| Year |
Citation |
Score |
| 2018 |
Dyer A, Schoeps B, Frost S, Jakeman PG, Scott EM, Freedman J, Seymour LW. Antagonism of glycolysis and reductive carboxylation of glutamine potentiates activity of oncolytic adenoviruses in cancer cells. Cancer Research. PMID 30487139 DOI: 10.1158/0008-5472.Can-18-1326 |
0.32 |
|
| 2018 |
Freedman JD, Duffy MR, Lei-Rossmann J, Muntzer A, Scott EM, Hagel J, Campo L, Bryant RJ, Verrill C, Lambert A, Miller P, Champion BR, Seymour LW, Fisher KD. An Oncolytic Virus Expressing a T-cell Engager Simultaneously Targets Cancer and Immunosuppressive Stromal Cells. Cancer Research. PMID 30449733 DOI: 10.1158/0008-5472.Can-18-1750 |
0.333 |
|
| 2017 |
Scott EM, Duffy MR, Freedman JD, Fisher KD, Seymour LW. Solid Tumor Immunotherapy with T Cell Engager-Armed Oncolytic Viruses. Macromolecular Bioscience. PMID 28902983 DOI: 10.1002/Mabi.201700187 |
0.322 |
|
| 2017 |
O'Cathail SM, Pokrovska TD, Maughan TS, Fisher KD, Seymour LW, Hawkins MA. Combining Oncolytic Adenovirus with Radiation-A Paradigm for the Future of Radiosensitization. Frontiers in Oncology. 7: 153. PMID 28791251 DOI: 10.3389/Fonc.2017.00153 |
0.341 |
|
| 2017 |
Freedman JD, Hagel J, Scott EM, Psallidas I, Gupta A, Spiers L, Miller P, Kanellakis N, Ashfield R, Fisher KD, Duffy MR, Seymour LW. Oncolytic adenovirus expressing bispecific antibody targets T-cell cytotoxicity in cancer biopsies. Embo Molecular Medicine. PMID 28634161 DOI: 10.15252/Emmm.201707567 |
0.325 |
|
| 2017 |
Dyer A, Di Y, Calderon H, Illingworth S, Kueberuwa G, Tedcastle A, Jakeman P, Chia SL, Brown A, Silva MA, Barlow D, Beadle J, Hermiston T, Ferguson DJ, Champion B, ... ... Seymour LW, et al. Oncolytic Group B Adenovirus Enadenotucirev Mediates Non-apoptotic Cell Death with Membrane Disruption and Release of Inflammatory Mediators. Molecular Therapy Oncolytics. 4: 18-30. PMID 28345021 DOI: 10.1016/J.Omto.2016.11.003 |
0.31 |
|
| 2017 |
Chia SL, Lei J, Ferguson DJ, Dyer A, Fisher KD, Seymour LW. Group B adenovirus enadenotucirev infects polarised colorectal cancer cells efficiently from the basolateral surface expected to be encountered during intravenous delivery to treat disseminated cancer. Virology. 505: 162-171. PMID 28260622 DOI: 10.1016/J.Virol.2017.02.011 |
0.305 |
|
| 2016 |
Seymour LW, Fisher KD. Oncolytic viruses: finally delivering. British Journal of Cancer. PMID 26766734 DOI: 10.1038/Bjc.2015.481 |
0.338 |
|
| 2015 |
Tedcastle A, Illingworth S, Brown A, Seymour LW, Fisher KD. Actin resistant DNAse I expression from oncolytic adenovirus Enadenotucirev enhances its intratumoural spread and reduces tumour growth. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26708004 DOI: 10.1038/Mt.2015.233 |
0.321 |
|
| 2015 |
Lynn GM, Laga R, Darrah PA, Ishizuka AS, Balaci AJ, Dulcey AE, Pechar M, Pola R, Gerner MY, Yamamoto A, Buechler CR, Quinn KM, Smelkinson MG, Vanek O, Cawood R, ... ... Seymour LW, et al. In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity. Nature Biotechnology. 33: 1201-10. PMID 26501954 DOI: 10.1038/Nbt.3371 |
0.305 |
|
| 2015 |
Kostka L, Šubr V, Laga R, Chytil P, Ulbrich K, Seymour LW, Etrych T. Nanotherapeutics shielded with a pH responsive polymeric layer. Physiological Research / Academia Scientiarum Bohemoslovaca. 64: S29-40. PMID 26447593 DOI: 10.33549/Physiolres.933139 |
0.382 |
|
| 2015 |
Mo S, Carlisle R, Laga R, Myers R, Graham S, Cawood R, Ulbrich K, Seymour L, Coussios CC. Increasing the density of nanomedicines improves their ultrasound-mediated delivery to tumours. Journal of Controlled Release : Official Journal of the Controlled Release Society. 210: 10-8. PMID 25975831 DOI: 10.1016/J.Jconrel.2015.05.265 |
0.34 |
|
| 2015 |
Jakeman PG, Hills TE, Tedcastle AB, Di Y, Fisher KD, Seymour LW. Improved in vitro human tumor models for cancer gene therapy. Human Gene Therapy. 26: 249-56. PMID 25808057 DOI: 10.1089/Hum.2015.028 |
0.312 |
|
| 2014 |
Di Y, Seymour L, Fisher K. Activity of a group B oncolytic adenovirus (ColoAd1) in whole human blood. Gene Therapy. 21: 440-3. PMID 24553347 DOI: 10.1038/Gt.2014.2 |
0.321 |
|
| 2013 |
Bazan-Peregrino M, Sainson RC, Carlisle RC, Thoma C, Waters RA, Arvanitis C, Harris AL, Hernandez-Alcoceba R, Seymour LW. Combining virotherapy and angiotherapy for the treatment of breast cancer. Cancer Gene Therapy. 20: 461-8. PMID 23846253 DOI: 10.1038/Cgt.2013.41 |
0.302 |
|
| 2008 |
Bazan-Peregrino M, Carlisle RC, Purdie L, Seymour LW. Factors influencing retention of adenovirus within tumours following direct intratumoural injection. Gene Therapy. 15: 688-94. PMID 18288207 DOI: 10.1038/Gt.2008.2 |
0.303 |
|
| 2008 |
Morrison J, Briggs SS, Green N, Fisher K, Subr V, Ulbrich K, Kehoe S, Seymour LW. Virotherapy of ovarian cancer with polymer-cloaked adenovirus retargeted to the epidermal growth factor receptor. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 244-51. PMID 18071336 DOI: 10.1038/Sj.Mt.6300363 |
0.365 |
|
| 2007 |
Stevenson M, Hale AB, Hale SJ, Green NK, Black G, Fisher KD, Ulbrich K, Fabra A, Seymour LW. Incorporation of a laminin-derived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via alpha6-integrins. Cancer Gene Therapy. 14: 335-45. PMID 17235355 DOI: 10.1038/Sj.Cgt.7701022 |
0.391 |
|
| 2007 |
Bazan-Peregrino M, Seymour LW, Harris AL. Gene therapy targeting to tumor endothelium. Cancer Gene Therapy. 14: 117-27. PMID 17096029 DOI: 10.1038/Sj.Cgt.7701001 |
0.33 |
|
| 2005 |
Parker AL, Fisher KD, Oupicky D, Read ML, Nicklin SA, Baker AH, Seymour LW. Enhanced gene transfer activity of peptide-targeted gene-delivery vectors. Journal of Drug Targeting. 13: 39-51. PMID 15848953 DOI: 10.1080/10611860400020449 |
0.302 |
|
| 2004 |
Howard KA, Li XW, Somavarapu S, Singh J, Green N, Atuah KN, Ozsoy Y, Seymour LW, Alpar HO. Formulation of a microparticle carrier for oral polyplex-based DNA vaccines. Biochimica Et Biophysica Acta. 1674: 149-57. PMID 15374619 DOI: 10.1016/J.Bbagen.2004.06.009 |
0.382 |
|
| 2004 |
Barrett LB, Berry M, Ying WB, Hodgkin MN, Seymour LW, Gonzalez AM, Read ML, Baird A, Logan A. CTb targeted non-viral cDNA delivery enhances transgene expression in neurons. The Journal of Gene Medicine. 6: 429-38. PMID 15079817 DOI: 10.1002/Jgm.524 |
0.342 |
|
| 2003 |
Read ML, Bremner KH, Oupický D, Green NK, Searle PF, Seymour LW. Vectors based on reducible polycations facilitate intracellular release of nucleic acids. The Journal of Gene Medicine. 5: 232-45. PMID 12666189 DOI: 10.1002/Jgm.331 |
0.323 |
|
| 2002 |
Ward CM, Pechar M, Oupicky D, Ulbrich K, Seymour LW. Modification of pLL/DNA complexes with a multivalent hydrophilic polymer permits folate-mediated targeting in vitro and prolonged plasma circulation in vivo. The Journal of Gene Medicine. 4: 536-47. PMID 12221647 DOI: 10.1002/Jgm.296 |
0.409 |
|
| 2002 |
Oupický D, Ogris M, Seymour LW. Development of long-circulating polyelectrolyte complexes for systemic delivery of genes. Journal of Drug Targeting. 10: 93-8. PMID 12074545 DOI: 10.1080/10611860290016685 |
0.399 |
|
| 2002 |
Maruta F, Parker AL, Fisher KD, Hallissey MT, Ismail T, Rowlands DC, Chandler LA, Kerr DJ, Seymour LW. Identification of FGF receptor-binding peptides for cancer gene therapy. Cancer Gene Therapy. 9: 543-52. PMID 12032665 DOI: 10.1038/Sj.Cgt.7700470 |
0.328 |
|
| 2002 |
Reschel T, Konák C, Oupický D, Seymour LW, Ulbrich K. Physical properties and in vitro transfection efficiency of gene delivery vectors based on complexes of DNA with synthetic polycations. Journal of Controlled Release : Official Journal of the Controlled Release Society. 81: 201-17. PMID 11992692 DOI: 10.1016/S0168-3659(02)00045-7 |
0.365 |
|
| 2002 |
Oupicky D, Ogris M, Howard KA, Dash PR, Ulbrich K, Seymour LW. Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 463-72. PMID 11945074 DOI: 10.1006/Mthe.2002.0568 |
0.371 |
|
| 2002 |
Seymour LW, Ferry DR, Anderson D, Hesslewood S, Julyan PJ, Poyner R, Doran J, Young AM, Burtles S, Kerr DJ. Hepatic drug targeting: phase I evaluation of polymer-bound doxorubicin. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 20: 1668-76. PMID 11896118 DOI: 10.1200/Jco.20.6.1668 |
0.362 |
|
| 2002 |
Parker AL, Oupicky D, Dash PR, Seymour LW. Methodologies for monitoring nanoparticle formation by self-assembly of DNA with poly(l-lysine). Analytical Biochemistry. 302: 75-80. PMID 11846378 DOI: 10.1006/Abio.2001.5507 |
0.336 |
|
| 2002 |
Oupický D, Parker AL, Seymour LW. Laterally stabilized complexes of DNA with linear reducible polycations: strategy for triggered intracellular activation of DNA delivery vectors. Journal of the American Chemical Society. 124: 8-9. PMID 11772047 DOI: 10.1021/Ja016440N |
0.401 |
|
| 2001 |
Carlisle RC, Bettinger T, Ogris M, Hale S, Mautner V, Seymour LW. Adenovirus hexon protein enhances nuclear delivery and increases transgene expression of polyethylenimine/plasmid DNA vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 4: 473-83. PMID 11708884 DOI: 10.1006/Mthe.2001.0472 |
0.349 |
|
| 2001 |
Ogris M, Carlisle RC, Bettinger T, Seymour LW. Melittin enables efficient vesicular escape and enhanced nuclear access of nonviral gene delivery vectors. The Journal of Biological Chemistry. 276: 47550-5. PMID 11600500 DOI: 10.1074/Jbc.M108331200 |
0.387 |
|
| 2001 |
Bettinger T, Carlisle RC, Read ML, Ogris M, Seymour LW. Peptide-mediated RNA delivery: a novel approach for enhanced transfection of primary and post-mitotic cells. Nucleic Acids Research. 29: 3882-91. PMID 11557821 DOI: 10.1093/Nar/29.18.3882 |
0.318 |
|
| 2001 |
Oupický D, Carlisle RC, Seymour LW. Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo. Gene Therapy. 8: 713-24. PMID 11406766 DOI: 10.1038/Sj.Gt.3301446 |
0.388 |
|
| 2001 |
Atkinson SF, Bettinger T, Seymour LW, Behr JP, Ward CM. Conjugation of folate via gelonin carbohydrate residues retains ribosomal-inactivating properties of the toxin and permits targeting to folate receptor positive cells. The Journal of Biological Chemistry. 276: 27930-5. PMID 11359781 DOI: 10.1074/Jbc.M102825200 |
0.345 |
|
| 2001 |
Fisher KD, Stallwood Y, Green NK, Ulbrich K, Mautner V, Seymour LW. Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies. Gene Therapy. 8: 341-8. PMID 11313809 DOI: 10.1038/Sj.Gt.3301389 |
0.392 |
|
| 2001 |
Ward CM, Read ML, Seymour LW. Systemic circulation of poly(L-lysine)/DNA vectors is influenced by polycation molecular weight and type of DNA: differential circulation in mice and rats and the implications for human gene therapy. Blood. 97: 2221-9. PMID 11290582 DOI: 10.1182/Blood.V97.8.2221 |
0.367 |
|
| 2000 |
Fisher KD, Ulbrich K, Subr V, Ward CM, Mautner V, Blakey D, Seymour LW. A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression. Gene Therapy. 7: 1337-43. PMID 10918506 DOI: 10.1038/Sj.Gt.3301230 |
0.421 |
|
| 2000 |
Howard KA, Dash PR, Read ML, Ward K, Tomkins LM, Nazarova O, Ulbrich K, Seymour LW. Influence of hydrophilicity of cationic polymers on the biophysical properties of polyelectrolyte complexes formed by self-assembly with DNA. Biochimica Et Biophysica Acta. 1475: 245-55. PMID 10913823 DOI: 10.1016/S0304-4165(00)00076-3 |
0.389 |
|
| 2000 |
Ward CM, Acheson N, Seymour LW. Folic acid targeting of protein conjugates into ascites tumour cells from ovarian cancer patients. Journal of Drug Targeting. 8: 119-23. PMID 10852343 DOI: 10.3109/10611860008996857 |
0.336 |
|
| 2000 |
Read ML, Dash PR, Clark A, Howard KA, Oupicky D, Toncheva V, Alpar HO, Schacht EH, Ulbrich K, Seymour LW. Physicochemical and biological characterisation of an antisense oligonucleotide targeted against the bcl-2 mRNA complexed with cationic-hydrophilic copolymers. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 10: 169-77. PMID 10767594 DOI: 10.1016/S0928-0987(00)00069-5 |
0.398 |
|
| 2000 |
Dekie L, Toncheva V, Dubruel P, Schacht EH, Barrett L, Seymour LW. Poly-L-glutamic acid derivatives as vectors for gene therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 65: 187-202. PMID 10699280 DOI: 10.1016/S0168-3659(99)00235-7 |
0.386 |
|
| 2000 |
Oupický D, Konák C, Ulbrich K, Wolfert MA, Seymour LW. DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers. Journal of Controlled Release : Official Journal of the Controlled Release Society. 65: 149-71. PMID 10699278 DOI: 10.1016/S0168-3659(99)00249-7 |
0.362 |
|
| 2000 |
Dash PR, Read ML, Fisher KD, Howard KA, Wolfert M, Oupicky D, Subr V, Strohalm J, Ulbrich K, Seymour LW. Decreased binding to proteins and cells of polymeric gene delivery vectors surface modified with a multivalent hydrophilic polymer and retargeting through attachment of transferrin. The Journal of Biological Chemistry. 275: 3793-802. PMID 10660529 DOI: 10.1074/Jbc.275.6.3793 |
0.411 |
|
| 1999 |
Wolfert MA, Dash PR, Nazarova O, Oupicky D, Seymour LW, Smart S, Strohalm J, Ulbrich K. Polyelectrolyte vectors for gene delivery: influence of cationic polymer on biophysical properties of complexes formed with DNA. Bioconjugate Chemistry. 10: 993-1004. PMID 10563768 DOI: 10.1021/Bc990025R |
0.37 |
|
| 1999 |
Read ML, Etrych T, Ulbrich K, Seymour LW. Characterisation of the binding interaction between poly(L-lysine) and DNA using the fluorescamine assay in the preparation of non-viral gene delivery vectors. Febs Letters. 461: 96-100. PMID 10561503 DOI: 10.1016/S0014-5793(99)01435-0 |
0.409 |
|
| 1999 |
Oupický D, Konák C, Dash PR, Seymour LW, Ulbrich K. Effect of albumin and polyanion on the structure of DNA complexes with polycation containing hydrophilic nonionic block. Bioconjugate Chemistry. 10: 764-72. PMID 10502341 DOI: 10.1021/Bc990007+ |
0.357 |
|
| 1999 |
Dash PR, Read ML, Barrett LB, Wolfert MA, Seymour LW. Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery. Gene Therapy. 6: 643-50. PMID 10476224 DOI: 10.1038/Sj.Gt.3300843 |
0.364 |
|
| 1999 |
Soyez H, Seymour LW, Schacht E. Macromolecular derivatives of N,N-di-(2-chloroethyl)-4-phenylene diamine mustard. 2. In vitro cytotoxicity and in vivo anticancer efficacy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 57: 187-96. PMID 9971901 DOI: 10.1016/S0168-3659(98)00117-5 |
0.389 |
|
| 1999 |
Julyan PJ, Seymour LW, Ferry DR, Daryani S, Boivin CM, Doran J, David M, Anderson D, Christodoulou C, Young AM, Hesslewood S, Kerr DJ. Preliminary clinical study of the distribution of HPMA copolymers bearing doxorubicin and galactosamine. Journal of Controlled Release : Official Journal of the Controlled Release Society. 57: 281-90. PMID 9895415 DOI: 10.1016/S0168-3659(98)00124-2 |
0.336 |
|
| 1999 |
Carlisle RC, Read ML, Wolfert MA, Seymour LW. Self-assembling poly(L-lysine)/DNA complexes capable of integrin- mediated cellular uptake and gene expression Colloids and Surfaces B: Biointerfaces. 16: 261-272. DOI: 10.1016/S0927-7765(99)00077-6 |
0.388 |
|
| 1999 |
Ward CM, Fisher KD, Seymour LW. Turbidometric analysis of polyelectrolyte complexes formed between poly(L-lysine) and DNA Colloids and Surfaces B: Biointerfaces. 16: 253-260. DOI: 10.1016/S0927-7765(99)00076-4 |
0.369 |
|
| 1998 |
Baban DF, Seymour LW. Control of tumour vascular permeability. Advanced Drug Delivery Reviews. 34: 109-119. PMID 10837673 DOI: 10.1016/S0169-409X(98)00003-9 |
0.332 |
|
| 1998 |
Wolfert MA, Seymour LW. Chloroquine and amphipathic peptide helices show synergistic transfection in vitro. Gene Therapy. 5: 409-14. PMID 9614562 DOI: 10.1038/Sj.Gt.3300606 |
0.37 |
|
| 1998 |
Toncheva V, Wolfert MA, Dash PR, Oupicky D, Ulbrich K, Seymour LW, Schacht EH. Novel vectors for gene delivery formed by self-assembly of DNA with poly(L-lysine) grafted with hydrophilic polymers. Biochimica Et Biophysica Acta. 1380: 354-68. PMID 9555094 DOI: 10.1016/S0304-4165(98)00004-X |
0.401 |
|
| 1998 |
Hart SL, Arancibia-Cárcamo CV, Wolfert MA, Mailhos C, O'Reilly NJ, Ali RR, Coutelle C, George AJ, Harbottle RP, Knight AM, Larkin DF, Levinsky RJ, Seymour LW, Thrasher AJ, Kinnon C. Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vector. Human Gene Therapy. 9: 575-85. PMID 9525318 DOI: 10.1089/Hum.1998.9.4-575 |
0.361 |
|
| 1998 |
Konak C, Mrkvickova L, Nazarova O, Ulbrich K, Seymour LW. Formation of DNA complexes with diblock copolymers of poly(N-(2-hydroxypropyl)methacrylamide) and polycations Supramolecular Science. 5: 67-74. DOI: 10.1016/S0968-5677(97)00069-2 |
0.311 |
|
| 1997 |
Nichifor M, Schacht EH, Seymour LW, Anderson D, Shoaibi M. Cytotoxicity and anticancer activity of macromolecular prodrugs of 5-fluorouracil Journal of Bioactive and Compatible Polymers. 12: 265-281. DOI: 10.1177/088391159701200401 |
0.376 |
|
| 1997 |
Nichifor M, Schacht EH, Seymour LW. Polymeric prodrugs of 5-fluorouracil Journal of Controlled Release. 48: 165-178. DOI: 10.1016/S0168-3659(97)00048-5 |
0.361 |
|
| 1997 |
Dash PR, Toncheva V, Schacht E, Seymour LW. Synthetic polymers for vectorial delivery of DNA: Characterisation of polymer-DNA complexes by photon correlation spectroscopy and stability to nuclease degradation and disruption by polyanions in vitro Journal of Controlled Release. 48: 269-276. DOI: 10.1016/S0168-3659(97)00043-6 |
0.389 |
|
| 1997 |
Lemmouchi Y, Schacht E, Dejardin S, Vandorpe J, Seymour L. Biodegradable polyphosphazenes for drug delivery Macromolecular Symposia. 123: 103-112. DOI: 10.1002/Masy.19971230111 |
0.333 |
|
| 1996 |
Nichifor M, Schacht EH, Seymour LW. Macromolecular prodrugs of 5-fluorouracil. 2: Enzymatic degradation Journal of Controlled Release. 39: 79-92. DOI: 10.1016/0168-3659(95)00141-7 |
0.342 |
|
| 1996 |
Steyger PS, Baban DF, Brereton M, Ulbrich K, Seymour LW. Intratumoural Journal of Controlled Release. 39: 35-46. DOI: 10.1016/0168-3659(95)00131-X |
0.595 |
|
| 1996 |
Soyez H, Schacht E, De Marre A, Seymour LW. Polymeric prodrugs of mitomycin C Macromolecular Symposia. 103: 163-176. DOI: 10.1002/Masy.19961030117 |
0.344 |
|
| 1995 |
Seymour LW, Miyamoto Y, Maeda H, Brereton M, Strohalm J, Ulbrich K, Duncan R. Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier. European Journal of Cancer (Oxford, England : 1990). 31: 766-70. PMID 7640051 DOI: 10.1016/0959-8049(94)00514-6 |
0.304 |
|
| 1995 |
De Marre A, Soyez H, Schacht E, Shoaibi MA, Seymour LW, Rihova B. Synthesis and evaluation of macromolecular prodrugs of mitomycin C Journal of Controlled Release. 36: 87-97. DOI: 10.1016/0168-3659(95)00058-G |
0.345 |
|
| 1995 |
Cremers HFM, Lens JP, Seymour LW, Feijen J. Biodegradable ion-exchange microspheres based on modified polylysines Journal of Controlled Release. 36: 167-179. DOI: 10.1016/0168-3659(95)00048-D |
0.358 |
|
| 1994 |
Seymour LW, Ulbrich K, Steyger PS, Brereton M, Subr V, Strohalm J, Duncan R. Tumour tropism and anti-cancer efficacy of polymer-based doxorubicin prodrugs in the treatment of subcutaneous murine B16F10 melanoma. British Journal of Cancer. 70: 636-41. PMID 7917909 DOI: 10.1038/Bjc.1994.363 |
0.596 |
|
| 1994 |
Marre AD, Seymour LW, Schacht E. Evaluation of the hydrolytic and enzymatic stability of macromolecular Mitomycin C derivatives Journal of Controlled Release. 31: 89-97. DOI: 10.1016/0168-3659(94)90254-2 |
0.313 |
|
| 1993 |
Ulbrich K, Šubr V, Seymour LW, Duncan R. Novel biodegradable hydrogels prepared using the divinylic crosslinking agent N,O-dimethacryloylhydroxylamine. 1. Synthesis and characterisation of rates of gel degradation, and rate of release of model drugs, in vitro and in vivo Journal of Controlled Release. 24: 181-190. DOI: 10.1016/0168-3659(93)90177-7 |
0.33 |
|
| 1992 |
Duncan R, Seymour LW, O'Hare KB, Flanagan PA, Wedge S, Hume IC, Ulbrich K, Strohalm J, Subr V, Spreafico F, Grandi M, Ripamonti M, Farao M, Suarato A. Preclinical evaluation of polymer-bound doxorubicin Journal of Controlled Release. 19: 331-346. DOI: 10.1016/0168-3659(92)90088-9 |
0.382 |
|
| 1991 |
Yeung TK, Hopewell JW, Simmonds RH, Seymour LW, Duncan R, Bellini O, Grandi M, Spreafico F, Strohalm J, Ulbrich K. Reduced cardiotoxicity of doxorubicin given in the form of N-(2-hydroxypropyl)methacrylamide conjugates: and experimental study in the rat. Cancer Chemotherapy and Pharmacology. 29: 105-11. PMID 1760851 DOI: 10.1007/Bf00687318 |
0.345 |
|
| 1991 |
Seymour LW, Ulbrich K, Wedge SR, Hume IC, Strohalm J, Duncan R. N-(2-hydroxypropyl)methacrylamide copolymers targeted to the hepatocyte galactose-receptor: pharmacokinetics in DBA2 mice. British Journal of Cancer. 63: 859-66. PMID 1648946 DOI: 10.1038/Bjc.1991.190 |
0.357 |
|
| 1988 |
Duncan R, Seymour LW, Ulbrich K, Kopecek J. Soluble synthetic polymers for targeting and controlled release of anticancer agents, particularly anthracycline antibiotics Journal of Bioactive and Compatible Polymers. 3: 4-15. DOI: 10.1177/088391158800300102 |
0.328 |
|
| 1987 |
Seymour LW, Duncan R, Strohalm J, Kopecek J. Effect of molecular weight (Mw) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats. Journal of Biomedical Materials Research. 21: 1341-58. PMID 3680316 DOI: 10.1002/Jbm.820211106 |
0.313 |
|
| 1987 |
Seymour LW, Duncan R, Kopecková P, Kopecek J. Daunomycin- and adriamycin-N-(2-hydroxypropyl)methacrylamide copolymer conjugates; toxicity reduction by improved drug-delivery. Cancer Treatment Reviews. 14: 319-27. PMID 3326668 DOI: 10.1016/0305-7372(87)90024-7 |
0.318 |
|
| 1987 |
Seymour LW, Duncan R, Kopeckova P, Kopecek J. Potential of sugar residues attached to N-(2-hydroxypropyl)methacrylamide copolymers as targeting groups for the selective delivery of drugs Journal of Bioactive and Compatible Polymers. 2: 97-119. DOI: 10.1177/088391158700200201 |
0.366 |
|
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