Orlando D. Schärer - Publications

Affiliations: 
Chemistry Stony Brook University, Stony Brook, NY, United States 

84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Jeong E, Lee SG, Kim HS, Yang J, Shin J, Kim Y, Kim J, Schärer OD, Kim Y, Yeo JE, Kim HM, Cho Y. Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex. Nucleic Acids Research. PMID 32002546 DOI: 10.1093/nar/gkaa062  0.56
2020 Topolska-Woś AM, Sugitani N, Cordoba JJ, Le Meur KV, Le Meur RA, Kim HS, Yeo JE, Rosenberg D, Hammel M, Schärer OD, Chazin WJ. A key interaction with RPA orients XPA in NER complexes. Nucleic Acids Research. PMID 31925419 DOI: 10.1093/nar/gkz1231  0.56
2019 Raghunandan M, Yeo JE, Walter R, Saito K, Harvey AJ, Ittershagen S, Lee EA, Yang J, Hoatlin ME, Bielinsky AK, Hendrickson EA, Schärer O, Sobeck A. Functional crosstalk between the Fanconi anemia and ATRX/DAXX histone chaperone pathways promotes replication fork recovery. Human Molecular Genetics. PMID 31628488 DOI: 10.1093/hmg/ddz250  0.56
2019 Srinivasan G, Williamson EA, Kong K, Jaiswal AS, Huang G, Kim HS, Schärer O, Zhao W, Burma S, Sung P, Hromas R. MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers. Proceedings of the National Academy of Sciences of the United States of America. PMID 31395736 DOI: 10.1073/pnas.1903150116  0.52
2019 Cheon NY, Kim HS, Yeo JE, Schärer OD, Lee JY. Single-molecule visualization reveals the damage search mechanism for the human NER protein XPC-RAD23B. Nucleic Acids Research. PMID 31372632 DOI: 10.1093/nar/gkz629  0.56
2018 Mu H, Geacintov NE, Broyde S, Yeo JE, Schärer OD. Molecular basis for damage recognition and verification by XPC-RAD23B and TFIIH in nucleotide excision repair. Dna Repair. PMID 30174301 DOI: 10.1016/j.dnarep.2018.08.005  0.56
2017 Kato N, Kawasoe Y, Williams H, Coates E, Roy U, Shi Y, Beese LS, Schärer OD, Yan H, Gottesman ME, Takahashi TS, Gautier J. Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway. Cell Reports. 21: 1375-1385. PMID 29091773 DOI: 10.1016/j.celrep.2017.10.032  0.36
2017 Thompson EL, Yeo JE, Lee EA, Kan Y, Raghunandan M, Wiek C, Hanenberg H, Schärer OD, Hendrickson EA, Sobeck A. FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response. Nucleic Acids Research. PMID 29059323 DOI: 10.1093/nar/gkx847  0.56
2017 Castaño A, Roy U, Schärer OD. Preparation of Stable Nitrogen Mustard DNA Interstrand Cross-Link Analogs for Biochemical and Cell Biological Studies. Methods in Enzymology. 591: 415-431. PMID 28645378 DOI: 10.1016/bs.mie.2017.03.007  0.36
2017 Beagan K, Armstrong RL, Witsell A, Roy U, Renedo N, Baker AE, Scharer O, McVey M. Drosophila DNA polymerase theta utilizes both helicase-like and polymerase domains during microhomology-mediated end joining and interstrand crosslink repair. Plos Genetics. 13: e1006813. PMID 28542210 DOI: 10.1371/journal.pgen.1006813  0.36
2016 Pande P, Ji S, Mukherjee S, Schärer OD, Tretyakova NY, Basu AK. Mutagenicity of a model DNA-peptide cross-link in human cells: Roles of translesion synthesis DNA polymerases. Chemical Research in Toxicology. PMID 27951635 DOI: 10.1021/acs.chemrestox.6b00397  1
2016 Wickramaratne S, Ji S, Mukherjee S, Su Y, Pence MG, Lior-Hoffmann L, Fu I, Broyde S, Guengerich FP, Distefano M, Scharer OD, Sham YY, Tretyakova N. Bypass of DNA-Protein Cross-links Conjugated to the 7-Deazaguanine Position of DNA by Translesion Synthesis Polymerases. The Journal of Biological Chemistry. PMID 27621316 DOI: 10.1074/jbc.M116.745257  1
2016 Roy U, Schärer OD. Involvement of translesion synthesis DNA polymerases in DNA interstrand crosslink repair. Dna Repair. PMID 27311543 DOI: 10.1016/j.dnarep.2016.05.004  0.36
2016 Roy U, Mukherjee S, Sharma A, Frank EG, Schärer OD. The structure and duplex context of DNA interstrand crosslinks affects the activity of DNA polymerase η. Nucleic Acids Research. PMID 27257072 DOI: 10.1093/nar/gkw485  1
2015 Pizzolato J, Mukherjee S, Schärer OD, Jiricny J. FANCD2-associated Nuclease 1, but Not Exonuclease 1 or Flap Endonuclease 1, Is Able to Unhook DNA Interstrand Cross-links in Vitro. The Journal of Biological Chemistry. 290: 22602-11. PMID 26221031 DOI: 10.1074/jbc.M115.663666  1
2014 Mukherjee S, Guainazzi A, Schärer OD. Synthesis of structurally diverse major groove DNA interstrand crosslinks using three different aldehyde precursors. Nucleic Acids Research. 42: 7429-35. PMID 24782532 DOI: 10.1093/nar/gku328  1
2014 Hodskinson MR, Silhan J, Crossan GP, Garaycoechea JI, Mukherjee S, Johnson CM, Schärer OD, Patel KJ. Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair. Molecular Cell. 54: 472-84. PMID 24726326 DOI: 10.1016/j.molcel.2014.03.014  1
2013 Clauson C, Schärer OD, Niedernhofer L. Advances in understanding the complex mechanisms of DNA interstrand cross-link repair. Cold Spring Harbor Perspectives in Biology. 5: a012732. PMID 24086043 DOI: 10.1101/cshperspect.a012732  1
2013 Schärer OD. Nucleotide excision repair in eukaryotes. Cold Spring Harbor Perspectives in Biology. 5: a012609. PMID 24086042 DOI: 10.1101/cshperspect.a012609  1
2013 Wickramaratne S, Mukherjee S, Villalta PW, Schärer OD, Tretyakova NY. Synthesis of sequence-specific DNA-protein conjugates via a reductive amination strategy. Bioconjugate Chemistry. 24: 1496-506. PMID 23885807 DOI: 10.1021/bc400018u  1
2013 Bogliolo M, Schuster B, Stoepker C, Derkunt B, Su Y, Raams A, Trujillo JP, Minguillón J, Ramírez MJ, Pujol R, Casado JA, Baños R, Rio P, Knies K, Zúñiga S, et al. Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia. American Journal of Human Genetics. 92: 800-6. PMID 23623386 DOI: 10.1016/j.ajhg.2013.04.002  1
2013 Slean MM, Reddy K, Wu B, Nichol Edamura K, Kekis M, Nelissen FH, Aspers RL, Tessari M, Schärer OD, Wijmenga SS, Pearson CE. Interconverting conformations of slipped-DNA junctions formed by trinucleotide repeats affect repair outcome. Biochemistry. 52: 773-85. PMID 23339280 DOI: 10.1021/bi301369b  1
2012 Yeo JE, Khoo A, Fagbemi AF, Schärer OD. The efficiencies of damage recognition and excision correlate with duplex destabilization induced by acetylaminofluorene adducts in human nucleotide excision repair. Chemical Research in Toxicology. 25: 2462-8. PMID 23088760 DOI: 10.1021/tx3003033  1
2012 Knipscheer P, Räschle M, Schärer OD, Walter JC. Replication-coupled DNA interstrand cross-link repair in Xenopus egg extracts. Methods in Molecular Biology (Clifton, N.J.). 920: 221-43. PMID 22941607 DOI: 10.1007/978-1-61779-998-3_16  1
2012 Enoiu M, Ho TV, Long DT, Walter JC, Schärer OD. Construction of plasmids containing site-specific DNA interstrand cross-links for biochemical and cell biological studies. Methods in Molecular Biology (Clifton, N.J.). 920: 203-19. PMID 22941606 DOI: 10.1007/978-1-61779-998-3_15  1
2012 Enoiu M, Jiricny J, Schärer OD. Repair of cisplatin-induced DNA interstrand crosslinks by a replication-independent pathway involving transcription-coupled repair and translesion synthesis. Nucleic Acids Research. 40: 8953-64. PMID 22810206 DOI: 10.1093/nar/gks670  1
2012 Schärer OD. Alkyltransferase-like proteins: brokers dealing with alkylated DNA bases. Molecular Cell. 47: 3-4. PMID 22793691 DOI: 10.1016/j.molcel.2012.06.030  1
2012 Su Y, Orelli B, Madireddy A, Niedernhofer LJ, Schärer OD. Multiple DNA binding domains mediate the function of the ERCC1-XPF protein in nucleotide excision repair. The Journal of Biological Chemistry. 287: 21846-55. PMID 22547097 DOI: 10.1074/jbc.M111.337899  1
2012 Hentschel S, Alzeer J, Angelov T, Schärer OD, Luedtke NW. Synthesis of DNA interstrand cross-links using a photocaged nucleobase. Angewandte Chemie (International Ed. in English). 51: 3466-9. PMID 22344895 DOI: 10.1002/anie.201108018  1
2012 Sidorenko VS, Yeo JE, Bonala RR, Johnson F, Schärer OD, Grollman AP. Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts. Nucleic Acids Research. 40: 2494-505. PMID 22121226 DOI: 10.1093/nar/gkr1095  1
2011 Fu YV, Yardimci H, Long DT, Ho TV, Guainazzi A, Bermudez VP, Hurwitz J, van Oijen A, Schärer OD, Walter JC. Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase. Cell. 146: 931-41. PMID 21925316 DOI: 10.1016/j.cell.2011.07.045  1
2011 Ho TV, Guainazzi A, Derkunt SB, Enoiu M, Schärer OD. Structure-dependent bypass of DNA interstrand crosslinks by translesion synthesis polymerases. Nucleic Acids Research. 39: 7455-64. PMID 21666254 DOI: 10.1093/nar/gkr448  1
2011 Fagbemi AF, Orelli B, Schärer OD. Regulation of endonuclease activity in human nucleotide excision repair. Dna Repair. 10: 722-9. PMID 21592868 DOI: 10.1016/j.dnarep.2011.04.022  1
2011 Schärer OD. Multistep damage recognition, pathway coordination and connections to transcription, damage signaling, chromatin structure, cancer and aging: current perspectives on the nucleotide excision repair pathway. Dna Repair. 10: 667. PMID 21561812 DOI: 10.1016/j.dnarep.2011.04.017  1
2010 Guainazzi A, Campbell AJ, Angelov T, Simmerling C, Schärer OD. Synthesis and molecular modeling of a nitrogen mustard DNA interstrand crosslink. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 12100-3. PMID 20842675 DOI: 10.1002/chem.201002041  1
2010 Guainazzi A, Schärer OD. Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy. Cellular and Molecular Life Sciences : Cmls. 67: 3683-97. PMID 20730555 DOI: 10.1007/s00018-010-0492-6  1
2010 Ho TV, Schärer OD. Translesion DNA synthesis polymerases in DNA interstrand crosslink repair. Environmental and Molecular Mutagenesis. 51: 552-66. PMID 20658647 DOI: 10.1002/em.20573  1
2010 Ahmad A, Enzlin JH, Bhagwat NR, Wijgers N, Raams A, Appledoorn E, Theil AF, J Hoeijmakers JH, Vermeulen W, J Jaspers NG, Schärer OD, Niedernhofer LJ. Mislocalization of XPF-ERCC1 nuclease contributes to reduced DNA repair in XP-F patients. Plos Genetics. 6: e1000871. PMID 20221251 DOI: 10.1371/journal.pgen.1000871  1
2010 Orelli B, McClendon TB, Tsodikov OV, Ellenberger T, Niedernhofer LJ, Schärer OD. The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways. The Journal of Biological Chemistry. 285: 3705-12. PMID 19940136 DOI: 10.1074/jbc.M109.067538  1
2010 Schärer OD, Campbell AJ. Mechanisms of Base Excision Repair and Nucleotide Excision Repair The Chemical Biology of Dna Damage. 239-260. DOI: 10.1002/9783527630110.ch11  1
2009 Knipscheer P, Räschle M, Smogorzewska A, Enoiu M, Ho TV, Schärer OD, Elledge SJ, Walter JC. The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair. Science (New York, N.Y.). 326: 1698-701. PMID 19965384 DOI: 10.1126/science.1182372  1
2009 Staresincic L, Fagbemi AF, Enzlin JH, Gourdin AM, Wijgers N, Dunand-Sauthier I, Giglia-Mari G, Clarkson SG, Vermeulen W, Schärer OD. Coordination of dual incision and repair synthesis in human nucleotide excision repair. The Embo Journal. 28: 1111-20. PMID 19279666 DOI: 10.1038/emboj.2009.49  1
2009 Schärer OD, Campbell AJ. Wedging out DNA damage. Nature Structural & Molecular Biology. 16: 102-4. PMID 19190661 DOI: 10.1038/nsmb0209-102  1
2009 Angelov T, Guainazzi A, Schärer OD. Generation of DNA interstrand cross-links by post-synthetic reductive amination. Organic Letters. 11: 661-4. PMID 19132933 DOI: 10.1021/ol802719a  1
2009 Schärer OD. Structure-specific endonucleases in DNA repair Chimia. 63: 753-757. DOI: 10.2533/chimia.2009.753  1
2009 Räschle M, Knipscheer P, Enoiu M, Angelov T, Sun J, Griffith JD, Ellenberger TE, Schärer OD, Walter JC. Mechanism of Replication-Coupled DNA Interstrand Crosslink Repair (DOI:10.1016/j.cell.2008.08.030) Cell. 137: 972. DOI: 10.1016/j.cell.2009.05.009  1
2008 Schärer OD. XPG: its products and biological roles. Advances in Experimental Medicine and Biology. 637: 83-92. PMID 19181113 DOI: 10.1007/978-0-387-09599-8_9  1
2008 Räschle M, Knipscheer P, Knipsheer P, Enoiu M, Angelov T, Sun J, Griffith JD, Ellenberger TE, Schärer OD, Walter JC. Mechanism of replication-coupled DNA interstrand crosslink repair. Cell. 134: 969-80. PMID 18805090 DOI: 10.1016/j.cell.2008.08.030  1
2008 Maltseva EA, Rechkunova NI, Petruseva IO, Vermeulen W, Schärer OD, Lavrik OI. Crosslinking of nucleotide excision repair proteins with DNA containing photoreactive damages. Bioorganic Chemistry. 36: 77-84. PMID 18191172 DOI: 10.1016/j.bioorg.2007.11.004  1
2008 Schärer OD. Hot topics in DNA repair: the molecular basis for different disease states caused by mutations in TFIIH and XPG. Dna Repair. 7: 339-44. PMID 18077223 DOI: 10.1016/j.dnarep.2007.10.007  1
2008 Schärer OD. A molecular basis for damage recognition in eukaryotic nucleotide excision repair. Chembiochem : a European Journal of Chemical Biology. 9: 21-3. PMID 18033706 DOI: 10.1002/cbic.200700619  1
2007 Schärer OD. Achieving broad substrate specificity in damage recognition by binding accessible nondamaged DNA. Molecular Cell. 28: 184-6. PMID 17964258 DOI: 10.1016/j.molcel.2007.10.006  1
2007 Tsodikov OV, Ivanov D, Orelli B, Staresincic L, Shoshani I, Oberman R, Schärer OD, Wagner G, Ellenberger T. Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA. The Embo Journal. 26: 4768-76. PMID 17948053 DOI: 10.1038/sj.emboj.7601894  1
2007 Hohl M, Dunand-Sauthier I, Staresincic L, Jaquier-Gubler P, Thorel F, Modesti M, Clarkson SG, Schärer OD. Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity. Nucleic Acids Research. 35: 3053-63. PMID 17452369 DOI: 10.1093/nar/gkm092  1
2007 Maltseva EA, Rechkunova NI, Gillet LC, Petruseva IO, Schärer OD, Lavrik OI. Crosslinking of the NER damage recognition proteins XPC-HR23B, XPA and RPA to photoreactive probes that mimic DNA damages. Biochimica Et Biophysica Acta. 1770: 781-9. PMID 17320292 DOI: 10.1016/j.bbagen.2007.01.007  1
2006 Alzeer J, Schärer OD. A modified thymine for the synthesis of site-specific thymine-guanine DNA interstrand crosslinks. Nucleic Acids Research. 34: 4458-66. PMID 16945959 DOI: 10.1093/nar/gkl587  1
2006 Gillet LC, Schärer OD. Molecular mechanisms of mammalian global genome nucleotide excision repair. Chemical Reviews. 106: 253-76. PMID 16464005 DOI: 10.1021/cr040483f  1
2005 Tsodikov OV, Enzlin JH, Schärer OD, Ellenberger T. Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1. Proceedings of the National Academy of Sciences of the United States of America. 102: 11236-41. PMID 16076955 DOI: 10.1073/pnas.0504341102  1
2005 Gillet LC, Alzeer J, Schärer OD. Site-specific incorporation of N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (dG-AAF) into oligonucleotides using modified 'ultra-mild' DNA synthesis. Nucleic Acids Research. 33: 1961-9. PMID 15814813 DOI: 10.1093/nar/gki335  1
2005 Schärer O, Schultz C. Closing the gap between chemistry and biology Chembiochem. 6: 3-5. PMID 15637665 DOI: 10.1002/cbic.200400405  1
2005 Schärer OD. DNA interstrand crosslinks: natural and drug-induced DNA adducts that induce unique cellular responses. Chembiochem : a European Journal of Chemical Biology. 6: 27-32. PMID 15637664 DOI: 10.1002/cbic.200400287  1
2005 Dunand-Sauthier I, Hohl M, Thorel F, Jaquier-Gubler P, Clarkson SG, Schärer OD. The spacer region of XPG mediates recruitment to nucleotide excision repair complexes and determines substrate specificity. The Journal of Biological Chemistry. 280: 7030-7. PMID 15590680 DOI: 10.1074/jbc.M412228200  1
2004 Tapias A, Auriol J, Forget D, Enzlin JH, Schärer OD, Coin F, Coulombe B, Egly JM. Ordered conformational changes in damaged DNA induced by nucleotide excision repair factors. The Journal of Biological Chemistry. 279: 19074-83. PMID 14981083 DOI: 10.1074/jbc.M312611200  1
2003 Schärer OD. Chemistry and biology of DNA repair. Angewandte Chemie (International Ed. in English). 42: 2946-74. PMID 12851945 DOI: 10.1002/anie.200200523  1
2003 Hohl M, Thorel F, Clarkson SG, Schärer OD. Structural determinants for substrate binding and catalysis by the structure-specific endonuclease XPG. The Journal of Biological Chemistry. 278: 19500-8. PMID 12644470 DOI: 10.1074/jbc.M213155200  1
2002 Gillet LC, Schärer OD. Preparation of C8-amine and acetylamine adducts of 2'-deoxyguanosine suitably protected for DNA synthesis. Organic Letters. 4: 4205-8. PMID 12443059 DOI: 10.1021/ol026474f  1
2002 Godthelp BC, Wiegant WW, van Duijn-Goedhart A, Schärer OD, van Buul PP, Kanaar R, Zdzienicka MZ. Mammalian Rad51C contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability. Nucleic Acids Research. 30: 2172-82. PMID 12000837  1
2002 Enzlin JH, Schärer OD. The active site of the DNA repair endonuclease XPF-ERCC1 forms a highly conserved nuclease motif. The Embo Journal. 21: 2045-53. PMID 11953324 DOI: 10.1093/emboj/21.8.2045  1
2001 Schärer OD, Jiricny J. Recent progress in the biology, chemistry and structural biology of DNA glycosylases Bioessays. 23: 270-281. PMID 11223884 DOI: 10.1002/1521-1878(200103)23:3<270::AID-BIES1037>3.0.CO;2-J  1
2001 Schärer OD. Chemical biology of mammalian DNA repair Chimia. 55: 340-344.  1
1999 Barrett TE, Schärer OD, Savva R, Brown T, Jiricny J, Verdine GL, Pearl LH. Crystal structure of a thwarted mismatch glycosylase DNA repair complex. The Embo Journal. 18: 6599-609. PMID 10581234 DOI: 10.1093/emboj/18.23.6599  1
1999 Bennink ML, Schärer OD, Kanaar R, Sakata-Sogawa K, Schins JM, Kanger JS, De Grooth BG, Greve J. Single-molecule manipulation of double-stranded DNA using optical tweezers: Interaction studies of DNA with RecA and YOYO-1 Cytometry. 36: 200-208. PMID 10404969 DOI: 10.1002/(SICI)1097-0320(19990701)36:3<200::AID-CYTO9>3.0.CO;2-T  1
1998 Lau AY, Schärer OD, Samson L, Verdine GL, Ellenberger T. Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision. Cell. 95: 249-58. PMID 9790531 DOI: 10.1016/S0092-8674(00)81755-9  1
1998 Erzberger JP, Barsky D, Schärer OD, Colvin ME, Wilson DM. Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases. Nucleic Acids Research. 26: 2771-8. PMID 9592167 DOI: 10.1093/nar/26.11.2771  1
1998 Schärer OD, Nash HM, Jiricny J, Laval J, Verdine GL. Specific binding of a designed pyrrolidine abasic site analog to multiple DNA glycosylases. The Journal of Biological Chemistry. 273: 8592-7. PMID 9535832 DOI: 10.1074/jbc.273.15.8592  1
1997 Schärer OD, Deng L, Verdine GL. Chemical approaches toward understanding base excision DNA repair. Current Opinion in Chemical Biology. 1: 526-31. PMID 9667887  1
1997 McCullough AK, Dodson ML, Schärer OD, Lloyd RS. The role of base flipping in damage recognition and catalysis by T4 endonuclease V. The Journal of Biological Chemistry. 272: 27210-7. PMID 9341165 DOI: 10.1074/jbc.272.43.27210  1
1997 Schärer OD, Kawate T, Gallinari P, Jiricny J, Verdine GL. Investigation of the mechanisms of DNA binding of the human G/T glycosylase using designed inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 94: 4878-83. PMID 9144158 DOI: 10.1073/pnas.94.10.4878  1
1997 Deng L, Scharer OD, Verdine GL. Unusually strong binding of a designed transition-state analog to a base-excision DNA repair protein Journal of the American Chemical Society. 119: 7865-7866. DOI: 10.1021/ja970828u  1
1996 McCullough AK, Schärer O, Verdine GL, Lloyd RS. Structural determinants for specific recognition by T4 endonuclease V. The Journal of Biological Chemistry. 271: 32147-52. PMID 8943268 DOI: 10.1074/jbc.271.50.32147  1
1996 Nash HM, Bruner SD, Schärer OD, Kawate T, Addona TA, Spooner E, Lane WS, Verdine GL. Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily. Current Biology : Cb. 6: 968-80. PMID 8805338 DOI: 10.1016/S0960-9822(02)00641-3  1
1996 Labahn J, Schärer OD, Long A, Ezaz-Nikpay K, Verdine GL, Ellenberger TE. Structural basis for the excision repair of alkylation-damaged DNA. Cell. 86: 321-9. PMID 8706136 DOI: 10.1016/S0092-8674(00)80103-8  1
1995 Schärer OD, Ortholand JY, Ganesan A, Ezaz-Nikpay K, Verdine GL. Specific binding of the DNA repair enzyme AlkA to a pyrrolidine-based inhibitor Journal of the American Chemical Society. 117: 6623-6624. DOI: 10.1021/ja00129a039  1
1995 Schärer OD, Verdine GL. A designed inhibitor of base-excision DNA repair Journal of the American Chemical Society. 117: 10781-10782.  1
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