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Year Citation  Score
2016 Rudensky AY, Preston-Hurlburt P, Hong SC, Barlow A, Janeway CA. Pillars Article: Sequence Analysis of Peptides Bound to MHC Class II Molecules. Nature. 1991. 353: 622-627. Journal of Immunology (Baltimore, Md. : 1950). 196: 941-6. PMID 26802059  0.64
2016 Rudensky AY, Preston-Hurlburt P, Hong SC, Barlow A, Janeway CA. Sequence analysis of peptides bound to MHC class II molecules Journal of Immunology. 196: 941-946.  0.36
2013 Janeway CA. Pillars article: approaching the asymptote? Evolution and revolution in immunology. Cold spring harb symp quant biol. 1989. 54: 1-13. Journal of Immunology (Baltimore, Md. : 1950). 191: 4475-87. PMID 24141854  1
2008 Eichmann K, Avery OT, Baltimore D, Von Behring E, Benacerraf B, Bloor D, Bordet JJBV, Bona CA, Boyse EA, Burnet FM, Cantor H, Cazenave PA, Claman HN, Cohn M, Coutinho A, ... ... Janeway CA, et al. The network collective: Rise and fall of a scientific paradigm The Network Collective: Rise and Fall of a Scientific Paradigm. 1-274. DOI: 10.1007/978-3-7643-8373-2  1
2005 Bynoe MS, Viret C, Flavell RA, Janeway CA. T cells from epicutaneously immunized mice are prone to T cell receptor revision. Proceedings of the National Academy of Sciences of the United States of America. 102: 2898-903. PMID 15708975 DOI: 10.1073/pnas.0409880102  1
2004 Munier AI, Medzhitov R, Janeway CA, Doucet D, Capovilla M, Lagueux M. graal: a Drosophila gene coding for several mosaic serine proteases. Insect Biochemistry and Molecular Biology. 34: 1025-35. PMID 15475297 DOI: 10.1016/j.ibmb.2003.09.009  1
2004 Wong FS, Wen L, Tang M, Ramanathan M, Visintin I, Daugherty J, Hannum LG, Janeway CA, Shlomchik MJ. Investigation of the role of B-cells in type 1 diabetes in the NOD mouse. Diabetes. 53: 2581-7. PMID 15448087 DOI: 10.2337/diabetes.53.10.2581  1
2003 Bynoe MS, Evans JT, Viret C, Janeway CA. Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis. Immunity. 19: 317-28. PMID 14499108 DOI: 10.1016/S1074-7613(03)00239-5  1
2003 Viret C, He X, Janeway CA. Altered positive selection due to corecognition of floppy peptide/MHC II conformers supports an integrative model of thymic selection. Proceedings of the National Academy of Sciences of the United States of America. 100: 5354-9. PMID 12700352 DOI: 10.1073/pnas.0831129100  1
2003 Blander JM, Sant'Angelo DB, Metz D, Kim SW, Flavell RA, Bottomly K, Janeway CA. A pool of central memory-like CD4 T cells contains effector memory precursors. Journal of Immunology (Baltimore, Md. : 1950). 170: 2940-8. PMID 12626545  1
2003 Das G, Janeway CA. MHC specificity of iIELs. Trends in Immunology. 24: 88-93. PMID 12547506 DOI: 10.1016/S1471-4906(02)00036-4  1
2003 King WJ, MacKay M, Sirnick A, Morris R, Janeway CA, Anderson J, Fortin G, Chauvin-Kimoff L, Bennett S, Mian M, MacMillan H, Lindsay D, McKenna A, Anderson L, Hlady J. Shaken baby syndrome in Canada: Clinical characteristics and outcomes of hospital cases Cmaj. 168: 155-159. PMID 12538542  1
2003 Viret C, Janeway CA. Self-specific MHC class II-restricted CD4-CD8- T cells that escape deletion and lack regulatory activity. Journal of Immunology (Baltimore, Md. : 1950). 170: 201-9. PMID 12496401  1
2002 Munier AI, Doucet D, Perrodou E, Zachary D, Meister M, Hoffmann JA, Janeway CA, Lagueux M. PVF2, a PDGF/VEGF-like growth factor, induces hemocyte proliferation in Drosophila larvae. Embo Reports. 3: 1195-200. PMID 12446570 DOI: 10.1093/embo-reports/kvf242  1
2002 Holcombe H, Mellman I, Janeway CA, Bottomly K, Dittel BN. The immunosuppressive agent 15-deoxyspergualin functions by inhibiting cell cycle progression and cytokine production following naive T cell activation. Journal of Immunology (Baltimore, Md. : 1950). 169: 4982-9. PMID 12391212  1
2002 Grewal IS, Grewal KD, Wong FS, Wang H, Picarella DE, Janeway CA, Flavell RA. Expression of transgene encoded TGF-beta in islets prevents autoimmune diabetes in NOD mice by a local mechanism. Journal of Autoimmunity. 19: 9-22. PMID 12367555 DOI: 10.1006/jaut.2002.0599  1
2002 He X, Viret C, Janeway CA. Self-recognition and the biased mature repertoire in TCR beta transgenic mice: the exception that supports the rule. Trends in Immunology. 23: 467-9. PMID 12297410 DOI: 10.1016/S1471-4906(02)02306-2  1
2002 Sant'Angelo DB, Robinson E, Janeway CA, Denzin LK. Recognition of core and flanking amino acids of MHC class II-bound peptides by the T cell receptor. European Journal of Immunology. 32: 2510-20. PMID 12207335 DOI: 10.1002/1521-4141(200209)32:9<2510::AID-IMMU2510>3.0.CO;2-Q  1
2002 Carrithers MD, Visintin I, Viret C, Janeway CS. Role of genetic background in P selectin-dependent immune surveillance of the central nervous system. Journal of Neuroimmunology. 129: 51-7. PMID 12161020 DOI: 10.1016/S0165-5728(02)00172-8  1
2002 Kobayashi K, Hernandez LD, Galán JE, Janeway CA, Medzhitov R, Flavell RA. IRAK-M is a negative regulator of Toll-like receptor signaling. Cell. 110: 191-202. PMID 12150927 DOI: 10.1016/S0092-8674(02)00827-9  1
2002 Sant'Angelo DB, Janeway CA. Negative selection of thymocytes expressing the D10 TCR. Proceedings of the National Academy of Sciences of the United States of America. 99: 6931-6. PMID 12011450 DOI: 10.1073/pnas.102182499  1
2002 Medzhitov R, Janeway CA. Decoding the patterns of self and nonself by the innate immune system. Science (New York, N.Y.). 296: 298-300. PMID 11951031 DOI: 10.1126/science.1068883  1
2002 Wong FS, Moustakas AK, Wen L, Papadopoulos GK, Janeway CA. Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K(d) that stimulates CD8 T cells in insulin-dependent diabetes mellitus. Proceedings of the National Academy of Sciences of the United States of America. 99: 5551-6. PMID 11943852 DOI: 10.1073/pnas.072037299  1
2002 Kobayashi K, Inohara N, Hernandez LD, Galán JE, Núñez G, Janeway CA, Medzhitov R, Flavell RA. RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature. 416: 194-9. PMID 11894098 DOI: 10.1038/416194a  1
2002 Janeway CA, Medzhitov R. Innate immune recognition. Annual Review of Immunology. 20: 197-216. PMID 11861602 DOI: 10.1146/annurev.immunol.20.083001.084359  1
2002 Janeway CA. A trip through my life with an immunological theme. Annual Review of Immunology. 20: 1-28. PMID 11861595 DOI: 10.1146/annurev.immunol.20.080801.102422  1
2002 Sankaran K, Chien LY, Walker R, Seshia M, Ohlsson A. Variations in mortality rates among Canadian neonatal intensive care units. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 166: 173-8. PMID 11826939  1
2002 He X, Janeway CA, Levine M, Robinson E, Preston-Hurlburt P, Viret C, Bottomly K. Dual receptor T cells extend the immune repertoire for foreign antigens. Nature Immunology. 3: 127-34. PMID 11812989 DOI: 10.1038/ni751  1
2001 Janeway CA. How the immune system protects the host from infection Microbes and Infection. 3: 1167-1171. PMID 11709297 DOI: 10.1016/S1286-4579(01)01477-0  1
2001 Viret C, He X, Janeway CA. Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptide Proceedings of the National Academy of Sciences of the United States of America. 98: 9243-9248. PMID 11470911 DOI: 10.1073/pnas.161274698  1
2001 Sant'Angelo DB, Cresswell P, Janeway CA, Denzin LK. Maintenance of TCR clonality in T cells expressing genes for two TCR heterodimers. Proceedings of the National Academy of Sciences of the United States of America. 98: 6824-9. PMID 11381132 DOI: 10.1073/pnas.121179998  1
2001 Grewal IS, Foellmer HG, Grewal KD, Wang H, Lee WP, Tumas D, Janeway CA, Flavell RA. CD62L is required on effector cells for local interactions in the CNS to cause myelin damage in experimental allergic encephalomyelitis Immunity. 14: 291-302. PMID 11290338 DOI: 10.1016/S1074-7613(01)00110-8  1
2000 Medzhitov R, Janeway C. Fly immunity: great expectations Genome Biology. 1: REVIEWS106. PMID 11104525  1
2000 Buonfiglio D, Bragardo M, Redoglia V, Vaschetto R, Bottarel F, Bonissoni S, Bensi T, Mezzatesta C, Janeway CA, Dianzani U. The T cell activation molecule H4 and the CD28-like molecule ICOS are identical European Journal of Immunology. 30: 3463-3467. PMID 11093165 DOI: 10.1002/1521-4141(2000012)30:12<3463::AID-IMMU3463>3.0.CO;2-5  1
2000 Das G, Gould DS, Augustine MM, Fragoso G, Sciutto E, Stroynowski I, Van Kaer L, Schust DJ, Ploegh H, Janeway CA. Qa-2-dependent selection of CD8α/α T cell receptor α/β+ cells in murine intestinal intraepithelial lymphocytes Journal of Experimental Medicine. 192: 1521-1527. PMID 11085754 DOI: 10.1084/jem.192.10.1521  1
2000 Medzhitov R, Janeway C. The Toll receptor family and microbial recognition. Trends in Microbiology. 8: 452-6. PMID 11044679 DOI: 10.1016/S0966-842X(00)01845-X  1
2000 Janeway C, Medzhitov R. Viral interference with IL-1 and toll signaling. Proceedings of the National Academy of Sciences of the United States of America. 97: 10682-3. PMID 11005852  1
2000 Medzhitov R, Janeway C. Innate immunity. The New England Journal of Medicine. 343: 338-44. PMID 10922424 DOI: 10.1056/NEJM200008033430506  1
2000 Medzhitov R, Janeway CA. How does the immune system distinguish self from nonself? Seminars in Immunology. 12: 185-8; discussion 25. PMID 10910738 DOI: 10.1006/smim.2000.0230  1
2000 Dittel BN, Urbania TH, Janeway CA. Relapsing and remitting experimental autoimmune encephalomyelitis in B cell deficient mice Journal of Autoimmunity. 14: 311-318. PMID 10882057 DOI: 10.1006/jaut.2000.0371  1
2000 Blander JM, Sant'Angelo DB, Bottomly K, Janeway CA. Alteration at a single amino acid residue in the T cell receptor alpha chain complementarity determining region 2 changes the differentiation of naive CD4 T cells in response to antigen from T helper cell type 1 (Th1) to Th2. The Journal of Experimental Medicine. 191: 2065-74. PMID 10859331 DOI: 10.1084/jem.191.12.2065  1
2000 Carrithers MD, Visintin I, Kang SJ, Janeway CA. Differential adhesion molecule requirements for immune surveillance and inflammatory recruitment Brain. 123: 1092-1101. PMID 10825349  1
2000 Criado G, Feito MJ, Ojeda G, Sánchez A, Janeway CA, Portolés P, Rojo JM. Variability of invariant mouse CD3ε chains detected by anti-CD3 antibodies European Journal of Immunology. 30: 1469-1479. PMID 10820395 DOI: 10.1002/(SICI)1521-4141(200005)30:5<1469::AID-IMMU1469>3.0.CO;2-V  1
2000 Viret C, Barlow AK, Janeway CA. Polymorphism of the mouse T-cell receptor AV20S1 gene Immunogenetics. 51: 392-394. PMID 10803855  1
2000 Viret C, Janeway CA. Functional and phenotypic evidence for presentation of Eα52-68 structurally related self-peptide(s) in I-Eα-deficient mice Journal of Immunology. 164: 4627-4634. PMID 10779766  1
2000 Lucia MB, Buonfiglio D, Bottarel F, Bensi T, Rutella S, Rumi C, Ortona L, Janeway CA, Cauda R, Dianzani U. Expression of the novel T cell activation molecule hpH4 in HIV-infected patients: Correlation with disease status Aids Research and Human Retroviruses. 16: 549-557. PMID 10777145 DOI: 10.1089/088922200308963  1
2000 McInerney MF, Burkey J, Guan L, Flynn JC, Oravecz KI, Janeway CA. An islet-specific CD8+ T cell hybridoma generated from non-obese diabetic mice recognizes insulin as an autoantigen. Diabetes Research and Clinical Practice. 47: 151-68. PMID 10741564 DOI: 10.1016/S0168-8227(99)00129-1  1
2000 Medzhitov R, Janeway C. Innate immune recognition: mechanisms and pathways. Immunological Reviews. 173: 89-97. PMID 10719670 DOI: 10.1034/j.1600-065X.2000.917309.x  1
2000 Levine MH, Haberman AM, Sant'Angelo DB, Hannum LG, Cancro MP, Janeway CA, Shlomchik MJ. A B-cell receptor-specific selection step governs immature to mature B cell differentiation Proceedings of the National Academy of Sciences of the United States of America. 97: 2743-2748. PMID 10688906 DOI: 10.1073/pnas.050552997  1
2000 Abbas AK, Janeway CA. Immunology: Improving on nature in the twenty-first century Cell. 100: 129-138. PMID 10647937  1
1999 Viret C, Janeway CA. MHC and T cell development Reviews in Immunogenetics. 1: 91-104. PMID 11256575  1
1999 Medzhitov R, Janeway CA. Innate immune induction of the adaptive immune response. Cold Spring Harbor Symposia On Quantitative Biology. 64: 429-35. PMID 11232318  1
1999 Welte T, Leitenberg D, Dittel BN, al-Ramadi BK, Hansen WR, Xie B, Janeway CA, Bothwell AL, Bottomly K, Fu XY. The PTK-STAT signaling pathway has essential roles in T-cell activation in response to antigen stimulation. Cold Spring Harbor Symposia On Quantitative Biology. 64: 291-302. PMID 11232299  1
1999 Wong FS, Janeway CA. Insulin-dependent diabetes mellitus and its animal models Current Opinion in Immunology. 11: 643-647. PMID 10631549 DOI: 10.1016/S0952-7915(99)00031-X  1
1999 Janeway CA, Medzhitov R. Lipoproteins take their toll on the host. Current Biology : Cb. 9: R879-82. PMID 10607553  1
1999 Wong FS, Janeway CA. The role of CD4 vs. CD8 T cells in IDDM Journal of Autoimmunity. 13: 290-295. PMID 10550216 DOI: 10.1006/jaut.1999.0322  1
1999 Dittel BN, Štefanov́a I, Germain RN, Janeway CA. Cross-antagonism of a T cell clone expressing two distinct T cell receptors Immunity. 11: 289-298. PMID 10514007 DOI: 10.1016/S1074-7613(00)80104-1  1
1999 Buonfiglio D, Bragardo M, Bonissoni S, Redoglia V, Cauda R, Zupo S, Burgio VL, Wolff H, Franssila K, Gaidano G, Carbone A, Janeway CA, Dianzani U. Characterization of a novel human surface molecule selectively expressed by mature thymocytes, activated T cells and subsets of T cell lymphomas European Journal of Immunology. 29: 2863-2874. PMID 10508261  1
1999 Gobardhan D, Janeway CA. Development of CD8α/α and CD8α/β T cells in major histocompatibility complex class I-deficient mice Journal of Experimental Medicine. 190: 881-884. PMID 10499926 DOI: 10.1084/jem.190.6.881  1
1999 Janeway CA, Annicelli C, Appicelli J, Barlow A, Baron J, Carrithers M, Chen C, Chervonsky A, Cohen B, Dittel B, Evans T, Granata J, Hardardottir F, He X, Kaye J, et al. The role of self-recognition in receptor repertoire development Immunologic Research. 19: 107-118. PMID 10493166  1
1999 Blander JM, Visintin I, Janeway CA, Medzhitov R. Alpha(1,3)-fucosyltransferase VII and alpha(2,3)-sialyltransferase IV are up-regulated in activated CD4 T cells and maintained after their differentiation into Th1 and migration into inflammatory sites. Journal of Immunology (Baltimore, Md. : 1950). 163: 3746-52. PMID 10490970  1
1999 Wong FS, Karttunen J, Dumont C, Wen L, Visintin I, Pilip IM, Shastri N, Pamer EG, Janeway CA. Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library Nature Medicine. 5: 1026-1031. PMID 10470079 DOI: 10.1038/12465  1
1999 Kopp E, Medzhitov R, Carothers J, Xiao C, Douglas I, Janeway CA, Ghosh S. ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway. Genes & Development. 13: 2059-71. PMID 10465784  1
1999 Wong FS, Dittel BN, Janeway CA. Transgenes and knockout mutations in animal models of type 1 diabetes and multiple sclerosis Immunological Reviews. 169: 93-106. PMID 10450511 DOI: 10.1111/j.1600-065X.1999.tb01309.x  1
1999 Dittel BN, Visintin I, Merchant RM, Janeway CA. Presentation of the self antigen myelin basic protein by dendritic cells leads to experimental autoimmune encephalomyelitis Journal of Immunology. 163: 32-39. PMID 10384096  1
1999 Viret C, Wong FS, Janeway CA. Designing and maintaining the mature TCR repertoire: The continuum of self-peptide:self-MHC complex recognition Immunity. 10: 559-568. PMID 10367901 DOI: 10.1016/S1074-7613(00)80055-2  1
1999 Dittel BN, Merchant RM, Janeway CA. Evidence for Fas-dependent and Fas-independent mechanisms in the pathogenesis of experimental autoimmune encephalomyelitis Journal of Immunology. 162: 6392-6400. PMID 10352252  1
1999 Hoffmann JA, Kafatos FC, Janeway CA, Ezekowitz RA. Phylogenetic perspectives in innate immunity. Science (New York, N.Y.). 284: 1313-8. PMID 10334979 DOI: 10.1126/science.284.5418.1313  1
1999 Janeway CA. T-cell development: A role for self-peptides in positive selection Current Biology. 9: R342-R345. PMID 10322106 DOI: 10.1016/S0960-9822(99)80209-7  1
1999 Janeway CA. The discovery of T cell help for B cell antibody formation: A perspective from the 30th anniversary of this discovery Immunology and Cell Biology. 77: 177-179. PMID 10234554 DOI: 10.1046/j.1440-1711.1999.00814.x  1
1999 Welte T, Leitenberg D, Dittel BN, al-Ramadi BK, Xie B, Chin YE, Janeway CA, Bothwell AL, Bottomly K, Fu XY. STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation. Science (New York, N.Y.). 283: 222-5. PMID 9880255 DOI: 10.1126/science.283.5399.222  1
1999 Viret C, Barlow AK, Janeway CA. On the intrathymic intercellular transfer of self-determinants Immunology Today. 20: 8-10. DOI: 10.1016/S0167-5699(98)01372-3  1
1998 Wong FS, Visintin I, Shanabrough M, Leranth C, Janeway CA. A novel method for concurrent visualization of immunostain under light and electron microscopy in pancreatic islets Journal of Histochemistry and Cytochemistry. 46: 1341-1345. PMID 9815274  1
1998 Medzhitov R, Janeway CA. Innate immune recognition and control of adaptive immune responses. Seminars in Immunology. 10: 351-3. PMID 9799709 DOI: 10.1006/smim.1998.0136  1
1998 Janeway CA, Medzhitov R. Introduction: the role of innate immunity in the adaptive immune response Seminars in Immunology. 10: 349-50. PMID 9799708  1
1998 Medzhitov R, Preston-Hurlburt P, Kopp E, Stadlen A, Chen C, Ghosh S, Janeway CA. MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Molecular Cell. 2: 253-8. PMID 9734363  1
1998 Sant'Angelo DB, Lucas B, Waterbury PG, Cohen B, Brabb T, Goverman J, Germain RN, Janeway CA. A molecular map of T cell development. Immunity. 9: 179-86. PMID 9729038  1
1998 Chervonsky AV, Medzhitov RM, Denzin LK, Barlow AK, Rudensky AY, Janeway CA. Subtle conformational changes induced in major histocompatibility complex class II molecules by binding peptides. Proceedings of the National Academy of Sciences of the United States of America. 95: 10094-9. PMID 9707606 DOI: 10.1073/pnas.95.17.10094  1
1998 Janeway CA. Presidential address to The American Association of Immunologists: The road less traveled by: The role of innate immunity in the adaptive immune response Journal of Immunology. 161: 539-544. PMID 9670925  1
1998 Wong FS, Visintin I, Wen L, Granata J, Flavell R, Janeway CA. The role of lymphocyte subsets in accelerated diabetes in nonobese diabetic-rat insulin promoter-B7-1 (NOD-RIP-B7-1) mice Journal of Experimental Medicine. 187: 1985-1993. PMID 9625758 DOI: 10.1084/jem.187.12.1985  1
1998 Janeway CA. A tale of two T cells Immunity. 8: 391-394. PMID 9586629 DOI: 10.1016/S1074-7613(00)80544-0  1
1998 Barlow AK, He X, Janeway C. Exogenously provided peptides of a self-antigen can be processed into forms that are recognized by self-T cells Journal of Experimental Medicine. 187: 1403-1415. PMID 9565633 DOI: 10.1084/jem.187.9.1403  1
1998 Ståhls A, Hong SC, Liwszyc GE, Janeway C, Andersson LC, Wolff H. Signalling initiated with CD4-TCR or TCR-TCR interactions: Comparison of tyrosine phosphorylation patterns and CD45 effects Immunology Letters. 60: 103-109. PMID 9557951 DOI: 10.1016/S0165-2478(97)00136-3  1
1998 Medzhitov R, Janeway CA. An ancient system of host defense. Current Opinion in Immunology. 10: 12-5. PMID 9523104 DOI: 10.1016/S0952-7915(98)80024-1  1
1998 Medzhitov R, Janeway CA. Self-defense: the fruit fly style. Proceedings of the National Academy of Sciences of the United States of America. 95: 429-30. PMID 9435208  1
1998 Wong FS, Visintin I, Wen L, Granata J, Flavell RA, Janeway CA. CD4 and CD8 T cells are required for accelerated diabetes in NOD RIP-B7-1 transgenic mice Faseb Journal. 12: A1097.  1
1998 Dittel BN, Merchant RM, Janeway CA. Fas and FasL are involved in the pathogenesis of EAE Faseb Journal. 12: A1092.  1
1998 Janeway CA, Kupfer A, Viret C, Boursalian T, Goverman J, Bottomly K, Sant'Angelo D. T-cell development, survival, and signalling: A new concept of the role of self-peptide: Self-MHC complexes Immunologist. 6: 5-12.  1
1997 Dimarcq JL, Imler JL, Lanot R, Ezekowitz RA, Hoffmann JA, Janeway CA, Lagueux M. Treatment of l(2)mbn Drosophila tumorous blood cells with the steroid hormone ecdysone amplifies the inducibility of antimicrobial peptide gene expression. Insect Biochemistry and Molecular Biology. 27: 877-86. PMID 9474784 DOI: 10.1016/S0965-1748(97)00072-6  1
1997 Hong SC, Sant'Angelo DB, Dittel BN, Medzhitov R, Yoon ST, Waterbury PG, Janeway CA. The orientation of a T cell receptor to its MHC class II:peptide ligands. Journal of Immunology (Baltimore, Md. : 1950). 159: 4395-402. PMID 9379037  1
1997 Medzhitov R, Janeway CA. Innate immunity: the virtues of a nonclonal system of recognition. Cell. 91: 295-8. PMID 9363937 DOI: 10.1016/S0092-8674(00)80412-2  1
1997 Sant'Angelo DB, Waterbury PG, Cohen BE, Martin WD, Van Kaer L, Hayday AC, Janeway CA. The imprint of intrathymic self-peptides on the mature T cell receptor repertoire Immunity. 7: 517-524. PMID 9354472  1
1997 Wong FS, Janeway CA. The role of CD4 and CD8 T cells in type I diabetes in the NOD mouse Research in Immunology. 148: 327-332. PMID 9352597 DOI: 10.1016/S0923-2494(97)87242-2  1
1997 Medzhitov R, Preston-Hurlburt P, Janeway CA. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature. 388: 394-7. PMID 9237759 DOI: 10.1038/41131  1
1997 Dittel BN, Sant'Angelo DB, Janeway CA. Peptide Antagonists Inhibit Proliferation and the Production of IL-4 and/or IFN-γ in T Helper 1, T Helper 2, and T Helper 0 Clones Bearing the Same TCR Journal of Immunology. 158: 4065-4073. PMID 9126964  1
1997 Janeway CA, Chervonsky AV, Sant'Angelo D. T-cell receptors: Is the repertoire inherently MHC-specific? Current Biology. 7: R299-R300. PMID 9115392  1
1997 Chervonsky AV, Wang Y, Wong FS, Visintin I, Flavell RA, Janeway CA, Matis LA. The role of Fas in autoimmune diabetes Cell. 89: 17-24. PMID 9094710  1
1997 Medzhitov R, Janeway CA. Innate immunity: impact on the adaptive immune response. Current Opinion in Immunology. 9: 4-9. PMID 9039775 DOI: 10.1016/S0952-7915(97)80152-5  1
1997 Romanic AM, Graesser D, Baron JL, Visintin I, Janeway CA, Madri JA. T cell adhesion to endothelial cells and extracellular matrix is modulated upon transendothelial cell migration. Laboratory Investigation; a Journal of Technical Methods and Pathology. 76: 11-23. PMID 9010446  1
1996 Wolf SD, Dittel BN, Hardardottir F, Janeway CA. Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice Journal of Experimental Medicine. 184: 2271-2278. PMID 8976182 DOI: 10.1084/jem.184.6.2271  1
1996 Redoglia V, Dianzani U, Rojo JM, Portolés P, Bragardo M, Wolff H, Buonfiglio D, Bonissoni S, Janeway CA. Characterization of H4: A mouse T lymphocyte activation molecule functionally associated with the CD3/T cell receptor European Journal of Immunology. 26: 2781-2789. PMID 8921969 DOI: 10.1002/eji.1830261134  1
1996 Grewal IS, Grewal KD, Wong FS, Picarella DE, Janeway CA, Flavell RA. Local expression of transgene encoded TNFα in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells Journal of Experimental Medicine. 184: 1963-1974. PMID 8920883  1
1996 Janeway CA, Bottomly K. Responses of T cells to ligands for the T-cell receptor Seminars in Immunology. 8: 109-115. PMID 8920245 DOI: 10.1006/smim.1996.0013  1
1996 McInerney MF, Flynn JC, Goldblatt PJ, Najjar SM, Sherwin RS, Janeway CA. High density insulin receptor-positive T lymphocytes from nonobese diabetic mice transfer insulitis and diabetes. Journal of Immunology (Baltimore, Md. : 1950). 157: 3716-26. PMID 8871675  1
1996 Medzhitov R, Janeway CA. On the semantics of immune recognition. Research in Immunology. 147: 208-14. PMID 8844897 DOI: 10.1016/0923-2494(96)87222-1  1
1996 Janeway CA, Goodnow CC, Medzhitov R. Danger - pathogen on the premises! Immunological tolerance. Current Biology : Cb. 6: 519-22. PMID 8805259  1
1996 Grewal IS, Foellmer HG, Grewal KD, Xu J, Hardardottir F, Baron JL, Janeway CA, Flavell RA. Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis Science. 273: 1864-1867. PMID 8791592  1
1996 Hong SC, Waterbury G, Janeway CA. Different superantigens interact with distinct sites in the Vβ domain of a single T cell receptor Journal of Experimental Medicine. 183: 1437-1446. PMID 8666902 DOI: 10.1084/jem.183.4.1437  1
1996 Sant'Angelo DB, Waterbury G, Preston-Hurlburt P, Yoon ST, Medzhitov R, Hong SC, Janeway CA. The specificity and orientation of a TCR to its peptide-MHC class II ligands. Immunity. 4: 367-76. PMID 8612131 DOI: 10.1016/S1074-7613(00)80250-2  1
1996 Chen Y, Inobe JI, Kuchroo VK, Baron JL, Janeway CA, Weiner HL. Oral tolerance in myelin basic protein T-cell receptor transgenic mice: Suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells Proceedings of the National Academy of Sciences of the United States of America. 93: 388-391. PMID 8552644 DOI: 10.1073/pnas.93.1.388  1
1996 Wong FS, Visintin I, Wen L, Flavell RA, Janeway CA. CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells Journal of Experimental Medicine. 183: 67-76. PMID 8551245 DOI: 10.1084/jem.183.1.67  1
1996 McInerney MF, Guan L, Flynn JC, Oravecz KI, Burkey J, Janeway CA. Defining autoantigen recognition by islet-specific CD8+ t cell hybridomas from nonobese diabetic (NOD) mice Faseb Journal. 10: A1312.  1
1995 Janeway CA. Ligands for the T-cell receptor: hard times for avidity models Immunology Today. 16: 223-225. PMID 7779252 DOI: 10.1016/0167-5699(95)80163-4  1
1995 Campos-Neto A, Soong L, Cordova JL, Sant'Angelo D, Skeiky YAW, Ruddle NH, Reed SG, Janeway C, McMahon-Pratt D. Cloning and expression of a Leishmania donovani gene instructed by a peptide isolated from major histocompatibility complex class II molecules of infected macrophages Journal of Experimental Medicine. 182: 1423-1433. PMID 7595213 DOI: 10.1084/jem.182.5.1423  1
1995 Chervonsky AV, Golovkina TV, Ross SR, Janeway CA. Differences in the avidity of TCR interactions with a superantigenic ligand affect negative selection but do not allow positive selection Journal of Immunology. 155: 5115-5123. PMID 7594520  1
1995 Wu Y, Guo Y, Janeway CA, Liu Y. Signaling by a new anti-Thy 1 monoclonal antibody inhibits T cell proliferation and interferes with T-cell-mediated induction of costimulatory molecule B7-2 Cellular Immunology. 165: 266-277. PMID 7553891 DOI: 10.1006/cimm.1995.1213  1
1995 Chervonsky AV, Xu J, Barlow AK, Khery M, Flavell RA, Janeway CA. Direct physical interaction involving CD40 ligand on T cells and CD40 on B cells is required to propagate MMTV Immunity. 3: 139-146. PMID 7542547 DOI: 10.1016/1074-7613(95)90166-3  1
1995 Wong S, Guerder S, Visintin I, Reich EP, Swenson KE, Flavell RA, Janeway CA. Expression of the co-stimulator molecule B7-1 in pancreatic β-cells accelerates diabetes in the NOD mouse Diabetes. 44: 326-329. PMID 7533734  1
1995 Hardardottir F, Baron JL, Janeway CA. T cells with two functional antigen-specific receptors Proceedings of the National Academy of Sciences of the United States of America. 92: 354-358. PMID 7530361 DOI: 10.1073/pnas.92.2.354  1
1995 Chang CH, Hong SC, Hughes CC, Janeway CA, Flavell RA. CIITA activates the expression of MHC class II genes in mouse T cells. International Immunology. 7: 1515-8. PMID 7495759 DOI: 10.1093/intimm/7.9.1515  1
1995 Janeway CA, Medhzhitov R, Pfeiffer C, Tao Xiang, Bottomly K. Altered peptide ligands. Conformational changes in the TcR Immunologist. 3: 41-44.  1
1994 Golovkina TV, Chervonsky A, Prescott JA, Janeway CA, Ross SR. The mouse mammary tumor virus envelope gene product is required for superantigen presentation to T cells Journal of Experimental Medicine. 179: 439-446. PMID 8294859  1
1994 Yagi J, Nakata M, Uchiyama T, Nishikawa M, Mizushima Y, Nishioka K, Ito K, Yagita H, Okumura K, Janeway CA, Yamamoto K. Superantigen-like properties of an antibody bispecific for MHC class II molecules and the Vβ domain of the T cell antigen receptor Journal of Immunology. 152: 3833-3841. PMID 8144952  1
1994 Reich EP, Von Grafenstein H, Barlow A, Swenson KE, Williams K, Janeway CA. Self peptides isolated from MHC glycoproteins of non-obese diabetic mice Journal of Immunology. 152: 2279-2288. PMID 8133041  1
1994 Wolff H, Janeway C. Anti-CD45 augments response of a T(h)2 clone to TCR cross-linking Scandinavian Journal of Immunology. 40: 22-25. PMID 8029640 DOI: 10.1111/j.1365-3083.1994.tb03428.x  1
1994 Yagi J, Uchiyama T, Janeway CA. Stimulator cell type influences the response of T cells to staphylococcal enterotoxins Journal of Immunology. 152: 1154-1162. PMID 7905498  1
1994 Janeway CA, Bottomly K. Signals and signs for lymphocyte responses Cell. 76: 275-285. PMID 7904901 DOI: 10.1016/0092-8674(94)90335-2  1
1994 Janeway CA. Thymic selection: Two pathways to life and two to death Immunity. 1: 3-6. PMID 7889396  1
1994 Yoon ST, Dianzani U, Bottomly K, Janeway CA. Both high and low avidity antibodies to the T cell receptor can have agonist or antagonist activity Immunity. 1: 563-569. PMID 7600285  1
1994 Kennedy MK, Mohler KM, Shanebeck KD, Baum PR, Picha KS, Otten-Evans CA, Janeway CA, Grabstein KH. Induction of B cell costimulatory function by recombinant murine CD40 ligand European Journal of Immunology. 24: 116-123. PMID 7517359 DOI: 10.1002/eji.1830240118  1
1994 Baron JL, Reich EP, Visintin I, Janeway CA. The pathogenesis of adoptive murine autoimmune diabetes requires an interaction between α4-integrins and vascular cell adhesion molecule-1 Journal of Clinical Investigation. 93: 1700-1708. PMID 7512990  1
1993 Janeway CA. Are there cellular superantigens? Immunological Reviews. 189-200. PMID 8486392  1
1993 Shepherd JC, Schumacher TN, Ashton-Rickardt PG, Imaeda S, Ploegh HL, Janeway CA, Tonegawa S. TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective. Cell. 74: 577-84. PMID 8348620 DOI: 10.1016/0092-8674(93)80058-M  1
1993 Janeway CA, Golstein P. Lymphocyte activation and effector functions. The role of cell surface molecules Current Opinion in Immunology. 5: 313-323. PMID 8347294 DOI: 10.1016/0952-7915(93)90048-W  1
1993 Wolff CHJ, Hong SC, Von Grafenstein H, Janeway CA. TCR-CD4 and TCR-TCR interactions as distinctive mechanisms for the induction of increased intracellular calcium in T-cell signalling Journal of Immunology. 151: 1337-1345. PMID 8335930  1
1993 Janeway CA, Mamula MJ, Rudensky AY. Rules for peptide presentation by MHC class II molecules International Reviews of Immunology. 10: 301-311. PMID 8294843 DOI: 10.3109/08830189309061705  1
1993 Sano Y, Dudley E, Carding S, Lin RH, Hayday AC, Janeway CA. γδ T-cell lines isolated from intestinal epithelium respond to a B-cell lymphoma Immunology. 80: 388-394. PMID 8288315  1
1993 Rudensky A, Janeway CA. Studies on naturally processed peptides associated with MHC class II molecules Chemical Immunology. 57: 134-151. PMID 8260086  1
1993 Eisen HN, Tsomides T, Udaka K, Walden P, Fukusen N. Incorrect attribution of peptide source. Cell. 75: 613. PMID 8242737 DOI: 10.1016/0092-8674(93)90482-6  1
1993 Janeway CA. How the immune system recognizes invaders Scientific American. 269: 73-79. PMID 8211093  1
1993 Mamula MJ, Janeway CA. Do B cells drive the diversification of immune responses? Immunology Today. 14: 151-152. PMID 8098941  1
1993 Baron JL, Madri JA, Ruddle NH, Hashim G, Janeway CA. Surface expression of α4 integrin by CD4 T cells is required for their entry into brain parenchyma Journal of Experimental Medicine. 177: 57-68. PMID 7678116 DOI: 10.1084/jem.177.1.57  1
1993 Janeway CA, Reich EP, Graffenstein HV, Barlow A, Flavell RA, Sherwin R. Summary of talk in orlando protection against insulin-dependent diabetes mellitus Autoimmunity. 15: 4-5. DOI: 10.3109/08916939309008849  1
1993 Janeway CA. Chance or necessity? Current Biology. 3: 282-284. DOI: 10.1016/0960-9822(93)90179-R  1
1993 Janeway C, Mamula M. B cells drive diversification - But not directly: And a reply from Charlie Janeway and Mark Mamula Immunology Today. 14: 154. DOI: 10.1016/0167-5699(93)90276-Q  1
1992 Janeway CA. The immune system evolved to discriminate infectious nonself from noninfectious self Immunology Today. 13: 11-16. PMID 1739426 DOI: 10.1016/0167-5699(92)90198-G  1
1992 Van Noort JM, Janeway CA, Rudensky AY, Preston-Hurlburt P. Peptides bound to MHC [11] Nature. 357: 120. PMID 1579161  1
1992 Janeway CA. The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation Annual Review of Immunology. 10: 645-674. PMID 1534242  1
1992 Dianzani U, Redoglia V, Malavasi F, Bragardo M, Pileri A, Janeway CA, Bottomly K. Isoform-specific associations of CD45 with accessory molecules in human T lymphocytes European Journal of Immunology. 22: 365-371. PMID 1531636  1
1992 Dianzani U, Shaw A, Fernandez-Cabezudo M, Janeway CA. Extensive cd4 cross-linking inhibits t cell activation by anti-receptor antibody but not by antigen International Immunology. 4: 995-1001. PMID 1390442 DOI: 10.1093/intimm/4.9.995  1
1992 Liu Y, Jones B, Brady W, Janeway CA, Linley PS. Co-stimulation of murine CD4 T cell growth: Cooperation between B7 and heat-stable antigen European Journal of Immunology. 22: 2855-2859. PMID 1385153  1
1992 Rath S, Lin RH, Rudensky A, Janeway CA. T and B cell receptors discriminate major histocompatibility complex class II conformations influenced by the invariant chain European Journal of Immunology. 22: 2121-2127. PMID 1379187  1
1992 Murphy DB, Rath S, Pizzo E, Rudensky AY, George A, Larson JK, Janeway CA. Monoclonal antibody detection of a major self peptide MHC class II complex Journal of Immunology. 148: 3483-3491. PMID 1375245  1
1992 Dianzani U, Shaw A, Al-Ramadi BK, Kubo RT, Janeway CA. Physical association of CD4 with the T cell receptor Journal of Immunology. 148: 678-688. PMID 1370513  1
1992 Wolff H, Novak T, Shaw A, Dianzani U, Janeway CA. High levels of IL-2 alter signal transduction in cloned IL-4-producing CD4 T cells Journal of Immunology. 149: 2996-3002. PMID 1357032  1
1992 Liu Y, Janeway CA. Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells Proceedings of the National Academy of Sciences of the United States of America. 89: 3845-3849. PMID 1349172  1
1992 Liu Y, Jones B, Aruffo A, Sullivan KM, Linsley PS, Janeway CA. Heat-stable antigen is a costimulatory molecule for CD4 T cell growth Journal of Experimental Medicine. 175: 437-445. PMID 1346270  1
1992 Rudensky AY, Preston-Hurlburt P, Al-Ramadi BK, Rothbard J, Janeway CA. Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs Nature. 359: 429-431. PMID 1328884  1
1992 Mamula MJ, Lin RH, Janeway CA, Hardin JA. Breaking T cell tolerance with foreign and self co-immunogens: A study of autoimmune B and T cell epitopes of cytochrome c Journal of Immunology. 149: 789-795. PMID 1321851  1
1992 Hong SC, Chelouche A, Lin RH, Shaywitz D, Braunstein NS, Glimcher L, Janeway CA. An MHC interaction site maps to the amino-terminal half of the T cell receptor alpha chain variable domain. Cell. 69: 999-1009. PMID 1318787 DOI: 10.1016/0092-8674(92)90618-M  1
1992 Janeway C, Rudensky A, Rath S, Murphy D. It is easier for a camel to pass the needle's eye Current Biology. 2: 26-28. DOI: 10.1016/0960-9822(92)90419-B  1
1992 Janeway CA. High fives or hand clasps? Current Biology. 2: 591-593. DOI: 10.1016/0960-9822(92)90163-5  1
1992 Janeway CA. The case of the missing CD4s Current Biology. 2: 359-361. DOI: 10.1016/0960-9822(92)90061-E  1
1991 Janeway CA, Rath S, Yagi J. Vβ selective elements: Self and non-self Behring Institut Mitteilungen. 177-182. PMID 2049036  1
1991 Janeway C. Synthetic vaccines. Peptides of fortune Nature. 353: 792. PMID 1944552 DOI: 10.1038/353792a0  1
1991 Yagi J, Rath S, Janeway CA. Control of T cell responses to staphylococcal enterotoxins by stimulator cell MHC class II polymorphism Journal of Immunology. 147: 1398-1405. PMID 1907996  1
1991 Janeway C. MIs: Makes a little sense Nature. 349: 459-461. PMID 1899473  1
1991 Lin RH, Mamula MJ, Hardin JA, Janeway CA. Induction of autoreactive B cells allows priming of autoreactive T cells Journal of Experimental Medicine. 173: 1433-1439. PMID 1851798  1
1991 Janeway CA. Selective elements for the Vβ region of the T cell receptor: MIs and the bacterial toxic mitogens Advances in Immunology. 50: 1-53. PMID 1835267  1
1991 Tonegawa S, Berns A, Bonneville M, Farr AG, Ishida I, Ito K, Itohara S, Janeway CA, Kanagawa O, Kubo R. Diversity, development, ligands, and probable functions of gamma delta T cells. Advances in Experimental Medicine and Biology. 292: 53-61. PMID 1835263  1
1991 Liu Y, Janeway CA. Monoclonal antibodies against T cell receptor/CD3 complex induce cell death of Th1 clones in the absence of accessory cells Advances in Experimental Medicine and Biology. 292: 105-114. PMID 1835259  1
1991 Mann R, Dudley E, Sano Y, O'Brien R, Born W, Janeway C, Hayday A. Modulation of murine self antigens by mycobacterial components Current Topics in Microbiology and Immunology. 173: 151-157. PMID 1833135  1
1991 Liu Y, Janeway CA. Microbial induction of co-stimulatory activity for CD4 T-cell growth International Immunology. 3: 323-332. PMID 1831651 DOI: 10.1093/intimm/3.4.323  1
1991 McInerney MF, Rath S, Janeway CA. Exclusive expression of MHC class II proteins on CD45+ cells in pancreatic islets of NOD mice Diabetes. 40: 648-651. PMID 1827081  1
1991 Ptak W, Janeway CA, Marcinkiewicz J, Flood PM. Regulatory responses in contact sensitivity: Afferent suppressor T cells inhibit the activation of efferent suppressor T cells Cellular Immunology. 132: 400-410. PMID 1824829 DOI: 10.1016/0008-8749(91)90037-C  1
1991 Nakagawa TY, Von Grafenstein H, Sears JE, Williams J, Janeway CA, Flavell RA. The use of the polymerase chain reaction to map CD4+ T cell epitopes European Journal of Immunology. 21: 2851-2855. PMID 1718762  1
1991 Janeway CA. The co-receptor function of CD4 Seminars in Immunology. 3: 153-160. PMID 1716173  1
1991 Rudensky AY, Rath S, Preston-Hurlburt P, Murphy DB, Janeway CA. On the complexity of self Nature. 353: 660-662. PMID 1656278  1
1991 Janeway CA. To thine own self be true .. Current Biology. 1: 239-241. DOI: 10.1016/0960-9822(91)90069-9  1
1991 Janeway C. Peptides of fortune Nature. 353: 792.  1
1990 Portolés P, Rojo JM, Janeway CA. A simple method for the radioactive iodination of CD4 molecules Journal of Immunological Methods. 129: 105-109. PMID 2338494 DOI: 10.1016/0022-1759(90)90426-V  1
1990 Janeway CA. Self superantigens? Cell. 63: 659-661. PMID 2225070 DOI: 10.1016/0092-8674(90)90130-7  1
1990 Janeway CA. Research on the frontlines of defence Research in Immunology. 141: 688-695. PMID 2151357 DOI: 10.1016/0923-2494(90)90094-F  1
1990 Yagi J, Janeway CA. Ligand thresholds at different stages of T cell development International Immunology. 2: 83-89. PMID 2150922 DOI: 10.1093/intimm/2.1.83  1
1990 Liu Y, Janeway CA. Interferon γ plays a critical role in induced cell death of effector T cell: A possible third mechanism of self-tolerance Journal of Experimental Medicine. 172: 1735-1739. PMID 2147950 DOI: 10.1084/jem.172.6.1735  1
1990 Ptak W, Flood P, Janeway CA. Antibody-activated immunoregulatory T cells are defective in B cell deprived mice Journal of Molecular and Cellular Immunology. 4: 281-290. PMID 2144969  1
1990 Yagi J, Baron J, Buxser S, Janeway CA. Bacterial proteins that mediate the association of a defined subset of T cell receptor:CD4 complexes with class II MHC Journal of Immunology. 144: 892-901. PMID 2136903  1
1990 Bonneville M, Itohara S, Krecko EG, Mombaerts P, Ishida I, Katsuki M, Berns A, Farr AG, Janeway CA, Tonegawa S. Transgenic mice demonstrate that epithelial homing of gamma/delta T cells is determined by cell lineages independent of T cell receptor specificity. The Journal of Experimental Medicine. 171: 1015-26. PMID 2109035  1
1990 Dianzani U, Luqman M, Rojo J, Yagi J, Baron JL, Woods A, Janeway CA, Bottemly K. Molecular associations on the T cell surface correlate with immunological memory European Journal of Immunology. 20: 2249-2257. PMID 1978709  1
1990 Janeway CA. JMCI: The last issue Journal of Molecular and Cellular Immunology. 4: 293.  1
1990 Janeway CA, Rojo J, Portoles P, Dunn E, Bottomly K. Idiotypic interactions between B- and T-lymphocyte receptors Idiotype Networks in Biology and Medicine: Proceedings of the Congress On Idiotype Networks in Biology and Medicine. Ics862. 125-131.  1
1989 Janeway CA. A primitive immune system Nature. 341: 108.  1
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