Helen R. Josephine, Ph.D. - Publications

2006 Wesleyan University, Middletown, CT, United States 

10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Bruzzese FJ, Milhollen MA, Gavin JM, Josephine HR, Brownell JE. Identification and application of NEDD8 E1 inhibitors. Methods in Molecular Biology (Clifton, N.J.). 832: 577-88. PMID 22350913 DOI: 10.1007/978-1-61779-474-2_40  0.56
2011 Riera TV, Zheng L, Josephine HR, Min D, Yang W, Hedstrom L. Allosteric activation via kinetic control: potassium accelerates a conformational change in IMP dehydrogenase. Biochemistry. 50: 8508-18. PMID 21870820 DOI: 10.1021/Bi200785S  0.56
2010 Josephine HR, Ravichandran KR, Hedstrom L. The Cys319 loop modulates the transition between dehydrogenase and hydrolase conformations in inosine 5'-monophosphate dehydrogenase. Biochemistry. 49: 10674-81. PMID 21062060 DOI: 10.1021/Bi101590C  0.56
2008 Min D, Josephine HR, Li H, Lakner C, MacPherson IS, Naylor GJ, Swofford D, Hedstrom L, Yang W. An enzymatic atavist revealed in dual pathways for water activation. Plos Biology. 6: e206. PMID 18752347 DOI: 10.1371/Journal.Pbio.0060206  0.56
2008 Riera TV, Wang W, Josephine HR, Hedstrom L. A kinetic alignment of orthologous inosine-5'-monophosphate dehydrogenases. Biochemistry. 47: 8689-96. PMID 18642884 DOI: 10.1021/Bi800674A  0.56
2008 Sauvage E, Powell AJ, Heilemann J, Josephine HR, Charlier P, Davies C, Pratt RF. Crystal structures of complexes of bacterial DD-peptidases with peptidoglycan-mimetic ligands: the substrate specificity puzzle. Journal of Molecular Biology. 381: 383-93. PMID 18602645 DOI: 10.1016/J.Jmb.2008.06.012  0.56
2007 Kumar I, Josephine HR, Pratt RF. Reactions of peptidoglycan-mimetic beta-lactams with penicillin-binding proteins in vivo and in membranes. Acs Chemical Biology. 2: 620-4. PMID 17894439 DOI: 10.1021/Cb7001347  0.56
2006 Josephine HR, Charlier P, Davies C, Nicholas RA, Pratt RF. Reactivity of penicillin-binding proteins with peptidoglycan-mimetic beta-lactams: what's wrong with these enzymes? Biochemistry. 45: 15873-83. PMID 17176110 DOI: 10.1021/Bi061804F  0.56
2005 Silvaggi NR, Josephine HR, Kuzin AP, Nagarajan R, Pratt RF, Kelly JA. Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin". Journal of Molecular Biology. 345: 521-33. PMID 15581896 DOI: 10.1016/J.Jmb.2004.10.076  0.56
2004 Josephine HR, Kumar I, Pratt RF. The perfect penicillin? Inhibition of a bacterial DD-peptidase by peptidoglycan-mimetic beta-lactams. Journal of the American Chemical Society. 126: 8122-3. PMID 15225046 DOI: 10.1021/Ja048850S  0.56
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