. 4: 2733-2738. PMID 33434999 DOI: 10.1021/Acsbiomaterials.8B00283  1
2018 Bower RL, Yule L, Rees TA, Deganutti G, Hendrikse ER, Harris PWR, Kowalczyk R, Ridgway Z, Wong AG, Swierkula K, Raleigh DP, Pioszak AA, Brimble MA, Reynolds CA, Walker CS, et al. Molecular Signature for Receptor Engagement in the Metabolic Peptide Hormone Amylin. Acs Pharmacology & Translational Science. 1: 32-49. PMID 32219203 DOI: 10.1021/acsptsci.8b00002  1
2018 Kasim JK, Kavianinia I, Ng J, Harris PWR, Birch NP, Brimble MA. Efficient synthesis and characterisation of the amyloid beta peptide, Aβ, using a double linker system. Organic & Biomolecular Chemistry. PMID 30500032 DOI: 10.1039/C8Ob02929F  1
2018 Janssens JV, Ma B, Brimble MA, Van Eyk JE, Delbridge LMD, Mellor KM. Cardiac troponins may be irreversibly modified by glycation: novel potential mechanisms of cardiac performance modulation. Scientific Reports. 8: 16084. PMID 30382112 DOI: 10.1038/S41598-018-33886-X  1
2018 D'Amore C, Orso G, Forgiarini A, Ceolotto G, Rennison D, Ribaudo G, Jay-Smith M, Hopkins B, Brimble MA, Bova S. Synthesis and Biological Characterization of a New Norbormide Derived Bodipy FL-Conjugated Fluorescent Probe for Cell Imaging. Frontiers in Pharmacology. 9: 1055. PMID 30319407 DOI: 10.3389/Fphar.2018.01055  1
2018 Xu B, Aitken EJ, Baker BP, Turner CA, Harvey JE, Stott MB, Power JF, Harris PWR, Keyzers RA, Brimble MA. Genome mining, isolation, chemical synthesis and biological evaluation of a novel lanthipeptide, tikitericin, from the extremophilic microorganism strain T81. Chemical Science. 9: 7311-7317. PMID 30294420 DOI: 10.1039/C8Sc02170H  1
2018 Ding XB, Brimble MA, Furkert DP. Reactivity of 2-Nitropyrrole Systems: Development of Improved Synthetic Approaches to Nitropyrrole Natural Products. The Journal of Organic Chemistry. PMID 30270625 DOI: 10.1021/Acs.Joc.8B01692  1
2018 Pilkington L, Yang X, Liu MW, Hemar Y, Brimble M, Reynisson J. A chemometric analysis of compounds from native New Zealand medicinal flora. Chemistry, An Asian Journal. PMID 30125474 DOI: 10.1002/Asia.201800803  1
2018 Grant P, Brimble M, Furkert DP. Synthesis of the Bicyclic Lactone Core of Leonuketal Enabled by a Telescoped Diels-Alder Reaction Sequence. Chemistry, An Asian Journal. PMID 30058292 DOI: 10.1002/Asia.201800903  1
2018 Wood JM, Furkert DP, Brimble MA. 2-Formylpyrrole natural products: origin, structural diversity, bioactivity and synthesis. Natural Product Reports. PMID 30039828 DOI: 10.1039/C8Np00051D  1
2018 Simms J, Uddin R, Sakmar TP, Gingell JJ, Garelja ML, Hay DL, Brimble MA, Harris PWR, Reynolds CA, Poyner DR. Photoaffinity cross-linking and unnatural amino acid mutagenesis reveal insights into calcitonin gene-related peptide binding to the calcitonin receptor-like receptor/receptor activity-modifying protein 1 (CLR/RAMP1) complex. Biochemistry. PMID 30004692 DOI: 10.1021/Acs.Biochem.8B00502  1
2018 Zhang S, De Leon Rodriguez LM, Huang R, Leung IKH, Harris PWR, Brimble MA. Total synthesis of the proposed structure of talarolide A. Organic & Biomolecular Chemistry. PMID 29989642 DOI: 10.1039/C8Ob01230J  1
2018 Brimble MA, De Leon Rodriguez L, Williams E. Chemical Synthesis of Bioactive Naturally Derived Cyclic Peptides Containing Ene-Like Rigidifying Motifs. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29987917 DOI: 10.1002/Chem.201802533  1
2018 Brimble MA, Williams ET, Harris PW, Loomes K, Hay DL, Jamaluddin MA. Solid-Phase Thiol-ene Lipidation of Peptides for the Synthesis of a Potent CGRP Receptor Antagonist. Angewandte Chemie (International Ed. in English). PMID 29978532 DOI: 10.1002/Anie.201805208  1
2018 Fan D, Alamri Y, Liu K, MacAskill M, Harris P, Brimble M, Dalrymple-Alford J, Prickett T, Menzies O, Laurenson A, Anderson T, Guan J. Supplementation of Blackcurrant Anthocyanins Increased Cyclic Glycine-Proline in the Cerebrospinal Fluid of Parkinson Patients: Potential Treatment to Improve Insulin-Like Growth Factor-1 Function. Nutrients. 10. PMID 29865234 DOI: 10.3390/Nu10060714  1
2018 Heikal A, Nakatani Y, Jiao W, Wilson C, Rennison D, Weimar MR, Parker EJ, Brimble MA, Cook GM. 'Tethering' fragment-based drug discovery to identify inhibitors of the essential respiratory membrane protein type II NADH dehydrogenase. Bioorganic & Medicinal Chemistry Letters. PMID 29859905 DOI: 10.1016/J.Bmcl.2018.05.048  1
2018 Bisset SW, Yang SH, Amso Z, Harris PWR, Patchett ML, Brimble MA, Norris GE. Using Chemical Synthesis to Probe Structure-Activity Relationships of the Glycoactive Bacteriocin Glycocin F. Acs Chemical Biology. PMID 29701461 DOI: 10.1021/Acschembio.8B00055  1
2018 Amso Z, Bisset SW, Yang SH, Harris PWR, Wright TH, Navo CD, Patchett ML, Norris GE, Brimble MA. Total chemical synthesis of glycocin F and analogues: -glycosylation confers improved antimicrobial activity. Chemical Science. 9: 1686-1691. PMID 29675216 DOI: 10.1039/C7Sc04383J  1
2018 Shirley HJ, Jamieson ML, Brimble MA, Bray CD. A new family of sesterterpenoids isolated around the Pacific Rim. Natural Product Reports. PMID 29547216 DOI: 10.1039/C7Np00049A  1
2018 Pantin M, Brimble MA, Furkert DP. Total Synthesis of (-)-Peniphenone A. The Journal of Organic Chemistry. PMID 29480005 DOI: 10.1021/Acs.Joc.7B03231  1
2018 Alexander SR, Williams GM, Brimble MA, Fairbanks AJ. A double-click approach to the protecting group free synthesis of glycoconjugates. Organic & Biomolecular Chemistry. PMID 29406545 DOI: 10.1039/C8Ob00072G  1
2018 Garelja ML, Walker CA, Siow A, Yang SH, Harris PWR, Brimble MA, Watkins HA, Gingell JJ, Hay DL. Receptor activity-modifying proteins have limited effects on the class B G protein-coupled receptor calcitonin receptor-like receptor stalk. Biochemistry. PMID 29388762 DOI: 10.1021/Acs.Biochem.7B01180  1
2018 Brimble MA, Zhang S, De Leon Rodriguez L, Leung I, Cook G, Harris P. Total Synthesis and Conformational Study of The Anti-tubercular Cyclic Peptide Callyaerin A Bearing a Rare Rigidifying (Z)-2,3- Diaminoacrylamide Moiety. Angewandte Chemie (International Ed. in English). PMID 29345033 DOI: 10.1002/Anie.201712792  1
2018 Siow A, Opiyo G, Kavianinia I, Li FF, Furkert DP, Harris PWR, Brimble MA. Total Synthesis of the Highly N-Methylated Acetylene-Containing Anticancer Peptide Jahanyne. Organic Letters. PMID 29337569 DOI: 10.1021/Acs.Orglett.7B03925  1
2018 Amso Z, Bisset SW, Yang S, Harris PWR, Wright TH, Navo CD, Patchett ML, Norris GE, Brimble MA. Total chemical synthesis of glycocin F and analogues: S-glycosylation confers improved antimicrobial activity Chemical Science. DOI: 10.1039/C7SC04383J  1
2018 Rodriguez LMDL, Williams ET, Brimble MA. Frontispiece: Chemical Synthesis of Bioactive Naturally Derived Cyclic Peptides Containing Ene‐Like Rigidifying Motifs Chemistry: a European Journal. 24. DOI: 10.1002/Chem.201886862  1
2018 Zhang S, Rodriguez LMDL, Leung IKH, Cook GM, Harris PWR, Brimble MA. Inside Back Cover: Total Synthesis and Conformational Study of Callyaerin A: Anti‐Tubercular Cyclic Peptide Bearing a Rare Rigidifying (Z)‐2,3‐ Diaminoacrylamide Moiety (Angew. Chem. Int. Ed. 14/2018) Angewandte Chemie. 57: 3835-3835. DOI: 10.1002/Anie.201801945  1
2018 Zhang S, Rodriguez LMDL, Leung IKH, Cook GM, Harris PWR, Brimble MA. Innenrücktitelbild: Total Synthesis and Conformational Study of Callyaerin A: Anti‐Tubercular Cyclic Peptide Bearing a Rare Rigidifying (Z)‐2,3‐ Diaminoacrylamide Moiety (Angew. Chem. 14/2018) Angewandte Chemie. 130: 3897-3897. DOI: 10.1002/Ange.201801945  1
2017 Mountjoy KG, Caron A, Hubbard K, Shome A, Grey AC, Sun B, Bould S, Middleditch M, Pontré B, McGregor A, Harris PWR, Kowalczyk R, Brimble MA, Botha R, Tan KML, et al. Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance. Molecular Metabolism. PMID 29226825 DOI: 10.1016/J.Molmet.2017.11.008  1
2017 Evans GL, Furkert DP, Abermil N, Kundu P, de Lange KM, Parker EJ, Brimble MA, Baker EN, Lott JS. Datasets, processing and refinement details for Mtb-AnPRT: inhibitor structures with various space groups. Data in Brief. 15: 1019-1029. PMID 29167811 DOI: 10.1016/J.Dib.2017.10.051  1
2017 Cho CAH, Liang C, Perera J, Liu J, Varnava KG, Sarojini V, Cooney RP, McGillivray DJ, Brimble MA, Swift S, Jin J. Molecular Weight and Charge Density Effects of Guanidinylated Biodegradable Polycarbonates on Antimicrobial Activity and Selectivity. Biomacromolecules. PMID 29125279 DOI: 10.1021/Acs.Biomac.7B01245  1
2017 Iborra RT, Machado-Lima A, Okuda LS, Pinto PR, Nakandakare ER, Machado UF, Correa-Giannella ML, Pickford R, Woods T, Brimble MA, Rye KA, Lu R, Yokoyama S, Passarelli M. AGE-albumin enhances ABCA1 degradation by ubiquitin-proteasome and lysosomal pathways in macrophages. Journal of Diabetes and Its Complications. PMID 29097054 DOI: 10.1016/J.Jdiacomp.2017.09.012  1
2017 Gasser O, Sharples KJ, Barrow C, Williams GM, Bauer E, Wood CE, Mester B, Dzhelali M, Caygill G, Jones J, Hayman CM, Hinder VA, Macapagal J, McCusker M, Weinkove R, ... ... Brimble MA, et al. A phase I vaccination study with dendritic cells loaded with NY-ESO-1 and α-galactosylceramide: induction of polyfunctional T cells in high-risk melanoma patients. Cancer Immunology, Immunotherapy : Cii. PMID 29094183 DOI: 10.1007/S00262-017-2085-9  1
2017 Kowalczyk R, Harris PWR, Williams GM, Yang SH, Brimble MA. Peptide Lipidation - A Synthetic Strategy to Afford Peptide Based Therapeutics. Advances in Experimental Medicine and Biology. 1030: 185-227. PMID 29081055 DOI: 10.1007/978-3-319-66095-0_9  1
2017 Anderson RJ, Li J, Kedzierski L, Compton BJ, Hayman CM, Osmond TL, Tang CW, Farrand KJ, Koay HF, Almeida CFDSSE, Holz LR, Williams GM, Brimble MA, Wang Z, Koutsakos M, et al. Augmenting influenza-specific T cell memory generation with a NKT cell-dependent glycolipid-peptide vaccine. Acs Chemical Biology. PMID 29043774 DOI: 10.1021/Acschembio.7B00845  1
2017 da Silva KS, Pinto PR, Fabre NT, Gomes DJ, Thieme K, Okuda LS, Iborra RT, Freitas VG, Shimizu MHM, Teodoro WR, Marie SKN, Woods T, Brimble MA, Pickford R, Rye KA, et al. N-acetylcysteine Counteracts Adipose Tissue Macrophage Infiltration and Insulin Resistance Elicited by Advanced Glycated Albumin in Healthy Rats. Frontiers in Physiology. 8: 723. PMID 29018354 DOI: 10.3389/Fphys.2017.00723  1
2017 Schumacher CE, Harris PWR, Ding XB, Krause B, Wright TH, Cook GM, Furkert DP, Brimble MA. Synthesis and biological evaluation of novel teixobactin analogues. Organic & Biomolecular Chemistry. PMID 28993827 DOI: 10.1039/C7Ob02169K  1
2017 Kueh JTB, Stanley NJ, Hewitt RJ, Woods LM, Larsen L, Harrison JC, Rennison D, Brimble MA, Sammut IA, Larsen DS. Norborn-2-en-7-ones as physiologically-triggered carbon monoxide-releasing prodrugs. Chemical Science. 8: 5454-5459. PMID 28970925 DOI: 10.1039/C7Sc01647F  1
2017 Pantin M, Hubert JG, Söhnel T, Brimble MA, Furkert DP. Stereochemical Characterisation of Polyketide Stereotriads Synthesized via Hydrogen Mediated Asymmetric Syn-Crotylation. The Journal of Organic Chemistry. PMID 28960976 DOI: 10.1021/Acs.Joc.7B01820  1
2017 Ding XB, Furkert DP, Brimble MA. General Synthesis of the Nitropyrrolin Family of Natural Products via Regioselective CO2-Mediated Alkyne Hydration. Organic Letters. PMID 28898092 DOI: 10.1021/Acs.Orglett.7B02687  1
2017 De Leon-Rodriguez LM, Hemar Y, Mitra AK, Brimble MA. Understanding the metal mediated assembly and hydrogel formation of a β-hairpin peptide. Biomaterials Science. PMID 28853745 DOI: 10.1039/C7Bm00512A  1
2017 Evans GL, Furkert DP, Abermil N, Kundu P, de Lange KM, Parker EJ, Brimble MA, Baker EN, Shaun Lott J. Anthranilate phosphoribosyltransferase: Binding determinants for 5'-phospho-alpha-d-ribosyl-1'-pyrophosphate (PRPP) and the implications for inhibitor design. Biochimica Et Biophysica Acta. PMID 28844746 DOI: 10.1016/J.Bbapap.2017.08.018  1
2017 Kavianinia I, Yang SH, Kaur H, Harris PWR, Dobson RCJ, Fairbanks AJ, Brimble MA. Synthesis and incorporation of an advanced lipid peroxidation end-product building block into collagen mimetic peptides. Chemical Communications (Cambridge, England). PMID 28702630 DOI: 10.1039/C7Cc05025A  1
2017 Lutteroth KR, Harris PWR, Wright TH, Kaur H, Sparrow K, Yang SH, Cooper GJS, Brimble MA. Incorporation of 'click' chemistry glycomimetics dramatically alters triple-helix stability in an adiponectin model peptide. Organic & Biomolecular Chemistry. PMID 28639641 DOI: 10.1039/C7Ob01388D  1
2017 Badrinarayanan S, Squire CJ, Sperry J, Brimble MA. Bioinspired Total Synthesis and Stereochemical Revision of the Fungal Metabolite Pestalospirane B. Organic Letters. PMID 28621951 DOI: 10.1021/Acs.Orglett.7B01371  1
2017 Wood JM, Furkert DP, Brimble MA. Total Synthesis and Stereochemical Revision of the 2-Formylpyrrole Alkaloid Hemerocallisamine I. Journal of Natural Products. PMID 28590122 DOI: 10.1021/Acs.Jnatprod.7B00314  1
2017 Choi H, Shirley HJ, Hume PA, Brimble MA, Furkert DP. Unexpected Direct Synthesis of N-Vinyl Amides through Vinyl Azide-Enolate [3+2] Cycloaddition. Angewandte Chemie (International Ed. in English). PMID 28544052 DOI: 10.1002/Anie.201702727  1
2017 Hung KY, Harris PWR, Desai A, Marshall JF, Brimble MA. Structure-activity relationship study of the tumour-targeting peptide A20FMDV2 via modification of Lys16, Leu13, and N- and/or C-terminal functionality. European Journal of Medicinal Chemistry. 136: 154-164. PMID 28494253 DOI: 10.1016/J.Ejmech.2017.05.008  0.28
2017 Stubbing LA, Kavianinia I, Brimble MA. Synthesis of AHMOD-containing aminolipopeptides, unique bioactive peptaibiotics. Organic & Biomolecular Chemistry. PMID 28398442 DOI: 10.1039/C7Ob00541E  1
2017 Quach R, Furkert DP, Brimble MA. Gold catalysis: synthesis of spiro, bridged, and fused ketal natural products. Organic & Biomolecular Chemistry. PMID 28287235 DOI: 10.1039/C7Ob00496F  1
2017 Alexander SR, Lim D, Amso Z, Brimble MA, Fairbanks AJ. Protecting group free synthesis of glycosyl thiols from reducing sugars in water; application to the production of N-glycan glycoconjugates. Organic & Biomolecular Chemistry. PMID 28211926 DOI: 10.1039/C7Ob00112F  0.01
2017 Medini K, West B, Williams DE, Brimble MA, Gerrard JA. MALDI-imaging enables direct observation of kinetic and thermodynamic products of mixed peptide fiber assembly. Chemical Communications (Cambridge, England). PMID 28102381 DOI: 10.1039/C6Cc10146A  1
2017 Harris PWR, Cook GM, Leung IKH, Brimble MA. An Efficient Chemical Synthesis of Lassomycin Enabled by an On-Resin Lactamisation–Off-Resin Methanolysis Strategy and Preparation of Chemical Variants Australian Journal of Chemistry. 70: 172-183. DOI: 10.1071/Ch16499  1
2017 Knochel P, Hammann JM, Choi H, Shirley HJ, Hume PA, Brimble MA, Furkert DP. Vinyl Azide Enolate [3+2] Cycloaddition Synfacts. 13: 864-7424. DOI: 10.1055/S-0036-1590632  1
2017 Jamieson M, Brant N, Brimble M, Furkert D. Remarkable Influence of Cobalt Catalysis on Epoxide Ring-Opening with Sulfoxonium Ylides Synthesis. 49: 3952-3956. DOI: 10.1055/S-0036-1588814  0.01
2017 McGrath AJ, Dolan C, Cheong S, Herman DAJ, Naysmith B, Zong F, Galvosas P, Farrand KJ, Hermans IF, Brimble M, Williams DE, Jin J, Tilley RD. Stability of polyelectrolyte-coated iron nanoparticles for T2-weighted magnetic resonance imaging Journal of Magnetism and Magnetic Materials. 439: 251-258. DOI: 10.1016/J.Jmmm.2017.04.026  1
2017 Siow A, Hung K, Harris PWR, Brimble MA. Solid‐Phase Synthesis of the Peptaibol Alamethicin U‐22324 by Using a Double‐Linker Strategy European Journal of Organic Chemistry. 2017: 350-354. DOI: 10.1002/Ejoc.201601102  1
2017 Zhang S, Rodriguez LMDL, Harris PWR, Brimble MA. Synthesis of Enediamino Amino Acid Analogues and Peptides Asian Journal of Organic Chemistry. 6: 1113-1113. DOI: 10.1002/Ajoc.201700243  1
2016 Medini K, Harris PWR, Menorca A, Hards K, Cook GM, Brimble MA. Synthesis and activity of a diselenide bond mimetic of the antimicrobial protein caenopore-5. Chemical Science. 7: 2005-2010. PMID 29899924 DOI: 10.1039/C5Sc04187B  1
2016 Atkinson DJ, Naysmith BJ, Furkert DP, Brimble MA. Enduracididine, a rare amino acid component of peptide antibiotics: Natural products and synthesis. Beilstein Journal of Organic Chemistry. 12: 2325-2342. PMID 28144300 DOI: 10.3762/Bjoc.12.226  1
2016 Kim Y, Griffin JM, Harris PW, Chan SH, Nicholson LF, Brimble MA, O'Carroll SJ, Green CR. Characterizing the mode of action of extracellular Connexin43 channel blocking mimetic peptides in an in vitro ischemia injury model. Biochimica Et Biophysica Acta. PMID 27816754 DOI: 10.1016/J.Bbagen.2016.11.001  1
2016 Kamato D, Mitra P, Davis F, Osman N, Chaplin R, Cabot PJ, Afroz R, Thomas W, Zheng W, Kaur H, Brimble M, Little PJ. Gaq proteins: molecular pharmacology and therapeutic potential. Cellular and Molecular Life Sciences : Cmls. PMID 27815595 DOI: 10.1007/S00018-016-2405-9  1
2016 Naysmith BJ, Hume PA, Sperry J, Brimble MA. Pyranonaphthoquinones - isolation, biology and synthesis: an update. Natural Product Reports. PMID 27759131 DOI: 10.1039/C6Np00080K  1
2016 De Leon-Rodriguez LM, Hemar Y, Mo G, Mitra AK, Cornish J, Brimble MA. Multifunctional thermoresponsive designer peptide hydrogels. Acta Biomaterialia. PMID 27744067 DOI: 10.1016/J.Actbio.2016.10.014  1
2016 Ding XB, Furkert DP, Brimble MA. 2-Nitropyrrole cross-coupling enables a second generation synthesis of the heronapyrrole antibiotic natural product family. Chemical Communications (Cambridge, England). PMID 27722263 DOI: 10.1039/C6Cc07532K  1
2016 D'Amore C, Orso G, Fusi F, Pagano MA, Miotto G, Forgiarini A, De Martin S, Castellani G, Ribaudo G, Rennison D, Brimble MA, Hopkins B, Ferrarese A, Bova S. An NBD Derivative of the Selective Rat Toxicant Norbormide as a New Probe for Living Cell Imaging. Frontiers in Pharmacology. 7: 315. PMID 27721792 DOI: 10.3389/Fphar.2016.00315  1
2016 Kaur H, Kamalov M, Brimble MA. Chemical Synthesis of Peptides Containing Site-Specific Advanced Glycation Endproducts. Accounts of Chemical Research. PMID 27672697 DOI: 10.1021/Acs.Accounts.6B00366  1
2016 Quach R, Furkert DP, Brimble MA. Total Synthesis of the Resorcyclic Acid Lactone Spiroketal Citreoviranol. The Journal of Organic Chemistry. PMID 27505436 DOI: 10.1021/Acs.Joc.6B01503  1
2016 Amso Z, Kowalczyk R, Watson M, Park YE, Callon KE, Musson DS, Cornish J, Brimble MA. Structure activity relationship study on the peptide hormone preptin, a novel bone-anabolic agent for the treatment of osteoporosis. Organic & Biomolecular Chemistry. PMID 27488745 DOI: 10.1039/C6Ob01455K  0.08
2016 Kavianinia I, Kunalingam L, Harris PW, Cook GM, Brimble MA. Total Synthesis and Stereochemical Revision of the Anti-Tuberculosis Peptaibol Trichoderin A. Organic Letters. PMID 27467118 DOI: 10.1021/Acs.Orglett.6B01886  1
2016 Wood JM, Furkert DP, Brimble MA. Synthesis of the 2-formylpyrrole spiroketal pollenopyrroside A and structural elucidation of xylapyrroside A, shensongine A and capparisine B. Organic & Biomolecular Chemistry. PMID 27452965 DOI: 10.1039/C6Ob01361A  1
2016 Ngen ST, Kaur H, Hume PA, Furkert DP, Brimble MA. Synthesis of Psychrophilin E. The Journal of Organic Chemistry. PMID 27442351 DOI: 10.1021/Acs.Joc.6B01369  1
2016 Wang Z, Krogsgaard-Larsen N, Daniels B, Furkert DP, Brimble MA. Cyclic Enecarbamates as Precursors of alpha,beta-Unsaturated Iminium Ions: Reactivity and Synthesis of 6,6-Spirocyclic Ring Systems. The Journal of Organic Chemistry. PMID 27441647 DOI: 10.1021/Acs.Joc.6B01343  1
2016 Gomes DJ, Velosa AP, Okuda LS, Fusco FB, da Silva KS, Pinto PR, Nakandakare ER, Correa-Giannella ML, Woods T, Brimble MA, Pickford R, Rye KA, Teodoro WR, Catanozi S, Passarelli M. Glycated albumin induces lipid infiltration in mice aorta independently of DM and RAS local modulation by inducing lipid peroxidation and inflammation. Journal of Diabetes and Its Complications. PMID 27440461 DOI: 10.1016/J.Jdiacomp.2016.07.001  1
2016 Medini K, Mansel BW, Williams MA, Brimble MA, Williams DE, Gerrard JA. Controlling gelation with sequence: towards programmable peptide hydrogels. Acta Biomaterialia. PMID 27424085 DOI: 10.1016/J.Actbio.2016.07.021  1
2016 Yim V, Noisier AF, Hung KY, Bartsch JW, Schlomann U, Brimble MA. Synthesis and biological evaluation of analogues of the potent ADAM8 inhibitor cyclo(RLsKDK) for the treatment of inflammatory diseases and cancer metastasis. Bioorganic & Medicinal Chemistry. PMID 27407033 DOI: 10.1016/J.Bmc.2016.06.042  1
2016 Singh-Mallah G, Singh K, McMahon CD, Harris P, Brimble MA, Thorstensen E, Guan J. Maternally administered cyclic-glycine-proline increases insulin-like growth factor-1 bioavailability and novelty recognition in developing offspring. Endocrinology. en20161189. PMID 27355491 DOI: 10.1210/En.2016-1189  1
2016 Zhang S, Amso Z, De Leon Rodriguez LM, Kaur H, Brimble MA. Synthesis of Natural Cyclopentapeptides Isolated from Dianthus chinensis. Journal of Natural Products. PMID 27326468 DOI: 10.1021/Acs.Jnatprod.6B00152  1
2016 De Leon Rodriguez LM, Hemar Y, Cornish J, Brimble MA. Structure-mechanical property correlations of hydrogel forming β-sheet peptides. Chemical Society Reviews. PMID 27301699 DOI: 10.1039/C5Cs00941C  1
2016 Amso Z, Cornish J, Brimble MA. Short Anabolic Peptides for Bone Growth. Medicinal Research Reviews. 36: 579-640. PMID 27297498 DOI: 10.1002/Med.21388  1
2016 Eurtivong C, Reynisdóttir I, Kuczma S, Furkert DP, Brimble MA, Reynisson J. Identification of anticancer agents based on the thieno[2,3-b]pyridine and 1H-pyrazole molecular scaffolds. Bioorganic & Medicinal Chemistry. PMID 27288184 DOI: 10.1016/J.Bmc.2016.05.061  1
2016 Amso Z, Kowalczyk R, Park YE, Watson M, Lin JM, Musson DS, Cornish J, Brimble MA. Synthesis and in vitro bone cell activity of analogues of the cyclohexapeptide dianthin G. Organic & Biomolecular Chemistry. PMID 27264279 DOI: 10.1039/C6Ob00983B  1
2016 Daniels BJ, Prijic G, Meidinger S, Loomes KM, Stephens JM, Schlothauer RC, Furkert DP, Brimble MA. Isolation, Structural Elucidation and Synthesis of Lepteridine from Mānuka Honey. Journal of Agricultural and Food Chemistry. PMID 27210444 DOI: 10.1021/Acs.Jafc.6B01596  1
2016 Yeung H, Squire CJ, Yosaatmadja Y, Panjikar S, López G, Molina A, Baker EN, Harris PW, Brimble MA. Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily. Angewandte Chemie (International Ed. in English). PMID 27145301 DOI: 10.1002/Anie.201602719  1
2016 Choi H, Conole D, Atkinson DJ, Laita O, Jay-Smith M, Pagano MA, Ribaudo G, Cavalli M, Bova S, Hopkins B, Brimble MA, Rennison D. Fatty Acid Derived Pro-toxicants of the Rat Selective Toxicant Norbormide. Chemistry & Biodiversity. PMID 27144301 DOI: 10.1002/Cbdv.201500241  1
2016 Yule LR, Bower RL, Kaur H, Kowalczyk R, Hay DL, Brimble MA. Synthesis and amylin receptor activity of glycomimetics of pramlintide using click chemistry. Organic & Biomolecular Chemistry. PMID 27139251 DOI: 10.1039/C6Ob00850J  1
2016 Watkins HA, Chakravarthy M, Abhayawardana RS, Gingell JJ, Garelja M, Pardamwar M, McElhinney JM, Lathbridge A, Constantine A, Harris PW, Yuen TY, Brimble MA, Barwell J, Poyner DR, Woolley MJ, et al. Receptor Activity-Modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties. The Journal of Biological Chemistry. PMID 27013657 DOI: 10.1074/Jbc.M115.688218  1
2016 Son SJ, Harris PW, Squire CJ, Baker EN, Brimble MA. Synthesis and structural insight into ESX-1 substrate protein C (EspC), an immunodominant Mycobacterium tuberculosis-secreted antigen. Biopolymers. PMID 26999334 DOI: 10.1002/Bip.22838  1
2016 De Leon-Rodriguez LM, Kamalov M, Hemar Y, Mitra AK, Castelletto V, Hermida-Merino D, Hamley IW, Brimble MA. A peptide hydrogel derived from a fragment of human cardiac troponin C. Chemical Communications (Cambridge, England). PMID 26892840 DOI: 10.1039/C6Cc00209A  1
2016 Ding XB, Brimble MA, Furkert DP. Nitropyrrole natural products: isolation, biosynthesis and total synthesis. Organic & Biomolecular Chemistry. PMID 26879381 DOI: 10.1039/C5Ob02599K  1
2016 Ting YT, Harris PW, Batot G, Brimble MA, Baker EN, Young PG. Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization. Iucrj. 3: 10-9. PMID 26870377 DOI: 10.1107/S2052252515019971  1
2016 Cottam Jones JM, Harris PW, Scanlon DB, Forbes BE, Brimble MA, Abell AD. Fluorescent IGF-II analogues for FRET-based investigations into the binding of IGF-II to the IGF-1R. Organic & Biomolecular Chemistry. 14: 2698-705. PMID 26839188 DOI: 10.1039/C5Ob02110C  1
2016 Jamieson ML, Hume PA, Furkert DP, Brimble MA. Divergent Reactivity via Cobalt Catalysis: An Epoxide Olefination. Organic Letters. 18: 468-71. PMID 26829490 DOI: 10.1021/Acs.Orglett.5B03514  1
2016 Kamalov M, Kaur H, Brimble MA. Intermolecular Peptide Cross-Linking by Using Diaminodicarboxylic Acids. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26749083 DOI: 10.1002/Chem.201503458  1
2016 Sidgwick GP, Walling P, Shabbir A, Weston R, Schiro A, Serracino-Inglott F, Jones AM, Kamalov M, Brimble MA, Wilkinson FL, Alexander MY. 196 Strategies for Inhibiting Advanced Glycation Endproduct (Age) Induced Vascular Calcification in a Smooth Muscle Cell Culture Model Heart. 102. DOI: 10.1136/Heartjnl-2016-309890.196  1
2016 Rennison D, Gueret SM, Laita O, Bland RJ, Sutherland IA, Boddy IK, Brimble MA. Substituted Carbazoles – A New Class of Anthelmintic Agent Australian Journal of Chemistry. 69: 1268-1276. DOI: 10.1071/Ch16169  1
2016 Dolan C, Drouet F, Ware DC, Brothers PJ, Jin J, Brimble MA, Williams DE. A new high-capacity metal ion-complexing gel containing cyclen ligands Rsc Advances. 6: 23645-23652. DOI: 10.1039/C6Ra00604C  1
2016 Medini K, Harris PWR, Menorca A, Hards K, Cook GM, Brimble MA. Synthesis and activity of a diselenide bond mimetic of the antimicrobial protein caenopore-5 Chemical Science. 7: 2005-2010. DOI: 10.1039/c5sc04187b  1
2016 Jay-Smith M, Murphy EC, Shapiro L, Eason CT, Brimble MA, Rennison D. Stereoselective synthesis of the rat selective toxicant norbormide Tetrahedron. 72: 5331-5342. DOI: 10.1016/J.Tet.2016.07.014  1
2016 Dickson E, Pilkington LI, Brimble MA, Barker D. Enantioselective synthesis of BE ring analogues of methyllycaconitine Tetrahedron. 72: 400-414. DOI: 10.1016/J.Tet.2015.11.057  1
2016 Strover LT, Malmström J, Stubbing LA, Brimble MA, Travas-Sejdic J. Corrigendum to ‘Electrochemically-controlled grafting of hydrophilic brushes from conducting polymer substrates’ [Electrochimica Acta 188 (2016) 57–70] Electrochimica Acta. 189: 303. DOI: 10.1016/J.Electacta.2016.01.203  0.01
2016 Strover LT, Malmström J, Stubbing LA, Brimble MA, Travas-Sejdic J. Electrochemically-controlled grafting of hydrophilic brushes from conducting polymer substrates Electrochimica Acta. 188: 57-70. DOI: 10.1016/J.Electacta.2015.11.106  1
2016 Amso Z, Cornish J, Brimble MA. Short Anabolic Peptides for Bone Growth Medicinal Research Reviews. DOI: 10.1002/med.21388  1
2016 Zhang S, De Leon Rodriguez LM, Lacey E, Piggott AM, Leung IKH, Brimble MA. Cyclization of Linear Tetrapeptides Containing N -Methylated Amino Acids by using 1-Propanephosphonic Acid Anhydride European Journal of Organic Chemistry. 2017: 149-158. DOI: 10.1002/Ejoc.201601016  0.01
2016 Li FF, Atkinson DJ, Furkert DP, Brimble MA. A Convergent Synthesis of Gonytolide C Using an Intramolecular Oxa-Michael Addition European Journal of Organic Chemistry. 2016: 1145-1155. DOI: 10.1002/Ejoc.201501402  1
2016 Yang SH, Harris PWR, Williams GM, Brimble MA. Lipidation of Cysteine or Cysteine-Containing Peptides Using the Thiol-Ene Reaction (CLipPA) European Journal of Organic Chemistry. DOI: 10.1002/Ejoc.201501375  1
2016 Chorley DF, Furkert DP, Brimble MA. Synthesis of the Spiroketal Core of the Pinnatifinoside Family of Natural Products European Journal of Organic Chemistry. 2016: 314-319. DOI: 10.1002/Ejoc.201501225  1
2016 Rong J, Pellegrini T, Harutyunyan SR, Šponer JE, Šponer J, Nováková O, Brabec V, Šedo O, Zdráhal Z, Costanzo G, Pino S, Saladino R, Mauro ED, Kamalov M, Kaur H, ... Brimble MA, et al. Cover Picture: Synthesis of Chiral Tertiary Alcohols by CuI-Catalyzed Enantioselective Addition of Organomagnesium Reagents to Ketones / Emergence of the First Catalytic Oligonucleotides in a Formamide-Based Origin Scenario / Intermolecular Peptide Cross- Chemistry: a European Journal. 22: 3521-3521. DOI: 10.1002/Chem.201600250  1
2016 Yeung H, Squire CJ, Yosaatmadja Y, Panjikar S, López G, Molina A, Baker EN, Harris PWR, Brimble MA. Cover Picture: Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily (Angew. Chem. Int. Ed. 28/2016) Angewandte Chemie International Edition. 55: 7865-7865. DOI: 10.1002/Anie.201604250  0.04
2016 Yeung H, Squire CJ, Yosaatmadja Y, Panjikar S, López G, Molina A, Baker EN, Harris PWR, Brimble MA. Titelbild: Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily (Angew. Chem. 28/2016) Angewandte Chemie. 128: 7995-7995. DOI: 10.1002/Ange.201604250  0.01
2015 Anderson RJ, Compton BJ, Tang CW, Authier-Hall A, Hayman CM, Swinerd GW, Kowalczyk R, Harris P, Brimble MA, Larsen DS, Gasser O, Weinkove R, Hermans IF, Painter GF. NKT cell-dependent glycolipid-peptide vaccines with potent anti-tumour activity. Chemical Science. 6: 5120-5127. PMID 28717498 DOI: 10.1039/C4Sc03599B  1
2015 McIntosh JD, Brimble MA, Brooks AES, Dunbar PR, Kowalczyk R, Tomabechi Y, Fairbanks AJ. Convergent chemo-enzymatic synthesis of mannosylated glycopeptides; targeting of putative vaccine candidates to antigen presenting cells. Chemical Science. 6: 4636-4642. PMID 28717478 DOI: 10.1039/C5Sc00952A  1
2015 Panwalkar V, Neudecker P, Schmitz M, Lecher J, Schulte M, Medini K, Stoldt M, Brimble MA, Willbold D, Dingley AJ. The Nedd4-1 WW domain recognizes the PY motif peptide through a coupled folding-binding equilibrium. Biochemistry. PMID 26685112 DOI: 10.1021/Acs.Biochem.5B01028  1
2015 Kamato D, Thach L, Bernard R, Chan V, Zheng W, Kaur H, Brimble M, Osman N, Little PJ. Structure, Function, Pharmacology, and Therapeutic Potential of the G Protein, Gα/q,11. Frontiers in Cardiovascular Medicine. 2: 14. PMID 26664886 DOI: 10.3389/Fcvm.2015.00014  1
2015 Poral VL, Furkert DP, Brimble MA. Total Synthesis and Structural Confirmation of the Antimalarial Naphthopyrone Lasionectrin. Organic Letters. 17: 6214-7. PMID 26650711 DOI: 10.1021/Acs.Orglett.5B03202  1
2015 De Leon Rodriguez LM, Kaur H, Brimble MA. Synthesis and bioactivity of antitubercular peptides and peptidomimetics: an update. Organic & Biomolecular Chemistry. PMID 26645944 DOI: 10.1039/C5Ob02298C  1
2015 Whiting L, Stewart KW, Hay DL, Harris PW, Choong YS, Phillips AR, Brimble MA, Cooper GJ. Glicentin-related pancreatic polypeptide inhibits glucose-stimulated insulin secretion from the isolated pancreas of adult male rats. Physiological Reports. 3. PMID 26634904 DOI: 10.14814/Phy2.12638  1
2015 Brimble MA, Reiss UM, Nathwani AC, Davidoff AM. New and improved AAVenues: current status of hemophilia B gene therapy. Expert Opinion On Biological Therapy. 1-14. PMID 26524468 DOI: 10.1517/14712598.2015.1106475  1
2015 Ko KY, Wagner S, Yang SH, Furkert DP, Brimble MA. Improved Synthesis of the Unnatural Amino Acids AHMOD and AMD, Components of the Anticancer Peptaibol Culicinin D. The Journal of Organic Chemistry. PMID 26252224 DOI: 10.1021/Acs.Joc.5B01265  1
2015 Hampe L, Radjainia M, Xu C, Harris PW, Bashiri G, Goldstone DC, Brimble MA, Wang Y, Mitra AK. Regulation and Quality Control of Adiponectin Assembly by Endoplasmic Reticulum Chaperone ERp44. The Journal of Biological Chemistry. 290: 18111-23. PMID 26060250 DOI: 10.1074/Jbc.M115.663088  1
2015 De Leon Rodriguez LM, Weidkamp AJ, Brimble MA. An update on new methods to synthesize cyclotetrapeptides. Organic & Biomolecular Chemistry. 13: 6906-21. PMID 26022908 DOI: 10.1039/C5Ob00880H  1
2015 Booe JM, Walker CS, Barwell J, Kuteyi G, Simms J, Jamaluddin MA, Warner ML, Bill RM, Harris PW, Brimble MA, Poyner DR, Hay DL, Pioszak AA. Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor. Molecular Cell. 58: 1040-52. PMID 25982113 DOI: 10.1016/J.Molcel.2015.04.018  1
2015 Papst S, Brimble MA, Evans CW, Verdon DJ, Feisst V, Dunbar PR, Tilley RD, Williams DE. Cell-targeted platinum nanoparticles and nanoparticle clusters. Organic & Biomolecular Chemistry. 13: 6567-72. PMID 25978133 DOI: 10.1039/C5Ob00822K  1
2015 Kamalov M, Harris PW, Wood JM, Brimble MA. On resin synthesis and cross-linking of collagen peptides containing the advanced glycation end-product pyrraline via Maillard condensation. Chemical Communications (Cambridge, England). 51: 9475-8. PMID 25963401 DOI: 10.1039/C5Cc03052H  1
2015 Brings S, Zhang S, Choong YS, Hogl S, Middleditch M, Kamalov M, Brimble MA, Gong D, Cooper GJ. Diabetes-induced alterations in tissue collagen and carboxymethyllysine in rat kidneys: Association with increased collagen-degrading proteinases and amelioration by Cu(II)-selective chelation. Biochimica Et Biophysica Acta. 1852: 1610-8. PMID 25900786 DOI: 10.1016/J.Bbadis.2015.04.014  1
2015 Atkinson DJ, Brimble MA. Isolation, biological activity, biosynthesis and synthetic studies towards the rubromycin family of natural products. Natural Product Reports. 32: 811-40. PMID 25798711 DOI: 10.1039/C4Np00153B  1
2015 Williams GM, Lee K, Li X, Cooper GJ, Brimble MA. Replacement of the CysA7-CysB7 disulfide bond with a 1,2,3-triazole linker causes unfolding in insulin glargine. Organic & Biomolecular Chemistry. 13: 4059-63. PMID 25731597 DOI: 10.1039/C5Ob00160A  1
2015 Hubert JG, Furkert DP, Brimble MA. Synthesis of the spirocyclic framework of sesterterpenoid natural products. The Journal of Organic Chemistry. 80: 2715-23. PMID 25658583 DOI: 10.1021/Jo502897U  1
2015 Harris PW, Brimble MA. Chemical synthesis of a polypeptide backbone derived from the primary sequence of the cancer protein NY-ESO-1 enabled by kinetically controlled ligation and pseudoprolines. Biopolymers. 104: 116-27. PMID 25656702 DOI: 10.1002/Bip.22621  1
2015 Guan J, Harris P, Brimble M, Lei Y, Lu J, Yang Y, Gunn AJ. The role for IGF-1-derived small neuropeptides as a therapeutic target for neurological disorders. Expert Opinion On Therapeutic Targets. 19: 785-93. PMID 25652713 DOI: 10.1517/14728222.2015.1010514  1
2015 Hubert JG, Furkert DP, Brimble MA. Preparation of cis-γ-hydroxycarvone derivatives for synthesis of sesterterpenoid natural products: total synthesis of phorbin A. The Journal of Organic Chemistry. 80: 2231-9. PMID 25630043 DOI: 10.1021/Jo502748S  1
2015 Kamalov M, Harris PW, Hartinger CG, Miskelly GM, Cooper GJ, Brimble MA. Physicochemical studies on the copper(II) binding by glycated collagen telopeptides. Organic & Biomolecular Chemistry. 13: 3058-63. PMID 25622575 DOI: 10.1039/C4Ob02536A  1
2015 Brimble MA, Edwards PJ, Harris PW, Norris GE, Patchett ML, Wright TH, Yang SH, Carley SE. Synthesis of the antimicrobial S-linked glycopeptide, glycocin F. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 3556-61. PMID 25607533 DOI: 10.1002/Chem.201405692  1
2015 Kaur H, Harris PW, Little PJ, Brimble MA. Total synthesis of the cyclic depsipeptide YM-280193, a platelet aggregation inhibitor. Organic Letters. 17: 492-5. PMID 25590672 DOI: 10.1021/Ol503507G  1
2015 Lee KL, Middleditch MJ, Williams GM, Brimble MA, Cooper GJ. Using mass spectrometry to detect, differentiate, and semiquantitate closely related peptide hormones in complex milieu: measurement of IGF-II and vesiculin. Endocrinology. 156: 1194-9. PMID 25545381 DOI: 10.1210/En.2014-1593  1
2015 Harris PW, Squire C, Young PG, Brimble MA. Chemical synthesis of γ-secretase activating protein using pseudoglutamines as ligation sites. Biopolymers. 104: 37-45. PMID 25523549 DOI: 10.1002/Bip.22600  1
2015 Wadsworth AD, Naysmith BJ, Brimble MA. A review of the synthesis of α-carbolines. European Journal of Medicinal Chemistry. 97: 816-29. PMID 25499235 DOI: 10.1016/J.Ejmech.2014.11.038  1
2015 Medini K, Harris PW, Hards K, Dingley AJ, Cook GM, Brimble MA. Chemical synthesis of a pore-forming antimicrobial protein, caenopore-5, by using native chemical ligation at a glu-cys site. Chembiochem : a European Journal of Chemical Biology. 16: 328-36. PMID 25425108 DOI: 10.1002/Cbic.201402513  1
2015 Mellor KM, Brimble MA, Delbridge LM. Glucose as an agent of post-translational modification in diabetes--New cardiac epigenetic insights. Life Sciences. 129: 48-53. PMID 24699006 DOI: 10.1016/J.Lfs.2014.03.020  1
2015 Dolan C, Naysmith B, Hinkley SFR, Sims IM, Brimble MA, Williams DE, Jin J. Synthesis of novel triazole-containing phosphonate polymers Australian Journal of Chemistry. 68: 680-686. DOI: 10.1071/Ch14513  1
2015 McIntosh JD, Brimble MA, Brooks AES, Dunbar PR, Kowalczyk R, Tomabechi Y, Fairbanks AJ. Convergent chemo-enzymatic synthesis of mannosylated glycopeptides; targeting of putative vaccine candidates to antigen presenting cells Chemical Science. 6: 4636-4642. DOI: 10.1039/c5sc00952a  1
2015 Anderson RJ, Compton BJ, Tang CW, Authier-Hall A, Hayman CM, Swinerd GW, Kowalczyk R, Harris P, Brimble MA, Larsen DS, Gasser O, Weinkove R, Hermans IF, Painter GF. NKT cell-dependent glycolipid-peptide vaccines with potent anti-tumour activity Chemical Science. 6: 5120-5127. DOI: 10.1039/c4sc03599b  1
2015 Robinson E, Leung E, Matuszek AM, Krogsgaard-Larsen N, Furkert DP, Brimble MA, Richardson A, Reynisson J. Virtual screening for novel Atg5-Atg16 complex inhibitors for autophagy modulation Medchemcomm. 6: 239-246. DOI: 10.1039/C4Md00420E  1
2015 Sparrow KJ, Carley S, Söhnel T, Barker D, Brimble MA. Studies towards development of asymmetric double-Mannich reactions of chiral 2-oxocyclohexanecarboxylate derivatives with bis(aminol)ethers Tetrahedron. 71: 2210-2221. DOI: 10.1016/J.Tet.2015.02.083  1
2015 Atkinson DJ, Furkert DP, Brimble MA. Synthesis of the carbon skeleton of the griseorhodins Tetrahedron. 71: 91-101. DOI: 10.1016/J.Tet.2014.11.030  1
2015 Hassan NPS, Naysmith BJ, Sperry J, Brimble MA. Formal synthesis of nanaomycin D via a Hauser-Kraus annulation using a chiral enone-lactone Tetrahedron. 71: 7137-7143. DOI: 10.1016/J.Tet.2014.09.014  1
2015 Hume PA, Furkert DP, Brimble MA. Total Synthesis of the Fungal Metabolite Virgatolide B Strategies and Tactics in Organic Synthesis. 11: 119-150. DOI: 10.1016/B978-0-08-100023-6.00005-1  1
2015 Stach M, Weidkamp AJ, Yang SH, Hung KY, Furkert DP, Harris PWR, Smaill JB, Patterson AV, Brimble MA. Improved Strategy for the Synthesis of the Anticancer Agent Culicinin D European Journal of Organic Chemistry. 2015: 6341-6350. DOI: 10.1002/Ejoc.201500872  1
2015 Stubbing LA, Lott JS, Dawes SS, Furkert DP, Brimble MA. Synthesis of DOHNAA, a Mycobacterium tuberculosis Cholesterol CD Ring Catabolite and FadD3 Substrate European Journal of Organic Chemistry. 2015: 6075-6083. DOI: 10.1002/Ejoc.201500698  1
2014 Son SJ, Harris PW, Squire CJ, Baker EN, Kent SB, Brimble MA. Total Chemical Synthesis of an Orf Virus Protein, ORFV002, an Inhibitor of the Master Gene Regulator NF-κB. Biopolymers. 102: 137-44. PMID 26820014 DOI: 10.1002/Bip.22445  1
2014 Wadsworth AD, Furkert DP, Brimble MA. Total synthesis of the macrocyclic N-Methyl enamides palmyrolide A and 2S-sanctolide A. The Journal of Organic Chemistry. 79: 11179-93. PMID 25369466 DOI: 10.1021/Jo502238R  1
2014 Young Jeong J, Sperry J, Taylor JA, Brimble MA. Synthesis and evaluation of 9-deoxy analogues of (-)-thysanone, an inhibitor of HRV 3C protease. European Journal of Medicinal Chemistry. 87: 220-7. PMID 25259514 DOI: 10.1016/J.Ejmech.2014.09.063  1
2014 Lim D, Brimble MA, Kowalczyk R, Watson AJ, Fairbanks AJ. Protecting-group-free one-pot synthesis of glycoconjugates directly from reducing sugars. Angewandte Chemie (International Ed. in English). 53: 11907-11. PMID 25199905 DOI: 10.1002/Anie.201406694  1
2014 Noisier AF, Brimble MA. C-H functionalization in the synthesis of amino acids and peptides. Chemical Reviews. 114: 8775-806. PMID 25144592 DOI: 10.1021/Cr500200X  1
2014 Quach R, F Chorley D, Brimble MA. Recent developments in transition metal-catalysed spiroketalisation. Organic & Biomolecular Chemistry. 12: 7423-32. PMID 25137016 DOI: 10.1039/C4Ob01325E  1
2014 Kowalczyk R, Brimble MA, Tomabechi Y, Fairbanks AJ, Fletcher M, Hay DL. Convergent chemoenzymatic synthesis of a library of glycosylated analogues of pramlintide: structure-activity relationships for amylin receptor agonism. Organic & Biomolecular Chemistry. 12: 8142-51. PMID 25030939 DOI: 10.1039/C4Ob01208A  1
2014 Brimble MA, Hassan NP, Naysmith BJ, Sperry J. Toward an asymmetric synthesis of the dimeric pyranonaphthoquinone antibiotic crisamicin A. The Journal of Organic Chemistry. 79: 7169-78. PMID 25029027 DOI: 10.1021/Jo501344C  1
2014 Kowalczyk R, Yang SH, Brimble MA, Callon KE, Watson M, Park YE, Cornish J. Synthesis of truncated analogues of preptin-(1–16), and investigation of their ability to stimulate osteoblast proliferation. Bioorganic & Medicinal Chemistry. 22: 3565-72. PMID 24932835 DOI: 10.1016/J.Bmc.2014.05.026  1
2014 Young PG, Proft T, Harris PW, Brimble MA, Baker EN. Structure and activity of Streptococcus pyogenes SipA: a signal peptidase-like protein essential for pilus polymerisation. Plos One. 9: e99135. PMID 24911348 DOI: 10.1371/Journal.Pone.0099135  1
2014 Hume PA, Furkert DP, Brimble MA. Total synthesis of virgatolide B via exploitation of intramolecular hydrogen bonding. The Journal of Organic Chemistry. 79: 5269-81. PMID 24836848 DOI: 10.1021/Jo5008527  1
2014 Harris PW, Hampe L, Radjainia M, Brimble MA, Mitra AK. An investigation of the role of the adiponectin variable domain on the stability of the collagen-like domain. Biopolymers. 101: 313-21. PMID 24752567 DOI: 10.1002/Bip.22501  1
2014 Kamalov M, Harris PW, Cooper GJ, Brimble MA. Site-specific cross-linking of collagen peptides by lysyl advanced glycation endproducts. Chemical Communications (Cambridge, England). 50: 4944-6. PMID 24705519 DOI: 10.1039/C4Cc02003K  1
2014 Yeung H, Harris PW, Squire CJ, Baker EN, Brimble MA. Preparation of truncated orf virus entry fusion complex proteins by chemical synthesis. Journal of Peptide Science : An Official Publication of the European Peptide Society. 20: 398-405. PMID 24652714 DOI: 10.1002/Psc.2627  1
2014 Harris PW, Yang SH, Molina A, López G, Middleditch M, Brimble MA. Plant antimicrobial peptides snakin-1 and snakin-2: chemical synthesis and insights into the disulfide connectivity. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 5102-10. PMID 24644073 DOI: 10.1002/Chem.201303207  1
2014 Conole D, Beck TM, Jay-Smith M, Tingle MD, Eason CT, Brimble MA, Rennison D. Synthesis and methemoglobinemia-inducing properties of benzocaine isosteres designed as humane rodenticides. Bioorganic & Medicinal Chemistry. 22: 2220-35. PMID 24602400 DOI: 10.1016/J.Bmc.2014.02.013  1
2014 Harris PW, Kowalczyk R, Yang SH, Williams GM, Brimble MA. An important side reaction using the thiol, 3,6-dioxa-1,8-octanedithiol (DODT), in 9-fluorenylmethoxycarbonyl-based solid phase peptide synthesis. Journal of Peptide Science : An Official Publication of the European Peptide Society. 20: 186-90. PMID 24353069 DOI: 10.1002/Psc.2595  1
2014 Ding XB, Furkert DP, Capon RJ, Brimble MA. Total synthesis of heronapyrrole C. Organic Letters. 16: 378-81. PMID 24351092 DOI: 10.1021/Ol403246J  1
2014 Schünemann K, Furkert DP, Choi EC, Connelly S, Fraser JD, Sperry J, Brimble MA. Synthesis of the 2-methylene analogue of the HRV 3C protease inhibitor thysanone (2-carbathysanone). Organic & Biomolecular Chemistry. 12: 905-12. PMID 24346589 DOI: 10.1039/C3Ob41951G  1
2014 Hay DL, Harris PW, Kowalczyk R, Brimble MA, Rathbone DL, Barwell J, Conner AC, Poyner DR. Structure-activity relationships of the N-terminus of calcitonin gene-related peptide: key roles of alanine-5 and threonine-6 in receptor activation. British Journal of Pharmacology. 171: 415-26. PMID 24125506 DOI: 10.1111/Bph.12464  1
2014 Yin N, Brimble MA, Harris PW, Wen J. Enhancing the Oral Bioavailability of Peptide Drugs by using ChemicalModification and Other Approaches Medicinal Chemistry. 4: 763-769. DOI: 10.4172/2161-0444.1000227  1
2014 Wilcox C, Jin J, Charville H, Swift S, To T, Kilmartin PA, Evans CW, Cooney R, Brimble M. Synthesis of a novel polyaniline glycopolymer and its lectin binding studies Australian Journal of Chemistry. 67: 562-569. DOI: 10.1071/Ch13452  1
2014 Harris P, Molenaar GT, Amso Z, Savage GP, Brimble MA. An Efficient Fmoc Solid-Phase Synthesis of an Amphiphile of the Neuroprotective Agent Glycyl-prolyl-glutamic Acid Synlett. DOI: 10.1055/S-0034-1378539  1
2014 Kamalov M, Yang S, Harris PWR, Cooper GJS, Brimble MA. Expedient synthesis of peptides containing Nε- carboxymethyllysine Synlett. 25: 1835-1838. DOI: 10.1055/S-0033-1378305  1
2014 Schünemann K, Furkert DP, Connelly S, Fraser JD, Sperry J, Brimble MA. Iridium-catalysed C-H borylation facilitates a total synthesis of the HRV 3C protease inhibitor (±)-thysanone Synlett. 25: 556-558. DOI: 10.1055/S-0033-1340495  1
2014 Kaur H, Heapy AM, Kowalczyk R, Amso Z, Watson M, Cornish J, Brimble MA. Synthesis and biological evaluation of the osteoblast proliferating cyclic peptides dianthins G and H Tetrahedron. 70: 7788-7794. DOI: 10.1016/J.Tet.2014.04.035  1
2014 Naysmith BJ, Furkert D, Brimble MA. Synthesis of highly substituted pyranonaphthalene spiroketals related to the griseusins using a Hauser-Kraus annulation strategy Tetrahedron. 70: 1199-1206. DOI: 10.1016/J.Tet.2013.12.066  1
2014 Finch OC, Furkert DP, Brimble MA. Synthesis of the spiroacetal core of the cephalosporolide family of natural products Tetrahedron. 70: 590-596. DOI: 10.1016/J.Tet.2013.12.012  1
2014 Papst S, Brimble MA, Tilley RD, Williams DE. One-pot synthesis of functionalized noble metal nanoparticles using a rationally designed phosphopeptide Particle and Particle Systems Characterization. 31: 971-975. DOI: 10.1002/Ppsc.201300381  1
2014 Drouet F, Noisier AFM, Harris CS, Furkert DP, Brimble MA. A Convenient Method for the Asymmetric Synthesis of Fluorinated α-Amino Acids from Alcohols (Eur. J. Org. Chem. 6/2014) European Journal of Organic Chemistry. 2014: n/a-n/a. DOI: 10.1002/Ejoc.201490012  0.01
2014 Furkert DP, Breitenbach B, Juen L, Sroka I, Pantin M, Brimble MA. Nonsymmetrical azocarbonamide carboxylates as effective Mitsunobu reagents European Journal of Organic Chemistry. 2014: 7806-7809. DOI: 10.1002/Ejoc.201403152  1
2014 Geng HM, Stubbing LA, Li-yang Chen J, Furkert DP, Brimble MA. Synthesis of the revised structure of acortatarin A European Journal of Organic Chemistry. DOI: 10.1002/Ejoc.201403000  1
2014 Drouet F, Noisier AFM, Harris CS, Furkert DP, Brimble MA. A convenient method for the asymmetric synthesis of fluorinated α-amino acids from alcohols European Journal of Organic Chemistry. 2014: 1195-1201. DOI: 10.1002/Ejoc.201301718  1
2014 Yuen TY, Eaton SE, Woods TM, Furkert DP, Choi KW, Brimble MA. A Maillard approach to 2-formylpyrroles: Synthesis of magnolamide, lobechine and funebral European Journal of Organic Chemistry. 2014: 1431-1437. DOI: 10.1002/Ejoc.201301639  1
2014 Schünemann K, Furkert DP, Connelly S, Fraser JD, Sperry J, Brimble MA. Synthesis and biological evaluation of 7-deoxy analogues of the human rhinovirus 3c protease inhibitor thysanone European Journal of Organic Chemistry. 2014: 122-128. DOI: 10.1002/Ejoc.201301515  1
2014 Son SJ, Harris PWR, Squire CJ, Baker EN, Kent SBH, Brimble MA. Total chemical synthesis of an Orf virus protein, ORFV002, an inhibitor of the master gene regulator NF-κB Biopolymers - Peptide Science Section. 102: 137-144. DOI: 10.1002/bip.22445  1
2013 Heapy AM, Patterson AV, Smaill JB, Jamieson SM, Guise CP, Sperry J, Hume PA, Rathwell K, Brimble MA. Synthesis and cytotoxicity of pyranonaphthoquinone natural product analogues under bioreductive conditions. Bioorganic & Medicinal Chemistry. 21: 7971-80. PMID 24436995 DOI: 10.1016/J.Bmc.2013.09.052  1
2013 Rennison D, Conole D, Tingle MD, Yang J, Eason CT, Brimble MA. Synthesis and methemoglobinemia-inducing properties of analogues of para-aminopropiophenone designed as humane rodenticides. Bioorganic & Medicinal Chemistry Letters. 23: 6629-35. PMID 24210502 DOI: 10.1016/J.Bmcl.2013.10.046  1
2013 Johannes M, Brimble MA. Synthesis of an azido precursor to (2S,5R)-5-hydroxylysine using an asymmetric organocatalytic chlorination/reduction sequence. The Journal of Organic Chemistry. 78: 12809-13. PMID 24175670 DOI: 10.1021/Jo402220S  1
2013 Hume PA, Furkert DP, Brimble MA. Total synthesis of virgatolide B. Organic Letters. 15: 4588-91. PMID 23957570 DOI: 10.1021/Ol402191T  1
2013 Wright TH, Brooks AE, Didsbury AJ, MacIntosh JD, Williams GM, Harris PW, Dunbar PR, Brimble MA. Direct peptide lipidation through thiol-ene coupling enables rapid synthesis and evaluation of self-adjuvanting vaccine candidates. Angewandte Chemie (International Ed. in English). 52: 10616-9. PMID 23939951 DOI: 10.1002/Anie.201305620  1
2013 Rennison D, Laita O, Conole D, Jay-Smith M, Knauf J, Bova S, Cavalli M, Hopkins B, Linthicum DS, Brimble MA. Prodrugs of N-dicarboximide derivatives of the rat selective toxicant norbormide. Bioorganic & Medicinal Chemistry. 21: 5886-99. PMID 23920483 DOI: 10.1016/J.Bmc.2013.06.071  1
2013 Noisier AF, Harris CS, Brimble MA. Novel preparation of chiral α-amino acids using the Mitsunobu-Tsunoda reaction. Chemical Communications (Cambridge, England). 49: 7744-6. PMID 23877629 DOI: 10.1039/C3Cc44717K  1
2013 Aitken HR, Furkert DP, Hubert JG, Wood JM, Brimble MA. Enantioselective access to benzannulated spiroketals using a chiral sulfoxide auxiliary. Organic & Biomolecular Chemistry. 11: 5147-55. PMID 23817587 DOI: 10.1039/C3Ob41065J  1
2013 Yang SH, Wojnar JM, Harris PW, DeVries AL, Evans CW, Brimble MA. Chemical synthesis of a masked analogue of the fish antifreeze potentiating protein (AFPP). Organic & Biomolecular Chemistry. 11: 4935-42. PMID 23788006 DOI: 10.1039/C3Ob41066H  1
2013 Bobby R, Medini K, Neudecker P, Lee TV, Brimble MA, McDonald FJ, Lott JS, Dingley AJ. Structure and dynamics of human Nedd4-1 WW3 in complex with the αENaC PY motif. Biochimica Et Biophysica Acta. 1834: 1632-41. PMID 23665454 DOI: 10.1016/J.Bbapap.2013.04.031  1
2013 Woods TM, Cooper GJ, Brimble MA. Synthesis of stable isotope-labelled monolysyl advanced glycation endproducts. Amino Acids. 45: 319-25. PMID 23588492 DOI: 10.1007/S00726-013-1498-9  1
2013 Papst S, Cheong S, Banholzer MJ, Brimble MA, Williams DE, Tilley RD. One-pot synthesis of water soluble iron nanoparticles using rationally-designed peptides and ligand release. Chemical Communications (Cambridge, England). 49: 4540-2. PMID 23576141 DOI: 10.1039/C3Cc41751D  1
2013 Naysmith BJ, Brimble MA. Synthesis of the griseusin B framework via a one-pot annulation-methylation-double deprotection-spirocyclization sequence. Organic Letters. 15: 2006-9. PMID 23560611 DOI: 10.1021/Ol400686F  1
2013 Williams GM, Cooper GJ, Lee K, Whiting L, Brimble MA. Synthesis of the IGF-II-like hormone vesiculin using regioselective formation of disulfide bonds. Organic & Biomolecular Chemistry. 11: 3145-50. PMID 23538787 DOI: 10.1039/C3Ob40322J  1
2013 Harris PW, Brimble MA. A comparison of Boc and Fmoc SPPS strategies for the preparation of C-terminal peptide α-thiolesters: NY-ESO-1 (39) Cys-(68) Ala-COSR. Biopolymers. 100: 356-65. PMID 23444272 DOI: 10.1002/Bip.22223  1
2013 Kueh JT, Choi KW, Williams GM, Moehle K, Bacsa B, Robinson JA, Brimble MA. Synthesis of a 6,6-spiroketal amino acid and its incorporation into a peptide turn sequence using solid-phase peptide synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 3807-11. PMID 23424080 DOI: 10.1002/Chem.201204546  1
2013 Watkins HA, Au M, Bobby R, Archbold JK, Abdul-Manan N, Moore JM, Middleditch MJ, Williams GM, Brimble MA, Dingley AJ, Hay DL. Identification of key residues involved in adrenomedullin binding to the AM1 receptor British Journal of Pharmacology. 169: 143-155. PMID 23351143 DOI: 10.1111/Bph.12118  1
2013 Kim UB, Furkert DP, Brimble MA. Total synthesis of chaetoquadrins A-C. Organic Letters. 15: 658-61. PMID 23327616 DOI: 10.1021/Ol303482K  1
2013 Stubbing LA, Savage GP, Brimble MA. N-alkylsulfonylimines as dipolarophiles in cycloaddition reactions. Chemistry, An Asian Journal. 8: 42-8. PMID 22945869 DOI: 10.1002/Asia.201200584  1
2013 Kuntworbe N, Alany RG, Brimble M, Al-Kassas R. Determination of pKa and forced degradation of the indoloquinoline antimalarial compound cryptolepine hydrochloride. Pharmaceutical Development and Technology. 18: 866-76. PMID 22436019 DOI: 10.3109/10837450.2012.668554  0.01
2013 Brimble MA, Black DS, Hartshorn R, Rauter AP, Sha CK, Sydnes LK. Rules for abbreviation of protecting groups (IUPAC technical report) Pure and Applied Chemistry. 85: 307-313. DOI: 10.1351/Pac-Rep-12-07-12  1
2013 Bobby R, Medini K, Neudecker P, Lee V, MacDonald F, Brimble M, Lott JS, Dingley A. Structure and dynamics of a human Nedd4 WW domain-ENaC complex Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr18971  1
2013 Yuen TY, Ng YP, Ip FCF, Chen JLY, Atkinson DJ, Sperry J, Ip NY, Brimble MA. Telomerase inhibition studies of novel spiroketal-containing rubromycin derivatives Australian Journal of Chemistry. 66: 530-533. DOI: 10.1071/Ch13035  1
2013 Bridewell DJA, Sperry J, Smith JR, Kosim-Satyaputra P, Ching LM, Jamie JF, Brimble MA. Natural product-inspired pyranonaphthoquinone inhibitors of indoleamine 2,3-dioxygenase-1 (IDO-1)* Australian Journal of Chemistry. 66: 40-49. DOI: 10.1071/Ch12393  1
2013 Son SJ, Brimble MA, Yang S, Harris PWR, Reddingius T, Muir BW, Hutt OE, Waddington L, Guan J, Savage GP. Synthesis and self-assembly of a peptide-amphiphile as a drug delivery vehicle Australian Journal of Chemistry. 66: 23-29. DOI: 10.1071/Ch12347  1
2013 Wright TH, Brooks AES, Didsbury AJ, McIntosh JD, Burkert K, Yeung H, Williams GM, Dunbar PR, Brimble MA. An improved method for the synthesis of lipopeptide TLR2-agonists using click chemistry Synlett. 24: 1835-1841. DOI: 10.1055/S-0033-1339349  1
2013 Heapy AM, Dragunow M, Brimble MA. Synthesis of the cysteine protease inhibitors CPI-2081a and CPI-2081b using a controlled SPPS byproduct forming reaction Synlett. 24: 1818-1824. DOI: 10.1055/S-0033-1339347  1
2013 Kim UB, Dalebrook AF, Furkert DP, Brimble MA. Total synthesis of chaetoquadrins H and i Synlett. 24: 723-726. DOI: 10.1055/S-0032-1318333  1
2013 Charville H, Jin J, Evans CW, Brimble MA, Williams DE. The synthesis and lectin-binding properties of novel mannose-functionalised polymers Rsc Advances. 3: 15435-15441. DOI: 10.1039/C3Ra42781A  1
2013 Malmström J, Nieuwoudt MK, Strover LT, Hackett A, Laita O, Brimble MA, Williams DE, Travas-Sejdic J. Grafting from poly(3,4-ethylenedioxythiophene): A simple route to versatile electrically addressable surfaces Macromolecules. 46: 4955-4965. DOI: 10.1021/Ma400803J  1
2013 Aitken HRM, Johannes M, Loomes KM, Brimble MA. Synthesis of leptosin, a glycoside isolated from mānuka honey Tetrahedron Letters. 54. DOI: 10.1016/J.Tetlet.2013.10.042  1
2013 Quach R, Furkert DP, Brimble MA. Synthesis of benzannulated spiroacetals using chiral gold-phosphine complexes and chiral anions Tetrahedron Letters. 54: 5865-5868. DOI: 10.1016/J.Tetlet.2013.08.077  1
2013 Strover LT, Malmström J, Laita O, Reynisson J, Aydemir N, Nieuwoudt MK, Williams DE, Dunbar PR, Brimble MA, Travas-Sejdic J. A new precursor for conducting polymer-based brush interfaces with electroactivity in aqueous solution Polymer (United Kingdom). 54: 1305-1317. DOI: 10.1016/J.Polymer.2012.11.083  1
2013 Hume PA, Brimble MA, Reynisson J. DNA adduct formation of mitomycin C. A test case for DFT calculations on model systems Computational and Theoretical Chemistry. 1005: 9-15. DOI: 10.1016/J.Comptc.2012.10.022  1
2013 Harris PWR, Kowalczyk R, Hay DL, Brimble MA. A single pseudoproline and microwave solid phase peptide synthesis facilitates an efficient synthesis of human amylin 1-37 International Journal of Peptide Research and Therapeutics. 19: 147-155. DOI: 10.1007/S10989-012-9325-9  1
2013 Wojnar JM, Lee DJ, Evans CW, Mandal K, Kent SBH, Brimble MA. Neoglycoprotein Synthesis Using the Copper-Catalyzed Azide-Alkyne Click Reaction and Native Chemical Ligation Click Chemistry in Glycoscience: New Developments and Strategies. 251-270. DOI: 10.1002/9781118526996.ch10  1
2012 Brimble MA, Haym I, Sperry J, Furkert DP. Synthesis of the tetracyclic core of berkelic acid using gold(I)-catalyzed hydroarylation and oxidative radical cyclizations. Organic Letters. 14: 5820-3. PMID 23186011 DOI: 10.1021/Ol302536J  1
2012 Hung KY, Harris PW, Brimble MA. Synthesis of the peptaibol framework of the anticancer agent culicinin D: stereochemical assignment of the AHMOD moiety. Organic Letters. 14: 5784-7. PMID 23126283 DOI: 10.1021/Ol302852Q  1
2012 Woods TM, Kamalov M, Harris PW, Cooper GJ, Brimble M. Synthesis of monolysyl advanced glycation endproducts and their incorporation into collagen model peptides. Organic Letters. 14: 5740-3. PMID 23116133 DOI: 10.1021/Ol302745F  1
2012 Wadsworth AD, Furkert DP, Sperry J, Brimble MA. Total synthesis of the initially reported and revised structures of the neuroprotective agent palmyrolide A. Organic Letters. 14: 5374-7. PMID 23046111 DOI: 10.1021/Ol3025956  1
2012 Yuen TY, Brimble MA. Total synthesis of 7',8'-dihydroaigialospirol. Organic Letters. 14: 5154-7. PMID 23016996 DOI: 10.1021/Ol302498V  1
2012 Kowalczyk R, Brimble MA, Callon KE, Watson M, Cornish J. How to blast osteoblasts? Novel dicarba analogues of amylin-(1-8) to treat osteoporosis. Bioorganic & Medicinal Chemistry. 20: 6011-8. PMID 22998786 DOI: 10.1016/J.Bmc.2012.08.053  1
2012 Haym I, Brimble MA. The Kulinkovich hydroxycyclopropanation reaction in natural product synthesis. Organic & Biomolecular Chemistry. 10: 7649-65. PMID 22886040 DOI: 10.1039/C2Ob26082D  1
2012 Papst S, Noisier AF, Brimble MA, Yang Y, Krissansen GW. Synthesis and biological evaluation of tyrosine modified analogues of the α4β7 integrin inhibitor biotin-R₈ERY. Bioorganic & Medicinal Chemistry. 20: 5139-49. PMID 22877871 DOI: 10.1016/J.Bmc.2012.07.010  1
2012 Lee DJ, Yang SH, Williams GM, Brimble MA. Synthesis of multivalent neoglyconjugates of MUC1 by the conjugation of carbohydrate-centered, triazole-linked glycoclusters to MUC1 peptides using click chemistry. The Journal of Organic Chemistry. 77: 7564-71. PMID 22876975 DOI: 10.1021/Jo3013435  1
2012 Liu Z, Walters BJ, Owen T, Brimble MA, Steigelman KA, Zhang L, Mellado Lagarde MM, Valentine MB, Yu Y, Cox BC, Zuo J. Regulation of p27Kip1 by Sox2 maintains quiescence of inner pillar cells in the murine auditory sensory epithelium. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10530-40. PMID 22855803 DOI: 10.1523/Jneurosci.0686-12.2012  1
2012 Harris PW, Lee DJ, Brimble MA. A slow gradient approach for the purification of synthetic polypeptides by reversed phase high performance liquid chromatography. Journal of Peptide Science : An Official Publication of the European Peptide Society. 18: 549-55. PMID 22833387 DOI: 10.1002/Psc.2432  1
2012 Schünemann K, Connelly S, Kowalczyk R, Sperry J, Wilson IA, Fraser JD, Brimble MA. A simple solid phase, peptide-based fluorescent assay for the efficient and universal screening of HRV 3C protease inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 5018-24. PMID 22763202 DOI: 10.1016/J.Bmcl.2012.06.015  1
2012 Rennison D, Laita O, Bova S, Cavalli M, Hopkins B, Linthicum DS, Brimble MA. Design and synthesis of prodrugs of the rat selective toxicant norbormide. Bioorganic & Medicinal Chemistry. 20: 3997-4011. PMID 22658693 DOI: 10.1016/J.Bmc.2012.05.014  1
2012 Radjainia M, Huang B, Bai B, Schmitz M, Yang SH, Harris PW, Griffin MD, Brimble MA, Wang Y, Mitra AK. A highly conserved tryptophan in the N-terminal variable domain regulates disulfide bond formation and oligomeric assembly of adiponectin. The Febs Journal. 279: 2495-507. PMID 22583869 DOI: 10.1111/J.1742-4658.2012.08630.X  1
2012 Papst S, Noisier A, Brimble MA, Yang Y, Krissansen GW. Tyrosine modified analogues of the α4β7 integrin inhibitor biotin-R₈ERY prepared via Click Chemistry: synthesis and biological evaluation. Bioorganic & Medicinal Chemistry. 20: 2638-44. PMID 22421276 DOI: 10.1016/J.Bmc.2012.02.035  1
2012 Kowalczyk R, Harris PW, Brimble MA, Callon KE, Watson M, Cornish J. Synthesis and evaluation of disulfide bond mimetics of amylin-(1-8) as agents to treat osteoporosis. Bioorganic & Medicinal Chemistry. 20: 2661-8. PMID 22398258 DOI: 10.1016/J.Bmc.2012.02.030  1
2012 Heapy AM, Williams GM, Fraser JD, Brimble MA. Synthesis of a dicarba analogue of human β-defensin-1 using a combined ring closing metathesis--native chemical ligation strategy. Organic Letters. 14: 878-81. PMID 22239540 DOI: 10.1021/Ol203407Z  1
2012 Kueh JT, Choi KW, Brimble MA. Enantioselective synthesis of C-linked spiroacetal-triazoles as privileged natural product-like scaffolds. Organic & Biomolecular Chemistry. 10: 5993-6002. PMID 22237938 DOI: 10.1039/C2Ob06802H  1
2012 Herbert KR, Williams GM, Cooper GJ, Brimble MA. Synthesis of glycosylated 5-hydroxylysine, an important amino acid present in collagen-like proteins such as adiponectin. Organic & Biomolecular Chemistry. 10: 1137-44. PMID 22218394 DOI: 10.1039/C1Ob06394D  1
2012 McLeod MC, Wilson ZE, Brimble MA. Formal synthesis of berkelic acid: a lesson in α-alkylation chemistry. The Journal of Organic Chemistry. 77: 400-16. PMID 22077770 DOI: 10.1021/Jo201988M  1
2012 Mcleod MC, Brimble MA, Rathwell DCK, Wilson ZE, Yuen TY. Synthetic approaches to [5,6]-benzannulated spiroketal natural products Pure and Applied Chemistry. 84: 1379-1390. DOI: 10.1351/Pac-Con-11-08-06  1
2012 Papst S, Noisier AFM, Brimble MA, Yang Y, Chan YC, Krissansen GW. Synthesis and SAR of a library of cell-permeable biotin-R 8ERY*peptidomimetics inhibiting 47 integrin mediated adhesion of TK-1 cells to MAdCAM -1-Fc Australian Journal of Chemistry. 65: 1349-1358. DOI: 10.1071/Ch12227  1
2012 Peltier R, Siah WR, Williams GVM, Brimble MA, Tilley RD, Williams DE. Novel phosphopeptides as surface-active agents in iron nanoparticle synthesis Australian Journal of Chemistry. 65: 680-685. DOI: 10.1071/Ch12168  1
2012 Hume PA, Brimble MA, Reynisson J. The bioreductive alkylation of DNA by kalafungin: A theoretical investigation Australian Journal of Chemistry. 65: 402-408. DOI: 10.1071/Ch12018  1
2012 Kaur H, Heapy AM, Brimble MA. Synthesis of the all-l cyclopentapeptides versicoloritides A, B, and C Synlett. 23: 2284-2288. DOI: 10.1055/S-0032-1316994  1
2012 Yeung H, Lee DJ, Williams GM, Harris PWR, Dunbar RP, Brimble MA. A method for the generation of Pamys-based lipopeptide mimics via CuAAC click chemistry Synlett. 23: 1617-1620. DOI: 10.1055/S-0031-1291148  1
2012 Geng H, Chen JY, Furkert D, Jiang S, Brimble MA. A convergent synthesis of the 2-formylpyrrole spiroketal natural product acortatarin A Synlett. 23: 855-858. DOI: 10.1055/S-0031-1290508  1
2012 Chorley DF, Chen JLY, Furkert DP, Sperry J, Brimble MA. Total synthesis of danshenspiroketallactone Synlett. 128-130. DOI: 10.1055/S-0031-1290082  1
2012 Kaur H, Heapy AM, Brimble MA. Synthesis of the antifungal cyclic peptides tunicyclins C and D Synlett. 275-277. DOI: 10.1055/S-0031-1290071  1
2012 Dimitrov I, Furkert DP, Fraser JD, Radcliff FJ, Finch O, Brimble MA. Synthesis and anti-Helicobacter pylori activity of analogues of spirolaxine methyl ether Medchemcomm. 3: 938-943. DOI: 10.1039/C2Md00314G  1
2012 Evans CW, Hellman L, Middleditch M, Wojnar JM, Brimble MA, Devries AL. Synthesis and recycling of antifreeze glycoproteins in polar fishes Antarctic Science. 24: 259-268. DOI: 10.1017/S0954102012000119  1
2012 Hume P, Furkert DP, Brimble MA. Regioselective iridium(I)-catalysed remote borylation of oxygenated naphthalenes Tetrahedron Letters. 53: 3771-3773. DOI: 10.1016/J.Tetlet.2012.05.040  1
2012 Stubbing LA, Li FF, Furkert DP, Caprio VE, Brimble MA. Access to 2-alkyl chromanones via a conjugate addition approach Tetrahedron. 68: 6948-6956. DOI: 10.1016/J.Tet.2012.05.115  1
2012 Goodall KJ, Brimble MA, Barker D. A tandem Diels-Alder/Mannich approach to the synthesis of AE and ABE ring analogues of Delphinium alkaloids Tetrahedron. 68: 5759-5778. DOI: 10.1016/J.Tet.2012.05.037  1
2012 Sparrow K, Barker D, Brimble MA. An efficient synthesis of 3-alkyl-1,5,3-dioxazepanes and their use as electrophiles in double-Mannich reactions Tetrahedron. 68: 1017-1028. DOI: 10.1016/J.Tet.2011.11.090  1
2012 Harris PWR, Brimble MA. The chemical synthesis of the collagenous domain of the hormone adiponectin International Journal of Peptide Research and Therapeutics. 18: 63-70. DOI: 10.1007/S10989-011-9279-3  1
2012 Evans CW, Williams DE, Vacchi M, Brimble MA, DeVries AL. Metabolic and behavioural adaptations during early development of the Antarctic silverfish, Pleuragramma antarcticum Polar Biology. 35: 891-898. DOI: 10.1007/S00300-011-1134-7  1
2011 Chen JL, Brimble MA. Synthesis of the bis-spiroacetal core of the antimitotic agent spirastrellolide B. The Journal of Organic Chemistry. 76: 9417-28. PMID 21995770 DOI: 10.1021/Jo201729T  1
2011 Yang SH, Lee DJ, Brimble MA. Synthesis of an NDPK phosphocarrier domain peptide containing a novel triazolylalanine analogue of phosphohistidine using click chemistry. Organic Letters. 13: 5604-7. PMID 21939187 DOI: 10.1021/Ol202333U  1
2011 McLeod MC, Wilson ZE, Brimble MA. An enantioselective formal synthesis of berkelic acid. Organic Letters. 13: 5382-5. PMID 21916400 DOI: 10.1021/Ol202265G  1
2011 Zulian A, Sileikytė J, Petronilli V, Bova S, Dabbeni-Sala F, Cargnelli G, Rennison D, Brimble MA, Hopkins B, Bernardi P, Ricchelli F. The translocator protein (peripheral benzodiazepine receptor) mediates rat-selective activation of the mitochondrial permeability transition by norbormide. Biochimica Et Biophysica Acta. 1807: 1600-5. PMID 21889488 DOI: 10.1016/J.Bbabio.2011.08.007  1
2011 Yuen TY, Yang SH, Brimble MA. Total synthesis of paecilospirone. Angewandte Chemie (International Ed. in English). 50: 8350-3. PMID 21780263 DOI: 10.1002/Anie.201103117  1
2011 Kaur H, Heapy AM, Brimble MA. The synthesis of dehydrotryptophan and dehydrotryptophan-containing peptides. Organic & Biomolecular Chemistry. 9: 5897-907. PMID 21743891 DOI: 10.1039/C1Ob05777D  1
2011 Hume PA, Sperry J, Brimble MA. Enantioselective synthesis of pyranonaphthoquinone antibiotics using a CBS reduction/cross-metathesis/oxa-Michael strategy. Organic & Biomolecular Chemistry. 9: 5423-30. PMID 21655576 DOI: 10.1039/C1Ob05595J  1
2011 Lee DJ, Harris PW, Brimble MA. Synthesis of MUC1 Neoglycopeptides using efficient microwave-enhanced chaotrope-assisted click chemistry. Organic & Biomolecular Chemistry. 9: 1621-6. PMID 21249263 DOI: 10.1039/C0Ob01043J  1
2011 Hung KY, Harris PW, Heapy AM, Brimble MA. Synthesis and assignment of stereochemistry of the antibacterial cyclic peptide xenematide. Organic & Biomolecular Chemistry. 9: 236-42. PMID 20949214 DOI: 10.1039/C0Ob00315H  1
2011 Guéret SM, Brimble MA. Synthetic studies toward the spiroimine unit of the spirolides Pure and Applied Chemistry. 83: 425-433. DOI: 10.1351/Pac-Con-10-09-12  1
2011 Wojnar JM, Evans CW, Devries AL, Brimble MA. Synthesis of an isotopically-labelled antarctic fish antifreeze glycoprotein probe Australian Journal of Chemistry. 64: 723-731. DOI: 10.1071/Ch10464  1
2011 Jay-Smith M, Furkert DP, Sperry J, Brimble MA. Efficient synthesis of the spiroacetal core of paecilospirone via oxidative radical cyclisation Synlett. 1395-1398. DOI: 10.1055/S-0030-1260564  1
2011 Sperry J, Liu YC, Wilson ZE, Hubert JG, Brimble MA. Synthesis of benzannulated spiroketals using an oxidative radical cyclization Synthesis. 1383-1398. DOI: 10.1055/S-0030-1259981  1
2011 Atkinson DJ, Sperry J, Brimble MA. Synthesis of benzotriazole analogues of the helicobactericidal agents CJ-13,015, CJ-13,102, CJ-13,108, and CJ-13,104 using a regioselective 1,3-dipolar cycloaddition Synlett. 99-103. DOI: 10.1055/S-0030-1259081  1
2011 Chen JLY, Sperry J, Ip NY, Brimble MA. Natural products targeting telomere maintenance Medchemcomm. 2: 229-245. DOI: 10.1039/C0Md00241K  1
2011 Evans CW, Gubala V, Nooney R, Williams DE, Brimble MA, Devries AL. How do Antarctic notothenioid fishes cope with internal ice? A novel function for antifreeze glycoproteins Antarctic Science. 23: 57-64. DOI: 10.1017/S0954102010000635  1
2011 Harris PWR, Yang SH, Brimble MA. An improved procedure for the preparation of aminomethyl polystyrene resin and its use in solid phase (peptide) synthesis Tetrahedron Letters. 52: 6024-6026. DOI: 10.1016/J.Tetlet.2011.09.010  1
2011 Zhang YC, Furkert DP, Guéret SM, Lombard F, Brimble MA. Gold(I)-catalysed intramolecular hydroamination of α-quaternary alkynes: Synthetic studies towards spiroimine marine toxins Tetrahedron Letters. 52: 4896-4898. DOI: 10.1016/J.Tetlet.2011.07.048  1
2011 Sparrow K, Barker D, Brimble MA. The enantioselective synthesis of tetracyclic methyllycaconitine analogues Tetrahedron. 67: 7989-7999. DOI: 10.1016/J.Tet.2011.08.026  1
2011 Brimble MA, Finch OC, Heapy AM, Fraser JD, Furkert DP, O'Connor PD. A convergent synthesis of the [4.4]-spiroacetal-γ-lactones cephalosporolides e and F Tetrahedron. 67: 995-1001. DOI: 10.1016/J.Tet.2010.11.107  1
2011 Wilson ZE, Hubert JG, Brimble MA. A flexible approach to 6,5-benzannulated spiroketals European Journal of Organic Chemistry. 3938-3945. DOI: 10.1002/Ejoc.201100345  1
2011 Brimble MA, Miller N, Williams GM. Recent Developments in Neoglycopeptide Synthesis Amino Acids, Peptides and Proteins in Organic Chemistry. 4: 359-391. DOI: 10.1002/9783527631827.ch11  1
2010 Guéret SM, Boyd PD, Brimble MA. (1R,6R,13R,18R)-(Z,Z)-1,18-Bis[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-3,16-dimethyl-ene-8,20-diaza-dispiro-[5.6.5.6]tetra-cosa-7,19-diene. Acta Crystallographica. Section E, Structure Reports Online. 66: o1778-9. PMID 21587991 DOI: 10.1107/S1600536810023998  1
2010 Hung KY, Harris PW, Brimble MA. Synthesis of methyl N-Boc-(2S,4R)-4-methylpipecolate. The Journal of Organic Chemistry. 75: 8728-31. PMID 21090804 DOI: 10.1021/Jo102038Q  1
2010 Guéret SM, Furkert DP, Brimble MA. Synthesis of a functionalized 7,6-bicyclic spiroimine ring fragment of the spirolides. Organic Letters. 12: 5226-9. PMID 21028788 DOI: 10.1021/Ol102525W  1
2010 Choi PJ, Sperry J, Brimble MA. Heteroatom-directed reverse Wacker oxidations. Synthesis of the reported structure of (-)-herbaric acid. The Journal of Organic Chemistry. 75: 7388-92. PMID 20873747 DOI: 10.1021/Jo1016585  1
2010 Sperry J, Wilson ZE, Rathwell DC, Brimble MA. Isolation, biological activity and synthesis of benzannulated spiroketal natural products. Natural Product Reports. 27: 1117-37. PMID 20648380 DOI: 10.1039/B911514P  1
2010 Harris PW, Brimble MA. Toward the total chemical synthesis of the cancer protein NY-ESO-1. Biopolymers. 94: 542-50. PMID 20593475 DOI: 10.1002/Bip.21351  1
2010 Guéret SM, Brimble MA. Spiroimine shellfish poisoning (SSP) and the spirolide family of shellfish toxins: isolation, structure, biological activity and synthesis. Natural Product Reports. 27: 1350-66. PMID 20585694 DOI: 10.1039/C005400N  1
2010 Chen JL, Brimble MA. Synthesis of the bis-spiroacetal C25-C40 moiety of the antimitotic agent spirastrellolide B using a bis-dithiane deprotection/spiroacetalisation sequence. Chemical Communications (Cambridge, England). 46: 3967-9. PMID 20445924 DOI: 10.1039/C0Cc00056F  1
2010 Wilson ZE, Brimble MA. A flexible asymmetric synthesis of the tetracyclic core of berkelic acid using a Horner-Wadsworth-Emmons/oxa-Michael cascade. Organic & Biomolecular Chemistry. 8: 1284-6. PMID 20204195 DOI: 10.1039/B927219B  1
2010 Sperry J, Harris EB, Brimble MA. Total synthesis and absolute configuration of (-)-berkeleyamide A. Organic Letters. 12: 420-3. PMID 20030315 DOI: 10.1021/Ol902525K  1
2010 Sperry J, Liu YC, Brimble MA. Synthesis of natural products containing spiroketals via intramolecular hydrogen abstraction. Organic & Biomolecular Chemistry. 8: 29-38. PMID 20024126 DOI: 10.1039/B916041H  1
2010 O'Connor PD, Marino MG, Guéret SM, Brimble MA. Synthesis and reactivity of beta-methoxymethyl enecarbamates. The Journal of Organic Chemistry. 74: 8893-6. PMID 19835396 DOI: 10.1021/Jo901992Z  0.01
2010 Rathwell DC, Yang SH, Tsang KY, Brimble MA. An efficient formal synthesis of the human telomerase inhibitor (+/-)-gamma-rubromycin. Angewandte Chemie (International Ed. in English). 48: 7996-8000. PMID 19644991 DOI: 10.1002/Anie.200903316  0.01
2010 Conole D, Brimble M, Rennison D, Tingle M, Eason C. Toxicodynamics of Methemoglobin (MtHb) Inducers Proceedings of the Vertebrate Pest Conference. 24. DOI: 10.5070/v424110454  0.01
2010 McKay VA, Thompson SJ, Tran PM, Goodall KJ, Brimble MA, Barker D. Stereoselective synthesis of 4-substituted 4-hydroxypiperidines via epoxidation-ring opening of 4-methylenepiperidines Synlett. 2631-2635. DOI: 10.1055/S-0030-1258778  1
2010 Wadsworth AD, Sperry J, Brimble MA. Synthesis of the pyranonaphthoquinones dehydroherbarin, (+)-astropaquinone B and (+)-astropaquinone C en route to ascomycones A and B Synthesis. 2604-2608. DOI: 10.1055/S-0029-1218832  1
2010 Lee DJ, Harris PWR, Kowalczyk R, Dunbar PR, Brimble MA. Microwave-assisted synthesis of fluorescein-labelled GalNAcα1-O-Ser/ Thr (Tn) glycopeptides as immunological probes Synthesis. 763-769. DOI: 10.1055/S-0029-1218635  1
2010 Atkinson DJ, Sperry J, Brimble MA. Improved synthesis of the benzyne precursor 2-(trimethylsilyl)phenyl trifluoromethanesulfonate Synthesis. 911-913. DOI: 10.1055/S-0029-1218631  1
2010 Peltier R, Brimble MA, Wojnar JM, Williams DE, Evans CW, Devries AL. Synthesis and antifreeze activity of fish antifreeze glycoproteins and their analogues Chemical Science. 1: 538-551. DOI: 10.1039/C0Sc00194E  1
2010 Peltier R, Evans CW, Devries AL, Brimble MA, Dingley AJ, Williams DE. Growth habit modification of ice crystals using antifreeze glycoprotein (AFGP) analogues Crystal Growth and Design. 10: 5066-5077. DOI: 10.1021/Cg1005083  1
2010 Nikac M, Brimble MA, Crumbie RL, Bailey TD. Metal binding studies using spiroacetal thiacrown ethers Tetrahedron Letters. 51: 1072-1074. DOI: 10.1016/J.Tetlet.2009.12.110  1
2010 Chan Y, Balle J, Kevin Sparrow J, Boyd PDW, Brimble MA, Barker D. A double Mannich approach to the synthesis of substituted piperidones - Application to the synthesis of substituted E-ring analogues of methyllycaconitine Tetrahedron. 66: 7179-7191. DOI: 10.1016/J.Tet.2010.06.084  1
2010 Heapy AM, Brimble MA. Synthesis of the FG ring fragment of pectenotoxins 1-9 Tetrahedron. 66: 5424-5431. DOI: 10.1016/J.Tet.2010.05.027  1
2010 Rathwell K, Sperry J, Brimble MA. Synthesis of triazole analogues of the nanaomycin antibiotics using 'click chemistry' Tetrahedron. 66: 4002-4009. DOI: 10.1016/J.Tet.2010.04.048  1
2010 Miller N, Williams GM, Brimble MA. Synthesis of neoglycopeptides via click chemistry International Journal of Peptide Research and Therapeutics. 16: 125-132. DOI: 10.1007/S10989-010-9201-4  1
2009 Ravindran S, Hopkins B, Bova S, Rennison D, Brimble M, Tingle M. In vitro metabolism of norbormide in rat, mouse and guinea pig liver preparations. Environmental Toxicology and Pharmacology. 27: 144-8. PMID 21783932 DOI: 10.1016/J.Etap.2008.09.007  1
2009 Lee DJ, Mandal K, Harris PW, Brimble MA, Kent SB. A one-pot approach to neoglycopeptides using orthogonal native chemical ligation and click chemistry. Organic Letters. 11: 5270-3. PMID 19842689 DOI: 10.1021/Ol902131N  1
2009 Sperry J, Lorenzo-Castrillejo I, Brimble MA, Machín F. Pyranonaphthoquinone derivatives of eleutherin, ventiloquinone L, thysanone and nanaomycin A possessing a diverse topoisomerase II inhibition and cytotoxicity spectrum. Bioorganic & Medicinal Chemistry. 17: 7131-7. PMID 19783445 DOI: 10.1016/J.Bmc.2009.08.064  0.01
2009 Sperry J, Sejberg JJP, Stiemke FM, Brimble MA. Biomimetic studies towards the cardinalins: Synthesis of (+)-ventiloquinone L and an unusual dimerisation Organic and Biomolecular Chemistry. 7: 2599-2603. PMID 19503935 DOI: 10.1039/B905077A  1
2009 Miller N, Williams GM, Brimble MA. Synthesis of fish antifreeze neoglycopeptides using microwave-assisted "click chemistry". Organic Letters. 11: 2409-12. PMID 19473046 DOI: 10.1021/Ol9005536  0.01
2009 Kowalczyk R, Brimble MA, Dunbar R. Synthesis of mannosylated glycopeptides as components for synthetic vaccines. Advances in Experimental Medicine and Biology. 611: 351-2. PMID 19400222 DOI: 10.1007/978-0-387-73657-0_155  1
2009 Wilson ZE, Brimble MA. Molecules derived from the extremes of life. Natural Product Reports. 26: 44-71. PMID 19374122 DOI: 10.1039/B800164M  1
2009 Choi KW, Brimble MA. Synthesis of spiroacetal-nucleosides as privileged natural product-like scaffolds. Organic & Biomolecular Chemistry. 7: 1424-36. PMID 19300829 DOI: 10.1039/B818314G  1
2009 Guéret SM, O'Connor PD, Brimble MA. Synthesis of enantiopure bicyclic alpha,alpha-disubstituted spirolactams via asymmetric Birch reductive alkylation. Organic Letters. 11: 963-6. PMID 19199764 DOI: 10.1021/Ol8029017  0.01
2009 Bickerdike MJ, Thomas GB, Batchelor DC, Sirimanne ES, Leong W, Lin H, Sieg F, Wen J, Brimble MA, Harris PW, Gluckman PD. NNZ-2566: A Gly-Pro-Glu analogue with neuroprotective efficacy in a rat model of acute focal stroke Journal of the Neurological Sciences. 278: 85-90. PMID 19157421 DOI: 10.1016/J.Jns.2008.12.003  1
2009 Carley S, Brimble MA. A novel approach to the CDE ring system of pectenotoxin-4 triggered by VO(acac)2-induced epoxy-acetalization Organic Letters. 11: 563-566. PMID 19117488 DOI: 10.1021/Ol8025457  1
2009 Kueh J, O'Connor P, Huegen H, Brimble M. Synthetic Studies Towards the Anti-inflammatory Agent, Oleocanthal using a Johnson-Claisen (Orthoester) Rearrangement Strategy Arkivoc. 2009: 58-71. DOI: 10.3998/Ark.5550190.0010.706  1
2009 Haym I, Brimble MA. A Novel Approach to MonobenzannulatedSpiroketals Using Styrenes in the Kulinkovich Reaction Synlett. 2009: 2315-2319. DOI: 10.1055/S-0029-1217708  1
2009 Sperry J, Tsz YY, Brimble MA. Enantioselective synthesis of the 3C-protease inhibitor (-)-thysanone by a Staunton-Weinreb annulation strategy Synthesis. 2561-2569. DOI: 10.1055/S-0029-1217390  1
2009 Harris PWR, Brimble MA. Synthesis of an arginine tagged [Cys155-Arg180] fragment of NY-ESO-1: elimination of an undesired by-product using 'In house' resins Synthesis. 3460-3466. DOI: 10.1055/S-0029-1216952  1
2009 Kowalczyk R, Harris PWR, Dunbar RP, Brimble MA. Stability of 5(6)-carboxyfluorescein in microwave-assisted synthesis of fluorescein-labelled O-dimannosylated peptides Synthesis. 2210-2222. DOI: 10.1055/S-0029-1216820  1
2009 Hung KY, Harris PWR, Brimble MA. Use of 'click chemistry' for the synthesis of tetrazole-containing analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid Synlett. 1233-1236. DOI: 10.1055/S-0028-1088128  1
2009 Liu YC, Sperry J, Rathwell DCK, Brimble MA. A facile cross-metathesis-radical-cyclisation approach to monobenzannulated spiroketals Synlett. 0793-0797. DOI: 10.1055/S-0028-1087942  1
2009 Brimble M, St Clair Black D, Ciufolini MA, Fukuyama T, Fürstner A, Grigg R, Hiemstra H, MacMillan DWC, Shibasaki M, Tietze L, Wipf P. Editorial Advisory Board Members Progress in Heterocyclic Chemistry 2008-2009 Progress in Heterocyclic Chemistry. 21: xii. DOI: 10.1016/S0959-6380(09)70027-3  1
2009 Choi PJ, Rathwell DCK, Brimble MA. Synthesis of 6,6-bisbenzannulated spiroketals related to the rubromycins using a double intramolecular hetero-Michael addition (DIHMA) Tetrahedron Letters. 50: 3245-3248. DOI: 10.1016/J.Tetlet.2009.02.030  1
2009 Tong S(, Brimble MA, Barker D. Influence of α-methyl substitution of proline-based organocatalysts on the asymmetric α-oxidation of aldehydes Tetrahedron. 65: 4801-4807. DOI: 10.1016/J.Tet.2009.04.060  1
2009 O'Connor PD, Kim UB, Brimble MA. Synthesis of (±) Wine Lactone and Its Analogues by a Diels–Alder Approach (Eur. J. Org. Chem. 26/2009) European Journal of Organic Chemistry. 2009: 4371-4371. DOI: 10.1002/Ejoc.200990072  1
2009 O'Connor PD, Kim UB, Brimble MA. Synthesis of (±) Wine Lactone and Its Analogues by a Diels–Alder Approach European Journal of Organic Chemistry. 2009: 4405-4411. DOI: 10.1002/Ejoc.200900486  1
2009 Guthmann H, Conole D, Wright E, Körber K, Barker D, Brimble MA. Synthesis of AE and BE Ring Analogues of the Alkaloid Methyllycaconitine European Journal of Organic Chemistry. 2009: 1944-1960. DOI: 10.1002/Ejoc.200900030  1
2008 Tong ST, Barker D, Choi KW, Boyd PD, Brimble MA. (±)-Cyclo-hexane-1,2-diyl bis-(4-nitro-benzoate). Acta Crystallographica. Section E, Structure Reports Online. 64: o2174. PMID 21581034 DOI: 10.1107/S1600536808033874  1
2008 Crimmins D, Choi KW, Boyd PD, Brimble MA. (±)-2'-Phenyl-cyclo-hexa-nespiro-4'-(aze-pano[1,2-b]isoxazolidine). Acta Crystallographica. Section E, Structure Reports Online. 64: o1535. PMID 21203240 DOI: 10.1107/S1600536808021867  1
2008 Guéret SM, Choi KW, O'Connor PD, Boyd PD, Brimble MA. (1R,6R)-1-Methyl-8-aza-spiro-[5.6]dodecan-7-one. Acta Crystallographica. Section E, Structure Reports Online. 64: o1151. PMID 21202659 DOI: 10.1107/S1600536808015158  1
2008 Sejberg JJ, Sperry J, Choi KW, Boyd PD, Brimble MA. (1R,1'R,3S,3'S)-5,5',10,10'-Tetra-meth-oxy-1,1',3,3'-tetra-methyl-3,3',4,4'-tetra-hydro-1H,1'H-8,8'-bi[benzo[g]isochromene]. Acta Crystallographica. Section E, Structure Reports Online. 64: o758. PMID 21202147 DOI: 10.1107/S1600536808007599  1
2008 Choi KW, Brimble MA, Groutso T. (±)-1-{8'-(tert-Butyl-diphenyl-silyloxy-meth-yl)-1',7'-dioxaspiro-[5.5]undecan-2'-yl}uridine. Acta Crystallographica Section E-Structure Reports Online. 64. PMID 21202106 DOI: 10.1107/S1600536808006727  1
2008 Tong ST, Barker D, Choi KW, Boyd PD, Brimble MA. (±)-N-(3-Hydr-oxy-1,2-diphenyl-prop-yl)-4-methyl-benzene-sulfonamide. Acta Crystallographica. Section E, Structure Reports Online. 64: o1990. PMID 21201189 DOI: 10.1107/S1600536808028948  1
2008 Rathwell DC, Tsang KY, Choi KW, Boyd PD, Brimble MA. 3-Allyl-2-hydr-oxy-5,6,8-trimethoxy-naphthalene-1,4-dione. Acta Crystallographica. Section E, Structure Reports Online. 64: o1929. PMID 21201137 DOI: 10.1107/S1600536808028432  1
2008 Choi KW, Brimble MA. Synthesis of spiroacetal-triazoles as privileged natural product-like scaffolds using "click chemistry". Organic & Biomolecular Chemistry. 6: 3518-26. PMID 19082152 DOI: 10.1039/B808454H  1
2008 Sperry J, Gibson JS, Sejberg JJ, Brimble MA. Enantioselective synthesis of the dimeric pyranonaphthoquinone core of the cardinalins using a late-stage homocoupling strategy. Organic & Biomolecular Chemistry. 6: 4261-70. PMID 18972059 DOI: 10.1039/B813605J  1
2008 Radcliff FJ, Fraser JD, Wilson ZE, Heapy AM, Robinson JE, Bryant CJ, Flowers CL, Brimble MA. Anti-Helicobacter pylori activity of derivatives of the phthalide-containing antibacterial agents spirolaxine methyl ether, CJ-12,954, CJ-13,013, CJ-13,102, CJ-13,104, CJ-13,108 and CJ-13,015. Bioorganic & Medicinal Chemistry. 16: 6179-85. PMID 18457954 DOI: 10.1016/J.Bmc.2008.04.037  1
2008 Sperry J, Bachu P, Brimble MA. Pyranonaphthoquinones - Isolation, biological activity and synthesis Natural Product Reports. 25: 376-400. PMID 18389142 DOI: 10.1039/B708811F  1
2008 Brimble MA, Kowalczyk R, Harris PW, Dunbar PR, Muir VJ. Synthesis of fluorescein-labelled O-mannosylated peptides as components for synthetic vaccines: comparison of two synthetic strategies. Organic & Biomolecular Chemistry. 6: 112-21. PMID 18075655 DOI: 10.1039/B712926B  1
2008 Goodall K, Brimble M, Barker D. 1H and 13C NMR spectra of C-6 and C-9 substituted 3-azabicyclco[3.3.1]nonanes. Magnetic Resonance in Chemistry. 46: 75-79. PMID 18041010 DOI: 10.1002/Mrc.2100  1
2008 Sperry J, Brimble MA. An efficient enantioselective synthesis of the 3C protease inhibitor (-)-thysanone Synlett. 1910-1912. DOI: 10.1055/S-2008-1078590  1
2008 O’Connor PD, Körber K, Brimble MA. Novel Use of N-Carboalkoxy α,β-Unsaturated Iminium Ions as Dienophiles in Diels-Alder Reactions Synlett. 2008: 1036-1038. DOI: 10.1055/S-2008-1072658  1
2008 Lorimer AV, O'Connor PD, Brimble MA. Buchwald-Hartwig Mono-N-arylation with 2,6-dihaloisonicotinic acid derivatives: A convenient desymmetrization method Synthesis. 2764-2770. DOI: 10.1055/S-2008-1067208  1
2008 Brimble MA, Gibson JS, Sejberg JJP, Sperry J. A facile enantioselective synthesis of the dimeric pyranonaphthoquinone core of the cardinalins Synlett. 867-870. DOI: 10.1055/S-2008-1042896  1
2008 Chan Y, Guthmann H, Brimble MA, Barker D. Diastereoselective Synthesisof Substituted 4-Piperidones and 4-Piperidols Using a Double MannichReaction Synlett. 2008: 2601-2604. DOI: 10.1055/S-0028-1083522  1
2008 Crimmins D, Dimitrov I, O’Connor PD, Caprio V, Brimble MA. A Facile Synthesis of a Spironitrone and a Study of Its Cycloaddition and Nucleophilic Addition Reactions Synthesis. 2008: 3319-3325. DOI: 10.1055/S-0028-1083151  1
2008 Andrey O, Sperry J, Larsen US, Brimble MA. An approach to an enantioselective synthesis of crisamicin A via a novel double Hauser-Kraus annulation strategy Tetrahedron. 64: 3912-3927. DOI: 10.1016/J.Tet.2008.02.065  1
2008 Bachu P, Sperry J, Brimble MA. Synthesis of a C8 oxygenated pyranonaphthoquinone: a useful precursor to dimeric pyranonaphthoquinones Tetrahedron. 64: 3343-3350. DOI: 10.1016/J.Tet.2008.01.135  1
2008 Bachu P, Sperry J, Brimble MA. Chemoenzymatic synthesis of deoxy analogues of the DNA topoisomerase II inhibitor eleutherin and the 3C-protease inhibitor thysanone Tetrahedron. 64: 4827-4834. DOI: 10.1016/J.Tet.2008.01.112  1
2008 Harris PWR, Williams GM, Shepherd P, Brimble MA. The synthesis of phosphopeptides using microwave-assisted solid phase peptide synthesis International Journal of Peptide Research and Therapeutics. 14: 387-392. DOI: 10.1007/S10989-008-9149-9  1
2008 Tong ST, Harris PWR, Barker D, Brimble MA. Use of (S)-5-(2-methylpyrrolidin-2-yl)-1H-tetrazole as a novel and enantioselective organocatalyst for the aldol reaction European Journal of Organic Chemistry. 164-170. DOI: 10.1002/Ejoc.200700834  1
2007 Robinson JE, Brimble MA. Synthesis of the anti-Helicobacter pylori agent (+)-spirolaxine methyl ether and the unnatural (2"S)-diastereomer. Organic & Biomolecular Chemistry. 5: 2572-82. PMID 18019531 DOI: 10.1039/B708265G  1
2007 Guan J, Mathai S, Harris P, Wen JY, Zhang R, Brimble M, Gluckman P. Peripheral administration of a novel diketopiperazine, NNZ 2591, prevents brain injury and improves somatosensory-motor function following hypoxia-ischemia in adult rats Neuropharmacology. 53: 749-762. PMID 17904590 DOI: 10.1016/J.Neuropharm.2007.08.010  1
2007 Lee DJ, Kowalczyk R, Muir VJ, Rendle PM, Brimble MA. A comparative study of different glycosylation methods for the synthesis of D-mannopyranosides of Nalpha-fluorenylmethoxycarbonyl-trans-4-hydroxy-L-proline allyl ester. Carbohydrate Research. 342: 2628-34. PMID 17854783 DOI: 10.1016/J.Carres.2007.08.015  1
2007 Brimble MA, Bryant CJ. Synthesis and assignment of the absolute configuration of the anti-Helicobacter pylori agents CJ-12,954 and CJ-13,014 Organic and Biomolecular Chemistry. 5: 2858-2866. PMID 17700855 DOI: 10.1039/B709932K  1
2007 O'Connor PD, Brimble MA. Synthesis of macrocyclic shellfish toxins containing spiroimine moieties. Natural Product Reports. 24: 869-85. PMID 17653363 DOI: 10.1039/B700307M  0.01
2007 Goodall KJ, Brimble MA, Barker D. 1H and 13C NMR spectra of methylmaleimido- and methylsuccinimidoanthranilate esters of 1-hydroxymethyl-6-methoxy-3-azabicyclo[3.3.1]nonanes. Magnetic Resonance in Chemistry. 45: 695-699. PMID 17568454 DOI: 10.1002/Mrc.2027  1
2007 Zulian A, Petronilli V, Bova S, Dabbeni-Sala F, Cargnelli G, Cavalli M, Rennison D, Stäb J, Laita O, Lee DJ, Brimble MA, Hopkins B, Bernardi P, Ricchelli F. Assessing the molecular basis for rat-selective induction of the mitochondrial permeability transition by norbormide. Biochimica Et Biophysica Acta. 1767: 980-8. PMID 17509521 DOI: 10.1016/J.Bbabio.2007.04.002  1
2007 Rennison D, Bova S, Cavalli M, Ricchelli F, Zulian A, Hopkins B, Brimble MA. Synthesis and activity studies of analogues of the rat selective toxicant norbormide Bioorganic and Medicinal Chemistry. 15: 2963-2974. PMID 17321141 DOI: 10.1016/J.Bmc.2007.02.012  1
2007 Halim R, Brimble MA. Synthetic studies towards the pectenotoxins: a review. Organic & Biomolecular Chemistry. 4: 4048-58. PMID 17312955 DOI: 10.1039/B611531B  0.01
2007 Brimble MA, Halim R. Synthetic studies toward shellfish toxins containing spiroacetal units Pure and Applied Chemistry. 79: 153-162. DOI: 10.1351/Pac200779020153  1
2007 Brimble M. Science of Synthesis, Volume 28: Compounds with Two Carbon-Heteroatom Bonds: Quinones and Heteroatom Analogues Synthesis. 2007: 2924-2924. DOI: 10.1055/S-2007-990452  1
2007 Brimble MA, Bachu P, Sperry J. Enantioselective synthesis of an analogue of nanaomycin A Synthesis. 2887-2893. DOI: 10.1055/S-2007-983848  1
2007 Gibson JS, Andrey O, Brimble MA. A short enantioselective synthesis of the topoisomerase II inhibitor (+)-eleutherin Synthesis. 2611-2613. DOI: 10.1055/S-2007-983841  1
2007 Harris PWR, Brimble MA, Dunbar R, Kent SBH. Synthesis of a C-terminal thioester derivative of the lipopeptide Pam 2CSKKKKG using Fmoc SPPS Synlett. 713-716. DOI: 10.1055/S-2007-970759  1
2007 Brimble MA, Liu Y(, Trzoss M. A Facile Synthesis of Aryl Spirodioxines Based on a 3H,3′H-2,2′-Spiro-bi(benzo[b][1,4]dioxine) Skeleton Synthesis. 2007: 1392-1402. DOI: 10.1055/S-2007-966016  1
2007 Rathwell K, Brimble MA. Use of Stabilized Phthalide Anion Annulation Reactions in Synthesis: An Update Synthesis. 2007: 643-662. DOI: 10.1055/S-2007-965915  1
2007 Brimble MA, Burgess CV. A Facile Synthesis of 1,1′-Spirobi(3H,3′H)isobenzofurans Synthesis. 2007: 754-760. DOI: 10.1055/S-2007-965911  0.01
2007 Bachu P, Gibson JS, Sperry J, Brimble MA. The influence of microwave irradiation on lipase-catalyzed kinetic resolution of racemic secondary alcohols Tetrahedron Asymmetry. 18: 1618-1624. DOI: 10.1016/J.Tetasy.2007.06.035  1
2007 Wilson ZE, Heapy AM, Brimble MA. Synthesis of indole analogues of the anti-Helicobacter pylori compounds CJ-13,015, CJ-13,102, CJ-13,104 and CJ-13,108 Tetrahedron. 63: 5379-5385. DOI: 10.1016/J.Tet.2007.04.067  1
2007 Nikac M, Brimble MA, Crumbie RL. Synthesis of thiacrown and azacrown ethers based on a spiroacetal framework Tetrahedron. 63: 5220-5226. DOI: 10.1016/J.Tet.2007.03.174  1
2007 Tsang KY, Brimble MA. Synthesis of aromatic spiroacetals related to γ-rubromycin based on a 3H-spiro[1-benzofuran-2,2′-chromane] skeleton Tetrahedron. 63: 6015-6034. DOI: 10.1016/J.Tet.2007.02.033  1
2007 Brimble MA, Houghton SI, Woodgate PD. Synthesis of a regioisomeric analogue of the 3C-protease inhibitor thysanone via a Hauser annulation strategy Tetrahedron. 63: 880-887. DOI: 10.1016/J.Tet.2006.11.046  1
2007 Hebditch KR, Nicolau L, Brimble MA. Synthesis of isotopically labelled thiol volatiles and cysteine conjugates for quantification of Sauvignon Blanc wine Journal of Labelled Compounds and Radiopharmaceuticals. 50: 237-243. DOI: 10.1002/Jlcr.1262  0.01
2006 Brimble MA, Levi MS. A review of agents patented for their neuroprotective properties. Recent Patents On Cns Drug Discovery. 1: 139-46. PMID 18221199 DOI: 10.2174/157488906777452758  1
2006 Brimble MA, Bryant CJ. Synthesis of the spiroacetal-containing anti-Helicobacter pylori agents CJ-12,954 and CJ-13,014 Chemical Communications. 4506-4508. PMID 17283800 DOI: 10.1039/B612757F  1
2006 Goodall KJ, Brimble MA, Barker D. 1H and 13C NMR data for C-6 substituted 3-azabicyclo[3.3.1]nonane-1-carboxylates. Magnetic Resonance in Chemistry. 44: 980-983. PMID 16868917 DOI: 10.1002/Mrc.1878  1
2006 Harris PWR, Brimble MA. Synthesis of macrocyclic analogues of the neuroprotective agent glycyl-l-prolyl-l-glutamic acid (GPE) Organic and Biomolecular Chemistry. 4: 2696-2709. PMID 16826294 DOI: 10.1039/B605293B  1
2006 Meilert K, Brimble MA. Synthesis of the bis-spiroacetal moiety of the shellfish toxins spirolides B and D using an iterative oxidative radical cyclization strategy. Organic & Biomolecular Chemistry. 4: 2184-92. PMID 16729128 DOI: 10.1039/B604334H  0.01
2006 Halim R, Brimble MA, Merten J. Synthesis of the ABC tricyclic fragment of the pectenotoxins via stereocontrolled cyclization of a gamma-hydroxyepoxide appended to the AB spiroacetal unit. Organic & Biomolecular Chemistry. 4: 1387-99. PMID 16557329 DOI: 10.1039/B600951D  0.01
2006 Meilert K, Brimble MA. Synthesis of the bis-spiroacetal moiety of spirolides B and D. Organic Letters. 7: 3497-500. PMID 16048326 DOI: 10.1021/Ol051260U  0.01
2006 Halim R, Brimble MA, Merten J. Synthesis of the ABC fragment of the pectenotoxins. Organic Letters. 7: 2659-62. PMID 15957915 DOI: 10.1021/Ol0507975  0.01
2006 Clark GR, Robinson JE, Brimble MA. (2″S,5″R,7″S)-2-[2′-Methyl-1″, 6″-dioxaspiro[4.5]dec-7″-ylethylsulfonyl]-1,3-benzothiazole Acta Crystallographica Section E: Structure Reports Online. 62: o1187-o1188. DOI: 10.1107/S1600536806006544  1
2006 Clark GR, Tsang KY, Brimble MA. 8′-Methoxy-3H-spiro[1-naphthofuran2,2′-chroman] Acta Crystallographica Section E: Structure Reports Online. 62: o1075-o1076. DOI: 10.1107/S1600536806005125  1
2006 Brimble MA, Robinson JE, Merten J, Beuzenberg V, Dragunow M, Holland P, Mountfort D. A novel bromine-induced ring expansion of the spiroimine moiety of the shellfish toxin gymnodimine Synlett. 1610-1612. DOI: 10.1055/S-2006-941605  1
2006 Brimble MA, Flowers CL, Trzoss M, Tsang KY. A facile synthesis of fused aromatic spiroacetals based on the 3,4,3′,4′-tetrahydro-2,2′-spirobis(2H-1-benzopyran) skeleton Tetrahedron. 62: 5883-5896. DOI: 10.1016/J.Tet.2006.04.026  1
2006 Brimble MA, Laita O, Robinson JE. Addition of 2-tert-butyldimethylsilyloxythiophene to activated quinones: an approach to thia analogues of kalafungin Tetrahedron. 62: 3021-3027. DOI: 10.1016/J.Tet.2006.01.040  1
2006 Harris PWR, Brimble MA. Synthesis of isotopically labelled glycyl-L-prolyl-L-glutamic acid (Glypromate®) and derivatives Journal of Labelled Compounds and Radiopharmaceuticals. 49: 571-581. DOI: 10.1002/Jlcr.1075  1
2006 Lehmann A, Brocke C, Barker D, Brimble MA. Synthesis of N-(3-phenylpropyl)-substituted tricyclic ABE ring analogues of the alkaloid methyllycaconitine European Journal of Organic Chemistry. 2006: 3205-3215. DOI: 10.1002/Ejoc.200600326  1
2006 Rodríguez García E, Brimble MA, Vogel P. Synthesis of New Aza-C-disaccharides Linking 4-Deoxy-4-amino-β-L-erythro-furanose to C-2 ofD-Glucose andD-Allose European Journal of Organic Chemistry. 2006: 3845-3855. DOI: 10.1002/Ejoc.200600199  0.01
2005 Dragunow M, Trzoss M, Brimble MA, Cameron R, Beuzenberg V, Holland P, Mountfort D. Investigations into the cellular actions of the shellfish toxin gymnodimine and analogues. Environmental Toxicology and Pharmacology. 20: 305-12. PMID 21783605 DOI: 10.1016/J.Etap.2005.02.008  1
2005 Barker D, Lin DH, Carland JE, Chu CP, Chebib M, Brimble MA, Savage GP, McLeod MD. Methyllycaconitine analogues have mixed antagonist effects at nicotinic acetylcholine receptors. Bioorganic & Medicinal Chemistry. 13: 4565-75. PMID 15922601 DOI: 10.1016/J.Bmc.2005.04.054  1
2005 Robinson JE, Brimble MA. The first enantioselective total synthesis of the anti-Helicobacter pylori agent (+)-spirolaxine methyl ether. Chemical Communications (Cambridge, England). 1560-2. PMID 15770259 DOI: 10.1039/B418106A  1
2005 Lai MYH, Brimble MA, Callis DJ, Harris PWR, Levi MS, Sieg F. Synthesis and pharmacological evaluation of glycine-modified analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE) Bioorganic and Medicinal Chemistry. 13: 533-548. PMID 15598574 DOI: 10.1016/J.Bmc.2004.10.004  1
2005 Brimble MA, Trotter NS, Harris PWR, Sieg F. Synthesis and pharmacological evaluation of side chain modified glutamic acid analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE) Bioorganic and Medicinal Chemistry. 13: 519-532. PMID 15598573 DOI: 10.1016/J.Bmc.2004.10.006  1
2005 Trotter NS, Brimble MA, Harris PWR, Callis DJ, Sieg F. Synthesis and neuroprotective activity of analogues of glycyl-L-prolyl-L- glutamic acid (GPE) modified at the α-carboxylic acid Bioorganic and Medicinal Chemistry. 13: 501-517. PMID 15598572 DOI: 10.1016/J.Bmc.2004.10.005  1
2005 Brimble M, Steel P. A Tribute to Prof. Jim Coxon Arkivoc. 2006. DOI: 10.3998/Ark.5550190.0007.301  1
2005 Brimble M, Savage P. A Tribute to Don Cameron Arkivoc. 2001. DOI: 10.3998/Ark.5550190.0002.701  1
2005 Clark GR, Tsang KY, Brimble MA. 5,8′-Dimethoxy-3H-1-benzofuran-2-spiro-2′-chroman Acta Crystallographica Section E: Structure Reports Online. 61: o2748-o2749. DOI: 10.1107/S1600536805023731  1
2005 Clark GR, Flowers CL, Brimble MA. 6,8′-Dimethoxy-2,2′-spirobichroman Acta Crystallographica Section E: Structure Reports Online. 61: o910-o911. DOI: 10.1107/S1600536805006938  1
2005 Meilert KT, Clark GR, Groutso T, Brimble MA. (1S,2S)-1-{2-[(4-Methoxybenzyl)oxy]ethyl}-2-methyl-3-butenyl (1S,4R)-4,7,7-trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylate Acta Crystallographica Section E: Structure Reports Online. 61: o6-o7. DOI: 10.1107/S1600536804030946  1
2005 Goodall KJ, Barker D, Brimble MA. A Review of Advances in the Synthesis of Analogues of the Delphinium Alkaloid Methyllycaconitine Synlett. 2005: 1809-1827. DOI: 10.1055/S-2005-871575  1
2005 Guan J, Mathai S, Sieg F, Gorba T, Brimble M, Gluckman P. Neuroprotective effects of diketopiperazines, potential clinical application of small cyclic form of neuropeptide following ischemic brain injury Journal of Cerebral Blood Flow and Metabolism. 25. DOI: 10.1038/Sj.Jcbfm.9591524.0054  1
2005 Brimble MA, Flowers CL, Hutchinson JK, Robinson JE, Sidford M. Synthesis of the phthalide-containing anti-Helicobacter pylori agents CJ-13,015, CJ-13,102, CJ-13,103, CJ-13,104 and CJ-13,108 Tetrahedron. 61: 10036-10047. DOI: 10.1016/J.Tet.2005.08.027  1
2005 Harris PWR, Brimble MA, Muir VJ, Lai MYH, Trotter NS, Callis DJ. Synthesis of proline-modified analogues of the neuroprotective agent glycyl-L-prolyl-glutamic acid (GPE) Tetrahedron. 61: 10018-10035. DOI: 10.1016/J.Tet.2005.08.026  1
2005 Buckley BR, Page PCB, Heaney H, Sampler EP, Carley S, Brocke C, Brimble MA. Use of bis-(aminol) ethers derived from N-(S)-(-)-α-methylbenzylamine in reactions with resorcinarenes and double Mannich reactions Tetrahedron. 61: 5876-5888. DOI: 10.1016/J.Tet.2005.03.130  1
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