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Scott A. Wildman, Ph.D. - Publications

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
 2001 University of Michigan, Ann Arbor, Ann Arbor, MI 
 2008- Washington University School of Medicine, St. Louis, MO, United States 
Area:
Pharmaceutical Chemistry
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Damalanka VC, Wildman SA, Janetka JW. Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin. Medchemcomm. 10: 1646-1655. PMID 31803403 DOI: 10.1039/C9Md00234K  0.355
2019 Zhao C, Ye Z, Ma ZX, Wildman SA, Blaszczyk SA, Hu L, Guizei IA, Tang W. A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings. Nature Communications. 10: 4015. PMID 31488839 DOI: 10.1038/S41467-019-11976-2  0.325
2019 Zhang H, Ericksen SS, Lee CP, Ananiev GE, Wlodarchak N, Yu P, Mitchell JC, Gitter A, Wright SJ, Hoffmann FM, Wildman SA, Newton MA. Predicting kinase inhibitors using bioactivity matrix derived informer sets. Plos Computational Biology. 15: e1006813. PMID 31381559 DOI: 10.1371/Journal.Pcbi.1006813  0.337
2019 Tyagi R, Elfawal MA, Wildman SA, Helander J, Bulman CA, Sakanari J, Rosa BA, Brindley PJ, Janetka JW, Aroian RV, Mitreva M. Identification of small molecule enzyme inhibitors as broad-spectrum anthelmintics. Scientific Reports. 9: 9085. PMID 31235822 DOI: 10.1038/S41598-019-45548-7  0.349
2018 Tyagi R, Maddirala AR, Elfawal M, Fischer C, Bulman C, Rosa BA, Gao X, Chugani R, Zhou M, Helander J, Brindley P, Tseng CC, Greig IR, Sakanari J, Wildman SA, et al. Small molecule inhibitors of metabolic enzymes repurposed as a new class of anthelmintics. Acs Infectious Diseases. PMID 29718656 DOI: 10.1021/Acsinfecdis.8B00090  0.343
2017 Ericksen SS, Wu H, Zhang H, Michael LA, Newton MA, Hoffmann FM, Wildman SA. Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening. Journal of Chemical Information and Modeling. PMID 28654262 DOI: 10.1021/Acs.Jcim.7B00153  0.307
2016 Simpson C, Jones NG, Hull-Ryde EA, Kireev D, Stashko M, Tang K, Janetka J, Wildman SA, Zuercher WJ, Schapira M, Hui R, Janzen W, Sibley LD. Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18. Acs Infectious Diseases. 2: 194-206. PMID 27379343 DOI: 10.1021/Acsinfecdis.5B00102  0.307
2016 Rosenberry TL, Martin PK, Nix AJ, Wildman SA, Cheung J, Snyder SA, Tan RX. Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence. Chemico-Biological Interactions. PMID 27297626 DOI: 10.1016/J.Cbi.2016.05.032  0.319
2016 Han Z, Harris PK, Karmakar P, Kim T, Owusu BY, Wildman SA, Klampfer L, Janetka JW. α-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer. Chemmedchem. PMID 26889658 DOI: 10.1002/Cmdc.201500600  0.323
2016 Wang Q, Heizer E, Rosa BA, Wildman SA, Janetka JW, Mitreva M. Characterization of parasite-specific indels and their proposed relevance for selective anthelminthic drug targeting. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. PMID 26829384 DOI: 10.1016/J.Meegid.2016.01.025  0.312
2015 Franco FM, Jones DE, Harris PK, Han Z, Wildman SA, Jarvis CM, Janetka JW. Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets. Bioorganic & Medicinal Chemistry. 23: 2328-43. PMID 25882520 DOI: 10.1016/J.Bmc.2015.03.072  0.371
2014 Han Z, Harris PK, Jones DE, Chugani R, Kim T, Agarwal M, Shen W, Wildman SA, Janetka JW. Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer. Acs Medicinal Chemistry Letters. 5: 1219-24. PMID 25408834 DOI: 10.1021/Ml500254R  0.318
2014 Janetka J, Han Z, Harris P, Wildman S. Abstract 2523: Mechanism-based inhibitors of HGFA, matriptase and hepsin for breast cancer treatment Cancer Research. 74: 2523-2523. DOI: 10.1158/1538-7445.Am2014-2523  0.318
2013 Lourido S, Zhang C, Lopez MS, Tang K, Barks J, Wang Q, Wildman SA, Shokat KM, Sibley LD. Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii. Journal of Medicinal Chemistry. 56: 3068-77. PMID 23470217 DOI: 10.1021/Jm4001314  0.318
2010 Han Z, Pinkner JS, Ford B, Obermann R, Nolan W, Wildman SA, Hobbs D, Ellenberger T, Cusumano CK, Hultgren SJ, Janetka JW. Structure-based drug design and optimization of mannoside bacterial FimH antagonists. Journal of Medicinal Chemistry. 53: 4779-92. PMID 20507142 DOI: 10.1021/Jm100438S  0.309
2008 Sciabola S, Stanton RV, Wittkopp S, Wildman S, Moshinsky D, Potluri S, Xi H. Predicting kinase selectivity profiles using Free-Wilson QSAR analysis Journal of Chemical Information and Modeling. 48: 1851-1867. PMID 18717582 DOI: 10.1021/Ci800138N  0.334
2003 Wildman SA, Crippen GM. Validation of DAPPER for 3D QSAR: conformational search and chirality metric. Journal of Chemical Information and Computer Sciences. 43: 629-36. PMID 12653531 DOI: 10.1021/Ci0256081  0.551
2002 Wildman SA, Crippen GM. Three-dimensional molecular descriptors and a novel QSAR method. Journal of Molecular Graphics & Modelling. 21: 161-70. PMID 12463634 DOI: 10.1016/S1093-3263(02)00147-X  0.584
2001 Wildman SA, Crippen GM. Evaluation of ligand overlap by atomic parameters. Journal of Chemical Information and Computer Sciences. 41: 446-50. PMID 11277735 DOI: 10.1021/Ci0000880  0.567
1999 Wildman SA, Crippen GM. Prediction of physicochemical parameters by atomic contributions Journal of Chemical Information and Computer Sciences. 39: 868-873.  0.563
1997 Wildman SA, DiLabio GA, Christiansen PA. Accurate relativistic effective potentials for the sixth-row main group elements Journal of Chemical Physics. 107: 9975-9979. DOI: 10.1063/1.475301  0.596
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