Margaret A. Brimble - Publications

Affiliations: 
Chemistry The University of Auckland, Auckland, Auckland, New Zealand 

265 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Grant PS, Kahlcke N, Govindpani K, Hunter M, MacDonald C, Brimble MA, Glass M, Furkert DP. Divalent cannabinoid-1 receptor ligands: A linker attachment point survey of SR141716A for development of high-affinity CB1R molecular probes. Bioorganic & Medicinal Chemistry Letters. 126644. PMID 31564385 DOI: 10.1016/j.bmcl.2019.126644  1
2019 Brimble MA, Xu B, Hermant Y, Yang SH, Harris P. A versatile Boc solid phase synthesis of daptomycin and analogues using site specific, on-resin ozonolysis to install the kynurenine residue. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31429133 DOI: 10.1002/chem.201903725  0.56
2019 Jeong JY, Sperry J, Brimble MA. Synthesis of the Tetracyclic Cores of the Integrastatins, Epicoccolide A and Epicocconigrone A. The Journal of Organic Chemistry. PMID 31416308 DOI: 10.1021/acs.joc.9b01796  0.52
2019 Kasim JK, Kavianinia I, Harris PWR, Brimble MA. Three Decades of Amyloid Beta Synthesis: Challenges and Advances. Frontiers in Chemistry. 7: 472. PMID 31334219 DOI: 10.3389/fchem.2019.00472  0.56
2019 Musa H, Hendrikse E, Brimble MA, Garelja M, Watkins HA, Harris PWR, Hay DL. Pharmacological characterization and investigation of N-terminal loop amino acids of adrenomedullin 2 that are important for receptor activation. Biochemistry. PMID 31328503 DOI: 10.1021/acs.biochem.9b00571  0.56
2019 Daniels BJ, Li FF, Furkert DP, Brimble MA. Naturally Occurring Lumazines. Journal of Natural Products. PMID 31317731 DOI: 10.1021/acs.jnatprod.9b00351  1
2019 Davison EK, Cameron AJ, Harris PWR, Brimble MA. Synthesis of endolides A and B: naturally occurring -methylated cyclic tetrapeptides. Medchemcomm. 10: 693-698. PMID 31191859 DOI: 10.1039/c9md00050j  0.56
2019 Stubbing LA, Kavianinia I, Abbattista MR, Harris PWR, Smaill JB, Patterson AV, Brimble MA. Synthesis and antiproliferative activity of culicinin D analogues containing simplified AHMOD-based residues. European Journal of Medicinal Chemistry. 177: 235-246. PMID 31152989 DOI: 10.1016/j.ejmech.2019.05.052  0.68
2019 Ng J, Kaur H, Collier T, Chang K, Brooks AES, Allison JR, Brimble MA, Hickey A, Birch NP. Site-specific glycations of Aβ1-42 affect fibril formation and are neurotoxic. The Journal of Biological Chemistry. PMID 30996005 DOI: 10.1074/jbc.RA118.006846  0.48
2019 Cameron AJ, Squire CJ, Gérenton A, Stubbing LA, Harris PWR, Brimble MA. Investigations of the key macrolactamisation step in the synthesis of cyclic tetrapeptide pseudoxylallemycin A. Organic & Biomolecular Chemistry. PMID 30941386 DOI: 10.1039/c9ob00227h  0.68
2019 Freeman JL, Brimble MA, Furkert DP. Convenient access to 5-membered cyclic iminium ions: evidence for a stepwise [4 + 2] cycloaddition mechanism. Organic & Biomolecular Chemistry. PMID 30768089 DOI: 10.1039/c9ob00262f  1
2019 Khalil ZG, Hill TA, De Leon Rodriguez LM, Lohman RJ, Hoang HN, Reiling N, Hillemann D, Brimble MA, Fairlie D, Blumenthal A, Capon RJ. Structure-activity relationships of wollamide cyclic hexapeptides with activity against drug-resistant and intracellular . Antimicrobial Agents and Chemotherapy. PMID 30602509 DOI: 10.1128/AAC.01773-18  0.68
2018 Kasim JK, Kavianinia I, Ng J, Harris PWR, Birch NP, Brimble MA. Efficient synthesis and characterisation of the amyloid beta peptide, Aβ, using a double linker system. Organic & Biomolecular Chemistry. PMID 30500032 DOI: 10.1039/c8ob02929f  0.56
2018 Xu B, Aitken EJ, Baker BP, Turner CA, Harvey JE, Stott MB, Power JF, Harris PWR, Keyzers RA, Brimble MA. Genome mining, isolation, chemical synthesis and biological evaluation of a novel lanthipeptide, tikitericin, from the extremophilic microorganism strain T81. Chemical Science. 9: 7311-7317. PMID 30294420 DOI: 10.1039/c8sc02170h  0.56
2018 Ding XB, Brimble MA, Furkert DP. Reactivity of 2-Nitropyrrole Systems: Development of Improved Synthetic Approaches to Nitropyrrole Natural Products. The Journal of Organic Chemistry. PMID 30270625 DOI: 10.1021/acs.joc.8b01692  1
2018 Pilkington L, Yang X, Liu MW, Hemar Y, Brimble M, Reynisson J. A chemometric analysis of compounds from native New Zealand medicinal flora. Chemistry, An Asian Journal. PMID 30125474 DOI: 10.1002/asia.201800803  0.68
2018 Grant P, Brimble M, Furkert DP. Synthesis of the Bicyclic Lactone Core of Leonuketal Enabled by a Telescoped Diels-Alder Reaction Sequence. Chemistry, An Asian Journal. PMID 30058292 DOI: 10.1002/asia.201800903  1
2018 Wood JM, Furkert DP, Brimble MA. 2-Formylpyrrole natural products: origin, structural diversity, bioactivity and synthesis. Natural Product Reports. PMID 30039828 DOI: 10.1039/c8np00051d  1
2018 Simms J, Uddin R, Sakmar TP, Gingell JJ, Garelja ML, Hay DL, Brimble MA, Harris PWR, Reynolds CA, Poyner DR. Photoaffinity cross-linking and unnatural amino acid mutagenesis reveal insights into calcitonin gene-related peptide binding to the calcitonin receptor-like receptor/receptor activity-modifying protein 1 (CLR/RAMP1) complex. Biochemistry. PMID 30004692 DOI: 10.1021/acs.biochem.8b00502  0.56
2018 Zhang S, De Leon Rodriguez LM, Huang R, Leung IKH, Harris PWR, Brimble MA. Total synthesis of the proposed structure of talarolide A. Organic & Biomolecular Chemistry. PMID 29989642 DOI: 10.1039/c8ob01230j  0.68
2018 Bisset SW, Yang SH, Amso Z, Harris PWR, Patchett ML, Brimble MA, Norris GE. Using Chemical Synthesis to Probe Structure-Activity Relationships of the Glycoactive Bacteriocin Glycocin F. Acs Chemical Biology. PMID 29701461 DOI: 10.1021/acschembio.8b00055  1
2018 Amso Z, Bisset SW, Yang SH, Harris PWR, Wright TH, Navo CD, Patchett ML, Norris GE, Brimble MA. Total chemical synthesis of glycocin F and analogues: -glycosylation confers improved antimicrobial activity. Chemical Science. 9: 1686-1691. PMID 29675216 DOI: 10.1039/c7sc04383j  1
2018 Shirley HJ, Jamieson ML, Brimble MA, Bray CD. A new family of sesterterpenoids isolated around the Pacific Rim. Natural Product Reports. PMID 29547216 DOI: 10.1039/C7NP00049A  0.76
2018 Pantin M, Brimble MA, Furkert DP. Total Synthesis of (-)-Peniphenone A. The Journal of Organic Chemistry. PMID 29480005 DOI: 10.1021/acs.joc.7b03231  1
2018 Garelja ML, Walker CA, Siow A, Yang SH, Harris PWR, Brimble MA, Watkins HA, Gingell JJ, Hay DL. Receptor activity-modifying proteins have limited effects on the class B G protein-coupled receptor calcitonin receptor-like receptor stalk. Biochemistry. PMID 29388762 DOI: 10.1021/acs.biochem.7b01180  0.56
2018 Brimble MA, Zhang S, De Leon Rodriguez L, Leung I, Cook G, Harris P. Total Synthesis and Conformational Study of The Anti-tubercular Cyclic Peptide Callyaerin A Bearing a Rare Rigidifying (Z)-2,3- Diaminoacrylamide Moiety. Angewandte Chemie (International Ed. in English). PMID 29345033 DOI: 10.1002/anie.201712792  0.4
2018 Siow A, Opiyo G, Kavianinia I, Li FF, Furkert DP, Harris PWR, Brimble MA. Total Synthesis of the Highly N-Methylated Acetylene-Containing Anticancer Peptide Jahanyne. Organic Letters. PMID 29337569 DOI: 10.1021/acs.orglett.7b03925  1
2017 Mountjoy KG, Caron A, Hubbard K, Shome A, Grey AC, Sun B, Bould S, Middleditch M, Pontré B, McGregor A, Harris PWR, Kowalczyk R, Brimble MA, Botha R, Tan KML, et al. Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance. Molecular Metabolism. PMID 29226825 DOI: 10.1016/j.molmet.2017.11.008  0.56
2017 Evans GL, Furkert DP, Abermil N, Kundu P, de Lange KM, Parker EJ, Brimble MA, Baker EN, Lott JS. Datasets, processing and refinement details for Mtb-AnPRT: inhibitor structures with various space groups. Data in Brief. 15: 1019-1029. PMID 29167811 DOI: 10.1016/j.dib.2017.10.051  1
2017 Kowalczyk R, Harris PWR, Williams GM, Yang SH, Brimble MA. Peptide Lipidation - A Synthetic Strategy to Afford Peptide Based Therapeutics. Advances in Experimental Medicine and Biology. 1030: 185-227. PMID 29081055 DOI: 10.1007/978-3-319-66095-0_9  0.56
2017 Anderson RJ, Li J, Kedzierski L, Compton BJ, Hayman CM, Osmond TL, Tang CW, Farrand KJ, Koay HF, Almeida CFDSSE, Holz LR, Williams GM, Brimble MA, Wang Z, Koutsakos M, et al. Augmenting influenza-specific T cell memory generation with a NKT cell-dependent glycolipid-peptide vaccine. Acs Chemical Biology. PMID 29043774 DOI: 10.1021/acschembio.7b00845  0.36
2017 Schumacher CE, Harris PWR, Ding XB, Krause B, Wright TH, Cook GM, Furkert DP, Brimble MA. Synthesis and biological evaluation of novel teixobactin analogues. Organic & Biomolecular Chemistry. PMID 28993827 DOI: 10.1039/c7ob02169k  1
2017 Pantin M, Hubert JG, Söhnel T, Brimble MA, Furkert DP. Stereochemical Characterisation of Polyketide Stereotriads Synthesized via Hydrogen Mediated Asymmetric Syn-Crotylation. The Journal of Organic Chemistry. PMID 28960976 DOI: 10.1021/acs.joc.7b01820  1
2017 Ding XB, Furkert DP, Brimble MA. General Synthesis of the Nitropyrrolin Family of Natural Products via Regioselective CO2-Mediated Alkyne Hydration. Organic Letters. PMID 28898092 DOI: 10.1021/acs.orglett.7b02687  1
2017 De Leon-Rodriguez LM, Hemar Y, Mitra AK, Brimble MA. Understanding the metal mediated assembly and hydrogel formation of a β-hairpin peptide. Biomaterials Science. PMID 28853745 DOI: 10.1039/c7bm00512a  0.68
2017 Evans GL, Furkert DP, Abermil N, Kundu P, de Lange KM, Parker EJ, Brimble MA, Baker EN, Shaun Lott J. Anthranilate phosphoribosyltransferase: Binding determinants for 5'-phospho-alpha-d-ribosyl-1'-pyrophosphate (PRPP) and the implications for inhibitor design. Biochimica Et Biophysica Acta. PMID 28844746 DOI: 10.1016/j.bbapap.2017.08.018  1
2017 Kavianinia I, Yang SH, Kaur H, Harris PWR, Dobson RCJ, Fairbanks AJ, Brimble MA. Synthesis and incorporation of an advanced lipid peroxidation end-product building block into collagen mimetic peptides. Chemical Communications (Cambridge, England). PMID 28702630 DOI: 10.1039/c7cc05025a  0.56
2017 Lutteroth KR, Harris PWR, Wright TH, Kaur H, Sparrow K, Yang SH, Cooper GJS, Brimble MA. Incorporation of 'click' chemistry glycomimetics dramatically alters triple-helix stability in an adiponectin model peptide. Organic & Biomolecular Chemistry. PMID 28639641 DOI: 10.1039/c7ob01388d  0.56
2017 Badrinarayanan S, Squire CJ, Sperry J, Brimble MA. Bioinspired Total Synthesis and Stereochemical Revision of the Fungal Metabolite Pestalospirane B. Organic Letters. PMID 28621951 DOI: 10.1021/acs.orglett.7b01371  0.52
2017 Wood JM, Furkert DP, Brimble MA. Total Synthesis and Stereochemical Revision of the 2-Formylpyrrole Alkaloid Hemerocallisamine I. Journal of Natural Products. PMID 28590122 DOI: 10.1021/acs.jnatprod.7b00314  1
2017 Choi H, Shirley HJ, Hume PA, Brimble MA, Furkert DP. Unexpected Direct Synthesis of N-Vinyl Amides through Vinyl Azide-Enolate [3+2] Cycloaddition. Angewandte Chemie (International Ed. in English). PMID 28544052 DOI: 10.1002/anie.201702727  1
2017 Stubbing LA, Kavianinia I, Brimble MA. Synthesis of AHMOD-containing aminolipopeptides, unique bioactive peptaibiotics. Organic & Biomolecular Chemistry. PMID 28398442 DOI: 10.1039/c7ob00541e  0.68
2017 Quach R, Furkert DP, Brimble MA. Gold catalysis: synthesis of spiro, bridged, and fused ketal natural products. Organic & Biomolecular Chemistry. PMID 28287235 DOI: 10.1039/c7ob00496f  1
2016 Medini K, Harris PWR, Menorca A, Hards K, Cook GM, Brimble MA. Synthesis and activity of a diselenide bond mimetic of the antimicrobial protein caenopore-5. Chemical Science. 7: 2005-2010. PMID 29899924 DOI: 10.1039/c5sc04187b  0.56
2016 Atkinson DJ, Naysmith BJ, Furkert DP, Brimble MA. Enduracididine, a rare amino acid component of peptide antibiotics: Natural products and synthesis. Beilstein Journal of Organic Chemistry. 12: 2325-2342. PMID 28144300 DOI: 10.3762/bjoc.12.226  1
2016 Naysmith BJ, Hume PA, Sperry J, Brimble MA. Pyranonaphthoquinones - isolation, biology and synthesis: an update. Natural Product Reports. PMID 27759131 DOI: 10.1039/c6np00080k  0.56
2016 De Leon-Rodriguez LM, Hemar Y, Mo G, Mitra AK, Cornish J, Brimble MA. Multifunctional thermoresponsive designer peptide hydrogels. Acta Biomaterialia. PMID 27744067 DOI: 10.1016/j.actbio.2016.10.014  1
2016 Ding XB, Furkert DP, Brimble MA. 2-Nitropyrrole cross-coupling enables a second generation synthesis of the heronapyrrole antibiotic natural product family. Chemical Communications (Cambridge, England). PMID 27722263 DOI: 10.1039/c6cc07532k  1
2016 Kaur H, Kamalov M, Brimble MA. Chemical Synthesis of Peptides Containing Site-Specific Advanced Glycation Endproducts. Accounts of Chemical Research. PMID 27672697 DOI: 10.1021/acs.accounts.6b00366  0.48
2016 Quach R, Furkert DP, Brimble MA. Total Synthesis of the Resorcyclic Acid Lactone Spiroketal Citreoviranol. The Journal of Organic Chemistry. PMID 27505436 DOI: 10.1021/acs.joc.6b01503  1
2016 Kavianinia I, Kunalingam L, Harris PW, Cook GM, Brimble MA. Total Synthesis and Stereochemical Revision of the Anti-Tuberculosis Peptaibol Trichoderin A. Organic Letters. PMID 27467118 DOI: 10.1021/acs.orglett.6b01886  0.44
2016 Wood JM, Furkert DP, Brimble MA. Synthesis of the 2-formylpyrrole spiroketal pollenopyrroside A and structural elucidation of xylapyrroside A, shensongine A and capparisine B. Organic & Biomolecular Chemistry. PMID 27452965 DOI: 10.1039/c6ob01361a  1
2016 Ngen ST, Kaur H, Hume PA, Furkert DP, Brimble MA. Synthesis of Psychrophilin E. The Journal of Organic Chemistry. PMID 27442351 DOI: 10.1021/acs.joc.6b01369  1
2016 Wang Z, Krogsgaard-Larsen N, Daniels B, Furkert DP, Brimble MA. Cyclic Enecarbamates as Precursors of alpha,beta-Unsaturated Iminium Ions: Reactivity and Synthesis of 6,6-Spirocyclic Ring Systems. The Journal of Organic Chemistry. PMID 27441647 DOI: 10.1021/acs.joc.6b01343  1
2016 Yim V, Noisier AF, Hung KY, Bartsch JW, Schlomann U, Brimble MA. Synthesis and biological evaluation of analogues of the potent ADAM8 inhibitor cyclo(RLsKDK) for the treatment of inflammatory diseases and cancer metastasis. Bioorganic & Medicinal Chemistry. PMID 27407033 DOI: 10.1016/j.bmc.2016.06.042  0.36
2016 Singh-Mallah G, Singh K, McMahon CD, Harris P, Brimble MA, Thorstensen E, Guan J. Maternally administered cyclic-glycine-proline increases insulin-like growth factor-1 bioavailability and novelty recognition in developing offspring. Endocrinology. en20161189. PMID 27355491 DOI: 10.1210/en.2016-1189  1
2016 Zhang S, Amso Z, De Leon Rodriguez LM, Kaur H, Brimble MA. Synthesis of Natural Cyclopentapeptides Isolated from Dianthus chinensis. Journal of Natural Products. PMID 27326468 DOI: 10.1021/acs.jnatprod.6b00152  1
2016 De Leon Rodriguez LM, Hemar Y, Cornish J, Brimble MA. Structure-mechanical property correlations of hydrogel forming β-sheet peptides. Chemical Society Reviews. PMID 27301699 DOI: 10.1039/c5cs00941c  1
2016 Amso Z, Cornish J, Brimble MA. Short Anabolic Peptides for Bone Growth. Medicinal Research Reviews. 36: 579-640. PMID 27297498 DOI: 10.1002/med.21388  1
2016 Eurtivong C, Reynisdóttir I, Kuczma S, Furkert DP, Brimble MA, Reynisson J. Identification of anticancer agents based on the thieno[2,3-b]pyridine and 1H-pyrazole molecular scaffolds. Bioorganic & Medicinal Chemistry. PMID 27288184 DOI: 10.1016/j.bmc.2016.05.061  1
2016 Amso Z, Kowalczyk R, Park YE, Watson M, Lin JM, Musson DS, Cornish J, Brimble MA. Synthesis and in vitro bone cell activity of analogues of the cyclohexapeptide dianthin G. Organic & Biomolecular Chemistry. PMID 27264279 DOI: 10.1039/c6ob00983b  1
2016 Daniels BJ, Prijic G, Meidinger S, Loomes KM, Stephens JM, Schlothauer RC, Furkert DP, Brimble MA. Isolation, Structural Elucidation and Synthesis of Lepteridine from Mānuka Honey. Journal of Agricultural and Food Chemistry. PMID 27210444 DOI: 10.1021/acs.jafc.6b01596  1
2016 Yeung H, Squire CJ, Yosaatmadja Y, Panjikar S, López G, Molina A, Baker EN, Harris PW, Brimble MA. Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily. Angewandte Chemie (International Ed. in English). PMID 27145301 DOI: 10.1002/anie.201602719  1
2016 Choi H, Conole D, Atkinson DJ, Laita O, Jay-Smith M, Pagano MA, Ribaudo G, Cavalli M, Bova S, Hopkins B, Brimble MA, Rennison D. Fatty Acid Derived Pro-toxicants of the Rat Selective Toxicant Norbormide. Chemistry & Biodiversity. PMID 27144301 DOI: 10.1002/cbdv.201500241  1
2016 Yule LR, Bower RL, Kaur H, Kowalczyk R, Hay DL, Brimble MA. Synthesis and amylin receptor activity of glycomimetics of pramlintide using click chemistry. Organic & Biomolecular Chemistry. PMID 27139251 DOI: 10.1039/c6ob00850j  0.48
2016 Watkins HA, Chakravarthy M, Abhayawardana RS, Gingell JJ, Garelja M, Pardamwar M, McElhinney JM, Lathbridge A, Constantine A, Harris PW, Yuen TY, Brimble MA, Barwell J, Poyner DR, Woolley MJ, et al. Receptor Activity-Modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties. The Journal of Biological Chemistry. PMID 27013657 DOI: 10.1074/jbc.M115.688218  1
2016 Son SJ, Harris PW, Squire CJ, Baker EN, Brimble MA. Synthesis and structural insight into ESX-1 substrate protein C (EspC), an immunodominant Mycobacterium tuberculosis-secreted antigen. Biopolymers. PMID 26999334 DOI: 10.1002/bip.22838  1
2016 De Leon-Rodriguez LM, Kamalov M, Hemar Y, Mitra AK, Castelletto V, Hermida-Merino D, Hamley IW, Brimble MA. A peptide hydrogel derived from a fragment of human cardiac troponin C. Chemical Communications (Cambridge, England). PMID 26892840 DOI: 10.1039/c6cc00209a  1
2016 Ding XB, Brimble MA, Furkert DP. Nitropyrrole natural products: isolation, biosynthesis and total synthesis. Organic & Biomolecular Chemistry. PMID 26879381 DOI: 10.1039/c5ob02599k  1
2016 Ting YT, Harris PW, Batot G, Brimble MA, Baker EN, Young PG. Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization. Iucrj. 3: 10-9. PMID 26870377 DOI: 10.1107/S2052252515019971  1
2016 Jamieson ML, Hume PA, Furkert DP, Brimble MA. Divergent Reactivity via Cobalt Catalysis: An Epoxide Olefination. Organic Letters. 18: 468-71. PMID 26829490 DOI: 10.1021/acs.orglett.5b03514  1
2016 Kamalov M, Kaur H, Brimble MA. Intermolecular Peptide Cross-Linking by Using Diaminodicarboxylic Acids. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26749083 DOI: 10.1002/chem.201503458  1
2016 Dolan C, Drouet F, Ware DC, Brothers PJ, Jin J, Brimble MA, Williams DE. A new high-capacity metal ion-complexing gel containing cyclen ligands Rsc Advances. 6: 23645-23652. DOI: 10.1039/c6ra00604c  1
2016 Medini K, Harris PWR, Menorca A, Hards K, Cook GM, Brimble MA. Synthesis and activity of a diselenide bond mimetic of the antimicrobial protein caenopore-5 Chemical Science. 7: 2005-2010. DOI: 10.1039/c5sc04187b  1
2016 Dickson E, Pilkington LI, Brimble MA, Barker D. Enantioselective synthesis of BE ring analogues of methyllycaconitine Tetrahedron. 72: 400-414. DOI: 10.1016/j.tet.2015.11.057  1
2016 Strover LT, Malmström J, Stubbing LA, Brimble MA, Travas-Sejdic J. Electrochemically-controlled grafting of hydrophilic brushes from conducting polymer substrates Electrochimica Acta. 188: 57-70. DOI: 10.1016/j.electacta.2015.11.106  1
2016 Amso Z, Cornish J, Brimble MA. Short Anabolic Peptides for Bone Growth Medicinal Research Reviews. DOI: 10.1002/med.21388  1
2016 Li FF, Atkinson DJ, Furkert DP, Brimble MA. A Convergent Synthesis of Gonytolide C Using an Intramolecular Oxa-Michael Addition European Journal of Organic Chemistry. 2016: 1145-1155. DOI: 10.1002/ejoc.201501402  1
2016 Yang SH, Harris PWR, Williams GM, Brimble MA. Lipidation of Cysteine or Cysteine-Containing Peptides Using the Thiol-Ene Reaction (CLipPA) European Journal of Organic Chemistry. DOI: 10.1002/ejoc.201501375  1
2016 Chorley DF, Furkert DP, Brimble MA. Synthesis of the Spiroketal Core of the Pinnatifinoside Family of Natural Products European Journal of Organic Chemistry. 2016: 314-319. DOI: 10.1002/ejoc.201501225  1
2015 Anderson RJ, Compton BJ, Tang CW, Authier-Hall A, Hayman CM, Swinerd GW, Kowalczyk R, Harris P, Brimble MA, Larsen DS, Gasser O, Weinkove R, Hermans IF, Painter GF. NKT cell-dependent glycolipid-peptide vaccines with potent anti-tumour activity. Chemical Science. 6: 5120-5127. PMID 28717498 DOI: 10.1039/c4sc03599b  0.44
2015 McIntosh JD, Brimble MA, Brooks AES, Dunbar PR, Kowalczyk R, Tomabechi Y, Fairbanks AJ. Convergent chemo-enzymatic synthesis of mannosylated glycopeptides; targeting of putative vaccine candidates to antigen presenting cells. Chemical Science. 6: 4636-4642. PMID 28717478 DOI: 10.1039/c5sc00952a  0.44
2015 Panwalkar V, Neudecker P, Schmitz M, Lecher J, Schulte M, Medini K, Stoldt M, Brimble MA, Willbold D, Dingley AJ. The Nedd4-1 WW domain recognizes the PY motif peptide through a coupled folding-binding equilibrium. Biochemistry. PMID 26685112 DOI: 10.1021/acs.biochem.5b01028  1
2015 Kamato D, Thach L, Bernard R, Chan V, Zheng W, Kaur H, Brimble M, Osman N, Little PJ. Structure, Function, Pharmacology, and Therapeutic Potential of the G Protein, Gα/q,11. Frontiers in Cardiovascular Medicine. 2: 14. PMID 26664886 DOI: 10.3389/fcvm.2015.00014  0.48
2015 Poral VL, Furkert DP, Brimble MA. Total Synthesis and Structural Confirmation of the Antimalarial Naphthopyrone Lasionectrin. Organic Letters. 17: 6214-7. PMID 26650711 DOI: 10.1021/acs.orglett.5b03202  1
2015 De Leon Rodriguez LM, Kaur H, Brimble MA. Synthesis and bioactivity of antitubercular peptides and peptidomimetics: an update. Organic & Biomolecular Chemistry. PMID 26645944 DOI: 10.1039/c5ob02298c  1
2015 Ko KY, Wagner S, Yang SH, Furkert DP, Brimble MA. Improved Synthesis of the Unnatural Amino Acids AHMOD and AMD, Components of the Anticancer Peptaibol Culicinin D. The Journal of Organic Chemistry. PMID 26252224 DOI: 10.1021/acs.joc.5b01265  1
2015 Hampe L, Radjainia M, Xu C, Harris PW, Bashiri G, Goldstone DC, Brimble MA, Wang Y, Mitra AK. Regulation and Quality Control of Adiponectin Assembly by Endoplasmic Reticulum Chaperone ERp44. The Journal of Biological Chemistry. 290: 18111-23. PMID 26060250 DOI: 10.1074/jbc.M115.663088  1
2015 De Leon Rodriguez LM, Weidkamp AJ, Brimble MA. An update on new methods to synthesize cyclotetrapeptides. Organic & Biomolecular Chemistry. 13: 6906-21. PMID 26022908 DOI: 10.1039/c5ob00880h  1
2015 Booe JM, Walker CS, Barwell J, Kuteyi G, Simms J, Jamaluddin MA, Warner ML, Bill RM, Harris PW, Brimble MA, Poyner DR, Hay DL, Pioszak AA. Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor. Molecular Cell. 58: 1040-52. PMID 25982113 DOI: 10.1016/j.molcel.2015.04.018  1
2015 Papst S, Brimble MA, Evans CW, Verdon DJ, Feisst V, Dunbar PR, Tilley RD, Williams DE. Cell-targeted platinum nanoparticles and nanoparticle clusters. Organic & Biomolecular Chemistry. 13: 6567-72. PMID 25978133 DOI: 10.1039/c5ob00822k  1
2015 Kamalov M, Harris PW, Wood JM, Brimble MA. On resin synthesis and cross-linking of collagen peptides containing the advanced glycation end-product pyrraline via Maillard condensation. Chemical Communications (Cambridge, England). 51: 9475-8. PMID 25963401 DOI: 10.1039/c5cc03052h  1
2015 Brings S, Zhang S, Choong YS, Hogl S, Middleditch M, Kamalov M, Brimble MA, Gong D, Cooper GJ. Diabetes-induced alterations in tissue collagen and carboxymethyllysine in rat kidneys: Association with increased collagen-degrading proteinases and amelioration by Cu(II)-selective chelation. Biochimica Et Biophysica Acta. 1852: 1610-8. PMID 25900786 DOI: 10.1016/j.bbadis.2015.04.014  1
2015 Atkinson DJ, Brimble MA. Isolation, biological activity, biosynthesis and synthetic studies towards the rubromycin family of natural products. Natural Product Reports. 32: 811-40. PMID 25798711 DOI: 10.1039/c4np00153b  1
2015 Williams GM, Lee K, Li X, Cooper GJ, Brimble MA. Replacement of the CysA7-CysB7 disulfide bond with a 1,2,3-triazole linker causes unfolding in insulin glargine. Organic & Biomolecular Chemistry. 13: 4059-63. PMID 25731597 DOI: 10.1039/c5ob00160a  1
2015 Hubert JG, Furkert DP, Brimble MA. Synthesis of the spirocyclic framework of sesterterpenoid natural products. The Journal of Organic Chemistry. 80: 2715-23. PMID 25658583 DOI: 10.1021/jo502897u  1
2015 Guan J, Harris P, Brimble M, Lei Y, Lu J, Yang Y, Gunn AJ. The role for IGF-1-derived small neuropeptides as a therapeutic target for neurological disorders. Expert Opinion On Therapeutic Targets. 19: 785-93. PMID 25652713 DOI: 10.1517/14728222.2015.1010514  1
2015 Hubert JG, Furkert DP, Brimble MA. Preparation of cis-γ-hydroxycarvone derivatives for synthesis of sesterterpenoid natural products: total synthesis of phorbin A. The Journal of Organic Chemistry. 80: 2231-9. PMID 25630043 DOI: 10.1021/jo502748s  1
2015 Kamalov M, Harris PW, Hartinger CG, Miskelly GM, Cooper GJ, Brimble MA. Physicochemical studies on the copper(II) binding by glycated collagen telopeptides. Organic & Biomolecular Chemistry. 13: 3058-63. PMID 25622575 DOI: 10.1039/c4ob02536a  1
2015 Brimble MA, Edwards PJ, Harris PW, Norris GE, Patchett ML, Wright TH, Yang SH, Carley SE. Synthesis of the antimicrobial S-linked glycopeptide, glycocin F. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 3556-61. PMID 25607533 DOI: 10.1002/chem.201405692  1
2015 Kaur H, Harris PW, Little PJ, Brimble MA. Total synthesis of the cyclic depsipeptide YM-280193, a platelet aggregation inhibitor. Organic Letters. 17: 492-5. PMID 25590672 DOI: 10.1021/ol503507g  1
2015 Lee KL, Middleditch MJ, Williams GM, Brimble MA, Cooper GJ. Using mass spectrometry to detect, differentiate, and semiquantitate closely related peptide hormones in complex milieu: measurement of IGF-II and vesiculin. Endocrinology. 156: 1194-9. PMID 25545381 DOI: 10.1210/en.2014-1593  1
2015 Harris PW, Squire C, Young PG, Brimble MA. Chemical synthesis of γ-secretase activating protein using pseudoglutamines as ligation sites. Biopolymers. 104: 37-45. PMID 25523549 DOI: 10.1002/bip.22600  1
2015 Wadsworth AD, Naysmith BJ, Brimble MA. A review of the synthesis of α-carbolines. European Journal of Medicinal Chemistry. 97: 816-29. PMID 25499235 DOI: 10.1016/j.ejmech.2014.11.038  1
2015 Medini K, Harris PW, Hards K, Dingley AJ, Cook GM, Brimble MA. Chemical synthesis of a pore-forming antimicrobial protein, caenopore-5, by using native chemical ligation at a glu-cys site. Chembiochem : a European Journal of Chemical Biology. 16: 328-36. PMID 25425108 DOI: 10.1002/cbic.201402513  1
2015 Mellor KM, Brimble MA, Delbridge LM. Glucose as an agent of post-translational modification in diabetes--New cardiac epigenetic insights. Life Sciences. 129: 48-53. PMID 24699006 DOI: 10.1016/j.lfs.2014.03.020  1
2015 Dolan C, Naysmith B, Hinkley SFR, Sims IM, Brimble MA, Williams DE, Jin J. Synthesis of novel triazole-containing phosphonate polymers Australian Journal of Chemistry. 68: 680-686. DOI: 10.1071/CH14513  1
2015 McIntosh JD, Brimble MA, Brooks AES, Dunbar PR, Kowalczyk R, Tomabechi Y, Fairbanks AJ. Convergent chemo-enzymatic synthesis of mannosylated glycopeptides; targeting of putative vaccine candidates to antigen presenting cells Chemical Science. 6: 4636-4642. DOI: 10.1039/c5sc00952a  1
2015 Anderson RJ, Compton BJ, Tang CW, Authier-Hall A, Hayman CM, Swinerd GW, Kowalczyk R, Harris P, Brimble MA, Larsen DS, Gasser O, Weinkove R, Hermans IF, Painter GF. NKT cell-dependent glycolipid-peptide vaccines with potent anti-tumour activity Chemical Science. 6: 5120-5127. DOI: 10.1039/c4sc03599b  1
2015 Robinson E, Leung E, Matuszek AM, Krogsgaard-Larsen N, Furkert DP, Brimble MA, Richardson A, Reynisson J. Virtual screening for novel Atg5-Atg16 complex inhibitors for autophagy modulation Medchemcomm. 6: 239-246. DOI: 10.1039/c4md00420e  1
2015 Sparrow KJ, Carley S, Söhnel T, Barker D, Brimble MA. Studies towards development of asymmetric double-Mannich reactions of chiral 2-oxocyclohexanecarboxylate derivatives with bis(aminol)ethers Tetrahedron. 71: 2210-2221. DOI: 10.1016/j.tet.2015.02.083  1
2015 Atkinson DJ, Furkert DP, Brimble MA. Synthesis of the carbon skeleton of the griseorhodins Tetrahedron. 71: 91-101. DOI: 10.1016/j.tet.2014.11.030  1
2015 Hassan NPS, Naysmith BJ, Sperry J, Brimble MA. Formal synthesis of nanaomycin D via a Hauser-Kraus annulation using a chiral enone-lactone Tetrahedron. 71: 7137-7143. DOI: 10.1016/j.tet.2014.09.014  1
2015 Hume PA, Furkert DP, Brimble MA. Total Synthesis of the Fungal Metabolite Virgatolide B Strategies and Tactics in Organic Synthesis. 11: 119-150. DOI: 10.1016/B978-0-08-100023-6.00005-1  1
2015 Stach M, Weidkamp AJ, Yang SH, Hung KY, Furkert DP, Harris PWR, Smaill JB, Patterson AV, Brimble MA. Improved Strategy for the Synthesis of the Anticancer Agent Culicinin D European Journal of Organic Chemistry. 2015: 6341-6350. DOI: 10.1002/ejoc.201500872  1
2015 Stubbing LA, Lott JS, Dawes SS, Furkert DP, Brimble MA. Synthesis of DOHNAA, a Mycobacterium tuberculosis Cholesterol CD Ring Catabolite and FadD3 Substrate European Journal of Organic Chemistry. 2015: 6075-6083. DOI: 10.1002/ejoc.201500698  1
2014 Wadsworth AD, Furkert DP, Brimble MA. Total synthesis of the macrocyclic N-Methyl enamides palmyrolide A and 2S-sanctolide A. The Journal of Organic Chemistry. 79: 11179-93. PMID 25369466 DOI: 10.1021/jo502238r  1
2014 Young Jeong J, Sperry J, Taylor JA, Brimble MA. Synthesis and evaluation of 9-deoxy analogues of (-)-thysanone, an inhibitor of HRV 3C protease. European Journal of Medicinal Chemistry. 87: 220-7. PMID 25259514 DOI: 10.1016/j.ejmech.2014.09.063  1
2014 Lim D, Brimble MA, Kowalczyk R, Watson AJ, Fairbanks AJ. Protecting-group-free one-pot synthesis of glycoconjugates directly from reducing sugars. Angewandte Chemie (International Ed. in English). 53: 11907-11. PMID 25199905 DOI: 10.1002/anie.201406694  1
2014 Noisier AF, Brimble MA. C-H functionalization in the synthesis of amino acids and peptides. Chemical Reviews. 114: 8775-806. PMID 25144592 DOI: 10.1021/cr500200x  1
2014 Quach R, F Chorley D, Brimble MA. Recent developments in transition metal-catalysed spiroketalisation. Organic & Biomolecular Chemistry. 12: 7423-32. PMID 25137016 DOI: 10.1039/c4ob01325e  1
2014 Kowalczyk R, Brimble MA, Tomabechi Y, Fairbanks AJ, Fletcher M, Hay DL. Convergent chemoenzymatic synthesis of a library of glycosylated analogues of pramlintide: structure-activity relationships for amylin receptor agonism. Organic & Biomolecular Chemistry. 12: 8142-51. PMID 25030939 DOI: 10.1039/c4ob01208a  1
2014 Brimble MA, Hassan NP, Naysmith BJ, Sperry J. Toward an asymmetric synthesis of the dimeric pyranonaphthoquinone antibiotic crisamicin A. The Journal of Organic Chemistry. 79: 7169-78. PMID 25029027 DOI: 10.1021/jo501344c  1
2014 Kowalczyk R, Yang SH, Brimble MA, Callon KE, Watson M, Park YE, Cornish J. Synthesis of truncated analogues of preptin-(1–16), and investigation of their ability to stimulate osteoblast proliferation. Bioorganic & Medicinal Chemistry. 22: 3565-72. PMID 24932835 DOI: 10.1016/j.bmc.2014.05.026  1
2014 Young PG, Proft T, Harris PW, Brimble MA, Baker EN. Structure and activity of Streptococcus pyogenes SipA: a signal peptidase-like protein essential for pilus polymerisation. Plos One. 9: e99135. PMID 24911348 DOI: 10.1371/journal.pone.0099135  1
2014 Hume PA, Furkert DP, Brimble MA. Total synthesis of virgatolide B via exploitation of intramolecular hydrogen bonding. The Journal of Organic Chemistry. 79: 5269-81. PMID 24836848 DOI: 10.1021/jo5008527  1
2014 Harris PW, Hampe L, Radjainia M, Brimble MA, Mitra AK. An investigation of the role of the adiponectin variable domain on the stability of the collagen-like domain. Biopolymers. 101: 313-21. PMID 24752567 DOI: 10.1002/bip.22501  1
2014 Kamalov M, Harris PW, Cooper GJ, Brimble MA. Site-specific cross-linking of collagen peptides by lysyl advanced glycation endproducts. Chemical Communications (Cambridge, England). 50: 4944-6. PMID 24705519 DOI: 10.1039/c4cc02003k  1
2014 Yeung H, Harris PW, Squire CJ, Baker EN, Brimble MA. Preparation of truncated orf virus entry fusion complex proteins by chemical synthesis. Journal of Peptide Science : An Official Publication of the European Peptide Society. 20: 398-405. PMID 24652714 DOI: 10.1002/psc.2627  1
2014 Harris PW, Yang SH, Molina A, López G, Middleditch M, Brimble MA. Plant antimicrobial peptides snakin-1 and snakin-2: chemical synthesis and insights into the disulfide connectivity. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 5102-10. PMID 24644073 DOI: 10.1002/chem.201303207  1
2014 Conole D, Beck TM, Jay-Smith M, Tingle MD, Eason CT, Brimble MA, Rennison D. Synthesis and methemoglobinemia-inducing properties of benzocaine isosteres designed as humane rodenticides. Bioorganic & Medicinal Chemistry. 22: 2220-35. PMID 24602400 DOI: 10.1016/j.bmc.2014.02.013  1
2014 Harris PW, Kowalczyk R, Yang SH, Williams GM, Brimble MA. An important side reaction using the thiol, 3,6-dioxa-1,8-octanedithiol (DODT), in 9-fluorenylmethoxycarbonyl-based solid phase peptide synthesis. Journal of Peptide Science : An Official Publication of the European Peptide Society. 20: 186-90. PMID 24353069 DOI: 10.1002/psc.2595  1
2014 Ding XB, Furkert DP, Capon RJ, Brimble MA. Total synthesis of heronapyrrole C. Organic Letters. 16: 378-81. PMID 24351092 DOI: 10.1021/ol403246j  1
2014 Schünemann K, Furkert DP, Choi EC, Connelly S, Fraser JD, Sperry J, Brimble MA. Synthesis of the 2-methylene analogue of the HRV 3C protease inhibitor thysanone (2-carbathysanone). Organic & Biomolecular Chemistry. 12: 905-12. PMID 24346589 DOI: 10.1039/c3ob41951g  1
2014 Hay DL, Harris PW, Kowalczyk R, Brimble MA, Rathbone DL, Barwell J, Conner AC, Poyner DR. Structure-activity relationships of the N-terminus of calcitonin gene-related peptide: key roles of alanine-5 and threonine-6 in receptor activation. British Journal of Pharmacology. 171: 415-26. PMID 24125506 DOI: 10.1111/bph.12464  1
2014 Harris P, Molenaar GT, Amso Z, Savage GP, Brimble MA. An Efficient Fmoc Solid-Phase Synthesis of an Amphiphile of the Neuroprotective Agent Glycyl-prolyl-glutamic Acid Synlett. DOI: 10.1055/s-0034-1378539  1
2014 Kamalov M, Yang S, Harris PWR, Cooper GJS, Brimble MA. Expedient synthesis of peptides containing Nε- carboxymethyllysine Synlett. 25: 1835-1838. DOI: 10.1055/s-0033-1378305  1
2014 Schünemann K, Furkert DP, Connelly S, Fraser JD, Sperry J, Brimble MA. Iridium-catalysed C-H borylation facilitates a total synthesis of the HRV 3C protease inhibitor (±)-thysanone Synlett. 25: 556-558. DOI: 10.1055/s-0033-1340495  1
2014 Kaur H, Heapy AM, Kowalczyk R, Amso Z, Watson M, Cornish J, Brimble MA. Synthesis and biological evaluation of the osteoblast proliferating cyclic peptides dianthins G and H Tetrahedron. 70: 7788-7794. DOI: 10.1016/j.tet.2014.04.035  1
2014 Naysmith BJ, Furkert D, Brimble MA. Synthesis of highly substituted pyranonaphthalene spiroketals related to the griseusins using a Hauser-Kraus annulation strategy Tetrahedron. 70: 1199-1206. DOI: 10.1016/j.tet.2013.12.066  1
2014 Finch OC, Furkert DP, Brimble MA. Synthesis of the spiroacetal core of the cephalosporolide family of natural products Tetrahedron. 70: 590-596. DOI: 10.1016/j.tet.2013.12.012  1
2014 Papst S, Brimble MA, Tilley RD, Williams DE. One-pot synthesis of functionalized noble metal nanoparticles using a rationally designed phosphopeptide Particle and Particle Systems Characterization. 31: 971-975. DOI: 10.1002/ppsc.201300381  1
2014 Furkert DP, Breitenbach B, Juen L, Sroka I, Pantin M, Brimble MA. Nonsymmetrical azocarbonamide carboxylates as effective Mitsunobu reagents European Journal of Organic Chemistry. 2014: 7806-7809. DOI: 10.1002/ejoc.201403152  1
2014 Geng HM, Stubbing LA, Li-yang Chen J, Furkert DP, Brimble MA. Synthesis of the revised structure of acortatarin A European Journal of Organic Chemistry. DOI: 10.1002/ejoc.201403000  1
2014 Drouet F, Noisier AFM, Harris CS, Furkert DP, Brimble MA. A convenient method for the asymmetric synthesis of fluorinated α-amino acids from alcohols European Journal of Organic Chemistry. 2014: 1195-1201. DOI: 10.1002/ejoc.201301718  1
2014 Yuen TY, Eaton SE, Woods TM, Furkert DP, Choi KW, Brimble MA. A Maillard approach to 2-formylpyrroles: Synthesis of magnolamide, lobechine and funebral European Journal of Organic Chemistry. 2014: 1431-1437. DOI: 10.1002/ejoc.201301639  1
2014 Schünemann K, Furkert DP, Connelly S, Fraser JD, Sperry J, Brimble MA. Synthesis and biological evaluation of 7-deoxy analogues of the human rhinovirus 3c protease inhibitor thysanone European Journal of Organic Chemistry. 2014: 122-128. DOI: 10.1002/ejoc.201301515  1
2014 Son SJ, Harris PWR, Squire CJ, Baker EN, Kent SBH, Brimble MA. Total chemical synthesis of an Orf virus protein, ORFV002, an inhibitor of the master gene regulator NF-κB Biopolymers - Peptide Science Section. 102: 137-144. DOI: 10.1002/bip.22445  1
2013 Heapy AM, Patterson AV, Smaill JB, Jamieson SM, Guise CP, Sperry J, Hume PA, Rathwell K, Brimble MA. Synthesis and cytotoxicity of pyranonaphthoquinone natural product analogues under bioreductive conditions. Bioorganic & Medicinal Chemistry. 21: 7971-80. PMID 24436995 DOI: 10.1016/j.bmc.2013.09.052  1
2013 Rennison D, Conole D, Tingle MD, Yang J, Eason CT, Brimble MA. Synthesis and methemoglobinemia-inducing properties of analogues of para-aminopropiophenone designed as humane rodenticides. Bioorganic & Medicinal Chemistry Letters. 23: 6629-35. PMID 24210502 DOI: 10.1016/j.bmcl.2013.10.046  1
2013 Johannes M, Brimble MA. Synthesis of an azido precursor to (2S,5R)-5-hydroxylysine using an asymmetric organocatalytic chlorination/reduction sequence. The Journal of Organic Chemistry. 78: 12809-13. PMID 24175670 DOI: 10.1021/jo402220s  1
2013 Hume PA, Furkert DP, Brimble MA. Total synthesis of virgatolide B. Organic Letters. 15: 4588-91. PMID 23957570 DOI: 10.1021/ol402191t  1
2013 Wright TH, Brooks AE, Didsbury AJ, MacIntosh JD, Williams GM, Harris PW, Dunbar PR, Brimble MA. Direct peptide lipidation through thiol-ene coupling enables rapid synthesis and evaluation of self-adjuvanting vaccine candidates. Angewandte Chemie (International Ed. in English). 52: 10616-9. PMID 23939951 DOI: 10.1002/anie.201305620  1
2013 Rennison D, Laita O, Conole D, Jay-Smith M, Knauf J, Bova S, Cavalli M, Hopkins B, Linthicum DS, Brimble MA. Prodrugs of N-dicarboximide derivatives of the rat selective toxicant norbormide. Bioorganic & Medicinal Chemistry. 21: 5886-99. PMID 23920483 DOI: 10.1016/j.bmc.2013.06.071  1
2013 Noisier AF, Harris CS, Brimble MA. Novel preparation of chiral α-amino acids using the Mitsunobu-Tsunoda reaction. Chemical Communications (Cambridge, England). 49: 7744-6. PMID 23877629 DOI: 10.1039/c3cc44717k  1
2013 Aitken HR, Furkert DP, Hubert JG, Wood JM, Brimble MA. Enantioselective access to benzannulated spiroketals using a chiral sulfoxide auxiliary. Organic & Biomolecular Chemistry. 11: 5147-55. PMID 23817587 DOI: 10.1039/c3ob41065j  1
2013 Yang SH, Wojnar JM, Harris PW, DeVries AL, Evans CW, Brimble MA. Chemical synthesis of a masked analogue of the fish antifreeze potentiating protein (AFPP). Organic & Biomolecular Chemistry. 11: 4935-42. PMID 23788006 DOI: 10.1039/c3ob41066h  1
2013 Bobby R, Medini K, Neudecker P, Lee TV, Brimble MA, McDonald FJ, Lott JS, Dingley AJ. Structure and dynamics of human Nedd4-1 WW3 in complex with the αENaC PY motif. Biochimica Et Biophysica Acta. 1834: 1632-41. PMID 23665454 DOI: 10.1016/j.bbapap.2013.04.031  1
2013 Woods TM, Cooper GJ, Brimble MA. Synthesis of stable isotope-labelled monolysyl advanced glycation endproducts. Amino Acids. 45: 319-25. PMID 23588492 DOI: 10.1007/s00726-013-1498-9  1
2013 Papst S, Cheong S, Banholzer MJ, Brimble MA, Williams DE, Tilley RD. One-pot synthesis of water soluble iron nanoparticles using rationally-designed peptides and ligand release. Chemical Communications (Cambridge, England). 49: 4540-2. PMID 23576141 DOI: 10.1039/c3cc41751d  1
2013 Naysmith BJ, Brimble MA. Synthesis of the griseusin B framework via a one-pot annulation-methylation-double deprotection-spirocyclization sequence. Organic Letters. 15: 2006-9. PMID 23560611 DOI: 10.1021/ol400686f  1
2013 Williams GM, Cooper GJ, Lee K, Whiting L, Brimble MA. Synthesis of the IGF-II-like hormone vesiculin using regioselective formation of disulfide bonds. Organic & Biomolecular Chemistry. 11: 3145-50. PMID 23538787 DOI: 10.1039/c3ob40322j  1
2013 Kueh JT, Choi KW, Williams GM, Moehle K, Bacsa B, Robinson JA, Brimble MA. Synthesis of a 6,6-spiroketal amino acid and its incorporation into a peptide turn sequence using solid-phase peptide synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 3807-11. PMID 23424080 DOI: 10.1002/chem.201204546  1
2013 Watkins HA, Au M, Bobby R, Archbold JK, Abdul-Manan N, Moore JM, Middleditch MJ, Williams GM, Brimble MA, Dingley AJ, Hay DL. Identification of key residues involved in adrenomedullin binding to the AM1 receptor British Journal of Pharmacology. 169: 143-155. PMID 23351143 DOI: 10.1111/bph.12118  1
2013 Kim UB, Furkert DP, Brimble MA. Total synthesis of chaetoquadrins A-C. Organic Letters. 15: 658-61. PMID 23327616 DOI: 10.1021/ol303482k  1
2013 Stubbing LA, Savage GP, Brimble MA. N-alkylsulfonylimines as dipolarophiles in cycloaddition reactions. Chemistry, An Asian Journal. 8: 42-8. PMID 22945869 DOI: 10.1002/asia.201200584  1
2013 Brimble MA, Black DS, Hartshorn R, Rauter AP, Sha CK, Sydnes LK. Rules for abbreviation of protecting groups (IUPAC technical report) Pure and Applied Chemistry. 85: 307-313. DOI: 10.1351/PAC-REP-12-07-12  1
2013 Yuen TY, Ng YP, Ip FCF, Chen JLY, Atkinson DJ, Sperry J, Ip NY, Brimble MA. Telomerase inhibition studies of novel spiroketal-containing rubromycin derivatives Australian Journal of Chemistry. 66: 530-533. DOI: 10.1071/CH13035  1
2013 Bridewell DJA, Sperry J, Smith JR, Kosim-Satyaputra P, Ching LM, Jamie JF, Brimble MA. Natural product-inspired pyranonaphthoquinone inhibitors of indoleamine 2,3-dioxygenase-1 (IDO-1)* Australian Journal of Chemistry. 66: 40-49. DOI: 10.1071/CH12393  1
2013 Son SJ, Brimble MA, Yang S, Harris PWR, Reddingius T, Muir BW, Hutt OE, Waddington L, Guan J, Savage GP. Synthesis and self-assembly of a peptide-amphiphile as a drug delivery vehicle Australian Journal of Chemistry. 66: 23-29. DOI: 10.1071/CH12347  1
2013 Wright TH, Brooks AES, Didsbury AJ, McIntosh JD, Burkert K, Yeung H, Williams GM, Dunbar PR, Brimble MA. An improved method for the synthesis of lipopeptide TLR2-agonists using click chemistry Synlett. 24: 1835-1841. DOI: 10.1055/s-0033-1339349  1
2013 Heapy AM, Dragunow M, Brimble MA. Synthesis of the cysteine protease inhibitors CPI-2081a and CPI-2081b using a controlled SPPS byproduct forming reaction Synlett. 24: 1818-1824. DOI: 10.1055/s-0033-1339347  1
2013 Kim UB, Dalebrook AF, Furkert DP, Brimble MA. Total synthesis of chaetoquadrins H and i Synlett. 24: 723-726. DOI: 10.1055/s-0032-1318333  1
2013 Charville H, Jin J, Evans CW, Brimble MA, Williams DE. The synthesis and lectin-binding properties of novel mannose-functionalised polymers Rsc Advances. 3: 15435-15441. DOI: 10.1039/c3ra42781a  1
2013 Malmström J, Nieuwoudt MK, Strover LT, Hackett A, Laita O, Brimble MA, Williams DE, Travas-Sejdic J. Grafting from poly(3,4-ethylenedioxythiophene): A simple route to versatile electrically addressable surfaces Macromolecules. 46: 4955-4965. DOI: 10.1021/ma400803j  1
2013 Aitken HRM, Johannes M, Loomes KM, Brimble MA. Synthesis of leptosin, a glycoside isolated from mānuka honey Tetrahedron Letters. 54. DOI: 10.1016/j.tetlet.2013.10.042  1
2013 Quach R, Furkert DP, Brimble MA. Synthesis of benzannulated spiroacetals using chiral gold-phosphine complexes and chiral anions Tetrahedron Letters. 54: 5865-5868. DOI: 10.1016/j.tetlet.2013.08.077  1
2013 Strover LT, Malmström J, Laita O, Reynisson J, Aydemir N, Nieuwoudt MK, Williams DE, Dunbar PR, Brimble MA, Travas-Sejdic J. A new precursor for conducting polymer-based brush interfaces with electroactivity in aqueous solution Polymer (United Kingdom). 54: 1305-1317. DOI: 10.1016/j.polymer.2012.11.083  1
2013 Hume PA, Brimble MA, Reynisson J. DNA adduct formation of mitomycin C. A test case for DFT calculations on model systems Computational and Theoretical Chemistry. 1005: 9-15. DOI: 10.1016/j.comptc.2012.10.022  1
2013 Harris PWR, Kowalczyk R, Hay DL, Brimble MA. A single pseudoproline and microwave solid phase peptide synthesis facilitates an efficient synthesis of human amylin 1-37 International Journal of Peptide Research and Therapeutics. 19: 147-155. DOI: 10.1007/s10989-012-9325-9  1
2013 Wojnar JM, Lee DJ, Evans CW, Mandal K, Kent SBH, Brimble MA. Neoglycoprotein Synthesis Using the Copper-Catalyzed Azide-Alkyne Click Reaction and Native Chemical Ligation Click Chemistry in Glycoscience: New Developments and Strategies. 251-270. DOI: 10.1002/9781118526996.ch10  1
2012 Brimble MA, Haym I, Sperry J, Furkert DP. Synthesis of the tetracyclic core of berkelic acid using gold(I)-catalyzed hydroarylation and oxidative radical cyclizations. Organic Letters. 14: 5820-3. PMID 23186011 DOI: 10.1021/ol302536j  1
2012 Hung KY, Harris PW, Brimble MA. Synthesis of the peptaibol framework of the anticancer agent culicinin D: stereochemical assignment of the AHMOD moiety. Organic Letters. 14: 5784-7. PMID 23126283 DOI: 10.1021/ol302852q  1
2012 Woods TM, Kamalov M, Harris PW, Cooper GJ, Brimble M. Synthesis of monolysyl advanced glycation endproducts and their incorporation into collagen model peptides. Organic Letters. 14: 5740-3. PMID 23116133 DOI: 10.1021/ol302745f  1
2012 Wadsworth AD, Furkert DP, Sperry J, Brimble MA. Total synthesis of the initially reported and revised structures of the neuroprotective agent palmyrolide A. Organic Letters. 14: 5374-7. PMID 23046111 DOI: 10.1021/ol3025956  1
2012 Yuen TY, Brimble MA. Total synthesis of 7',8'-dihydroaigialospirol. Organic Letters. 14: 5154-7. PMID 23016996 DOI: 10.1021/ol302498v  1
2012 Kowalczyk R, Brimble MA, Callon KE, Watson M, Cornish J. How to blast osteoblasts? Novel dicarba analogues of amylin-(1-8) to treat osteoporosis. Bioorganic & Medicinal Chemistry. 20: 6011-8. PMID 22998786 DOI: 10.1016/j.bmc.2012.08.053  1
2012 Haym I, Brimble MA. The Kulinkovich hydroxycyclopropanation reaction in natural product synthesis. Organic & Biomolecular Chemistry. 10: 7649-65. PMID 22886040 DOI: 10.1039/c2ob26082d  1
2012 Papst S, Noisier AF, Brimble MA, Yang Y, Krissansen GW. Synthesis and biological evaluation of tyrosine modified analogues of the α4β7 integrin inhibitor biotin-R₈ERY. Bioorganic & Medicinal Chemistry. 20: 5139-49. PMID 22877871 DOI: 10.1016/j.bmc.2012.07.010  1
2012 Lee DJ, Yang SH, Williams GM, Brimble MA. Synthesis of multivalent neoglyconjugates of MUC1 by the conjugation of carbohydrate-centered, triazole-linked glycoclusters to MUC1 peptides using click chemistry. The Journal of Organic Chemistry. 77: 7564-71. PMID 22876975 DOI: 10.1021/jo3013435  1
2012 Harris PW, Lee DJ, Brimble MA. A slow gradient approach for the purification of synthetic polypeptides by reversed phase high performance liquid chromatography. Journal of Peptide Science : An Official Publication of the European Peptide Society. 18: 549-55. PMID 22833387 DOI: 10.1002/psc.2432  1
2012 Schünemann K, Connelly S, Kowalczyk R, Sperry J, Wilson IA, Fraser JD, Brimble MA. A simple solid phase, peptide-based fluorescent assay for the efficient and universal screening of HRV 3C protease inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 5018-24. PMID 22763202 DOI: 10.1016/j.bmcl.2012.06.015  1
2012 Rennison D, Laita O, Bova S, Cavalli M, Hopkins B, Linthicum DS, Brimble MA. Design and synthesis of prodrugs of the rat selective toxicant norbormide. Bioorganic & Medicinal Chemistry. 20: 3997-4011. PMID 22658693 DOI: 10.1016/j.bmc.2012.05.014  1
2012 Radjainia M, Huang B, Bai B, Schmitz M, Yang SH, Harris PW, Griffin MD, Brimble MA, Wang Y, Mitra AK. A highly conserved tryptophan in the N-terminal variable domain regulates disulfide bond formation and oligomeric assembly of adiponectin. The Febs Journal. 279: 2495-507. PMID 22583869 DOI: 10.1111/j.1742-4658.2012.08630.x  1
2012 Papst S, Noisier A, Brimble MA, Yang Y, Krissansen GW. Tyrosine modified analogues of the α4β7 integrin inhibitor biotin-R₈ERY prepared via Click Chemistry: synthesis and biological evaluation. Bioorganic & Medicinal Chemistry. 20: 2638-44. PMID 22421276 DOI: 10.1016/j.bmc.2012.02.035  1
2012 Kowalczyk R, Harris PW, Brimble MA, Callon KE, Watson M, Cornish J. Synthesis and evaluation of disulfide bond mimetics of amylin-(1-8) as agents to treat osteoporosis. Bioorganic & Medicinal Chemistry. 20: 2661-8. PMID 22398258 DOI: 10.1016/j.bmc.2012.02.030  1
2012 Heapy AM, Williams GM, Fraser JD, Brimble MA. Synthesis of a dicarba analogue of human β-defensin-1 using a combined ring closing metathesis--native chemical ligation strategy. Organic Letters. 14: 878-81. PMID 22239540 DOI: 10.1021/ol203407z  1
2012 Kueh JT, Choi KW, Brimble MA. Enantioselective synthesis of C-linked spiroacetal-triazoles as privileged natural product-like scaffolds. Organic & Biomolecular Chemistry. 10: 5993-6002. PMID 22237938 DOI: 10.1039/c2ob06802h  1
2012 Herbert KR, Williams GM, Cooper GJ, Brimble MA. Synthesis of glycosylated 5-hydroxylysine, an important amino acid present in collagen-like proteins such as adiponectin. Organic & Biomolecular Chemistry. 10: 1137-44. PMID 22218394 DOI: 10.1039/c1ob06394d  1
2012 McLeod MC, Wilson ZE, Brimble MA. Formal synthesis of berkelic acid: a lesson in α-alkylation chemistry. The Journal of Organic Chemistry. 77: 400-16. PMID 22077770 DOI: 10.1021/jo201988m  1
2012 Mcleod MC, Brimble MA, Rathwell DCK, Wilson ZE, Yuen TY. Synthetic approaches to [5,6]-benzannulated spiroketal natural products Pure and Applied Chemistry. 84: 1379-1390. DOI: 10.1351/PAC-CON-11-08-06  1
2012 Papst S, Noisier AFM, Brimble MA, Yang Y, Chan YC, Krissansen GW. Synthesis and SAR of a library of cell-permeable biotin-R 8ERY*peptidomimetics inhibiting 47 integrin mediated adhesion of TK-1 cells to MAdCAM -1-Fc Australian Journal of Chemistry. 65: 1349-1358. DOI: 10.1071/CH12227  1
2012 Peltier R, Siah WR, Williams GVM, Brimble MA, Tilley RD, Williams DE. Novel phosphopeptides as surface-active agents in iron nanoparticle synthesis Australian Journal of Chemistry. 65: 680-685. DOI: 10.1071/CH12168  1
2012 Hume PA, Brimble MA, Reynisson J. The bioreductive alkylation of DNA by kalafungin: A theoretical investigation Australian Journal of Chemistry. 65: 402-408. DOI: 10.1071/CH12018  1
2012 Kaur H, Heapy AM, Brimble MA. Synthesis of the all-l cyclopentapeptides versicoloritides A, B, and C Synlett. 23: 2284-2288. DOI: 10.1055/s-0032-1316994  1
2012 Yeung H, Lee DJ, Williams GM, Harris PWR, Dunbar RP, Brimble MA. A method for the generation of Pamys-based lipopeptide mimics via CuAAC click chemistry Synlett. 23: 1617-1620. DOI: 10.1055/s-0031-1291148  1
2012 Geng H, Chen JY, Furkert D, Jiang S, Brimble MA. A convergent synthesis of the 2-formylpyrrole spiroketal natural product acortatarin A Synlett. 23: 855-858. DOI: 10.1055/s-0031-1290508  1
2012 Chorley DF, Chen JLY, Furkert DP, Sperry J, Brimble MA. Total synthesis of danshenspiroketallactone Synlett. 128-130. DOI: 10.1055/s-0031-1290082  1
2012 Kaur H, Heapy AM, Brimble MA. Synthesis of the antifungal cyclic peptides tunicyclins C and D Synlett. 275-277. DOI: 10.1055/s-0031-1290071  1
2012 Dimitrov I, Furkert DP, Fraser JD, Radcliff FJ, Finch O, Brimble MA. Synthesis and anti-Helicobacter pylori activity of analogues of spirolaxine methyl ether Medchemcomm. 3: 938-943. DOI: 10.1039/c2md00314g  1
2012 Evans CW, Hellman L, Middleditch M, Wojnar JM, Brimble MA, Devries AL. Synthesis and recycling of antifreeze glycoproteins in polar fishes Antarctic Science. 24: 259-268. DOI: 10.1017/S0954102012000119  1
2012 Hume P, Furkert DP, Brimble MA. Regioselective iridium(I)-catalysed remote borylation of oxygenated naphthalenes Tetrahedron Letters. 53: 3771-3773. DOI: 10.1016/j.tetlet.2012.05.040  1
2012 Stubbing LA, Li FF, Furkert DP, Caprio VE, Brimble MA. Access to 2-alkyl chromanones via a conjugate addition approach Tetrahedron. 68: 6948-6956. DOI: 10.1016/j.tet.2012.05.115  1
2012 Goodall KJ, Brimble MA, Barker D. A tandem Diels-Alder/Mannich approach to the synthesis of AE and ABE ring analogues of Delphinium alkaloids Tetrahedron. 68: 5759-5778. DOI: 10.1016/j.tet.2012.05.037  1
2012 Sparrow K, Barker D, Brimble MA. An efficient synthesis of 3-alkyl-1,5,3-dioxazepanes and their use as electrophiles in double-Mannich reactions Tetrahedron. 68: 1017-1028. DOI: 10.1016/j.tet.2011.11.090  1
2012 Harris PWR, Brimble MA. The chemical synthesis of the collagenous domain of the hormone adiponectin International Journal of Peptide Research and Therapeutics. 18: 63-70. DOI: 10.1007/s10989-011-9279-3  1
2012 Evans CW, Williams DE, Vacchi M, Brimble MA, DeVries AL. Metabolic and behavioural adaptations during early development of the Antarctic silverfish, Pleuragramma antarcticum Polar Biology. 35: 891-898. DOI: 10.1007/s00300-011-1134-7  1
2011 Chen JL, Brimble MA. Synthesis of the bis-spiroacetal core of the antimitotic agent spirastrellolide B. The Journal of Organic Chemistry. 76: 9417-28. PMID 21995770 DOI: 10.1021/jo201729t  1
2011 Yang SH, Lee DJ, Brimble MA. Synthesis of an NDPK phosphocarrier domain peptide containing a novel triazolylalanine analogue of phosphohistidine using click chemistry. Organic Letters. 13: 5604-7. PMID 21939187 DOI: 10.1021/ol202333u  1
2011 McLeod MC, Wilson ZE, Brimble MA. An enantioselective formal synthesis of berkelic acid. Organic Letters. 13: 5382-5. PMID 21916400 DOI: 10.1021/ol202265g  1
2011 Zulian A, Sileikytė J, Petronilli V, Bova S, Dabbeni-Sala F, Cargnelli G, Rennison D, Brimble MA, Hopkins B, Bernardi P, Ricchelli F. The translocator protein (peripheral benzodiazepine receptor) mediates rat-selective activation of the mitochondrial permeability transition by norbormide. Biochimica Et Biophysica Acta. 1807: 1600-5. PMID 21889488 DOI: 10.1016/j.bbabio.2011.08.007  1
2011 Yuen TY, Yang SH, Brimble MA. Total synthesis of paecilospirone. Angewandte Chemie (International Ed. in English). 50: 8350-3. PMID 21780263 DOI: 10.1002/anie.201103117  1
2011 Kaur H, Heapy AM, Brimble MA. The synthesis of dehydrotryptophan and dehydrotryptophan-containing peptides. Organic & Biomolecular Chemistry. 9: 5897-907. PMID 21743891 DOI: 10.1039/c1ob05777d  1
2011 Hume PA, Sperry J, Brimble MA. Enantioselective synthesis of pyranonaphthoquinone antibiotics using a CBS reduction/cross-metathesis/oxa-Michael strategy. Organic & Biomolecular Chemistry. 9: 5423-30. PMID 21655576 DOI: 10.1039/c1ob05595j  1
2011 Lee DJ, Harris PW, Brimble MA. Synthesis of MUC1 Neoglycopeptides using efficient microwave-enhanced chaotrope-assisted click chemistry. Organic & Biomolecular Chemistry. 9: 1621-6. PMID 21249263 DOI: 10.1039/c0ob01043j  1
2011 Hung KY, Harris PW, Heapy AM, Brimble MA. Synthesis and assignment of stereochemistry of the antibacterial cyclic peptide xenematide. Organic & Biomolecular Chemistry. 9: 236-42. PMID 20949214 DOI: 10.1039/c0ob00315h  1
2011 Guéret SM, Brimble MA. Synthetic studies toward the spiroimine unit of the spirolides Pure and Applied Chemistry. 83: 425-433. DOI: 10.1351/PAC-CON-10-09-12  1
2011 Wojnar JM, Evans CW, Devries AL, Brimble MA. Synthesis of an isotopically-labelled antarctic fish antifreeze glycoprotein probe Australian Journal of Chemistry. 64: 723-731. DOI: 10.1071/CH10464  1
2011 Jay-Smith M, Furkert DP, Sperry J, Brimble MA. Efficient synthesis of the spiroacetal core of paecilospirone via oxidative radical cyclisation Synlett. 1395-1398. DOI: 10.1055/s-0030-1260564  1
2011 Sperry J, Liu YC, Wilson ZE, Hubert JG, Brimble MA. Synthesis of benzannulated spiroketals using an oxidative radical cyclization Synthesis. 1383-1398. DOI: 10.1055/s-0030-1259981  1
2011 Atkinson DJ, Sperry J, Brimble MA. Synthesis of benzotriazole analogues of the helicobactericidal agents CJ-13,015, CJ-13,102, CJ-13,108, and CJ-13,104 using a regioselective 1,3-dipolar cycloaddition Synlett. 99-103. DOI: 10.1055/s-0030-1259081  1
2011 Chen JLY, Sperry J, Ip NY, Brimble MA. Natural products targeting telomere maintenance Medchemcomm. 2: 229-245. DOI: 10.1039/c0md00241k  1
2011 Evans CW, Gubala V, Nooney R, Williams DE, Brimble MA, Devries AL. How do Antarctic notothenioid fishes cope with internal ice? A novel function for antifreeze glycoproteins Antarctic Science. 23: 57-64. DOI: 10.1017/S0954102010000635  1
2011 Harris PWR, Yang SH, Brimble MA. An improved procedure for the preparation of aminomethyl polystyrene resin and its use in solid phase (peptide) synthesis Tetrahedron Letters. 52: 6024-6026. DOI: 10.1016/j.tetlet.2011.09.010  1
2011 Zhang YC, Furkert DP, Guéret SM, Lombard F, Brimble MA. Gold(I)-catalysed intramolecular hydroamination of α-quaternary alkynes: Synthetic studies towards spiroimine marine toxins Tetrahedron Letters. 52: 4896-4898. DOI: 10.1016/j.tetlet.2011.07.048  1
2011 Sparrow K, Barker D, Brimble MA. The enantioselective synthesis of tetracyclic methyllycaconitine analogues Tetrahedron. 67: 7989-7999. DOI: 10.1016/j.tet.2011.08.026  1
2011 Brimble MA, Finch OC, Heapy AM, Fraser JD, Furkert DP, O'Connor PD. A convergent synthesis of the [4.4]-spiroacetal-γ-lactones cephalosporolides e and F Tetrahedron. 67: 995-1001. DOI: 10.1016/j.tet.2010.11.107  1
2011 Wilson ZE, Hubert JG, Brimble MA. A flexible approach to 6,5-benzannulated spiroketals European Journal of Organic Chemistry. 3938-3945. DOI: 10.1002/ejoc.201100345  1
2011 Brimble MA, Miller N, Williams GM. Recent Developments in Neoglycopeptide Synthesis Amino Acids, Peptides and Proteins in Organic Chemistry. 4: 359-391. DOI: 10.1002/9783527631827.ch11  1
2010 Guéret SM, Boyd PD, Brimble MA. (1R,6R,13R,18R)-(Z,Z)-1,18-Bis[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-3,16-dimethyl-ene-8,20-diaza-dispiro-[5.6.5.6]tetra-cosa-7,19-diene. Acta Crystallographica. Section E, Structure Reports Online. 66: o1778-9. PMID 21587991 DOI: 10.1107/S1600536810023998  1
2010 Hung KY, Harris PW, Brimble MA. Synthesis of methyl N-Boc-(2S,4R)-4-methylpipecolate. The Journal of Organic Chemistry. 75: 8728-31. PMID 21090804 DOI: 10.1021/jo102038q  1
2010 Guéret SM, Furkert DP, Brimble MA. Synthesis of a functionalized 7,6-bicyclic spiroimine ring fragment of the spirolides. Organic Letters. 12: 5226-9. PMID 21028788 DOI: 10.1021/ol102525w  1
2010 Choi PJ, Sperry J, Brimble MA. Heteroatom-directed reverse Wacker oxidations. Synthesis of the reported structure of (-)-herbaric acid. The Journal of Organic Chemistry. 75: 7388-92. PMID 20873747 DOI: 10.1021/jo1016585  1
2010 Sperry J, Wilson ZE, Rathwell DC, Brimble MA. Isolation, biological activity and synthesis of benzannulated spiroketal natural products. Natural Product Reports. 27: 1117-37. PMID 20648380 DOI: 10.1039/b911514p  1
2010 Harris PW, Brimble MA. Toward the total chemical synthesis of the cancer protein NY-ESO-1. Biopolymers. 94: 542-50. PMID 20593475 DOI: 10.1002/bip.21351  1
2010 Guéret SM, Brimble MA. Spiroimine shellfish poisoning (SSP) and the spirolide family of shellfish toxins: isolation, structure, biological activity and synthesis. Natural Product Reports. 27: 1350-66. PMID 20585694 DOI: 10.1039/c005400n  1
2010 Chen JL, Brimble MA. Synthesis of the bis-spiroacetal C25-C40 moiety of the antimitotic agent spirastrellolide B using a bis-dithiane deprotection/spiroacetalisation sequence. Chemical Communications (Cambridge, England). 46: 3967-9. PMID 20445924 DOI: 10.1039/c0cc00056f  1
2010 Wilson ZE, Brimble MA. A flexible asymmetric synthesis of the tetracyclic core of berkelic acid using a Horner-Wadsworth-Emmons/oxa-Michael cascade. Organic & Biomolecular Chemistry. 8: 1284-6. PMID 20204195 DOI: 10.1039/b927219b  1
2010 Sperry J, Harris EB, Brimble MA. Total synthesis and absolute configuration of (-)-berkeleyamide A. Organic Letters. 12: 420-3. PMID 20030315 DOI: 10.1021/ol902525k  1
2010 Sperry J, Liu YC, Brimble MA. Synthesis of natural products containing spiroketals via intramolecular hydrogen abstraction. Organic & Biomolecular Chemistry. 8: 29-38. PMID 20024126 DOI: 10.1039/b916041h  1
2010 McKay VA, Thompson SJ, Tran PM, Goodall KJ, Brimble MA, Barker D. Stereoselective synthesis of 4-substituted 4-hydroxypiperidines via epoxidation-ring opening of 4-methylenepiperidines Synlett. 2631-2635. DOI: 10.1055/s-0030-1258778  1
2010 Wadsworth AD, Sperry J, Brimble MA. Synthesis of the pyranonaphthoquinones dehydroherbarin, (+)-astropaquinone B and (+)-astropaquinone C en route to ascomycones A and B Synthesis. 2604-2608. DOI: 10.1055/s-0029-1218832  1
2010 Lee DJ, Harris PWR, Kowalczyk R, Dunbar PR, Brimble MA. Microwave-assisted synthesis of fluorescein-labelled GalNAcα1-O-Ser/ Thr (Tn) glycopeptides as immunological probes Synthesis. 763-769. DOI: 10.1055/S-0029-1218635  1
2010 Atkinson DJ, Sperry J, Brimble MA. Improved synthesis of the benzyne precursor 2-(trimethylsilyl)phenyl trifluoromethanesulfonate Synthesis. 911-913. DOI: 10.1055/s-0029-1218631  1
2010 Peltier R, Brimble MA, Wojnar JM, Williams DE, Evans CW, Devries AL. Synthesis and antifreeze activity of fish antifreeze glycoproteins and their analogues Chemical Science. 1: 538-551. DOI: 10.1039/c0sc00194e  1
2010 Peltier R, Evans CW, Devries AL, Brimble MA, Dingley AJ, Williams DE. Growth habit modification of ice crystals using antifreeze glycoprotein (AFGP) analogues Crystal Growth and Design. 10: 5066-5077. DOI: 10.1021/cg1005083  1
2010 Nikac M, Brimble MA, Crumbie RL, Bailey TD. Metal binding studies using spiroacetal thiacrown ethers Tetrahedron Letters. 51: 1072-1074. DOI: 10.1016/j.tetlet.2009.12.110  1
2010 Chan Y, Balle J, Kevin Sparrow J, Boyd PDW, Brimble MA, Barker D. A double Mannich approach to the synthesis of substituted piperidones - Application to the synthesis of substituted E-ring analogues of methyllycaconitine Tetrahedron. 66: 7179-7191. DOI: 10.1016/j.tet.2010.06.084  1
2010 Heapy AM, Brimble MA. Synthesis of the FG ring fragment of pectenotoxins 1-9 Tetrahedron. 66: 5424-5431. DOI: 10.1016/j.tet.2010.05.027  1
2010 Rathwell K, Sperry J, Brimble MA. Synthesis of triazole analogues of the nanaomycin antibiotics using 'click chemistry' Tetrahedron. 66: 4002-4009. DOI: 10.1016/j.tet.2010.04.048  1
2010 Miller N, Williams GM, Brimble MA. Synthesis of neoglycopeptides via click chemistry International Journal of Peptide Research and Therapeutics. 16: 125-132. DOI: 10.1007/s10989-010-9201-4  1
2009 Lee DJ, Mandal K, Harris PW, Brimble MA, Kent SB. A one-pot approach to neoglycopeptides using orthogonal native chemical ligation and click chemistry. Organic Letters. 11: 5270-3. PMID 19842689 DOI: 10.1021/ol902131n  1
2009 Harris PWR, Brimble MA. Synthesis of an arginine tagged [Cys155-Arg180] fragment of NY-ESO-1: elimination of an undesired by-product using 'In house' resins Synthesis. 3460-3466. DOI: 10.1055/s-0029-1216952  1
2004 Brimble MA, Furkert DP. Synthesis of the 1,6,8-trioxadispiro[4.1.5.2]tetradec-11-ene ring system present in the spirolide family of shellfish toxins and its conversion into a 1,6,8-trioxadispiro[4.1.5.2]-tetradec-9-en-12-ol via base-induced rearrangement of an epoxide. Organic & Biomolecular Chemistry. 2: 3573-83. PMID 15592615 DOI: 10.1039/b412883d  1
2002 Furkert DP, Brimble MA. Synthesis of the C10-C22 bis-spiroacetal domain of spirolides B and D via iterative oxidative radical cyclization. Organic Letters. 4: 3655-8. PMID 12375911  1
Show low-probability matches.