| Year |
Citation |
Score |
| 2023 |
Green-Fulgham SM, Lacagnina MJ, Willcox KF, Li J, Harland ME, Ciena AP, Rocha IRC, Ball JB, Dreher RA, Zuberi YA, Dragavon J, Chacur M, Maier SF, Watkins LR, Grace PM. Voluntary wheel running prevents formation of membrane attack complexes and myelin degradation after peripheral nerve injury. Brain, Behavior, and Immunity. PMID 37924957 DOI: 10.1016/j.bbi.2023.10.027 |
0.795 |
|
| 2023 |
Green-Fulgham SM, Ball JB, Kwilasz AJ, Harland ME, Frank MG, Dragavon JM, Grace PM, Watkins LR. Interleukin-1beta and inflammasome expression in spinal cord following chronic constriction injury in male and female rats. Brain, Behavior, and Immunity. 115: 157-168. PMID 37838078 DOI: 10.1016/j.bbi.2023.10.004 |
0.776 |
|
| 2022 |
Kwilasz AJ, Clements MA, Larson TA, Harris KM, Litwiler ST, Woodall BJ, Todd LS, Schrama AEW, Mitten EH, Maier SF, Van Dam AM, Rice KC, Watkins LR. Involvement of TLR2-TLR4, NLRP3, and IL-17 in pain induced by a novel Sprague-Dawley rat model of experimental autoimmune encephalomyelitis. Frontiers in Pain Research (Lausanne, Switzerland). 3: 932530. PMID 36176709 DOI: 10.3389/fpain.2022.932530 |
0.829 |
|
| 2022 |
Green-Fulgham SM, Harland ME, Ball JB, Li J, Lacagnina MJ, D'Angelo H, Dreher RA, Willcox KF, Lorca SA, Kwilasz AJ, Maier SF, Watkins LR, Grace PM. Preconditioning by voluntary wheel running attenuates later neuropathic pain via Nrf2 antioxidant signaling in rats. Pain. PMID 35486864 DOI: 10.1097/j.pain.0000000000002589 |
0.819 |
|
| 2021 |
Li H, Peng Y, Lin C, Zhang X, Zhang T, Wang Y, Li Y, Wu S, Wang H, Hutchinson MR, Watkins LR, Wang X. Nicotine and its metabolite cotinine target MD2 and inhibit TLR4 signaling. Innovation (New York, N.Y.). 2: 100111. PMID 34557761 DOI: 10.1016/j.xinn.2021.100111 |
0.679 |
|
| 2021 |
Gaudet AD, Fonken LK, Ayala MT, Maier SF, Watkins LR. Aging and miR-155 in mice influence survival and neuropathic pain after spinal cord injury. Brain, Behavior, and Immunity. PMID 34284114 DOI: 10.1016/j.bbi.2021.07.003 |
0.431 |
|
| 2021 |
Lacagnina MJ, Heijnen CJ, Watkins LR, Grace PM. Autoimmune regulation of chronic pain. Pain Reports. 6: e905. PMID 33981931 DOI: 10.1097/PR9.0000000000000905 |
0.825 |
|
| 2020 |
Kwilasz AJ, Green Fulgham SM, Chante Duran-Malle J, Schrama AEW, Mitten EH, Todd LS, Patel HP, Larson TA, Clements MA, Harris KM, Litwiler ST, Harvey LO, Maier SF, Chavez RA, Rice KC, ... ... Watkins LR, et al. Toll-like receptor 2 and 4 antagonism for the treatment of experimental autoimmune encephalitis (EAE)-related pain. Brain, Behavior, and Immunity. PMID 33358978 DOI: 10.1016/j.bbi.2020.12.016 |
0.834 |
|
| 2020 |
Muscat SM, Deems NP, D'Angelo H, Kitt MM, Grace PM, Andersen ND, Silverman SN, Rice KC, Watkins LR, Maier SF, Barrientos RM. Postoperative cognitive dysfunction is made persistent with morphine treatment in aged rats. Neurobiology of Aging. 98: 214-224. PMID 33341652 DOI: 10.1016/j.neurobiolaging.2020.11.008 |
0.784 |
|
| 2020 |
Kwilasz AJ, Todd LS, Duran-Malle JC, Schrama AEW, Mitten EH, Larson TA, Clements MA, Harris KM, Litwiler ST, Wang X, Van Dam AM, Maier SF, Rice KC, Watkins LR, Barrientos RM. Experimental autoimmune encephalopathy (EAE)-induced hippocampal neuroinflammation and memory deficits are prevented with the non-opioid TLR2/TLR4 antagonist (+)-naltrexone. Behavioural Brain Research. 112896. PMID 32905811 DOI: 10.1016/J.Bbr.2020.112896 |
0.8 |
|
| 2020 |
Watkins LR, Chavez RA, Landry R, Fry M, Green-Fulgham SM, Coulson JD, Collins SD, Glover DK, Rieger J, Forsayeth JR. Targeted interleukin-10 plasmid DNA therapy in the treatment of osteoarthritis: Toxicology and pain efficacy assessments. Brain, Behavior, and Immunity. PMID 32800926 DOI: 10.1016/J.Bbi.2020.08.005 |
0.401 |
|
| 2020 |
Frank MG, Baratta MV, Zhang K, Fallon IP, Pearson MA, Liu G, Hutchinson MR, Watkins LR, Goldys EM, Maier SF. Acute stress induces the rapid and transient induction of caspase-1, gasdermin D and release of constitutive IL-1β protein in dorsal hippocampus. Brain, Behavior, and Immunity. PMID 32750541 DOI: 10.1016/J.Bbi.2020.07.042 |
0.749 |
|
| 2020 |
Green-Fulgham SM, Ball JB, Maier SF, Rice KC, Watkins LR, Grace PM. Suppression of active phase voluntary wheel running in male rats by unilateral chronic constriction injury: Enduring therapeutic effects of a brief treatment of morphine combined with TLR4 or P2X7 antagonists. Journal of Neuroscience Research. PMID 32533604 DOI: 10.1002/Jnr.24645 |
0.813 |
|
| 2020 |
Frank MG, Fonken LK, Watkins LR, Maier SF. Acute stress induces chronic neuroinflammatory, microglial and behavioral priming: A role for potentiated NLRP3 inflammasome activation. Brain, Behavior, and Immunity. PMID 32485293 DOI: 10.1016/J.Bbi.2020.05.063 |
0.521 |
|
| 2020 |
Doyle TM, Janes K, Chen Z, Grace PM, Esposito E, Cuzzocrea S, Largent-Milnes TM, Neumann WL, Watkins LR, Spiegel S, Vanderah TW, Salvemini D. Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents. Pain. PMID 32301840 DOI: 10.1097/J.Pain.0000000000001888 |
0.805 |
|
| 2019 |
Daut RA, Ravenel JR, Watkins LR, Maier SF, Fonken LK. The behavioral and neurochemical effects of an inescapable stressor are time of day dependent. Stress (Amsterdam, Netherlands). 1-27. PMID 31868091 DOI: 10.1080/10253890.2019.1707180 |
0.461 |
|
| 2019 |
Peng Y, Zhang X, Zhang T, Grace PM, Li H, Wang Y, Li H, Chen H, Watkins LR, Hutchinson MR, Yin H, Wang X. Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain. Brain, Behavior, and Immunity. PMID 31542403 DOI: 10.1016/J.Bbi.2019.09.013 |
0.831 |
|
| 2019 |
Green-Fulgham SM, Ball JB, Kwilasz AJ, Fabisiak T, Maier SF, Watkins LR, Grace PM. Oxycodone, fentanyl, and morphine amplify established neuropathic pain in male rats. Pain. PMID 31299018 DOI: 10.1097/J.Pain.0000000000001652 |
0.81 |
|
| 2019 |
Wang X, Northcutt AL, Cochran TA, Zhang X, Fabisiak TJ, Haas ME, Amat J, Li H, Rice KC, Maier S, Bachtell RK, Hutchinson MR, Watkins LR. Methamphetamine activates Toll-like receptor 4 to induce central immune signaling within the ventral tegmental area and contributes to extracellular dopamine increase in the nucleus accumbens shell. Acs Chemical Neuroscience. PMID 31282647 DOI: 10.1021/Acschemneuro.9B00225 |
0.82 |
|
| 2019 |
LaRocca TJ, Mariani A, Watkins LR, Link CD. TDP-43 knockdown causes innate immune activation via protein kinase R in astrocytes. Neurobiology of Disease. 104514. PMID 31229690 DOI: 10.1016/J.Nbd.2019.104514 |
0.302 |
|
| 2019 |
Zhang X, Peng Y, Grace PM, Metcalf MD, Kwilasz AJ, Wang Y, Zhang T, Wu S, Selfridge BR, Portoghese PS, Rice KC, Watkins LR, Hutchinson MR, Wang X. Stereochemistry and innate immune recognition: (+)-norbinaltorphimine targets myeloid differentiation protein 2 and inhibits toll-like receptor 4 signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900173RRR. PMID 31162938 DOI: 10.1096/Fj.201900173Rrr |
0.807 |
|
| 2019 |
Frank MG, Annis JL, Watkins LR, Maier SF. Glucocorticoids mediate stress induction of the alarmin HMGB1 and reduction of the microglia checkpoint receptor CD200R1 in limbic brain structures. Brain, Behavior, and Immunity. PMID 31078691 DOI: 10.1016/j.bbi.2019.05.014 |
0.491 |
|
| 2019 |
Frank MG, Fonken LK, Watkins LR, Maier SF. Microglia: Neuroimmune-sensors of stress. Seminars in Cell & Developmental Biology. PMID 30638704 DOI: 10.1016/J.Semcdb.2019.01.001 |
0.465 |
|
| 2019 |
Ball J, Green-Fulgham S, Watkins L, Grace P. (351) The Opioids Oxycodone, Fentanyl, and Morphine Amplify Neuropathic when Given after Chronic Pain is Established The Journal of Pain. 20: S62. DOI: 10.1016/J.Jpain.2019.02.047 |
0.796 |
|
| 2019 |
Gaudet A, Fonken L, Ayala M, Bateman E, Schleicher W, Smith E, D’Angelo H, Maier S, Watkins L. Abstract # 3188 Spinal cord injury perturbs circadian rhythms Brain, Behavior, and Immunity. 76: e39. DOI: 10.1016/J.Bbi.2018.11.298 |
0.303 |
|
| 2019 |
Fonken L, Frank M, D’Angelo H, Watkins L, Lowry C, Maier S. Abstract # 3175 Mycobacterium vaccae immunization protects aged rats from surgery-elicited neuroinflammation and cognitive dysfunction Brain, Behavior, and Immunity. 76: e36. DOI: 10.1016/J.Bbi.2018.11.286 |
0.487 |
|
| 2019 |
Kwilasz AJ, Todd LS, Duran-Malle LC, Schrama AE, Mitten EH, Dam AMV, Maier SF, Rice KC, Watkins LR, Barrientos RM. Abstract # 3170 The TLR2/4 antagonist (+)-naltrexone blocks contextual long-term memory deficits in experimental autoimmune encephalitis and associated neuroinflammation in hippocampus Brain Behavior and Immunity. 76. DOI: 10.1016/J.Bbi.2018.11.282 |
0.358 |
|
| 2019 |
Frank M, Annis J, Watkins L, Maier S. Abstract # 2044 Glucocorticoids mediate stress-induced upregulation of the alarmin HMGB1 and downregulation of the inhibitory receptor CD200R1 in hippocampus and amygdala: A mechanism of neuroinflammatory priming Brain, Behavior, and Immunity. 76: e2-e3. DOI: 10.1016/j.bbi.2018.11.177 |
0.514 |
|
| 2018 |
Gaudet AD, Fonken LK, Ayala MT, Bateman EM, Schleicher WE, Smith EJ, D'Angelo HM, Maier SF, Watkins LR. Spinal Cord Injury in Rats Disrupts the Circadian System. Eneuro. 5. PMID 30627655 DOI: 10.1523/ENEURO.0328-18.2018 |
0.427 |
|
| 2018 |
Gaudet AD, Fonken LK, Ayala MT, D'Angelo HM, Smith EJ, Bateman EM, Schleicher WE, Maier SF, Watkins L. Spinal cord injury in rats dysregulates diurnal rhythms of fecal output and liver metabolic indicators. Journal of Neurotrauma. PMID 30501584 DOI: 10.1089/Neu.2018.6101 |
0.46 |
|
| 2018 |
Kwilasz AJ, Green Fulgham SM, Ellis A, Patel HP, Duran-Malle JC, Favret J, Harvey LO, Rieger J, Maier SF, Watkins LR. A single peri-sciatic nerve administration of the adenosine 2A receptor agonist ATL313 produces long-lasting anti-allodynia and anti-inflammatory effects in male rats. Brain, Behavior, and Immunity. PMID 30453021 DOI: 10.1016/J.Bbi.2018.11.011 |
0.769 |
|
| 2018 |
Daut RA, Hartsock MJ, Tomczik AC, Watkins LR, Spencer RL, Maier SF, Fonken LK. Circadian misalignment has differential effects on affective behavior following exposure to controllable or uncontrollable stress. Behavioural Brain Research. PMID 30312639 DOI: 10.1016/J.Bbr.2018.10.013 |
0.454 |
|
| 2018 |
Fonken LK, Frank MG, D'Angelo HM, Heinze JD, Watkins LR, Lowry CA, Maier SF. Mycobacterium vaccae immunization protects aged rats from surgery-elicited neuroinflammation and cognitive dysfunction. Neurobiology of Aging. 71: 105-114. PMID 30118926 DOI: 10.1016/J.Neurobiolaging.2018.07.012 |
0.469 |
|
| 2018 |
Frank MG, Fonken LK, Watkins LR, Maier SF, Lowry CA. Could Probiotics Be Used to Mitigate Neuroinflammation? Acs Chemical Neuroscience. PMID 30109920 DOI: 10.1021/Acschemneuro.8B00386 |
0.471 |
|
| 2018 |
Frank MG, Fonken LK, Dolzani SD, Annis JL, Siebler PH, Schmidt D, Watkins LR, Maier SF, Lowry CA. Immunization with Mycobacterium vaccae induces an anti-inflammatory milieu in the CNS: Attenuation of stress-induced microglial priming, alarmins and anxiety-like behavior. Brain, Behavior, and Immunity. PMID 29807129 DOI: 10.1016/J.Bbi.2018.05.020 |
0.503 |
|
| 2018 |
Grace PM, Strand KA, Galer EL, Maier SF, Watkins LR. MicroRNA-124 and microRNA-146a both attenuate persistent neuropathic pain induced by morphine in male rats. Brain Research. PMID 29723521 DOI: 10.1016/J.Brainres.2018.04.038 |
0.778 |
|
| 2018 |
Zhang K, Baratta MV, Liu G, Frank MG, Leslie NR, Watkins LR, Maier SF, Hutchinson MR, Goldys EM. A novel platform for in vivo detection of cytokine release within discrete brain regions. Brain, Behavior, and Immunity. PMID 29678795 DOI: 10.1016/J.Bbi.2018.04.011 |
0.747 |
|
| 2018 |
Grace PM, Galer EL, Strand KA, Corrigan K, Berkelhammer D, Maier SF, Watkins LR. Repeated Morphine Prolongs Postoperative Pain in Male Rats. Anesthesia and Analgesia. PMID 29596097 DOI: 10.1213/Ane.0000000000003345 |
0.828 |
|
| 2018 |
Grace PM, Wang X, Strand KA, Baratta MV, Zhang Y, Galer EL, Yin H, Maier SF, Watkins LR. DREADDed microglia in pain: Implications for spinal inflammatory signaling in male rats. Experimental Neurology. PMID 29530713 DOI: 10.1016/J.Expneurol.2018.03.005 |
0.825 |
|
| 2018 |
Fonken LK, Frank MG, Gaudet AD, D'Angelo HM, Daut RA, Hampson EC, Ayala MT, Watkins LR, Maier SF. Neuroinflammatory priming to stress is differentially regulated in male and female rats. Brain, Behavior, and Immunity. PMID 29524458 DOI: 10.1016/J.Bbi.2018.03.005 |
0.482 |
|
| 2018 |
Zhang X, Cui F, Chen H, Zhang T, Yang K, Wang Y, Jiang Z, Rice KC, Watkins LR, Hutchinson MR, Li Y, Peng Y, Wang X. Dissecting the Innate Immune Recognition of Opioid Inactive Isomer (+)-Naltrexone Derived Toll-like Receptor 4 (TLR4) Antagonists. Journal of Chemical Information and Modeling. PMID 29518316 DOI: 10.1021/Acs.Jcim.7B00717 |
0.736 |
|
| 2018 |
Dolzani SD, Baratta MV, Moss JM, Leslie NL, Tilden SG, Sørensen AT, Watkins LR, Lin Y, Maier SF. Inhibition of a Descending Prefrontal Circuit Prevents Ketamine-Induced Stress Resilience in Females. Eneuro. 5. PMID 29516036 DOI: 10.1523/ENEURO.0025-18.2018 |
0.415 |
|
| 2018 |
Kwilasz AJ, Ellis A, Wieseler J, Loram L, Favret J, McFadden A, Springer K, Falci S, Rieger J, Maier SF, Watkins LR. Sustained Reversal of Central Neuropathic Pain Induced by a Single Intrathecal Injection of Adenosine A2A Receptor Agonists. Brain, Behavior, and Immunity. PMID 29366930 DOI: 10.1016/J.Bbi.2018.01.005 |
0.791 |
|
| 2018 |
Baratta MV, Leslie NR, Fallon IP, Dolzani SD, Chun LE, Tamalunas AM, Watkins LR, Maier SF. Behavioral and neural sequelae of stressor exposure are not modulated by controllability in females. The European Journal of Neuroscience. PMID 29359831 DOI: 10.1111/Ejn.13833 |
0.469 |
|
| 2017 |
Frank MG, Fonken LK, Annis JL, Watkins LR, Maier SF. Stress disinhibits microglia via down-regulation of CD200R: a mechanism of neuroinflammatory priming. Brain, Behavior, and Immunity. PMID 29104062 DOI: 10.1016/J.Bbi.2017.11.001 |
0.487 |
|
| 2017 |
Lacagnina MJ, Watkins LR, Grace PM. Toll-like receptors and their role in persistent pain. Pharmacology & Therapeutics. PMID 28987324 DOI: 10.1016/J.Pharmthera.2017.10.006 |
0.836 |
|
| 2017 |
Grace PM, Strand KA, Galer EL, Rice KC, Maier SF, Watkins LR. Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats. Brain, Behavior, and Immunity. PMID 28860068 DOI: 10.1016/J.Bbi.2017.08.018 |
0.823 |
|
| 2017 |
Brown KT, Levis SC, O'Neill CE, Northcutt AL, Fabisiak TJ, Watkins LR, Bachtell RK. Innate Immune Signaling in the Ventral Tegmental Area Contributes to Drug-Primed Reinstatement of Cocaine Seeking. Brain, Behavior, and Immunity. PMID 28813640 DOI: 10.1016/J.Bbi.2017.08.012 |
0.785 |
|
| 2017 |
Spencer SJ, D'Angelo H, Soch A, Watkins LR, Maier SF, Barrientos RM. High-fat diet and aging interact to produce neuroinflammation and impair hippocampal- and amygdalar-dependent memory. Neurobiology of Aging. 58: 88-101. PMID 28719855 DOI: 10.1016/j.neurobiolaging.2017.06.014 |
0.465 |
|
| 2017 |
Gaudet AD, Ayala MT, Schleicher WE, Smith EJ, Bateman EM, Maier SF, Watkins LR. Exploring acute-to-chronic neuropathic pain in rats after contusion spinal cord injury. Experimental Neurology. PMID 28552717 DOI: 10.1016/j.expneurol.2017.05.011 |
0.59 |
|
| 2017 |
Lacagnina MJ, Kopec AM, Cox SS, Hanamsagar R, Wells C, Slade S, Grace PM, Watkins LR, Levin ED, Bilbo SD. Opioid Self-Administration is Attenuated by Early-Life Experience and Gene Therapy for Anti-Inflammatory IL-10 in the Nucleus Accumbens of Male Rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28436446 DOI: 10.1038/Npp.2017.82 |
0.813 |
|
| 2017 |
Wieseler J, Ellis A, McFadden A, Stone K, Brown K, Cady S, Bastos LF, Sprunger D, Rezvani N, Johnson K, Rice KC, Maier SF, Watkins LR. Supradural inflammatory soup in awake and freely moving rats induces facial allodynia that is blocked by putative immune modulators. Brain Research. PMID 28322750 DOI: 10.1016/J.Brainres.2017.03.011 |
0.758 |
|
| 2017 |
McDonnell B, Kullmann A, Wolf-Johnston A, Kanai A, Grace P, Watkins L, Rodriguez L, Birder L. Pd01-03 Stress-Induced Adrenergic Dysregulation Alters Neural-Glial Distribution And Phenotype The Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.183 |
0.714 |
|
| 2016 |
Grace P, Strand K, Galer E, Anderson N, Fabisiak T, Fulgham S, Greenwood B, Fleshner M, Maier S, Watkins L. (464) Prior voluntary wheel running is protective for neuropathic-like pain. The Journal of Pain : Official Journal of the American Pain Society. 17: S90. PMID 28162718 DOI: 10.1016/J.Jpain.2016.01.441 |
0.802 |
|
| 2016 |
Lewis SS, Grace PM, Hutchinson MR, Maier SF, Watkins LR. Constriction of the buccal branch of the facial nerve produces unilateral craniofacial allodynia. Brain, Behavior, and Immunity. PMID 27993689 DOI: 10.1016/J.Bbi.2016.12.004 |
0.815 |
|
| 2016 |
Frank MG, Weber MD, Watkins LR, Maier SF. Stress-induced neuroinflammatory priming: A liability factor in the etiology of psychiatric disorders. Neurobiology of Stress. 4: 62-70. PMID 27981190 DOI: 10.1016/j.ynstr.2015.12.004 |
0.494 |
|
| 2016 |
Barrientos RM, Kitt MM, D'Angelo HM, Watkins LR, Rudy JW, Maier SF. Stable, long-term, spatial memory in young and aged rats achieved with a one day Morris water maze training protocol. Learning & Memory (Cold Spring Harbor, N.Y.). 23: 699-702. PMID 27918274 DOI: 10.1101/lm.043489.116 |
0.431 |
|
| 2016 |
Grace PM, Gaudet AD, Staikopoulos V, Maier SF, Hutchinson MR, Salvemini D, Watkins LR. Nitroxidative Signaling Mechanisms in Pathological Pain. Trends in Neurosciences. PMID 27842920 DOI: 10.1016/J.Tins.2016.10.003 |
0.822 |
|
| 2016 |
Dolzani SD, Baratta MV, Amat J, Agster KL, Saddoris MP, Watkins LR, Maier SF. Activation of a Habenulo-Raphe Circuit Is Critical for the Behavioral and Neurochemical Consequences of Uncontrollable Stress in the Male Rat. Eneuro. 3. PMID 27785462 DOI: 10.1523/ENEURO.0229-16.2016 |
0.391 |
|
| 2016 |
Das N, Dewan V, Grace PM, Gunn RJ, Tamura R, Tzarum N, Watkins LR, Wilson IA, Yin H. HMGB1 Activates Proinflammatory Signaling via TLR5 Leading to Allodynia. Cell Reports. 17: 1128-1140. PMID 27760316 DOI: 10.1016/J.Celrep.2016.09.076 |
0.813 |
|
| 2016 |
Dodds KN, Beckett EA, Evans SF, Grace PM, Watkins LR, Hutchinson MR. Glial contributions to visceral pain: implications for disease etiology and the female predominance of persistent pain. Translational Psychiatry. 6: e888. PMID 27622932 DOI: 10.1038/Tp.2016.168 |
0.824 |
|
| 2016 |
Sobesky JL, D'Angelo HM, Weber MD, Anderson ND, Frank MG, Watkins LR, Maier SF, Barrientos RM. Glucocorticoids Mediate Short-Term High-Fat Diet Induction of Neuroinflammatory Priming, the NLRP3 Inflammasome, and the Danger Signal HMGB1. Eneuro. 3. PMID 27595136 DOI: 10.1523/ENEURO.0113-16.2016 |
0.419 |
|
| 2016 |
Fonken LK, Kitt MM, Gaudet AD, Barrientos RM, Watkins LR, Maier SF. Diminished circadian rhythms in hippocampal microglia may contribute to age-related neuroinflammatory sensitization. Neurobiology of Aging. 47: 102-112. PMID 27568094 DOI: 10.1016/J.Neurobiolaging.2016.07.019 |
0.481 |
|
| 2016 |
Ellis A, Grace PM, Wieseler J, Favret J, Springer K, Skarda B, Hutchinson MR, Falci S, Rice KC, Maier SF, Watkins LR. Morphine amplifies mechanical allodynia via TLR4 in a rat model of spinal cord injury. Brain, Behavior, and Immunity. PMID 27519154 DOI: 10.1016/J.Bbi.2016.08.004 |
0.832 |
|
| 2016 |
Fonken LK, Frank MG, Kitt MM, D'Angelo HM, Norden DM, Weber MD, Barrientos RM, Godbout JP, Watkins LR, Maier SF. The Alarmin HMGB1 Mediates Age-Induced Neuroinflammatory Priming. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7946-56. PMID 27466339 DOI: 10.1523/Jneurosci.1161-16.2016 |
0.503 |
|
| 2016 |
Grace PM, Fabisiak TJ, Green-Fulgham SM, Anderson ND, Strand KA, Kwilasz AJ, Galer EL, Walker FR, Greenwood BN, Maier SF, Fleshner M, Watkins LR. Prior voluntary wheel running attenuates neuropathic pain. Pain. PMID 27355182 DOI: 10.1097/J.Pain.0000000000000607 |
0.808 |
|
| 2016 |
Grace PM, Strand KA, Galer EL, Urban DJ, Wang X, Baratta MV, Fabisiak TJ, Anderson ND, Cheng K, Greene LI, Berkelhammer D, Zhang Y, Ellis AL, Yin HH, Campeau S, ... ... Watkins LR, et al. Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27247388 DOI: 10.1073/Pnas.1602070113 |
0.847 |
|
| 2016 |
Grace PM, Loram LC, Christianson JP, Strand KA, Flyer-Adams JG, Penzkover KR, Forsayeth JR, Dam AV, Mahoney MJ, Maier SF, Chavez RA, Watkins LR. Behavioral assessment of neuropathic pain, fatigue, and anxiety in experimental autoimmune encephalomyelitis (EAE) and attenuation by interleukin-10 gene therapy. Brain, Behavior, and Immunity. PMID 27189037 DOI: 10.1016/J.Bbi.2016.05.012 |
0.789 |
|
| 2016 |
Fonken LK, Weber MD, Daut RA, Kitt MM, Frank MG, Watkins LR, Maier SF. Stress-induced neuroinflammatory priming is time of day dependent. Psychoneuroendocrinology. 66: 82-90. PMID 26799851 DOI: 10.1016/J.Psyneuen.2016.01.006 |
0.476 |
|
| 2016 |
Amat J, Dolzani SD, Tilden S, Christianson JP, Kubala KH, Bartholomay K, Sperr K, Ciancio N, Watkins LR, Maier SF. Previous Ketamine Produces an Enduring Blockade of Neurochemical and Behavioral Effects of Uncontrollable Stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 153-61. PMID 26740657 DOI: 10.1523/Jneurosci.3114-15.2016 |
0.495 |
|
| 2015 |
Wang X, Zhang Y, Peng Y, Hutchinson MR, Rice KC, Yin H, Watkins LR. Pharmacological characterization of the opioid inactive isomers (+)-naltrexone and (+)-naloxone as Toll-like receptor 4 antagonists. British Journal of Pharmacology. PMID 26603732 DOI: 10.1111/Bph.13394 |
0.806 |
|
| 2015 |
Frank MG, Weber MD, Fonken LK, Hershman SA, Watkins LR, Maier SF. The redox state of the alarmin HMGB1 is a pivotal factor in neuroinflammatory and microglial priming: a role for the NLRP3 inflammasome. Brain, Behavior, and Immunity. PMID 26482581 DOI: 10.1016/J.Bbi.2015.10.009 |
0.527 |
|
| 2015 |
Frank MG, Adhikary S, Sobesky JL, Weber MD, Watkins LR, Maier SF. The danger-associated molecular pattern HMGB1 mediates the neuroinflammatory effects of methamphetamine. Brain, Behavior, and Immunity. PMID 26254235 DOI: 10.1016/J.Bbi.2015.08.001 |
0.533 |
|
| 2015 |
Frank MG, Watkins LR, Maier SF. The permissive role of glucocorticoids in neuroinflammatory priming: mechanisms and insights. Current Opinion in Endocrinology, Diabetes, and Obesity. 22: 300-5. PMID 26087336 DOI: 10.1097/MED.0000000000000168 |
0.468 |
|
| 2015 |
Bachtell R, Hutchinson MR, Wang X, Rice KC, Maier SF, Watkins LR. Targeting the Toll of Drug Abuse: The Translational Potential of Toll-Like Receptor 4. Cns & Neurological Disorders Drug Targets. 14: 692-9. PMID 26022268 DOI: 10.2174/1871527314666150529132503 |
0.762 |
|
| 2015 |
Selfridge BR, Wang X, Zhang Y, Yin H, Grace PM, Watkins LR, Jacobson AE, Rice KC. Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists. Journal of Medicinal Chemistry. 58: 5038-52. PMID 26010811 DOI: 10.1021/Acs.Jmedchem.5B00426 |
0.815 |
|
| 2015 |
Grace PM, Maier SF, Watkins LR. Opioid-induced central immune signaling: implications for opioid analgesia. Headache. 55: 475-89. PMID 25833219 DOI: 10.1111/Head.12552 |
0.809 |
|
| 2015 |
Frank MG, Weber MD, Watkins LR, Maier SF. Stress sounds the alarmin: The role of the danger-associated molecular pattern HMGB1 in stress-induced neuroinflammatory priming. Brain, Behavior, and Immunity. 48: 1-7. PMID 25816800 DOI: 10.1016/j.bbi.2015.03.010 |
0.535 |
|
| 2015 |
Grace PM, Shimizu K, Strand KA, Rice KC, Deng G, Watkins LR, Herson PS. (+)-Naltrexone is neuroprotective and promotes alternative activation in the mouse hippocampus after cardiac arrest/cardiopulmonary resuscitation. Brain, Behavior, and Immunity. 48: 115-22. PMID 25774010 DOI: 10.1016/J.Bbi.2015.03.005 |
0.735 |
|
| 2015 |
Barrientos RM, Kitt MM, Watkins LR, Maier SF. Neuroinflammation in the normal aging hippocampus. Neuroscience. PMID 25772789 DOI: 10.1016/j.neuroscience.2015.03.007 |
0.486 |
|
| 2015 |
Loram LC, Strand KA, Taylor FR, Sloane E, Van Dam AM, Rieger J, Maier SF, Watkins LR. Adenosine 2A receptor agonism: A single intrathecal administration attenuates motor paralysis in experimental autoimmune encephalopathy in rats. Brain, Behavior, and Immunity. 46: 50-4. PMID 25653191 DOI: 10.1016/J.Bbi.2015.01.014 |
0.765 |
|
| 2015 |
Northcutt AL, Hutchinson MR, Wang X, Baratta MV, Hiranita T, Cochran TA, Pomrenze MB, Galer EL, Kopajtic TA, Li CM, Amat J, Larson G, Cooper DC, Huang Y, O'Neill CE, ... ... Watkins LR, et al. DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling. Molecular Psychiatry. PMID 25644383 DOI: 10.1038/Mp.2014.177 |
0.769 |
|
| 2015 |
Griggs RB, Donahue RR, Morgenweck J, Grace PM, Sutton A, Watkins LR, Taylor BK. Pioglitazone rapidly reduces neuropathic pain through astrocyte and nongenomic PPARγ mechanisms. Pain. 156: 469-82. PMID 25599238 DOI: 10.1097/01.J.Pain.0000460333.79127.Be |
0.793 |
|
| 2015 |
Weber MD, Frank MG, Tracey KJ, Watkins LR, Maier SF. Stress induces the danger-associated molecular pattern HMGB-1 in the hippocampus of male Sprague Dawley rats: a priming stimulus of microglia and the NLRP3 inflammasome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 316-24. PMID 25568124 DOI: 10.1523/JNEUROSCI.3561-14.2015 |
0.544 |
|
| 2015 |
Barrientos RM, Thompson VM, Kitt MM, Amat J, Hale MW, Frank MG, Crysdale NY, Stamper CE, Hennessey PA, Watkins LR, Spencer RL, Lowry CA, Maier SF. Greater glucocorticoid receptor activation in hippocampus of aged rats sensitizes microglia. Neurobiology of Aging. 36: 1483-95. PMID 25559333 DOI: 10.1016/J.Neurobiolaging.2014.12.003 |
0.49 |
|
| 2015 |
Corrigan F, Wu Y, Tuke J, Coller JK, Rice KC, Diener KR, Hayball JD, Watkins LR, Somogyi AA, Hutchinson MR. Alcohol-induced sedation and synergistic interactions between alcohol and morphine: a key mechanistic role for Toll-like receptors and MyD88-dependent signaling. Brain, Behavior, and Immunity. 45: 245-52. PMID 25542736 DOI: 10.1016/J.Bbi.2014.12.019 |
0.765 |
|
| 2015 |
Kwilasz AJ, Grace PM, Serbedzija P, Maier SF, Watkins LR. The therapeutic potential of interleukin-10 in neuroimmune diseases. Neuropharmacology. 96: 55-69. PMID 25446571 DOI: 10.1016/J.Neuropharm.2014.10.020 |
0.786 |
|
| 2015 |
Fonken LK, Frank MG, Kitt MM, Barrientos RM, Watkins LR, Maier SF. Microglia inflammatory responses are controlled by an intrinsic circadian clock. Brain, Behavior, and Immunity. 45: 171-9. PMID 25433170 DOI: 10.1016/J.Bbi.2014.11.009 |
0.51 |
|
| 2015 |
Lewis SS, Hutchinson MR, Frick MM, Zhang Y, Maier SF, Sammakia T, Rice KC, Watkins LR. Select steroid hormone glucuronide metabolites can cause toll-like receptor 4 activation and enhanced pain. Brain, Behavior, and Immunity. 44: 128-36. PMID 25218902 DOI: 10.1016/J.Bbi.2014.09.004 |
0.833 |
|
| 2015 |
Barrientos RM, Thompson VM, Arnold TH, Frank MG, Watkins LR, Maier SF. The role of hepatic and splenic macrophages in E. coli-induced memory impairments in aged rats. Brain, Behavior, and Immunity. 43: 60-7. PMID 25043992 DOI: 10.1016/j.bbi.2014.07.004 |
0.471 |
|
| 2015 |
Frank MG, Weber MD, Watkins LR, Maier SF. Stress-induced neuroinflammatory priming: A liability factor in the etiology of psychiatric disorders Neurobiology of Stress. DOI: 10.1016/j.ynstr.2015.12.004 |
0.345 |
|
| 2015 |
Grace P, Wang X, Urban D, Baratta M, Galer E, Strand K, Zhang Y, Yin H, Roth B, Maier S, Watkins L. (250) Selective manipulation of spinal microglia by chemogenetics: implications for allodynia and inflammatory signaling The Journal of Pain. 16: S38. DOI: 10.1016/J.Jpain.2015.01.167 |
0.795 |
|
| 2015 |
Barrientos R, Kitt M, Thompson V, Watkins L, Maier S. The interaction effects of surgery and morphine treatment on neuroinflammation and cognitive function in aged rats Brain, Behavior, and Immunity. 49: e41. DOI: 10.1016/j.bbi.2015.06.155 |
0.513 |
|
| 2015 |
Fonken L, Kitt M, Watkins L, Barrientos R, Maier S. Diminished circadian rhythms in microglia may contribute to age-related neuroinflammatory sensitization Brain, Behavior, and Immunity. 49: e23. DOI: 10.1016/J.Bbi.2015.06.098 |
0.471 |
|
| 2015 |
Grace P, Wang X, Urban D, Baratta M, Galer E, Strand K, Zhang Y, Yin H, Roth B, Maier S, Watkins L. Selective manipulation of spinal microglia by chemogenetics: Implications for allodynia and inflammatory signaling Brain, Behavior, and Immunity. 49: e7. DOI: 10.1016/J.Bbi.2015.06.045 |
0.826 |
|
| 2015 |
Bachtell R, Hutchinson MR, Wang X, Rice KC, Maier SF, Watkins LR. Targeting the toll of drug abuse: The translational potential of toll-like receptor 4 Cns and Neurological Disorders - Drug Targets. 14: 692-698. |
0.715 |
|
| 2014 |
Christianson JP, Flyer-Adams JG, Drugan RC, Amat J, Daut RA, Foilb AR, Watkins LR, Maier SF. Learned stressor resistance requires extracellular signal-regulated kinase in the prefrontal cortex. Frontiers in Behavioral Neuroscience. 8: 348. PMID 25324750 DOI: 10.3389/Fnbeh.2014.00348 |
0.502 |
|
| 2014 |
Grace PM, Ramos KM, Rodgers KM, Wang X, Hutchinson MR, Lewis MT, Morgan KN, Kroll JL, Taylor FR, Strand KA, Zhang Y, Berkelhammer D, Huey MG, Greene LI, Cochran TA, ... ... Watkins LR, et al. Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelae. Neuroscience. 280: 299-317. PMID 25241065 DOI: 10.1016/J.Neuroscience.2014.09.020 |
0.82 |
|
| 2014 |
Jacobsen JH, Watkins LR, Hutchinson MR. Discovery of a novel site of opioid action at the innate immune pattern-recognition receptor TLR4 and its role in addiction. International Review of Neurobiology. 118: 129-63. PMID 25175864 DOI: 10.1016/B978-0-12-801284-0.00006-3 |
0.757 |
|
| 2014 |
Watkins LR, Wang X, Mustafa S, Hutchinson MR. In vivo veritas: (+)-Naltrexone's actions define translational importance: A letter in response to Skolnick et al. 'Translational potential of naloxone and naltrexone as TLR4 antagonists'. Trends in Pharmacological Sciences. 35: 432-3. PMID 25109571 DOI: 10.1016/J.Tips.2014.07.002 |
0.741 |
|
| 2014 |
Zwicker JD, Zhang Y, Ren J, Hutchinson MR, Rice KC, Watkins LR, Greer JJ, Funk GD. Glial TLR4 signaling does not contribute to opioid-induced depression of respiration. Journal of Applied Physiology (Bethesda, Md. : 1985). 117: 857-68. PMID 25103966 DOI: 10.1152/Japplphysiol.00534.2014 |
0.74 |
|
| 2014 |
Sobesky JL, Barrientos RM, De May HS, Thompson BM, Weber MD, Watkins LR, Maier SF. High-fat diet consumption disrupts memory and primes elevations in hippocampal IL-1β, an effect that can be prevented with dietary reversal or IL-1 receptor antagonism. Brain, Behavior, and Immunity. 42: 22-32. PMID 24998196 DOI: 10.1016/J.Bbi.2014.06.017 |
0.471 |
|
| 2014 |
Amat J, Christianson JP, Aleksejev RM, Kim J, Richeson KR, Watkins LR, Maier SF. Control over a stressor involves the posterior dorsal striatum and the act/outcome circuit. The European Journal of Neuroscience. 40: 2352-8. PMID 24862585 DOI: 10.1111/Ejn.12609 |
0.466 |
|
| 2014 |
Watkins LR, Hutchinson MR. A concern on comparing 'apples' and 'oranges' when differences between microglia used in human and rodent studies go far, far beyond simply species: comment on Smith and Dragunow. Trends in Neurosciences. 37: 189-90. PMID 24612510 DOI: 10.1016/j.tins.2014.02.004 |
0.68 |
|
| 2014 |
Grace PM, Hutchinson MR, Maier SF, Watkins LR. Pathological pain and the neuroimmune interface. Nature Reviews. Immunology. 14: 217-31. PMID 24577438 DOI: 10.1038/Nri3621 |
0.824 |
|
| 2014 |
Frank MG, Hershman SA, Weber MD, Watkins LR, Maier SF. Chronic exposure to exogenous glucocorticoids primes microglia to pro-inflammatory stimuli and induces NLRP3 mRNA in the hippocampus. Psychoneuroendocrinology. 40: 191-200. PMID 24485491 DOI: 10.1016/j.psyneuen.2013.11.006 |
0.525 |
|
| 2014 |
Ellis A, Wieseler J, Favret J, Johnson KW, Rice KC, Maier SF, Falci S, Watkins LR. Systemic administration of propentofylline, ibudilast, and (+)-naltrexone each reverses mechanical allodynia in a novel rat model of central neuropathic pain. The Journal of Pain : Official Journal of the American Pain Society. 15: 407-21. PMID 24412802 DOI: 10.1016/J.Jpain.2013.12.007 |
0.783 |
|
| 2014 |
Grace PM, Strand KA, Maier SF, Watkins LR. Suppression of voluntary wheel running in rats is dependent on the site of inflammation: evidence for voluntary running as a measure of hind paw-evoked pain. The Journal of Pain : Official Journal of the American Pain Society. 15: 121-8. PMID 24287315 DOI: 10.1016/J.Jpain.2013.10.001 |
0.812 |
|
| 2014 |
Hutchinson MR, Watkins LR. Why is neuroimmunopharmacology crucial for the future of addiction research? Neuropharmacology. 76: 218-27. PMID 23764149 DOI: 10.1016/j.neuropharm.2013.05.039 |
0.725 |
|
| 2014 |
Grace P, Strand K, Galer E, Zhang Y, Greene L, Rice K, Maier S, Watkins L. (299) Therapeutic morphine prolongs neuropathic pain in Fischer 344 rats: a role for TLR4 and inflammasome signaling in the lumbar spinal cord The Journal of Pain. 15: S50. DOI: 10.1016/J.Jpain.2014.01.209 |
0.819 |
|
| 2014 |
Grace P, Strand K, Galer E, Zhang Y, Berkelhammer D, Greene L, Rice K, Maier S, Watkins L. 31. Therapeutic morphine prolongs neuropathic pain in rats: A role for TLR4 and inflammasome signaling in the lumbar spinal cord Brain, Behavior, and Immunity. 40: e9-e10. DOI: 10.1016/J.Bbi.2014.06.051 |
0.801 |
|
| 2013 |
Loram LC, Taylor FR, Strand KA, Harrison JA, Rzasalynn R, Sholar P, Rieger J, Maier SF, Watkins LR. Intrathecal injection of adenosine 2A receptor agonists reversed neuropathic allodynia through protein kinase (PK)A/PKC signaling. Brain, Behavior, and Immunity. 33: 112-22. PMID 23811314 DOI: 10.1016/j.bbi.2013.06.004 |
0.596 |
|
| 2013 |
Wang X, Grace PM, Pham MN, Cheng K, Strand KA, Smith C, Li J, Watkins LR, Yin H. Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2713-22. PMID 23568774 DOI: 10.1096/Fj.12-222992 |
0.821 |
|
| 2013 |
Bastos LF, Godin AM, Zhang Y, Jarussophon S, Ferreira BC, Machado RR, Maier SF, Konishi Y, de Freitas RP, Fiebich BL, Watkins LR, Coelho MM, Moraes MF. A minocycline derivative reduces nerve injury-induced allodynia, LPS-induced prostaglandin E2 microglial production and signaling via toll-like receptors 2 and 4. Neuroscience Letters. 543: 157-62. PMID 23523650 DOI: 10.1016/J.Neulet.2013.03.014 |
0.583 |
|
| 2013 |
Weber MD, Frank MG, Sobesky JL, Watkins LR, Maier SF. Blocking toll-like receptor 2 and 4 signaling during a stressor prevents stress-induced priming of neuroinflammatory responses to a subsequent immune challenge. Brain, Behavior, and Immunity. 32: 112-21. PMID 23500798 DOI: 10.1016/j.bbi.2013.03.004 |
0.532 |
|
| 2013 |
Frank MG, Watkins LR, Maier SF. Stress-induced glucocorticoids as a neuroendocrine alarm signal of danger. Brain, Behavior, and Immunity. 33: 1-6. PMID 23459026 DOI: 10.1016/j.bbi.2013.02.004 |
0.511 |
|
| 2013 |
Theberge FR, Li X, Kambhampati S, Pickens CL, St Laurent R, Bossert JM, Baumann MH, Hutchinson MR, Rice KC, Watkins LR, Shaham Y. Effect of chronic delivery of the Toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin craving. Biological Psychiatry. 73: 729-37. PMID 23384483 DOI: 10.1016/J.Biopsych.2012.12.019 |
0.723 |
|
| 2013 |
Christianson JP, Drugan RC, Flyer JG, Watkins LR, Maier SF. Anxiogenic effects of brief swim stress are sensitive to stress history. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 44: 17-22. PMID 23357538 DOI: 10.1016/J.Pnpbp.2013.01.011 |
0.495 |
|
| 2013 |
Lewis SS, Hutchinson MR, Zhang Y, Hund DK, Maier SF, Rice KC, Watkins LR. Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain. Brain, Behavior, and Immunity. 30: 24-32. PMID 23348028 DOI: 10.1016/J.Bbi.2013.01.005 |
0.824 |
|
| 2013 |
Barrientos R, Arnold T, Loram L, Frank M, Crysdale N, Watkins L, Maier S. 55. The role of the liver in E. coli-induced memory impairments in aged rats Brain, Behavior, and Immunity. 32: e16. DOI: 10.1016/j.bbi.2013.07.067 |
0.505 |
|
| 2013 |
Grace P, Greene L, Strand K, Rice K, Maier S, Watkins L. 18. Repeated morphine enhances peripheral nerve injury-induced allodynia via central immune mechanisms Brain, Behavior, and Immunity. 32: e5-e6. DOI: 10.1016/J.Bbi.2013.07.030 |
0.772 |
|
| 2012 |
Loram LC, Taylor FR, Strand KA, Maier SF, Speake JD, Jordan KG, James JW, Wene SP, Pritchard RC, Green H, Van Dyke K, Mazarov A, Letchworth SR, Watkins LR. Systemic administration of an alpha-7 nicotinic acetylcholine agonist reverses neuropathic pain in male Sprague Dawley rats. The Journal of Pain : Official Journal of the American Pain Society. 13: 1162-71. PMID 23182225 DOI: 10.1016/j.jpain.2012.08.009 |
0.589 |
|
| 2012 |
Wang X, Fiorini Z, Smith C, Zhang Y, Li J, Watkins LR, Yin H. Repositioning antimicrobial agent pentamidine as a disruptor of the lateral interactions of transmembrane domain 5 of EBV latent membrane protein 1. Plos One. 7: e47703. PMID 23094078 DOI: 10.1371/Journal.Pone.0047703 |
0.494 |
|
| 2012 |
Barrientos RM, Hein AM, Frank MG, Watkins LR, Maier SF. Intracisternal interleukin-1 receptor antagonist prevents postoperative cognitive decline and neuroinflammatory response in aged rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14641-8. PMID 23077050 DOI: 10.1523/Jneurosci.2173-12.2012 |
0.498 |
|
| 2012 |
Loram LC, Grace PM, Strand KA, Taylor FR, Ellis A, Berkelhammer D, Bowlin M, Skarda B, Maier SF, Watkins LR. Prior exposure to repeated morphine potentiates mechanical allodynia induced by peripheral inflammation and neuropathy. Brain, Behavior, and Immunity. 26: 1256-64. PMID 22902523 DOI: 10.1016/J.Bbi.2012.08.003 |
0.838 |
|
| 2012 |
Hutchinson MR, Northcutt AL, Hiranita T, Wang X, Lewis SS, Thomas J, van Steeg K, Kopajtic TA, Loram LC, Sfregola C, Galer E, Miles NE, Bland ST, Amat J, Rozeske RR, ... ... Watkins LR, et al. Opioid activation of toll-like receptor 4 contributes to drug reinforcement. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11187-200. PMID 22895704 DOI: 10.1523/Jneurosci.0684-12.2012 |
0.811 |
|
| 2012 |
Frank MG, Barrientos RM, Thompson BM, Weber MD, Watkins LR, Maier SF. IL-1RA injected intra-cisterna magna confers extended prophylaxis against lipopolysaccharide-induced neuroinflammatory and sickness responses. Journal of Neuroimmunology. 252: 33-9. PMID 22871632 DOI: 10.1016/J.Jneuroim.2012.07.010 |
0.47 |
|
| 2012 |
Kubala KH, Christianson JP, Kaufman RD, Watkins LR, Maier SF. Short- and long-term consequences of stressor controllability in adolescent rats. Behavioural Brain Research. 234: 278-84. PMID 22771417 DOI: 10.1016/J.Bbr.2012.06.027 |
0.447 |
|
| 2012 |
Grace PM, Hurley D, Barratt DT, Tsykin A, Watkins LR, Rolan PE, Hutchinson MR. Harnessing pain heterogeneity and RNA transcriptome to identify blood-based pain biomarkers: a novel correlational study design and bioinformatics approach in a graded chronic constriction injury model. Journal of Neurochemistry. 122: 976-94. PMID 22697386 DOI: 10.1111/J.1471-4159.2012.07833.X |
0.815 |
|
| 2012 |
Helmreich DL, Tylee D, Christianson JP, Kubala KH, Govindarajan ST, O'Neill WE, Becoats K, Watkins L, Maier SF. Active behavioral coping alters the behavioral but not the endocrine response to stress. Psychoneuroendocrinology. 37: 1941-8. PMID 22578266 DOI: 10.1016/J.Psyneuen.2012.04.005 |
0.471 |
|
| 2012 |
Hughes JP, Chessell I, Malamut R, Perkins M, BaÄkonja M, Baron R, Farrar JT, Field MJ, Gereau RW, Gilron I, McMahon SB, Porreca F, Rappaport BA, Rice F, Richman LK, ... ... Watkins LR, et al. Understanding chronic inflammatory and neuropathic pain. Annals of the New York Academy of Sciences. 1255: 30-44. PMID 22564068 DOI: 10.1111/J.1749-6632.2012.06561.X |
0.399 |
|
| 2012 |
Lewis SS, Loram LC, Hutchinson MR, Li CM, Zhang Y, Maier SF, Huang Y, Rice KC, Watkins LR. (+)-naloxone, an opioid-inactive toll-like receptor 4 signaling inhibitor, reverses multiple models of chronic neuropathic pain in rats. The Journal of Pain : Official Journal of the American Pain Society. 13: 498-506. PMID 22520687 DOI: 10.1016/J.Jpain.2012.02.005 |
0.844 |
|
| 2012 |
Loram LC, Sholar PW, Taylor FR, Wiesler JL, Babb JA, Strand KA, Berkelhammer D, Day HE, Maier SF, Watkins LR. Sex and estradiol influence glial pro-inflammatory responses to lipopolysaccharide in rats. Psychoneuroendocrinology. 37: 1688-99. PMID 22497984 DOI: 10.1016/J.Psyneuen.2012.02.018 |
0.489 |
|
| 2012 |
Wang X, Loram LC, Ramos K, de Jesus AJ, Thomas J, Cheng K, Reddy A, Somogyi AA, Hutchinson MR, Watkins LR, Yin H. Morphine activates neuroinflammation in a manner parallel to endotoxin. Proceedings of the National Academy of Sciences of the United States of America. 109: 6325-30. PMID 22474354 DOI: 10.1073/Pnas.1200130109 |
0.812 |
|
| 2012 |
Barrientos RM, Frank MG, Watkins LR, Maier SF. Aging-related changes in neuroimmune-endocrine function: implications for hippocampal-dependent cognition. Hormones and Behavior. 62: 219-27. PMID 22370243 DOI: 10.1016/j.yhbeh.2012.02.010 |
0.475 |
|
| 2012 |
Wieseler J, Ellis A, Maier SF, Watkins LR, Falci S. Unilateral T13 and L1 dorsal root avulsion: methods for a novel model of central neuropathic pain. Methods in Molecular Biology (Clifton, N.J.). 851: 171-83. PMID 22351090 DOI: 10.1007/978-1-61779-561-9_12 |
0.761 |
|
| 2012 |
Wieseler J, Sprunger D, Ellis A, Maier SF, Watkins LR. Indwelling supradural catheters for induction of facial allodynia: surgical procedures, application of inflammatory stimuli, and behavioral testing. Methods in Molecular Biology (Clifton, N.J.). 851: 99-107. PMID 22351084 DOI: 10.1007/978-1-61779-561-9_6 |
0.76 |
|
| 2012 |
Bastos LF, de Oliveira AC, Watkins LR, Moraes MF, Coelho MM. Tetracyclines and pain. Naunyn-Schmiedeberg's Archives of Pharmacology. 385: 225-41. PMID 22282331 DOI: 10.1007/S00210-012-0727-1 |
0.367 |
|
| 2012 |
Watkins LR, Hutchinson MR, Johnson KW. Commentary on Landry et al.: "Propentofylline, a CNS glial modulator, does not decrease pain in post-herpetic neuralgia patients: in vitro evidence for differential responses in human and rodent microglia and macrophages". Experimental Neurology. 234: 351-3. PMID 22269389 DOI: 10.1016/j.expneurol.2012.01.006 |
0.726 |
|
| 2012 |
Bastos LF, Medeiros DC, Vieira RP, Watkins LR, Coelho MM, Moraes MF. Intraneural dexamethasone applied simultaneously to rat sciatic nerve constriction delays the development of hyperalgesia and allodynia. Neuroscience Letters. 510: 20-3. PMID 22240103 DOI: 10.1016/J.Neulet.2011.12.062 |
0.441 |
|
| 2012 |
Rozeske RR, Der-Avakian A, Watkins LR, Maier SF. Activation of the medial prefrontal cortex by escapable stress is necessary for protection against subsequent inescapable stress-induced potentiation of morphine conditioned place preference. The European Journal of Neuroscience. 35: 160-5. PMID 22118376 DOI: 10.1111/J.1460-9568.2011.07929.X |
0.528 |
|
| 2012 |
Frank MG, Thompson BM, Watkins LR, Maier SF. Glucocorticoids mediate stress-induced priming of microglial pro-inflammatory responses. Brain, Behavior, and Immunity. 26: 337-45. PMID 22041296 DOI: 10.1016/J.Bbi.2011.10.005 |
0.528 |
|
| 2012 |
Nicotra L, Loram LC, Watkins LR, Hutchinson MR. Toll-like receptors in chronic pain. Experimental Neurology. 234: 316-29. PMID 22001158 DOI: 10.1016/J.Expneurol.2011.09.038 |
0.824 |
|
| 2012 |
Wu Y, Lousberg EL, Moldenhauer LM, Hayball JD, Coller JK, Rice KC, Watkins LR, Somogyi AA, Hutchinson MR. Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice. British Journal of Pharmacology. 165: 1319-29. PMID 21955045 DOI: 10.1111/J.1476-5381.2011.01572.X |
0.747 |
|
| 2012 |
Johnston IN, Maier SF, Rudy JW, Watkins LR. Post-conditioning experience with acute or chronic inflammatory pain reduces contextual fear conditioning in the rat. Behavioural Brain Research. 226: 361-8. PMID 21920390 DOI: 10.1016/j.bbr.2011.08.048 |
0.556 |
|
| 2012 |
Barrientos R, Crysdale N, Hale M, Amat J, Frank M, Stamper C, Hennessey P, Watkins L, Spencer R, Lowry C, Maier S. 170. Characterization of the neuroendocrine system in healthy aged rats Brain, Behavior, and Immunity. 26: S47. DOI: 10.1016/J.Bbi.2012.07.194 |
0.482 |
|
| 2011 |
Rozeske RR, Evans AK, Frank MG, Watkins LR, Lowry CA, Maier SF. Uncontrollable, but not controllable, stress desensitizes 5-HT1A receptors in the dorsal raphe nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14107-15. PMID 21976495 DOI: 10.1523/Jneurosci.3095-11.2011 |
0.463 |
|
| 2011 |
Hains LE, Loram LC, Taylor FR, Strand KA, Wieseler JL, Barrientos RM, Young JJ, Frank MG, Sobesky J, Martin TJ, Eisenach JC, Maier SF, Johnson JD, Fleshner M, Watkins LR. Prior laparotomy or corticosterone potentiates lipopolysaccharide-induced fever and sickness behaviors. Journal of Neuroimmunology. 239: 53-60. PMID 21907418 DOI: 10.1016/j.jneuroim.2011.08.011 |
0.58 |
|
| 2011 |
Barrientos RM, Frank MG, Crysdale NY, Chapman TR, Ahrendsen JT, Day HE, Campeau S, Watkins LR, Patterson SL, Maier SF. Little exercise, big effects: reversing aging and infection-induced memory deficits, and underlying processes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11578-86. PMID 21832188 DOI: 10.1523/Jneurosci.2266-11.2011 |
0.456 |
|
| 2011 |
Hutchinson MR, Shavit Y, Grace PM, Rice KC, Maier SF, Watkins LR. Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia. Pharmacological Reviews. 63: 772-810. PMID 21752874 DOI: 10.1124/Pr.110.004135 |
0.827 |
|
| 2011 |
Christianson JP, Jennings JH, Ragole T, Flyer JG, Benison AM, Barth DS, Watkins LR, Maier SF. Safety signals mitigate the consequences of uncontrollable stress via a circuit involving the sensory insular cortex and bed nucleus of the stria terminalis. Biological Psychiatry. 70: 458-64. PMID 21684526 DOI: 10.1016/J.Biopsych.2011.04.004 |
0.468 |
|
| 2011 |
Liu L, Ghosh N, Slivka PF, Fiorini Z, Hutchinson MR, Watkins LR, Yin H. An MD2 hot-spot-mimicking peptide that suppresses TLR4-mediated inflammatory response in vitro and in vivo. Chembiochem : a European Journal of Chemical Biology. 12: 1827-31. PMID 21678541 DOI: 10.1002/Cbic.201100211 |
0.767 |
|
| 2011 |
Loram LC, Taylor FR, Strand KA, Frank MG, Sholar P, Harrison JA, Maier SF, Watkins LR. Prior exposure to glucocorticoids potentiates lipopolysaccharide induced mechanical allodynia and spinal neuroinflammation. Brain, Behavior, and Immunity. 25: 1408-15. PMID 21536123 DOI: 10.1016/j.bbi.2011.04.013 |
0.615 |
|
| 2011 |
Benison AM, Chumachenko S, Harrison JA, Maier SF, Falci SP, Watkins LR, Barth DS. Caudal granular insular cortex is sufficient and necessary for the long-term maintenance of allodynic behavior in the rat attributable to mononeuropathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6317-28. PMID 21525272 DOI: 10.1523/Jneurosci.0076-11.2011 |
0.553 |
|
| 2011 |
Liu L, Coller JK, Watkins LR, Somogyi AA, Hutchinson MR. Naloxone-precipitated morphine withdrawal behavior and brain IL-1β expression: comparison of different mouse strains. Brain, Behavior, and Immunity. 25: 1223-32. PMID 21447380 DOI: 10.1016/j.bbi.2011.03.016 |
0.781 |
|
| 2011 |
Wu Y, Lousberg EL, Moldenhauer LM, Hayball JD, Robertson SA, Coller JK, Watkins LR, Somogyi AA, Hutchinson MR. Attenuation of microglial and IL-1 signaling protects mice from acute alcohol-induced sedation and/or motor impairment. Brain, Behavior, and Immunity. 25: S155-64. PMID 21276848 DOI: 10.1016/j.bbi.2011.01.012 |
0.744 |
|
| 2011 |
Rozeske RR, Greenwood BN, Fleshner M, Watkins LR, Maier SF. Voluntary wheel running produces resistance to inescapable stress-induced potentiation of morphine conditioned place preference. Behavioural Brain Research. 219: 378-81. PMID 21262267 DOI: 10.1016/J.Bbr.2011.01.030 |
0.484 |
|
| 2011 |
Frank MG, Watkins LR, Maier SF. Stress- and glucocorticoid-induced priming of neuroinflammatory responses: potential mechanisms of stress-induced vulnerability to drugs of abuse. Brain, Behavior, and Immunity. 25: S21-8. PMID 21256955 DOI: 10.1016/j.bbi.2011.01.005 |
0.498 |
|
| 2011 |
Sumracki NM, Nicotra L, Kwok YH, Liu L, Van Steeg K, R.Watkins L, Hutchinson MR. The future: New concepts and potential therapies Neuropathic Pain: Causes, Management, and Understanding. 341-356. DOI: 10.1017/CBO9781139152211.030 |
0.754 |
|
| 2011 |
Barrientos R, Crysdale N, Amat J, Frank M, Watkins L, Maier S. 218. Elevated hippocampal corticosterone levels may be responsible for sensitizing microglia of healthy aged rats Brain, Behavior, and Immunity. 25: S241-S242. DOI: 10.1016/j.bbi.2011.07.221 |
0.455 |
|
| 2011 |
Watkins L, Northcutt A, Loram L, Lewis S, Hutchinson M, Rice K, Maier S. 210. Rethinking CNS innate immune responses: Sex, pain and drugs of abuse Brain, Behavior, and Immunity. 25: S239. DOI: 10.1016/J.Bbi.2011.07.213 |
0.808 |
|
| 2011 |
Hutchinson M, Wu Y, Jaehne E, Liu L, Diener K, Hayball J, Rice K, Watkins L, Somogyi A. 97. Contributions of innate immune signaling to opioid & alcohol responses Brain, Behavior, and Immunity. 25: S206-S207. DOI: 10.1016/J.Bbi.2011.07.100 |
0.753 |
|
| 2011 |
Northcutt A, Stregola C, Bland S, Amat J, Hutchinson M, Miles N, Rosezke R, Loeffler M, Maier S, Rice K, Watkins L. Novel toll like receptor 4 (TLR4) involvement in drug reward Brain Behavior and Immunity. 25. DOI: 10.1016/J.Bbi.2011.07.040 |
0.784 |
|
| 2011 |
Liu L, Ghosh N, Slivka PF, Fiorini Z, Hutchinson MR, Watkins LR, Yin H. Inside Cover: An MD2 Hot-Spot-Mimicking Peptide that Suppresses TLR4-Mediated Inflammatory Response in vitro and in vivo (ChemBioChem 12/2011) Chembiochem. 12: 1786-1786. DOI: 10.1002/Cbic.201190054 |
0.755 |
|
| 2010 |
Barrientos RM, Frank MG, Watkins LR, Maier SF. Memory impairments in healthy aging: Role of aging-induced microglial sensitization. Aging and Disease. 1: 212-231. PMID 21132050 |
0.395 |
|
| 2010 |
Muscoli C, Doyle T, Dagostino C, Bryant L, Chen Z, Watkins LR, Ryerse J, Bieberich E, Neumman W, Salvemini D. Counter-regulation of opioid analgesia by glial-derived bioactive sphingolipids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15400-8. PMID 21084596 DOI: 10.1523/Jneurosci.2391-10.2010 |
0.43 |
|
| 2010 |
Thompson BM, Baratta MV, Biedenkapp JC, Rudy JW, Watkins LR, Maier SF. Activation of the infralimbic cortex in a fear context enhances extinction learning. Learning & Memory (Cold Spring Harbor, N.Y.). 17: 591-9. PMID 21041382 DOI: 10.1101/Lm.1920810 |
0.479 |
|
| 2010 |
Bevan DE, Martinko AJ, Loram LC, Stahl JA, Taylor FR, Joshee S, Watkins LR, Yin H. Selection, Preparation, and Evaluation of Small- Molecule Inhibitors of Toll-Like Receptor 4. Acs Medicinal Chemistry Letters. 1: 194-198. PMID 20824192 DOI: 10.1021/Ml100041F |
0.578 |
|
| 2010 |
Maier SF, Watkins LR. Role of the medial prefrontal cortex in coping and resilience. Brain Research. 1355: 52-60. PMID 20727864 DOI: 10.1016/j.brainres.2010.08.039 |
0.459 |
|
| 2010 |
Joce C, Stahl JA, Shridhar M, Hutchinson MR, Watkins LR, Fedichev PO, Yin H. Application of a novel in silico high-throughput screen to identify selective inhibitors for protein-protein interactions. Bioorganic & Medicinal Chemistry Letters. 20: 5411-3. PMID 20709548 DOI: 10.1016/J.Bmcl.2010.07.103 |
0.728 |
|
| 2010 |
Wieseler J, Ellis AL, McFadden A, Brown K, Starnes C, Maier SF, Watkins LR, Falci S. Below level central pain induced by discrete dorsal spinal cord injury. Journal of Neurotrauma. 27: 1697-707. PMID 20649467 DOI: 10.1089/Neu.2010.1311 |
0.763 |
|
| 2010 |
Ramos KM, Lewis MT, Morgan KN, Crysdale NY, Kroll JL, Taylor FR, Harrison JA, Sloane EM, Maier SF, Watkins LR. Spinal upregulation of glutamate transporter GLT-1 by ceftriaxone: therapeutic efficacy in a range of experimental nervous system disorders. Neuroscience. 169: 1888-900. PMID 20547213 DOI: 10.1016/J.Neuroscience.2010.06.014 |
0.805 |
|
| 2010 |
Frank MG, Barrientos RM, Watkins LR, Maier SF. Aging sensitizes rapidly isolated hippocampal microglia to LPS ex vivo. Journal of Neuroimmunology. 226: 181-4. PMID 20537730 DOI: 10.1016/j.jneuroim.2010.05.022 |
0.497 |
|
| 2010 |
Hains LE, Loram LC, Weiseler JL, Frank MG, Bloss EB, Sholar P, Taylor FR, Harrison JA, Martin TJ, Eisenach JC, Maier SF, Watkins LR. Pain intensity and duration can be enhanced by prior challenge: initial evidence suggestive of a role of microglial priming. The Journal of Pain : Official Journal of the American Pain Society. 11: 1004-14. PMID 20434956 DOI: 10.1016/j.jpain.2010.01.271 |
0.786 |
|
| 2010 |
Buchanan MM, Hutchinson M, Watkins LR, Yin H. Toll-like receptor 4 in CNS pathologies. Journal of Neurochemistry. 114: 13-27. PMID 20402965 DOI: 10.1111/J.1471-4159.2010.06736.X |
0.776 |
|
| 2010 |
Hutchinson MR, Loram LC, Zhang Y, Shridhar M, Rezvani N, Berkelhammer D, Phipps S, Foster PS, Landgraf K, Falke JJ, Rice KC, Maier SF, Yin H, Watkins LR. Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity. Neuroscience. 168: 551-63. PMID 20381591 DOI: 10.1016/J.Neuroscience.2010.03.067 |
0.818 |
|
| 2010 |
Loram LC, Harrison JA, Chao L, Taylor FR, Reddy A, Travis CL, Giffard R, Al-Abed Y, Tracey K, Maier SF, Watkins LR. Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats. Brain, Behavior, and Immunity. 24: 959-67. PMID 20353818 DOI: 10.1016/J.Bbi.2010.03.008 |
0.578 |
|
| 2010 |
Soderquist RG, Sloane EM, Loram LC, Harrison JA, Dengler EC, Johnson SM, Amer LD, Young CS, Lewis MT, Poole S, Frank MG, Watkins LR, Milligan ED, Mahoney MJ. Release of plasmid DNA-encoding IL-10 from PLGA microparticles facilitates long-term reversal of neuropathic pain following a single intrathecal administration. Pharmaceutical Research. 27: 841-54. PMID 20224990 DOI: 10.1007/S11095-010-0077-Y |
0.809 |
|
| 2010 |
Bland ST, Beckley JT, Watkins LR, Maier SF, Bilbo SD. Neonatal Escherichia coli infection alters glial, cytokine, and neuronal gene expression in response to acute amphetamine in adolescent rats. Neuroscience Letters. 474: 52-7. PMID 20223277 DOI: 10.1016/J.Neulet.2010.03.006 |
0.501 |
|
| 2010 |
Hutchinson MR, Lewis SS, Coats BD, Rezvani N, Zhang Y, Wieseler JL, Somogyi AA, Yin H, Maier SF, Rice KC, Watkins LR. Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences. Neuroscience. 167: 880-93. PMID 20178837 DOI: 10.1016/J.Neuroscience.2010.02.011 |
0.833 |
|
| 2010 |
Christianson JP, Ragole T, Amat J, Greenwood BN, Strong PV, Paul ED, Fleshner M, Watkins LR, Maier SF. 5-hydroxytryptamine 2C receptors in the basolateral amygdala are involved in the expression of anxiety after uncontrollable traumatic stress. Biological Psychiatry. 67: 339-45. PMID 19914601 DOI: 10.1016/J.Biopsych.2009.09.011 |
0.468 |
|
| 2010 |
Amat J, Aleksejev RM, Paul E, Watkins LR, Maier SF. Behavioral control over shock blocks behavioral and neurochemical effects of later social defeat. Neuroscience. 165: 1031-8. PMID 19909791 DOI: 10.1016/J.Neuroscience.2009.11.005 |
0.475 |
|
| 2010 |
Wieseler J, Ellis A, Sprunger D, Brown K, McFadden A, Mahoney J, Rezvani N, Maier SF, Watkins LR. A novel method for modeling facial allodynia associated with migraine in awake and freely moving rats. Journal of Neuroscience Methods. 185: 236-45. PMID 19837113 DOI: 10.1016/J.Jneumeth.2009.10.006 |
0.777 |
|
| 2010 |
Lewis SS, Hutchinson MR, Rezvani N, Loram LC, Zhang Y, Maier SF, Rice KC, Watkins LR. Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1beta. Neuroscience. 165: 569-83. PMID 19833175 DOI: 10.1016/J.Neuroscience.2009.10.011 |
0.843 |
|
| 2010 |
Frank MG, Barrientos RM, Hein AM, Biedenkapp JC, Watkins LR, Maier SF. IL-1RA blocks E. coli-induced suppression of Arc and long-term memory in aged F344xBN F1 rats. Brain, Behavior, and Immunity. 24: 254-62. PMID 19822205 DOI: 10.1016/j.bbi.2009.10.005 |
0.51 |
|
| 2010 |
Bland ST, Beckley JT, Young S, Tsang V, Watkins LR, Maier SF, Bilbo SD. Enduring consequences of early-life infection on glial and neural cell genesis within cognitive regions of the brain. Brain, Behavior, and Immunity. 24: 329-38. PMID 19782746 DOI: 10.1016/J.Bbi.2009.09.012 |
0.477 |
|
| 2010 |
Soderquist RG, Milligan ED, Harrison JA, Chavez RA, Johnson KW, Watkins LR, Mahoney MJ. PEGylation of interleukin-10 for the mitigation of enhanced pain states. Journal of Biomedical Materials Research. Part A. 93: 1169-79. PMID 19768789 DOI: 10.1002/Jbm.A.32611 |
0.644 |
|
| 2010 |
Bilbo SD, Wieseler JL, Barrientos RM, Tsang V, Watkins LR, Maier SF. Neonatal bacterial infection alters fever to live and simulated infections in adulthood. Psychoneuroendocrinology. 35: 369-81. PMID 19682802 DOI: 10.1016/j.psyneuen.2009.07.014 |
0.472 |
|
| 2010 |
Hutchinson MR, Zhang Y, Shridhar M, Evans JH, Buchanan MM, Zhao TX, Slivka PF, Coats BD, Rezvani N, Wieseler J, Hughes TS, Landgraf KE, Chan S, Fong S, Phipps S, ... ... Watkins LR, et al. Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain, Behavior, and Immunity. 24: 83-95. PMID 19679181 DOI: 10.1016/J.Bbi.2009.08.004 |
0.811 |
|
| 2010 |
Frank MG, Miguel ZD, Watkins LR, Maier SF. Prior exposure to glucocorticoids sensitizes the neuroinflammatory and peripheral inflammatory responses to E. coli lipopolysaccharide. Brain, Behavior, and Immunity. 24: 19-30. PMID 19647070 DOI: 10.1016/j.bbi.2009.07.008 |
0.53 |
|
| 2010 |
Ramos K, Lewis M, Crysdale N, Zhang Y, Maier S, Watkins L. Pro-inflammatory signaling in endothelial cells and oligodendrocytes: new players in chronic pain and dysregulation of opioid efficacy The Journal of Pain. 11: S26. DOI: 10.1016/j.jpain.2010.01.110 |
0.567 |
|
| 2010 |
Hutchinson M, Wu Y, Liu L, Phipps S, Rice K, Coller J, Watkins L, Somogyi A. Opioid and alcohol action: The role of brain and spinal cord innate immune signalling Brain, Behavior, and Immunity. 24: S19. DOI: 10.1016/J.Bbi.2010.07.060 |
0.767 |
|
| 2010 |
Watkins LR, Milligan ED, Maier SF. Mechanisms of Glial Activation after Nerve Injury The Senses: a Comprehensive Reference. 5: 429-433. DOI: 10.1016/B978-012370880-9.00173-0 |
0.617 |
|
| 2009 |
Loram LC, Harrison JA, Sloane EM, Hutchinson MR, Sholar P, Taylor FR, Berkelhammer D, Coats BD, Poole S, Milligan ED, Maier SF, Rieger J, Watkins LR. Enduring reversal of neuropathic pain by a single intrathecal injection of adenosine 2A receptor agonists: a novel therapy for neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14015-25. PMID 19890011 DOI: 10.1523/Jneurosci.3447-09.2009 |
0.831 |
|
| 2009 |
Hutchinson MR, Ramos KM, Loram LC, Wieseler J, Sholar PW, Kearney JJ, Lewis MT, Crysdale NY, Zhang Y, Harrison JA, Maier SF, Rice KC, Watkins LR. Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats. Neuroscience. 164: 1821-32. PMID 19788917 DOI: 10.1016/J.Neuroscience.2009.09.046 |
0.809 |
|
| 2009 |
Watkins LR, Hutchinson MR, Rice KC, Maier SF. The "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia. Trends in Pharmacological Sciences. 30: 581-91. PMID 19762094 DOI: 10.1016/J.Tips.2009.08.002 |
0.804 |
|
| 2009 |
Baratta MV, Zarza CM, Gomez DM, Campeau S, Watkins LR, Maier SF. Selective activation of dorsal raphe nucleus-projecting neurons in the ventral medial prefrontal cortex by controllable stress. The European Journal of Neuroscience. 30: 1111-6. PMID 19686468 DOI: 10.1111/J.1460-9568.2009.06867.X |
0.473 |
|
| 2009 |
Sloane E, Langer S, Jekich B, Mahoney J, Hughes T, Frank M, Seibert W, Huberty G, Coats B, Harrison J, Klinman D, Poole S, Maier S, Johnson K, Chavez R, ... Watkins LR, et al. Immunological priming potentiates non-viral anti-inflammatory gene therapy treatment of neuropathic pain. Gene Therapy. 16: 1210-22. PMID 19571887 DOI: 10.1038/Gt.2009.79 |
0.815 |
|
| 2009 |
Rodgers KM, Hutchinson MR, Northcutt A, Maier SF, Watkins LR, Barth DS. The cortical innate immune response increases local neuronal excitability leading to seizures. Brain : a Journal of Neurology. 132: 2478-86. PMID 19567702 DOI: 10.1093/Brain/Awp177 |
0.787 |
|
| 2009 |
Bartley J, Watkins LR. Comment on: excessive opioid use and the development of chronic migraine. Pain. 145: 262-3. PMID 19553017 DOI: 10.1016/j.pain.2009.06.007 |
0.326 |
|
| 2009 |
Hughes TS, Langer SJ, Virtanen SI, Chavez RA, Watkins LR, Milligan ED, Leinwand LA. Immunogenicity of intrathecal plasmid gene delivery: cytokine release and effects on transgene expression. The Journal of Gene Medicine. 11: 782-90. PMID 19533588 DOI: 10.1002/Jgm.1364 |
0.636 |
|
| 2009 |
Bland ST, Hutchinson MR, Maier SF, Watkins LR, Johnson KW. The glial activation inhibitor AV411 reduces morphine-induced nucleus accumbens dopamine release. Brain, Behavior, and Immunity. 23: 492-7. PMID 19486648 DOI: 10.1016/J.Bbi.2009.01.014 |
0.762 |
|
| 2009 |
Barrientos RM, Watkins LR, Rudy JW, Maier SF. Characterization of the sickness response in young and aging rats following E. coli infection. Brain, Behavior, and Immunity. 23: 450-4. PMID 19486645 DOI: 10.1016/j.bbi.2009.01.016 |
0.456 |
|
| 2009 |
Sloane EM, Soderquist RG, Maier SF, Mahoney MJ, Watkins LR, Milligan ED. Long-term control of neuropathic pain in a non-viral gene therapy paradigm. Gene Therapy. 16: 470-5. PMID 19262611 DOI: 10.1038/Gt.2009.21 |
0.828 |
|
| 2009 |
Slivka PF, Shridhar M, Lee GI, Sammond DW, Hutchinson MR, Martinko AJ, Buchanan MM, Sholar PW, Kearney JJ, Harrison JA, Watkins LR, Yin H. A peptide antagonist of the TLR4-MD2 interaction. Chembiochem : a European Journal of Chemical Biology. 10: 645-9. PMID 19184989 DOI: 10.1002/Cbic.200800769 |
0.785 |
|
| 2009 |
Milligan ED, Watkins LR. Pathological and protective roles of glia in chronic pain. Nature Reviews. Neuroscience. 10: 23-36. PMID 19096368 DOI: 10.1038/Nrn2533 |
0.675 |
|
| 2009 |
Christianson JP, Thompson BM, Watkins LR, Maier SF. Medial prefrontal cortical activation modulates the impact of controllable and uncontrollable stressor exposure on a social exploration test of anxiety in the rat. Stress (Amsterdam, Netherlands). 12: 445-50. PMID 19051125 DOI: 10.1080/10253890802510302 |
0.47 |
|
| 2009 |
Soderquist RG, Milligan ED, Sloane EM, Harrison JA, Douvas KK, Potter JM, Hughes TS, Chavez RA, Johnson K, Watkins LR, Mahoney MJ. PEGylation of brain-derived neurotrophic factor for preserved biological activity and enhanced spinal cord distribution. Journal of Biomedical Materials Research. Part A. 91: 719-29. PMID 19048635 DOI: 10.1002/Jbm.A.32254 |
0.78 |
|
| 2009 |
Hughes TS, Langer SJ, Johnson KW, Chavez RA, Watkins LR, Milligan ED, Leinwand LA. Intrathecal injection of naked plasmid DNA provides long-term expression of secreted proteins. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 88-94. PMID 18941439 DOI: 10.1038/Mt.2008.230 |
0.584 |
|
| 2009 |
Hutchinson MR, Lewis SS, Coats BD, Skyba DA, Crysdale NY, Berkelhammer DL, Brzeski A, Northcutt A, Vietz CM, Judd CM, Maier SF, Watkins LR, Johnson KW. Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast). Brain, Behavior, and Immunity. 23: 240-50. PMID 18938237 DOI: 10.1016/J.Bbi.2008.09.012 |
0.807 |
|
| 2009 |
Sloane E, Ledeboer A, Seibert W, Coats B, van Strien M, Maier SF, Johnson KW, Chavez R, Watkins LR, Leinwand L, Milligan ED, Van Dam AM. Anti-inflammatory cytokine gene therapy decreases sensory and motor dysfunction in experimental Multiple Sclerosis: MOG-EAE behavioral and anatomical symptom treatment with cytokine gene therapy. Brain, Behavior, and Immunity. 23: 92-100. PMID 18835435 DOI: 10.1016/J.Bbi.2008.09.004 |
0.794 |
|
| 2009 |
Barrientos RM, Frank MG, Hein AM, Higgins EA, Watkins LR, Rudy JW, Maier SF. Time course of hippocampal IL-1 beta and memory consolidation impairments in aging rats following peripheral infection. Brain, Behavior, and Immunity. 23: 46-54. PMID 18664380 DOI: 10.1016/J.Bbi.2008.07.002 |
0.477 |
|
| 2009 |
Rozeske RR, Der-Avakian A, Bland ST, Beckley JT, Watkins LR, Maier SF. The medial prefrontal cortex regulates the differential expression of morphine-conditioned place preference following a single exposure to controllable or uncontrollable stress. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 834-43. PMID 18368036 DOI: 10.1038/Npp.2008.34 |
0.501 |
|
| 2009 |
Loram L, Sholar P, Taylor F, Harrison J, Hutchinson M, Maier S, Rieger J, Watkins L, Sloane E. Adenosine 2A receptor agonist produces long-duration reversal of neuropathic pain via sustained release of spinal interleukin-10 The Journal of Pain. 10: S39. DOI: 10.1016/J.Jpain.2009.01.165 |
0.819 |
|
| 2009 |
Loram L, Sloane E, Harrison J, Sholar P, Taylor F, Hutchinson M, Maier S, Rieger J, Watkins L. 80. Long-duration reversal of neuropathic pain via sustained release of spinal interleukin-10 is mediated by adenosine 2A receptor activation Brain, Behavior, and Immunity. 23: S47. DOI: 10.1016/J.Bbi.2009.06.085 |
0.82 |
|
| 2009 |
Barrientos R, Chapman T, Ahrendsen J, Crysdale N, Frank M, Campeau S, Day H, Watkins L, Patterson S, Maier S. 9. The effects of voluntary wheel running on infection-induced memory deficits and hippocampal BDNF mRNA in aging rats Brain, Behavior, and Immunity. 23: S27. DOI: 10.1016/J.Bbi.2009.06.014 |
0.442 |
|
| 2008 |
Christianson JP, Benison AM, Jennings J, Sandsmark EK, Amat J, Kaufman RD, Baratta MV, Paul ED, Campeau S, Watkins LR, Barth DS, Maier SF. The sensory insular cortex mediates the stress-buffering effects of safety signals but not behavioral control. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13703-11. PMID 19074043 DOI: 10.1523/Jneurosci.4270-08.2008 |
0.455 |
|
| 2008 |
Hutchinson MR, Northcutt AL, Chao LW, Kearney JJ, Zhang Y, Berkelhammer DL, Loram LC, Rozeske RR, Bland ST, Maier SF, Gleeson TT, Watkins LR. Minocycline suppresses morphine-induced respiratory depression, suppresses morphine-induced reward, and enhances systemic morphine-induced analgesia. Brain, Behavior, and Immunity. 22: 1248-56. PMID 18706994 DOI: 10.1016/J.Bbi.2008.07.008 |
0.812 |
|
| 2008 |
Hutchinson MR, Zhang Y, Brown K, Coats BD, Shridhar M, Sholar PW, Patel SJ, Crysdale NY, Harrison JA, Maier SF, Rice KC, Watkins LR. Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4). The European Journal of Neuroscience. 28: 20-9. PMID 18662331 DOI: 10.1111/J.1460-9568.2008.06321.X |
0.819 |
|
| 2008 |
Hutchinson MR, Coats BD, Lewis SS, Zhang Y, Sprunger DB, Rezvani N, Baker EM, Jekich BM, Wieseler JL, Somogyi AA, Martin D, Poole S, Judd CM, Maier SF, Watkins LR. Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia. Brain, Behavior, and Immunity. 22: 1178-89. PMID 18599265 DOI: 10.1016/J.Bbi.2008.05.004 |
0.849 |
|
| 2008 |
Christianson JP, Paul ED, Irani M, Thompson BM, Kubala KH, Yirmiya R, Watkins LR, Maier SF. The role of prior stressor controllability and the dorsal raphé nucleus in sucrose preference and social exploration. Behavioural Brain Research. 193: 87-93. PMID 18554730 DOI: 10.1016/J.Bbr.2008.04.024 |
0.448 |
|
| 2008 |
Milligan ED, Sloane EM, Watkins LR. Glia in pathological pain: a role for fractalkine. Journal of Neuroimmunology. 198: 113-20. PMID 18547654 DOI: 10.1016/J.Jneuroim.2008.04.011 |
0.822 |
|
| 2008 |
Amat J, Paul E, Watkins LR, Maier SF. Activation of the ventral medial prefrontal cortex during an uncontrollable stressor reproduces both the immediate and long-term protective effects of behavioral control. Neuroscience. 154: 1178-86. PMID 18515010 DOI: 10.1016/J.Neuroscience.2008.04.005 |
0.476 |
|
| 2008 |
Baratta MV, Lucero TR, Amat J, Watkins LR, Maier SF. Role of the ventral medial prefrontal cortex in mediating behavioral control-induced reduction of later conditioned fear. Learning & Memory (Cold Spring Harbor, N.Y.). 15: 84-7. PMID 18235108 DOI: 10.1101/Lm.800308 |
0.464 |
|
| 2008 |
Bilbo SD, Yirmiya R, Amat J, Paul ED, Watkins LR, Maier SF. Bacterial infection early in life protects against stressor-induced depressive-like symptoms in adult rats. Psychoneuroendocrinology. 33: 261-9. PMID 18164556 DOI: 10.1016/J.Psyneuen.2007.11.008 |
0.472 |
|
| 2008 |
Bilbo SD, Barrientos RM, Eads AS, Northcutt A, Watkins LR, Rudy JW, Maier SF. Early-life infection leads to altered BDNF and IL-1beta mRNA expression in rat hippocampus following learning in adulthood. Brain, Behavior, and Immunity. 22: 451-5. PMID 17997277 DOI: 10.1016/J.Bbi.2007.10.003 |
0.789 |
|
| 2008 |
Spataro LE, Downs H, Wieseler J, Watkins LR, Oaklander AL, Horowitz SH. The persistent sciatic inflammatory neuropathy (sin) rat model of neuropathic pain does not involve small-fiber axon damage Journal of Neuropathic Pain and Symptom Palliation. 2: 41-47. DOI: 10.1300/J426v02n04_05 |
0.803 |
|
| 2008 |
Bilbo SD, Wieseler J, Barrientos RM, Watkins LR, Maier SF. 12. Rats infected early in life with bacteria exhibit exaggerated fever, sickness behavior, and lack of endotoxin tolerance in adulthood Brain, Behavior, and Immunity. 22: 3-4. DOI: 10.1016/j.bbi.2008.04.018 |
0.448 |
|
| 2007 |
Hein AM, Stutzman DL, Bland ST, Barrientos RM, Watkins LR, Rudy JW, Maier SF. Prostaglandins are necessary and sufficient to induce contextual fear learning impairments after interleukin-1 beta injections into the dorsal hippocampus. Neuroscience. 150: 754-63. PMID 18035502 DOI: 10.1016/J.Neuroscience.2007.10.003 |
0.468 |
|
| 2007 |
Hutchinson MR, Bland ST, Johnson KW, Rice KC, Maier SF, Watkins LR. Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward. Thescientificworldjournal. 7: 98-111. PMID 17982582 DOI: 10.1100/Tsw.2007.230 |
0.797 |
|
| 2007 |
Watkins LR, Hutchinson MR, Milligan ED, Maier SF. "Listening" and "talking" to neurons: implications of immune activation for pain control and increasing the efficacy of opioids. Brain Research Reviews. 56: 148-69. PMID 17706291 DOI: 10.1016/J.Brainresrev.2007.06.006 |
0.831 |
|
| 2007 |
Ledeboer A, Hutchinson MR, Watkins LR, Johnson KW. Ibudilast (AV-411). A new class therapeutic candidate for neuropathic pain and opioid withdrawal syndromes. Expert Opinion On Investigational Drugs. 16: 935-50. PMID 17594181 DOI: 10.1517/13543784.16.7.935 |
0.773 |
|
| 2007 |
Baratta MV, Christianson JP, Gomez DM, Zarza CM, Amat J, Masini CV, Watkins LR, Maier SF. Controllable versus uncontrollable stressors bi-directionally modulate conditioned but not innate fear. Neuroscience. 146: 1495-503. PMID 17478046 DOI: 10.1016/J.Neuroscience.2007.03.042 |
0.447 |
|
| 2007 |
Kleibeuker W, Ledeboer A, Eijkelkamp N, Watkins LR, Maier SF, Zijlstra J, Heijnen CJ, Kavelaars A. A role for G protein-coupled receptor kinase 2 in mechanical allodynia. The European Journal of Neuroscience. 25: 1696-704. PMID 17408432 DOI: 10.1111/j.1460-9568.2007.05423.x |
0.56 |
|
| 2007 |
Frank MG, Der-Avakian A, Bland ST, Watkins LR, Maier SF. Stress-induced glucocorticoids suppress the antisense molecular regulation of FGF-2 expression. Psychoneuroendocrinology. 32: 376-84. PMID 17383826 DOI: 10.1016/J.Psyneuen.2007.02.001 |
0.453 |
|
| 2007 |
Holguin A, Frank MG, Biedenkapp JC, Nelson K, Lippert D, Watkins LR, Rudy JW, Maier SF. Characterization of the temporo-spatial effects of chronic bilateral intrahippocampal cannulae on interleukin-1beta. Journal of Neuroscience Methods. 161: 265-72. PMID 17241670 DOI: 10.1016/j.jneumeth.2006.11.014 |
0.505 |
|
| 2007 |
Der-Avakian A, Rozeske RR, Bland ST, Watkins LR, Maier SF. The effects of a single session of inescapable tailshock on the subsequent locomotor response to brief footshock and cocaine administration in rats. Psychopharmacology. 191: 899-907. PMID 17211648 DOI: 10.1007/S00213-006-0677-8 |
0.459 |
|
| 2007 |
Der-Avakian A, Bland ST, Rozeske RR, Tamblyn JP, Hutchinson MR, Watkins LR, Maier SF. The effects of a single exposure to uncontrollable stress on the subsequent conditioned place preference responses to oxycodone, cocaine, and ethanol in rats. Psychopharmacology. 191: 909-17. PMID 17211647 DOI: 10.1007/S00213-006-0678-7 |
0.751 |
|
| 2007 |
Schoeniger-Skinner DK, Ledeboer A, Frank MG, Milligan ED, Poole S, Martin D, Maier SF, Watkins LR. Interleukin-6 mediates low-threshold mechanical allodynia induced by intrathecal HIV-1 envelope glycoprotein gp120. Brain, Behavior, and Immunity. 21: 660-7. PMID 17204394 DOI: 10.1016/J.Bbi.2006.10.010 |
0.714 |
|
| 2007 |
Bland ST, Tamlyn JP, Barrientos RM, Greenwood BN, Watkins LR, Campeau S, Day HE, Maier SF. Expression of fibroblast growth factor-2 and brain-derived neurotrophic factor mRNA in the medial prefrontal cortex and hippocampus after uncontrollable or controllable stress. Neuroscience. 144: 1219-28. PMID 17197100 DOI: 10.1016/J.Neuroscience.2006.11.026 |
0.459 |
|
| 2007 |
Watkins LR, Hutchinson MR, Ledeboer A, Wieseler-Frank J, Milligan ED, Maier SF. Norman Cousins Lecture. Glia as the "bad guys": implications for improving clinical pain control and the clinical utility of opioids. Brain, Behavior, and Immunity. 21: 131-46. PMID 17175134 DOI: 10.1016/J.Bbi.2006.10.011 |
0.838 |
|
| 2007 |
Ledeboer A, Jekich BM, Sloane EM, Mahoney JH, Langer SJ, Milligan ED, Martin D, Maier SF, Johnson KW, Leinwand LA, Chavez RA, Watkins LR. Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. Brain, Behavior, and Immunity. 21: 686-98. PMID 17174526 DOI: 10.1016/J.Bbi.2006.10.012 |
0.827 |
|
| 2007 |
Bilbo SD, Newsum NJ, Sprunger DB, Watkins LR, Rudy JW, Maier SF. Differential effects of neonatal handling on early life infection-induced alterations in cognition in adulthood. Brain, Behavior, and Immunity. 21: 332-42. PMID 17126527 DOI: 10.1016/j.bbi.2006.10.005 |
0.469 |
|
| 2007 |
Wieseler-Frank J, Jekich BM, Mahoney JH, Bland ST, Maier SF, Watkins LR. A novel immune-to-CNS communication pathway: cells of the meninges surrounding the spinal cord CSF space produce proinflammatory cytokines in response to an inflammatory stimulus. Brain, Behavior, and Immunity. 21: 711-8. PMID 16989980 DOI: 10.1016/J.Bbi.2006.07.004 |
0.567 |
|
| 2007 |
Frank MG, Baratta MV, Sprunger DB, Watkins LR, Maier SF. Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses. Brain, Behavior, and Immunity. 21: 47-59. PMID 16647243 DOI: 10.1016/J.Bbi.2006.03.005 |
0.536 |
|
| 2007 |
Watkins LR, Wieseler-Frank J, Hutchinson MR, Ledeboer A, Spataro L, Milligan ED, Sloane EM, Maier SF. Neuroimmune interactions and pain: The role of immune and glial cells Psychoneuroimmunology, Two-Volume Set. 1: 393-414. DOI: 10.1016/B978-012088576-3/50023-X |
0.808 |
|
| 2006 |
Watkins LR, Wieseler-Frank J, Milligan ED, Johnston I, Maier SF. Chapter 22 Contribution of glia to pain processing in health and disease. Handbook of Clinical Neurology. 81: 309-23. PMID 18808844 DOI: 10.1016/S0072-9752(06)80026-6 |
0.74 |
|
| 2006 |
Ledeboer A, Liu T, Shumilla JA, Mahoney JH, Vijay S, Gross MI, Vargas JA, Sultzbaugh L, Claypool MD, Sanftner LM, Watkins LR, Johnson KW. The glial modulatory drug AV411 attenuates mechanical allodynia in rat models of neuropathic pain. Neuron Glia Biology. 2: 279-91. PMID 18176632 DOI: 10.1017/S1740925X0700035X |
0.478 |
|
| 2006 |
Milligan ED, Soderquist RG, Malone SM, Mahoney JH, Hughes TS, Langer SJ, Sloane EM, Maier SF, Leinwand LA, Watkins LR, Mahoney MJ. Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain. Neuron Glia Biology. 2: 293-308. PMID 18079973 DOI: 10.1017/S1740925X07000488 |
0.825 |
|
| 2006 |
Maier SF, Amat J, Baratta MV, Paul E, Watkins LR. Behavioral control, the medial prefrontal cortex, and resilience. Dialogues in Clinical Neuroscience. 8: 397-406. PMID 17290798 |
0.377 |
|
| 2006 |
Amat J, Paul E, Zarza C, Watkins LR, Maier SF. Previous experience with behavioral control over stress blocks the behavioral and dorsal raphe nucleus activating effects of later uncontrollable stress: role of the ventral medial prefrontal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13264-72. PMID 17182776 DOI: 10.1523/Jneurosci.3630-06.2006 |
0.481 |
|
| 2006 |
Ledeboer A, Mahoney JH, Milligan ED, Martin D, Maier SF, Watkins LR. Spinal cord glia and interleukin-1 do not appear to mediate persistent allodynia induced by intramuscular acidic saline in rats. The Journal of Pain : Official Journal of the American Pain Society. 7: 757-67. PMID 17018336 DOI: 10.1016/J.Jpain.2006.04.001 |
0.739 |
|
| 2006 |
Milligan ED, Sloane EM, Langer SJ, Hughes TS, Jekich BM, Frank MG, Mahoney JH, Levkoff LH, Maier SF, Cruz PE, Flotte TR, Johnson KW, Mahoney MM, Chavez RA, Leinwand LA, ... Watkins LR, et al. Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain. Pain. 126: 294-308. PMID 16949747 DOI: 10.1016/J.Pain.2006.07.009 |
0.829 |
|
| 2006 |
Banks WA, Watkins LR. Mediation of chronic pain: not by neurons alone. Pain. 124: 1-2. PMID 16630695 DOI: 10.1016/j.pain.2006.03.001 |
0.377 |
|
| 2006 |
Bland ST, Schmid MJ, Greenwood BN, Watkins LR, Maier SF. Behavioral control of the stressor modulates stress-induced changes in neurogenesis and fibroblast growth factor-2. Neuroreport. 17: 593-7. PMID 16603918 DOI: 10.1097/00001756-200604240-00008 |
0.467 |
|
| 2006 |
Der-Avakian A, Bland ST, Schmid MJ, Watkins LR, Spencer RL, Maier SF. The role of glucocorticoids in the uncontrollable stress-induced potentiation of nucleus accumbens shell dopamine and conditioned place preference responses to morphine. Psychoneuroendocrinology. 31: 653-63. PMID 16584846 DOI: 10.1016/J.Psyneuen.2006.02.004 |
0.532 |
|
| 2006 |
Bilbo SD, Rudy JW, Watkins LR, Maier SF. A behavioural characterization of neonatal infection-facilitated memory impairment in adult rats. Behavioural Brain Research. 169: 39-47. PMID 16413067 DOI: 10.1016/j.bbr.2005.12.002 |
0.46 |
|
| 2006 |
Frank MG, Wieseler-Frank JL, Watkins LR, Maier SF. Rapid isolation of highly enriched and quiescent microglia from adult rat hippocampus: immunophenotypic and functional characteristics. Journal of Neuroscience Methods. 151: 121-30. PMID 16125247 DOI: 10.1016/j.jneumeth.2005.06.026 |
0.449 |
|
| 2006 |
Barrientos RM, Higgins EA, Biedenkapp JC, Sprunger DB, Wright-Hardesty KJ, Watkins LR, Rudy JW, Maier SF. Peripheral infection and aging interact to impair hippocampal memory consolidation. Neurobiology of Aging. 27: 723-32. PMID 15893410 DOI: 10.1016/j.neurobiolaging.2005.03.010 |
0.459 |
|
| 2006 |
Frank MG, Barrientos RM, Biedenkapp JC, Rudy JW, Watkins LR, Maier SF. mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging. Neurobiology of Aging. 27: 717-22. PMID 15890435 DOI: 10.1016/j.neurobiolaging.2005.03.013 |
0.462 |
|
| 2006 |
Langer SJ, Busha D, Milligan ED, Hughes TS, Wieseler-Frank J, Watkins LR, Leinwand LA. 261. In Vivo Over-Expression of Fractalkine, a Putative Neuron-to-Glia Signal, To Characterize Underlying Mechanisms of Neuropathic Pain Molecular Therapy. 13: S100. DOI: 10.1016/J.Ymthe.2006.08.288 |
0.714 |
|
| 2006 |
Hughes T, Langer S, Sloane E, Mahoney J, Jekich B, Johnson K, Chavez R, Milligan E, Watkins L, Leinwand L. 260. ITRs Necessary for IL-10 Encoding Naked Plasmid Induced Reversal of Chronic Pain State in Rat Molecular Therapy. 13: S100. DOI: 10.1016/J.Ymthe.2006.08.287 |
0.831 |
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| 2006 |
Milligan ED, Langer SJ, Hughes TS, Sloane EM, Mahoney JH, Jekich BM, Maier SF, Leinwand LA, Watkins LR. 259. Plasmid DNA Encoding the Anti-Inflammatory Cytokine Gene, Interleukin-10 (IL-10) for Chronic Pain Control: Taking Advantage of Nuclear Scaffold/Matrix Attachment Regions Molecular Therapy. 13: S99. DOI: 10.1016/J.Ymthe.2006.08.286 |
0.82 |
|
| 2006 |
Bilbo SD, Newsum NJ, Mahoney JH, Sprunger DP, Watkins LR, Rudy JW, Maier SF. Maternal care modulation of neonatal infection-facilitated cognitive impairment in adulthood Frontiers in Neuroendocrinology. 27: 107. DOI: 10.1016/j.yfrne.2006.03.265 |
0.404 |
|
| 2006 |
Ledeboer A, Mahoney J, Maier S, Watkins L, Johnson K. (330/619) The Journal of Pain. 7: S7. DOI: 10.1016/j.jpain.2006.01.433 |
0.455 |
|
| 2006 |
Milligan E, Mahoney M, Soderquist R, Sloane E, Coats B, Mahoney J, Langer S, Leinwand L, Maier S, Chavez R, Watkins L. (624) The Journal of Pain. 7: S14. DOI: 10.1016/J.Jpain.2006.01.026 |
0.777 |
|
| 2006 |
Busha D, Milligan E, Murphy C, Mahoney J, Coats B, Langer S, Leinwand L, Chavez R, Maier S, Watkins L. (623) The Journal of Pain. 7: S13. DOI: 10.1016/J.Jpain.2006.01.025 |
0.656 |
|
| 2006 |
Ledeboer A, Jekich BM, Sloane EM, Langer SJ, Milligan ED, Mahoney JH, Maier SF, Leinwand LA, Chavez RA, Watkins LR, Johnson KW. Novel approaches to control paclitaxel-induced neuropathic pain: Efficacy of interleukin-10 gene therapy and the blood–brain barrier permeable glial modulator, AV411 Brain, Behavior, and Immunity. 20: 43. DOI: 10.1016/J.Bbi.2006.04.082 |
0.808 |
|
| 2005 |
Milligan E, Zapata V, Schoeniger D, Chacur M, Green P, Poole S, Martin D, Maier SF, Watkins LR. An initial investigation of spinal mechanisms underlying pain enhancement induced by fractalkine, a neuronally released chemokine. The European Journal of Neuroscience. 22: 2775-82. PMID 16324111 DOI: 10.1111/J.1460-9568.2005.04470.X |
0.758 |
|
| 2005 |
Ledeboer A, Gamanos M, Lai W, Martin D, Maier SF, Watkins LR, Quan N. Involvement of spinal cord nuclear factor kappaB activation in rat models of proinflammatory cytokine-mediated pain facilitation. The European Journal of Neuroscience. 22: 1977-86. PMID 16262636 DOI: 10.1111/j.1460-9568.2005.04379.x |
0.568 |
|
| 2005 |
Watkins LR, Hutchinson MR, Johnston IN, Maier SF. Glia: novel counter-regulators of opioid analgesia. Trends in Neurosciences. 28: 661-9. PMID 16246435 DOI: 10.1016/j.tins.2005.10.001 |
0.804 |
|
| 2005 |
Wieseler-Frank J, Maier SF, Watkins LR. Central proinflammatory cytokines and pain enhancement. Neuro-Signals. 14: 166-74. PMID 16215299 DOI: 10.1159/000087655 |
0.608 |
|
| 2005 |
Bilbo SD, Biedenkapp JC, Der-Avakian A, Watkins LR, Rudy JW, Maier SF. Neonatal infection-induced memory impairment after lipopolysaccharide in adulthood is prevented via caspase-1 inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8000-9. PMID 16135757 DOI: 10.1523/Jneurosci.1748-05.2005 |
0.506 |
|
| 2005 |
Bland ST, Schmid MJ, Der-Avakian A, Watkins LR, Spencer RL, Maier SF. Expression of c-fos and BDNF mRNA in subregions of the prefrontal cortex of male and female rats after acute uncontrollable stress. Brain Research. 1051: 90-9. PMID 15993862 DOI: 10.1016/J.Brainres.2005.05.065 |
0.442 |
|
| 2005 |
Takase LF, Nogueira MI, Bland ST, Baratta M, Watkins LR, Maier SF, Fornal CA, Jacobs BL. Effect of number of tailshocks on learned helplessness and activation of serotonergic and noradrenergic neurons in the rat. Behavioural Brain Research. 162: 299-306. PMID 15913803 DOI: 10.1016/J.Bbr.2005.04.008 |
0.461 |
|
| 2005 |
Maier SF, Watkins LR. Stressor controllability and learned helplessness: the roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor. Neuroscience and Biobehavioral Reviews. 29: 829-41. PMID 15893820 DOI: 10.1016/j.neubiorev.2005.03.021 |
0.469 |
|
| 2005 |
Milligan ED, Langer SJ, Sloane EM, He L, Wieseler-Frank J, O'Connor K, Martin D, Forsayeth JR, Maier SF, Johnson K, Chavez RA, Leinwand LA, Watkins LR. Controlling pathological pain by adenovirally driven spinal production of the anti-inflammatory cytokine, interleukin-10. The European Journal of Neuroscience. 21: 2136-48. PMID 15869510 DOI: 10.1111/J.1460-9568.2005.04057.X |
0.82 |
|
| 2005 |
Ledeboer A, Sloane EM, Milligan ED, Frank MG, Mahony JH, Maier SF, Watkins LR. Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation. Pain. 115: 71-83. PMID 15836971 DOI: 10.1016/J.Pain.2005.02.009 |
0.838 |
|
| 2005 |
Der-Avakian A, Will MJ, Bland ST, Deak T, Nguyen KT, Schmid MJ, Spencer RL, Watkins LR, Maier SF. Surgical and pharmacological suppression of glucocorticoids prevents the enhancement of morphine conditioned place preference by uncontrollable stress in rats. Psychopharmacology. 179: 409-17. PMID 15821955 DOI: 10.1007/S00213-004-2041-1 |
0.808 |
|
| 2005 |
Milligan ED, Sloane EM, Langer SJ, Cruz PE, Chacur M, Spataro L, Wieseler-Frank J, Hammack SE, Maier SF, Flotte TR, Forsayeth JR, Leinwand LA, Chavez R, Watkins LR. Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10. Molecular Pain. 1: 9. PMID 15813997 DOI: 10.1186/1744-8069-1-9 |
0.827 |
|
| 2005 |
Twining CM, Sloane EM, Schoeniger DK, Milligan ED, Martin D, Marsh H, Maier SF, Watkins LR. Activation of the spinal cord complement cascade might contribute to mechanical allodynia induced by three animal models of spinal sensitization. The Journal of Pain : Official Journal of the American Pain Society. 6: 174-83. PMID 15772911 DOI: 10.1016/J.Jpain.2004.11.011 |
0.83 |
|
| 2005 |
Bilbo SD, Levkoff LH, Mahoney JH, Watkins LR, Rudy JW, Maier SF. Neonatal infection induces memory impairments following an immune challenge in adulthood. Behavioral Neuroscience. 119: 293-301. PMID 15727533 DOI: 10.1037/0735-7044.119.1.293 |
0.485 |
|
| 2005 |
Amat J, Baratta MV, Paul E, Bland ST, Watkins LR, Maier SF. Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus. Nature Neuroscience. 8: 365-71. PMID 15696163 DOI: 10.1038/Nn1399 |
0.462 |
|
| 2005 |
Wieseler-Frank J, Maier SF, Watkins LR. Immune-to-brain communication dynamically modulates pain: physiological and pathological consequences. Brain, Behavior, and Immunity. 19: 104-11. PMID 15664782 DOI: 10.1016/j.bbi.2004.08.004 |
0.613 |
|
| 2005 |
Watkins LR, Maier SF. Immune regulation of central nervous system functions: from sickness responses to pathological pain. Journal of Internal Medicine. 257: 139-55. PMID 15656873 DOI: 10.1111/j.1365-2796.2004.01443.x |
0.584 |
|
| 2005 |
Milligan ED, Mahoney MJ, Langer SJ, Hughes T, Sloane EM, Mahoney J, Jekich B, Cruz PE, Flotte TR, Maier SF, Johnson KW, Leinwand LA, Chavez RA, Watkins LR. 644. Gene Delivery for Chronic Pain Control: Micrcroencapsulated Plasmid DNA Encoding the Anti-Inflammatory Cytokine Gene, Interleukin-10 (IL-10) Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.184 |
0.816 |
|
| 2005 |
Spataro L, Wieseler-Frank J, Bloss E, Maier S, Watkins L. Peripheral inflammation sensitizes dorsal spinal cord glia: Enhanced glial responsiveness & pain facilitation The Journal of Pain. 6: S19. DOI: 10.1016/J.Jpain.2005.01.072 |
0.819 |
|
| 2005 |
Spataro LE, Wieseler-Frank J, Milligan ED, Jekich BM, Sprunger DB, Maier SF, Fleshner M, Johnson JD, Watkins LR. #130 Prior peripheral challenge may exacerbate later immune responses Brain, Behavior, and Immunity. 19: e67. DOI: 10.1016/J.Bbi.2005.10.137 |
0.786 |
|
| 2005 |
Kleibeuker W, Ledeboer A, Zijlstra J, Maier SF, Watkins LR, Heijnen CJ, Kavelaars A. #75 IL-1β-induced reduction in spinal cord GRK2 as an underlying mechanism for chronic, inflammatory hyperalgesia Brain, Behavior, and Immunity. 19: e39. DOI: 10.1016/j.bbi.2005.10.081 |
0.529 |
|
| 2005 |
Frank MG, Baratta MV, Watkins LR, Maier SF. #42 Uncontrollable stress potentiates hippocampal microglia responses to lipopolysaccharide ex vivo Brain, Behavior, and Immunity. 19: e22. DOI: 10.1016/J.Bbi.2005.10.048 |
0.452 |
|
| 2005 |
Barrientos RM, Higgins EA, Biedenkapp JC, Frank MG, Watkins LR, Rudy JW, Maier SF. #5 Differences in IL1β expression in brain and periphery between young and aging rats 2h to 2 week following an ip E. coli injection Brain, Behavior, and Immunity. 19: e3. DOI: 10.1016/j.bbi.2005.10.011 |
0.445 |
|
| 2004 |
O'Connor KA, Ginsberg AB, Maksimova E, Wieseler Frank JL, Johnson JD, Spencer RL, Campeau S, Watkins LR, Maier SF. Stress-induced sensitization of the hypothalamic-pituitary adrenal axis is associated with alterations of hypothalamic and pituitary gene expression. Neuroendocrinology. 80: 252-63. PMID 15627803 DOI: 10.1159/000082876 |
0.47 |
|
| 2004 |
Bland ST, Schmid MJ, Watkins LR, Maier SF. Prefrontal cortex serotonin, stress, and morphine-induced nucleus accumbens dopamine. Neuroreport. 15: 2637-41. PMID 15570168 DOI: 10.1097/00001756-200412030-00016 |
0.469 |
|
| 2004 |
Amat J, Tamblyn JP, Paul ED, Bland ST, Amat P, Foster AC, Watkins LR, Maier SF. Microinjection of urocortin 2 into the dorsal raphe nucleus activates serotonergic neurons and increases extracellular serotonin in the basolateral amygdala. Neuroscience. 129: 509-19. PMID 15541873 DOI: 10.1016/J.Neuroscience.2004.07.052 |
0.465 |
|
| 2004 |
Milligan ED, Zapata V, Chacur M, Schoeniger D, Biedenkapp J, O'Connor KA, Verge GM, Chapman G, Green P, Foster AC, Naeve GS, Maier SF, Watkins LR. Evidence that exogenous and endogenous fractalkine can induce spinal nociceptive facilitation in rats. The European Journal of Neuroscience. 20: 2294-302. PMID 15525271 DOI: 10.1111/J.1460-9568.2004.03709.X |
0.743 |
|
| 2004 |
Spataro LE, Sloane EM, Milligan ED, Wieseler-Frank J, Schoeniger D, Jekich BM, Barrientos RM, Maier SF, Watkins LR. Spinal gap junctions: potential involvement in pain facilitation. The Journal of Pain : Official Journal of the American Pain Society. 5: 392-405. PMID 15501197 DOI: 10.1016/J.Jpain.2004.06.006 |
0.83 |
|
| 2004 |
Barrientos RM, Sprunger DB, Campeau S, Watkins LR, Rudy JW, Maier SF. BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1beta administration. Journal of Neuroimmunology. 155: 119-26. PMID 15342202 DOI: 10.1016/J.Jneuroim.2004.06.009 |
0.472 |
|
| 2004 |
Verge GM, Milligan ED, Maier SF, Watkins LR, Naeve GS, Foster AC. Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions. The European Journal of Neuroscience. 20: 1150-60. PMID 15341587 DOI: 10.1111/J.1460-9568.2004.03593.X |
0.739 |
|
| 2004 |
Chacur M, Gutiérrez JM, Milligan ED, Wieseler-Frank J, Britto LR, Maier SF, Watkins LR, Cury Y. Snake venom components enhance pain upon subcutaneous injection: an initial examination of spinal cord mediators. Pain. 111: 65-76. PMID 15327810 DOI: 10.1016/J.Pain.2004.06.001 |
0.748 |
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| 2004 |
Johnston IN, Milligan ED, Wieseler-Frank J, Frank MG, Zapata V, Campisi J, Langer S, Martin D, Green P, Fleshner M, Leinwand L, Maier SF, Watkins LR. A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7353-65. PMID 15317861 DOI: 10.1523/Jneurosci.1850-04.2004 |
0.74 |
|
| 2004 |
Holguin A, O'Connor KA, Biedenkapp J, Campisi J, Wieseler-Frank J, Milligan ED, Hansen MK, Spataro L, Maksimova E, Bravmann C, Martin D, Fleshner M, Maier SF, Watkins LR. HIV-1 gp120 stimulates proinflammatory cytokine-mediated pain facilitation via activation of nitric oxide synthase-I (nNOS). Pain. 110: 517-30. PMID 15288392 DOI: 10.1016/J.Pain.2004.02.018 |
0.815 |
|
| 2004 |
Johnson JD, O'Connor KA, Watkins LR, Maier SF. The role of IL-1beta in stress-induced sensitization of proinflammatory cytokine and corticosterone responses. Neuroscience. 127: 569-77. PMID 15283957 DOI: 10.1016/j.neuroscience.2004.05.046 |
0.522 |
|
| 2004 |
Twining CM, Sloane EM, Milligan ED, Chacur M, Martin D, Poole S, Marsh H, Maier SF, Watkins LR. Peri-sciatic proinflammatory cytokines, reactive oxygen species, and complement induce mirror-image neuropathic pain in rats. Pain. 110: 299-309. PMID 15275780 DOI: 10.1016/J.Pain.2004.04.008 |
0.822 |
|
| 2004 |
Takase LF, Nogueira MI, Baratta M, Bland ST, Watkins LR, Maier SF, Fornal CA, Jacobs BL. Inescapable shock activates serotonergic neurons in all raphe nuclei of rat. Behavioural Brain Research. 153: 233-9. PMID 15219724 DOI: 10.1016/J.Bbr.2003.12.020 |
0.48 |
|
| 2004 |
Bland ST, Twining C, Schmid MJ, Der-Avakian A, Watkins LR, Maier SF. Stress potentiation of morphine-induced dopamine efflux in the nucleus accumbens shell is dependent upon stressor uncontrollability and is mediated by the dorsal raphe nucleus. Neuroscience. 126: 705-15. PMID 15183519 DOI: 10.1016/J.Neuroscience.2004.04.025 |
0.51 |
|
| 2004 |
Day HE, Greenwood BN, Hammack SE, Watkins LR, Fleshner M, Maier SF, Campeau S. Differential expression of 5HT-1A, alpha 1b adrenergic, CRF-R1, and CRF-R2 receptor mRNA in serotonergic, gamma-aminobutyric acidergic, and catecholaminergic cells of the rat dorsal raphe nucleus. The Journal of Comparative Neurology. 474: 364-78. PMID 15174080 DOI: 10.1002/Cne.20138 |
0.67 |
|
| 2004 |
Wieseler-Frank J, Maier SF, Watkins LR. Glial activation and pathological pain. Neurochemistry International. 45: 389-95. PMID 15145553 DOI: 10.1016/j.neuint.2003.09.009 |
0.569 |
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| 2004 |
Milligan ED, Maier SF, Watkins LR. Sciatic inflammatory neuropathy in the rat: surgical procedures, induction of inflammation, and behavioral testing. Methods in Molecular Medicine. 99: 67-89. PMID 15131330 DOI: 10.1385/1-59259-770-X:067 |
0.714 |
|
| 2004 |
Hammack SE, Richey KJ, Watkins LR, Maier SF. Chemical lesion of the bed nucleus of the stria terminalis blocks the behavioral consequences of uncontrollable stress. Behavioral Neuroscience. 118: 443-8. PMID 15113272 DOI: 10.1037/0735-7044.118.2.443 |
0.686 |
|
| 2004 |
Chacur M, Milligan ED, Sloan EM, Wieseler-Frank J, Barrientos RM, Martin D, Poole S, Lomonte B, Gutiérrez JM, Maier SF, Cury Y, Watkins LR. Snake venom phospholipase A2s (Asp49 and Lys49) induce mechanical allodynia upon peri-sciatic administration: involvement of spinal cord glia, proinflammatory cytokines and nitric oxide. Pain. 108: 180-91. PMID 15109522 DOI: 10.1016/J.Pain.2003.12.023 |
0.753 |
|
| 2004 |
O'Connor KA, Holguin A, Hansen MK, Maier SF, Watkins LR. A method for measuring multiple cytokines from small samples. Brain, Behavior, and Immunity. 18: 274-80. PMID 15050654 DOI: 10.1016/j.bbi.2003.09.009 |
0.441 |
|
| 2004 |
Will MJ, Der-Avakian A, Bland ST, Grahn RE, Hammack SE, Sparks PD, Pepin JL, Watkins LR, Maier SF. Electrolytic lesions and pharmacological inhibition of the dorsal raphe nucleus prevent stressor potentiation of morphine conditioned place preference in rats. Psychopharmacology. 171: 191-8. PMID 13680080 DOI: 10.1007/S00213-003-1572-1 |
0.799 |
|
| 2004 |
Milligan ED, Chavez RA, Langer SJ, Sloane EM, Chacur M, Wieseler-Frank JL, Frank MG, Flotte TR, Cruz P, Leinwand L, Shumilla JA, Forsayeth JR, Maier SF, Watkins LR. 530. Spinal interleukin-10 (IL-10) gene therapy using viral and non-viral vectors controls inflammatory- and chronic constriction injury-induced pain states in rats Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.477 |
0.828 |
|
| 2004 |
Milligan E, Langer S, Sloane E, Wieseler-Frank J, Frank M, Levkoff L, Mahoney J, Chavez R, Forsayeth J, Cruz P, Flotte T, Leinwand L, Maier S, Watkins L. Animal Models of Chronic Pain The Journal of Pain. 5: S16. DOI: 10.1016/J.Jpain.2004.02.029 |
0.809 |
|
| 2004 |
Sloane E, Langer S, Milligan E, Wieseler-Frank J, Mahoney J, Levkoff L, Cruz P, Flotte T, Leinwand L, Maier S, Watkins L. Animal Models of Chronic Pain The Journal of Pain. 5: S15. DOI: 10.1016/J.Jpain.2004.02.027 |
0.809 |
|
| 2004 |
Watkins LR, Maier SF. Targeting glia to control clinical pain: An idea whose time has come Drug Discovery Today: Therapeutic Strategies. 1: 83-88. DOI: 10.1016/j.ddstr.2004.08.010 |
0.55 |
|
| 2003 |
Gazda LS, Smith T, Watkins LR, Maier SF, Fleshner M. Stressor exposure produces long-term reductions in antigen-specific T and B cell responses. Stress (Amsterdam, Netherlands). 6: 259-67. PMID 14660058 DOI: 10.1080/10253890310001594441 |
0.474 |
|
| 2003 |
Hammack SE, Pepin JL, DesMarteau JS, Watkins LR, Maier SF. Low doses of corticotropin-releasing hormone injected into the dorsal raphe nucleus block the behavioral consequences of uncontrollable stress. Behavioural Brain Research. 147: 55-64. PMID 14659570 DOI: 10.1016/S0166-4328(03)00133-5 |
0.677 |
|
| 2003 |
Watkins LR, Maier SF. Glia: a novel drug discovery target for clinical pain. Nature Reviews. Drug Discovery. 2: 973-85. PMID 14654796 DOI: 10.1038/nrd1251 |
0.552 |
|
| 2003 |
Dworkin RH, Backonja M, Rowbotham MC, Allen RR, Argoff CR, Bennett GJ, Bushnell MC, Farrar JT, Galer BS, Haythornthwaite JA, Hewitt DJ, Loeser JD, Max MB, Saltarelli M, Schmader KE, ... ... Watkins LR, et al. Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations. Archives of Neurology. 60: 1524-34. PMID 14623723 DOI: 10.1001/Archneur.60.11.1524 |
0.411 |
|
| 2003 |
O'Connor KA, Hansen MK, Rachal Pugh C, Deak MM, Biedenkapp JC, Milligan ED, Johnson JD, Wang H, Maier SF, Tracey KJ, Watkins LR. Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects. Cytokine. 24: 254-65. PMID 14609567 DOI: 10.1016/J.Cyto.2003.08.001 |
0.709 |
|
| 2003 |
Barrientos RM, Sprunger DB, Campeau S, Higgins EA, Watkins LR, Rudy JW, Maier SF. Brain-derived neurotrophic factor mRNA downregulation produced by social isolation is blocked by intrahippocampal interleukin-1 receptor antagonist. Neuroscience. 121: 847-53. PMID 14580934 DOI: 10.1016/S0306-4522(03)00564-5 |
0.478 |
|
| 2003 |
O'Connor KA, Johnson JD, Hansen MK, Wieseler Frank JL, Maksimova E, Watkins LR, Maier SF. Peripheral and central proinflammatory cytokine response to a severe acute stressor. Brain Research. 991: 123-32. PMID 14575884 DOI: 10.1016/j.brainres.2003.08.006 |
0.49 |
|
| 2003 |
Brennan FX, Grahn RE, Watkins LR, Maier SF. Serum cholesterol levels and stressor controllability in rats. Physiology & Behavior. 79: 757-60. PMID 12954419 DOI: 10.1016/S0031-9384(03)00210-5 |
0.429 |
|
| 2003 |
Campisi J, Hansen MK, O'Connor KA, Biedenkapp JC, Watkins LR, Maier SF, Fleshner M. Circulating cytokines and endotoxin are not necessary for the activation of the sickness or corticosterone response produced by peripheral E. coli challenge. Journal of Applied Physiology (Bethesda, Md. : 1985). 95: 1873-82. PMID 12871965 DOI: 10.1152/Japplphysiol.00371.2003 |
0.518 |
|
| 2003 |
Bland ST, Hargrave D, Pepin JL, Amat J, Watkins LR, Maier SF. Stressor controllability modulates stress-induced dopamine and serotonin efflux and morphine-induced serotonin efflux in the medial prefrontal cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1589-96. PMID 12784102 DOI: 10.1038/Sj.Npp.1300206 |
0.487 |
|
| 2003 |
Bland ST, Twining C, Watkins LR, Maier SF. Stressor controllability modulates stress-induced serotonin but not dopamine efflux in the nucleus accumbens shell. Synapse (New York, N.Y.). 49: 206-8. PMID 12774305 DOI: 10.1002/Syn.10229 |
0.458 |
|
| 2003 |
O'Connor KA, Johnson JD, Hammack SE, Brooks LM, Spencer RL, Watkins LR, Maier SF. Inescapable shock induces resistance to the effects of dexamethasone. Psychoneuroendocrinology. 28: 481-500. PMID 12689607 DOI: 10.1016/S0306-4530(02)00035-5 |
0.712 |
|
| 2003 |
Watkins LR, Milligan ED, Maier SF. Glial proinflammatory cytokines mediate exaggerated pain states: implications for clinical pain. Advances in Experimental Medicine and Biology. 521: 1-21. PMID 12617561 |
0.713 |
|
| 2003 |
Maier SF, Watkins LR. Immune-to-central nervous system communication and its role in modulating pain and cognition: Implications for cancer and cancer treatment. Brain, Behavior, and Immunity. 17: S125-31. PMID 12615198 DOI: 10.1016/S0889-1591(02)00079-X |
0.556 |
|
| 2003 |
Milligan ED, Twining C, Chacur M, Biedenkapp J, O'Connor K, Poole S, Tracey K, Martin D, Maier SF, Watkins LR. Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1026-40. PMID 12574433 DOI: 10.1523/Jneurosci.23-03-01026.2003 |
0.746 |
|
| 2003 |
Hammack SE, Schmid MJ, LoPresti ML, Der-Avakian A, Pellymounter MA, Foster AC, Watkins LR, Maier SF. Corticotropin releasing hormone type 2 receptors in the dorsal raphe nucleus mediate the behavioral consequences of uncontrollable stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1019-25. PMID 12574432 DOI: 10.1523/Jneurosci.23-03-01019.2003 |
0.698 |
|
| 2003 |
Johnson JD, O'Connor KA, Hansen MK, Watkins LR, Maier SF. Effects of prior stress on LPS-induced cytokine and sickness responses. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 284: R422-32. PMID 12399247 DOI: 10.1152/ajpregu.00230.2002 |
0.475 |
|
| 2003 |
Watkins LR, Maier SF. When Good Pain Turns Bad Current Directions in Psychological Science. 12: 232-236. DOI: 10.1046/j.0963-7214.2003.01268.x |
0.584 |
|
| 2003 |
Milligan ED, Maier SF, Watkins LR. Review: Neuronal-glial interactions in central sensitization Seminars in Pain Medicine. 1: 171-183. DOI: 10.1016/S1537-5897(03)00044-2 |
0.73 |
|
| 2002 |
Watkins LR, Maier SF. Beyond neurons: evidence that immune and glial cells contribute to pathological pain states. Physiological Reviews. 82: 981-1011. PMID 12270950 DOI: 10.1152/physrev.00011.2002 |
0.587 |
|
| 2002 |
Grahn RE, Hammack SE, Will MJ, O'Connor KA, Deak T, Sparks PD, Watkins LR, Maier SF. Blockade of alpha1 adrenoreceptors in the dorsal raphe nucleus prevents enhanced conditioned fear and impaired escape performance following uncontrollable stressor exposure in rats. Behavioural Brain Research. 134: 387-92. PMID 12191825 DOI: 10.1016/S0166-4328(02)00061-X |
0.791 |
|
| 2002 |
Barrientos RM, Higgins EA, Sprunger DB, Watkins LR, Rudy JW, Maier SF. Memory for context is impaired by a post context exposure injection of interleukin-1 beta into dorsal hippocampus. Behavioural Brain Research. 134: 291-8. PMID 12191816 DOI: 10.1016/S0166-4328(02)00043-8 |
0.481 |
|
| 2002 |
Johnson JD, O'Connor KA, Deak T, Stark M, Watkins LR, Maier SF. Prior stressor exposure sensitizes LPS-induced cytokine production. Brain, Behavior, and Immunity. 16: 461-76. PMID 12096891 DOI: 10.1006/Brbi.2001.0638 |
0.661 |
|
| 2002 |
Moraska A, Campisi J, Nguyen KT, Maier SF, Watkins LR, Fleshner M. Elevated IL-1beta contributes to antibody suppression produced by stress. Journal of Applied Physiology (Bethesda, Md. : 1985). 93: 207-15. PMID 12070207 DOI: 10.1152/Japplphysiol.01151.2001 |
0.618 |
|
| 2002 |
Hammack SE, Richey KJ, Schmid MJ, LoPresti ML, Watkins LR, Maier SF. The role of corticotropin-releasing hormone in the dorsal raphe nucleus in mediating the behavioral consequences of uncontrollable stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1020-6. PMID 11826130 DOI: 10.1523/Jneurosci.22-03-01020.2002 |
0.696 |
|
| 2002 |
Johnson JD, O'Connor KA, Deak T, Spencer RL, Watkins LR, Maier SF. Prior stressor exposure primes the HPA axis. Psychoneuroendocrinology. 27: 353-65. PMID 11818171 DOI: 10.1016/S0306-4530(01)00057-9 |
0.634 |
|
| 2002 |
Will MJ, Der-Avakian A, Pepin JL, Durkan BT, Watkins LR, Maier SF. Modulation of the locomotor properties of morphine and amphetamine by uncontrollable stress. Pharmacology, Biochemistry, and Behavior. 71: 345-51. PMID 11812543 DOI: 10.1016/S0091-3057(01)00719-5 |
0.715 |
|
| 2001 |
Milligan ED, O'Connor KA, Armstrong CB, Hansen MK, Martin D, Tracey KJ, Maier SF, Watkins LR. Systemic administration of CNI-1493, a p38 mitogen-activated protein kinase inhibitor, blocks intrathecal human immunodeficiency virus-1 gp120-induced enhanced pain states in rats. The Journal of Pain : Official Journal of the American Pain Society. 2: 326-33. PMID 14622812 DOI: 10.1054/Jpai.2001.26174 |
0.72 |
|
| 2001 |
Gazda LS, Milligan ED, Hansen MK, Twining CM, Poulos NM, Chacur M, O'Connor KA, Armstrong C, Maier SF, Watkins LR, Myers RR. Sciatic inflammatory neuritis (SIN): behavioral allodynia is paralleled by peri-sciatic proinflammatory cytokine and superoxide production. Journal of the Peripheral Nervous System : Jpns. 6: 111-29. PMID 11817330 DOI: 10.1046/J.1529-8027.2001.006001111.X |
0.69 |
|
| 2001 |
Chacur M, Milligan ED, Gazda LS, Armstrong C, Wang H, Tracey KJ, Maier SF, Watkins LR. A new model of sciatic inflammatory neuritis (SIN): induction of unilateral and bilateral mechanical allodynia following acute unilateral peri-sciatic immune activation in rats. Pain. 94: 231-44. PMID 11731060 DOI: 10.1016/S0304-3959(01)00354-2 |
0.728 |
|
| 2001 |
Amat J, Sparks PD, Matus-Amat P, Griggs J, Watkins LR, Maier SF. The role of the habenular complex in the elevation of dorsal raphe nucleus serotonin and the changes in the behavioral responses produced by uncontrollable stress. Brain Research. 917: 118-26. PMID 11602236 DOI: 10.1016/S0006-8993(01)02934-1 |
0.475 |
|
| 2001 |
Watkins LR, Milligan ED, Maier SF. Spinal cord glia: new players in pain. Pain. 93: 201-5. PMID 11514078 DOI: 10.1016/S0304-3959(01)00359-1 |
0.712 |
|
| 2001 |
Watkins LR, Milligan ED, Maier SF. Glial activation: a driving force for pathological pain. Trends in Neurosciences. 24: 450-5. PMID 11476884 DOI: 10.1016/S0166-2236(00)01854-3 |
0.745 |
|
| 2001 |
Milligan ED, O'Connor KA, Nguyen KT, Armstrong CB, Twining C, Gaykema RP, Holguin A, Martin D, Maier SF, Watkins LR. Intrathecal HIV-1 envelope glycoprotein gp120 induces enhanced pain states mediated by spinal cord proinflammatory cytokines. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 2808-19. PMID 11306633 DOI: 10.1523/Jneurosci.21-08-02808.2001 |
0.775 |
|
| 2001 |
Goehler LE, Gaykema RP, Hansen MK, Kleiner JL, Maier SF, Watkins LR. Staphylococcal enterotoxin B induces fever, brain c-Fos expression, and serum corticosterone in rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 280: R1434-9. PMID 11294765 DOI: 10.1152/Ajpregu.2001.280.5.R1434 |
0.509 |
|
| 2001 |
Hansen MK, O'Connor KA, Goehler LE, Watkins LR, Maier SF. The contribution of the vagus nerve in interleukin-1beta-induced fever is dependent on dose. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 280: R929-34. PMID 11247812 DOI: 10.1152/Ajpregu.2001.280.4.R929 |
0.482 |
|
| 2001 |
Fleshner M, Deak T, Nguyen KT, Watkins LR, Maier SF. Endogenous glucocorticoids play a positive regulatory role in the anti-keyhole limpet hemocyanin in vivo antibody response. Journal of Immunology (Baltimore, Md. : 1950). 166: 3813-9. PMID 11238624 DOI: 10.4049/Jimmunol.166.6.3813 |
0.709 |
|
| 2001 |
Rachal Pugh C, Fleshner M, Watkins LR, Maier SF, Rudy JW. The immune system and memory consolidation: a role for the cytokine IL-1beta. Neuroscience and Biobehavioral Reviews. 25: 29-41. PMID 11166076 DOI: 10.1016/S0149-7634(00)00048-8 |
0.466 |
|
| 2001 |
Milligan ED, O'Connor KA, Nguyen KT, Armstrong CB, Twining C, Gaykema RPA, Holguin A, Martin D, Maier SF, Watkins LR. Intrathecal HIV-1 Envelope Glycoprotein gp120 Induces Enhanced Pain States Mediated by Spinal Cord Proinflammatory Cytokines The Journal of Neuroscience. 21: 2808-2819. DOI: 10.1523/JNEUROSCI.21-08-02808.2001 |
0.737 |
|
| 2000 |
Hansen MK, Daniels S, Goehler LE, Gaykema RP, Maier SF, Watkins LR. Subdiaphragmatic vagotomy does not block intraperitoneal lipopolysaccharide-induced fever. Autonomic Neuroscience : Basic & Clinical. 85: 83-7. PMID 11189031 DOI: 10.1016/S1566-0702(00)00224-1 |
0.504 |
|
| 2000 |
Gaykema RP, Goehler LE, Hansen MK, Maier SF, Watkins LR. Subdiaphragmatic vagotomy blocks interleukin-1beta-induced fever but does not reduce IL-1beta levels in the circulation. Autonomic Neuroscience : Basic & Clinical. 85: 72-7. PMID 11189029 DOI: 10.1016/S1566-0702(00)00222-8 |
0.467 |
|
| 2000 |
Goehler LE, Gaykema RP, Hansen MK, Anderson K, Maier SF, Watkins LR. Vagal immune-to-brain communication: a visceral chemosensory pathway. Autonomic Neuroscience : Basic & Clinical. 85: 49-59. PMID 11189026 DOI: 10.1016/S1566-0702(00)00219-8 |
0.496 |
|
| 2000 |
Hansen MK, Nguyen KT, Goehler LE, Gaykema RP, Fleshner M, Maier SF, Watkins LR. Effects of vagotomy on lipopolysaccharide-induced brain interleukin-1beta protein in rats. Autonomic Neuroscience : Basic & Clinical. 85: 119-26. PMID 11189018 DOI: 10.1016/S1566-0702(00)00230-7 |
0.609 |
|
| 2000 |
Grahn RE, Watkins LR, Maier SF. Impaired escape performance and enhanced conditioned fear in rats following exposure to an uncontrollable stressor are mediated by glutamate and nitric oxide in the dorsal raphe nucleus. Behavioural Brain Research. 112: 33-41. PMID 10862933 DOI: 10.1016/S0166-4328(00)00161-3 |
0.487 |
|
| 2000 |
Borovikova LV, Ivanova S, Zhang M, Yang H, Botchkina GI, Watkins LR, Wang H, Abumrad N, Eaton JW, Tracey KJ. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature. 405: 458-62. PMID 10839541 DOI: 10.1038/35013070 |
0.358 |
|
| 2000 |
Van Dam AM, Bol JG, Gaykema RP, Goehler LE, Maier SF, Watkins LR, Tilders FJ. Vagotomy does not inhibit high dose lipopolysaccharide-induced interleukin-1beta immunoreactivity in rat brain and pituitary gland. Neuroscience Letters. 285: 169-72. PMID 10806313 DOI: 10.1016/S0304-3940(00)01031-4 |
0.506 |
|
| 2000 |
Watkins LR, Maier SF. The pain of being sick: implications of immune-to-brain communication for understanding pain. Annual Review of Psychology. 51: 29-57. PMID 10751964 DOI: 10.1146/annurev.psych.51.1.29 |
0.607 |
|
| 2000 |
Milligan ED, Mehmert KK, Hinde JL, Harvey LO, Martin D, Tracey KJ, Maier SF, Watkins LR. Thermal hyperalgesia and mechanical allodynia produced by intrathecal administration of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein, gp120. Brain Research. 861: 105-16. PMID 10751570 DOI: 10.1016/S0006-8993(00)02050-3 |
0.718 |
|
| 2000 |
Pugh CR, Johnson JD, Martin D, Rudy JW, Maier SF, Watkins LR. Human immunodeficiency virus-1 coat protein gp120 impairs contextual fear conditioning: a potential role in AIDS related learning and memory impairments. Brain Research. 861: 8-15. PMID 10751560 DOI: 10.1016/S0006-8993(99)02445-2 |
0.479 |
|
| 2000 |
Nguyen KT, Deak T, Will MJ, Hansen MK, Hunsaker BN, Fleshner M, Watkins LR, Maier SF. Timecourse and corticosterone sensitivity of the brain, pituitary, and serum interleukin-1beta protein response to acute stress. Brain Research. 859: 193-201. PMID 10719064 DOI: 10.1016/S0006-8993(99)02443-9 |
0.788 |
|
| 2000 |
Hansen MK, Nguyen KT, Fleshner M, Goehler LE, Gaykema RP, Maier SF, Watkins LR. Effects of vagotomy on serum endotoxin, cytokines, and corticosterone after intraperitoneal lipopolysaccharide. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 278: R331-6. PMID 10666132 DOI: 10.1152/Ajpregu.2000.278.2.R331 |
0.618 |
|
| 2000 |
Maier SF, Watkins LR. The Immune System as a Sensory System Current Directions in Psychological Science. 9: 98-102. DOI: 10.1111/1467-8721.00069 |
0.47 |
|
| 1999 |
Deak T, Nguyen KT, Ehrlich AL, Watkins LR, Spencer RL, Maier SF, Licinio J, Wong ML, Chrousos GP, Webster E, Gold PW. The Impact of the Nonpeptide Corticotropin-Releasing Hormone Antagonist Antalarmin on Behavioral and Endocrine Responses to Stress* *This research was supported by NIMH Grant MH-50479 and the Undergraduate Research Opportunities Program at the University of Colorado at Boulder. Endocrinology. 140: 79-86. PMID 28200658 DOI: 10.1210/endo.140.1.6415 |
0.647 |
|
| 1999 |
Deak T, Nguyen KT, Cotter CS, Fleshner M, Watkins LR, Maier SF, Spencer RL. Long-term changes in mineralocorticoid and glucocorticoid receptor occupancy following exposure to an acute stressor. Brain Research. 847: 211-20. PMID 10575090 DOI: 10.1016/S0006-8993(99)02050-8 |
0.709 |
|
| 1999 |
Milligan ED, Hinde JL, Mehmert KK, Maier SF, Watkins LR. A method for increasing the viability of the external portion of lumbar catheters placed in the spinal subarachnoid space of rats. Journal of Neuroscience Methods. 90: 81-6. PMID 10517276 DOI: 10.1016/S0165-0270(99)00075-8 |
0.649 |
|
| 1999 |
Grahn RE, Maswood S, McQueen MB, Watkins LR, Maier SF. Opioid-dependent effects of inescapable shock on escape behavior and conditioned fear responding are mediated by the dorsal raphe nucleus. Behavioural Brain Research. 99: 153-67. PMID 10512582 DOI: 10.1016/S0166-4328(98)00101-6 |
0.533 |
|
| 1999 |
Hammack SE, Hartley CE, Lea SE, Maier SF, Watkins LR, Sutton LC. Inescapable shock-induced potentiation of morphine analgesia in rats: sites of action. Behavioral Neuroscience. 113: 795-803. PMID 10495087 DOI: 10.1037/0735-7044.113.4.795 |
0.715 |
|
| 1999 |
Deak T, Nguyen KT, Fleshner M, Watkins LR, Maier SF. Acute stress may facilitate recovery from a subcutaneous bacterial challenge. Neuroimmunomodulation. 6: 344-54. PMID 10474053 DOI: 10.1159/000026394 |
0.719 |
|
| 1999 |
Watkins LR, Hansen MK, Nguyen KT, Lee JE, Maier SF. Dynamic regulation of the proinflammatory cytokine, interleukin-1beta: molecular biology for non-molecular biologists. Life Sciences. 65: 449-81. PMID 10462074 DOI: 10.1016/S0024-3205(99)00095-8 |
0.585 |
|
| 1999 |
Maier SF, Nguyen KT, Deak T, Milligan ED, Watkins LR. Stress, learned helplessness, and brain interleukin-1 beta. Advances in Experimental Medicine and Biology. 461: 235-49. PMID 10442176 DOI: 10.1007/978-0-585-37970-8_13 |
0.79 |
|
| 1999 |
Watkins LR, Nguyen KT, Lee JE, Maier SF. Dynamic regulation of proinflammatory cytokines. Advances in Experimental Medicine and Biology. 461: 153-78. PMID 10442173 DOI: 10.1007/978-0-585-37970-8_10 |
0.631 |
|
| 1999 |
Watkins LR, Maier SF. Implications of immune-to-brain communication for sickness and pain. Proceedings of the National Academy of Sciences of the United States of America. 96: 7710-3. PMID 10393885 DOI: 10.1073/pnas.96.14.7710 |
0.584 |
|
| 1999 |
Grahn RE, Will MJ, Hammack SE, Maswood S, McQueen MB, Watkins LR, Maier SF. Activation of serotonin-immunoreactive cells in the dorsal raphe nucleus in rats exposed to an uncontrollable stressor. Brain Research. 826: 35-43. PMID 10216194 DOI: 10.1016/S0006-8993(99)01208-1 |
0.785 |
|
| 1999 |
Goehler LE, Gaykema RP, Nguyen KT, Lee JE, Tilders FJ, Maier SF, Watkins LR. Interleukin-1beta in immune cells of the abdominal vagus nerve: a link between the immune and nervous systems? The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2799-806. PMID 10087091 DOI: 10.1523/Jneurosci.19-07-02799.1999 |
0.608 |
|
| 1999 |
Helmreich DL, Watkins LR, Deak T, Maier SF, Akil H, Watson SJ. The effect of stressor controllability on stress-induced neuropeptide mRNA expression within the paraventricular nucleus of the hypothalamus. Journal of Neuroendocrinology. 11: 121-8. PMID 10048467 DOI: 10.1046/J.1365-2826.1999.00300.X |
0.628 |
|
| 1999 |
Deak T, Nguyen KT, Ehrlich AL, Watkins LR, Spencer RL, Maier SF, Licinio J, Wong ML, Chrousos GP, Webster E, Gold PW. The impact of the nonpeptide corticotropin-releasing hormone antagonist antalarmin on behavioral and endocrine responses to stress. Endocrinology. 140: 79-86. PMID 9886810 DOI: 10.1210/Endo.140.1.6415 |
0.713 |
|
| 1999 |
Goehler LE, Gaykema RPA, Nguyen KT, Lee JE, Tilders FJH, Maier SF, Watkins LR. Interleukin-1β in Immune Cells of the Abdominal Vagus Nerve: a Link between the Immune and Nervous Systems? The Journal of Neuroscience. 19: 2799-2806. DOI: 10.1523/JNEUROSCI.19-07-02799.1999 |
0.541 |
|
| 1999 |
MAIER SF, WATKINS LR. Bidirectional communication between the brain and the immune system: implications for behaviour Animal Behaviour. 57: 741-751. DOI: 10.1006/ANBE.1998.1068 |
0.476 |
|
| 1998 |
Fleshner M, Nguyen KT, Cotter CS, Watkins LR, Maier SF. Acute stressor exposure both suppresses acquired immunity and potentiates innate immunity. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 275: R870-R878. PMID 29586974 DOI: 10.1152/ajpregu.1998.275.3.R870 |
0.564 |
|
| 1998 |
Amat J, Matus-Amat P, Watkins LR, Maier SF. Escapable and inescapable stress differentially alter extracellular levels of 5-HT in the basolateral amygdala of the rat. Brain Research. 812: 113-20. PMID 9813270 DOI: 10.1016/S0006-8993(98)00960-3 |
0.428 |
|
| 1998 |
Milligan ED, Nguyen KT, Deak T, Hinde JL, Fleshner M, Watkins LR, Maier SF. The long term acute phase-like responses that follow acute stressor exposure are blocked by alpha-melanocyte stimulating hormone. Brain Research. 810: 48-58. PMID 9813238 DOI: 10.1016/S0006-8993(98)00869-5 |
0.768 |
|
| 1998 |
Pugh CR, Kumagawa K, Fleshner M, Watkins LR, Maier SF, Rudy JW. Selective effects of peripheral lipopolysaccharide administration on contextual and auditory-cue fear conditioning. Brain, Behavior, and Immunity. 12: 212-29. PMID 9769157 DOI: 10.1006/brbi.1998.0524 |
0.43 |
|
| 1998 |
Goehler LE, Gaykema RP, Hammack SE, Maier SF, Watkins LR. Interleukin-1 induces c-Fos immunoreactivity in primary afferent neurons of the vagus nerve. Brain Research. 804: 306-10. PMID 9757071 DOI: 10.1016/S0006-8993(98)00685-4 |
0.704 |
|
| 1998 |
Gaykema RP, Goehler LE, Tilders FJ, Bol JG, McGorry M, Fleshner M, Maier SF, Watkins LR. Bacterial endotoxin induces fos immunoreactivity in primary afferent neurons of the vagus nerve. Neuroimmunomodulation. 5: 234-40. PMID 9730691 DOI: 10.1159/000026343 |
0.536 |
|
| 1998 |
Fleshner M, Nguyen KT, Cotter CS, Watkins LR, Maier SF. Acute stressor exposure both suppresses acquired immunity and potentiates innate immunity. The American Journal of Physiology. 275: R870-8. PMID 9728086 DOI: 10.1152/Ajpregu.1998.275.3.R870 |
0.605 |
|
| 1998 |
Will MJ, Watkins LR, Maier SF. Uncontrollable stress potentiates morphine's rewarding properties. Pharmacology, Biochemistry, and Behavior. 60: 655-64. PMID 9678649 DOI: 10.1016/S0091-3057(98)00027-6 |
0.706 |
|
| 1998 |
Fleshner M, Goehler LE, Schwartz BA, McGorry M, Martin D, Maier SF, Watkins LR. Thermogenic and corticosterone responses to intravenous cytokines (IL-1beta and TNF-alpha) are attenuated by subdiaphragmatic vagotomy. Journal of Neuroimmunology. 86: 134-41. PMID 9663558 DOI: 10.1016/S0165-5728(98)00026-5 |
0.522 |
|
| 1998 |
Amat J, Matus-Amat P, Watkins LR, Maier SF. Escapable and inescapable stress differentially and selectively alter extracellular levels of 5-HT in the ventral hippocampus and dorsal periaqueductal gray of the rat. Brain Research. 797: 12-22. PMID 9630480 DOI: 10.1016/S0006-8993(98)00368-0 |
0.432 |
|
| 1998 |
Maier SF, Goehler LE, Fleshner M, Watkins LR. The role of the vagus nerve in cytokine-to-brain communication. Annals of the New York Academy of Sciences. 840: 289-300. PMID 9629257 DOI: 10.1111/j.1749-6632.1998.tb09569.x |
0.49 |
|
| 1998 |
Watkins LR, Wiertelak EP, McGorry M, Martinez J, Schwartz B, Sisk D, Maier SF. Neurocircuitry of conditioned inhibition of analgesia: effects of amygdala, dorsal raphe, ventral medullary, and spinal cord lesions on antianalgesia in the rat. Behavioral Neuroscience. 112: 360-78. PMID 9588483 DOI: 10.1037//0735-7044.112.2.360 |
0.749 |
|
| 1998 |
Nguyen KT, Deak T, Owens SM, Kohno T, Fleshner M, Watkins LR, Maier SF. Exposure to acute stress induces brain interleukin-1beta protein in the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2239-46. PMID 9482808 |
0.683 |
|
| 1998 |
Maswood S, Barter JE, Watkins LR, Maier SF. Exposure to inescapable but not escapable shock increases extracellular levels of 5-HT in the dorsal raphe nucleus of the rat. Brain Research. 783: 115-20. PMID 9479059 DOI: 10.1016/S0006-8993(97)01313-9 |
0.454 |
|
| 1998 |
Maier SF, Watkins LR. Cytokines for psychologists: implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition. Psychological Review. 105: 83-107. PMID 9450372 DOI: 10.1037/0033-295X.105.1.83 |
0.484 |
|
| 1998 |
Nguyen KT, Deak T, Owens SM, Kohno T, Fleshner M, Watkins LR, Maier SF. Exposure to Acute Stress Induces Brain Interleukin-1β Protein in the Rat The Journal of Neuroscience. 18: 2239-2246. DOI: 10.1523/Jneurosci.18-06-02239.1998 |
0.705 |
|
| 1998 |
Maier SF, Watkins LR. Stressor controllability, anxiety, and serotonin Cognitive Therapy and Research. 22: 595-613. DOI: 10.1023/A:1018794104325 |
0.454 |
|
| 1997 |
Deak T, Meriwether JL, Fleshner M, Spencer RL, Abouhamze A, Moldawer LL, Grahn RE, Watkins LR, Maier SF. Evidence that brief stress may induce the acute phase response in rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 273: R1998-R2004. PMID 29586945 DOI: 10.1152/ajpregu.1997.273.6.R1998 |
0.408 |
|
| 1997 |
Deak T, Meriwether JL, Fleshner M, Spencer RL, Abouhamze A, Moldawer LL, Grahn RE, Watkins LR, Maier SF. Evidence that brief stress may induce the acute phase response in rats. The American Journal of Physiology. 273: R1998-2004. PMID 9435654 DOI: 10.1152/Ajpregu.1997.273.6.R1998 |
0.645 |
|
| 1997 |
Fleshner M, Silbert L, Deak T, Goehler LE, Martin D, Watkins LR, Maier SF. TNF-alpha-induced corticosterone elevation but not serum protein or corticosteroid binding globulin reduction is vagally mediated. Brain Research Bulletin. 44: 701-6. PMID 9421133 DOI: 10.1016/S0361-9230(97)00258-X |
0.669 |
|
| 1997 |
Sutton LC, Lea SE, Will MJ, Schwartz BA, Hartley CE, Poole JC, Watkins LR, Maier SF. Inescapable shock-induced potentiation of morphine analgesia. Behavioral Neuroscience. 111: 1105-13. PMID 9383528 DOI: 10.1037//0735-7044.111.5.1105 |
0.715 |
|
| 1997 |
Milligan ED, McGorry MM, Fleshner M, Gaykema RP, Goehler LE, Watkins LR, Maier SF. Subdiaphragmatic vagotomy does not prevent fever following intracerebroventricular prostaglandin E2: further evidence for the importance of vagal afferents in immune-to-brain communication. Brain Research. 766: 240-3. PMID 9359608 DOI: 10.1016/S0006-8993(97)00705-1 |
0.682 |
|
| 1997 |
Sutton LC, Grahn RE, Wiertelak EP, Watkins LR, Maier SF. Inescapable shock-induced potentiation of morphine analgesia in rats: involvement of opioid, GABAergic, and serotonergic mechanisms in the dorsal raphe nucleus. Behavioral Neuroscience. 111: 816-24. PMID 9267659 DOI: 10.1037//0735-7044.111.4.816 |
0.75 |
|
| 1997 |
Watkins LR, McGorry M, Schwartz B, Sisk D, Wiertelak EP, Maier SF. Reversal of spinal cord non-opiate analgesia by conditioned anti-analgesia in the rat. Pain. 71: 237-47. PMID 9231866 DOI: 10.1016/S0304-3959(97)03375-7 |
0.742 |
|
| 1997 |
Watkins LR, Martin D, Ulrich P, Tracey KJ, Maier SF. Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat. Pain. 71: 225-35. PMID 9231865 DOI: 10.1016/S0304-3959(97)03369-1 |
0.558 |
|
| 1997 |
Goehler LE, Relton JK, Dripps D, Kiechle R, Tartaglia N, Maier SF, Watkins LR. Vagal paraganglia bind biotinylated interleukin-1 receptor antagonist: a possible mechanism for immune-to-brain communication. Brain Research Bulletin. 43: 357-64. PMID 9227848 DOI: 10.1016/S0361-9230(97)00020-8 |
0.517 |
|
| 1997 |
Wiertelak EP, Roemer B, Maier SF, Watkins LR. Comparison of the effects of nucleus tractus solitarius and ventral medial medulla lesions on illness-induced and subcutaneous formalin-induced hyperalgesias. Brain Research. 748: 143-50. PMID 9067455 DOI: 10.1016/S0006-8993(96)01289-9 |
0.748 |
|
| 1997 |
Watkins LR, Maier SF. The case of the missing brain: Arguments for a role of brain-to-spinal cord pathways in pain facilitation Behavioral and Brain Sciences. 20: 469-470. DOI: 10.1017/S0140525X97561498 |
0.536 |
|
| 1996 |
Grisel JE, Watkins LR, Maier SF. Associative and non-associative mechanisms of morphine analgesic tolerance are neurochemically distinct in the rat spinal cord. Psychopharmacology. 128: 248-55. PMID 8972544 DOI: 10.1007/s002130050132 |
0.54 |
|
| 1996 |
Fleshner M, Brennan FX, Nguyen K, Watkins LR, Maier SF. RU-486 blocks differentially suppressive effect of stress on in vivo anti-KLH immunoglobulin response. The American Journal of Physiology. 271: R1344-52. PMID 8945973 DOI: 10.1152/Ajpregu.1996.271.5.R1344 |
0.599 |
|
| 1996 |
Brennan FX, Cobb CL, Silbert LH, Watkins LR, Maier SF. Peripheral beta-adrenoreceptors and stress-induced hypercholesterolemia in rats. Physiology & Behavior. 60: 1307-10. PMID 8916186 DOI: 10.1016/S0031-9384(96)00255-7 |
0.47 |
|
| 1996 |
Lockwood LL, Silbert LH, Fleshner MR, McNeal C, Watkins LR, Laudenslager ML, Rice KC, Weber RJ, Maier SF. Morphine-induced alterations in antibody levels: receptor and immune mechanisms. The Journal of Pharmacology and Experimental Therapeutics. 278: 689-96. PMID 8768720 |
0.439 |
|
| 1996 |
Brennan FX, Fleshner M, Watkins LR, Maier SF. Macrophage stimulation reduces the cholesterol levels of stressed and unstressed rats. Life Sciences. 58: 1771-6. PMID 8637401 DOI: 10.1016/0024-3205(96)00158-0 |
0.451 |
|
| 1996 |
Maier SF, Watkins LR. Proinflammatory cytokines and specific immune function Pain Forum. 5: 234-236. DOI: 10.1016/S1082-3174(96)80002-X |
0.525 |
|
| 1995 |
Watkins LR, Maier SF, Goehler LE. Immune activation: the role of pro-inflammatory cytokines in inflammation, illness responses and pathological pain states. Pain. 63: 289-302. PMID 8719529 DOI: 10.1016/0304-3959(95)00186-7 |
0.532 |
|
| 1995 |
Maier SF, Watkins LR. Intracerebroventricular interleukin-1 receptor antagonist blocks the enhancement of fear conditioning and interference with escape produced by inescapable shock. Brain Research. 695: 279-82. PMID 8556346 DOI: 10.1016/0006-8993(95)00930-O |
0.516 |
|
| 1995 |
Watkins LR, Goehler LE, Relton J, Brewer MT, Maier SF. Mechanisms of tumor necrosis factor-alpha (TNF-alpha) hyperalgesia. Brain Research. 692: 244-50. PMID 8548310 DOI: 10.1016/0006-8993(95)00715-3 |
0.523 |
|
| 1995 |
Maier SF, Grahn RE, Maswood S, Watkins LR. The benzodiazepine receptor antagonists flumazenil and CGS8216 block the enhancement of fear conditioning and interference with escape behavior produced by inescapable shock. Psychopharmacology. 121: 250-8. PMID 8545531 DOI: 10.1007/BF02245636 |
0.493 |
|
| 1995 |
Grahn RE, Kalman BA, Brennan FX, Watkins LR, Maier SF. The elevated plus-maze is not sensitive to the effect of stressor controllability in rats. Pharmacology, Biochemistry, and Behavior. 52: 565-70. PMID 8545475 DOI: 10.1016/0091-3057(95)00141-I |
0.468 |
|
| 1995 |
Fleshner M, Bellgrau D, Watkins LR, Laudenslager ML, Maier SF. Stress-induced reduction in the rat mixed lymphocyte reaction is due to macrophages and not to changes in T cell phenotypes. Journal of Neuroimmunology. 56: 45-52. PMID 7822481 DOI: 10.1016/0165-5728(94)00132-8 |
0.463 |
|
| 1995 |
Goehler LE, Busch CR, Tartaglia N, Relton J, Sisk D, Maier SF, Watkins LR. Blockade of cytokine induced conditioned taste aversion by subdiaphragmatic vagotomy: further evidence for vagal mediation of immune-brain communication. Neuroscience Letters. 185: 163-6. PMID 7753482 DOI: 10.1016/0304-3940(95)11251-Q |
0.489 |
|
| 1995 |
Watkins LR, Goehler LE, Relton JK, Tartaglia N, Silbert L, Martin D, Maier SF. Blockade of interleukin-1 induced hyperthermia by subdiaphragmatic vagotomy: evidence for vagal mediation of immune-brain communication. Neuroscience Letters. 183: 27-31. PMID 7746479 DOI: 10.1016/0304-3940(94)11105-R |
0.502 |
|
| 1995 |
Fleshner M, Goehler LE, Hermann J, Relton JK, Maier SF, Watkins LR. Interleukin-1 beta induced corticosterone elevation and hypothalamic NE depletion is vagally mediated. Brain Research Bulletin. 37: 605-10. PMID 7670884 DOI: 10.1016/0361-9230(95)00051-F |
0.529 |
|
| 1995 |
Maier SF, Grahn RE, Watkins LR. 8-OH-DPAT microinjected in the region of the dorsal raphe nucleus blocks and reverses the enhancement of fear conditioning and interference with escape produced by exposure to inescapable shock. Behavioral Neuroscience. 109: 404-12. PMID 7662151 DOI: 10.1037//0735-7044.109.3.404 |
0.479 |
|
| 1995 |
Watkins LR, Maier SF, Goehler LE. Cytokine-to-brain communication: a review & analysis of alternative mechanisms. Life Sciences. 57: 1011-26. PMID 7658909 DOI: 10.1016/0024-3205(95)02047-M |
0.479 |
|
| 1995 |
Fleshner M, Deak T, Spencer RL, Laudenslager ML, Watkins LR, Maier SF. A long-term increase in basal levels of corticosterone and a decrease in corticosteroid-binding globulin after acute stressor exposure. Endocrinology. 136: 5336-42. PMID 7588279 DOI: 10.1210/Endo.136.12.7588279 |
0.643 |
|
| 1995 |
Maier SF, Busch CR, Maswood S, Grahn RE, Watkins LR. The dorsal raphe nucleus is a site of action mediating the behavioral effects of the benzodiazepine receptor inverse agonist DMCM. Behavioral Neuroscience. 109: 759-66. PMID 7576219 DOI: 10.1037/0735-7044.109.4.759 |
0.504 |
|
| 1995 |
Fleshner M, Hermann J, Lockwood LL, Laudenslager ML, Watkins LR, Maier SF. Stressed rats fail to expand the CD45RC+CD4+ (Th1-like) T cell subset in response to KLH: possible involvement of IFN-gamma. Brain, Behavior, and Immunity. 9: 101-12. PMID 7549034 DOI: 10.1006/brbi.1995.1011 |
0.48 |
|
| 1994 |
Watkins LR, Wiertelak EP, Goehler LE, Mooney-Heiberger K, Martinez J, Furness L, Smith KP, Maier SF. Neurocircuitry of illness-induced hyperalgesia. Brain Research. 639: 283-99. PMID 8205482 DOI: 10.1016/0006-8993(94)91742-6 |
0.758 |
|
| 1994 |
Wiertelak EP, Yang HY, Mooney-Heiberger K, Maier SF, Watkins LR. The nature of conditioned anti-analgesia: spinal cord opiate and anti-opiate neurochemistry. Brain Research. 634: 214-26. PMID 8131071 DOI: 10.1016/0006-8993(94)91924-0 |
0.774 |
|
| 1994 |
Wiertelak EP, Smith KP, Furness L, Mooney-Heiberger K, Mayr T, Maier SF, Watkins LR. Acute and conditioned hyperalgesic responses to illness. Pain. 56: 227-34. PMID 8008412 DOI: 10.1016/0304-3959(94)90098-1 |
0.77 |
|
| 1994 |
Lockwood LL, Silbert LH, Fleshner M, Laudenslager ML, Watkins LR, Maier SF. Morphine-induced decreases in in vivo antibody responses. Brain, Behavior, and Immunity. 8: 24-36. PMID 8003769 DOI: 10.1006/brbi.1994.1003 |
0.512 |
|
| 1994 |
Watkins LR, Wiertelak EP, Goehler LE, Smith KP, Martin D, Maier SF. Characterization of cytokine-induced hyperalgesia. Brain Research. 654: 15-26. PMID 7982088 DOI: 10.1016/0006-8993(94)91566-0 |
0.768 |
|
| 1994 |
Wiertelak EP, Furness LE, Horan R, Martinez J, Maier SF, Watkins LR. Subcutaneous formalin produces centrifugal hyperalgesia at a non-injected site via the NMDA-nitric oxide cascade. Brain Research. 649: 19-26. PMID 7953632 DOI: 10.1016/0006-8993(94)91044-8 |
0.767 |
|
| 1994 |
Wiertelak EP, Furness LE, Watkins LR, Maier SF. Illness-induced hyperalgesia is mediated by a spinal NMDA-nitric oxide cascade. Brain Research. 664: 9-16. PMID 7895051 DOI: 10.1016/0006-8993(94)91947-X |
0.767 |
|
| 1994 |
Grisel JE, Wiertelak EP, Watkins LR, Maier SF. Route of morphine administration modulates conditioned analgesic tolerance and hyperalgesia. Pharmacology, Biochemistry, and Behavior. 49: 1029-35. PMID 7886072 DOI: 10.1016/0091-3057(94)90260-7 |
0.741 |
|
| 1994 |
Sutton LC, Fleshner M, Mazzeo R, Maier SF, Watkins LR. A permissive role of corticosterone in an opioid form of stress-induced analgesia: blockade of opiate analgesia is not due to stress-induced hormone release. Brain Research. 663: 19-29. PMID 7850467 DOI: 10.1016/0006-8993(94)90458-8 |
0.554 |
|
| 1994 |
Maier SF, Watkins LR, Fleshner M. Psychoneuroimmunology. The interface between behavior, brain, and immunity. The American Psychologist. 49: 1004-17. PMID 7818221 DOI: 10.1037//0003-066x.49.12.1004 |
0.479 |
|
| 1994 |
Watkins LR, Wiertelak EP, Furness LE, Maier SF. Illness-induced hyperalgesia is mediated by spinal neuropeptides and excitatory amino acids. Brain Research. 664: 17-24. PMID 7534600 DOI: 10.1016/0006-8993(94)91948-8 |
0.752 |
|
| 1993 |
Grisel JE, Fleshner M, Watkins LR, Maier SF. Opioid and nonopioid interactions in two forms of stress-induced analgesia. Pharmacology, Biochemistry, and Behavior. 45: 161-72. PMID 8516354 DOI: 10.1016/0091-3057(93)90100-8 |
0.554 |
|
| 1993 |
Watkins LR, Wiertelak EP, Maier SF. The amygdala is necessary for the expression of conditioned but not unconditioned analgesia. Behavioral Neuroscience. 107: 402-5. PMID 8484903 DOI: 10.1037//0735-7044.107.2.402 |
0.71 |
|
| 1993 |
Maier SF, Grahn RE, Kalman BA, Sutton LC, Wiertelak EP, Watkins LR. The role of the amygdala and dorsal raphe nucleus in mediating the behavioral consequences of inescapable shock. Behavioral Neuroscience. 107: 377-88. PMID 8484901 DOI: 10.1037//0735-7044.107.2.377 |
0.71 |
|
| 1993 |
Fleshner M, Watkins LR, Lockwood LL, Grahn RE, Gerhardt G, Meaney MJ, Laudenslager ML, Maier SF. Blockade of the hypothalamic-pituitary-adrenal response to stress by intraventricular injection of dexamethasone: a method for studying the stress-induced peripheral effects of glucocorticoids. Psychoneuroendocrinology. 18: 251-63. PMID 8391148 DOI: 10.1016/0306-4530(93)90022-D |
0.472 |
|
| 1993 |
Fleshner M, Brohm MM, Laudenslager ML, Watkins LR, Maier SF. Modulation of the in vivo antibody response by a benzodiazepine inverse agonist (DMCM) administered centrally or peripherally. Physiology & Behavior. 54: 1149-54. PMID 8295955 DOI: 10.1016/0031-9384(93)90339-H |
0.49 |
|
| 1993 |
Maier SF, Wiertelak EP, Martin D, Watkins LR. Interleukin-1 mediates the behavioral hyperalgesia produced by lithium chloride and endotoxin. Brain Research. 623: 321-4. PMID 8221116 DOI: 10.1016/0006-8993(93)91446-Y |
0.736 |
|
| 1993 |
Lockwood LL, Silbert LH, Laudenslager ML, Watkins LR, Maier SF. Anesthesia-induced modulation of in vivo antibody levels: a study of pentobarbital, chloral hydrate, methoxyflurane, halothane, and ketamine/xylazine. Anesthesia and Analgesia. 77: 769-74. PMID 8214663 DOI: 10.1213/00000539-199310000-00020 |
0.443 |
|
| 1993 |
Fleshner M, Watkins LR, Lockwood LL, Bellgrau D, Laudenslager ML, Maier SF. Specific changes in lymphocyte subpopulations: a potential mechanism for stress-induced immunomodulation. Journal of Neuroimmunology. 41: 131-42. PMID 1469075 DOI: 10.1016/0165-5728(92)90063-Q |
0.458 |
|
| 1992 |
Wiertelak EP, Maier SF, Watkins LR. Cholecystokinin antianalgesia: safety cues abolish morphine analgesia. Science (New York, N.Y.). 256: 830-3. PMID 1589765 DOI: 10.1126/Science.256.5058.830 |
0.759 |
|
| 1992 |
Brennan FX, Job RF, Watkins LR, Maier SF. Total plasma cholesterol levels of rats are increased following only three sessions of tailshock. Life Sciences. 50: 945-50. PMID 1548978 DOI: 10.1016/0024-3205(92)90172-L |
0.421 |
|
| 1992 |
Thurston CL, Campbell IG, Culhane ES, Carstens E, Watkins LR. Characterization of intrathecal vasopressin-induced antinociception, scratching behavior, and motor suppression Peptides. 13: 17-25. PMID 1535707 DOI: 10.1016/0196-9781(92)90135-P |
0.377 |
|
| 1992 |
Douglass DK, Carstens E, Watkins LR. Spatial summation in human thermal pain perception: comparison within and between dermatomes. Pain. 50: 197-202. PMID 1408316 DOI: 10.1016/0304-3959(92)90161-4 |
0.327 |
|
| 1992 |
Watkins LR, Wiertelak EP, Maier SF. Kappa opiate receptors mediate tail-shock induced antinociception at spinal levels. Brain Research. 582: 1-9. PMID 1354010 DOI: 10.1016/0006-8993(92)90310-6 |
0.772 |
|
| 1992 |
Watkins LR, Wiertelak EP, Grisel JE, Silbert LH, Maier SF. Parallel activation of multiple spinal opiate systems appears to mediate 'non-opiate' stress-induced analgesias. Brain Research. 594: 99-108. PMID 1334766 DOI: 10.1016/0006-8993(92)91033-B |
0.777 |
|
| 1992 |
Watkins LR, Wiertelak EP, Maier SF. Delta opiate receptors mediate tail-shock induced antinociception at supraspinal levels. Brain Research. 582: 10-21. PMID 1323369 DOI: 10.1016/0006-8993(92)90311-V |
0.745 |
|
| 1992 |
Wiertelak EP, Watkins LR, Maier SF. Conditioned inhibition of analgesia Animal Learning & Behavior. 20: 339-349. DOI: 10.3758/Bf03197957 |
0.75 |
|
| 1992 |
WATKINS LR, WIERTELAK EP, MAIER F. BEHAVIORAL EVIDENCE FOR THE EXISTENCE OF ???ANTI-ANALGESIA??? SYSTEMS Behavioural Pharmacology. 3: 102. DOI: 10.1097/00008877-199204001-00315 |
0.628 |
|
| 1992 |
Maier SF, Wiertelak EP, Watkins LR. Commentary on the commentaries Aps Journal. 1: 210-211. DOI: 10.1016/1058-9139(92)90013-3 |
0.668 |
|
| 1992 |
Maier SF, Wiertelak EP, Watkins LR. Endogenous pain facilitory systems Antianalgesia and hyperalgesia Aps Journal. 1: 191-198. DOI: 10.1016/1058-9139(92)90009-2 |
0.768 |
|
| 1991 |
Campbell IG, Carstens E, Watkins LR. Comparison of human pain sensation and flexion withdrawal evoked by noxious radiant heat Pain. 45: 259-268. PMID 1876435 DOI: 10.1016/0304-3959(91)90050-8 |
0.378 |
|
| 1991 |
Maier SF, Watkins LR. Conditioned and unconditioned stress-induced analgesia: Stimulus preexposure and stimulus change Animal Learning &Amp; Behavior. 19: 295-304. DOI: 10.3758/BF03197890 |
0.466 |
|
| 1990 |
Watkins LR, Thurston CL, Fleshner M. Phenylephrine-induced antinociception: investigations of potential neural and endocrine bases Brain Research. 528: 273-284. PMID 2271928 DOI: 10.1016/0006-8993(90)91668-7 |
0.378 |
|
| 1989 |
Guinan MJ, Rothfeld JM, Pretel S, Culhane ES, Carstens E, Watkins LR. Electrical stimulation of the rat ventral midbrain elicits antinociception via the dorsolateral funiculus. Brain Research. 485: 333-48. PMID 2720418 DOI: 10.1016/0006-8993(89)90578-7 |
0.347 |
|
| 1988 |
Klatt DS, Guinan MJ, Culhane ES, Carstens E, Watkins LR. The dorsal raphe nucleus: a re-evaluation of its proposed role in opiate analgesia systems. Brain Research. 447: 246-52. PMID 3390696 DOI: 10.1016/0006-8993(88)91126-2 |
0.342 |
|
| 1988 |
Thurston CL, Culhane ES, Suberg SN, Carstens E, Watkins LR. Antinociception vs motor effects of intrathecal vasopressin as measured by four pain tests Brain Research. 463: 1-11. PMID 3196898 DOI: 10.1016/0006-8993(88)90520-3 |
0.367 |
|
| 1987 |
Thurston CL, Culhane ES, Carstens E, Watkins LR. Intrathecal vasopressin induced tail flick suppression Pain. 30: S37. DOI: 10.1016/0304-3959(87)91152-3 |
0.338 |
|
| 1986 |
Watkins LR, Suberg SN, Thurston CL, Culhane ES. Role of spinal cord neuropeptides in pain sensitivity and analgesia: Thyrotropin releasing hormone and vasopressin Brain Research. 362: 308-317. PMID 3080201 DOI: 10.1016/0006-8993(86)90455-5 |
0.447 |
|
| 1986 |
Watkins LR, Mayer DJ. Multiple endogenous opiate and non-opiate analgesia systems: evidence of their existence and clinical implications. Annals of the New York Academy of Sciences. 467: 273-99. PMID 3014973 DOI: 10.1111/J.1749-6632.1986.Tb14635.X |
0.548 |
|
| 1985 |
Ryan SM, Watkins LR, Mayer DJ, Maier SF. Spinal pain suppression mechanisms may differ for phasic and tonic pain. Brain Research. 334: 172-5. PMID 3995310 DOI: 10.1016/0006-8993(85)90582-7 |
0.711 |
|
| 1985 |
Watkins LR, Kinscheck IB, Kaufman EF, Miller J, Frenk H, Mayer DJ. Cholecystokinin antagonists selectively potentiate analgesia induced by endogenous opiates. Brain Research. 327: 181-90. PMID 3838691 DOI: 10.1016/0006-8993(85)91512-4 |
0.621 |
|
| 1985 |
Watkins LR, Kinscheck IB, Mayer DJ. Potentiation of morphine analgesia by the cholecystokinin antagonist proglumide. Brain Research. 327: 169-80. PMID 3838690 DOI: 10.1016/0006-8993(85)91511-2 |
0.644 |
|
| 1985 |
WATKINS LR, KINSCHECK IB, ROSENQUIST G, MILLER J, WIMBERG S, FRENK H, KAUFMAN E, COGHILL R, SUBERG SN, MAYER DJ. The Enhancement of Opiate Analgesia and the Possible Reversal of Morphine Tolerance by Proglumidea Annals of the New York Academy of Sciences. 448: 676-677. DOI: 10.1111/J.1749-6632.1985.TB29986.X |
0.713 |
|
| 1985 |
Suberg SN, Culhane ES, Carstens E, Watkins LR. The potentiation of morphine-induced inhibition of spinal transmission by proglumide, a putative cholecystokinin antagonist Annals of the New York Academy of Sciences. 660-662. DOI: 10.1111/J.1749-6632.1985.Tb29980.X |
0.372 |
|
| 1985 |
Katayama Y, Watkins LR, Becker DP, Hayes RL. Non-opiate analgesia induced by carbachol microinjection into the pontine parabrachial region of the cat Pain. 22: 207-208. DOI: 10.1016/0304-3959(85)90188-5 |
0.314 |
|
| 1985 |
Watkins LR, Katayama Y, Kinscheck IB, Mayer DJ, Hayes RL. Muscarinic cholinergic mediation of opiate and non-opiate environmentally induced analgesias Pain. 23: 310. DOI: 10.1016/0304-3959(85)90125-3 |
0.59 |
|
| 1984 |
Watkins LR, Katayama Y, Kinscheck IB, Mayer DJ, Hayes RL. Muscarinic cholinergic mediation of opiate and non-opiate environmentally induced analgesias. Brain Research. 300: 231-42. PMID 6733471 DOI: 10.1016/0006-8993(84)90834-5 |
0.611 |
|
| 1984 |
Kinscheck IB, Watkins LR, Mayer DJ. Fear is not critical to classically conditioned analgesia: the effects of periaqueductal gray lesions and administration of chlordiazepoxide. Brain Research. 298: 33-44. PMID 6722557 DOI: 10.1016/0006-8993(84)91144-2 |
0.567 |
|
| 1984 |
Watkins LR, Faris PL, Komisaruk BR, Mayer DJ. Dorsolateral funiculus and intraspinal pathways mediate vaginal stimulation-induced suppression of nociceptive responding in rats. Brain Research. 294: 59-65. PMID 6697242 DOI: 10.1016/0006-8993(84)91309-X |
0.61 |
|
| 1984 |
Watkins LR, Drugan R, Hyson RL, Moye TB, Ryan SM, Mayer DJ, Maier SF. Opiate and non-opiate analgesia induced by inescapable tail-shock: effects of dorsolateral funiculus lesions and decerebration. Brain Research. 291: 325-36. PMID 6697193 DOI: 10.1016/0006-8993(84)91265-4 |
0.685 |
|
| 1984 |
Young EG, Watkins LR, Mayer DJ. Comparison of the effects of ventral medullary lesions on systemic and microinjection morphine analgesia. Brain Research. 290: 119-29. PMID 6692127 DOI: 10.1016/0006-8993(84)90741-8 |
0.568 |
|
| 1984 |
Watkins LR, Johannessen JN, Kinscheck IB, Mayer DJ. The neurochemical basis of footshock analgesia: the role of spinal cord serotonin and norepinephrine. Brain Research. 290: 107-17. PMID 6692126 DOI: 10.1016/0006-8993(84)90740-6 |
0.57 |
|
| 1984 |
Watkins LR, Frenk H, Miller J, Mayer DJ. Effect of spinal cord lesions on convulsive activity induced by intrathecal morphine. Brain Research. 310: 337-45. PMID 6548400 DOI: 10.1016/0006-8993(84)90156-2 |
0.579 |
|
| 1984 |
Watkins LR, Kinscheck IB, Mayer DJ. Potentiation of opiate analgesia and apparent reversal of morphine tolerance by proglumide. Science (New York, N.Y.). 224: 395-6. PMID 6546809 DOI: 10.1126/Science.6546809 |
0.608 |
|
| 1984 |
Hayes RL, Katayama Y, Watkins LR, Becker DP. Bilateral lesions of the dorsolateral funiculus of the cat spinal cord: Effects on basal nociceptive reflexes and nociceptive suppression produced by cholinergic activation of the pontine parabrachial region Brain Research. 311: 267-280. PMID 6498485 DOI: 10.1016/0006-8993(84)90089-1 |
0.352 |
|
| 1984 |
Katayama Y, Watkins LR, Becker DP, Hayes RL. Evidence for involvement of cholinoceptive cells of the parabrachial region in environmentally induced nociceptive suppression in the cat Brain Research. 299: 348-353. PMID 6329422 DOI: 10.1016/0006-8993(84)90717-0 |
0.335 |
|
| 1984 |
Frenk H, Watkins LR, Miller J, Mayer DJ. Nonspecific convulsions are induced by morphine but not D-Ala2-methionine-enkephalinamide at cortical sites. Brain Research. 299: 51-9. PMID 6326965 DOI: 10.1016/0006-8993(84)90787-X |
0.575 |
|
| 1984 |
Watkins LR, Frenk H, Miller J, Mayer DJ. Cataleptic effects of opiates following intrathecal administration. Brain Research. 299: 43-9. PMID 6326964 DOI: 10.1016/0006-8993(84)90786-8 |
0.597 |
|
| 1984 |
Frenk H, Watkins LR, Mayer DJ. Differential behavioral effects induced by intrathecal microinjection of opiates: comparison of convulsive and cataleptic effects produced by morphine, methadone, and D-Ala2-methionine-enkephalinamide. Brain Research. 299: 31-42. PMID 6326963 DOI: 10.1016/0006-8993(84)90785-6 |
0.616 |
|
| 1984 |
Katayama Y, Watkins LR, Becker DP, Hayes RL. Non-opiate analgesia induced by carbachol microinjection into the pontine parabrachial region of the cat Brain Research. 296: 263-283. PMID 6322925 DOI: 10.1016/0006-8993(84)90063-5 |
0.438 |
|
| 1984 |
Price DD, Rafii A, Watkins LR, Buckingham B. A psychophysical analysis of acupuncture analgesia Pain. 19: 27-42. PMID 6234501 DOI: 10.1016/0304-3959(84)90062-9 |
0.414 |
|
| 1984 |
Johannessen JN, Watkins LR, Mayer DJ. Non-serotonergic origins of the dorsolateral funiculus in the rat ventral medulla. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 757-66. PMID 6200581 DOI: 10.1523/Jneurosci.04-03-00757.1984 |
0.584 |
|
| 1984 |
Watkins L, Kinscheck I, Miller J, Coghill R, Frank H, Mayer D. CCK antagonists enhance opiate analgesia & appear to reverse morphine tolerance Pain. 18: S353. DOI: 10.1016/0304-3959(84)90659-6 |
0.716 |
|
| 1983 |
Lewis JW, Terman GW, Watkins LR, Mayer DJ, Liebeskind JC. Opioid and non-opioid mechanisms of footshock-induced analgesia: role of the spinal dorsolateral funiculus. Brain Research. 267: 139-44. PMID 6860939 DOI: 10.1016/0006-8993(83)91047-8 |
0.734 |
|
| 1983 |
Watkins LR, Kinscheck IB, Mayer DJ. The neural basis of footshock analgesia: the effect of periaqueductal gray lesions and decerebration. Brain Research. 276: 317-24. PMID 6627012 DOI: 10.1016/0006-8993(83)90739-4 |
0.643 |
|
| 1983 |
Watkins LR, Young EG, Kinscheck IB, Mayer DJ. The neural basis of footshock analgesia: the role of specific ventral medullary nuclei. Brain Research. 276: 305-15. PMID 6627011 DOI: 10.1016/0006-8993(83)90738-2 |
0.621 |
|
| 1983 |
Faris PL, Komisaruk BR, Watkins LR, Mayer DJ. Evidence for the neuropeptide cholecystokinin as an antagonist of opiate analgesia. Science (New York, N.Y.). 219: 310-2. PMID 6294831 DOI: 10.1126/Science.6294831 |
0.613 |
|
| 1982 |
Watkins LR, Cobelli DA, Mayer DJ. Opiate vs non-opiate footshock induced analgesia (FSIA): descending and intraspinal components. Brain Research. 245: 97-106. PMID 7116195 DOI: 10.1016/0006-8993(82)90342-0 |
0.623 |
|
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