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Norbert O. Reich - Publications

Chemistry University of California, Santa Barbara, Santa Barbara, CA, United States 
Materials Chemistry, Biochemistry & Biophysics, Biomedical Sciences, Biology-Inspired Chemistry & Physics, Deivces, Assembly & Nanochemistry, Structural Chemistry, Spectroscopy & Advanced Analysis

149 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Huang S, Stillson NJ, Sandoval JE, Yung C, Reich NO. A Novel Class of Selective Non-Nucleoside Inhibitors of Human DNA Methyltransferase 3A. Bioorganic & Medicinal Chemistry Letters. 127908. PMID 33705897 DOI: 10.1016/j.bmcl.2021.127908  0.404
2020 Sandoval JE, Reich NO. p53 and TDG are dominant in regulating the activity of the human de novo DNA methyltransferase DNMT3A on nucleosomes. The Journal of Biological Chemistry. PMID 33172892 DOI: 10.1074/jbc.RA120.016125  0.353
2020 Konttinen O, Carmody J, Pathuri S, Anderson K, Zhou X, Reich N. Cell cycle regulated DNA methyltransferase: fluorescent tracking of a DNA strand-separation mechanism and identification of the responsible protein motif. Nucleic Acids Research. PMID 33053173 DOI: 10.1093/nar/gkaa844  0.501
2020 Konttinen OR, Reich NO, Carmody J, Kurnik M. Investigation of the DNA strand separation step by DNA methyltransferase Caulobacter Crescentus The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00658  0.539
2019 Sandoval JE, Reich NO. The R882H substitution in the human de novo DNA methyltransferase DNMT3A disrupts allosteric regulation by the tumor supressor p53. The Journal of Biological Chemistry. PMID 31640986 DOI: 10.1074/Jbc.Ra119.010827  0.384
2019 Horton JR, Woodcock CB, Opot SB, Reich NO, Zhang X, Cheng X. The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site. Nature Communications. 10: 4600. PMID 31601797 DOI: 10.1038/S41467-019-12498-7  0.563
2019 Barel I, Reich NO, Brown FLH. Integrated rate laws for processive and distributive enzymatic turnover. The Journal of Chemical Physics. 150: 244120. PMID 31255081 DOI: 10.1063/1.5097576  0.452
2019 Sandoval JE, Huang YH, Muise A, Goodell MA, Reich NO. Mutations in the DNMT3A DNA methyltransferase in AML patients cause both loss and gain of function and differential regulation by protein partners. The Journal of Biological Chemistry. PMID 30705090 DOI: 10.1074/Jbc.Ra118.006795  0.476
2018 Reich NO, Dang E, Kurnik M, Pathuri S, Woodcock CB. The highly specific, cell cycle-regulated methyltransferase from Caulobacter crescentus relies on a novel DNA recognition mechanism. The Journal of Biological Chemistry. PMID 30323065 DOI: 10.1074/Jbc.Ra118.005212  0.541
2018 Morales DP, Morgan EN, McAdams M, Chron AB, Shin JE, Zasadzinski JA, Reich NO. Light-Triggered Genome Editing: Cre Recombinase Mediated Gene Editing with Near-Infrared Light. Small (Weinheim An Der Bergstrasse, Germany). e1800543. PMID 29968382 DOI: 10.1002/Smll.201800543  0.331
2017 Barel I, Naughton BS, Reich NO, Brown FLH. Specificity versus Processivity in the Sequential Methylation of DNA: A Study of DNA Adenine Methyltransferase. The Journal of Physical Chemistry. B. PMID 29258307 DOI: 10.1021/Acs.Jpcb.7B10349  0.568
2017 Woodcock CB, Yakubov AB, Reich NO. Caulobacter crescentus cell cycle regulated DNA methyltransferase uses a novel mechanism for substrate recognition. Biochemistry. PMID 28661661 DOI: 10.1021/Acs.Biochem.7B00378  0.583
2017 Huang X, Lai Y, Braun GB, Reich NO. RNA Delivery: Modularized Gold Nanocarriers for TAT-Mediated Delivery of siRNA (Small 8/2017) Small. 13. DOI: 10.1002/Smll.201770044  0.601
2016 Naughton BS, Reich NO. Mechanisms of Protein Translocation on DNA Are Differentially Responsive to Water Activity. Biochemistry. 55: 6957-6960. PMID 27992993 DOI: 10.1021/Acs.Biochem.6B00872  0.448
2016 Huang X, Lai Y, Braun GB, Reich NO. Modularized Gold Nanocarriers for TAT-Mediated Delivery of siRNA. Small (Weinheim An Der Bergstrasse, Germany). PMID 27860237 DOI: 10.1002/Smll.201602473  0.635
2016 Woodcock CB, Ulashchik EA, Poopeiko NE, Shmanai V, Reich NO, Shchepinov MS. Rational manipulation of DNA methylation using isotopically reinforced cytosine. Chembiochem : a European Journal of Chemical Biology. PMID 27595234 DOI: 10.1002/Cbic.201600393  0.527
2015 Barel I, Reich NO, Brown FL. Extracting enzyme processivity from kinetic assays. The Journal of Chemical Physics. 143: 224115. PMID 26671366 DOI: 10.1063/1.4937155  0.433
2015 Huang X, Hu Q, Braun GB, Pallaoro A, Morales DP, Zasadzinski J, Clegg DO, Reich NO. Light-activated RNA interference in human embryonic stem cells. Biomaterials. 63: 70-9. PMID 26086448 DOI: 10.1016/J.Biomaterials.2015.06.006  0.623
2015 Pollak AJ, Reich NO. DNA adenine methyltransferase facilitated diffusion is enhanced by protein-DNA "roadblock" complexes that induce DNA looping. Biochemistry. 54: 2181-92. PMID 25785689 DOI: 10.1021/Bi501344R  0.854
2015 Holz-Schietinger C, Reich NO. De novo DNA methyltransferase DNMT3A: Regulation of oligomeric state and mechanism of action in response to pH changes. Biochimica Et Biophysica Acta. 1850: 1131-9. PMID 25681155 DOI: 10.1016/J.Bbagen.2015.02.003  0.783
2015 Morales DP, Braun GB, Pallaoro A, Chen R, Huang X, Zasadzinski JA, Reich NO. Targeted intracellular delivery of proteins with spatial and temporal control. Molecular Pharmaceutics. 12: 600-9. PMID 25490248 DOI: 10.1021/Mp500675P  0.61
2014 Pollak AJ, Chin AT, Reich NO. Distinct facilitated diffusion mechanisms by E. coli Type II restriction endonucleases. Biochemistry. 53: 7028-37. PMID 25350874 DOI: 10.1021/Bi501110R  0.85
2014 Pollak AJ, Chin AT, Brown FL, Reich NO. DNA looping provides for "intersegmental hopping" by proteins: a mechanism for long-range site localization. Journal of Molecular Biology. 426: 3539-52. PMID 25134757 DOI: 10.1016/J.Jmb.2014.08.002  0.859
2014 Braun GB, Friman T, Pang HB, Pallaoro A, Hurtado de Mendoza T, Willmore AM, Kotamraju VR, Mann AP, She ZG, Sugahara KN, Reich NO, Teesalu T, Ruoslahti E. Etchable plasmonic nanoparticle probes to image and quantify cellular internalization. Nature Materials. 13: 904-11. PMID 24907927 DOI: 10.1038/Nmat3982  0.624
2014 Huang X, Pallaoro A, Braun GB, Morales DP, Ogunyankin MO, Zasadzinski J, Reich NO. Modular plasmonic nanocarriers for efficient and targeted delivery of cancer-therapeutic siRNA. Nano Letters. 14: 2046-51. PMID 24597503 DOI: 10.1021/Nl500214E  0.618
2014 Koyfman AY, Reich NO. Construction and Computation with Nucleic Acids on the Cell Surface Micro-and Nanoengineering of the Cell Surface. 157-173. DOI: 10.1016/B978-1-4557-3146-6.00008-8  0.723
2013 Matje DM, Krivacic CT, Dahlquist FW, Reich NO. Distal structural elements coordinate a conserved base flipping network. Biochemistry. 52: 1669-76. PMID 23409802 DOI: 10.1021/Bi301284F  0.844
2013 Matje DM, Zhou H, Smith DA, Neely RK, Dryden DT, Jones AC, Dahlquist FW, Reich NO. Enzyme-promoted base flipping controls DNA methylation fidelity. Biochemistry. 52: 1677-85. PMID 23409782 DOI: 10.1021/Bi3012912  0.846
2013 Bonham AJ, Wenta N, Osslund LM, Prussin AJ, Vinkemeier U, Reich NO. STAT1:DNA sequence-dependent binding modulation by phosphorylation, protein:protein interactions and small-molecule inhibition. Nucleic Acids Research. 41: 754-63. PMID 23180800 DOI: 10.1093/Nar/Gks1085  0.715
2012 Holz-Schietinger C, Reich NO. RNA modulation of the human DNA methyltransferase 3A. Nucleic Acids Research. 40: 8550-7. PMID 22730298 DOI: 10.1093/Nar/Gks537  0.81
2012 Matje DM, Reich NO. Molecular drivers of base flipping during sequence-specific DNA methylation. Chembiochem : a European Journal of Chemical Biology. 13: 1574-7. PMID 22730226 DOI: 10.1002/Cbic.201200104  0.825
2012 Holz-Schietinger C, Matje DM, Reich NO. Mutations in DNA methyltransferase (DNMT3A) observed in acute myeloid leukemia patients disrupt processive methylation. The Journal of Biological Chemistry. 287: 30941-51. PMID 22722925 DOI: 10.1074/Jbc.M112.366625  0.799
2012 Pollak AJ, Reich NO. Proximal recognition sites facilitate intrasite hopping by DNA adenine methyltransferase: mechanistic exploration of epigenetic gene regulation. The Journal of Biological Chemistry. 287: 22873-81. PMID 22570478 DOI: 10.1074/Jbc.M111.332502  0.847
2012 Laurence TA, Braun GB, Reich NO, Moskovits M. Robust SERS enhancement factor statistics using rotational correlation spectroscopy. Nano Letters. 12: 2912-7. PMID 22551121 DOI: 10.1021/Nl3005447  0.622
2011 Holz-Schietinger C, Matje DM, Harrison MF, Reich NO. Oligomerization of DNMT3A controls the mechanism of de novo DNA methylation. The Journal of Biological Chemistry. 286: 41479-88. PMID 21979949 DOI: 10.1074/Jbc.M111.284687  0.821
2011 Vallée-Bélisle A, Bonham AJ, Reich NO, Ricci F, Plaxco KW. Transcription factor beacons for the quantitative detection of DNA binding activity. Journal of the American Chemical Society. 133: 13836-9. PMID 21815647 DOI: 10.1021/Ja204775K  0.784
2011 Menezes S, Gaston KW, Krivos KL, Apolinario EE, Reich NO, Sowers KR, Limbach PA, Perona JJ. Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14. Nucleic Acids Research. 39: 7641-55. PMID 21693558 DOI: 10.1093/Nar/Gkr475  0.326
2011 Matje DM, Coughlin DF, Connolly BA, Dahlquist FW, Reich NO. Determinants of precatalytic conformational transitions in the DNA cytosine methyltransferase M.HhaI. Biochemistry. 50: 1465-73. PMID 21229971 DOI: 10.1021/Bi101446G  0.836
2010 Holz-Schietinger C, Reich NO. The inherent processivity of the human de novo methyltransferase 3A (DNMT3A) is enhanced by DNMT3L. The Journal of Biological Chemistry. 285: 29091-100. PMID 20630873 DOI: 10.1074/Jbc.M110.142513  0.847
2010 Purdy MM, Holz-Schietinger C, Reich NO. Identification of a second DNA binding site in human DNA methyltransferase 3A by substrate inhibition and domain deletion. Archives of Biochemistry and Biophysics. 498: 13-22. PMID 20227382 DOI: 10.1016/J.Abb.2010.03.007  0.844
2010 Pallaoro A, Braun GB, Reich NO, Moskovits M. Mapping local pH in live cells using encapsulated fluorescent SERS nanotags. Small (Weinheim An Der Bergstrasse, Germany). 6: 618-22. PMID 20183812 DOI: 10.1002/Smll.200901893  0.624
2010 Zhang F, Braun GB, Shi Y, Zhang Y, Sun X, Reich NO, Zhao D, Stucky G. Fabrication of Ag@SiO(2)@Y(2)O(3):Er nanostructures for bioimaging: tuning of the upconversion fluorescence with silver nanoparticles. Journal of the American Chemical Society. 132: 2850-1. PMID 20158187 DOI: 10.1021/Ja909108X  0.609
2010 Lee SJ, Piorek B, Braun G, Deng XG, Meinhart C, Reich N, Tombler T, Moskovits M. Transforming SERS into a dependable platform for ultra-sensitive molecular sensing Aip Conference Proceedings. 1267: 8-9. DOI: 10.1063/1.3482878  0.559
2010 Peterson SN, Reich NO. LRP: A nucleoid-associated protein with gene regulatory functions Bacterial Chromatin. 353-364. DOI: 10.1007/978-90-481-3473-1-15  0.592
2010 Pallaoro A, Braun GB, Reich NO, Moskovits M. Sensing nanoparticles: Small 5/2010 Small. 6: NA-NA. DOI: 10.1002/Smll.201090012  0.608
2009 Koyfman AY, Braun GB, Reich NO. Cell-targeted self-assembled DNA nanostructures. Journal of the American Chemical Society. 131: 14237-9. PMID 19754205 DOI: 10.1021/Ja9015638  0.818
2009 Coffin SR, Reich NO. Escherichia coli DNA adenine methyltransferase: intrasite processivity and substrate-induced dimerization and activation. Biochemistry. 48: 7399-410. PMID 19580332 DOI: 10.1021/Bi9008006  0.858
2009 Zhou H, Purdy MM, Dahlquist FW, Reich NO. The recognition pathway for the DNA cytosine methyltransferase M.HhaI. Biochemistry. 48: 7807-16. PMID 19580326 DOI: 10.1021/Bi900502G  0.58
2009 Braun GB, Pallaoro A, Wu G, Missirlis D, Zasadzinski JA, Tirrell M, Reich NO. Laser-Activated Gene Silencing via Gold Nanoshell-siRNA Conjugates. Acs Nano. 3: 2007-15. PMID 19527019 DOI: 10.1021/Nn900469Q  0.605
2009 Estabrook RA, Nguyen TT, Fera N, Reich NO. Coupling sequence-specific recognition to DNA modification. The Journal of Biological Chemistry. 284: 22690-6. PMID 19497854 DOI: 10.1074/Jbc.M109.015966  0.841
2009 Bonham AJ, Neumann T, Tirrell M, Reich NO. Tracking transcription factor complexes on DNA using total internal reflectance fluorescence protein binding microarrays. Nucleic Acids Research. 37: e94. PMID 19487241 DOI: 10.1093/Nar/Gkp424  0.753
2009 Coffin SR, Reich NO. Escherichia coli DNA adenine methyltransferase: the structural basis of processive catalysis and indirect read-out. The Journal of Biological Chemistry. 284: 18390-400. PMID 19419959 DOI: 10.1074/Jbc.M109.005876  0.848
2009 Ricci F, Bonham AJ, Mason AC, Reich NO, Plaxco KW. Reagentless, electrochemical approach for the specific detection of double- and single-stranded DNA binding proteins. Analytical Chemistry. 81: 1608-14. PMID 19199570 DOI: 10.1021/Ac802365X  0.788
2009 Koyfman AY, Magonov SN, Reich NO. Self-assembly of DNA arrays into multilayer stacks. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 1091-6. PMID 19177652 DOI: 10.1021/La801306J  0.788
2009 Laurence TA, Braun G, Talley C, Schwartzberg A, Moskovits M, Reich N, Huser T. Rapid, solution-based characterization of optimized SERS nanoparticle substrates. Journal of the American Chemical Society. 131: 162-9. PMID 19063599 DOI: 10.1021/Ja806236K  0.618
2009 Moskovits M, Braun GB, Lee SJ, Laurence T, Fera N, Fabris L, Bazan GC, Reich NO. Generalized approach to SERS-active nanomaterials via controlled nanoparticle linking, polymer encapsulation, and small-molecule infusion Journal of Physical Chemistry C. 113: 13622-13629. DOI: 10.1021/Jp903399P  0.621
2008 Peterson SN, Reich NO. Competitive Lrp and Dam assembly at the pap regulatory region: implications for mechanisms of epigenetic regulation. Journal of Molecular Biology. 383: 92-105. PMID 18706913 DOI: 10.1016/J.Jmb.2008.07.086  0.718
2008 Youngblood B, Reich NO. The early expressed HIV-1 genes regulate DNMT1 expression. Epigenetics. 3: 149-56. PMID 18567946 DOI: 10.4161/Epi.3.3.6372  0.326
2008 Coffin SR, Reich NO. Modulation of Escherichia coli DNA methyltransferase activity by biologically derived GATC-flanking sequences. The Journal of Biological Chemistry. 283: 20106-16. PMID 18502761 DOI: 10.1074/Jbc.M802502200  0.847
2008 Youngblood B, Bonnist E, Dryden DT, Jones AC, Reich NO. Differential stabilization of reaction intermediates: specificity checkpoints for M.EcoRI revealed by transient fluorescence and fluorescence lifetime studies. Nucleic Acids Research. 36: 2917-25. PMID 18385156 DOI: 10.1093/Nar/Gkn131  0.534
2008 Braun G, Diechtierow M, Wilkinson S, Schmidt F, Hüben M, Weinhold E, Reich NO. Enzyme-directed positioning of nanoparticles on large DNA templates. Bioconjugate Chemistry. 19: 476-9. PMID 18088085 DOI: 10.1021/Bc700275H  0.699
2008 Wilkinson S, Diechtierow M, Estabrook RA, Schmidt F, Hüben M, Weinhold E, Reich NO. Molecular scale architecture: Engineered three- and four-way junctions Bioconjugate Chemistry. 19: 470-475. PMID 18069780 DOI: 10.1021/Bc700270K  0.842
2007 Bonham AJ, Braun G, Pavel I, Moskovits M, Reich NO. Detection of sequence-specific protein-DNA interactions via surface enhanced resonance Raman scattering. Journal of the American Chemical Society. 129: 14572-3. PMID 17985912 DOI: 10.1021/Ja0767837  0.832
2007 Kim JH, Estabrook RA, Braun G, Lee BR, Reich NO. Specific and sensitive detection of nucleic acids and RNases using gold nanoparticle-RNA-fluorescent dye conjugates. Chemical Communications (Cambridge, England). 4342-4. PMID 17957280 DOI: 10.1039/B710306A  0.787
2007 Shieh FK, Reich NO. AdoMet-dependent methyl-transfer: Glu119 is essential for DNA C5-cytosine methyltransferase M.HhaI. Journal of Molecular Biology. 373: 1157-68. PMID 17897676 DOI: 10.1016/J.Jmb.2007.08.009  0.752
2007 Youngblood B, Shieh FK, Buller F, Bullock T, Reich NO. S-adenosyl-L-methionine-dependent methyl transfer: observable precatalytic intermediates during DNA cytosine methylation. Biochemistry. 46: 8766-75. PMID 17616174 DOI: 10.1021/Bi7005948  0.715
2007 Braun G, Pavel I, Morrill AR, Seferos DS, Bazan GC, Reich NO, Moskovits M. Chemically patterned microspheres for controlled nanoparticle assembly in the construction of SERS hot spots. Journal of the American Chemical Society. 129: 7760-1. PMID 17539645 DOI: 10.1021/Ja072533E  0.637
2007 Zhou H, Shatz W, Purdy MM, Fera N, Dahlquist FW, Reich NO. Long-range structural and dynamical changes induced by cofactor binding in DNA methyltransferase M.HhaI. Biochemistry. 46: 7261-8. PMID 17523600 DOI: 10.1021/Bi602662E  0.514
2007 Peterson SN, Dahlquist FW, Reich NO. The role of high affinity non-specific DNA binding by Lrp in transcriptional regulation and DNA organization. Journal of Molecular Biology. 369: 1307-17. PMID 17498742 DOI: 10.1016/J.Jmb.2007.04.023  0.727
2007 Braun G, Lee SJ, Dante M, Nguyen TQ, Moskovits M, Reich N. Surface-enhanced Raman spectroscopy for DNA detection by nanoparticle assembly onto smooth metal films. Journal of the American Chemical Society. 129: 6378-9. PMID 17469825 DOI: 10.1021/Ja070514Z  0.655
2007 Fabris L, Dante M, Braun G, Lee SJ, Reich NO, Moskovits M, Nguyen TQ, Bazan GC. A heterogeneous PNA-based SERS method for DNA detection. Journal of the American Chemical Society. 129: 6086-7. PMID 17451246 DOI: 10.1021/Ja0705184  0.667
2007 Wood DK, Braun GB, Fraikin JL, Swenson LJ, Reich NO, Cleland AN. A feasible approach to all-electronic digital labeling and readout for cell identification. Lab On a Chip. 7: 469-74. PMID 17389963 DOI: 10.1039/B616442K  0.611
2007 Zhou H, Shatz W, Purdy M, Fera N, Dahlquist F, Reich N. Backbone assignments of DNA methyltransferase M.HhaI Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr15170  0.474
2006 Youngblood B, Buller F, Reich NO. Determinants of sequence-specific DNA methylation: target recognition and catalysis are coupled in M.HhaI. Biochemistry. 45: 15563-72. PMID 17176077 DOI: 10.1021/Bi061414T  0.578
2006 Estabrook RA, Reich N. Observing an induced-fit mechanism during sequence-specific DNA methylation. The Journal of Biological Chemistry. 281: 37205-14. PMID 17005571 DOI: 10.1074/Jbc.M607538200  0.856
2006 Shieh FK, Youngblood B, Reich NO. The role of Arg165 towards base flipping, base stabilization and catalysis in M.HhaI. Journal of Molecular Biology. 362: 516-27. PMID 16926025 DOI: 10.1016/J.Jmb.2006.07.030  0.722
2006 Youngblood B, Shieh FK, De Los Rios S, Perona JJ, Reich NO. Engineered extrahelical base destabilization enhances sequence discrimination of DNA methyltransferase M.HhaI. Journal of Molecular Biology. 362: 334-46. PMID 16919299 DOI: 10.1016/J.Jmb.2006.07.031  0.724
2006 Youngblood B, Reich NO. Conformational transitions as determinants of specificity for the DNA methyltransferase EcoRI. The Journal of Biological Chemistry. 281: 26821-31. PMID 16845123 DOI: 10.1074/Jbc.M603388200  0.571
2006 Wu H, Lippmann JE, Oza JP, Zeng M, Fives-Taylor P, Reich NO. Inactivation of DNA adenine methyltransferase alters virulence factors in Actinobacillus actinomycetemcomitans Oral Microbiology and Immunology. 21: 238-244. PMID 16842508 DOI: 10.1111/J.1399-302X.2006.00284.X  0.365
2006 Mashhoon N, Pruss C, Carroll M, Johnson PH, Reich NO. Selective inhibitors of bacterial DNA adenine methyltransferases. Journal of Biomolecular Screening. 11: 497-510. PMID 16760373 DOI: 10.1177/1087057106287933  0.507
2006 Peterson SN, Reich NO. GATC flanking sequences regulate Dam activity: evidence for how Dam specificity may influence pap expression. Journal of Molecular Biology. 355: 459-72. PMID 16321401 DOI: 10.1016/J.Jmb.2005.11.003  0.702
2005 Svedruzić ZM, Reich NO. Mechanism of allosteric regulation of Dnmt1's processivity. Biochemistry. 44: 14977-88. PMID 16274244 DOI: 10.1021/Bi050988F  0.572
2005 Braun G, Inagaki K, Estabrook RA, Wood DK, Levy E, Cleland AN, Strouse GF, Reich NO. Gold nanoparticle decoration of DNA on silicon. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 10699-701. PMID 16262339 DOI: 10.1021/La0515367  0.801
2005 Koyfman AY, Braun G, Magonov S, Chworos A, Reich NO, Jaeger L. Controlled spacing of cationic gold nanoparticles by nanocrown RNA. Journal of the American Chemical Society. 127: 11886-7. PMID 16117496 DOI: 10.1021/Ja051144M  0.766
2005 Svedruzić ZM, Reich NO. DNA cytosine C5 methyltransferase Dnmt1: catalysis-dependent release of allosteric inhibition. Biochemistry. 44: 9472-85. PMID 15996102 DOI: 10.1021/Bi050295Z  0.557
2005 Oza JP, Yeh JB, Reich NO. DNA methylation modulates Salmonella enterica serovar Typhimurium virulence in Caenorhabditis elegans. Fems Microbiology Letters. 245: 53-9. PMID 15796979 DOI: 10.1016/J.Femsle.2005.02.030  0.34
2005 Yun CS, Javier A, Jennings T, Fisher M, Hira S, Peterson S, Hopkins B, Reich NO, Strouse GF. Nanometal surface energy transfer in optical rulers, breaking the FRET barrier Journal of the American Chemical Society. 127: 3115-3119. PMID 15740151 DOI: 10.1021/ja043940i  0.655
2005 Sharma V, Youngblood B, Reich N. Residues distal from the active site that alter enzyme function in M.HhaI DNA cytosine methyltransferase. Journal of Biomolecular Structure & Dynamics. 22: 533-43. PMID 15702925 DOI: 10.1080/07391102.2005.10507023  0.522
2005 Estabrook RA, Luo J, Purdy MM, Sharma V, Weakliem P, Bruice TC, Reich NO. Statistical coevolution analysis and molecular dynamics: identification of amino acid pairs essential for catalysis. Proceedings of the National Academy of Sciences of the United States of America. 102: 994-9. PMID 15657135 DOI: 10.1073/Pnas.0409128102  0.811
2005 Braun G, Inagaki K, Estabrook RA, Wood DK, Levy E, Strouse GF, Cleland AN, Reich NO. Gold nanoparticle decoration of DNA on silicon 2nd Conference On Foundations of Nanoscience: Self-Assembled Architectures and Devices, Fnano 2005. 214-215.  0.81
2004 Mashhoon N, Carroll M, Pruss C, Eberhard J, Ishikawa S, Estabrook RA, Reich N. Functional characterization of Escherichia coli DNA adenine methyltransferase, a novel target for antibiotics. The Journal of Biological Chemistry. 279: 52075-81. PMID 15456775 DOI: 10.1074/Jbc.M408182200  0.852
2004 Svedruzić ZM, Reich NO. The mechanism of target base attack in DNA cytosine carbon 5 methylation. Biochemistry. 43: 11460-73. PMID 15350132 DOI: 10.1021/Bi0496743  0.481
2004 Hopkins BB, Reich NO. Simultaneous DNA binding, bending, and base flipping: evidence for a novel M.EcoRI methyltransferase-DNA complex. The Journal of Biological Chemistry. 279: 37049-60. PMID 15210696 DOI: 10.1074/Jbc.M404573200  0.547
2004 Estabrook RA, Lipson R, Hopkins B, Reich N. The coupling of tight DNA binding and base flipping: identification of a conserved structural motif in base flipping enzymes. The Journal of Biological Chemistry. 279: 31419-28. PMID 15143064 DOI: 10.1074/Jbc.M402950200  0.857
2003 Hiller DA, Fogg JM, Martin AM, Beechem JM, Reich NO, Perona JJ. Simultaneous DNA binding and bending by EcoRV endonuclease observed by real-time fluorescence. Biochemistry. 42: 14375-85. PMID 14661948 DOI: 10.1021/Bi035520W  0.716
2003 Aubol BE, Reich NO. Murine DNA cytosine C(5)-methyltransferase: in vitro studies of de novo methylation spreading. Biochemical and Biophysical Research Communications. 310: 209-14. PMID 14511672 DOI: 10.1016/J.Bbrc.2003.08.138  0.549
2003 Malygin EG, Lindstrom WM, Zinoviev VV, Evdokimov AA, Schlagman SL, Reich NO, Hattman S. Bacteriophage T4Dam (DNA-(adenine-N6)-methyltransferase): evidence for two distinct stages of methylation under single turnover conditions. The Journal of Biological Chemistry. 278: 41749-55. PMID 12893823 DOI: 10.1074/Jbc.M306397200  0.82
2003 Roberts RJ, Belfort M, Bestor T, Bhagwat AS, Bickle TA, Bitinaite J, Blumenthal RM, Degtyarev SKh, Dryden DT, Dybvig K, Firman K, Gromova ES, Gumport RI, Halford SE, Hattman S, ... ... Reich N, et al. A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes. Nucleic Acids Research. 31: 1805-12. PMID 12654995 DOI: 10.1093/Nar/Gkg274  0.421
2003 Malygin EG, Zinoviev VV, Evdokimov AA, Lindstrom WM, Reich NO, Hattman S. DNA (cytosine-N4-)- and -(adenine-N6-)-methyltransferases have different kinetic mechanisms but the same reaction route. A comparison of M.BamHI and T4 Dam. The Journal of Biological Chemistry. 278: 15713-9. PMID 12598537 DOI: 10.1074/jbc.M213213200  0.827
2003 Lindstrom WM, Malygin EG, Ovechkina LG, Zinoviev VV, Reich NO. Functional analysis of BamHI DNA cytosine-N4 methyltransferase. Journal of Molecular Biology. 325: 711-20. PMID 12507474 DOI: 10.1016/S0022-2836(02)01282-2  0.837
2003 Flynn J, Fang JY, Mikovits JA, Reich NO. A potent cell-active allosteric inhibitor of murine DNA cytosine C5 methyltransferase. The Journal of Biological Chemistry. 278: 8238-43. PMID 12477724 DOI: 10.1074/Jbc.M209839200  0.556
2002 Yun CS, Khitrov GA, Vergona DE, Reich NO, Strouse GF. Enzymatic manipulation of DNA-nanomaterial constructs Journal of the American Chemical Society. 124: 7644-7645. PMID 12083903 DOI: 10.1021/Ja025971O  0.566
2001 Malygin EG, Evdokimov AA, Zinoviev VV, Ovechkina LG, Lindstrom WM, Reich NO, Schlagman SL, Hattman S. A dual role for substrate S-adenosyl-L-methionine in the methylation reaction with bacteriophage T4 Dam DNA-[N6-adenine]-methyltransferase. Nucleic Acids Research. 29: 2361-9. PMID 11376154 DOI: 10.1093/Nar/29.11.2361  0.819
2001 Malygin EG, Ovechkina LG, Zinoviev VV, Lindstrem UM, Reich NO. DNA-(N4-Cytosine)-methyltransferase from bacillus amyloliquefaciens: Kinetic and substrate-binding properties Molekulyarnaya Biologiya. 35: 42-51. PMID 11234382 DOI: 10.1023/A:1004846600495  0.507
2001 Eberhard J, Oza J, Reich NO. Cloning, sequence analysis and heterologous expression of the DNA adenine-(N6) methyltransferase from the human pathogen Actinobacillus actinomycetemcomitans Fems Microbiology Letters. 195: 223-229. PMID 11179656 DOI: 10.1111/J.1574-6968.2001.Tb10525.X  0.417
2000 Wong DL, Reich NO. Identification of tyrosine 204 as the photo-cross-linking site in the DNA-EcoRI DNA methyltransferase complex by electrospray ionization mass spectrometry Biochemistry. 39: 15410-15417. PMID 11112526 DOI: 10.1021/Bi001164V  0.508
2000 Malygin EG, Lindstrom WM, Schlagman SL, Hattman S, Reich NO. Pre-steady state kinetics of bacteriophage T4 dam DNA-[N(6)-adenine] methyltransferase: interaction with native (GATC) or modified sites. Nucleic Acids Research. 28: 4207-11. PMID 11058118 DOI: 10.1093/Nar/28.21.4207  0.805
2000 Szegedi SS, Reich NO, Gumport RI. Substrate binding in vitro and kinetics of RsrI [N6-adenine] DNA methyltransferase. Nucleic Acids Research. 28: 3962-71. PMID 11024176 DOI: 10.1093/Nar/28.20.3962  0.566
2000 Brunhuber NMW, Mort JL, Christoffersen RE, Reich NO. Steady-state kinetic mechanism of recombinant avocado ACC oxidase: Initial velocity and inhibitor studies Biochemistry. 39: 10730-10738. PMID 10978157 DOI: 10.1021/Bi0000162  0.339
2000 Lindstrom WM, Flynn J, Reich NO. Reconciling structure and function in HhaI DNA cytosine-C-5 methyltransferase. The Journal of Biological Chemistry. 275: 4912-9. PMID 10671528 DOI: 10.1074/Jbc.275.7.4912  0.84
1999 Martin AM, Horton NC, Lusetti S, Reich NO, Perona JJ. Divalent metal dependence of site-specific DNA binding by EcoRV endonuclease. Biochemistry. 38: 8430-9. PMID 10387089 DOI: 10.1021/Bi9905359  0.688
1999 Allan BW, Garcia R, Maegley K, Mort J, Wong D, Lindstrom W, Beechem JM, Reich NO. DNA bending by EcoRI DNA methyltransferase accelerates base flipping but compromises specificity Journal of Biological Chemistry. 274: 19269-19275. PMID 10383435 DOI: 10.1074/Jbc.274.27.19269  0.854
1999 Allan BW, Reich NO, Beechem JM. Measurement of the absolute temporal coupling between DNA binding and base flipping Biochemistry. 38: 5308-5314. PMID 10220317 DOI: 10.1021/Bi9900020  0.534
1999 Martin AM, Sam MD, Reich NO, Perona JJ. Structural and energetic origins of indirect readout in site-specific DNA cleavage by a restriction endonuclease. Nature Structural Biology. 6: 269-77. PMID 10074946 DOI: 10.1038/6707  0.745
1998 Flynn J, Reich N. Murine DNA (cytosine-5-)-methyltransferase: Steady-state and substrate trapping analyses of the kinetic mechanism Biochemistry. 37: 15162-15169. PMID 9790680 DOI: 10.1021/Bi9810609  0.56
1998 Flynn J, Azzam R, Reich N. DNA binding discrimination of the murine DNA cytosine-C5 methyltransferase Journal of Molecular Biology. 279: 101-116. PMID 9636703 DOI: 10.1006/Jmbi.1998.1761  0.561
1998 Allan BW, Beechem JM, Lindstrom WM, Reich NO. Direct real time observation of base flipping by the EcoRI DNA methyltransferase. The Journal of Biological Chemistry. 273: 2368-73. PMID 9442083 DOI: 10.1074/Jbc.273.4.2368  0.85
1998 Wong DL, Pavlovich JG, Reich NO. Electrospray ionization mass spectrometric characterization of photocrosslinked DNA-EcoRI DNA methyltransferase complexes Nucleic Acids Research. 26: 645-649. PMID 9421528 DOI: 10.1093/Nar/26.2.645  0.496
1997 Glickman JF, Pavlovich JG, Reich NO. Peptide mapping of the murine DNA methyltransferase reveals a major phosphorylation site and the start of translation Journal of Biological Chemistry. 272: 17851-17857. PMID 9211941 DOI: 10.1074/jbc.272.28.17851  0.411
1997 Glickman JF, Flynn J, Reich NO. Purification and characterization of recombinant baculovirus-expressed mouse DNA methyltransferase Biochemical and Biophysical Research Communications. 230: 280-284. PMID 9016766 DOI: 10.1006/bbrc.1996.5943  0.485
1997 Wong DL, Pavlovich JG, Reich NO. Identification of peptides involved in protein-dna recognition by electrospray ionization and maldi mass spectrometry Faseb Journal. 11: A1313.  0.354
1997 Allan BW, Beechem JM, Reich NO. Dynamic base-flipping by a DNA modifying enzyme Faseb Journal. 11: A1313.  0.438
1996 Allan BW, Reich NO. Targeted base stacking disruption by the EcoRI DNA methyltransferase Biochemistry. 35: 14757-14762. PMID 8942637 DOI: 10.1021/Bi9615708  0.525
1996 Garcia RA, Bustamante CJ, Reich NO. Sequence-specific recognition of cytosine C5 and adenine N6 DNA methyltransferases requires different deformations of DNA. Proceedings of the National Academy of Sciences of the United States of America. 93: 7618-22. PMID 8755524 DOI: 10.1073/pnas.93.15.7618  0.473
1996 Surby MA, Reich NO. Facilitated diffusion of the EcoRI DNA methyltransferase is described by a novel mechanism Biochemistry. 35: 2209-2217. PMID 8652562 DOI: 10.1021/Bi951884F  0.459
1996 Surby MA, Reich NO. Contribution of facilitated diffusion and processive catalysis to enzyme efficiency: Implications for the EcoRI restriction-modification system Biochemistry. 35: 2201-2208. PMID 8652561 DOI: 10.1021/Bi951883N  0.542
1996 Flynn J, Glickman JF, Reich NO. Murine DNA cytosine-C5 methyltransferase: Pre-steady- and steady-state kinetic analysis with regulatory DNA sequences Biochemistry. 35: 7308-7315. PMID 8652507 DOI: 10.1021/Bi9600512  0.568
1995 Xu G, Flynn J, Glickman JF, Reich NO. Purification and stabilization of mouse DNA methyltransferase Biochemical and Biophysical Research Communications. 207: 544-551. PMID 7864841 DOI: 10.1006/Bbrc.1995.1222  0.522
1994 Reich NO, Sweetnam KR. Sequence-dependent effects on DNA stability resulting from guanosine replacements by inosine Nucleic Acids Research. 22: 2089-2093. PMID 8029016 DOI: 10.1093/Nar/22.11.2089  0.504
1994 Mashhoon N, Reich NO. Investigation of ionizable residues critical for sequence-specific enzymatic DNA modification: Protein modification and steady-state and pre- steady-state kinetic pH analyses of EcoRI DNA methyltransferase Biochemistry. 33: 7113-7119. PMID 8003477 DOI: 10.1021/Bi00189A014  0.481
1994 Fraser Glickman J, Reich NO. Baculovirus-mediated high level expression of a mammalian DNA methyltransferase Biochemical and Biophysical Research Communications. 204: 1003-1008. PMID 7980570 DOI: 10.1006/Bbrc.1994.2562  0.453
1993 Reich NO, Mashhoon N. Presteady state kinetics of an S-adenosylmethionine-dependent enzyme. Evidence for a unique binding orientation requirement for EcoRI DNA methyltransferase Journal of Biological Chemistry. 268: 9191-9193. PMID 8486619  0.445
1993 Falsafi S, Reich NO. Molecular dynamics simulations of B-DNA: An analysis of the role of initial molecular configuration, randomly assigned velocity distribution, long integration times, and nonconstrained termini Biopolymers. 33: 459-473. PMID 8461453 DOI: 10.1002/Bip.360330312  0.468
1992 Reich NO, Olsen C, Osti F, Murphy J. In vitro specificity of EcoRI DNA methyltransferase Journal of Biological Chemistry. 267: 15802-15807. PMID 1639813  0.489
1992 Reich NO, Danzitz MJ. EcoRI DNA methyltransferase-DNA interactions Biochemistry®. 31: 1937-1945. PMID 1536835 DOI: 10.1021/Bi00122A006  0.588
1992 Maegley KA, Gonzalez L, Smith DW, Reich NO. Cofactor and DNA interactions in EcoRI DNA methyltransferase. Fluorescence spectroscopy and phenylalanine replacement for tryptophan 183 Journal of Biological Chemistry. 267: 18527-18532. PMID 1526989  0.37
1992 Smith DW, Crowder SW, Reich NO. In vivo specificity of EcoRI DNA methyltransferase Nucleic Acids Research. 20: 6091-6096. PMID 1461739 DOI: 10.1093/Nar/20.22.6091  0.546
1992 Lam WC, Tsao DH, Maki AH, Maegley KA, Reich NO. Spectroscopic studies of arsenic(III) binding to Escherichia coli RI methyltransferase and to two mutants, C223S and W183F. Biochemistry. 31: 10438-42. PMID 1420162 DOI: 10.1021/Bi00158A004  0.326
1991 Reich NO. Structural and functional analysis of EcoRI DNA methyltransferase by proteolysis Biochemistry. 30: 2940-2946. PMID 2007130 DOI: 10.1021/Bi00225A030  0.401
1991 Reich NO. Kinetic meenanism of the EcoRI DNA methyltransferase Biochemistry. 30: 2933-2939. PMID 2007129 DOI: 10.1021/Bi00225A029  0.582
1991 Reich NO, Danzitz Jnr. MJ. Non-additivity of sequence-specific enzyme-DNA interactions in the EcoRI DNA methyltransferase Nucleic Acids Research. 19: 6587-6594. PMID 1754395 DOI: 10.1093/nar/19.23.6587  0.492
1990 Reich NO, Mashhoon N. Inhibition of EcoRI DNA methylase with cofactor analogs Journal of Biological Chemistry. 265: 8966-8970. PMID 2341414  0.44
1990 Reich NO, Everett EA. Identification of peptides involved in S-adenosylmethionine binding in the EcoRI DNA methylase. Photoaffinity laveling with 8-azido-S-adenosylmethionine Journal of Biological Chemistry. 265: 8929-8934. PMID 2341412  0.344
1990 Hager PW, Reich NO, Day JP, Coche TG, Boyer HW, Rosenberg JM, Greene PJ. Probing the role of glutamic acid 144 in the EcoRI endonuclease using aspartic acid and glutamine replacements. The Journal of Biological Chemistry. 265: 21520-6. PMID 2254311  0.376
1990 Everett EA, Falick AM, Reich NO. Identification of a critical cysteine in EcoRI DNA methyltransferase by mass spectrometry Journal of Biological Chemistry. 265: 17713-17719. PMID 2170393  0.381
1989 Everett EA, Reich NO. Ecori DNA methylase activity is eliminated upon histidine residue modification Biochemical and Biophysical Research Communications. 164: 233-237. PMID 2803296 DOI: 10.1016/0006-291X(89)91707-5  0.448
1988 Salaün JP, Simon A, Durst F, Reich NO, Ortiz de Montellano PR. Differential inactivation of plant lauric acid omega- and in-chain-hydroxylases by terminally unsaturated fatty acids. Archives of Biochemistry and Biophysics. 260: 540-5. PMID 3341756 DOI: 10.1016/0003-9861(88)90479-1  0.415
1986 Reich NO, Ortiz de Montellano PR. Dissociation of increased lauric acid omega-hydroxylase activity from the antilipidemic action of clofibrate. Biochemical Pharmacology. 35: 1227-33. PMID 3964299 DOI: 10.1016/0006-2952(86)90264-9  0.426
1984 Salaun JP, Reichhart D, Simon A, Durst F, Reich NO, Ortiz de Montellano PR. Autocatalytic inactivation of plant cytochrome P-450 enzymes: selective inactivation of the lauric acid in-chain hydroxylase from Helianthus tuberosus L. by unsaturated substrate analogs. Archives of Biochemistry and Biophysics. 232: 1-7. PMID 6742847 DOI: 10.1016/0003-9861(84)90515-0  0.445
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