| Year |
Citation |
Score |
| 2008 |
Min D, Josephine HR, Li H, Lakner C, MacPherson IS, Naylor GJ, Swofford D, Hedstrom L, Yang W. An enzymatic atavist revealed in dual pathways for water activation. Plos Biology. 6: e206. PMID 18752347 DOI: 10.1371/Journal.Pbio.0060206 |
0.3 |
|
| 2008 |
Riera TV, Wang W, Josephine HR, Hedstrom L. A kinetic alignment of orthologous inosine-5'-monophosphate dehydrogenases. Biochemistry. 47: 8689-96. PMID 18642884 DOI: 10.1021/Bi800674A |
0.367 |
|
| 2008 |
Sauvage E, Powell AJ, Heilemann J, Josephine HR, Charlier P, Davies C, Pratt RF. Crystal structures of complexes of bacterial DD-peptidases with peptidoglycan-mimetic ligands: the substrate specificity puzzle. Journal of Molecular Biology. 381: 383-93. PMID 18602645 DOI: 10.1016/J.Jmb.2008.06.012 |
0.645 |
|
| 2007 |
Kumar I, Josephine HR, Pratt RF. Reactions of peptidoglycan-mimetic beta-lactams with penicillin-binding proteins in vivo and in membranes. Acs Chemical Biology. 2: 620-4. PMID 17894439 DOI: 10.1021/Cb7001347 |
0.675 |
|
| 2006 |
Josephine HR, Charlier P, Davies C, Nicholas RA, Pratt RF. Reactivity of penicillin-binding proteins with peptidoglycan-mimetic beta-lactams: what's wrong with these enzymes? Biochemistry. 45: 15873-83. PMID 17176110 DOI: 10.1021/Bi061804F |
0.675 |
|
| 2005 |
Silvaggi NR, Josephine HR, Kuzin AP, Nagarajan R, Pratt RF, Kelly JA. Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin". Journal of Molecular Biology. 345: 521-33. PMID 15581896 DOI: 10.1016/J.Jmb.2004.10.076 |
0.622 |
|
| 2004 |
Josephine HR, Kumar I, Pratt RF. The perfect penicillin? Inhibition of a bacterial DD-peptidase by peptidoglycan-mimetic beta-lactams. Journal of the American Chemical Society. 126: 8122-3. PMID 15225046 DOI: 10.1021/Ja048850S |
0.646 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2010 |
Josephine HR, Ravichandran KR, Hedstrom L. The Cys319 loop modulates the transition between dehydrogenase and hydrolase conformations in inosine 5'-monophosphate dehydrogenase. Biochemistry. 49: 10674-81. PMID 21062060 DOI: 10.1021/Bi101590C |
0.295 |
|
| 2011 |
Riera TV, Zheng L, Josephine HR, Min D, Yang W, Hedstrom L. Allosteric activation via kinetic control: potassium accelerates a conformational change in IMP dehydrogenase. Biochemistry. 50: 8508-18. PMID 21870820 DOI: 10.1021/Bi200785S |
0.281 |
|
| 2019 |
Lin J, Lu W, Caravella JA, Campbell AM, Diebold RB, Ericsson A, Fritzen E, Gustafson GR, Lancia DR, Shelekhin T, Wang Z, Castro J, Clarke A, Gotur D, Josephine HR, et al. Discovery and Optimization of Quinolinone Derivatives as Potent, Selective and Orally Bioavailable mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors. Journal of Medicinal Chemistry. PMID 31199148 DOI: 10.1021/acs.jmedchem.9b00362 |
0.213 |
|
| 2012 |
Bruzzese FJ, Milhollen MA, Gavin JM, Josephine HR, Brownell JE. Identification and application of NEDD8 E1 inhibitors. Methods in Molecular Biology (Clifton, N.J.). 832: 577-88. PMID 22350913 DOI: 10.1007/978-1-61779-474-2_40 |
0.202 |
|
| 2007 |
Millward SW, Lamichhane TN, Mahto SK, Kumar I, Josephine HR. Introducing our Authors Acs Chemical Biology. 2: 579-579. DOI: 10.1021/Cb700187C |
0.165 |
|
| 2020 |
Caravella JA, Lin J, Diebold RB, Campbell AM, Ericsson A, Gustafson G, Wang Z, Castro J, Clarke A, Gotur D, Josephine HR, Katz M, Kershaw M, Yao L, Toms AV, et al. Structure-based design and identification of FT-2102 (olutasidenib), a potent mutant-selective IDH1 inhibitor. Journal of Medicinal Chemistry. PMID 31971798 DOI: 10.1021/acs.jmedchem.9b01423 |
0.114 |
|
| Hide low-probability matches. |