John W. Baynes - Publications

Affiliations: 
1976-2006 Chemistry and Biochemistry University of South Carolina, Columbia, SC 
Area:
Analytical Chemistry, Biochemistry
Website:
https://sc.edu/study/colleges_schools/chemistry_and_biochemistry/our_people/students_researchers_emeritus/baynes_john.php

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Year Citation  Score
2014 Merkley ED, Metz TO, Smith RD, Baynes JW, Frizzell N. The succinated proteome. Mass Spectrometry Reviews. 33: 98-109. PMID 24115015 DOI: 10.1002/Mas.21382  0.63
2012 Frizzell N, Thomas SA, Carson JA, Baynes JW. Mitochondrial stress causes increased succination of proteins in adipocytes in response to glucotoxicity. The Biochemical Journal. 445: 247-54. PMID 22524437 DOI: 10.1042/Bj20112142  0.325
2012 Nagai R, Murray DB, Metz TO, Baynes JW. Chelation: a fundamental mechanism of action of AGE inhibitors, AGE breakers, and other inhibitors of diabetes complications. Diabetes. 61: 549-59. PMID 22354928 DOI: 10.2337/Db11-1120  0.601
2012 Thomas SA, Storey KB, Baynes JW, Frizzell N. Tissue distribution of S-(2-succino)cysteine (2SC), a biomarker of mitochondrial stress in obesity and diabetes. Obesity (Silver Spring, Md.). 20: 263-9. PMID 22134201 DOI: 10.1038/Oby.2011.340  0.308
2011 Frizzell N, Lima M, Baynes JW. Succination of proteins in diabetes. Free Radical Research. 45: 101-9. PMID 20964553 DOI: 10.3109/10715762.2010.524643  0.337
2010 Nagai R, Nagai M, Shimasaki S, Baynes JW, Fujiwara Y. Citric acid inhibits development of cataracts, proteinuria and ketosis in streptozotocin (type 1) diabetic rats. Biochemical and Biophysical Research Communications. 393: 118-22. PMID 20117096 DOI: 10.1016/J.Bbrc.2010.01.095  0.333
2009 Frizzell N, Rajesh M, Jepson MJ, Nagai R, Carson JA, Thorpe SR, Baynes JW. Succination of thiol groups in adipose tissue proteins in diabetes: succination inhibits polymerization and secretion of adiponectin. The Journal of Biological Chemistry. 284: 25772-81. PMID 19592500 DOI: 10.1074/Jbc.M109.019257  0.327
2009 Zhang Q, Ames JM, Smith RD, Baynes JW, Metz TO. A perspective on the Maillard reaction and the analysis of protein glycation by mass spectrometry: probing the pathogenesis of chronic disease. Journal of Proteome Research. 8: 754-69. PMID 19093874 DOI: 10.1021/Pr800858H  0.636
2009 Zhang Q, Ames JM, Smith RD, Baynes JW, Metz TO. A perspective on the maillard reaction and the analysis of protein glycation by mass spectrometry Journal of Proteome Research. 8: 754-769. DOI: 10.1021/Pr80085Bh  0.544
2008 Zhang Q, Schepmoes AA, Brock JW, Wu S, Moore RJ, Purvine SO, Baynes JW, Smith RD, Metz TO. Improved methods for the enrichment and analysis of glycated peptides. Analytical Chemistry. 80: 9822-9. PMID 18989935 DOI: 10.1021/Ac801704J  0.688
2008 Blatnik M, Thorpe SR, Baynes JW. Succination of proteins by fumarate: mechanism of inactivation of glyceraldehyde-3-phosphate dehydrogenase in diabetes. Annals of the New York Academy of Sciences. 1126: 272-5. PMID 18448829 DOI: 10.1196/Annals.1433.047  0.781
2008 Mera K, Nagai M, Brock JW, Fujiwara Y, Murata T, Maruyama T, Baynes JW, Otagiri M, Nagai R. Glutaraldehyde is an effective cross-linker for production of antibodies against advanced glycation end-products. Journal of Immunological Methods. 334: 82-90. PMID 18353354 DOI: 10.1016/J.Jim.2008.02.002  0.528
2008 Brock JW, Jenkins AJ, Lyons TJ, Klein RL, Yim E, Lopes-Virella M, Carter RE, Thorpe SR, Baynes JW. Increased methionine sulfoxide content of apoA-I in type 1 diabetes. Journal of Lipid Research. 49: 847-55. PMID 18202432 DOI: 10.1194/Jlr.M800015-Jlr200  0.59
2008 Blatnik M, Frizzell N, Thorpe SR, Baynes JW. Inactivation of glyceraldehyde-3-phosphate dehydrogenase by fumarate in diabetes: formation of S-(2-succinyl)cysteine, a novel chemical modification of protein and possible biomarker of mitochondrial stress. Diabetes. 57: 41-9. PMID 17934141 DOI: 10.2337/Db07-0838  0.772
2007 Nagai R, Brock JW, Blatnik M, Baatz JE, Bethard J, Walla MD, Thorpe SR, Baynes JW, Frizzell N. Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress. The Journal of Biological Chemistry. 282: 34219-28. PMID 17726021 DOI: 10.1074/Jbc.M703551200  0.814
2007 Zhang Q, Tang N, Brock JW, Mottaz HM, Ames JM, Baynes JW, Smith RD, Metz TO. Enrichment and analysis of nonenzymatically glycated peptides: boronate affinity chromatography coupled with electron-transfer dissociation mass spectrometry. Journal of Proteome Research. 6: 2323-30. PMID 17488106 DOI: 10.1021/Pr070112Q  0.713
2007 Brock JW, Cotham WE, Thorpe SR, Baynes JW, Ames JM. Detection and identification of arginine modifications on methylglyoxal-modified ribonuclease by mass spectrometric analysis. Journal of Mass Spectrometry : Jms. 42: 89-100. PMID 17143934 DOI: 10.1002/Jms.1144  0.523
2007 Brock JW, Ames JM, Thorpe SR, Baynes JW. Formation of methionine sulfoxide during glycoxidation and lipoxidation of ribonuclease A. Archives of Biochemistry and Biophysics. 457: 170-6. PMID 17141728 DOI: 10.1016/J.Abb.2006.10.029  0.599
2006 Yu Y, Thorpe SR, Jenkins AJ, Shaw JN, Sochaski MA, McGee D, Aston CE, Orchard TJ, Silvers N, Peng YG, McKnight JA, Baynes JW, Lyons TJ. Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes. Diabetologia. 49: 2488-98. PMID 16955213 DOI: 10.1007/S00125-006-0355-8  0.762
2006 Alderson NL, Wang Y, Blatnik M, Frizzell N, Walla MD, Lyons TJ, Alt N, Carson JA, Nagai R, Thorpe SR, Baynes JW. S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate. Archives of Biochemistry and Biophysics. 450: 1-8. PMID 16624247 DOI: 10.1016/J.Abb.2006.03.005  0.775
2005 Brown SM, Smith DM, Alt N, Thorpe SR, Baynes JW. Tissue-specific variation in glycation of proteins in diabetes: evidence for a functional role of amadoriase enzymes. Annals of the New York Academy of Sciences. 1043: 817-23. PMID 16037309 DOI: 10.1196/Annals.1333.094  0.321
2005 Januszewski AS, Jenkins AJ, Baynes JW, Thorpe SR. Lipid-derived modifications of plasma proteins in experimental and human diabetes. Annals of the New York Academy of Sciences. 1043: 404-12. PMID 16037262 DOI: 10.1196/Annals.1333.047  0.337
2005 Meerwaldt R, Links T, Graaff R, Thorpe SR, Baynes JW, Hartog J, Gans R, Smit A. Simple noninvasive measurement of skin autofluorescence. Annals of the New York Academy of Sciences. 1043: 290-8. PMID 16037251 DOI: 10.1196/Annals.1333.036  0.317
2005 Brock JW, Cotham WC, Ames JM, Thorpe SR, Baynes JW. Proteomic method for the quantification of methionine sulfoxide. Annals of the New York Academy of Sciences. 1043: 284-9. PMID 16037250 DOI: 10.1196/Annals.1333.035  0.571
2005 Nagai R, Deemer EK, Brock JW, Thorpe SR, Baynes JW. Effect of glucose concentration on formation of AGEs in erythrocytes in vitro. Annals of the New York Academy of Sciences. 1043: 146-50. PMID 16037233 DOI: 10.1196/Annals.1333.018  0.612
2005 Thomas MC, Baynes JW, Thorpe SR, Cooper ME. The role of AGEs and AGE inhibitors in diabetic cardiovascular disease Current Drug Targets. 6: 453-474. PMID 16026265 DOI: 10.2174/1389450054021873  0.312
2005 Wihler C, Schäfer S, Schmid K, Deemer EK, Münch G, Bleich M, Busch AE, Dingermann T, Somoza V, Baynes JW, Huber J. Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: Effect of angiotensin-converting enzyme and vasopeptidase inhibition Diabetologia. 48: 1645-1653. PMID 16010524 DOI: 10.1007/S00125-005-1837-9  0.323
2005 Januszewski AS, Alderson NL, Jenkins AJ, Thorpe SR, Baynes JW. Chemical modification of proteins during peroxidation of phospholipids. Journal of Lipid Research. 46: 1440-9. PMID 15805546 DOI: 10.1194/Jlr.M400442-Jlr200  0.36
2005 Stroman ML, Metz TO, Thorpe SR, Baynes JW. Cleavage of dicarbonyl compounds by the advanced glycation/lipoxidation end product inhibitor pyridoxamine Annals of the New York Academy of Sciences. 1043: 946. DOI: 10.1196/Annals.1333.160  0.492
2005 Deemer EK, Nagai R, Brock JWC, Thorpe SR, Baynes JW. Effect of glucose concentration on the formation of advanced glycation end products in erythrocytes in Vitro Annals of the New York Academy of Sciences. 1043: 932. DOI: 10.1196/Annals.1333.146  0.48
2004 Cotham WE, Metz TO, Ferguson PL, Brock JW, Hinton DJ, Thorpe SR, Baynes JW, Ames JM. Proteomic analysis of arginine adducts on glyoxal-modified ribonuclease. Molecular & Cellular Proteomics : McP. 3: 1145-53. PMID 15377717 DOI: 10.1074/Mcp.M400002-Mcp200  0.721
2004 Alderson NL, Chachich ME, Frizzell N, Canning P, Metz TO, Januszewski AS, Youssef NN, Stitt AW, Baynes JW, Thorpe SR. Effect of antioxidants and ACE inhibition on chemical modification of proteins and progression of nephropathy in the streptozotocin diabetic rat. Diabetologia. 47: 1385-95. PMID 15309289 DOI: 10.1007/S00125-004-1474-8  0.6
2004 Meerwaldt R, Graaf R, Oomen PHN, Links TP, Jager JJ, Alderson NL, Thorpe SR, Baynes JW, Gans ROB, Smit AJ. Simple non-invasive assessment of advanced glycation endproduct accumulation Diabetologia. 47: 1324-1330. PMID 15243705 DOI: 10.1007/S00125-004-1451-2  0.308
2004 Alt N, Carson JA, Alderson NL, Wang Y, Nagai R, Henle T, Thorpe SR, Baynes JW. Chemical modification of muscle protein in diabetes. Archives of Biochemistry and Biophysics. 425: 200-6. PMID 15111128 DOI: 10.1016/J.Abb.2004.03.012  0.331
2003 Thorpe SR, Baynes JW. Maillard reaction products in tissue proteins: New products and new perspectives Amino Acids. 25: 275-281. PMID 14661090 DOI: 10.1007/s00726-003-0017-9  0.33
2003 Cotham WE, Hinton DJ, Metz TO, Brock JW, Thorpe SR, Baynes JW, Ames JM. Mass spectrometric analysis of glucose-modified ribonuclease. Biochemical Society Transactions. 31: 1426-7. PMID 14641080 DOI: 10.1042/Bst0311426  0.658
2003 Januszewski AS, Alderson NL, Metz TO, Thorpe SR, Baynes JW. Role of lipids in chemical modification of proteins and development of complications in diabetes. Biochemical Society Transactions. 31: 1413-6. PMID 14641077 DOI: 10.1042/Bst0311413  0.603
2003 Baynes JW. Chemical modification of proteins by lipids in diabetes. Clinical Chemistry and Laboratory Medicine. 41: 1159-65. PMID 14598865 DOI: 10.1515/Cclm.2003.179  0.357
2003 Brock JW, Hinton DJ, Cotham WE, Metz TO, Thorpe SR, Baynes JW, Ames JM. Proteomic analysis of the site specificity of glycation and carboxymethylation of ribonuclease. Journal of Proteome Research. 2: 506-13. PMID 14582647 DOI: 10.1021/Pr0340173  0.727
2003 Metz TO, Alderson NL, Thorpe SR, Baynes JW. Pyridoxamine, an inhibitor of advanced glycation and lipoxidation reactions: a novel therapy for treatment of diabetic complications. Archives of Biochemistry and Biophysics. 419: 41-9. PMID 14568007 DOI: 10.1016/J.Abb.2003.08.021  0.608
2003 Metz TO, Alderson NL, Chachich ME, Thorpe SR, Baynes JW. Pyridoxamine traps intermediates in lipid peroxidation reactions in vivo: evidence on the role of lipids in chemical modification of protein and development of diabetic complications. The Journal of Biological Chemistry. 278: 42012-9. PMID 12923193 DOI: 10.1074/Jbc.M304292200  0.621
2003 Gardiner TA, Anderson HR, Degenhardt T, Thorpe SR, Baynes JW, Archer DB, Stitt AW. Prevention of retinal capillary basement membrane thickening in diabetic dogs by a non-steroidal anti-inflammatory drug Diabetologia. 46: 1269-1275. PMID 12861449 DOI: 10.1007/S00125-003-1147-Z  0.301
2003 Alderson NL, Chachich ME, Youssef NN, Beattie RJ, Nachtigal M, Thorpe SR, Baynes JW. The AGE inhibitor pyridoxamine inhibits lipemia and development of renal and vascular disease in Zucker obese rats. Kidney International. 63: 2123-33. PMID 12753299 DOI: 10.1046/J.1523-1755.2003.00027.X  0.305
2003 Yang S, Litchfield JE, Baynes JW. AGE-breakers cleave model compounds, but do not break Maillard crosslinks in skin and tail collagen from diabetic rats. Archives of Biochemistry and Biophysics. 412: 42-6. PMID 12646266 DOI: 10.1016/S0003-9861(03)00015-8  0.351
2002 Sochaski MA, Bartfay WJ, Thorpe SR, Baynes JW, Bartfay E, Lehotay DC, Liu PP. Lipid peroxidation and protein modification in a mouse model of chronic iron overload. Metabolism: Clinical and Experimental. 51: 645-51. PMID 11979400 DOI: 10.1053/Meta.2002.30530  0.737
2002 Degenhardt TP, Alderson NL, Arrington DD, Beattie RJ, Basgen JM, Steffes MW, Thorpe SR, Baynes JW. Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat. Kidney International. 61: 939-50. PMID 11849448 DOI: 10.1046/J.1523-1755.2002.00207.X  0.362
2002 Voziyan PA, Metz TO, Baynes JW, Hudson BG. A post-Amadori inhibitor pyridoxamine also inhibits chemical modification of proteins by scavenging carbonyl intermediates of carbohydrate and lipid degradation. The Journal of Biological Chemistry. 277: 3397-403. PMID 11729198 DOI: 10.1074/Jbc.M109935200  0.616
2001 Sochaski MA, Jenkins AJ, Lyons TJ, Thorpe SR, Baynes JW. Isotope dilution gas chromatography/mass spectrometry method for the determination of methionine sulfoxide in protein. Analytical Chemistry. 73: 4662-7. PMID 11605844 DOI: 10.1021/Ac010228K  0.737
2001 Baynes JW. The role of AGEs in aging: Causation or correlation Experimental Gerontology. 36: 1527-1537. PMID 11525875 DOI: 10.1016/S0531-5565(01)00138-3  0.324
2000 Baynes JW, Thorpe SR. Glycoxidation and lipoxidation in atherogenesis Free Radical Biology and Medicine. 28: 1708-1716. PMID 10946212 DOI: 10.1016/S0891-5849(00)00228-8  0.341
2000 Onorato JM, Jenkins AJ, Thorpe SR, Baynes JW. Pyridoxamine, an inhibitor of advanced glycation reactions, inhibits advanced lipoxidation reactions: Mechanism of action of pyridoxamine Journal of Biological Chemistry. 275: 21177-21184. PMID 10801874 DOI: 10.1074/Jbc.M003263200  0.388
1999 Litchfield JE, Thorpe SR, Baynes JW. Oxygen is not required for the browning and crosslinking of protein by pentoses: Relevance to Maillard reactions in vivo International Journal of Biochemistry and Cell Biology. 31: 1297-1305. PMID 10605822 DOI: 10.1016/S1357-2725(99)00091-6  0.377
1999 Pamplona R, Portero-Otín M, Ruiz C, Bellmunt MJ, Requena JR, Thorpe SR, Baynes JW, Romero M, López-Torres M, Barja G. Thyroid status modulates glycoxidative and lipoxidative modification of tissue proteins Free Radical Biology and Medicine. 27: 901-910. PMID 10515595 DOI: 10.1016/S0891-5849(99)00135-5  0.311
1999 Fountain WC, Requena JR, Jenkins AJ, Lyons TJ, Smyth B, Baynes JW, Thorpe SR. Quantification of N-(glucitol)ethanolamine and N-(carboxymethyl)serine: Two products of nonenzymatic modification of aminophospholipids formed in vivo Analytical Biochemistry. 272: 48-55. PMID 10405292 DOI: 10.1006/Abio.1999.4147  0.331
1999 Degenhardt TP, Fu MX, Voss E, Reiff K, Neidlein R, Strein K, Thorpe SR, Baynes JW, Reiter R. Aminoguanidine inhibits albuminuria, but not the formation of advanced glycation end-products in skin collagen of diabetic rats. Diabetes Research and Clinical Practice. 43: 81-9. PMID 10221660 DOI: 10.1016/S0168-8227(98)00121-1  0.329
1999 Miyata T, Van Ypersele De Strihou C, Kurokawa K, Baynes JW. Alterations in nonenzymatic biochemistry in uremia: Origin and significance of 'carbonyl stress' in long-term uremic complications Kidney International. 55: 389-399. PMID 9987064 DOI: 10.1046/J.1523-1755.1999.00302.X  0.39
1999 Baynes JW, Thorpe SR. Role of oxidative stress in diabetic complications: A new perspective on an old paradigm Diabetes. 48: 1-9. PMID 9892215 DOI: 10.2337/Diabetes.48.1.1  0.339
1998 Onorato JM, Thorpe SR, Baynes JW. Immunohistochemical and ELISA assays for biomarkers of oxidative stress in aging and disease Annals of the New York Academy of Sciences. 854: 277-290. PMID 9928437 DOI: 10.1111/J.1749-6632.1998.Tb09909.X  0.353
1998 Degenhardt TP, Thorpe SR, Baynes JW. Chemical modification of proteins by methylglyoxal Cellular and Molecular Biology (Noisy-Le-Grand, France). 44: 1139-1145. PMID 9846896  0.399
1998 Miyata T, Fu MX, Kurokawa K, Van Ypersele De Strihou C, Thorpe SR, Baynes JW. Autoxidation products of both carbohydrates and lipids are increased in uremic plasma: Is there oxidative stress in uremia? Kidney International. 54: 1290-1295. PMID 9767546 DOI: 10.1046/J.1523-1755.1998.00093.X  0.391
1998 Frye EB, Degenhardt TP, Thorpe SR, Baynes JW. Role of the Maillard reaction in aging of tissue proteins: Advanced glycation end product-dependent increase in imidazolium cross-links in human lens proteins Journal of Biological Chemistry. 273: 18714-18719. PMID 9668043 DOI: 10.1074/Jbc.273.30.18714  0.316
1998 Odani H, Shinzato T, Usami J, Matsumoto Y, Frye EB, Baynes JW, Maeda K. Imidazolium crosslinks derived from reaction of lysine with glyoxal and methylglyoxal are increased in serum proteins of uremic patients: Evidence for increased oxidative stress in uremia Febs Letters. 427: 381-385. PMID 9637262 DOI: 10.1016/S0014-5793(98)00416-5  0.307
1998 Fu S, Fu MX, Baynes JW, Thorpe SR, Dean RT. Presence of dopa and amino acid hydroperoxides in proteins modified with advanced glycation end products (AGEs): Amino acid oxidation products as a possible source of oxidative stress induced by AGE proteins Biochemical Journal. 330: 233-239. PMID 9461515 DOI: 10.1042/Bj3300233  0.335
1997 Degenhardt TP, Grass L, Reddy S, Thorpe SR, Diamandis EP, Baynes JW. Technical note: The serum concentration of the advanced glycation end- product N(ε)-(Carboxymethyl)lysine is increased in uremia Kidney International. 52: 1064-1067. PMID 9328946 DOI: 10.1038/Ki.1997.429  0.303
1997 Wells-Knecht MC, Lyons TJ, McCance DR, Thorpe SR, Baynes JW. Age-dependent increase in ortho-tyrosine and methionine sulfoxide in human skin collagen is not accelerated in diabetes - Evidence against a generalized increase in oxidative stress in diabetes Journal of Clinical Investigation. 100: 839-846. PMID 9259583 DOI: 10.1172/Jci119599  0.348
1997 Requena JR, Ahmed MU, Fountain CW, Degenhardt TP, Reddy S, Perez C, Lyons TJ, Jenkins AJ, Baynes JW, Thorpe SR. Carboxymethylethanolamine, a biomarker of phospholipid modification during the Maillard reaction in vivo Journal of Biological Chemistry. 272: 17473-17479. PMID 9211892 DOI: 10.1074/Jbc.272.28.17473  0.354
1997 Ahmed MU, Brinkmann Frye E, Degenhardt TP, Thorpe SR, Baynes JW. N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins The Biochemical Journal. 324: Pt 2/-. PMID 9182719 DOI: 10.1042/Bj3240565  0.374
1997 Requena JR, Fu MX, Ahmed MU, Jenkins AJ, Lyons TJ, Baynes JW, Thorpe SR. Quantification of malondialdehyde and 4-hydroxynonenal adducts to lysine residues in native and oxidized human low-density lipoprotein The Biochemical Journal. 322: Pt 1/-. PMID 9078279 DOI: 10.1042/Bj3220317  0.301
1997 Requena JR, Fu MX, Ahmed MU, Jenkins AJ, Lyons TJ, Baynes JW, Thorpe SR. Quantification of mallondialdehyde and 4-hydroxynonenal adducts to lysine residues in native and oxidized human low-density lipoprotein Biochemical Journal. 322: 317-325.  0.301
1997 Ahmed MU, Frye EB, Degenhardt TP, Thorpe SR, Baynes JW. N(ε)-(Carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins Biochemical Journal. 324: 565-570.  0.378
1996 Wells-Knecht KJ, Brinkmann E, Wells-Knecht MC, Litchfield JE, Ahmed MU, Reddy S, Zyzak DV, Thorpe SR, Baynes JW. New biomarkers of Maillard reaction damage to proteins Nephrology Dialysis Transplantation. 11: 41-47. PMID 9044306 DOI: 10.1093/Ndt/11.Supp5.41  0.392
1996 Thorpe SR, Baynes JW. Role of the maillard reaction in diabetes mellitus and diseases of aging Drugs and Aging. 9: 69-77. PMID 8820792 DOI: 10.2165/00002512-199609020-00001  0.315
1996 Fu MX, Requena JR, Jenkins AJ, Lyons TJ, Baynes JW, Thorpe SR. The advanced glycation end product, N∈-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions Journal of Biological Chemistry. 271: 9982-9986. PMID 8626637 DOI: 10.1074/Jbc.271.17.9982  0.371
1996 Kornaga T, Zyzak D, Kintinar A, Baynes JW, Thornburg RW. Genetic and biochemical characterization of a "lost" unstable flower color phenotype in interspecific crosses of Nicotiana World Wide Web Journal of Biology. 2: 65-73.  0.576
1995 Baynes JW. Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose Biochemistry®. 34: 3702-3709. PMID 7893666 DOI: 10.1021/Bi00011A027  0.339
1995 Zyzak DV, Richardson JM, Thorpe SR, Baynes JW. Formation of reactive intermediates from Amadori compounds under physiological conditions. Archives of Biochemistry and Biophysics. 316: 547-54. PMID 7840665 DOI: 10.1006/Abbi.1995.1073  0.353
1995 Reddy S, Bichler J, Wells-Knecht KJ, Thorpe SR, Baynes JW. Nε-(carboxymethyl)lysine is a dominant advanced glycation end product (AGE) antigen in tissue proteins Biochemistry. 34: 10872-10878. PMID 7662668 DOI: 10.1021/Bi00034A021  0.342
1995 Wells-Knecht MC, Thorpe SR, Baynes JW. Pathways of formation of glycoxidation products during glycation of collagen Biochemistry. 34: 15134-15141. PMID 7578127 DOI: 10.1021/Bi00046A020  0.307
1994 Fu MX, Wells-Knecht KJ, Blackledge JA, Lyons TJ, Thorpe SR, Baynes JW. Glycation, glycoxidation, and cross-linking of collagen by glucose: Kinetics, mechanisms, and inhibition of late stages of the Maillard reaction Diabetes. 43: 676-683. PMID 8168645 DOI: 10.2337/Diab.43.5.676  0.335
1994 Baker JR, Zyzak DV, Thoroe SR, Baynes JW. Chemistry of the fructosamine assay: D-glucosone is the product of oxidation of Amadori compounds Clinical Chemistry. 40: 1950-1955. PMID 7923778 DOI: 10.1093/Clinchem/40.10.1950  0.306
1993 Dyer DG, Dunn JA, Thorpe SR, Bailie KE, Lyons TJ, McCance DR, Baynes JW. Accumulation of Maillard reaction products in skin collagen in diabetes and aging Journal of Clinical Investigation. 91: 2463-2469. PMID 8514858 DOI: 10.1172/Jci116481  0.352
1993 Baker JR, Zyzak DV, Thorpe SR, Baynes JW. Mechanism of fructosamine assay: Evidence against role of superoxide as intermediate in nitroblue tetrazolium reduction Clinical Chemistry. 39: 2460-2465. PMID 8252716 DOI: 10.1093/Clinchem/39.12.2460  0.313
1991 Baynes JW. Role of oxidative stress in development of complications in diabetes Diabetes. 40: 405-412. PMID 2010041 DOI: 10.2337/Diab.40.4.405  0.359
1991 Lyons TJ, Silvestri G, Dunn JA, Dyer DG, Baynes JW. Role of glycation in modification of lens crystallins in diabetic and nondiabetic senile cataracts Diabetes. 40: 1010-1015. PMID 1907246 DOI: 10.2337/Diab.40.8.1010  0.341
1991 Dyer DG, Blackledge JA, Thorpet SR, Baynes JW. Formation of pentosidine during nonenzymatic browning of proteins by glucose: Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo Journal of Biological Chemistry. 266: 11654-11660. PMID 1904867  0.329
1991 Lyons TJ, Bailie KE, Dyer DG, Dunn JA, Baynes JW. Decrease in skin collagen glycation with improved glycemic control in patients with insulin-dependent diabetes mellitus Journal of Clinical Investigation. 87: 1910-1915. PMID 1904067 DOI: 10.1172/Jci115216  0.362
1991 Knecht KJ, Dunn JA, McFarland KF, McCance DR, Lyons TJ, Thorpe SR, Baynes JW. Effect of diabetes and aging on carboxymethyllysine levels in human urine Diabetes. 40: 190-196. PMID 1899406 DOI: 10.2337/Diab.40.2.190  0.361
1991 Dunn JA, McCance DR, Thorpe SR, Lyons TJ, Baynes JW. Age-dependent accumulation of N(ε)-(carboxymethyl)lysine and N(ε)-(Carboxymethyl)hydroxylysine in human skin collagen Biochemistry. 30: 1205-1210. PMID 1899338 DOI: 10.1021/Bi00219A007  0.343
1991 Dyer DG, Blackledge JA, Katz BM, Hull CJ, Adkisson HD, Thorpe SR, Lyons TJ, Baynes JW. The Maillard reaction in vivo. Zeitschrift Fã¼R Ernã¤Hrungswissenschaft. 30: 29-45. PMID 1858426 DOI: 10.1007/Bf01910730  0.367
1990 Patrick JS, Thorpe SR, Baynes JW. Nonenzymatic glycosylation of protein does not increase with age in normal human lenses Journals of Gerontology. 45: B18-B23. PMID 2295771 DOI: 10.1093/Geronj/45.1.B18  0.328
1990 Dunn JA, Ahmed MU, Murtiashaw MH, Richardson JM, Walla MD, Thorpe SR, Baynes JW. Reaction of ascorbate with lysine and protein under autoxidizing conditions: formation of N epsilon-(carboxymethyl)lysine by reaction between lysine and products of autoxidation of ascorbate. Biochemistry. 29: 10964-70. PMID 2125497 DOI: 10.1021/Bi00501A014  0.322
1989 Baynes JW, Watkins NG, Fisher CI, Hull CJ, Patrick JS, Ahmed MU, Dunn JA, Thorpe SR. The Amadori product on protein: structure and reactions. Progress in Clinical and Biological Research. 304: 43-67. PMID 2675036  0.344
1989 Dunn JA, Patrick JS, Thorpe SR, Baynes JW. Oxidation of glycated proteins: Age-dependent accumulation of Nε-(carboxymethyl)lysine in lens proteins Biochemistry®. 9464-9468. PMID 2514802 DOI: 10.1021/Bi00450A033  0.301
1988 Ahmed MU, Dunn JA, Walla MD, Thorpe SR, Baynes JW. Oxidative degradation of glucose adducts to protein. Formation of 3-(N(ε)-lysino)-lactic acid from model compounds and glycated proteins Journal of Biological Chemistry. 263: 8816-8821. PMID 3132453  0.313
1986 Ahmed MU, Thorpe SR, Baynes JW. Identification of N(ε)-carboxymethyllysine as a degradation product of fructoselysine in glycated protein Journal of Biological Chemistry. 261: 4889-4894. PMID 3082871  0.335
1983 Eble AS, Thorpe SR, Baynes JW. Nonenzymatic glucosylation and glucose-dependent cross-linking of protein Journal of Biological Chemistry. 258: 9406-9412. PMID 6409904  0.304
1980 Thornburg RW, Day JF, Baynes JW, Thorpe SR. Carbohydrate-mediated clearance of immune complexes from the circulation. A role for galactose residues in the hepatic uptake of IgG.antigen complexes Journal of Biological Chemistry. 255: 6820-6825. PMID 7391051  0.607
1979 McFarland KF, Catalano EW, Day JF, Thorpe SR, Baynes JW. Nonenzymatic glucosylation of serum proteins in diabetes mellitus. Diabetes. 28: 1011-1014. PMID 488539 DOI: 10.2337/Diab.28.11.1011  0.331
1974 Hsu AF, Baynes JW, Heath EC. The role of a dolichol-oligosaccharide as an intermediate in glycoprotein biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 71: 2391-5. PMID 4526213 DOI: 10.1073/Pnas.71.6.2391  0.566
1973 Baynes JW, Hsu AF, Heath EC. The role of mannosyl-phosphoryl-dihydropolyisoprenol in the synthesis of mammalian glycoproteins. The Journal of Biological Chemistry. 248: 5693-704. PMID 4723910 DOI: 10.1016/B978-0-12-441550-8.50014-8  0.618
Low-probability matches (unlikely to be authored by this person)
2001 Price DL, Rhett PM, Thorpe SR, Baynes JW. Chelating activity of advanced glycation end-product inhibitors. The Journal of Biological Chemistry. 276: 48967-72. PMID 11677237 DOI: 10.1074/Jbc.M108196200  0.297
1980 Day JF, Ingebretsen CG, Ingebretsen WR, Baynes JW, Thorpe SR. Nonenzymatic glucosylation of serum proteins and hemoglobin: Response to changes in blood glucose levels in diabetic rats Diabetes. 29: 524-527. PMID 6991338 DOI: 10.2337/Diab.29.7.524  0.296
2014 Frizzell N, Baynes JW. Chelation therapy for the management of diabetic complications: a hypothesis and a proposal for clinical laboratory assessment of metal ion homeostasis in plasma. Clinical Chemistry and Laboratory Medicine. 52: 69-75. PMID 23612664 DOI: 10.1515/Cclm-2012-0881  0.295
2005 Waanders F, Greven WL, Baynes JW, Thorpe SR, Kramer AB, Nagai R, Sakata N, van Goor H, Navis G. Renal accumulation of pentosidine in non-diabetic proteinuria-induced renal damage in rats. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 20: 2060-70. PMID 15956058 DOI: 10.1093/Ndt/Gfh939  0.294
2002 Stitt A, Gardiner TA, Alderson NL, Canning P, Frizzell N, Duffy N, Boyle C, Januszewski AS, Chachich M, Baynes JW, Thorpe SR, Anderson NL. The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes. Diabetes. 51: 2826-32. PMID 12196477 DOI: 10.2337/Diabetes.51.9.2826  0.293
2001 Hui YY, McAmis WC, Baynes JW, Schaeffer RC, Wolf MB. Effect of advanced glycation end products on oxidative stress in endothelial cells in culture: A warning on the use of cells studied in serum-free media Diabetologia. 44: 1310-1317. PMID 11692180 DOI: 10.1007/S001250100646  0.292
1989 Daugherty A, Becker NN, Scherrer LA, Sobel BE, Ackerman JJ, Baynes JW, Thorpe SR. Non-invasive detection of protein metabolism in vivo by n.m.r. spectroscopy. Application of a novel 19F-containing residualizing label. The Biochemical Journal. 264: 829-35. PMID 2482736 DOI: 10.1042/Bj2640829  0.289
2005 Fu M, Thorpe SR, Baynes JW. Effects of Aspirin on Glycation, Glycoxidation, and Crosslinking of Collagen Maillard Reactions in Chemistry, Food, and Health. 95-100. DOI: 10.1533/9781845698393.2.95  0.288
1993 Wells-Knecht MC, Huggins TG, Dyer DG, Thorpe SR, Baynes JW. Oxidized amino acids in lens protein with age. Measurement of o-tyrosine and dityrosine in the aging human lens Journal of Biological Chemistry. 268: 12348-12352. PMID 8509374  0.288
2007 Meerwaldt R, Lutgers HL, Links TP, Graaff R, Baynes JW, Gans RO, Smit AJ. Skin autofluorescence is a strong predictor of cardiac mortality in diabetes. Diabetes Care. 30: 107-12. PMID 17192342 DOI: 10.2337/Dc06-1391  0.286
1999 Khalifah RG, Baynes JW, Hudson BG. Breakthroughs and views. Amadorins: Novel post-Amadori inhibitors of advanced glycation reactions Biochemical and Biophysical Research Communications. 257: 251-258. PMID 10198198 DOI: 10.1006/Bbrc.1999.0371  0.285
1983 Murtiashaw MH, Baynes JW, Thorpe SR. Albumin catabolism in diabetic rats Archives of Biochemistry and Biophysics. 225: 256-262. PMID 6614922 DOI: 10.1016/0003-9861(83)90028-0  0.282
2009 Baynes J, Murray DB. Cardiac and Renal Function are Progressively Impaired with Aging in Zucker Diabetic Fatty Type II Diabetic Rats Oxidative Medicine and Cellular Longevity. 2: 328-334. PMID 20716921 DOI: 10.4161/Oxim.2.5.9831  0.28
1984 McFarland KF, Murtiashaw M, Baynes JW. Clinical value of glycosylated serum protein and glycosylated hemoglobin levels in the diagnosis of gestational diabetes mellitus Obstetrics and Gynecology. 64: 516-518. PMID 6483299  0.279
2000 Requena JR, Price DL, Thorpe SR, Baynes JW. Measurement of pentosidine in biological samples. Methods in Molecular Medicine. 38: 209-17. PMID 22351277 DOI: 10.1385/1-59259-070-5:209  0.279
1984 Baynes JW, Thorpe SR, Murtiashaw MH. Nonenzymatic glucosylation of lysine residues in albumin Methods in Enzymology. 88-98. PMID 6436646 DOI: 10.1016/0076-6879(84)06010-9  0.277
1994 Wells-Knecht KJ, Lyons TJ, McCance DR, Thorpe SR, Feather MS, Baynes JW. 3-Deoxyfructose concentrations are increased in human plasma and urine in diabetes Diabetes. 43: 1152-1156. PMID 8070616 DOI: 10.2337/Diab.43.9.1152  0.276
1983 Murtiashaw MH, Young JE, Strickland AL, McFarland KF, Thorpe SR, Baynes JW. Measurement of nonenzymatically glucosylated serum protein by an improved thiobarbituric acid assay Clinica Chimica Acta. 130: 177-187. PMID 6872256 DOI: 10.1016/0009-8981(83)90115-8  0.276
2004 Ediger MN, Hull EL, Unione AHT, Deemer EK, Stroman ML, Baynes JW. Use of fluorescence and near-infrared spectroscopies for noninvasive measurement of skin-collagen Advanced Glycation Endproducts: a feasibility study Biosilico. DOI: 10.1364/Bio.2004.Wc2  0.274
2005 Zyzak DV, Wells-Knecht KJ, Blackledge JA, Litchfield JE, Wells-Knecht MC, Fu M, Thorpe SR, Feather MS, Baynes JW. Pathways of the Maillard Reaction In Vitro and In Vivo Maillard Reactions in Chemistry, Food, and Health. 274-280. DOI: 10.1533/9781845698393.4.274  0.273
1987 Watkins NG, Neglia-Fisher CI, Dyer DG, Thorpe SR, Baynes JW. Effect of phosphate on the kinetics and specificity of glycation of protein Journal of Biological Chemistry. 262: 7207-7212. PMID 3584112  0.272
2005 Meerwaldt R, Hartog JW, Graaff R, Huisman RJ, Links TP, den Hollander NC, Thorpe SR, Baynes JW, Navis G, Gans RO, Smit AJ. Skin autofluorescence, a measure of cumulative metabolic stress and advanced glycation end products, predicts mortality in hemodialysis patients. Journal of the American Society of Nephrology : Jasn. 16: 3687-93. PMID 16280473 DOI: 10.1681/Asn.2005020144  0.27
1995 Cefalu WT, Bell-Farrow AD, Wang ZQ, Sonntag WE, Fu MX, Baynes JW, Thorpe SR. Caloric restriction decreases age-dependent accumulation of the glycoxidation products, N epsilon-(carboxymethyl)lysine and pentosidine, in rat skin collagen. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 50: B337-41. PMID 7583789 DOI: 10.1093/Gerona/50A.6.B337  0.27
2004 Hull EL, Ediger MN, Unione AHT, Deemer EK, Stroman ML, Baynes JW. Noninvasive, optical detection of diabetes: Model studies with porcine skin Optics Express. 12: 4496-4510. DOI: 10.1364/Opex.12.004496  0.265
1987 Lyons TJ, Klein RL, Baynes JW, Stevenson HC, Lopes-Virella MF. Stimulation of cholesteryl ester synthesis in human monocyte-derived macrophages by low-density lipoproteins from type 1 (insulin-dependent) diabetic patients: the influence of non-enzymatic glycosylation of low-density lipoproteins. Diabetologia. 30: 916-23. PMID 3436488 DOI: 10.1007/Bf00295874  0.265
1996 Baynes JW, Thorpe SR. The role of oxidative stress in diabetic complications Current Opinion in Endocrinology and Diabetes. 3: 277-284. DOI: 10.1097/00060793-199608000-00001  0.264
1995 Lal S, Szwergold BS, Taylor AH, Randall WC, Kappler F, Wells-Knecht K, Baynes JW, Brown TR. Metabolism of fructose-3-phosphate in the diabetic rat lens. Archives of Biochemistry and Biophysics. 318: 191-9. PMID 7726561 DOI: 10.1006/Abbi.1995.1220  0.264
1986 Lyons TJ, Baynes JW, Patrick JS, Colwell JA, Lopes-Virella MF. Glycosylation of low density lipoprotein in patients with Type I (insulin-dependent) diabetes: Correlations with other parameters of glycaemic control Diabetologia. 29: 685-689. PMID 3803742 DOI: 10.1007/Bf00870276  0.261
1988 Maxwell JL, Baynes JW, Thorpe SR. Inulin-125I-tyramine, an improved residualizing label for studies on sites of catabolism of circulating proteins. The Journal of Biological Chemistry. 263: 14122-7. PMID 2459117  0.261
1992 Fu MX, Knecht KJ, Thorpe SR, Baynes JW. Role of oxygen in cross-linking and chemical modification of collagen by glucose Diabetes. 41: 42-48. PMID 1526335 DOI: 10.2337/Diab.41.2.S42  0.261
1979 Guthrow CE, Morris MA, Day JF, Thorpe SR, Baynes JW. Enhanced nonenzymatic glucosylation of human serum albumin in diabetes mellitus Proceedings of the National Academy of Sciences of the United States of America. 76: 4258-4261. PMID 291961 DOI: 10.1073/Pnas.76.9.4258  0.257
2000 Baynes JW. From life to death - The struggle between chemistry and biology during aging: The Maillard reaction as an amplifier of genomic damage Biogerontology. 1: 235-246. PMID 11707900 DOI: 10.1023/A:1010034213093  0.257
2005 Klein RL, Semler AJ, Baynes JW, Thorpe SR, Lyons TJ, Jenkins AJ. Glycation does not alter LDL-induced secretion of tissue plasminogen activator and plasminogen activator inhibitor-1 from human aortic endothelial cells. Annals of the New York Academy of Sciences. 1043: 379-89. PMID 16037259 DOI: 10.1196/Annals.1333.044  0.257
2004 Baynes JW. The clinical chemome: a tool for the diagnosis and management of chronic disease. Clinical Chemistry. 50: 1116-7. PMID 15229147 DOI: 10.1373/Clinchem.2004.034645  0.254
2002 Baynes JW. The Maillard hypothesis on aging: time to focus on DNA. Annals of the New York Academy of Sciences. 959: 360-7. PMID 11976210 DOI: 10.1111/J.1749-6632.2002.Tb02107.X  0.254
1986 Strobel JL, Cady SG, Borg TK, Terracio L, Baynes JW, Thorpe SR. Identification of fibroblasts as a major site of albumin catabolism in peripheral tissues. The Journal of Biological Chemistry. 261: 7989-94. PMID 3519616  0.254
2007 den Hollander NC, Mulder DJ, Graaff R, Thorpe SR, Baynes JW, Smit GP, Smit AJ. Advanced glycation end products and the absence of premature atherosclerosis in glycogen storage disease Ia. Journal of Inherited Metabolic Disease. 30: 916-23. PMID 17570077 DOI: 10.1007/S10545-007-0507-0  0.253
1993 Huggins TG, Wells-Knecht MC, Detorie NA, Baynes JW, Thorpe SR. Formation of o-tyrosine and dityrosine in proteins during radiolytic and metal-catalyzed oxidation Journal of Biological Chemistry. 268: 12341-12347. PMID 8509373  0.253
1984 Strickland AL, McFarland KF, Murtiashaw MH, Thorpe SR, Baynes JW. Changes in blood protein glycosylation during a diabetes summer camp Diabetes Care. 7: 183-185. PMID 6734384 DOI: 10.2337/Diacare.7.2.183  0.252
2005 Berry GT, Baynes JW, Wells-Knecht KJ, Szwergold BS, Santer R. Elements of diabetic nephropathy in a patient with GLUT 2 deficiency. Molecular Genetics and Metabolism. 86: 473-7. PMID 16288895 DOI: 10.1016/J.Ymgme.2005.09.010  0.249
2005 Meerwaldt R, Links TP, Graaff R, Hoogenberg K, Lefrandt JD, Baynes JW, Gans ROB, Smit AJ. Increased accumulation of skin advanced glycation end-products precedes and correlates with clinical manifestation of diabetic neuropathy Diabetologia. 48: 1637-1644. PMID 16021416 DOI: 10.1007/S00125-005-1828-X  0.249
2007 Baynes JW. Dietary ALEs are a risk to human health--NOT! Molecular Nutrition & Food Research. 51: 1102-6. PMID 17854007 DOI: 10.1002/Mnfr.200600287  0.246
1985 Strobel JL, Baynes JW, Thorpe SR. 125I-glycoconjugate labels for identifying sites of protein catabolism in vivo: Effect of structure and chemistry of coupling to protein on label entrapment in cells after protein degradation Archives of Biochemistry and Biophysics. 240: 635-645. PMID 2411222 DOI: 10.1016/0003-9861(85)90071-2  0.241
1995 Chroneos ZC, Baynes JW, Thorpe SR. Identification of liver endothelial cells as the primary site of IgM catabolism in the rat Archives of Biochemistry and Biophysics. 319: 63-73. PMID 7771806 DOI: 10.1006/Abbi.1995.1267  0.239
1993 McCance DR, Dyer DG, Dunn JA, Bailie KE, Thorpe SR, Baynes JW, Lyons TJ. Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus Journal of Clinical Investigation. 91: 2470-2478. PMID 8514859 DOI: 10.1172/Jci116482  0.239
2005 Degenhardt TP, Brinkmann-Frye E, Thorpe SR, Baynes JW. Role of Carbonyl Stress in Aging and Age-Related Diseases The Maillard Reaction in Foods and Medicine. 3-10. DOI: 10.1533/9781845698447.1.3  0.237
2011 Bardella C, El-Bahrawy M, Frizzell N, Adam J, Ternette N, Hatipoglu E, Howarth K, O'Flaherty L, Roberts I, Turner G, Taylor J, Giaslakiotis K, Macaulay VM, Harris AL, Chandra A, ... ... Baynes JW, et al. Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status. The Journal of Pathology. 225: 4-11. PMID 21630274 DOI: 10.1002/Path.2932  0.235
2009 MacDonald JA, Degenhardt T, Baynes JW, Storey KB. Glycation of wood frog (Rana sylvatica) hemoglobin and blood proteins: in vivo and in vitro studies. Cryobiology. 59: 223-5. PMID 19540217 DOI: 10.1016/J.Cryobiol.2009.06.008  0.234
2004 Smith ZJ, Berger AJ, Hull EL, Ediger MN, Baynes JW. In Vitro Quantitation of Advanced Glycation Endproducts in Porcine Dermis using Raman Spectroscopy Frontiers in Optics. DOI: 10.1364/Fio.2004.Ftug47  0.232
1988 Baynes JW, Maxwell JL, Rahman KM, Thorpe SR. Purification of residualizing glycoconjugate labels for protein by reversed-phase high-pressure liquid chromatography. Analytical Biochemistry. 170: 382-6. PMID 3394935 DOI: 10.1016/0003-2697(88)90647-1  0.229
1985 Neglia CL, Cohen HJ, Garber AR, Thorpe SR, Baynes JW. Characterization of glycated proteins by 13C NMR spectroscopy. Identification of specific sites of protein modification by glucose Journal of Biological Chemistry. 260: 5406-5410. PMID 2985592  0.229
1990 Lucas KL, Baynes JW, Thorpe SR. Intracellular processing of residualizing labels in different cell types in vitro. Journal of Cellular Physiology. 142: 581-5. PMID 1690215 DOI: 10.1002/Jcp.1041420318  0.226
1993 Thorpe SR, Baynes JW, Chroneos ZC. The design and application of residualizing labels for studies of protein catabolism Faseb Journal. 7: 399-405. PMID 8462781 DOI: 10.1096/Fasebj.7.5.8462781  0.222
2006 Sweitzer SM, Fann SA, Borg TK, Baynes JW, Yost MJ. What is the future of diabetic wound care? Diabetes Educator. 32: 197-210. PMID 16554422 DOI: 10.1177/0145721706286897  0.221
1981 Baynes JW, Thorpe SR. Identification of the sites of albumin catabolism in the rat Archives of Biochemistry and Biophysics. 206: 372-379. PMID 7224645 DOI: 10.1016/0003-9861(81)90104-1  0.219
1994 Thorpe SR, Baynes JW. Residualizing glycoconjugates: Biologically inert tracers for studies on protein endocytosis and catabolism Methods in Enzymology. 242: 3-17. PMID 7891587 DOI: 10.1016/0076-6879(94)42003-3  0.218
2000 Verzijl N, DeGroot J, Oldehinkel E, Bank RA, Thorpe SR, Baynes JW, Bayliss MT, Bijlsma JWJ, Lafeber FPJG, TeKoppele JM. Age-related accumulation of Maillard reaction products in human articular cartilage collagen Biochemical Journal. 350: 381-387. PMID 10947951 DOI: 10.1042/Bj3500381  0.217
2009 Baynes JW, Murray DB. The metal chelators, trientine and citrate, inhibit the development of cardiac pathology in the Zucker diabetic rat. Experimental Diabetes Research. 2009: 696378. PMID 19390595 DOI: 10.1155/2009/696378  0.215
1983 Neglia CI, Cohen HJ, Garber AR, Ellis PD, Thorpe SR, Baynes JW. 13C NMR investigation of nonenzymatic glucosylation of protein. Model studies using RNase A. The Journal of Biological Chemistry. 258: 14279-83. PMID 6643480  0.211
1982 Henderson LA, Baynes JW, Thorpe SR. Identification of the sites of IgG catabolism in the rat Archives of Biochemistry and Biophysics. 215: 1-11. PMID 7092219 DOI: 10.1016/0003-9861(82)90272-7  0.21
2000 Dominguez JH, Tang N, Xu W, Evan AP, Siakotos AN, Agarwal R, Walsh J, Deeg M, Pratt JH, March KL, Monnier VM, Weiss MF, Baynes JW, Peterson R. Studies of renal injury III: Lipid-induced nephropathy in type II diabetes Kidney International. 57: 92-104. PMID 10620191 DOI: 10.1046/J.1523-1755.2000.00814.X  0.209
2009 Zhang Y, Ikeno Y, Qi W, Chaudhuri A, Li Y, Bokov A, Thorpe SR, Baynes JW, Epstein C, Richardson A, Van Remmen H. Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 1212-20. PMID 19776219 DOI: 10.1093/Gerona/Glp132  0.209
1990 Maxwell JL, Terracio L, Borg TK, Baynes JW, Thorpe SR. A fluorescent residualizing label for studies on protein uptake and catabolism in vivo and in vitro. The Biochemical Journal. 267: 155-62. PMID 1691636 DOI: 10.1042/Bj2670155  0.208
2005 Somoza V, Lindenmeier M, Hofmann T, Frank O, Erbersdobler HF, Baynes JW, Thorpe SR, Heidland A, Zill H, Bek S, Huber J, Weigle T, Scheidler S, Busch AE, Sebeková K. Dietary bread crust advanced glycation end products bind to the receptor for AGEs in HEK-293 kidney cells but are rapidly excreted after oral administration to healthy and subtotally nephrectomized rats. Annals of the New York Academy of Sciences. 1043: 492-500. PMID 16037271 DOI: 10.1196/Annals.1333.056  0.203
2002 Verzijl N, DeGroot J, Ben ZC, Brau-Benjamin O, Maroudas A, Bank RA, Mizrahi J, Schalkwijk CG, Thorpe SR, Baynes JW, Bijlsma JW, Lafeber FP, TeKoppele JM. Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis. Arthritis and Rheumatism. 46: 114-23. PMID 11822407 DOI: 10.1002/1529-0131(200201)46:1<114::Aid-Art10025>3.0.Co;2-P  0.202
1993 Bichler J, Baynes JW, Thorpe SR. Catabolism of hirudin and thrombin-hirudin complexes in the rat Biochemical Journal. 296: 771-776. PMID 8280076 DOI: 10.1042/Bj2960771  0.195
1995 Brinkmann E, Wells-Knecht KJ, Thorpe SR, Baynes JW. Characterization of an imidazolium compound formed by reaction of methylglyoxal and Nα-hippuryllysine Journal of the Chemical Society, Perkin Transactions 1. 91: 2817-2818. DOI: 10.1039/P19950002817  0.189
2000 Verzijl N, DeGroot J, Thorpe SR, Bank RA, Shaw JN, Lyons TJ, Bijlsma JWJ, Lafeber FPJG, Baynes JW, TeKoppele JM. Effect of collagen turnover on the accumulation of advanced glycation end products Journal of Biological Chemistry. 275: 39027-39031. PMID 10976109 DOI: 10.1074/Jbc.M006700200  0.189
2013 Lima M, Sato S, Enos RT, Baynes JW, Carson JA. Development of an UPLC mass spectrometry method for measurement of myofibrillar protein synthesis: application to analysis of murine muscles during cancer cachexia. Journal of Applied Physiology (Bethesda, Md. : 1985). 114: 824-8. PMID 23329823 DOI: 10.1152/Japplphysiol.01141.2012  0.178
2003 McAmis WC, Schaeffer RC, Baynes JW, Wolf MB. Menadione causes endothelial barrier failure by a direct effect on intracellular thiols, independent of reactive oxidant production. Biochimica Et Biophysica Acta. 1641: 43-53. PMID 12788228 DOI: 10.1016/S0167-4889(03)00063-6  0.178
1993 Blackledge JA, Fu MX, Thorpe SR, Baynes JW. Characterization of a triazine (2-[(3-amino-1,2,4-triazin-5-yl)methylene]-hydrazinecarboximideamide) formed from glucose and aminoguanidine under oxidative conditions Journal of Organic Chemistry. 58: 2001-2002. DOI: 10.1021/Jo00060A008  0.174
2002 de Grey AD, Baynes JW, Berd D, Heward CB, Pawelec G, Stock G. Is human aging still mysterious enough to be left only to scientists? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 24: 667-76. PMID 12111727 DOI: 10.1002/Bies.10113  0.173
2006 Wolf MB, Baynes JW. The anti-cancer drug, doxorubicin, causes oxidant stress-induced endothelial dysfunction. Biochimica Et Biophysica Acta. 1760: 267-71. PMID 16337743 DOI: 10.1016/J.Bbagen.2005.10.012  0.17
1992 Knecht KJ, Feather MS, Baynes JW. Detection of 3-deoxyfructose and 3-deoxyglucosone in human urine and plasma: Evidence for intermediate stages of the maillard reaction in vivo Archives of Biochemistry and Biophysics. 294: 130-137. PMID 1550339 DOI: 10.1016/0003-9861(92)90146-N  0.165
2008 Morcos M, Du X, Pfisterer F, Hutter H, Sayed AA, Thornalley P, Ahmed N, Baynes J, Thorpe S, Kukudov G, Schlotterer A, Bozorgmehr F, El Baki RA, Stern D, Moehrlen F, et al. Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans. Aging Cell. 7: 260-9. PMID 18221415 DOI: 10.1111/J.1474-9726.2008.00371.X  0.159
2011 White JP, Baynes JW, Welle SL, Kostek MC, Matesic LE, Sato S, Carson JA. The regulation of skeletal muscle protein turnover during the progression of cancer cachexia in the Apc(Min/+) mouse. Plos One. 6: e24650. PMID 21949739 DOI: 10.1371/Journal.Pone.0024650  0.158
1999 Jahn M, Baynes JW, Spiteller G. The reaction of hyaluronic acid and its monomers, glucuronic acid and N- acetylglucosamine, with reactive oxygen species Carbohydrate Research. 321: 228-234. PMID 10614067 DOI: 10.1016/S0008-6215(99)00186-X  0.156
1999 Jenkins AJ, Li W, Moller K, Klein RL, Fu MX, Baynes JW, Thorpe SR, Lyons TJ. Pre-enrichment of modified low density lipoproteins with α-tocopherol mitigates adverse effects on cultured retinal capillary cells Current Eye Research. 19: 137-145. PMID 10420183 DOI: 10.1076/ceyr.19.2.137.5329  0.148
2011 White JP, Baltgalvis KA, Puppa MJ, Sato S, Baynes JW, Carson JA. Muscle oxidative capacity during IL-6-dependent cancer cachexia. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 300: R201-11. PMID 21148472 DOI: 10.1152/Ajpregu.00300.2010  0.14
2003 Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, Alderson NL, Baynes JW, Epstein CJ, Huang TT, Nelson J, Strong R, Richardson A. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiological Genomics. 16: 29-37. PMID 14679299 DOI: 10.1152/Physiolgenomics.00122.2003  0.139
2007 Wolf MB, Baynes JW. Cadmium and mercury cause an oxidative stress-induced endothelial dysfunction. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 20: 73-81. PMID 16752219 DOI: 10.1007/S10534-006-9016-0  0.136
1978 Brown TL, Henderson LA, Thorpe SR, Baynes JW. The effect of α-mannose-terminal oligosaccharides on the survival of glycoproteins in the circulation. Rapid uptake and catabolism of bovine pancreatic ribonuclease B by nonparenchymal cells of rat liver Archives of Biochemistry and Biophysics. 188: 418-428. PMID 677907 DOI: 10.1016/S0003-9861(78)80026-5  0.133
2005 Sebeková K, Hofmann T, Boor P, Sebeková K, Ulicná O, Erbersdobler HF, Baynes JW, Thorpe SR, Heidland A, Somoza V. Renal effects of oral maillard reaction product load in the form of bread crusts in healthy and subtotally nephrectomized rats. Annals of the New York Academy of Sciences. 1043: 482-91. PMID 16037270 DOI: 10.1196/Annals.1333.055  0.132
1981 Morrone S, Pentchev PG, Baynes JW, Thorpe SR. Studies in Vivo of the Tissue Uptake, Cellular Distribution and Catabolic Turnover of Exogenous Glucocerebrosidase in Rat Biochemical Journal. 194: 733-742. PMID 7306020 DOI: 10.1042/Bj1940733  0.129
1983 Murtiashaw MH, Thorpe SR, Baynes JW. Determination of the specific activity of NaB3H4 Analytical Biochemistry. 135: 443-446. PMID 6660518 DOI: 10.1016/0003-2697(83)90709-1  0.127
1983 Rush JS, Thorpe SR, Baynes JW. A rapid micro-modification of the quantitative immunoprecipitation assay. Journal of Immunological Methods. 62: 247-55. PMID 6886434 DOI: 10.1016/0022-1759(83)90252-1  0.122
2012 White JP, Puppa MJ, Sato S, Gao S, Price RL, Baynes JW, Kostek MC, Matesic LE, Carson JA. IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the ApcMin/+ mouse. Skeletal Muscle. 2: 14. PMID 22769563 DOI: 10.1186/2044-5040-2-14  0.12
2011 Puppa MJ, White JP, Sato S, Cairns M, Baynes JW, Carson JA. Gut barrier dysfunction in the Apc(Min/+) mouse model of colon cancer cachexia. Biochimica Et Biophysica Acta. 1812: 1601-6. PMID 21914473 DOI: 10.1016/J.Bbadis.2011.08.010  0.12
2014 Baynes JW, Gillery P. Frontiers in research on the Maillard reaction in aging and chronic disease. Clinical Chemistry and Laboratory Medicine. 52: 1-3. PMID 23940060 DOI: 10.1515/Cclm-2013-0551  0.12
2013 Frizzell N, Baynes JW. Chelation therapy: overlooked in the treatment and prevention of diabetes complications? Future Medicinal Chemistry. 5: 1075-8. PMID 23795964 DOI: 10.4155/Fmc.13.73  0.12
2011 Frizzell N, Thomas Sa, Baynes JW. (2-succinyl)-cysteine (2SC): a Biomarker of Mitochondrial Stress in Type 2 Diabetes Free Radical Biology and Medicine. 51. DOI: 10.1016/J.Freeradbiomed.2011.10.159  0.12
2010 White J, Puppa M, Valazquez K, Sato S, Baynes J, Welle S, Carson J. Skeletal Muscle Protein Synthesis and IL-6 induced Cancer Cachexia. Medicine and Science in Sports and Exercise. 42: 76. DOI: 10.1249/01.Mss.0000389403.35332.14  0.12
2010 White JP, Puppa MJ, Velazquez KT, Baynes JW, Carson JA. Treadmill Exercise And IL-6-induced Cachexia In The ApcMin/+ Mouse: 1710 Medicine and Science in Sports and Exercise. 42: 372. DOI: 10.1249/01.Mss.0000384667.30632.Ab  0.12
2010 Puppa MJ, White JP, Velazquez KT, Baynes JW, Carson JA. Treadmill Exercise And Glucose Clearance In ApcMin/+ Mice: 1573 Medicine and Science in Sports and Exercise. 42: 322. DOI: 10.1249/01.Mss.0000384565.19849.48  0.12
2010 Frizzell N, Baynes JW. Modification of Cysteine Residues in Protein by Endogenous Oxidants and Electrophiles Endogenous Toxins: Targets For Disease Treatment and Prevention. 43-63. DOI: 10.1002/9783527628100.ch2  0.12
2008 McClellan JL, Baltgalvis KA, White JP, Cairns MA, Baynes JW, Carson JA. The Effect of Pyridoxamine Administration on Cachexia in ApcMin/+ Mice: 1958 Medicine and Science in Sports and Exercise. 40. DOI: 10.1249/01.Mss.0000323370.54472.04  0.12
2007 Morcos M, Du X, Sayed A, Hutter H, Pfisterer F, Kukudov G, Thornalley P, Baynes J, Thorpe S, Baki RAE, Rabbani N. Life extension in Caenorhabditis elegans by overexpression of Glyoxalase I — A mechanistic integration of protein damage by glycation, oxidation and nitratio Comparative Biochemistry and Physiology a-Molecular & Integrative Physiology. 146. DOI: 10.1016/J.Cbpa.2007.01.050  0.12
2005 Requena JR, Ahmed MU, Reddy S, Fountain CW, Degenhardt TP, Baynes JW, Thorpe SR. Detection of Age-Lipids in Vivo: Carboxymethylation of Aminophospholipids in LDL and Red Cell Membranes The Maillard Reaction in Foods and Medicine. 439. DOI: 10.1533/9781845698447.8.439A  0.12
2005 Wells-Knecht MC, Fu M, Thorpe SR, Baynes JW. Effect of Glucose and Glycation on Protein Oxidation Maillard Reactions in Chemistry, Food, and Health. 427. DOI: 10.1533/9781845698393.7.427A  0.12
2005 Baynes JW, Monnier VM, Ames JM, Thorpe SR. Preface Annals of the New York Academy of Sciences. 1043: xix-xx. DOI: 10.1196/annals.1333.165  0.12
2005 Brown SM, Smith DM, Thorpe SR, Baynes JW. Evidence for variations in deglycating activity among tissues in the diabetic rat Annals of the New York Academy of Sciences. 1043: 939. DOI: 10.1196/Annals.1333.153  0.12
2005 Meerwaldt R, Graaff R, Links TP, Baynes JW, Navis GJ, Huisman RM, Gans ROB, Smit AJ. Skin autofluorescence, a noninvasive measure of advanced glycation end product accumulation, is a predictor of mortality in hemodialysis patients Annals of the New York Academy of Sciences. 1043: 911. DOI: 10.1196/Annals.1333.125  0.12
2003 Dominiczak MH, Baynes JW. Editors' Introduction: Welcome to the Special Issue on Diabetes Mellitus Clinical Chemistry and Laboratory Medicine. 41: 1103-1103. DOI: 10.1515/Cclm.2003.171  0.12
2002 Shaw JN, Baynes JW, Thorpe SR. N epsilon-(carboxymethyl)lysine (CML) as a biomarker of oxidative stress in long-lived tissue proteins. Methods in Molecular Biology (Clifton, N.J.). 186: 129-37. PMID 12013760 DOI: 10.1385/1-59259-173-6:129  0.12
1999 Baynes JW. Structure-based Ligand Design. Klaus Gubernator and Hans-J. Böhm, editors (Methods and Principles in Medicinal Chemistry, vol. 6.) Clinical Chemistry and Laboratory Medicine. 37. DOI: 10.1515/Cclm.1999.37.7.772  0.12
1995 Wells-Knecht KJ, Brinkmann E, Baynes JW. Characterization of an Imidazolium Salt Formed from Glyoxal and N.alpha.-Hippuryllysine: A Model for Maillard Reaction Crosslinks in Proteins Journal of Organic Chemistry. 60: 6246-6247. DOI: 10.1021/Jo00125A001  0.12
1995 Wells-Knecht KJ, Brinkmann E, Baynes JW. Characterization of an imidazolium salt formed from glyoxal and Nα-hippuryllysine: A model for maillard reaction crosslinks in proteins Journal of Organic Chemistry. 60: 6246-6247.  0.12
1994 Baynes JW. AGEing growth factors: A role in diabetic vascular disease? Journal of Clinical Investigation. 94: 2. PMID 8040261 DOI: 10.1172/Jci117307  0.12
1993 Wells-Knecht MC, Dunn JA, Dyer DG, Fu M, Wells-Knecht KJ, Lyons TJ, McCance DR, Thorpe SR, Baynes JW. Oxidation and glycoxidation of protein in diabetes and aging Free Radical Biology and Medicine. 15: 485. DOI: 10.1016/0891-5849(93)90239-Q  0.12
1992 Huggins TG, Staton MW, Dyer DG, Detorie NJ, Walla MD, Baynes JW, Thorpe SR. o-Tyrosine and dityrosine concentrations in oxidized proteins and lens proteins with age Annals of the New York Academy of Sciences. 663: 436-437. PMID 1482077 DOI: 10.1111/J.1749-6632.1992.Tb38692.X  0.12
1992 Dowd MM, Baynes JW, Thorpe SR. Synthesis of N,N-dilactitol ethylenediamine: A versatile spacer for attachment of residualizing labels to protein Analytical Biochemistry. 205: 369-371. PMID 1443586 DOI: 10.1016/0003-2697(92)90451-C  0.12
1990 Walsh CH, Murphy AL, Cunningham S, McKenna TJ, Byrne B, Igoe D, Cunningham SK, Culliton M, Costigan C, McKnight JA, McCance DR, Roberts G, Sheridan B, Atkinson AB, Lanigan O, ... ... Baynes JW, et al. Irish endocrine society - Proceedings of the Irish Endocrine Society, 14th annual meeting, Cork Regional Hospital, Cork, November 3rd'4th, 1989 Irish Journal of Medical Science. 159: 123-127. DOI: 10.1007/BF02937446  0.12
1985 Watkins NG, Thorpe SR, Baynes JW. Glycation of the amino groups in protein: Studies on the specificity of modification of RNase by glucose Journal of Biological Chemistry. 260: 10629-10636. PMID 4030761  0.12
1985 Ahmed MU, Thorpe SR, Baynes JW. Identification of N(ε)-carboxymethylysine, a modified amino acid formed by decomposition of fructoselysine in glycated proteins Federation Proceedings. 44: No. 7082.  0.12
1984 Baynes JW, Bunn HF, Goldstein D, Harris M, Martin DB, Peterson C, Winterhalter K. National Diabetes Data Group: report of the expert committee on glucosylated hemoglobin. Diabetes Care. 7: 602-6. PMID 6510184 DOI: 10.2337/diacare.7.6.602  0.12
1984 Kennedy L, Baynes JW. Non-enzymatic glycosylation and the chronic complications of diabetes: an overview Diabetologia. 26: 93-98. PMID 6370764 DOI: 10.1007/Bf00281113  0.12
1984 Strobel JL, Baynes JW, Thorpe SR. Lactitol-125I-tyrosine: Synthesis and coupling to protein for metabolic studies Federation Proceedings. 43: no. 3522.  0.12
1984 Watkins NG, Thorpe SR, Baynes JW. Nonenzymatic glucosylation of ribonuclease: Effect of phosphate on sites of modification Federation Proceedings. 43: no. 1671.  0.12
1984 Neglia CI, Thorpe SR, Baynes JW. 13C NMR characterization of nonenzymatically glucosylated proteins Federation Proceedings. 43: no. 1672.  0.12
1981 Baynes JW, Van Zile J, Henderson LA, Thorpe SR. In vivo sites of uptake of short- and long-lived circulating proteins: Clearance of protein in peripheral tissue Birth Defects: Original Article Series. 17: 103-113.  0.12
1993 Potter D, Chroneos ZC, Baynes JW, Sinclair PR, Gorman N, Liem HH, Muller-Eberhard U, Thorpe SR. In vivo fate of hemopexin and heme-hemopexin complexes in the rat Archives of Biochemistry and Biophysics. 300: 98-104. PMID 8424694 DOI: 10.1006/Abbi.1993.1014  0.11
2012 Puppa MJ, White JP, Velázquez KT, Baltgalvis KA, Sato S, Baynes JW, Carson JA. The effect of exercise on IL-6-induced cachexia in the Apc ( Min/+) mouse. Journal of Cachexia, Sarcopenia and Muscle. 3: 117-37. PMID 22476915 DOI: 10.1007/S13539-011-0047-1  0.097
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