| Year |
Citation |
Score |
| 2016 |
Knudson SE, Cummings JE, Bommineni GR, Pan P, Tonge PJ, Slayden RA. Formulation studies of InhA inhibitors and combination therapy to improve efficacy against Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 101: 8-14. PMID 27865404 DOI: 10.1016/J.Tube.2016.07.016 |
0.582 |
|
| 2016 |
Neckles CM, Pschibul A, Lai CE, Hirschbeck M, Kuper J, Davoodi S, Zou J, Liu N, Pan P, Shah S, Daryaee F, Bommineni GR, Lai C, Simmerling C, Kisker C, et al. Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase FabV. Biochemistry. PMID 27136302 DOI: 10.1021/Acs.Biochem.5B01301 |
0.716 |
|
| 2015 |
Pan P, Tian S, Sun H, Kong X, Zhou W, Li D, Li Y, Hou T. Identification and Preliminary SAR Analysis of Novel Type-I Inhibitors of TIE-2 via Structure-Based Virtual Screening and Biological Evaluation in in vitro Models. Journal of Chemical Information and Modeling. PMID 26618892 DOI: 10.1021/Acs.Jcim.5B00576 |
0.379 |
|
| 2015 |
Shen M, Tian S, Pan P, Sun H, Li D, Li Y, Zhou H, Li C, Lee SM, Hou T. Discovery of Novel ROCK1 Inhibitors via Integrated Virtual Screening Strategy and Bioassays. Scientific Reports. 5: 16749. PMID 26568382 DOI: 10.1038/Srep16749 |
0.333 |
|
| 2015 |
La Regina G, Coluccia A, Famiglini V, Pelliccia S, Monti L, Vullo D, Nuti E, Alterio V, De Simone G, Monti SM, Pan P, Parkkila S, Supuran CT, Rossello A, Silvestri R. Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors. Journal of Medicinal Chemistry. 58: 8564-72. PMID 26497049 DOI: 10.1021/acs.jmedchem.5b01144 |
0.36 |
|
| 2015 |
Wang H, Liu L, Lu Y, Pan P, Hooker JM, Fowler JS, Tonge PJ. Radiolabelling and positron emission tomography of PT70, a time-dependent inhibitor of InhA, the Mycobacterium tuberculosis enoyl-ACP reductase. Bioorganic & Medicinal Chemistry Letters. PMID 26227776 DOI: 10.1016/J.Bmcl.2015.07.019 |
0.575 |
|
| 2014 |
Schiebel J, Chang A, Shah S, Lu Y, Liu L, Pan P, Hirschbeck MW, Tareilus M, Eltschkner S, Yu W, Cummings JE, Knudson SE, Bommineni GR, Walker SG, Slayden RA, et al. Rational design of broad spectrum antibacterial activity based on a clinically relevant enoyl-acyl carrier protein (ACP) reductase inhibitor. The Journal of Biological Chemistry. 289: 15987-6005. PMID 24739388 DOI: 10.1074/Jbc.M113.532804 |
0.652 |
|
| 2014 |
Pan P, Knudson SE, Bommineni GR, Li HJ, Lai CT, Liu N, Garcia-Diaz M, Simmerling C, Patil SS, Slayden RA, Tonge PJ. Time-dependent diaryl ether inhibitors of InhA: structure-activity relationship studies of enzyme inhibition, antibacterial activity, and in vivo efficacy. Chemmedchem. 9: 776-91. PMID 24616444 DOI: 10.1002/Cmdc.201300429 |
0.735 |
|
| 2014 |
Li HJ, Lai CT, Pan P, Yu W, Liu N, Bommineni GR, Garcia-Diaz M, Simmerling C, Tonge PJ. A structural and energetic model for the slow-onset inhibition of the Mycobacterium tuberculosis enoyl-ACP reductase InhA. Acs Chemical Biology. 9: 986-93. PMID 24527857 DOI: 10.1021/Cb400896G |
0.721 |
|
| 2014 |
Pan P, Knudson SE, Bommineni GR, Li H, Lai C, Liu N, Garcia-Diaz M, Simmerling C, Patil SS, Slayden RA, Tonge PJ. Cover Picture: Time-Dependent Diaryl Ether Inhibitors of InhA: Structure-Activity Relationship Studies of Enzyme Inhibition, Antibacterial Activity, and in vivo Efficacy (ChemMedChem 4/2014) Chemmedchem. 9: 673-673. DOI: 10.1002/Cmdc.201490010 |
0.716 |
|
| 2013 |
Chang A, Schiebel J, Yu W, Bommineni GR, Pan P, Baxter MV, Khanna A, Sotriffer CA, Kisker C, Tonge PJ. Rational optimization of drug-target residence time: insights from inhibitor binding to the Staphylococcus aureus FabI enzyme-product complex. Biochemistry. 52: 4217-28. PMID 23697754 DOI: 10.1021/Bi400413C |
0.671 |
|
| 2012 |
Pan P, Tonge PJ. Targeting InhA, the FASII enoyl-ACP reductase: SAR studies on novel inhibitor scaffolds. Current Topics in Medicinal Chemistry. 12: 672-93. PMID 22283812 DOI: 10.2174/156802612799984535 |
0.679 |
|
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