Jeffrey M. Macdonald - Publications

Affiliations: 
Biomedical Engineering Joint Program University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Biomedical

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Jeffries RE, Gomez SM, Macdonald JM, Gamcsik MP. Direct Detection of Glutathione Biosynthesis, Conjugation, Depletion and Recovery in Intact Hepatoma Cells. International Journal of Molecular Sciences. 23. PMID 35563124 DOI: 10.3390/ijms23094733  0.803
2019 Khanal S, Bhattarai SR, Sankar J, Bhandari RK, Macdonald JM, Bhattarai N. Nano-fibre Integrated Microcapsules: A Nano-in-Micro Platform for 3D Cell Culture. Scientific Reports. 9: 13951. PMID 31562351 DOI: 10.1038/S41598-019-50380-0  0.359
2018 Niemuth JN, Harms CA, Macdonald JM, Stoskopf MK. Propylene Glycol in Free-Ranging Green Sea Turtle Plasma Journal of Fish and Wildlife Management. 9: 617-623. DOI: 10.3996/122017-Jfwm-099  0.348
2017 Tikunov AP, Shim YS, Bhattarai N, Siler SQ, Soldatow V, LeCluyse EL, McDunn JE, Watkins PB, Macdonald JM. Dose-response in a high density three-dimensional liver device with real-time bioenergetic and metabolic flux quantification. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 28867505 DOI: 10.1016/J.Tiv.2017.08.021  0.399
2016 Pedersen JM, Shim YS, Hans V, Phillips MB, Macdonald JM, Walker G, Andersen ME, Clewell HJ, Yoon M. Fluid Dynamic Modeling to Support the Development of Flow-Based Hepatocyte Culture Systems for Metabolism Studies. Frontiers in Bioengineering and Biotechnology. 4: 72. PMID 27747210 DOI: 10.3389/Fbioe.2016.00072  0.361
2016 Yoon M, Phillips M, Billings D, Enders J, Balbuena P, Shim J, Burgunder E, Pedersen J, Macdonald J, Andersen M, Clewell H. Streamlining metabolite identification and toxicity testing using alginate supported 3D culture of primary hepatocytes Toxicology Letters. 258: S140. DOI: 10.1016/J.Toxlet.2016.06.1546  0.307
2016 Yoon M, Phillips M, Billings D, Balbuena P, Shim J, Burgunder E, Pedersen J, Enders J, Macdonald J, Andersen M, Clewell H. Liver bioreactor and incorporation of metabolism and biokinetics into the integrated cell-based toxicity system Toxicology Letters. 258: S31. DOI: 10.1016/J.Toxlet.2016.06.1219  0.359
2015 Jiang X, Jeffries RE, Acosta MA, Tikunov AP, Macdonald JM, Walker GM, Gamcsik MP. Biocompatibility of Tygon® tubing in microfluidic cell culture. Biomedical Microdevices. 17: 20. PMID 25653072 DOI: 10.1007/S10544-015-9938-9  0.773
2015 Tech K, Fish T, Crowther A, Tikunov A, Macdonald J, Gershon T. Pm-06Differential Splicing Of Pyruvate Kinase Regulates Progenitor Cell Cycle And Medulloblastoma Tumorigenesis. Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov061.128  0.3
2014 Tikunov AP, Stoskopf MK, Macdonald JM. Fluxomics of the eastern oyster for environmental stress studies. Metabolites. 4: 53-70. PMID 24958387 DOI: 10.3390/Metabo4010053  0.341
2013 McClelland R, Tech K, Macdonald JM. Construction of a multicoaxial hollow fiber bioreactor. Methods in Molecular Biology (Clifton, N.J.). 1001: 215-26. PMID 23494433 DOI: 10.1007/978-1-62703-363-3_19  0.31
2013 Jeffries RE, Gamcsik MP, Keshari KR, Pediaditakis P, Tikunov AP, Young GB, Lee H, Watkins PB, Macdonald JM. Effect of oxygen concentration on viability and metabolism in a fluidized-bed bioartificial liver using ³¹P and ¹³C NMR spectroscopy. Tissue Engineering. Part C, Methods. 19: 93-100. PMID 22835003 DOI: 10.1089/Ten.Tec.2011.0629  0.768
2013 Egan T, Dong B, Tikunov A, Semelka C, Kuan P-, Macdonald J. Metabolomic Profile of Rat Lung Tissue after Death: Effect of Delayed Post-Mortem O2-Ventilation Journal of Heart and Lung Transplantation. 32. DOI: 10.1016/J.Healun.2013.01.843  0.315
2013 Egan T, Dong B, Tikunov A, Semelka C, Blackwell J, Simmons W, Kuan P-, Macdonald J. Effect of Ex-Vivo Lung Perfusion (EVLP) on Metabolomic Profile of Human Lungs Journal of Heart and Lung Transplantation. 32. DOI: 10.1016/J.Healun.2013.01.638  0.343
2012 Keshari KR, Kurhanewicz J, Macdonald JM, Wilson DM. Generating contrast in hyperpolarized 13C MRI using ligand-receptor interactions. The Analyst. 137: 3427-9. PMID 22655289 DOI: 10.1039/C2An35406C  0.306
2012 Jeffries RE, Macdonald JM. New advances in MR-compatible bioartificial liver. Nmr in Biomedicine. 25: 427-42. PMID 22351642 DOI: 10.1002/Nbm.1633  0.777
2012 Johnson CB, Tikunov AP, Lee H, Wolak JE, Pediaditakis P, Romney DA, Holmuhamedov E, Gamcsik MP, Macdonald JM. ¹³C magnetic resonance spectroscopy detection of changes in serine isotopomers reflects changes in mitochondrial redox status. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 68: 671-9. PMID 22190282 DOI: 10.1002/Mrm.23296  0.383
2012 Thelwall PE, Simpson NE, Rabbani ZN, Clark MD, Pourdeyhimi R, Macdonald JM, Blackband SJ, Gamcsik MP. In vivo MR studies of glycine and glutathione metabolism in a rat mammary tumor. Nmr in Biomedicine. 25: 271-8. PMID 21751272 DOI: 10.1002/Nbm.1745  0.38
2012 Winnike JH, Pediaditakis P, Wolak JE, McClelland RE, Watkins PB, Macdonald JM. Stable isotope resolved metabolomics of primary human hepatocytes reveals a stressed phenotype Metabolomics. 8: 34-49. DOI: 10.1007/S11306-011-0284-5  0.763
2012 Wolak J, Rahimi-Keshari K, Jeffries RE, Joy MP, Todd A, Pediatitakis P, Dewar BJ, Winnike JH, Favorov O, Elston TC, Graves LM, Kurhanewicz J, Vigneron D, Holmuhamedov E, MacDonald JM. Noninvasive fluxomics in mammals by nuclear magnetic resonance spectroscopy Methods in Pharmacology and Toxicology. 17: 321-392. DOI: 10.1007/978-1-61779-618-0_11  0.642
2011 Tikunov AP, Lee H, Stoskopf MK, Macdonald JM. Application of Magnetic Resonance for Metabolomic Investigation of Mollusks Biophysical Journal. 100: 606a. DOI: 10.1016/J.Bpj.2010.12.3490  0.436
2010 Tikunov AP, Johnson CB, Lee H, Stoskopf MK, Macdonald JM. Metabolomic investigations of American oysters using H-NMR spectroscopy. Marine Drugs. 8: 2578-96. PMID 21116407 DOI: 10.3390/Md8102578  0.42
2010 Lee H, Tikunov A, Stoskopf MK, Macdonald JM. Applications of chemical shift imaging to marine sciences. Marine Drugs. 8: 2369-83. PMID 20948912 DOI: 10.3390/Md8082369  0.41
2010 Dewar BJ, Keshari K, Jeffries R, Dzeja P, Graves LM, Macdonald JM. Metabolic assessment of a novel chronic myelogenous leukemic cell line and an imatinib resistant subline by H NMR spectroscopy. Metabolomics : Official Journal of the Metabolomic Society. 6: 439-450. PMID 20676217 DOI: 10.1007/S11306-010-0204-0  0.781
2010 Wilson DM, Keshari KR, Larson PE, Chen AP, Hu S, Van Criekinge M, Bok R, Nelson SJ, Macdonald JM, Vigneron DB, Kurhanewicz J. Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 205: 141-7. PMID 20478721 DOI: 10.1016/J.Jmr.2010.04.012  0.306
2010 Winnike JH, Li Z, Wright FA, Macdonald JM, O'Connell TM, Watkins PB. Use of pharmaco-metabonomics for early prediction of acetaminophen-induced hepatotoxicity in humans. Clinical Pharmacology and Therapeutics. 88: 45-51. PMID 20182423 DOI: 10.1038/Clpt.2009.240  0.741
2010 Keshari KR, Kurhanewicz J, Jeffries RE, Wilson DM, Dewar BJ, Van Criekinge M, Zierhut M, Vigneron DB, Macdonald JM. Hyperpolarized (13)C spectroscopy and an NMR-compatible bioreactor system for the investigation of real-time cellular metabolism. Magnetic Resonance in Medicine. 63: 322-9. PMID 20099325 DOI: 10.1002/Mrm.22225  0.787
2010 Fannin RD, Russo M, O'Connell TM, Gerrish K, Winnike JH, Macdonald J, Newton J, Malik S, Sieber SO, Parker J, Shah R, Zhou T, Watkins PB, Paules RS. Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation. Hepatology (Baltimore, Md.). 51: 227-36. PMID 19918972 DOI: 10.1002/Hep.23330  0.746
2010 Holmuhamedov EL, Teplova VV, Johnson CB, MacDonald J. A study of the effect of ethanol on the synthesis of serine and the exchange of methyl groups in hepatocytes by NMR spectroscopy Biophysics. 55: 966-970. DOI: 10.1134/S0006350910060138  0.309
2010 Holmuhamedov EL, Czerny C, Lovelace G, Beeson CC, Baker T, Johnson CB, Pediaditakis P, Teplova VV, Tikunov A, MacDonald J, Lemasters JJ. Role of voltage-dependent anion channels of the mitochondrial outer membrane in regulation of cell metabolism Biophysics. 55: 733-739. DOI: 10.1134/S0006350910050088  0.314
2009 Keshari KR, Wilson DM, Chen AP, Bok R, Larson PE, Hu S, Van Criekinge M, Macdonald JM, Vigneron DB, Kurhanewicz J. Hyperpolarized [2-13C]-fructose: a hemiketal DNP substrate for in vivo metabolic imaging. Journal of the American Chemical Society. 131: 17591-6. PMID 19860409 DOI: 10.1021/Ja9049355  0.351
2008 Seagle C, Christie MA, Winnike JH, McClelland RE, Ludlow JW, O'Connell TM, Gamcsik MP, MacDonald JM. High-throughput nuclear magnetic resonance metabolomic footprinting for tissue engineering. Tissue Engineering. Part C, Methods. 14: 107-18. PMID 18544027 DOI: 10.1089/Ten.Tec.2007.0401  0.753
2008 Li C, Charlton LM, Lakkavaram A, Seagle C, Wang G, Young GB, Macdonald JM, Pielak GJ. Differential dynamical effects of macromolecular crowding on an intrinsically disordered protein and a globular protein: implications for in-cell NMR spectroscopy. Journal of the American Chemical Society. 130: 6310-1. PMID 18419123 DOI: 10.1021/Ja801020Z  0.744
2008 Turner WS, Seagle C, Galanko JA, Favorov O, Prestwich GD, Macdonald JM, Reid LM. Nuclear magnetic resonance metabolomic footprinting of human hepatic stem cells and hepatoblasts cultured in hyaluronan-matrix hydrogels. Stem Cells (Dayton, Ohio). 26: 1547-55. PMID 18323408 DOI: 10.1634/Stemcells.2007-0863  0.781
2008 Nicholas PC, Kim D, Crews FT, Macdonald JM. 1H NMR-based metabolomic analysis of liver, serum, and brain following ethanol administration in rats. Chemical Research in Toxicology. 21: 408-20. PMID 18095657 DOI: 10.1021/Tx700324T  0.679
2006 Nicholas PC, Kim D, Crews FT, Macdonald JM. Proton nuclear magnetic resonance spectroscopic determination of ethanol-induced formation of ethyl glucuronide in liver. Analytical Biochemistry. 358: 185-91. PMID 17027904 DOI: 10.1016/J.Ab.2006.08.033  0.7
2006 Chandrasekaran P, Seagle C, Rice L, Macdonald J, Gerber DA. Functional analysis of encapsulated hepatic progenitor cells. Tissue Engineering. 12: 2001-8. PMID 16889528 DOI: 10.1089/Ten.2006.12.2001  0.744
2005 Thelwall PE, Yemin AY, Gillian TL, Simpson NE, Kasibhatla MS, Rabbani ZN, Macdonald JM, Blackband SJ, Gamcsik MP. Noninvasive in vivo detection of glutathione metabolism in tumors. Cancer Research. 65: 10149-53. PMID 16287997 DOI: 10.1158/0008-5472.Can-05-1781  0.381
2002 Macdonald JM, Schmidlin O, James TL. In vivo monitoring of hepatic glutathione in anesthetized rats by 13C NMR. Magnetic Resonance in Medicine. 48: 430-9. PMID 12210907 DOI: 10.1002/Mrm.10244  0.37
2002 Wolfe SP, Hsu E, Reid LM, Macdonald JM. A novel multi-coaxial hollow fiber bioreactor for adherent cell types. Part 1: hydrodynamic studies. Biotechnology and Bioengineering. 77: 83-90. PMID 11745176 DOI: 10.1002/Bit.10081  0.36
2000 Macdonald JM, Haas AL, London RE. Novel mechanism of surface catalysis of protein adduct formation. NMR studies of the acetylation of ubiquitin. The Journal of Biological Chemistry. 275: 31908-13. PMID 10906321 DOI: 10.1074/Jbc.M000684200  0.339
1999 Xu ASL, Macdonald JM, Labotka RJ, London RE. NMR study of the sites of human hemoglobin acetylated by aspirin Biochimica Et Biophysica Acta - Protein Structure and Molecular Enzymology. 1432: 333-349. PMID 10407155 DOI: 10.1016/S0167-4838(99)00094-1  0.368
1999 Macdonald JM, LeBlanc DA, Haas AL, London RE. An NMR analysis of the reaction of ubiquitin with [acetyl-1-13C]aspirin. Biochemical Pharmacology. 57: 1233-44. PMID 10230767 DOI: 10.1016/S0006-2952(99)00039-8  0.336
1998 Macdonald JM, Grillo M, Schmidlin O, Tajiri DT, James TL. NMR spectroscopy and MRI investigation of a potential bioartificial liver. Nmr in Biomedicine. 11: 55-66. PMID 9608589 DOI: 10.1002/(Sici)1099-1492(199804)11:2<55::Aid-Nbm502>3.0.Co;2-F  0.411
1998 Espanol MT, Litt L, Hasegawa K, Chang LH, Macdonald JM, Gregory G, James TL, Chan PH. Fructose-1,6-bisphosphate preserves adenosine triphosphate but not intracellular pH during hypoxia in respiring neonatal rat brain slices. Anesthesiology. 88: 461-72. PMID 9477067 DOI: 10.1097/00000542-199802000-00025  0.448
1993 Macdonald JM, Kurhanewicz J, Dahiya R, Espanol MT, Chang LH, Goldberg B, James TL, Narayan P. Effect of glucose and confluency on phosphorus metabolites of perfused human prostatic adenocarcinoma cells as determined by 31P MRS. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 29: 244-8. PMID 8429789 DOI: 10.1002/Mrm.1910290213  0.345
1992 Kurhanewicz J, Dahiya R, Macdonald JM, Jajodia P, Chang LH, James TL, Narayan P. Phosphorus metabolite characterization of human prostatic adenocarcinoma in a nude mouse model by 31P magnetic resonance spectroscopy and high pressure liquid chromatography. Nmr in Biomedicine. 5: 185-92. PMID 1449954 DOI: 10.1002/Nbm.1940050405  0.336
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