Year |
Citation |
Score |
2023 |
Miller KA, Degan S, Wang Y, Cohen J, Ku SY, Goodrich DW, Gelman IH. Correction: PTEN-regulated PI3K-p110 and AKT isoform plasticity controls metastatic prostate cancer progression. Oncogene. PMID 38097735 DOI: 10.1038/s41388-023-02920-2 |
0.343 |
|
2023 |
Miller KA, Degan S, Wang Y, Cohen J, Ku SY, Goodrich DW, Gelman IH. PTEN-regulated PI3K-p110 and AKT isoform plasticity controls metastatic prostate cancer progression. Oncogene. PMID 37875657 DOI: 10.1038/s41388-023-02875-4 |
0.425 |
|
2023 |
Gelman IH. Metastasis suppressor genes in clinical practice: are they druggable? Cancer Metastasis Reviews. 42: 1169-1188. PMID 37749308 DOI: 10.1007/s10555-023-10135-w |
0.365 |
|
2023 |
Miller K, Degan S, Wang Y, Cohen J, Ku SY, Goodrich D, Gelman I. PTEN regulated PI3K-p110 and AKT isoform plasticity controls metastatic prostate cancer progression. Research Square. PMID 37292818 DOI: 10.21203/rs.3.rs-2924750/v1 |
0.421 |
|
2022 |
Zhang J, Gelman IH, Qu J, Hochwald SN. Phosphohistidine signaling promotes FAK-RB1 interaction and growth factor-independent proliferation of esophageal squamous cell carcinoma. Oncogene. PMID 36513743 DOI: 10.1038/s41388-022-02568-4 |
0.327 |
|
2022 |
Katsuta E, Gil-Moore M, Moore J, Yousif M, Adjei AA, Ding Y, Caserta J, Baldino CM, Lee KP, Gelman IH, Takabe K, Opyrchal M. Targeting PIM2 by JP11646 results in significant antitumor effects in solid tumors. International Journal of Oncology. 61. PMID 35920189 DOI: 10.3892/ijo.2022.5404 |
0.369 |
|
2021 |
Degan SE, Gelman IH. Emerging Roles for AKT Isoform Preference in Cancer Progression Pathways. Molecular Cancer Research : McR. PMID 33931488 DOI: 10.1158/1541-7786.MCR-20-1066 |
0.382 |
|
2019 |
Zhang J, Gelman IH, Katsuta E, Liang Y, Wang X, Li J, Qu J, Yan L, Takabe K, Hochwald SN. Glucose drives growth factor-independent esophageal cancer proliferation via phosphohistidine-FAK signaling. Cellular and Molecular Gastroenterology and Hepatology. PMID 30836148 DOI: 10.1016/J.Jcmgh.2019.02.009 |
0.436 |
|
2019 |
McGrath JE, Panzica L, Ransom R, Withers HG, Gelman IH. Identification of genes regulating breast cancer dormancy in 3D bone endosteal niche cultures. Molecular Cancer Research : McR. PMID 30651373 DOI: 10.1158/1541-7786.Mcr-18-0956 |
0.386 |
|
2019 |
Gandhi S, Gil M, Khoury T, Takabe K, Puzanov I, Gelman I, D'Assoro A, Opyrchal M. Abstract P2-06-17: A novel interaction of AURKA with MAPK pathway in breast cancer cells as a potential therapeutic target Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P2-06-17 |
0.479 |
|
2018 |
Lee HS, Choi J, Son T, Lee EJ, Kim JG, Ryu SH, Lee D, Jang MK, Yu E, Chung YH, Gelman IH, Kim KW. A-kinase anchoring protein 12 is downregulated in human hepatocellular carcinoma and its deficiency in mice aggravates thioacetamide-induced liver injury. Oncology Letters. 16: 5907-5915. PMID 30344741 DOI: 10.3892/Ol.2018.9396 |
0.37 |
|
2018 |
Mahpour A, Scruggs BS, Smiraglia D, Ouchi T, Gelman IH. A methyl-sensitive element induces bidirectional transcription in TATA-less CpG island-associated promoters. Plos One. 13: e0205608. PMID 30332484 DOI: 10.1371/Journal.Pone.0205608 |
0.306 |
|
2018 |
Muramatsu M, Akakura S, Gao L, Peresie J, Balderman B, Gelman IH. SSeCKS/Akap12 suppresses metastatic melanoma lung colonization by attenuating Src-mediated pre-metastatic niche crosstalk. Oncotarget. 9: 33515-33527. PMID 30323895 DOI: 10.18632/oncotarget.26067 |
0.392 |
|
2018 |
Smolinski MP, Bu Y, Clements J, Gelman IH, Hegab T, Cutler DL, Fang JWS, Fetterly G, Kwan R, Barnett A, Lau JYN, Hangauer DG. Discovery of Novel Dual Mechanism of Action Src Signaling and Tubulin Polymerization Inhibitors (KX2-391 and KX2-361). Journal of Medicinal Chemistry. PMID 29617135 DOI: 10.1021/Acs.Jmedchem.8B00164 |
0.585 |
|
2018 |
Maki T, Choi YK, Miyamoto N, Shindo A, Liang AC, Ahn BJ, Mandeville ET, Kaji S, Itoh K, Seo JH, Gelman IH, Lok J, Takahashi R, Kim KW, Lo EH, et al. A-Kinase Anchor Protein 12 is Required for Oligodendrocyte Differentiation in Adult White Matter. Stem Cells (Dayton, Ohio). PMID 29314444 DOI: 10.1002/Stem.2771 |
0.37 |
|
2018 |
Gil M, Chidambaram A, Khoury T, Takabe K, Puzanov I, Gelman IH, D’Assoro AB, Galanis E, Opyrchal M. Abstract A60: AURKA interaction with MEK1/2 complex and its role in promoting breast cancer cell metastasis Molecular Cancer Research. 16. DOI: 10.1158/1557-3125.Advbc17-A60 |
0.509 |
|
2017 |
Muramatsu M, Gao L, Peresie J, Balderman B, Akakura S, Gelman IH. SSeCKS/AKAP12 scaffolding functions suppress B16F10-induced peritoneal metastasis by attenuating CXCL9/10 secretion by resident fibroblasts. Oncotarget. 8: 70281-70298. PMID 29050279 DOI: 10.18632/Oncotarget.20092 |
0.515 |
|
2017 |
Zhang Y, Shen H, Withers HG, Yang N, Denson KE, Mussell AL, Truskinovsky A, Fan Q, Gelman IH, Frangou C, Zhang J. VGLL4 Selectively Represses YAP-Dependent Gene Induction and Tumorigenic Phenotypes in Breast Cancer. Scientific Reports. 7: 6190. PMID 28733631 DOI: 10.1038/S41598-017-06227-7 |
0.424 |
|
2017 |
Withers HG, Gelman IH. Abstract LB-148: Characterization of an off-target RNAi genomic screen hit identifiesGPRC6Aas a novel suppressor of metastatic chemotaxis and invasiveness Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-148 |
0.348 |
|
2017 |
Gil M, Chidambaram A, Khoury T, Takabe K, Puzanov I, Gelman I, D’Assoro A, Opyrchal M. Abstract 2123: Inhibition of AURKA induces Raf1-independent activation of MAPK pathway in breast cancer cells Cancer Research. 77: 2123-2123. DOI: 10.1158/1538-7445.Am2017-2123 |
0.3 |
|
2016 |
Chattopadhyay I, Wang J, Qin M, Gao L, Holtz R, Vessella RL, Leach RW, Gelman IH. Src promotes castration-recurrent prostate cancer through androgen receptor-dependent canonical and non-canonical transcriptional signatures. Oncotarget. PMID 28055971 DOI: 10.18632/Oncotarget.14401 |
0.519 |
|
2016 |
Gelman IH. How the TRAMP Model Revolutionized the Study of Prostate Cancer Progression. Cancer Research. 76: 6137-6139. PMID 27803100 DOI: 10.1158/0008-5472.Can-16-2636 |
0.374 |
|
2016 |
Shourideh M, Azabdaftari G, Attwood K, DePriest A, Wadosky KM, Gillard BM, Karasik E, Heemers H, Kyprianou N, Gelman IH, Corey E, Vessella RL, Mohler JL, Koochekpour S. GRM1 is An Androgen-Regulated Gene and its Expression Correlates with Prostate Cancer Progression in Pre-Clinical Models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27458247 DOI: 10.1158/1078-0432.Ccr-16-0137 |
0.441 |
|
2016 |
Ko H, AKakura S, Peresie J, Goodrich D, Foster B, Gelman IH. Abstract B32: Transgenic model for early prostate cancer metastasis to the lymph nodes Cancer Research. 76. DOI: 10.1158/1538-7445.Tummet15-B32 |
0.61 |
|
2016 |
Withers HG, Ransom R, Gelman IH. Abstract LB-167: Off-target analysis of RNAi screens identifies microRNA seed sequence contributing to metastatic invasion Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-167 |
0.35 |
|
2015 |
Hehnly H, Canton D, Bucko P, Langeberg LK, Ogier L, Gelman I, Santana LF, Wordeman L, Scott JD. A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells. Elife. 4: e09384. PMID 26406118 DOI: 10.7554/Elife.09384 |
0.412 |
|
2015 |
Dwyer SF, Gao L, Gelman IH. Identification of novel focal adhesion kinase substrates: role for FAK in NFκB signaling. International Journal of Biological Sciences. 11: 404-10. PMID 25798060 DOI: 10.7150/Ijbs.10273 |
0.47 |
|
2015 |
Hehnly H, Canton D, Bucko P, Langeberg LK, Ogier L, Gelman I, Santana LF, Wordeman L, Scott JD. Author response: A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells Elife. DOI: 10.7554/Elife.09384.018 |
0.353 |
|
2014 |
Ko HK, Guo LW, Su B, Gao L, Gelman IH. Suppression of chemotaxis by SSeCKS via scaffolding of phosphoinositol phosphates and the recruitment of the Cdc42 GEF, Frabin, to the leading edge. Plos One. 9: e111534. PMID 25356636 DOI: 10.1371/Journal.Pone.0111534 |
0.694 |
|
2014 |
Gelman IH, Peresie J, Eng KH, Foster BA. Differential requirement for Src family tyrosine kinases in the initiation, progression, and metastasis of prostate cancer. Molecular Cancer Research : McR. 12: 1470-9. PMID 25053806 DOI: 10.1158/1541-7786.Mcr-13-0490-T |
0.512 |
|
2014 |
Su B, Gao L, Baranowski C, Gillard B, Wang J, Ransom R, Ko HK, Gelman IH. A genome-wide RNAi screen identifies FOXO4 as a metastasis-suppressor through counteracting PI3K/AKT signal pathway in prostate cancer. Plos One. 9: e101411. PMID 24983969 DOI: 10.1371/Journal.Pone.0101411 |
0.706 |
|
2014 |
Gelman IH. Androgen receptor activation in castration-recurrent prostate cancer: the role of Src-family and Ack1 tyrosine kinases. International Journal of Biological Sciences. 10: 620-6. PMID 24948875 DOI: 10.7150/Ijbs.8264 |
0.477 |
|
2014 |
Cha JH, Wee HJ, Seo JH, Ahn BJ, Park JH, Yang JM, Lee SW, Kim EH, Lee OH, Heo JH, Lee HJ, Gelman IH, Arai K, Lo EH, Kim KW. AKAP12 mediates barrier functions of fibrotic scars during CNS repair. Plos One. 9: e94695. PMID 24760034 DOI: 10.1371/Journal.Pone.0094695 |
0.352 |
|
2014 |
Ko HK, Akakura S, Peresie J, Goodrich DW, Foster BA, Gelman IH. A transgenic mouse model for early prostate metastasis to lymph nodes. Cancer Research. 74: 945-53. PMID 24492704 DOI: 10.1158/0008-5472.CAN-13-1157 |
0.632 |
|
2013 |
Su B, Gillard B, Gao L, Eng KH, Gelman IH. Src controls castration recurrence of CWR22 prostate cancer xenografts. Cancer Medicine. 2: 784-92. PMID 24403252 DOI: 10.1002/Cam4.144 |
0.508 |
|
2013 |
Smeets B, Boor P, Dijkman H, Sharma SV, Jirak P, Mooren F, Berger K, Bornemann J, Gelman IH, Floege J, van der Vlag J, Wetzels JF, Moeller MJ. Proximal tubular cells contain a phenotypically distinct, scattered cell population involved in tubular regeneration. The Journal of Pathology. 229: 645-59. PMID 23124355 DOI: 10.1002/Path.4125 |
0.301 |
|
2013 |
Su B, Gao L, Meng F, Guo LW, Rothschild J, Gelman IH. Adhesion-mediated cytoskeletal remodeling is controlled by the direct scaffolding of Src from FAK complexes to lipid rafts by SSeCKS/AKAP12 Oncogene. 32: 2016-2026. PMID 22710722 DOI: 10.1038/Onc.2012.218 |
0.575 |
|
2013 |
Liu X, Yang N, Figel SA, Wilson KE, Morrison CD, Gelman IH, Zhang J. PTPN14 interacts with and negatively regulates the oncogenic function of YAP. Oncogene. 32: 1266-73. PMID 22525271 DOI: 10.1038/Onc.2012.147 |
0.772 |
|
2013 |
Ko H, Akakura S, Peresie J, Goodrich DW, Foster BA, Gelman IH. Abstract 3863: Transgenic model for early prostate metastasis to the lymph nodes. Cancer Research. 73: 3863-3863. DOI: 10.1158/1538-7445.Am2013-3863 |
0.671 |
|
2013 |
Sudol M, Gelman IH, Zhang J. YAP1 uses its modular protein domains and conserved sequence motifs to orchestrate diverse repertoires of signaling The Hippo Signaling Pathway and Cancer. 2147483647: 53-70. DOI: 10.1007/978-1-4614-6220-0_4 |
0.341 |
|
2012 |
Havekes R, Canton DA, Park AJ, Huang T, Nie T, Day JP, Guercio LA, Grimes Q, Luczak V, Gelman IH, Baillie GS, Scott JD, Abel T. Gravin orchestrates protein kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 18137-49. PMID 23238728 DOI: 10.1523/Jneurosci.3612-12.2012 |
0.354 |
|
2012 |
Akakura S, Gelman IH. Pivotal Role of AKAP12 in the Regulation of Cellular Adhesion Dynamics: Control of Cytoskeletal Architecture, Cell Migration, and Mitogenic Signaling. Journal of Signal Transduction. 2012: 529179. PMID 22811901 DOI: 10.1155/2012/529179 |
0.503 |
|
2012 |
Gelman IH. Suppression of tumor and metastasis progression through the scaffolding functions of SSeCKS/Gravin/AKAP12. Cancer Metastasis Reviews. 31: 493-500. PMID 22684366 DOI: 10.1007/S10555-012-9360-1 |
0.53 |
|
2012 |
Ho B, Olson G, Figel S, Gelman I, Cance WG, Golubovskaya VM. Nanog increases focal adhesion kinase (FAK) promoter activity and expression and directly binds to FAK protein to be phosphorylated. The Journal of Biological Chemistry. 287: 18656-73. PMID 22493428 DOI: 10.1074/Jbc.M111.322883 |
0.784 |
|
2012 |
Golubovskaya VM, Figel S, Ho BT, Johnson CP, Yemma M, Huang G, Zheng M, Nyberg C, Magis A, Ostrov DA, Gelman IH, Cance WG. A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl)-3, 5, 7-triaza-1-azoniatricyclo [3.3.1.1(3,7)]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, clonogenicity and tumor growth in vivo. Carcinogenesis. 33: 1004-13. PMID 22402131 DOI: 10.1093/Carcin/Bgs120 |
0.784 |
|
2012 |
Burnworth B, Pippin J, Karna P, Akakura S, Krofft R, Zhang G, Hudkins K, Alpers CE, Smith K, Shankland SJ, Gelman IH, Nelson PJ. SSeCKS sequesters cyclin D1 in glomerular parietal epithelial cells and influences proliferative injury in the glomerulus. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 499-510. PMID 22249313 DOI: 10.1038/Labinvest.2011.199 |
0.426 |
|
2012 |
Kartal-Kaess M, Cimmino L, Infantino S, Yabas M, Zhang J, Tuohey L, Gelman IH, Scott JD, Nutt SL, Enders A, Tarlinton D, Dickins RA. RNAi Screening Identifies A Novel Role for A-Kinase Anchoring Protein 12 (AKAP12) in B Cell Development and Function Blood. 120: 855-855. DOI: 10.1182/Blood.V120.21.855.855 |
0.435 |
|
2012 |
Ko H, Akakura S, Peresie J, Foster B, Gelman IH. Abstract C56: The combined loss of SSeCKS/Gravin/AKAP12 and Rb in the prostate promotes spontaneous lymph node metastases with basal-luminal transitional phenotypes Cancer Research. 72. DOI: 10.1158/1538-7445.Prca2012-C56 |
0.671 |
|
2012 |
Liu X, Yang N, Figel SA, Wilson KE, Morrison CD, Gelman IH, Zhang J. Abstract LB-520: PTPN14 interacts with and negatively regulates the oncogenic function of YAP Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-520 |
0.506 |
|
2012 |
Akakura S, Muramatsu M, Ko HK, Gelman IH. Abstract 3429: AKAP12/SSeCKS inhibits peritoneal metastasis by regulating chemokine production Cancer Research. 72: 3429-3429. DOI: 10.1158/1538-7445.Am2012-3429 |
0.682 |
|
2011 |
Guo LW, Gao L, Rothschild J, Su B, Gelman IH. Control of protein kinase C activity, phorbol ester-induced cytoskeletal remodeling, and cell survival signals by the scaffolding protein SSeCKS/GRAVIN/AKAP12 Journal of Biological Chemistry. 286: 38356-38366. PMID 21903576 DOI: 10.1074/Jbc.M111.258830 |
0.495 |
|
2011 |
Gelman IH. Src-family tyrosine kinases as therapeutic targets in advanced cancer. Frontiers in Bioscience (Elite Edition). 3: 801-7. PMID 21622091 DOI: 10.2741/E287 |
0.528 |
|
2011 |
Streb JW, Long X, Lee TH, Sun Q, Kitchen CM, Georger MA, Slivano OJ, Blaner WS, Carr DW, Gelman IH, Miano JM. Retinoid-induced expression and activity of an immediate early tumor suppressor gene in vascular smooth muscle cells. Plos One. 6: e18538. PMID 21483686 DOI: 10.1371/Journal.Pone.0018538 |
0.436 |
|
2011 |
Figel S, Gelman IH. Focal adhesion kinase controls prostate cancer progression via intrinsic kinase and scaffolding functions. Anti-Cancer Agents in Medicinal Chemistry. 11: 607-16. PMID 21355844 DOI: 10.2174/187152011796817646 |
0.79 |
|
2011 |
Akakura S, Bouchard R, Bshara W, Morrison C, Gelman IH. Carcinogen-induced squamous papillomas and oncogenic progression in the absence of the SSeCKS/AKAP12 metastasis suppressor correlate with FAK upregulation. International Journal of Cancer. Journal International Du Cancer. 129: 2025-31. PMID 21128249 DOI: 10.1002/Ijc.25828 |
0.486 |
|
2011 |
Bu Y, Gao L, Gelman IH. Role for transcription factor TFII-I in the suppression of SSeCKS/Gravin/Akap12 transcription by Src. International Journal of Cancer. Journal International Du Cancer. 128: 1836-42. PMID 20568114 DOI: 10.1002/Ijc.25524 |
0.66 |
|
2011 |
Su B, Baranowski C, Gelman IH. Abstract 1449: A loss-of-function shRNA library screen for the cell invasion-suppressing genes in LNCaP prostate cancer cells Cancer Research. 71: 1449-1449. DOI: 10.1158/1538-7445.Am2011-1449 |
0.473 |
|
2010 |
Gelman IH, Sudol M. Introduction: hanafusa memorial issue, part 2. Genes & Cancer. 1: 1163. PMID 21785489 DOI: 10.1177/1947601911407630 |
0.46 |
|
2010 |
Gelman IH, Sudol M. Introduction: hanafusa memorial issue. Genes & Cancer. 1: 1088. PMID 21785488 DOI: 10.1177/1947601911401912 |
0.414 |
|
2010 |
Gelman IH. Emerging Roles for SSeCKS/Gravin/AKAP12 in the Control of Cell Proliferation, Cancer Malignancy, and Barriergenesis. Genes & Cancer. 1: 1147-56. PMID 21779438 DOI: 10.1177/1947601910392984 |
0.452 |
|
2010 |
Akakura S, Nochajski P, Gao L, Sotomayor P, Matsui S, Gelman IH. Rb-dependent cellular senescence, multinucleation and susceptibility to oncogenic transformation through PKC scaffolding by SSeCKS/AKAP12. Cell Cycle (Georgetown, Tex.). 9: 4656-65. PMID 21099353 DOI: 10.4161/Cc.9.23.13974 |
0.547 |
|
2010 |
Su B, Bu Y, Engelberg D, Gelman IH. SSeCKS/Gravin/AKAP12 inhibits cancer cell invasiveness and chemotaxis by suppressing a protein kinase C- Raf/MEK/ERK pathway. The Journal of Biological Chemistry. 285: 4578-86. PMID 20018890 DOI: 10.1074/Jbc.M109.073494 |
0.716 |
|
2010 |
Bu Y, Gao L, Hangauer D, Gelman IH. Abstract 2534: Suppression of prostate cancer growth by the Src signaling inhibitor, KXO1 (KX2-391) Cancer Research. 70: 2534-2534. DOI: 10.1158/1538-7445.Am10-2534 |
0.68 |
|
2010 |
Bu Y, Smolinski M, Qu J, Kazim L, Gelman I, Dyster L, Hangauer D. Abstract 2487: Mechanism of action KX01 (KX2-391), a novel tubulin polymerization and Src signaling inhibitor proceeding to Phase II clinical trials Cancer Research. 70: 2487-2487. DOI: 10.1158/1538-7445.Am10-2487 |
0.647 |
|
2009 |
Sachdev S, Bu Y, Gelman IH. Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion. Bmc Cancer. 9: 12. PMID 19138410 DOI: 10.1186/1471-2407-9-12 |
0.673 |
|
2009 |
Lau GM, Lau GM, Yu GL, Gelman IH, Gutowski A, Hangauer D, Fang JW. Expression of Src and FAK in hepatocellular carcinoma and the effect of Src inhibitors on hepatocellular carcinoma in vitro. Digestive Diseases and Sciences. 54: 1465-74. PMID 18979199 DOI: 10.1007/S10620-008-0519-0 |
0.358 |
|
2008 |
Akakura S, Huang C, Nelson PJ, Foster B, Gelman IH. Loss of the SSeCKS/Gravin/AKAP12 gene results in prostatic hyperplasia. Cancer Research. 68: 5096-103. PMID 18593908 DOI: 10.1158/0008-5472.Can-07-5619 |
0.483 |
|
2007 |
Bu Y, Gelman IH. v-Src-mediated down-regulation of SSeCKS metastasis suppressor gene promoter by the recruitment of HDAC1 into a USF1-Sp1-Sp3 complex. The Journal of Biological Chemistry. 282: 26725-39. PMID 17626016 DOI: 10.1074/Jbc.M702885200 |
0.591 |
|
2006 |
Chaar Z, O'reilly P, Gelman I, Sabourin LA. v-Src-dependent down-regulation of the Ste20-like kinase SLK by casein kinase II. The Journal of Biological Chemistry. 281: 28193-9. PMID 16837460 DOI: 10.1074/Jbc.M605665200 |
0.471 |
|
2006 |
Su B, Zheng Q, Vaughan MM, Bu Y, Gelman IH. SSeCKS metastasis-suppressing activity in MatLyLu prostate cancer cells correlates with vascular endothelial growth factor inhibition. Cancer Research. 66: 5599-607. PMID 16740695 DOI: 10.1158/0008-5472.Can-05-4123 |
0.648 |
|
2006 |
Liu Y, Gao L, Gelman IH. SSeCKS/Gravin/AKAP12 attenuates expression of proliferative and angiogenic genes during suppression of v-Src-induced oncogenesis. Bmc Cancer. 6: 105. PMID 16638134 DOI: 10.1186/1471-2407-6-105 |
0.482 |
|
2006 |
Gelman IH, Gao L. SSeCKS/Gravin/AKAP12 metastasis suppressor inhibits podosome formation via RhoA- and Cdc42-dependent pathways. Molecular Cancer Research : McR. 4: 151-8. PMID 16547152 DOI: 10.1158/1541-7786.Mcr-05-0252 |
0.527 |
|
2005 |
Moissoglu K, Sachdev S, Gelman IH. Enhanced v-Src-induced oncogenic transformation in the absence of focal adhesion kinase is mediated by phosphatidylinositol 3-kinase. Biochemical and Biophysical Research Communications. 330: 673-84. PMID 15809050 DOI: 10.1016/J.Bbrc.2005.03.025 |
0.513 |
|
2004 |
Streb JW, Kitchen CM, Gelman IH, Miano JM. Multiple promoters direct expression of three AKAP12 isoforms with distinct subcellular and tissue distribution profiles. The Journal of Biological Chemistry. 279: 56014-23. PMID 15496411 DOI: 10.1074/Jbc.M408828200 |
0.395 |
|
2004 |
Gherardi D, D'Agati V, Chu TH, Barnett A, Gianella-Borradori A, Gelman IH, Nelson PJ. Reversal of collapsing glomerulopathy in mice with the cyclin-dependent kinase inhibitor CYC202. Journal of the American Society of Nephrology : Jasn. 15: 1212-22. PMID 15100361 DOI: 10.1097/01.Asn.0000124672.41036.F4 |
0.37 |
|
2003 |
Moissoglu K, Gelman IH. v-Src rescues actin-based cytoskeletal architecture and cell motility and induces enhanced anchorage independence during oncogenic transformation of focal adhesion kinase-null fibroblasts. The Journal of Biological Chemistry. 278: 47946-59. PMID 14500722 DOI: 10.1074/Jbc.M302720200 |
0.496 |
|
2003 |
Gelman IH. Pyk 2 FAKs, any two FAKs. Cell Biology International. 27: 507-10. PMID 12842089 DOI: 10.1016/S1065-6995(03)00078-7 |
0.378 |
|
2003 |
Lee SW, Kim WJ, Choi YK, Song HS, Son MJ, Gelman IH, Kim YJ, Kim KW. SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier. Nature Medicine. 9: 900-6. PMID 12808449 DOI: 10.1038/Nm889 |
0.313 |
|
2003 |
Nelson PJ, D'Agati VD, Gries JM, Suarez JR, Gelman IH. Amelioration of nephropathy in mice expressing HIV-1 genes by the cyclin-dependent kinase inhibitor flavopiridol. The Journal of Antimicrobial Chemotherapy. 51: 921-9. PMID 12654740 DOI: 10.1093/Jac/Dkg175 |
0.307 |
|
2003 |
Gelman IH. Isolation of novel substrates using a tyrosine kinase overlay/in situ assay. Methods in Molecular Biology (Clifton, N.J.). 218: 133-41. PMID 12616718 DOI: 10.1385/1-59259-356-9:133 |
0.427 |
|
2002 |
Gelman IH. The role of SSeCKS/gravin/AKAP12 scaffolding proteins in the spaciotemporal control of signaling pathways in oncogenesis and development . Frontiers in Bioscience : a Journal and Virtual Library. 7: d1782-97. PMID 12133808 DOI: 10.2741/Gelman |
0.437 |
|
2002 |
Xia W, Gelman IH. Mitogen-induced, FAK-dependent tyrosine phosphorylation of the SSeCKS scaffolding protein. Experimental Cell Research. 277: 139-51. PMID 12083796 DOI: 10.1006/Excr.2002.5560 |
0.504 |
|
2002 |
Lin X, Gelman IH. Calmodulin and cyclin D anchoring sites on the Src-suppressed C kinase substrate, SSeCKS. Biochemical and Biophysical Research Communications. 290: 1368-75. PMID 11820772 DOI: 10.1006/Bbrc.2002.6357 |
0.417 |
|
2000 |
Lin X, Nelson P, Gelman IH. SSeCKS, a Major Protein Kinase C Substrate with Tumor Suppressor Activity, Regulates G1→S Progression by Controlling the Expression and Cellular Compartmentalization of Cyclin D Molecular and Cellular Biology. 20: 7259-7272. PMID 10982843 DOI: 10.1128/Mcb.20.19.7259-7272.2000 |
0.535 |
|
2000 |
Gelman IH, Tombler E, Vargas J. A role for SSeCKS, a major protein kinase C substrate with tumour suppressor activity, in cytoskeletal architecture, formation of migratory processes, and cell migration during embryogenesis. The Histochemical Journal. 32: 13-26. PMID 10805381 DOI: 10.1023/A:1003950027529 |
0.426 |
|
1998 |
Gelman IH, Lee K, Tombler E, Gordon R, Lin X. Control of cytoskeletal architecture by the src-suppressed C kinase substrate, SSeCKS. Cytoskeleton. 41: 1-17. PMID 9744295 DOI: 10.1002/(Sici)1097-0169(1998)41:1<1::Aid-Cm1>3.0.Co;2-J |
0.48 |
|
1997 |
Nelson PJ, Gelman IH. Cell-cycle regulated expression and serine phosphorylation of the myristylated protein kinase C substrate, SSeCKS: Correlation with culture confluency, cell cycle phase and serum response Molecular and Cellular Biochemistry. 175: 233-241. PMID 9350056 DOI: 10.1023/A:1006836003758 |
0.459 |
|
1996 |
Lin X, Tombler E, Nelson PJ, Ross M, Gelman IH. A Novel src- and ras-suppressed Protein Kinase C Substrate Associated with Cytoskeletal Architecture Journal of Biological Chemistry. 271: 28430-28438. PMID 8910468 DOI: 10.1074/Jbc.271.45.28430 |
0.456 |
|
1995 |
Lin X, Nelson PJ, Frankfort B, Tombler E, Johnson R, Gelman IH. Isolation and characterization of a novel mitogenic regulatory gene, 322, which is transcriptionally suppressed in cells transformed by src and ras. Molecular and Cellular Biology. 15: 2754-2762. PMID 7739556 DOI: 10.1128/Mcb.15.5.2754 |
0.379 |
|
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