Johan Jakobsson - Publications

Affiliations: 
Wallenberg Neuroscience Center, Lund University, Lund, Skåne län, Sweden 

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Garza R, Sharma Y, Atacho DAM, Thiruvalluvan A, Abu Hamdeh S, Jönsson ME, Horvath V, Adami A, Ingelsson M, Jern P, Hammell MG, Englund E, Kirkeby A, Jakobsson J, Marklund N. Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia. Cell Reports. 42: 113395. PMID 37967557 DOI: 10.1016/j.celrep.2023.113395  0.774
2023 Garza R, Atacho DAM, Adami A, Gerdes P, Vinod M, Hsieh P, Karlsson O, Horvath V, Johansson PA, Pandiloski N, Matas-Fuentes J, Quaegebeur A, Kouli A, Sharma Y, Jönsson ME, ... ... Jakobsson J, et al. LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification. Science Advances. 9: eadh9543. PMID 37910626 DOI: 10.1126/sciadv.adh9543  0.793
2022 Drouin-Ouellet J, Legault EM, Nilsson F, Pircs K, Bouquety J, Petit F, Shrigley S, Birtele M, Pereira M, Storm P, Sharma Y, Bruzelius A, Vuono R, Kele M, Stoker TB, ... ... Jakobsson J, et al. Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson's disease. Stem Cell Reports. PMID 36150382 DOI: 10.1016/j.stemcr.2022.08.010  0.525
2022 Johansson PA, Adami A, Jakobsson J. CRISPRi-mediated transcriptional silencing in iPSCs for the study of human brain development. Star Protocols. 3: 101285. PMID 35496780 DOI: 10.1016/j.xpro.2022.101285  0.307
2021 Pircs K, Drouin-Ouellet J, Horváth V, Gil J, Rezeli M, Garza R, Grassi DA, Sharma Y, St-Amour I, Harris K, Jönsson ME, Johansson PA, Vuono R, Fazal SV, Stoker T, ... ... Jakobsson J, et al. Distinct subcellular autophagy impairments in induced neurons from Huntington's disease patients. Brain : a Journal of Neurology. PMID 34936701 DOI: 10.1093/brain/awab473  0.796
2021 Johansson PA, Brattås PL, Douse CH, Hsieh P, Adami A, Pontis J, Grassi D, Garza R, Sozzi E, Cataldo R, Jönsson ME, Atacho DAM, Pircs K, Eren F, Sharma Y, ... ... Jakobsson J, et al. A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development. Cell Stem Cell. PMID 34624206 DOI: 10.1016/j.stem.2021.09.008  0.812
2021 Jönsson ME, Garza R, Sharma Y, Petri R, Södersten E, Johansson JG, Johansson PA, Atacho DA, Pircs K, Madsen S, Yudovich D, Ramakrishnan R, Holmberg J, Larsson J, Jern P, ... Jakobsson J, et al. Activation of endogenous retroviruses during brain development causes an inflammatory response. The Embo Journal. e106423. PMID 33644903 DOI: 10.15252/embj.2020106423  0.811
2020 Jönsson ME, Garza R, Johansson PA, Jakobsson J. Transposable Elements: A Common Feature of Neurodevelopmental and Neurodegenerative Disorders. Trends in Genetics : Tig. PMID 32499105 DOI: 10.1016/J.Tig.2020.05.004  0.774
2020 Brattås PL, Hersbach BA, Madsen S, Petri R, Jakobsson J, Pircs K. Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease. Autophagy. 1-14. PMID 32374203 DOI: 10.1080/15548627.2020.1760014  0.363
2020 Grassi DA, Brattås PL, Jönsson ME, Atacho D, Karlsson O, Nolbrant S, Parmar M, Jakobsson J. Profiling of lincRNAs in human pluripotent stem cell derived forebrain neural progenitor cells. Heliyon. 6: e03067. PMID 31909251 DOI: 10.1016/J.Heliyon.2019.E03067  0.809
2019 Butler CR, Boychuk JA, Pomerleau F, Alcala R, Huettl P, Ai Y, Jakobsson J, Whiteheart SW, Gerhardt GA, Smith BN, Slevin JT. Modulation of epileptogenesis: A paradigm for the integration of enzyme-based microelectrode arrays and optogenetics. Epilepsy Research. 159: 106244. PMID 31816591 DOI: 10.1016/J.Eplepsyres.2019.106244  0.366
2019 Sabelström H, Petri R, Shchors K, Jandial R, Schmidt C, Sacheva R, Masic S, Yuan E, Fenster T, Martinez M, Saxena S, Nicolaides TP, Ilkhanizadeh S, Berger MS, Snyder EY, ... ... Jakobsson J, et al. Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness. Cell Reports. 28: 2064-2079.e11. PMID 31433983 DOI: 10.1016/J.Celrep.2019.07.071  0.401
2019 Jönsson ME, Ludvik Brattås P, Gustafsson C, Petri R, Yudovich D, Pircs K, Verschuere S, Madsen S, Hansson J, Larsson J, Månsson R, Meissner A, Jakobsson J. Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors. Nature Communications. 10: 3182. PMID 31320637 DOI: 10.1038/S41467-019-11150-8  0.794
2019 Petri R, Brattås PL, Sharma Y, Jönsson ME, Pircs K, Bengzon J, Jakobsson J. LINE-2 transposable elements are a source of functional human microRNAs and target sites. Plos Genetics. 15: e1008036. PMID 30865625 DOI: 10.1371/Journal.Pgen.1008036  0.777
2018 Kutsche LK, Gysi DM, Fallmann J, Lenk K, Petri R, Swiersy A, Klapper SD, Pircs K, Khattak S, Stadler PF, Jakobsson J, Nowick K, Busskamp V. Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis. Cell Systems. PMID 30292704 DOI: 10.1016/J.Cels.2018.08.011  0.416
2018 Pircs K, Petri R, Madsen S, Brattås PL, Vuono R, Ottosson DR, St-Amour I, Hersbach BA, Matusiak-Brückner M, Lundh SH, Petersén Å, Déglon N, Hébert SS, Parmar M, Barker RA, ... Jakobsson J, et al. Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation. Cell Reports. 24: 1397-1406. PMID 30089251 DOI: 10.1016/J.Celrep.2018.07.017  0.569
2018 Grassi DA, Jönsson ME, Brattås PL, Jakobsson J. TRIM28 and The Control of Transposable Elements in The Brain. Brain Research. PMID 29522722 DOI: 10.1016/J.Brainres.2018.02.043  0.798
2017 Drouin-Ouellet J, Pircs K, Barker RA, Jakobsson J, Parmar M. Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned? Frontiers in Neuroscience. 11: 530. PMID 29033781 DOI: 10.3389/Fnins.2017.00530  0.6
2017 Drouin-Ouellet J, Lau S, Brattås PL, Rylander Ottosson D, Pircs K, Grassi DA, Collins LM, Vuono R, Andersson Sjöland A, Westergren-Thorsson G, Graff C, Minthon L, Toresson H, Barker RA, Jakobsson J, et al. REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways. Embo Molecular Medicine. PMID 28646119 DOI: 10.15252/Emmm.201607471  0.622
2017 Petri R, Pircs K, Jönsson ME, Åkerblom M, Brattås PL, Klussendorf T, Jakobsson J. let-7 regulates radial migration of new-born neurons through positive regulation of autophagy. The Embo Journal. PMID 28336683 DOI: 10.15252/Embj.201695235  0.775
2017 Brattås PL, Jönsson ME, Fasching L, Nelander Wahlestedt J, Shahsavani M, Falk R, Falk A, Jern P, Parmar M, Jakobsson J. TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells. Cell Reports. 18: 1-11. PMID 28052240 DOI: 10.1016/J.Celrep.2016.12.010  0.814
2017 Sabelstrom H, Petri R, Shchors K, Jandial R, Sacheva R, Masic S, Yuan E, Fenster T, Nicolaides T, IIkhanizadeh S, Berger MS, Snyder E, Weiss W, Jakobsson J, Persson A. STEM-11. A MAPK-DRIVEN miR-124-SOX9 AXIS IS CRITICAL FOR STEM CELL MAINTENANCE, PROGRESSION, AND THERAPY-RESISTANCE IN GLIOBLASTOMA Neuro-Oncology. 19: vi228-vi228. DOI: 10.1093/Neuonc/Nox168.927  0.3
2016 Malmevik J, Petri R, Knauff P, Brattås PL, Åkerblom M, Jakobsson J. Distinct cognitive effects and underlying transcriptome changes upon inhibition of individual miRNAs in hippocampal neurons. Scientific Reports. 6: 19879. PMID 26813637 DOI: 10.1038/Srep19879  0.318
2016 Alcacer C, Sebastianutto I, Fieblinger T, Jakobsson J, Cenci A. Role of striatal projection neurons in the generation of L-DOPA-induced dyskinesia Parkinsonism & Related Disorders. 22: e90. DOI: 10.1016/J.Parkreldis.2015.10.189  0.611
2015 Fritz M, Klawonn AM, Nilsson A, Singh AK, Zajdel J, Björk Wilhelms D, Lazarus M, Löfberg A, Jaarola M, Örtegren Kugelberg U, Billiar TR, Hackam DJ, Sodhi CP, Breyer MD, Jakobsson J, et al. Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice. The Journal of Clinical Investigation. PMID 26690700 DOI: 10.1172/Jci83844  0.317
2015 Jönsson ME, Nelander Wahlestedt J, Åkerblom M, Kirkeby A, Malmevik J, Brattaas PL, Jakobsson J, Parmar M. Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor. Development (Cambridge, England). 142: 3166-77. PMID 26395143 DOI: 10.1242/Dev.122747  0.794
2015 Malmevik J, Petri R, Klussendorf T, Knauff P, Åkerblom M, Johansson J, Soneji S, Jakobsson J. Identification of the miRNA targetome in hippocampal neurons using RIP-seq. Scientific Reports. 5: 12609. PMID 26219083 DOI: 10.1038/Srep12609  0.38
2015 Grealish S, Heuer A, Cardoso T, Kirkeby A, Jönsson M, Johansson J, Björklund A, Jakobsson J, Parmar M. Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons. Stem Cell Reports. 4: 975-83. PMID 26004633 DOI: 10.1016/J.Stemcr.2015.04.011  0.791
2015 Fasching L, Kapopoulou A, Sachdeva R, Petri R, Jönsson ME, Männe C, Turelli P, Jern P, Cammas F, Trono D, Jakobsson J. TRIM28 represses transcription of endogenous retroviruses in neural progenitor cells. Cell Reports. 10: 20-8. PMID 25543143 DOI: 10.1016/J.Celrep.2014.12.004  0.81
2014 Lau S, Rylander Ottosson D, Jakobsson J, Parmar M. Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors. Cell Reports. 9: 1673-80. PMID 25482564 DOI: 10.1016/J.Celrep.2014.11.017  0.673
2014 Akerblom M, Petri R, Sachdeva R, Klussendorf T, Mattsson B, Gentner B, Jakobsson J. microRNA-125 distinguishes developmentally generated and adult-born olfactory bulb interneurons. Development (Cambridge, England). 141: 1580-8. PMID 24598163 DOI: 10.1242/Dev.101659  0.358
2014 Petri R, Malmevik J, Fasching L, Åkerblom M, Jakobsson J. miRNAs in brain development. Experimental Cell Research. 321: 84-9. PMID 24099990 DOI: 10.1016/J.Yexcr.2013.09.022  0.321
2013 Akerblom M, Jakobsson J. MicroRNAs as Neuronal Fate Determinants. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 20: 235-242. PMID 23877999 DOI: 10.1177/1073858413497265  0.348
2013 Ã…kerblom M, Sachdeva R, Quintino L, Wettergren EE, Chapman KZ, Manfre G, Lindvall O, Lundberg C, Jakobsson J. Visualization and genetic modification of resident brain microglia using lentiviral vectors regulated by microRNA-9. Nature Communications. 4: 1770. PMID 23612311 DOI: 10.1038/Ncomms2801  0.793
2013 Decressac M, Mattsson B, Weikop P, Lundblad M, Jakobsson J, Björklund A. TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity. Proceedings of the National Academy of Sciences of the United States of America. 110: E1817-26. PMID 23610405 DOI: 10.1073/Pnas.1305623110  0.726
2013 Torper O, Pfisterer U, Wolf DA, Pereira M, Lau S, Jakobsson J, Björklund A, Grealish S, Parmar M. Generation of induced neurons via direct conversion in vivo. Proceedings of the National Academy of Sciences of the United States of America. 110: 7038-43. PMID 23530235 DOI: 10.1073/Pnas.1303829110  0.837
2013 Rowe HM, Kapopoulou A, Corsinotti A, Fasching L, Macfarlan TS, Tarabay Y, Viville S, Jakobsson J, Pfaff SL, Trono D. TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells. Genome Research. 23: 452-61. PMID 23233547 DOI: 10.1101/Gr.147678.112  0.608
2012 Åkerblom M, Sachdeva R, Barde I, Verp S, Gentner B, Trono D, Jakobsson J. MicroRNA-124 is a subventricular zone neuronal fate determinant. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8879-89. PMID 22745489 DOI: 10.1523/Jneurosci.0558-12.2012  0.573
2012 Akerblom M, Sachdeva R, Jakobsson J. Functional Studies of microRNAs in Neural Stem Cells: Problems and Perspectives. Frontiers in Neuroscience. 6: 14. PMID 22347160 DOI: 10.3389/Fnins.2012.00014  0.359
2011 Grealish S, Jakobsson J, Parmar M. Lineage reprogramming: a shortcut to generating functional neurons from fibroblasts. Cell Cycle (Georgetown, Tex.). 10: 3421-2. PMID 22067653 DOI: 10.4161/Cc.10.20.17691  0.797
2011 Quenneville S, Verde G, Corsinotti A, Kapopoulou A, Jakobsson J, Offner S, Baglivo I, Pedone PV, Grimaldi G, Riccio A, Trono D. In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions. Molecular Cell. 44: 361-72. PMID 22055183 DOI: 10.1016/J.Molcel.2011.08.032  0.514
2011 Parmar M, Jakobsson J. Turning skin into dopamine neurons. Cell Research. 21: 1386-7. PMID 21826107 DOI: 10.1038/Cr.2011.130  0.647
2011 Pfisterer U, Kirkeby A, Torper O, Wood J, Nelander J, Dufour A, Björklund A, Lindvall O, Jakobsson J, Parmar M. Direct conversion of human fibroblasts to dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 108: 10343-8. PMID 21646515 DOI: 10.1073/Pnas.1105135108  0.797
2010 Sachdeva R, Jönsson ME, Nelander J, Kirkeby A, Guibentif C, Gentner B, Naldini L, Björklund A, Parmar M, Jakobsson J. Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors. Proceedings of the National Academy of Sciences of the United States of America. 107: 11602-7. PMID 20534548 DOI: 10.1073/Pnas.1006568107  0.828
2010 Rowe HM, Jakobsson J, Mesnard D, Rougemont J, Reynard S, Aktas T, Maillard PV, Layard-Liesching H, Verp S, Marquis J, Spitz F, Constam DB, Trono D. KAP1 controls endogenous retroviruses in embryonic stem cells. Nature. 463: 237-40. PMID 20075919 DOI: 10.1038/Nature08674  0.592
2009 Nielsen TT, Jakobsson J, Rosenqvist N, Lundberg C. Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants. Bmc Biotechnology. 9: 13. PMID 19239708 DOI: 10.1186/1472-6750-9-13  0.784
2008 Jakobsson J, Cordero MI, Bisaz R, Groner AC, Busskamp V, Bensadoun JC, Cammas F, Losson R, Mansuy IM, Sandi C, Trono D. KAP1-mediated epigenetic repression in the forebrain modulates behavioral vulnerability to stress. Neuron. 60: 818-31. PMID 19081377 DOI: 10.1016/J.Neuron.2008.09.036  0.585
2008 Lundberg C, Björklund T, Carlsson T, Jakobsson J, Hantraye P, Déglon N, Kirik D. Applications of lentiviral vectors for biology and gene therapy of neurological disorders. Current Gene Therapy. 8: 461-73. PMID 19075629 DOI: 10.2174/156652308786847996  0.81
2007 Wiznerowicz M, Jakobsson J, Szulc J, Liao S, Quazzola A, Beermann F, Aebischer P, Trono D. The Kruppel-associated box repressor domain can trigger de novo promoter methylation during mouse early embryogenesis. The Journal of Biological Chemistry. 282: 34535-41. PMID 17893143 DOI: 10.1074/Jbc.M705898200  0.571
2006 Jakobsson J, Rosenqvist N, MÃ¥rild K, V Agoston D, Lundberg C. Evidence for disease-regulated transgene expression in the brain with use of lentiviral vectors. Journal of Neuroscience Research. 84: 58-67. PMID 16683227 DOI: 10.1002/Jnr.20872  0.809
2006 Jakobsson J, Nielsen TT, Staflin K, Georgievska B, Lundberg C. Efficient transduction of neurons using Ross River glycoprotein-pseudotyped lentiviral vectors. Gene Therapy. 13: 966-73. PMID 16511527 DOI: 10.1038/Sj.Gt.3302701  0.822
2006 Jakobsson J, Lundberg C. Lentiviral vectors for use in the central nervous system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 484-93. PMID 16403676 DOI: 10.1016/J.Ymthe.2005.11.012  0.78
2005 Rosenqvist N, Jakobsson J, Lundberg C. Inhibition of chromatin condensation prevents transgene silencing in a neural progenitor cell line transplanted to the rat brain. Cell Transplantation. 14: 129-38. PMID 15881422 DOI: 10.3727/000000005783983188  0.806
2005 Jakobsson J, Nielsen TT, Rosenqvist N, Lundberg C. 91. Insertion of the cHS4-Insulator into Lentiviral Vectors: Use of Real-Time PCR in Order To Analyze the Effects on Transgene Expression and Viral Titre Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.097  0.799
2004 Georgievska B, Jakobsson J, Persson E, Ericson C, Kirik D, Lundberg C. Regulated delivery of glial cell line-derived neurotrophic factor into rat striatum, using a tetracycline-dependent lentiviral vector. Human Gene Therapy. 15: 934-44. PMID 15585109 DOI: 10.1089/Hum.2004.15.934  0.795
2004 Jakobsson J, Rosenqvist N, Thompson L, Barraud P, Lundberg C. Dynamics of transgene expression in a neural stem cell line transduced with lentiviral vectors incorporating the cHS4 insulator. Experimental Cell Research. 298: 611-23. PMID 15265707 DOI: 10.1016/J.Yexcr.2004.04.037  0.809
2004 Jakobsson J, Georgievska B, Ericson C, Lundberg C. Lesion-dependent regulation of transgene expression in the rat brain using a human glial fibrillary acidic protein-lentiviral vector. The European Journal of Neuroscience. 19: 761-5. PMID 14984426 DOI: 10.1111/J.0953-816X.2003.03147.X  0.827
2003 Jakobsson J, Ericson C, Rosenqvist N, Lundberg C. Lentiviral vectors. International Review of Neurobiology. 55: 111-22. PMID 12968533 DOI: 10.1016/S0074-7742(03)01004-3  0.773
2003 Jakobsson J, Ericson C, Jansson M, Björk E, Lundberg C. Targeted transgene expression in rat brain using lentiviral vectors. Journal of Neuroscience Research. 73: 876-85. PMID 12949915 DOI: 10.1002/Jnr.10719  0.841
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